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2. Kernaussagen und Empfehlungen der AWMF-Leitlinie „Medizinisch klinische Diagnostik bei Schimmelpilzexposition in Innenräumen“ – Update 2023

Author

Hurraß, J., additional, Heinzow, B., additional, Walser-Reichenbach, S., additional, Aurbach, U., additional, Becker, S., additional, Bellmann, R., additional, Bergmann, K.-C., additional, Cornely, O. A., additional, Engelhart, S., additional, Fischer, G., additional, Gabrio, T., additional, Herr, C. E. W., additional, Joest, M., additional, Karagiannidis, C., additional, Klimek, L., additional, Köberle, M., additional, Kolk, A., additional, Lichtnecker, H., additional, Lob-Corzilius, T., additional, Mülleneisen, N., additional, Nowak, D., additional, Rabe, U., additional, Raulf, M., additional, Steiß, J.-O., additional, Stemler, J., additional, Steinmann, J., additional, Umpfenbach, U., additional, Valtanen, K., additional, Werchan, B., additional, Willinger, B., additional, and Wiesmüller, G. A., additional

Published
2024
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4. Hospitalisation Patterns in Interstitial Lung Disease - Data From the Exciting-ILD Registry

Author

Kreuter, M., primary, Kabitz, H.J., additional, Hagmeyer, L., additional, Hammerl, P., additional, Esselmann, A., additional, Wiederhold, C., additional, Skowasch, D., additional, Stolpe, C., additional, Joest, M., additional, Veitshans, S., additional, Höffgen, M., additional, Maqhuzu, P., additional, Schwarzkopf, L., additional, Hellmann, A., additional, Pfeifer, M., additional, Behr, J., additional, Guenther, A.U., additional, Herth, F.J., additional, Markart, P., additional, and Buschulte, K., additional

Published
2023
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6. Hospitalisierungsmuster bei interstitiellen Lungenerkrankungen – Daten aus dem EXCITING-ILD Register

Author

Buschulte, K, additional, Kabitz, H, additional, Hagmeyer, L, additional, Hammerl, P, additional, Esselmann, A, additional, Wiederhold, C, additional, Skowasch, D, additional, Stolpe, C, additional, Joest, M, additional, Veitshans, S, additional, Höffgen, M, additional, Maqhuzu, P, additional, Schwarzkopf, L, additional, Hellmann, A, additional, Pfeifer, M, additional, Behr, J, additional, Karpavicius, R, additional, Günther, A, additional, Herth, F, additional, Markart, P, additional, and Kreuter, M, additional

Published
2023
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8. Risikoabschätzung bei Patienten mit chronischen Atemwegs- und Lungenerkrankungen im Rahmen der SARS-CoV-2-Pandemie

Author

Lommatzsch, M., Rabe, K. F., Taube, C., Joest, M., Kreuter, M., Wirtz, H., Blum, T. G., Kolditz, M., Geerdes-Fenge, H., Otto-Knapp, R., Häcker, B., Schaberg, T., Ringshausen, F. C., Vogelmeier, C. F., Reinmuth, N., Reck, M., Gottlieb, J., Konstantinides, S., Meyer, F. J., Worth, H., Windisch, W., Welte, T., and Bauer, T.

Subjects
Pulmonary and Respiratory Medicine
Published
2020
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15. Characteristics and treatment regimens across ERS SHARP severe asthma registries

