250 results on '"John A. Batsis"'
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2. Patient characteristics and utilization of an online patient portal in a rural academic general internal medicine practice
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Stephen K. Liu, Annette E. Osborn, Sigall Bell, John N. Mecchella, Shoshana Hort, and John A. Batsis
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Patient portal ,Disparities ,Rural ,Health information ,Computer applications to medicine. Medical informatics ,R858-859.7 - Abstract
Abstract Background Online patient portals have the potential to improve patient engagement and health care outcomes. This is especially true among rural patient populations that may live far from their health care providers and for whom transportation is a barrier to accessing care. This study compared the characteristics of active users of an online patient portal to non-users and assessed utilization among users in a rural academic primary care clinic to identify disparities in adoption and use. Methods We conducted a cross sectional study of 28,028 patients in a general internal medicine clinic between June 2019 and May 2020 to assess (a) characteristics of patients who had an online patient portal account and used the patient portal compared to those who did not register for an account, and (b) the frequency of use of the patient portal (number of logons and number of messages sent and received) by patients over the study period. We compared results based on demographic characteristics, focusing on gender, age, race, presence or absence of nine chronic illnesses, smoking status, and BMI. Results In the study cohort of 28,028 patients, 82% were active users of the patient portal. Females, patients aged 41–65, and non-smokers were more likely to use the portal than their counterparts. In total, patients with eight out of nine chronic illness groups studied (heart failure, cerebrovascular disease, history of a myocardial infarction, peripheral vascular disease, and renal disease) were less likely to use the patient portal than patients without these chronic conditions. On average, patients log onto the patient portal 25 times per year and send and receive 6 messages to and from the clinic. We found that females, patients older than 65, former smokers and obese patients logged on and sent and received more messages compared to the overall cohort. Although the sample size was small, on average Black patients logged onto the patient portal 19 times and sent and received 3.6 messages compared to White patients who logged on 25 times with 5.8 messages on average over the yearlong study period. Conclusions In a rural academic internal medicine clinic, female patients, aged 41–65, non-smokers, and those without certain chronic conditions were more likely to use an online patient portal. Recognizing and addressing barriers to patient portal use is essential for robust and sustained patient portal uptake and ensuring that the benefits of portal use are equally distributed among all patients.
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- 2022
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3. Definition and Diagnostic Criteria for Sarcopenic Obesity: ESPEN and EASO Consensus Statement
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Lorenzo M. Donini, Luca Busetto, Stephan C. Bischoff, Tommy Cederholm, Maria D. Ballesteros-Pomar, John A. Batsis, Juergen M. Bauer, Yves Boirie, Alfonso J. Cruz-Jentoft, Dror Dicker, Stefano Frara, Gema Frühbeck, Laurence Genton, Yftach Gepner, Andrea Giustina, Maria Cristina Gonzalez, Ho-Seong Han, Steven B. Heymsfield, Takashi Higashiguchi, Alessandro Laviano, Andrea Lenzi, Ibolya Nyulasi, Edda Parrinello, Eleonora Poggiogalle, Carla M. Prado, Javier Salvador, Yves Rolland, Ferruccio Santini, Mireille J. Serlie, Hanping Shi, Cornel C. Sieber, Mario Siervo, Roberto Vettor, Dennis T. Villareal, Dorothee Volkert, Jianchun Yu, Mauro Zamboni, and Rocco Barazzoni
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obesity ,sarcopenia ,sarcopenic obesity ,Nutrition. Foods and food supply ,TX341-641 ,Nutritional diseases. Deficiency diseases ,RC620-627 - Abstract
Introduction: Loss of skeletal muscle mass and function (sarcopenia) is common in individuals with obesity due to metabolic changes associated with a sedentary lifestyle, adipose tissue derangements, comorbidities (acute and chronic diseases) and during the ageing process. Co-existence of excess adiposity and low muscle mass/function is referred to as sarcopenic obesity (SO), a condition increasingly recognized for its clinical and functional features that negatively influence important patient-centred outcomes. Effective prevention and treatment strategies for SO are urgently needed, but efforts are hampered by the lack of a universally established SO definition and diagnostic criteria. Resulting inconsistencies in the literature also negatively affect the ability to define prevalence as well as clinical relevance of SO for negative health outcomes. Aims and Methods: The European Society for Clinical Nutrition and Metabolism (ESPEN) and the European Association for the Study of Obesity (EASO) launched an initiative to reach expert consensus on a definition and diagnostic criteria for SO. The jointly appointed international expert panel proposes that SO is defined as the co-existence of excess adiposity and low muscle mass/function. The diagnosis of SO should be considered in at-risk individuals who screen positive for a co-occurring elevated body mass index or waist circumference, and markers of low skeletal muscle mass and function (risk factors, clinical symptoms, or validated questionnaires). Diagnostic procedures should initially include assessment of skeletal muscle function, followed by assessment of body composition where presence of excess adiposity and low skeletal muscle mass or related body compartments confirm the diagnosis of SO. Individuals with SO should be further stratified into stage I in the absence of clinical complications or stage II if cases are associated with complications linked to altered body composition or skeletal muscle dysfunction. Conclusions: ESPEN and EASO, as well as the expert international panel, advocate that the proposed SO definition and diagnostic criteria be implemented into routine clinical practice. The panel also encourages prospective studies in addition to secondary analysis of existing data sets, to study the predictive value, treatment efficacy and clinical impact of this SO definition.
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- 2022
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4. Wearable sensor-based performance status assessment in cancer: A pilot multicenter study from the Alliance for Clinical Trials in Oncology (A19_Pilot2)
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William A. Wood, Deepika Dilip, Andriy Derkach, Natalie S. Grover, Olivier Elemento, Ross Levine, Gita Thanarajasingam, John A. Batsis, Charlotte Bailey, Arun Kannappan, Steven M. Devine, Andrew S. Artz, Jennifer A. Ligibel, Ethan Basch, Erin Kent, and Jacob Glass
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Computer applications to medicine. Medical informatics ,R858-859.7 - Abstract
Clinical performance status is designed to be a measure of overall health, reflecting a patient’s physiological reserve and ability to tolerate various forms of therapy. Currently, it is measured by a combination of subjective clinician assessment and patient-reported exercise tolerance in the context of daily living activities. In this study, we assess the feasibility of combining objective data sources and patient-generated health data (PGHD) to improve the accuracy of performance status assessment during routine cancer care. Patients undergoing routine chemotherapy for solid tumors, routine chemotherapy for hematologic malignancies, or hematopoietic stem cell transplant (HCT) at one of four sites in a cancer clinical trials cooperative group were consented to a six-week prospective observational clinical trial (NCT02786628). Baseline data acquisition included cardiopulmonary exercise testing (CPET) and a six-minute walk test (6MWT). Weekly PGHD included patient-reported physical function and symptom burden. Continuous data capture included use of a Fitbit Charge HR (sensor). Baseline CPET and 6MWT could only be obtained in 68% of study patients, suggesting low feasibility during routine cancer treatment. In contrast, 84% of patients had usable fitness tracker data, 93% completed baseline patient-reported surveys, and overall, 73% of patients had overlapping sensor and survey data that could be used for modeling. A linear model with repeated measures was constructed to predict the patient-reported physical function. Sensor-derived daily activity, sensor-derived median heart rate, and patient-reported symptom burden emerged as strong predictors of physical function (marginal R2 0.429–0.433, conditional R2 0.816–0.822). Trial Registration: Clinicaltrials.gov IdNCT02786628. Author summary Performance status acquisition relies on clinician judgment though additional data sources could inform its assessment. Physical performance testing is safe in patients with cancer undergoing treatment, though the feasibility of obtaining cardiopulmonary exercise testing during routine care is unclear. Patient-generated health data acquisition during cancer treatment is feasible but the contribution of these data to understanding performance status is not known. In this multicenter observational study, we used fitness trackers in addition to validated survey instruments as a means of remotely and continuously monitoring patient physical function, a concept closely related to performance status. We found that this approach was more feasible than advanced physical performance testing during routine cancer care. Daily physical activity, heart rate, and patient-reported symptom burden provided meaningful information relevant to physical function. Prospective studies analyzing these data in the context of clinical endpoints are needed to determine whether this type of assessment could be used in place of traditional performance status assessment. Multicenter consortia could facilitate development of refined models in cancer patients and identify opportunities for interventions to improve clinical outcomes.
