420 results on '"John, Harald"'
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2. The blistering warfare agent O-mustard (agent T) generates protein-adducts with human serum albumin useful for biomedical verification of exposure and forms intramolecular cross-links
3. Effects of the nerve agent VX on hiPSC-derived motor neurons
4. The phosphylated butyrylcholinesterase-derived tetrapeptide GlyGluSerAla proves exposure to organophosphorus agents with enantioselectivity
5. Disulfide-adducts with cysteine residues in human serum albumin prove exposure to malodorous mercaptans in vitro
6. Evidence of nerve agent VX exposure in rat plasma by detection of albumin-adducts in vitro and in vivo
7. Isolation of human TRPA1 channel from transfected HEK293 cells and identification of alkylation sites after sulfur mustard exposure
8. Human HepaRG liver spheroids: cold storage protocol and study on pyridinium oxime-induced hepatotoxicity in vitro
9. Highly stable peptide adducts from hard keratins as biomarkers to verify local sulfur mustard exposure of hair by high-resolution mass spectrometry
10. Poisoning by organophosphorus nerve agents and pesticides: An overview of the principle strategies and current progress of mass spectrometry-based procedures for verification
11. Alkylated albumin-derived dipeptide C(-HETE)P derivatized by propionic anhydride as a biomarker for the verification of poisoning with sulfur mustard
12. Alkylated epidermal creatine kinase as a biomarker for sulfur mustard exposure: comparison to adducts of albumin and DNA in an in vivo rat study
13. Adduct of the blistering warfare agent sesquimustard with human serum albumin and its mass spectrometric identification for biomedical verification of exposure
14. A novel exposure system generating nebulized aerosol of sulfur mustard in comparison to the standard submerse exposure
15. Sulfur mustard alkylates steroid hormones and impacts hormone function in vitro
16. Forensic evidence of sulfur mustard exposure in real cases of human poisoning by detection of diverse albumin-derived protein adducts
17. List of contributors
18. Toxicokinetic aspects of nerve agents and vesicants
19. S - and N-alkylating agents diminish the fluorescence of fluorescent dye-stained DNA
20. A mass spectrometric platform for the quantitation of sulfur mustard-induced nucleic acid adducts as mechanistically relevant biomarkers of exposure
21. Activation of the human TRPA1 channel by different alkylating sulfur and nitrogen mustards and structurally related chemotherapeutic drugs
22. Bioanalytical verification of V-type nerve agent exposure: simultaneous detection of phosphonylated tyrosines and cysteine-containing disulfide-adducts derived from human albumin
23. Fatal sarin poisoning in Syria 2013: forensic verification within an international laboratory network
24. N-Acetyl-l-cysteine inhibits sulfur mustard-induced and TRPA1-dependent calcium influx
25. Liquid Chromatography-Mass Spectrometric Analysis of Tropane Alkaloids in Mammalian Samples: Techniques and Applications
26. Human 3D liver spheroids as replacement model for animal testing: production, storage, and studies on liver toxicity
27. Phosphonylated tyrosine and lysine residues as biomarkers of local exposure of human hair to the organophosphorus nerve agents sarin and VX
28. A case report of severe pirimiphos-methyl intoxication: Clinical findings and cholinesterase status
29. Express
30. Isolation of human TRPA1 channel from transfected HEK293 cells and identification of alkylation sites after sulfur mustard exposure
31. Silibinin as a potential therapeutic for sulfur mustard injuries
32. Knowledge Acquisition and Knowledge Enablers in International Joint Ventures and their Foreign Parents
33. A role for solvents in the toxicity of agricultural organophosphorus pesticides
34. Information modelling using product life cycle views
35. EXPRESS
36. CHAPTER 7. The Impact of New Technologies on the Elucidation of Chemical Warfare Agent Toxicology
37. V-type nerve agents phosphonylate ubiquitin at biologically relevant lysine residues and induce intramolecular cyclization by an isopeptide bond
38. Stable adducts of nerve agents sarin, soman and cyclosarin with TRIS, TES and related buffer compounds—Characterization by LC-ESI-MS/MS and NMR and implications for analytical chemistry
39. Simultaneous quantification of the organophosphorus pesticides dimethoate and omethoate in porcine plasma and urine by LC–ESI-MS/MS and flow-injection-ESI-MS/MS
40. Evaluation of medical countermeasures against organophosphorus compounds: The value of experimental data and computer simulations
41. High-performance liquid-chromatographic tandem-mass spectrometric methods for atropinesterase-mediated enantioselective and chiral determination of R- and S-hyoscyamine in plasma
42. Alkylated glutamic acid and histidine derived from protein‐adducts indicate exposure to sulfur mustard in avian serum
43. Nontargeted High-Resolution Mass Spectrometric Workflow for the Detection of Butyrylcholinesterase-Derived Adducts with Organophosphorus Toxicants and Structural Characterization of Their Phosphyl Moiety after In-Source Fragmentation
44. Toxicokinetic Aspects of Nerve Agents and Vesicants
45. List of Contributors
46. Matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS) for detection and identification of albumin phosphylation by organophosphorus pesticides and G- and V-type nerve agents
47. LC-ESI MS/MS quantification of atropine and six other antimuscarinic tropane alkaloids in plasma
48. Transthyretin as a target of alkylation and a potential biomarker for sulfur mustard poisoning: Electrophoretic and mass spectrometric identification and characterization
49. Alkylation of rabbit muscle creatine kinase surface methionine residues inhibits enzyme activity in vitro
50. Evidence of sulfur mustard poisoning by detection of the albumin‐derived dipeptide biomarker C(‐HETE)P after nicotinylation
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