Author

van Bragt, JJMH, Adcock, IM, Bel, EHD, Braunstahl, G-J, ten Brinke, A, Busby, J, Canonica, GW, Cao, H, Chung, KF, Csoma, Z, Dahlen, B, Davin, E, Hansen, S, Heffler, E, Horvath, I, Korn, S, Kots, M, Kuna, P, Kwon, N, Louis, R, Plaza, V, Porsbjerg, C, Ramos-Barbon, D, Richards, LB, Skrgat, S, Sont, JK, Vijverberg, SJH, Weersink, EJM, Yasinska, V, Wagers, SS, Djukanovic, R, Maitland-van der Zee, AH, Abenhardt, B, Adler, J, Alfonso, R, Ali, R, Alkameh, S, Almonacid Sanchez, C, Alvares, L, Anderson, G, Assing, K, Ayre, S, Becker, J, Bergmann, K, Bieksiene, K, Bjerring, N, Blasi, F, Bloemen, P, Blum, H, Boeing, S, Bonavia, M, Bossios, A, Bourdin, A, Brons, A, Brusselle, G, Buis, J, Caiaffa, M, Calabrese, C, Camiciottoli, G, Caruso, C, Castilla Martinez, M, Centanni, S, Cisneros Serrano, C, Corsico, A, Cosmi, L, Costantino, M, Costello, R, Crimi, N, Dahlen, S, D'Amato, M, Davies, D, Garcia-Cosio Piqueras, FDB, Decarlo, G, Deimling, A, Del Giacco, S, Diaz Campos, R, Djandji, M, Doberer, D, Dupont, L, Dyett, K, Edelbaher, N, Edelmann, M, Ehmann, R, Ekberg-Jansson, A, Farsi, A, Favero, E, Feimer, J, Fletcher, M, Foschino, B, Frankemolle, B, Gaga, M, Gappa, M, Garcia de Pedro, J, Garcia Rivero, J, Gasplmayr, M, Gebhardt, R, Geldmacher, H, Geltner, C, Gerstlauer, M, Gibson, T, Giuseppe, G, Gogoll, C, Grimm-Sachs, V, Grisle, I, Gruen, B, Gruenewaldt, A, Guarnieri, G, Gullon Blanco, J, Hamelmann, E, Hamerlijnck, D, Hammers-Reinhard, A, Hanon, S, Harzheim, D, Heaney, L, Hellmich, S, Herden, M, Hering, T, Herth, F, Hilberg, O, Howarth, P, Hubatsch, M, Humbert, M, Husemann, K, Idzko, M, Jackson, D, Jandl, M, Jaumont, X, Joos, G, Joest, M, Juech, M, Kabesch, M, Kaiser-Labusch, P, Kardos, P, Kaessner, F, Keeley, T, Kerr, W, Kirschner, J, Klimek, L, Koca, M, Koczulla, R, Koerner-Rettberg, C, Kopac, P, Kronsbein, J, Lipinska, IK, Langer, M, Langeveld, B, Lantz, A, Lazarinis, N, Lazic, Z, Lehtimaki, L, Leuppi, J, Lombardi, C, Lommatzsch, M, Lopez-Vina, A, Luca, R, Ludviksdottir, D, Luettecke-Hecht, C, Macchia, L, Magni, T, Martinez Rivera, C, Mastoridis, P, Mazza, F, Menzella, F, Menzies-Gow, A, Michils, A, Mihaltan, F, Milanese, M, Milger-Kneidinger, K, Molinska, J, Montagna, I, Montuschi, P, Muelleneisen, N, Munoz Esquerre, M, Nanzer-Kelly, A, Nenasheva, N, Neurohr, C, Nucera, E, Otker, J, Oud, K, Paggiaro, P, Parente, R, Parkinson, J, Passalacqua, G, Patberg, N, Patella, V, Patino, O, Paulsson, T, Peche, R, Pelaia, G, Peress, E, Perez de Llano, L, Pfeffer, P, Pfister, P, Pilette, C, Pinedo Sierra, C, Pini, L, Powitz, F, Ranger, T, Rasmussen, L, Rasmussen, K, Rezelj, M, Ricciardi, L, Ricciardolo, F, Ridolo, E, Rijssenbeek-Nouwens, L, Rolla, G, Romero Ribate, D, Ruediger, S, Safioti, G, Sandstrom, T, Santus, P, Sauer, R, Schauerte, G, Schipmann, R, Schleich, F, Schmid, J, Schmidt, F, Schmidt, O, Schmitz, M, Schrag, T, Schroeer, S, Schultz, K, Schulz, C, Scichilone, N, Sedlak, V, Selb, J, Senna, G, Sergejeva, S, Serrano Pariente, J, Sichau, M, Simona, D, Singer, A, Skowasch, D, Smeenk, F, Smith, S, Solidoro, P, Spadaro, G, Spanevello, A, Stefansdottir, M, Steinmetz, K, Steiss, J, Stephan, M, Stieglitz, S, Suhling, H, Taube, C, Yavuz, ST, Tudoric, N, Ulrik, C, van de Ven, M, van den Elshout, F, Van Dyke, M, Van Nederveen-Bendien, S, van Veen, I, Vandenplas, O, Velthove, K, Vianello, A, Vogelberg, C, Wallen-Nielsen, E, Weersink, EJ, Wisskirchen, T, Yacoub, M, Yancey, S, Zappa, M, Zielen, S, Zimmermann, C, Zimmermann, R, van