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- 2023
5. Baseline Serum Biomarkers Predict Response to a Weight Loss Intervention in Older Adults with Obesity: A Pilot Study
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David H. Lynch, Blake R. Rushing, Wimal Pathmasiri, Susan McRitchie, Dakota J. Batchek, Curtis L. Petersen, Danae C. Gross, Susan C. J. Sumner, and John A. Batsis
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older adults ,weight loss intervention ,biomarkers ,Microbiology ,QR1-502 - Abstract
Caloric restriction and aerobic and resistance exercise are safe and effective lifestyle interventions for achieving weight loss in the obese older population (>65 years) and may improve physical function and quality of life. However, individual responses are heterogeneous. Our goal was to explore the use of untargeted metabolomics to identify metabolic phenotypes associated with achieving weight loss after a multi-component weight loss intervention. Forty-two older adults with obesity (body mass index, BMI, ≥30 kg/m2) participated in a six-month telehealth-based weight loss intervention. Each received weekly dietitian visits and twice-weekly physical therapist-led group strength training classes with a prescription for aerobic exercise. We categorized responders’ weight loss using a 5% loss of initial body weight as a cutoff. Baseline serum samples were analyzed to determine the variable importance to the projection (VIP) of signals that differentiated the responder status of metabolic profiles. Pathway enrichment analysis was conducted in Metaboanalyst. Baseline data did not differ significantly. Weight loss was 7.2 ± 2.5 kg for the 22 responders, and 2.0 ± 2.0 kg for the 20 non-responders. Mummichog pathway enrichment analysis revealed that perturbations were most significant for caffeine and caffeine-related metabolism (p = 0.00028). Caffeine and related metabolites, which were all increased in responders, included 1,3,7-trimethylxanthine (VIP = 2.0, p = 0.033, fold change (FC) = 1.9), theophylline (VIP = 2.0, p = 0.024, FC = 1.8), paraxanthine (VIP = 2.0, p = 0.028, FC = 1.8), 1-methylxanthine (VIP = 1.9, p = 0.023, FC = 2.2), 5-acetylamino-6-amino-3-methyluracil (VIP = 2.2, p = 0.025, FC = 2.2), 1,3-dimethyl uric acid (VIP = 2.1, p = 0.023, FC = 2.3), and 1,7-dimethyl uric acid (VIP = 2.0, p = 0.035, FC = 2.2). Increased levels of phytochemicals and microbiome-related metabolites were also found in responders compared to non-responders. In this pilot weight loss intervention, older adults with obesity and evidence of significant enrichment for caffeine metabolism were more likely to achieve ≥5% weight loss. Further studies are needed to examine these associations in prospective cohorts and larger randomized trials.
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- 2023
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6. Abdominal Visceral Adipose Tissue and All-Cause Mortality: A Systematic Review
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Randa K. Saad, Malak Ghezzawi, Renee Horanieh, Assem M. Khamis, Katherine H. Saunders, John A. Batsis, and Marlene Chakhtoura
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systematic review ,visceral adipose tissue ,abdominal visceral fat ,fatal outcome ,all-cause mortality ,Diseases of the endocrine glands. Clinical endocrinology ,RC648-665 - Abstract
IntroductionIncreased abdominal visceral adipose tissue (VAT) implies an adverse cardio-metabolic profile. We examined the association of abdominal VAT parameters and all-cause mortality risk.MethodsWe systematically searched four databases. We performed citations/articles screening, data abstraction, and quality assessment in duplicate and independently (CRD42020205021).ResultsWe included 12 cohorts, the majority used computed tomography to assess abdominal VAT area. Six cohorts with a mean age ≤ 65 years, examining all-cause mortality risk per increment in VAT area (cm2) or volume (cm3), showed a 11-98% relative risk increase with higher VAT parameters. However, the association lost significance after adjusting for glycemic indices, body mass index, or other fat parameters. In 4 cohorts with a mean age >65 years, the findings on mortality were inconsistent. Conversely, in two cohorts (mean age 73-77 years), a higher VAT density, was inversely proportional to VAT area, and implied a higher mortality risk.ConclusionA high abdominal VAT area seems to be associated with increased all-cause mortality in individuals ≤ 65 years, possibly mediated by metabolic complications, and not through an independent effect. This relationship is weaker and may reverse in older individuals, most likely secondary to confounding bias and reverse causality. An individual participant data meta-analysis is needed to confirm our findings, and to define an abdominal VAT area cutoff implying increased mortality risk.Systematic Review Registrationhttps://www.crd.york.ac.uk/prospero/display_record.php?RecordID=205021, identifier CRD42020205021.
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- 2022
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7. Feasibility and acceptability of a technology-based, rural weight management intervention in older adults with obesity
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John A. Batsis, Curtis L. Petersen, Matthew M. Clark, Summer B. Cook, David Kotz, Tyler L. Gooding, Meredith N. Roderka, Rima I. Al-Nimr, Dawna Pidgeon, Ann Haedrich, K. C. Wright, Christina Aquila, and Todd A. Mackenzie
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Weight ,Telehealth ,Disparities ,Geriatrics ,RC952-954.6 - Abstract
Abstract Background Older adults with obesity residing in rural areas have reduced access to weight management programs. We determined the feasibility, acceptability and preliminary outcomes of an integrated technology-based health promotion intervention in rural-living, older adults using remote monitoring and synchronous video-based technology. Methods A 6-month, non-randomized, non-blinded, single-arm study was conducted from October 2018 to May 2020 at a community-based aging center of adults aged ≥65 years with a body mass index (BMI) ≥30 kg/m2. Weekly dietitian visits focusing on behavior therapy and caloric restriction and twice-weekly physical therapist-led group strength, flexibility and balance training classes were delivered using video-conferencing to participants in their homes. Participants used a Fitbit Alta HR for remote monitoring with data feedback provided by the interventionists. An aerobic activity prescription was provided and monitored. Results Mean age was 72.9±3.9 years (82% female). Baseline anthropometric measures of weight, BMI, and waist circumference were 97.8±16.3 kg, 36.5±5.2 kg/m2, and 115.5±13.0 cm, respectively. A total of 142 participants were screened (n=27 ineligible), and 53 consented. There were nine dropouts (17%). Overall satisfaction with the trial (4.7+ 0.6, scale: 1 (low) to 5 (high)) and with Fitbit (4.2+ 0.9) were high. Fitbit was worn an average of 81.7±19.3% of intervention days. In completers, mean weight loss was 4.6±3.5 kg or 4.7±3.5% (p
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- 2021
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8. Barriers and facilitators in implementing a pilot, pragmatic, telemedicine-delivered healthy lifestyle program for obesity management in a rural, academic obesity clinic
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John A. Batsis, Auden C. McClure, Aaron B. Weintraub, Diane Sette, Sivan Rotenberg, Courtney J. Stevens, Diane Gilbert-Diamond, David F. Kotz, Stephen J. Bartels, Summer B. Cook, and Richard I. Rothstein
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Obesity ,Telemedicine ,Rural ,Weight loss ,Pragmatic ,Medicine (General) ,R5-920 - Abstract
Abstract Purpose Few evidence-based strategies are specifically tailored for disparity populations such as rural adults. Two-way video-conferencing using telemedicine can potentially surmount geographic barriers that impede participation in high-intensity treatment programs offering frequent visits to clinic facilities. We aimed to understand barriers and facilitators of implementing a telemedicine-delivered tertiary-care, rural academic weight-loss program for the management of obesity. Methods A single-arm study of a 16-week, weight-loss pilot evaluated barriers and facilitators to program participation and exploratory measures of program adoption and staff confidence in implementation and intervention delivery. A program was delivered using video-conferencing within an existing clinical infrastructure. Elements of Consolidated Framework for Implementation Research (CFIR) provided a basis for assessing intervention characteristics, inner and outer settings, and individual characteristics using surveys and semi-structured interviews. We evaluated elements of the RE-AIM model (reach, adoption) to assess staff barriers to success for future scalability. Findings There were 27 patients and 8 staff completing measures. Using CFIR, the intervention was valuable from a patient participant standpoint; staff equally had positive feelings about using telemedicine as useful for patient care. The RE-AIM framework demonstrated limited reach but willingness to adopt was above average. A significant barrier limiting sustainability was physical space for intervention delivery and privacy and dedicated resources for staff. Scheduling stressors were also a challenge in its implementation. Conclusions The need to engage staff, enhance organizational culture, and increase reach are major factors for rural health obesity clinics to enhance sustainability of using telemedicine for the management of obesity. Trial registration Clinicaltrials.gov NCT03309787 . Registered on 16 October 2017.
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- 2020
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9. Feasibility and acceptability of a rural, pragmatic, telemedicine‐delivered healthy lifestyle programme
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John A. Batsis, Auden C. McClure, Aaron B. Weintraub, David F. Kotz, Sivan Rotenberg, Summer B. Cook, Diane Gilbert‐Diamond, Kevin Curtis, Courtney J. Stevens, Diane Sette, and Richard I. Rothstein
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obesity ,pragmatic ,rural ,telemedicine ,Internal medicine ,RC31-1245 - Abstract
Summary Background The public health crisis of obesity leads to increasing morbidity that are even more profound in certain populations such as rural adults. Live, two‐way video‐conferencing is a modality that can potentially surmount geographic barriers and staffing shortages. Methods Patients from the Dartmouth‐Hitchcock Weight and Wellness Center were recruited into a pragmatic, single‐arm, nonrandomized study of a remotely delivered 16‐week evidence‐based healthy lifestyle programme. Patients were provided hardware and appropriate software allowing for remote participation in all sessions, outside of the clinic setting. Our primary outcomes were feasibility and acceptability of the telemedicine intervention, as well as potential effectiveness on anthropometric and functional measures. Results Of 62 participants approached, we enrolled 37, of which 27 completed at least 75% of the 16‐week programme sessions (27% attrition). Mean age was 46.9 ± 11.6 years (88.9% female), with a mean body mass index of 41.3 ± 7.1 kg/m2 and mean waist circumference of 120.7 ± 16.8 cm. Mean patient participant satisfaction regarding the telemedicine approach was favourable (4.48 ± 0.58 on 1‐5 Likert scale—low to high) and 67.6/75 on standardized questionnaire. Mean weight loss at 16 weeks was 2.22 ± 3.18 kg representing a 2.1% change (P < .001), with a loss in waist circumference of 3.4% (P = .001). Fat mass and visceral fat were significantly lower at 16 weeks (2.9% and 12.5%; both P < .05), with marginal improvement in appendicular skeletal muscle mass (1.7%). In the 30‐second sit‐to‐stand test, a mean improvement of 2.46 stands (P = .005) was observed. Conclusion A telemedicine‐delivered, intensive weight loss intervention is feasible, acceptable, and potentially effective in rural adults seeking weight loss.
