1. Home-based pulmonary rehabilitation early after hospitalisation in COPD (early HomeBase): protocol for a randomised controlled trial
- Author
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Hayley Crute, Helen Boursinos, Narelle S Cox, Ajay Mahal, Cade Ringin, Mary D Santos, Aroub Lahham, Nia Luxton, Stephanie van Hilten, Elizabeth Webb, Lissa Spencer, Ling-Ling Tsai, Samantha Gavin, Claire Boote, Caitlin Le Maitre, Graham Hepworth, Heather MacDonald, Megan Byrne, Christine F McDonald, Janet Bondarenko, Renae J McNamara, Jennifer Broe, Amanda Nichols, Monique Corbett, Tunya Marceau, Joanna Melinz, Angela T Burge, Paul O'Halloran, Brooke Warrick, and Anne E Holland
- Subjects
Pulmonary and Respiratory Medicine ,medicine.medical_specialty ,Exacerbation ,medicine.medical_treatment ,Chronic Obstructive Pulmonary Disease ,Patient Readmission ,law.invention ,Diseases of the respiratory system ,Pulmonary Disease, Chronic Obstructive ,Randomized controlled trial ,law ,Intervention (counseling) ,medicine ,Humans ,Pulmonary rehabilitation ,Randomized Controlled Trials as Topic ,Protocol (science) ,COPD ,RC705-779 ,exercise ,business.industry ,Respiratory disease ,medicine.disease ,Home based ,pulmonary rehabilitation ,Exercise Therapy ,Hospitalization ,COPD exacerbations ,Physical therapy ,Quality of Life ,Medicine ,business - Abstract
IntroductionChronic obstructive pulmonary disease (COPD) is characterised by exacerbations of respiratory disease, frequently requiring hospital admission. Pulmonary rehabilitation can reduce the likelihood of future hospitalisation, but programme uptake is poor. This study aims to compare hospital readmission rates, clinical outcomes and costs between people with COPD who undertake a home-based programme of pulmonary rehabilitation commenced early (within 2 weeks) of hospital discharge with usual care.MethodsA multisite randomised controlled trial, powered for superiority, will be conducted in Australia. Eligible patients admitted to one of the participating sites for an exacerbation of COPD will be invited to participate. Participants will be randomised 1:1. Intervention group participants will undertake an 8-week programme of home-based pulmonary rehabilitation commencing within 2 weeks of hospital discharge. Control group participants will receive usual care and a weekly phone call for attention control. Outcomes will be measured by a blinded assessor at baseline, after the intervention (week 9–10 posthospital discharge), and at 12 months follow-up. The primary outcome is hospital readmission at 12 months follow-up.Ethics and disseminationHuman Research Ethics approval for all sites provided by Alfred Health (Project 51216). Findings will be published in peer-reviewed journals, conferences and lay publications.Trial registration numberACTRN12619001122145.
- Published
- 2021