Bragt, JJMH, Adcock, IM, Bel, EHD, Braunstahl, G-J, ten Brinke, A, Busby, J, Canonica, GW, Cao, H, Chung, KF, Csoma, Z, Dahlen, B, Davin, E, Hansen, S, Heffler, E, Horvath, I, Korn, S, Kots, M, Kuna, P, Kwon, N, Louis, R, Plaza, V, Porsbjerg, C, Ramos-Barbon, D, Richards, LB, Skrgat, S, Sont, JK, Vijverberg, SJH, Weersink, EJM, Yasinska, V, Wagers, SS, Djukanovic, R, Maitland-van der Zee, AH, Abenhardt, B, Adler, J, Alfonso, R, Ali, R, Alkameh, S, Almonacid Sanchez, C, Alvares, L, Anderson, G, Assing, K, Ayre, S, Becker, J, Bergmann, K, Bieksiene, K, Bjerring, N, Blasi, F, Bloemen, P, Blum, H, Boeing, S, Bonavia, M, Bossios, A, Bourdin, A, Brons, A, Brusselle, G, Buis, J, Caiaffa, M, Calabrese, C, Camiciottoli, G, Caruso, C, Castilla Martinez, M, Centanni, S, Cisneros Serrano, C, Corsico, A, Cosmi, L, Costantino, M, Costello, R, Crimi, N, Dahlen, S, D'Amato, M, Davies, D, Garcia-Cosio Piqueras, FDB, Decarlo, G, Deimling, A, Del Giacco, S, Diaz Campos, R, Djandji, M, Doberer, D, Dupont, L, Dyett, K, Edelbaher, N, Edelmann, M, Ehmann, R, Ekberg-Jansson, A, Farsi, A, Favero, E, Feimer, J, Fletcher, M, Foschino, B, Frankemolle, B, Gaga, M, Gappa, M, Garcia de Pedro, J, Garcia Rivero, J, Gasplmayr, M, Gebhardt, R, Geldmacher, H, Geltner, C, Gerstlauer, M, Gibson, T, Giuseppe, G, Gogoll, C, Grimm-Sachs, V, Grisle, I, Gruen, B, Gruenewaldt, A, Guarnieri, G, Gullon Blanco, J, Hamelmann, E, Hamerlijnck, D, Hammers-Reinhard, A, Hanon, S, Harzheim, D, Heaney, L, Hellmich, S, Herden, M, Hering, T, Herth, F, Hilberg, O, Howarth, P, Hubatsch, M, Humbert, M, Husemann, K, Idzko, M, Jackson, D, Jandl, M, Jaumont, X, Joos, G, Joest, M, Juech, M, Kabesch, M, Kaiser-Labusch, P, Kardos, P, Kaessner, F, Keeley, T, Kerr, W, Kirschner, J, Klimek, L, Koca, M, Koczulla, R, Koerner-Rettberg, C, Kopac, P, Kronsbein, J, Lipinska, IK, Langer, M, Langeveld, B, Lantz, A, Lazarinis, N, Lazic, Z, Lehtimaki, L, Leuppi, J, Lombardi, C, Lommatzsch, M, Lopez-Vina, A, Luca, R, Ludviksdottir, D, Luettecke-Hecht, C, Macchia, L, Magni, T, Martinez Rivera, C, Mastoridis, P, Mazza, F, Menzella, F, Menzies-Gow, A, Michils, A, Mihaltan, F, Milanese, M, Milger-Kneidinger, K, Molinska, J, Montagna, I, Montuschi, P, Muelleneisen, N, Munoz Esquerre, M, Nanzer-Kelly, A, Nenasheva, N, Neurohr, C, Nucera, E, Otker, J, Oud, K, Paggiaro, P, Parente, R, Parkinson, J, Passalacqua, G, Patberg, N, Patella, V, Patino, O, Paulsson, T, Peche, R, Pelaia, G, Peress, E, Perez de Llano, L, Pfeffer, P, Pfister, P, Pilette, C, Pinedo Sierra, C, Pini, L, Powitz, F, Ranger, T, Rasmussen, L, Rasmussen, K, Rezelj, M, Ricciardi, L, Ricciardolo, F, Ridolo, E, Rijssenbeek-Nouwens, L, Rolla, G, Romero Ribate, D, Ruediger, S, Safioti, G, Sandstrom, T, Santus, P, Sauer, R, Schauerte, G, Schipmann, R, Schleich, F, Schmid, J, Schmidt, F, Schmidt, O, Schmitz, M, Schrag, T, Schroeer, S, Schultz, K, Schulz, C, Scichilone, N, Sedlak, V, Selb, J, Senna, G, Sergejeva, S, Serrano Pariente, J, Sichau, M, Simona, D, Singer, A, Skowasch, D, Smeenk, F, Smith, S, Solidoro, P, Spadaro, G, Spanevello, A, Stefansdottir, M, Steinmetz, K, Steiss, J, Stephan, M, Stieglitz, S, Suhling, H, Taube, C, Yavuz, ST, Tudoric, N, Ulrik, C, van de Ven, M, van den Elshout, F, Van Dyke, M, Van Nederveen-Bendien, S, van Veen, I, Vandenplas, O, Velthove, K, Vianello, A, Vogelberg, C, Wallen-Nielsen, E, Weersink, EJ, Wisskirchen, T, Yacoub, M, Yancey, S, Zappa, M, Zielen, S, Zimmermann, C, and Zimmermann, R