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- 2019
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10. Exploring Deep Transfer Learning Techniques for Alzheimer's Dementia Detection
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Youxiang Zhu, Xiaohui Liang, John A. Batsis, and Robert M. Roth
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Alzheimer's disease ,early detection ,spontaneous speech ,deep learning ,transfer learning ,Electronic computers. Computer science ,QA75.5-76.95 - Abstract
Examination of speech datasets for detecting dementia, collected via various speech tasks, has revealed links between speech and cognitive abilities. However, the speech dataset available for this research is extremely limited because the collection process of speech and baseline data from patients with dementia in clinical settings is expensive. In this paper, we study the spontaneous speech dataset from a recent ADReSS challenge, a Cookie Theft Picture (CTP) dataset with balanced groups of participants in age, gender, and cognitive status. We explore state-of-the-art deep transfer learning techniques from image, audio, speech, and language domains. We envision that one advantage of transfer learning is to eliminate the design of handcrafted features based on the tasks and datasets. Transfer learning further mitigates the limited dementia-relevant speech data problem by inheriting knowledge from similar but much larger datasets. Specifically, we built a variety of transfer learning models using commonly employed MobileNet (image), YAMNet (audio), Mockingjay (speech), and BERT (text) models. Results indicated that the transfer learning models of text data showed significantly better performance than those of audio data. Performance gains of the text models may be due to the high similarity between the pre-training text dataset and the CTP text dataset. Our multi-modal transfer learning introduced a slight improvement in accuracy, demonstrating that audio and text data provide limited complementary information. Multi-task transfer learning resulted in limited improvements in classification and a negative impact in regression. By analyzing the meaning behind the Alzheimer's disease (AD)/non-AD labels and Mini-Mental State Examination (MMSE) scores, we observed that the inconsistency between labels and scores could limit the performance of the multi-task learning, especially when the outputs of the single-task models are highly consistent with the corresponding labels/scores. In sum, we conducted a large comparative analysis of varying transfer learning models focusing less on model customization but more on pre-trained models and pre-training datasets. We revealed insightful relations among models, data types, and data labels in this research area.
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- 2021
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11. 362 Group Model Building to characterize the experiences of older adults with type 1 diabetes (T1D) with continuous glucose monitoring (CGM) therapy and uncover suboptimal response patterns
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Anna R Kahkoska, John A. Batsis, Michael R. Kosorok, Elizabeth J. Mayer-Davis, Richard Pratley, Ruth Weinstock, Laura A. Young, and Kristen Hassmiller Lich
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Medicine - Abstract
OBJECTIVES/GOALS: As the number of older adults (≥65 years) with T1D grows, there are limited data to guide care. In a six-month trial, CGM reduced hypoglycemia in older adults, yet there are challenges for widespread uptake. Our objective is to characterize older adults experiences with using CGM and define suboptimal responses signaling a need for resources or support. METHODS/STUDY POPULATION: The study will engage key stakeholders (i.e., older adults with T1D, caregivers [recruited as patient-caregiver dyads], and providers [endocrinologists, geriatricians, diabetes educators]) for a Group Model Building (GMB). GMB is a participatory approach to system dynamics in which participants share perceptions and experiences with a problem and collaboratively explore the system structure that shapes those trends. A series of 8 GMB workshops will be held with 3-8 participants. The final study n will be determined by thematic saturation. Workshops comprise 1) a questionnaire, 2) a GMB session, and 3) a focus group discussion. GMB will follow a replicable process to generate a model of the complex web of causal determinants affecting CGM-related experiences, including optimal and suboptimal CGM responses. RESULTS/ANTICIPATED RESULTS: To date, the study has enrolled 33 participants, including 28 older adults living with T1D and 5 caregivers (mean age = 74 years, range 67-83 years). Twenty-four patient participants will be active CGM users and 4 will be CGM non-users. The study will report on patient data capture from the questionnaire and EMR, including demographics, experiences, familiarity, and confidence surrounding CGM use; diabetes duration; insulin pump use; history of severe hypoglycemia. Analysis of aggregated data will generate causal loop diagrams that integrate pertinent theoretical frameworks, lived experiences, and CGM outcomes. Maps will be used to identify a set of suboptimal CGM responses (i.e., key outcome trajectories) that signal a need for action, with a diagram of factors that interact to produce each response. DISCUSSION/SIGNIFICANCE: Delivering CGM to older adults with T1D demands new approaches. This study will yield critical evidence to tailor support and resources for effective CGM use in older adults. Findings may be translated into suite of pragmatic interventions to bolster CGM use and matched to individual patients expected to benefit using a precision medicine framework.
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- 2022
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12. Telemedicine in Long-Term Care Facilities During and Beyond COVID-19: Challenges Caused by the Digital Divide
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Alexander Seifert, John A. Batsis, and Anthony C. Smith
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older adults ,telehealth ,COVID-19 ,nursing care ,telemedicine ,long-term care ,Public aspects of medicine ,RA1-1270 - Published
- 2020
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13. Sarcopenia and sarcopenic obesity: do they predict inferior oncologic outcomes after gastrointestinal cancer surgery?
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Kimberly L. Mei, John A. Batsis, Jeannine B. Mills, and Stefan D. Holubar
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Body composition ,Obesity ,Oncologic ,Sarcopenia ,Surgery ,Surgical oncology ,RD1-811 - Abstract
Abstract Sarcopenia, or loss of skeletal muscle mass and quality, has been studied as part of aging and adverse health outcomes in elderly patients but has only recently been evaluated as a separate condition in cancer patients and important indicator of adverse outcomes. Currently, its definition and method of assessment are still being debated. Sarcopenia within an increasingly obese population has led to a subgroup with sarcopenic obesity, at even higher risk of adverse outcomes. Yet, sarcopenia often goes undiagnosed in these patients, hidden beneath higher body mass index. Identifying sarcopenic and sarcopenic obese subpopulations would allow for more effective treatment plans and potential avoidance of suboptimal outcomes, as well as the chance to intervene and combat these modifiable risk factors. This review will examine available literature on the definition and methods of evaluating sarcopenia and sarcopenic obesity, summarize the effectiveness of sarcopenia and sarcopenic obesity as predictors of outcomes after gastrointestinal cancer surgery, including colorectal cancer resection, liver resection, and pancreatic resection, and outline strategies to minimize the impact of sarcopenia. It is clear that untreated sarcopenia and sarcopenic obesity can be associated with suboptimal post-operative outcomes, especially infections and disease-free or overall survival.
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- 2016
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14. Use of a Wearable Activity Device in Rural Older Obese Adults
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John A. Batsis MD, John A. Naslund MPH, Lydia E. Gill BS, Rebecca K. Masutani BS, Nayan Agarwal BS, and Stephen J. Bartels MD, MS
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Geriatrics ,RC952-954.6 - Abstract
Objective: Assess the feasibility and acceptability of Fitbit for supporting behavioral change in rural, older adults with obesity. Method: Eight adults aged ≥65 with a body mass index (BMI) ≥30kg/m 2 were recruited from a rural practice and provided a Fitbit Zip device for 30 days. Participants completed validated questionnaires/interviews. Results: Mean age was 73.4 ± 4.0 years (50% female) with a mean BMI of 34.5 ± 4.5kg/m 2 . We observed reductions in exercise confidence (sticking to it: 34.5 ± 3.3 to 30.9 ± 4.3, p = .04; making time: 18.9 ± 1.3 to 17.0 ± 2.6, p = .03) but no changes in patient activation (45.4 ± 4.3 vs. 45.0 ± 3.9). All reported high satisfaction, seven (87.5%) found Fitbit easy to use, and five (62.5%) found the feedback useful. The majority ( n = 6 [75.0%]) were mostly/very satisfied with the intervention. Consistent themes emerged regarding the benefit of self-monitoring and participant motivation. Common concerns included finding time to exercise and lack of a peer group. Conclusion: Use of Fitbit is feasible/acceptable for use among older rural obese adults but may lead to reduced confidence.
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- 2016
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15. Muscle Strength, Physical Activity, and Functional Limitations in Older Adults with Central Obesity
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Cassandra M. Germain, John A. Batsis, Elizabeth Vasquez, and Douglas R. McQuoid
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Geriatrics ,RC952-954.6 - Abstract
Background. Obesity and muscle weakness are independently associated with increased risk of physical and functional impairment in older adults. It is unknown whether physical activity (PA) and muscle strength combined provide added protection against functional impairment. This study examines the association between muscle strength, PA, and functional outcomes in older adults with central obesity. Methods. Prevalence and odds of physical (PL), ADL, and IADL limitation were calculated for 6,388 community dwelling adults aged ≥ 60 with central obesity. Individuals were stratified by sex-specific hand grip tertiles and PA. Logistic models were adjusted for age, education, comorbidities, and body-mass index and weighted. Results. Overall prevalence of PL and ADL and IADL limitations were progressively lower by grip category. Within grip categories, prevalence was lower for individuals who were active than those who were inactive. Adjusted models showed significantly lower odds of PL OR 0.42 [0.31, 0.56]; ADL OR 0.60 [0.43, 0.84], and IADL OR 0.46 [0.35, 0.61] for those in the highest grip strength category as compared to those in the lowest grip category. Conclusion. Improving grip strength in obese elders who are not able to engage in traditional exercise is important for reducing odds of physical and functional impairment.
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- 2016
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16. VPASS: Voice Privacy Assistant System for Monitoring In-home Voice Commands.
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Bang Tran, Sai Harshavardhan Reddy Kona, Xiaohui Liang, Gabriel Ghinita, Caroline Summerour, and John A. Batsis
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- 2023
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17. Early Detection of Cognitive Decline Using Voice Assistant Commands.
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Eli Kurtz, Youxiang Zhu, Tiffany M. Driesse, Bang Tran, John A. Batsis, Robert M. Roth, and Xiaohui Liang
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- 2023
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18. Domain-aware Intermediate Pretraining for Dementia Detection with Limited Data.
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Youxiang Zhu, Xiaohui Liang, John A. Batsis, and Robert M. Roth
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- 2022
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19. Towards Interpretability of Speech Pause in Dementia Detection Using Adversarial Learning.
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Youxiang Zhu, Bang Tran, Xiaohui Liang, John A. Batsis, and Robert M. Roth
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- 2022
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20. Voice-Assisted Food Recall Using Voice Assistants.
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Xiaohui Liang, John A. Batsis, Jing Yuan, Youxiang Zhu, Tiffany M. Driesse, and Josh Schultz
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- 2022
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21. WavBERT: Exploiting Semantic and Non-Semantic Speech Using Wav2vec and BERT for Dementia Detection.
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Youxiang Zhu, Abdelrahman Obyat, Xiaohui Liang, John A. Batsis, and Robert M. Roth
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- 2021
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22. BandPass: A Bluetooth-Enabled Remote Monitoring Device for Sarcopenia.
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Suehayla Mohieldin, Colin M. Minor, Curtis L. Petersen, John A. Batsis, and Ryan J. Halter
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- 2021
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23. Experience: Design, Development and Evaluation of a Wearable Device for mHealth Applications.
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George Boateng, Vivian Genaro Motti, Varun Mishra 0001, John A. Batsis, Josiah D. Hester, and David Kotz
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- 2019
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24. GeriActive: Wearable app for monitoring and encouraging physical activity among older adults.
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George Boateng, John A. Batsis, Patrick Proctor, Ryan J. Halter, and David Kotz
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- 2018
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25. ActivityAware: An app for real-time daily activity level monitoring on the Amulet wrist-worn device.
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George Boateng, John A. Batsis, Ryan J. Halter, and David Kotz
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- 2017
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26. Remote Rehabilitation: A Field-Based Feasibility Study of an mHealth Resistance Exercise Band.
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Curtis L. Petersen, Colin M. Minor, Suehayla Mohieldin, Linda G. Park, Ryan J. Halter, and John A. Batsis
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- 2020
- Full Text
- View/download PDF
27. Detection and Monitoring of Repetitions Using an mHealth-Enabled Resistance Band.
- Author
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Curtis L. Petersen, Emily V. Wechsler, Ryan J. Halter, George G. Boateng, Patrick O. Proctor, David F. Kotz, Summer B. Cook, and John A. Batsis
- Published
- 2018
- Full Text
- View/download PDF
28. <scp>Sarcopenia Definition</scp> Outcome Consortium – defined Weakness and Risk of Falls: The National Health and Aging Trends Survey
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John A. Batsis, Christian Haudenschild, Rebecca S. Crow, Meredith Gilliam, and Todd A. Mackenzie
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General Medicine - Published
- 2023
29. Individualized interventions and precision health: Lessons learned from a systematic review and implications for <scp>analytics‐driven</scp> geriatric research
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Anna R. Kahkoska, Nikki L. B. Freeman, Emily P. Jones, Daniela Shirazi, Sydney Browder, Annie Page, John Sperger, Tarek M. Zikry, Fei Yu, Jan Busby‐Whitehead, Michael R. Kosorok, and John A. Batsis
- Subjects
Geriatrics and Gerontology - Abstract
Older adults are characterized by profound clinical heterogeneity. When designing and delivering interventions, there exist multiple approaches to account for heterogeneity. We present the results of a systematic review of data-driven, personalized interventions in older adults, which serves as a use case to distinguish the conceptual and methodologic differences between individualized intervention delivery and precision health-derived interventions. We define individualized interventions as those where all participants received the same parent intervention, modified on a case-by-case basis and using an evidence-based protocol, supplemented by clinical judgment as appropriate, while precision health-derived interventions are those that tailor care to individuals whereby the strategy for how to tailor care was determined through data-driven, precision health analytics. We discuss how their integration may offer new opportunities for analytics-based geriatric medicine that accommodates individual heterogeneity but allows for more flexible and resource-efficient population-level scaling.
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- 2022
30. Validation of Resting Energy Expenditure Equations in Older Adults with Obesity
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Rachel Griffith, Ryan Shean, Curtis L. Petersen, Rima I. Al-Nimr, Tyler Gooding, Meredith N. Roderka, and John A. Batsis
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Nutrition and Dietetics ,Predictive Value of Tests ,Weight Loss ,Humans ,Reproducibility of Results ,Basal Metabolism ,Obesity ,Geriatrics and Gerontology ,Energy Metabolism ,Article ,Aged ,Body Mass Index - Abstract
It is unclear which energy expenditure prediction equation should guide weight loss interventions in older adults with obesity. We ascertained the validity of four equations commonly used in practice in a series of weight loss studies of adults aged ≥65 with a body mass index ≥30kg/m(2) using indirect calorimetry data. Diagnostic accuracy was defined as
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- 2022
31. The relationship between multimorbidity, obesity and functional impairment in older adults
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David H. Lynch, Curtis L. Petersen, Marco M. Fanous, Hillary B. Spangler, Anna R. Kahkoska, Daniel Jimenez, and John A. Batsis
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Aging ,Chronic Disease ,Humans ,Multimorbidity ,Comorbidity ,Obesity ,Geriatrics and Gerontology ,Article ,United States ,Aged ,Body Mass Index - Abstract
BACKGROUND: Declining mortality rates and an aging population have contributed to increasing rates of multimorbidity (MM) in the United States. MM is strongly associated with a decline in physical function. Obesity is an important risk factor for the development of MM, and its prevalence continues to rise. Our study aimed to evaluate the associations between obesity, MM, and rates of functional limitations in older adults. METHODS: We analyzed body mass index (BMI) and self-reported comorbidity data from 7,261 individuals aged ≥ 60 years from the National Health and Nutrition Examination Surveys 2005–2014. Weight status was defined based on standard BMI categories. MM was defined as 2 or more comorbidities, while functional limitations were self-reported. Adjusted logistic regression quantified the association between standard BMI categories and MM. We also examined the difference in the prevalence of limitations between those with and without MM. RESULTS: The overall proportion of individuals with concomitant MM and obesity was 27.0%. Compared to a normal BMI, older adults with obesity had higher odds of MM (Prevalence odds ratio 1.79, 95% CI 1.49, 2.12). Overall, 67.5% of patients with MM also reported a functional limitation, with rates of functional limitation increasing with increasing BMI. When evaluating functional limitations in those with MM by BMI class, 90% of patients classified as severely obese (BMI ≥ 40 kg/m(2)) with MM also had a concomitant functional limitation. CONCLUSIONS: Compared to normal weight status, obesity is associated with an increased burden of MM and functional limitation among older adults. Our results underscore the importance of identifying and addressing obesity, MM, and functional limitation patterns and the need for evidence-based interventions that address all three conditions in this population.