Abstract

Little is known about the characteristics and treatments of patients with severe asthma across Europe, but both are likely to vary. This is the first study in the European Respiratory Society Severe Heterogeneous Asthma Research collaboration, Patient-centred (SHARP) Clinical Research Collaboration and it is designed to explore these variations. Therefore, we aimed to compare characteristics of patients in European severe asthma registries and treatments before starting biologicals.This was a cross-sectional retrospective analysis of aggregated data from 11 national severe asthma registries that joined SHARP with established patient databases.Analysis of data from 3236 patients showed many differences in characteristics and lifestyle factors. Current smokers ranged from 0% (Poland and Sweden) to 9.5% (Belgium), mean body mass index ranged from 26.2 (Italy) to 30.6 kg·m-2 (the UK) and the largest difference in mean pre-bronchodilator forced expiratory volume in 1 s % predicted was 20.9% (the Netherlands versus Hungary). Before starting biologicals patients were treated differently between countries: mean inhaled corticosteroid dose ranged from 700 to 1335 µg·day-1 between those from Slovenia versus Poland when starting anti-interleukin (IL)-5 antibody and from 772 to 1344 µg·day-1 in those starting anti-IgE (Slovenia versus Spain). Maintenance oral corticosteroid use ranged from 21.0% (Belgium) to 63.0% (Sweden) and from 9.1% (Denmark) to 56.1% (the UK) in patients starting anti-IL-5 and anti-IgE, respectively.The severe asthmatic population in Europe is heterogeneous and differs in both clinical characteristics and treatment, often appearing not to comply with the current European Respiratory Society/American Thoracic Society guidelines definition of severe asthma. Treatment regimens before starting biologicals were different from inclusion criteria in clinical trials and varied between countries.

Published
2020

19. Outcome differences between idiopathic pulmonary fibrosis (IPF) and other interstitial lung diseases (ILD) – data from the EXCITING registry

Author

Kreuter, M, additional, Kabitz, HJ, additional, Hagmeyer, L, additional, Hammerl, P, additional, Esselmann, A, additional, Wiederhold, C, additional, Skowasch, D, additional, Stolpe, C, additional, Joest, M, additional, Veitshans, S, additional, Witt, S, additional, Leidl, R, additional, Hellmann, A, additional, Pfeifer, M, additional, Behr, J, additional, Kauschka, D, additional, Günther, A, additional, Herth, FJF, additional, and Markart, P, additional

Published
2019
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20. Risikoabschätzung bei Patienten mit chronischen Atemwegs- und Lungenerkrankungen im Rahmen der SARS-CoV-2-Pandemie * : Stellungnahme der Deutschen Gesellschaft für Pneumologie und Beatmungsmedizin e. V. (DGP) mit Unterstützung des Bundesverbands der Pneumologen, Schlaf- und Beatmungsmediziner e. V. (BdP)

Author

Lommatzsch, M., Rabe, K. F., Taube, C., Joest, M., Kreuter, M., Wirtz, H., Blum, T. G., Kolditz, M., Geerdes-Fenge, H., Otto-Knapp, R., Häcker, B., Schaberg, T., Ringshausen, F. C., Vogelmeier, C. F., Reinmuth, N., Reck, M., Gottlieb, J., Konstantinides, S., Meyer, F. J., and Worth, H.

Published
2021
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21. Indoor Mold: Important Considerations for Medical Advice to Patients.

Author

Hurraß, J., Nowak, D., Heinzow, B., Joest, M., Stemler, J., and Wiesmüller, G. A.