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- 2022
32. Association Between Weight Status and Rate of Cognitive Decline: China Health and Nutrition Survey 1997–2018
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David H Lynch, Annie Green Howard, Hsiao-Chuan Tien, Shufa Du, Bing Zhang, Huijun Wang, Penny Gordon-Larsen, and John A Batsis
- Subjects
Aging ,Geriatrics and Gerontology - Abstract
Background There is a close relationship between weight status and cognitive impairment in older adults. This study examined the association between weight status and the trajectory of cognitive decline over time in a population-based cohort of older adults in China. Methods We used data from adults aged ≥55 years participating in the China health and nutrition survey (1997–2018). Underweight (body mass index [BMI] ≤ 18.5 kg/m2), normal weight (18.5–23 kg/m2), overweight (23–27.5 kg/m2), and obesity (BMI ≥ 27.5 kg/m2) were defined using the World Health Organization Asian cutpoints. Global cognition was estimated every 2–4 years through a face-to-face interview using a modified telephone interview for cognitive status (scores 0–27). The association between BMI and the rate of global cognitive decline, using a restricted cubic spline for age and age category, was examined with linear mixed-effects models accounting for correlation within communities and individuals. Results We included 5 992 adults (53% female participants, mean age of 62 at baseline). We found differences in the adjusted rate of global cognitive decline by weight status (p = .01 in the cubic spline model). Models were adjusted for sex, marital status, current employment status, income, region, urbanization, education status, birth cohort, leisure activity, smoking status, and self-reported diagnosis of hypertension, diabetes, or Myocardial Infarction (MI)/stroke. In addition, significant declines by age in global cognitive function were found for all weight status categories except individuals with obesity. Conclusions In a cohort of adults in China, cognitive decline trajectory differed by weight status. A slower rate of change was observed in participants classified as having obesity.
- Published
- 2023
33. Sarcopenic obesity research perspectives outlined by the sarcopenic obesity global leadership initiative (SOGLI) - Proceedings from the SOGLI consortium meeting in rome November 2022
- Author
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Gianluca Gortan Cappellari, Christelle Guillet, Eleonora Poggiogalle, Maria D. Ballesteros Pomar, John A. Batsis, Yves Boirie, Irene Breton, Stefano Frara, Laurence Genton, Yftach Gepner, Maria Cristina Gonzalez, Steven B. Heymsfield, Eva Kiesswetter, Alessandro Laviano, Carla M. Prado, Ferruccio Santini, Mireille J. Serlie, Mario Siervo, Dennis T. Villareal, Dorothee Volkert, Trudy Voortman, Peter JM. Weijs, Mauro Zamboni, Stephan C. Bischoff, Luca Busetto, Tommy Cederholm, Rocco Barazzoni, Lorenzo M. Donini, Anja Bosy-Westphal, Amelia Brunani, Paolo Capodaglio, Dario Coletti, Elisabetta Ferretti, Francesco Frigerio, Andrea Giustina, Andrea Lenzi, Elisabetta Marini, Silvia Migliaccio, Marianna Minnetti, Edoardo Mocini, Tatiana Moro, Maurizio Muscaritoli, Philippe Noirez, Antonio Paoli, Mariangela Rondanelli, Auralia Rughetti, Josje D. Schoufour, Anna Skalska, Eva Topinkova, Hidekata Wakabayashi, Jianchun Yu, Epidemiology, Endocrinology, AGEM - Amsterdam Gastroenterology Endocrinology Metabolism, Internal medicine, AMS - Ageing & Vitality, and APH - Aging & Later Life
- Subjects
Sarcopenia ,Nutrition and Dietetics ,Consensus ,Sarcopenic obesity ,SDG 3 - Good Health and Well-being ,Obesity ,Critical Care and Intensive Care Medicine - Abstract
The European Society for Clinical Nutrition and Metabolism (ESPEN) and the European Association for the Study of Obesity (EASO) launched the Sarcopenic Obesity Global Leadership Initiative (SOGLI) to reach expert consensus on a definition and diagnostic criteria for Sarcopenic Obesity (SO). The present paper describes the proceeding of the Sarcopenic Obesity Global Leadership Initiative (SOGLI) meeting that was held on November 25th and 26th, 2022 in Rome, Italy. This consortium involved the participation of 50 researchers from different geographic regions and countries. The document outlines an agenda advocated by the SOGLI expert panel regarding the pathophysiology, screening, diagnosis, staging and treatment of SO that needs to be prioritized for future research in the field.
- Published
- 2023
34. Impact of whey protein supplementation in a weight-loss intervention in rural dwelling adults: A feasibility study
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Rima Itani Al-Nimr, Roger A. Fielding, Dawna Pidgeon, Summer B. Cook, John A. Batsis, Tiffany M. Driesse, and Curtis L. Petersen
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medicine.medical_specialty ,Whey protein ,Nutrition and Dietetics ,business.industry ,Endocrinology, Diabetes and Metabolism ,Osteoporosis ,Context (language use) ,medicine.disease ,Obesity ,Article ,Grip strength ,Whey Proteins ,Weight loss ,Whey ,Sarcopenia ,Dietary Supplements ,Weight Loss ,medicine ,Physical therapy ,Feasibility Studies ,Humans ,medicine.symptom ,Aftertaste ,business ,Aged - Abstract
Summary Background & aims Weight loss in older adults enhances physical function, but may lead to sarcopenia and osteoporosis. Whey protein is a low cost rich source of essential amino acids, may improve physical function. We evaluated the feasibility and acceptability of consuming whey protein in the context of a weight-loss intervention in older adults with obesity. Methods A 12-week pilot feasibility, non-randomized weight loss study of 28 older adults was conducted, consisting of individualized, weekly dietitian visits with twice weekly physical therapist-led group strengthening classes. Half consumed whey protein, three times weekly, following exercise. Preliminary efficacy measures of body composition, sit-to-stand, 6-min walk and grip strength and subjective measures of self-reported health and function were also evaluated. Results Of the 37 enrolled, 28 completed the study (50 % in the protein group). Attendance rates for protein vs. non-protein groups were 89.9 ± 11.1 % vs. 95.6 ± 3.4 % (p = 0.08). Protein consumption was high in those attending classes (90.3 %) as was compliance at home (82.6 %). Whey was pleasant (67.3 ± 22.1, range 30–100, above average), had little aftertaste, and was neither salty or sticky. All were compliant (0.64 ± 0.84, range 0–5, low = higher compliance). Both groups lost significant weight (protein vs. no protein, −3.45 ± 2.86 vs. −5.79 ± 3.08, p = 0.47); Sit-to-stand, 6-min walk, and gait speed were no different, grip strength was improved in the protein compared to the non-protein group (−2.63 kg vs. 4.29 kg; p Conclusions Our results suggest that whey protein is a low-cost and readily available nutritional supplement that can be integrated into a weight loss intervention.
- Published
- 2021
35. Long-term weight change after a technology-based weight loss intervention
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Brian S. Wood, David H. Lynch, Hillary B. Spangler, Meredith Roderka, Curtis L. Petersen, and John A. Batsis
- Subjects
Geriatrics and Gerontology - Published
- 2022
36. Medicare's annual wellness visit: 10 years of opportunities gained and lost
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Patrick P. Coll, John A. Batsis, Susan M. Friedman, and Ellen Flaherty
- Subjects
Racial Groups ,Humans ,Health Promotion ,Geriatrics and Gerontology ,Medicare ,United States ,Aged - Abstract
Medicare annual wellness visits (AWV) were initiated 10 years ago. Though AWVs emphasize on disease prevention and health promotion for older adults was a huge step forward, the current "one size fits all" approach does not adequately meet the wellness needs of a diverse population of older adults. Current AWVs do not sufficiently take into consideration the medical, psychological, functional, racial, cultural and socio-economic diversity of older adults. Updated AWVs should be tailored to meet the needs and priorities of older adults receiving them. Several geriatrics approaches to care, including geriatrics Glidepaths and the 4Ms of an Age-Friendly Health System, could help develop and guide a more patient-specific geriatrics focused approach to AWVs. Medicare's IPPE is an ideal time to advise new Medicare beneficiaries regarding what they should and should not do to maximize their ability to be healthy and functionally independent into their 80s, 90s, and 100s.
- Published
- 2022
37. Community health worker interventions for older adults with complex health needs: A systematic review
- Author
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Heather B. Blunt, Charles F. Reynolds, Tara N. Maden, Peter R. DiMilia, Kayla E. Hatchell, Meaghan A. Kennedy, Michael A. LaMantia, Jacqueline M. Kihwele, Rebecca S. Crow, Stephanie M. Kelly, Pamela J. Bagley, John A. Batsis, and S. Logan Kelly
- Subjects
Gerontology ,medicine.medical_specialty ,Population ,Psychological intervention ,law.invention ,03 medical and health sciences ,Social support ,0302 clinical medicine ,Quality of life (healthcare) ,Randomized controlled trial ,law ,medicine ,Humans ,Multiple Chronic Conditions ,030212 general & internal medicine ,education ,Aged ,Community Health Workers ,education.field_of_study ,Frailty ,business.industry ,030503 health policy & services ,Public health ,Multimorbidity ,Social Support ,Middle Aged ,Physical Functional Performance ,Mood ,Community health ,Quality of Life ,Geriatrics and Gerontology ,0305 other medical science ,business - Abstract
BACKGROUND/OBJECTIVES The number of older adults with complex health needs is growing, and this population experiences disproportionate morbidity and mortality. Interventions led by community health workers (CHWs) can improve clinical outcomes in the general adult population with multimorbidity, but few studies have investigated CHW-delivered interventions in older adults. DESIGN We systematically reviewed the impact of CHW interventions on health outcomes among older adults with complex health needs. We searched for English-language articles from database inception through April 2020 using seven databases. PROSPERO protocol registration CRD42019118761. SETTING Any U.S. or international setting, including clinical and community-based settings. PARTICIPANTS Adults aged 60 years or older with complex health needs, defined in this review as multimorbidity, frailty, disability, or high-utilization. INTERVENTIONS Interventions led by a CHW or similar role consistent with the American Public Health Association's definition of CHWs. MEASUREMENTS Pre-defined health outcomes (chronic disease measures, general health measures, treatment adherence, quality of life, or functional measures) as well as qualitative findings. RESULTS Of 5671 unique records, nine studies met eligibility criteria, including four randomized controlled trials, three quasi-experimental studies, and two qualitative studies. Target population and intervention characteristics were variable, and studies were generally of low-to-moderate methodological quality. Outcomes included mood, functional status and disability, social support, well-being and quality of life, medication knowledge, and certain health conditions (e.g., falls, cognition). Results were mixed with several studies demonstrating significant effects on mood and function, including one high-quality RCT, while others noted no significant intervention effects on outcomes. CONCLUSION CHW-led interventions may have benefit for older adults with complex health needs, but additional high-quality studies are needed to definitively determine the effectiveness of CHW interventions in this population. Integration of CHWs into geriatric clinical settings may be a strategy to deliver evidence-based interventions and improve clinical outcomes in complex older adults.