Abstract

Background: According to self-reported frequencies, every fifth or sixth dwelling in Germany is affected by dampness and/or mold. This carries a potential risk to health. Methods: This review is based on pertinent publications retrieved by a selective literature search and inquiry in the GENESIS database, on the AWMF guideline on the medical clinical diagnosis of indoor mold exposure, as updated in 2023, and on the relevant contents of other current guidelines. Based on this research, we present an algorithm for the evaluation of health problems that may be due to mold in indoor environments. Results: A rational diagnostic work-up begins with history-taking and physical examination, with attention to risk factors--above all, immune compromise and atopy. If there is evidence of atopy, targeted allergy diagnostics should be performed, consisting of a skin prick test and/or measurement of specific IgE antibodies, supplemented whenever indicated by provocative testing and cellular test systems. If the patient's immune response is compromised, the immediate cessation of mold exposure has absolute priority. Any suspected invasive fungal infection should be evaluated with radiological, microbiological, serological, and immunological testing. Indoor measurements of mold fungi, microbial volatile organic compounds (MVOC), and/or mycotoxins are generally not indicated as part of the medical evaluation; nor are blood or urine tests for particular mold components or metabolites. Conclusion: Mold in indoor environments should be dealt with by rapid exposure elimination for patients at risk, the rational diagnostic evaluation of any symptoms and signs of disease, and patient education about the possibilities and limitations of diagnostic testing and the generally limited utility of measurements in the affected interior spaces. [ABSTRACT FROM AUTHOR]

Published
2024
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25. Diagnostik und Therapie von Patienten mit interstitiellen Lungenerkrankungen in Deutschland – das EXCITING ILD Register

Author

Kreuter, M, additional, Herth, FJF, additional, Wacker, M, additional, Witt, S, additional, Kabitz, HJ, additional, Hagmeyer, L, additional, Hammerl, P, additional, Esselmann, A, additional, Wiederholf, C, additional, Skowasch, D, additional, Stolpe, C, additional, Joest, M, additional, Veitshans, S, additional, Leidl, R, additional, Hellmann, A, additional, Pfeifer, M, additional, Behr, J, additional, Kauschka, D, additional, Mall, M, additional, Günther, A, additional, and Markart, P, additional

Published
2018
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32. How to diagnose mould allergy? Comparison of skin prick tests with specific IgE results

Author

Kespohl, S., primary, Maryska, S., additional, Bünger, J., additional, Hagemeyer, O., additional, Jakob, T., additional, Joest, M., additional, Knecht, R., additional, Koschel, D., additional, Kotschy-Lang, N., additional, Merget, R., additional, Mülleneisen, N. K., additional, Rabe, U., additional, Röseler, S., additional, Sander, I., additional, Stollewerk, D., additional, Straube, H., additional, Ulmer, H. M., additional, van Kampen, V., additional, Walusiak-Skorupa, J., additional, Wiszniewska, M., additional, Wurpts, G., additional, Brüning, T., additional, and Raulf, M., additional

Published
2016
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33. A Blueprint for Constructing Peer-to-Peer Systems Robust to Dynamic Worst-Case Joins and Leaves

Author

Stefan Schmid, Joest M. Smit, Roger Wattenhofer, and Fabian Kuhn

Subjects
Degree (graph theory), Computer science, Distributed computing, Logical topology, Joins, Topology (electrical circuits), Fault tolerance, Peer-to-peer, Network topology, computer.software_genre, Binary logarithm, computer
Abstract

Until now, the analysis of fault tolerance of peer-to-peer systems usually only covers random faults of some kind. Contrary to traditional algorithmic research, faults as well as joins and leaves occurring in a worst-case manner are hardly considered. In this paper, we devise techniques to build dynamic peer-to-peer systems which remain fully functional in spite of an adversary which continuously adds and removes peers. We exemplify our algorithms on a pancake topology and present a system which maintains peer degree and network diameter O(log n/log log n), where n is the total number of peers in the system.

Published
2006
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34. Schimmelpilzallergie: Sensibilisierungshäufigkeit und Konkordanz verschiedener Hautprickteste im Vergleich zur spezifischen IgE-Bestimmung

Author

Kespohl, S, primary, Maryska, S, additional, Bünger, J, additional, Hagemeyer, O, additional, Jakob, T, additional, Joest, M, additional, Knecht, R, additional, Koschel, D, additional, Kotschy-Lang, N, additional, Merget, R, additional, Mülleneisen, NK, additional, Rabe, U, additional, Röseler, S, additional, Stollewert, D, additional, Straube, H, additional, Ulmer, HM, additional, Walusiak-Skorupa, J, additional, Wiszniewska, M, additional, Wurpts, G, additional, Brüning, T, additional, and Raulf, M, additional

Published
2015
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