- Published
- 2021
38. Obesity, multiple chronic conditions, and the relationship with physical function: Data from the national health and aging trends survey
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Daniela Shirazi, Christian Haudenschild, David H. Lynch, Marco Fanous, Anna R. Kahkoska, Daniel Jimenez, Hillary Spangler, Tiffany Driesse, and John A. Batsis
- Subjects
Aging ,Health (social science) ,Geriatrics and Gerontology ,Gerontology - Abstract
The population of older adults living with multiple chronic conditions (MCC) continues to grow. MCC is independently associated with functional limitation and obesity. The aim of our study was to evaluate the association between obesity and MCC, and secondarily, the combined presence of obesity and functional limitations with MCC.We analyzed cross-sectional survey data from the National Health and Aging Trends Survey (NHATS) 2011 baseline data, a nationally representative Medicare beneficiary cohort of adults in the United States. We evaluated the coexistent prevalence of obesity and MCC overall, and by standard body mass index (BMI) categories. We then evaluated the prevalence of functional limitations (mobility, self-care, and household activities) and Fried-defined frailty status in persons with a BMI ≥ 30 kg/mIn the 6,600 participants, the prevalence of concurrent obesity and MCC was 30.4%. Of those with obesity, the prevalence of MCC was 84.0%, and were more likely to have MCC (adjusted OR: 2.17, 95% CI 1.86, 2.54) compared to a normal BMI. Obesity and functional limitations or frailty were more likely have MCC than individuals with obesity alone.We found that individuals with obesity is strongly associated with MCC and that functional limitations and frailty status have a greater association with having MCC than individuals with obesity without MCC. Future longitudinal analyses are needed to ascertain this relationship.
- Published
- 2023
39. Impact of Diet and Exercise on Weight and Cognition in Older Adults: A Rapid Review
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Diane Gilbert-Diamond, Tyler Gooding, Lillian M Seo, Peter R. DiMilia, Auden C. McClure, Vanessa K Rauch, Xingyi Li, Robert M. Roth, Meredith N. Roderka, and John A. Batsis
- Subjects
Gerontology ,Health (social science) ,Overweight ,Article ,03 medical and health sciences ,Cognition ,0302 clinical medicine ,Lifestyle intervention ,medicine ,Humans ,Obesity ,030212 general & internal medicine ,Exercise ,Aged ,Aged, 80 and over ,Exercise intervention ,business.industry ,Public Health, Environmental and Occupational Health ,medicine.disease ,Diet ,medicine.symptom ,business ,030217 neurology & neurosurgery - Abstract
Objective: To determine where the current literature stands in regard to diet/exercise interventions on cognition in overweight or obese individuals. Data Source: A rapid review was conducted of English-language studies published in Medline from January 1965 to January 2020. Study Inclusion and Exclusion Criteria: Included studies were intervention studies lasting ≥12 weeks, with participants aged ≥65 years, with a body mass index ≥25 kg/m2 Data Extraction: Data extracted included study population, duration, intervention design, outcomes, and results. Data Synthesis: Outcomes were qualitatively measured due to paucity of RTC. Results: 1845 citations were identified, 31 full-text articles were reviewed, and 5 studies were included. Studies had usual care control groups and combined exercise/diet intervention groups with 31-3,526 participants randomized to each arm. Mean age of participants was 69.2-83.4 years. Studies reporting on cognitive changes showed marginally significant positive changes in cognition, and those that reported BMI indicated potential improvements in cognition. Conclusions: The number of interventions assessing the combined effects of both diet and exercise is low. Future studies should evaluate the impact of combined effects to ascertain whether cognitive decline may be reversed in older adults with a BMI ≥25 kg/m2.
- Published
- 2021
40. Intensive nutrition counseling as part of a multi-component weight loss intervention improves diet quality and anthropometrics in older adults with obesity
- Author
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K.C.S. Wright, John A. Batsis, Curtis L. Petersen, Tyler Gooding, Christina L. Aquila, and Rima Itani Al-Nimr
- Subjects
Counseling ,Male ,0301 basic medicine ,medicine.medical_specialty ,Waist ,Endocrinology, Diabetes and Metabolism ,Population ,030209 endocrinology & metabolism ,Article ,Body Mass Index ,03 medical and health sciences ,0302 clinical medicine ,McNemar's test ,Weight loss ,Weight Loss ,medicine ,Humans ,Obesity ,education ,Aged ,education.field_of_study ,030109 nutrition & dietetics ,Nutrition and Dietetics ,business.industry ,Anthropometry ,medicine.disease ,Diet ,Physical therapy ,Female ,medicine.symptom ,business ,Nutrition counseling ,Body mass index - Abstract
BACKGROUND AND AIMS: Obesity significantly impacts older adults. Intensive nutrition counseling can aid in weight reduction and improve diet quality, but data are sparse in this population. The objective of this intervention is to determine how intensive nutrition counseling affects diet quality and anthropometric measures during a multi-component weight loss intervention in rural older adults with obesity. METHODS: A series of 12-week, single-arm feasibility pilots were conducted in fall 2017 and winter/spring 2018 in a community aging center in rural Northern New England. Adults were eligible if ≥65 years old with a Body Mass Index (BMI) ≥30kg/m(2). Exclusion criteria included dementia/cognitive impairment, uncontrolled psychiatric illness, weight-loss surgery, weight loss >5% in previous 6-months, life-threatening illness, palliative/hospice services, current participation in another weight-loss study/program, obesogenic medications, or presence of major chronic conditions. Participants received once-weekly nutrition counseling by a registered dietitian nutritionist (RDN), and twice-weekly exercise sessions by a physical therapist (PT). Primary outcomes were diet quality changes measured by total Rapid Eating and Activity Assessment for Patients-Short Version (REAP-S) and Automated Self-Administered 24-hour dietary recall (ASA-24). Secondary outcome measures were changes in weight (kilograms) and waist circumference (centimeters). McNemar test was conducted for all paired categorical data while paired t-tests were conducted for all paired continuous data. All analyses were conducted in R; p-value
- Published
- 2020
41. Gerotechnology for Older Adults With Cardiovascular Diseases
- Author
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Deborah S Croy, Michael P. Dorsch, Ruth M. Masterson Creber, John A. Batsis, Michael W. Rich, Karen P. Alexander, Craig J. Beavers, Nicole M. Orr, Mathew S. Maurer, Nanette K. Wenger, Ashok Krishnaswami, Spyros Kitsiou, Gwen M. Bernacki, Sanjeev P. Bhavnani, Eric D. Peterson, Mintu P. Turakhia, James N. Kirkpatrick, John A. Dodson, Andrew M. Freeman, Parag Goyal, and Daniel E. Forman
- Subjects
Gerontology ,Telemedicine ,education.field_of_study ,Palliative care ,business.industry ,Visual impairment ,Population ,Telehealth ,Disease ,030204 cardiovascular system & hematology ,Digital health ,03 medical and health sciences ,0302 clinical medicine ,Medicine ,030212 general & internal medicine ,medicine.symptom ,Disease management (health) ,Cardiology and Cardiovascular Medicine ,business ,education - Abstract
The growing population of older adults (age ≥65 years) is expected to lead to higher rates of cardiovascular disease. The expansion of digital health (encompassing telehealth, telemedicine, mobile health, and remote patient monitoring), Internet access, and cellular technologies provides an opportunity to enhance patient care and improve health outcomes—opportunities that are particularly relevant during the current coronavirus disease-2019 pandemic. Insufficient dexterity, visual impairment, and cognitive dysfunction, found commonly in older adults should be taken into consideration in the development and utilization of existing technologies. If not implemented strategically and appropriately, these can lead to inequities propagating digital divides among older adults, across disease severities and socioeconomic distributions. A systematic approach, therefore, is needed to study and implement digital health strategies in older adults. This review will focus on current knowledge of the benefits, barriers, and use of digital health in older adults for cardiovascular disease management.
- Published
- 2020
42. Addressing Obesity to Promote Healthy Aging
- Author
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Sadhana Puri, John A. Batsis, and Meredith N. Roderka
- Subjects
Gerontology ,Aging ,medicine.medical_specialty ,Population ,Article ,Healthy Aging ,03 medical and health sciences ,0302 clinical medicine ,Quality of life (healthcare) ,Weight loss ,Weight Loss ,Health care ,medicine ,Humans ,Healthy Lifestyle ,Obesity ,Cognitive decline ,education ,Exercise ,Aged ,education.field_of_study ,030214 geriatrics ,business.industry ,Public health ,medicine.disease ,Epidemiology of obesity ,Quality of Life ,Geriatrics and Gerontology ,medicine.symptom ,business ,030217 neurology & neurosurgery - Abstract
The population worldwide is aging and prevalence of obesity in this population is increasing. The range of consequences that effect these at-risk patients include increased risk of falls, fractures, reduced quality of life, and cognitive decline. This article describes the epidemiology of obesity, risks and benefits of weight loss, and importance of treating obesity to help promote healthy aging. Health care professionals should encourage older adults with obesity to implement healthy lifestyle behaviors including exercise and diet routine. Treating obesity in older adults mitigates the significant public health crisis, and reduces health care utilization and risk of long-term adverse events.
- Published
- 2020
43. Willingness to pay for a telemedicine-delivered healthy lifestyle programme
- Author
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John A. Batsis, Richard I. Rothstein, Kevin Curtis, Auden C. McClure, David Kotz, Vanessa K Rauch, Aaron B. Weintraub, and Meredith N. Roderka
- Subjects
Telemedicine ,020205 medical informatics ,business.industry ,Cost-Benefit Analysis ,Psychological intervention ,Health Informatics ,02 engineering and technology ,Article ,03 medical and health sciences ,0302 clinical medicine ,Willingness to pay ,Nursing ,Multidisciplinary approach ,Weight loss ,Weight Loss ,Videoconferencing ,0202 electrical engineering, electronic engineering, information engineering ,Humans ,Medicine ,Healthy Lifestyle ,030212 general & internal medicine ,medicine.symptom ,business ,mHealth - Abstract
Introduction Effective weight-management interventions require frequent interactions with specialised multidisciplinary teams of medical, nutritional and behavioural experts to enact behavioural change. However, barriers that exist in rural areas, such as transportation and a lack of specialised services, can prevent patients from receiving quality care. Methods We recruited patients from the Dartmouth-Hitchcock Weight & Wellness Center into a single-arm, non-randomised study of a remotely delivered 16-week evidence-based healthy lifestyle programme. Every 4 weeks, participants completed surveys that included their willingness to pay for services like those experienced in the intervention. A two-item Willingness-to-Pay survey was administered to participants asking about their willingness to trade their face-to-face visits for videoconference visits based on commute and copay. Results Overall, those with a travel duration of 31–45 min had a greater willingness to trade in-person visits for telehealth than any other group. Participants who had a travel duration less than 15 min, 16–30 min and 46–60 min experienced a positive trend in willingness to have telehealth visits until Week 8, where there was a general negative trend in willingness to trade in-person visits for virtual. Participants believed that telemedicine was useful and helpful. Conclusions In rural areas where patients travel 30–45 min a telemedicine-delivered, intensive weight-loss intervention may be a well-received and cost-effective way for both patients and the clinical care team to connect.
- Published
- 2020
44. Systematic Review of the Impact of Behavioral Health Homes on Cardiometabolic Risk Factors for Adults With Serious Mental Illness
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Matthew C. Lohman, Karen L. Fortuna, Brandi P. Cotton, Peter R. DiMilia, Sarah I. Pratt, Janet R. Cummings, Stephen J. Bartels, and John A. Batsis
- Subjects
Adult ,Gerontology ,Cardiometabolic risk ,Delivery of Health Care, Integrated ,business.industry ,Mental Disorders ,Comorbidity ,Peer support ,Mental illness ,medicine.disease ,Residential Facilities ,Article ,030227 psychiatry ,Behavioral Medicine ,03 medical and health sciences ,Psychiatry and Mental health ,0302 clinical medicine ,Systematic review ,Cardiovascular Diseases ,Risk Factors ,Quality of Life ,medicine ,Humans ,030212 general & internal medicine ,business - Abstract
OBJECTIVE: This systematic review examined the impact of health homes on cardiometabolic risk in adults with serious mental illness. METHODS: The Preferred Reporting Items for Systematic Reviews and Meta-Analyses procedures were used to conduct the systematic review. Databases were searched for peer-reviewed articles published between 1946 and August 2018 that compared health homes to a control condition (e.g., usual care, secondary data analyses using matched samples). Participants, interventions, comparisons, outcomes, and study design criteria were used to assess study eligibility. Studies were assessed for methodological quality using the Quality Assessment of Before and After Studies With No Control Group, and the Quality Assessment of Controlled Intervention Studies. RESULTS: Eighteen studies (i.e., eleven observational, four quasi-experimental, three randomized controlled trials) reported on 17 health homes. Most studies reported increases in receipt of screening for cardiometabolic risk factors and service use. There was a modest reduction in selected cardiometabolic risk factors among people with serious mental illness, but clinical outcomes varied widely among studies. DISCUSSION: Health homes are associated with increased rates of cardiometabolic screening and service use. However, improvement in cardiometabolic risk factors varied across the studies and the clinical significance of these reductions is not clear. Peer support and self-management training may represent strategies to improve cardiometabolic risk factors. CONCLUSIONS: Co-location of services may not be enough to significantly impact cardiometabolic risk factors. Health homes may have a greater impact on clinical outcomes if they include: standardized screening; peer support and self-management training; intervention components that target interdependent risk factors.
- Published
- 2020
45. Association between food insecurity and probable sarcopenia: Data from the 2011-2014 National Health and nutrition examination survey
- Author
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David H. Lynch, Curtis L. Petersen, Matthew J. Van Dongen, Hillary B. Spangler, Seth A. Berkowitz, and John A. Batsis
- Subjects
Cohort Studies ,Sarcopenia ,Nutrition and Dietetics ,Hand Strength ,Humans ,Muscle Strength ,Middle Aged ,Critical Care and Intensive Care Medicine ,Nutrition Surveys ,Article ,Aged - Abstract
BACKGROUND: Aging alters biological processes resulting in body fat redistribution, loss of lean muscle mass, and reduced muscle strength, termed sarcopenia. Nutrition is an important modifiable risk factor in the development of sarcopenia. Food insecurity refers to limited or uncertain access to enough food for an active, healthy life, and is prevalent among older adults. The objective of this study was to examine the relationship between food insecurity and probable sarcopenia in older adults. METHODS: We examined 3,632 adults ≥60 years old from the 2011–2014 National Health and Nutrition Examination Surveys (NHANES). For our analysis food insecurity was identified using the Food Security Survey Module (FSSM). The primary outcome was based on the Sarcopenia Definitions and Outcomes consortium (SDOC) definition. Secondary outcomes were based on three other different grip strength cut-offs as there is debate within the field as to the optimal definition of sarcopenia. Consistent with the revised European consensus on the definition and diagnosis of Sarcopenia (EWGSOP2) recommendations, we used the term probable sarcopenia throughout this text as definitions were based on muscle strength alone and did not include an evaluation of muscle quality. Sensitivity analyses were performed using the standard four category definition of food security. We used logistic regression to examine the association between food insecurity and sarcopenia. RESULTS: Using the Sarcopenia Definitions and Outcomes Consortium definition, 24.7% were classified as having probable sarcopenia (low grip strength); 5.5% had food insecurity and food insecurity was associated with probable sarcopenia (OR 1.51, 95%CI 1.03–2.22). Using three other definitions of probable sarcopenia, food insecurity was significantly associated with probable sarcopenia using the Foundation for the National Institute of Health definition using grip strength alone (OR 1.71, 95%CI 1.08–2.71), but food insecurity was not associated with food insecurity using definitions related to grip strength/BMI (OR 1.16, 95%CI 0.76–1.78) or grip strength/weight (OR 1.14, 95%CI 0.85–1.54). CONCLUSIONS: In this nationally representative cohort study, individuals classified as having food insecurity were more likely to have probable sarcopenia (low grip strength) compared to those with full food security. Future studies should examine whether food insecurity interventions may reduce probable sarcopenia and associated adverse outcomes.
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- 2022
46. Multimodal Diagnostic Approaches to Advance Precision Medicine in Sarcopenia and Frailty
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David H. Lynch, Hillary B. Spangler, Jason R. Franz, Rebecca L. Krupenevich, Hoon Kim, Daniel Nissman, Janet Zhang, Yuan-Yuan Li, Susan Sumner, and John A. Batsis
- Subjects
Aging ,Sarcopenia ,Nutrition and Dietetics ,Frailty ,Quality of Life ,Humans ,Obesity ,Syndrome ,Precision Medicine ,Food Science ,Aged - Abstract
Sarcopenia, defined as the loss of muscle mass, strength, and function with aging, is a geriatric syndrome with important implications for patients and healthcare systems. Sarcopenia increases the risk of clinical decompensation when faced with physiological stressors and increases vulnerability, termed frailty. Sarcopenia develops due to inflammatory, hormonal, and myocellular changes in response to physiological and pathological aging, which promote progressive gains in fat mass and loss of lean mass and muscle strength. Progression of these pathophysiological changes can lead to sarcopenic obesity and physical frailty. These syndromes independently increase the risk of adverse patient outcomes including hospitalizations, long-term care placement, mortality, and decreased quality of life. This risk increases substantially when these syndromes co-exist. While there is evidence suggesting that the progression of sarcopenia, sarcopenic obesity, and frailty can be slowed or reversed, the adoption of broad-based screening or interventions has been slow to implement. Factors contributing to slow implementation include the lack of cost-effective, timely bedside diagnostics and interventions that target fundamental biological processes. This paper describes how clinical, radiographic, and biological data can be used to evaluate older adults with sarcopenia and sarcopenic obesity and to further the understanding of the mechanisms leading to declines in physical function and frailty.
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- 2022
- Full Text
- View/download PDF
47. 'Nothing is linear': Characterizing the determinants and dynamics of CGM use in older adults with type 1 diabetes
- Author
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Anna R. Kahkoska, Cambray Smith, Sirisha Thambuluru, Joshua Weinstein, John A. Batsis, Richard Pratley, Ruth S. Weinstock, Laura A. Young, and Kristen Hassmiller Lich
- Subjects
Endocrinology ,Endocrinology, Diabetes and Metabolism ,Internal Medicine ,General Medicine - Abstract
Continuous glucose monitoring (CGM) can reduce hypoglycemia in older adults with type 1 diabetes (T1D). We aimed to characterize factors that influence effective use in this age group.Older adults with type T1D (age ≥65) and their caregivers participated in one of a series of parallel group model building workshops, a participatory approach to system dynamics involving drawing and scripted group activities. Data were synthesized in a qualitative model of the hypothesized system of factors producing distinct patterns of CGM use in older adults. The model was validated through virtual follow-up interviews.Data were collected from 33 participants (four patient-caregiver dyads, mean age 73.8±4.4 years [range 66-85 years]; 16% non-CGM users, 79% pump users). The system model delineates drivers of CGM uptake, drivers of ongoing CGM use, and feedback loops that either reinforce or counteract future CGM use. Participants emphasized the importance of different sets of feedback loops at different points in the duration of CGM use.The holistic system model underscores that factors and feedback loops driving effective CGM use in older adults are both individualized and dynamic (e.g., changing over time), suggesting opportunities for staged and tailored age-specific education and support. Short title: CGM Use in Older Adults with Type 1 Diabetes.
- Published
- 2023
48. Weight History in Clinical Practice: The State of the Science and Future Directions
- Author
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Domenica Rubino, Srividya Kidambi, Katherine H. Saunders, Marsha B. Novick, Robert F. Kushner, John A. Batsis, Florencia Halperin, Angela Golden, W. Scott Butsch, Scott Kahan, Ava Port, Taraneh Soleymani, Sriram Machineni, Nicola Davis, and Linda Shapiro Manning
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Counseling ,Gerontology ,Endocrinology, Diabetes and Metabolism ,Decision Making ,MEDLINE ,Medicine (miscellaneous) ,030209 endocrinology & metabolism ,Overweight ,03 medical and health sciences ,0302 clinical medicine ,Endocrinology ,Patient-Centered Care ,Humans ,Medicine ,Medical history ,Obesity ,030212 general & internal medicine ,Mortality ,Practice Patterns, Physicians' ,Duration (project management) ,Medical History Taking ,Nutrition and Dietetics ,business.industry ,Body Weight ,medicine.disease ,Clinical research ,Life course approach ,Body-Weight Trajectory ,Morbidity ,medicine.symptom ,business ,Health care quality - Abstract
Eliciting a weight history can provide clinically important information to aid in treatment decision-making. This view is consistent with the life course perspective of obesity and the aim of patient-centered care, one of six domains of health care quality. However, thus far, the value and practicality of including a weight history in the clinical assessment and treatment of patients with obesity have not been systematically explored. For these reasons, the Clinical Committee of The Obesity Society established a task force to review and assess the available evidence to address five key questions. It is concluded that weight history is an essential component of the medical history for patients presenting with overweight or obesity, and there are strong and emerging data that demonstrate the importance of life stage, duration of exposure to obesity, maximum BMI, and group-based trajectory modeling in predicting risk for increased morbidity and mortality. Consideration of these and other patient-specific factors may improve risk stratification and clinical decision-making for screening, counseling, and management. Recommendations are provided for the key elements that should be included in a weight history, and several needs for future clinical research are outlined.
- Published
- 2019
49. Smartwatch Step-Counting App for Older Adults: Development and Evaluation Study (Preprint)
- Author
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George Boateng, Curtis L. Petersen, David Kotz, Karen L. Fortuna, Rebecca Masutani, and John A. Batsis
- Abstract
BACKGROUND Older adults who engage in physical activity can reduce their risk of mobility and disability. Short amounts of walking can improve their quality of life, physical function, and cardiovascular health. Various programs have been implemented to encourage older adults to engage in physical activity, but sustaining their motivation continues to be a challenge. Ubiquitous devices, such as mobile phones and smartwatches, coupled with machine-learning algorithms, can potentially encourage older adults to be more physically active. Current algorithms that are deployed in consumer devices (e.g., Fitbit) are proprietary, often are not tailored to the movements of older adults and have been shown to be inaccurate in clinical settings. Few studies have developed step-counting algorithms for smartwatches – but only using data from younger adults and often validating them only in controlled laboratory settings. OBJECTIVE In this work, we sought to develop and validate a smartwatch step-counting app targeting older adults that has been evaluated in free-living settings over a long period of time (24 weeks) with a large sample (N=42). METHODS We developed and evaluated a step-counting app on the Amulet, an open-source wrist-worn device, to track the steps of older adults. The app includes algorithms to infer the level of physical activity and to count steps. We validated the step-counting algorithm with a total of 42 older adults in the lab (counting from a video recording, N= 20) and in free-living conditions — one 2-day field study (N=6) and two 12-week field studies (using the Fitbit as ground truth, N=16). During system development, we evaluated four kinds of walking patterns: normal, fast, up and down a staircase, and intermittent speed. For the field study, we evaluated various values for algorithm parameters, and subsequently evaluated the method’s performance using correlations and error rates. RESULTS The results from the usability evaluation showed that our step-counting algorithm performs well, highly correlated with the ground truth and with low error rate. For the lab study, there was stronger correlation for normal walking R2=0.5; across all activities, the Amulet was on average 3.2 (2.1%) steps lower (SD = 25.9) than video-validated steps. For the 2-day field study, the best parameter settings led to an association between Amulet and Fitbit (R2 of 0.989) and 3.1% (SD=25.1) steps lower than Fitbit, respectively. For the 12-week field study, the best parameter setting led to an R2 of 0.669. CONCLUSIONS Our findings demonstrate the importance of an iterative process in algorithm development in advance of field-based deployment. This work highlights various challenges and insights involved in developing and validating monitoring systems in real-world settings. Nonetheless, our step-counting app for older adults had good performance relative to the ground truth (a commercial Fitbit step-counter). Our app could potentially be used to improve the physical activity among older adults through accurate tracking of their step counts and in-app daily step-count goals. CLINICALTRIAL
- Published
- 2021
50. A Smartwatch Step-Counting App for Older Adults: Development and Evaluation Study
- Author
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George, Boateng, Curtis L, Petersen, David, Kotz, Karen L, Fortuna, Rebecca, Masutani, and John A, Batsis
- Abstract
Older adults who engage in physical activity can reduce their risk of mobility impairment and disability. Short amounts of walking can improve quality of life, physical function, and cardiovascular health. Various programs have been implemented to encourage older adults to engage in physical activity, but sustaining their motivation continues to be a challenge. Ubiquitous devices, such as mobile phones and smartwatches, coupled with machine-learning algorithms, can potentially encourage older adults to be more physically active. Current algorithms that are deployed in consumer devices (eg, Fitbit) are proprietary, often are not tailored to the movements of older adults, and have been shown to be inaccurate in clinical settings. Step-counting algorithms have been developed for smartwatches, but only using data from younger adults and, often, were only validated in controlled laboratory settings.We sought to develop and validate a smartwatch step-counting app for older adults and evaluate the algorithm in free-living settings over a long period of time.We developed and evaluated a step-counting app for older adults on an open-source wrist-worn device (Amulet). The app includes algorithms to infer the level of physical activity and to count steps. We validated the step-counting algorithm in the lab (counting steps from a video recording, n=20) and in free-living conditions-one 2-day field study (n=6) and two 12-week field studies (using the Fitbit as ground truth, n=16). During app system development, we evaluated 4 walking patterns: normal, fast, up and down a staircase, and intermittent speed. For the field studies, we evaluated 5 different cut-off values for the algorithm, using correlation and error rate as the evaluation metrics.The step-counting algorithm performed well. In the lab study, for normal walking (ROur findings demonstrate the importance of an iterative process in algorithm development before field-based deployment. This work highlights various challenges and insights involved in developing and validating monitoring systems in real-world settings. Nonetheless, our step-counting app for older adults had good performance relative to the ground truth (a commercial Fitbit step counter). Our app could potentially be used to help improve physical activity among older adults.
- Published
- 2021
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