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14 results on '"Jing, Wutang"'

2. Research Progress of Efficacy Biomarkers Related to Immune Checkpoint Inhibitors

Author

YANG Wenwen, TIAN Hongwei, LEI Caining, HUANG Xianbin, JING Wutang, JIN Chuanwei, SONG Shaoming, GONG Shiyi, and GUO Tiankang

Subjects
immunotherapy, immune checkpoint inhibitors, biomarkers, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282
Abstract

In recent years, immunotherapy with immune checkpoint as the target has made revolutionary breakthroughs in the treatment of a variety of advanced solid tumors. Notwithstanding the impressive long-term therapeutic benefits, their efficacy is limited to a small subset of cancer patients. Some patients experienced drug resistance and immune-related adverse events (irAEs). Immune checkpoint inhibitors (ICIs) primarily include antibodies targeting CTLA-4 and antibodies targeting PD-1 and its ligands. Thus, it is of utmost importance to screen potential biomarkers in populations that may benefit from immunotherapy, to maximize therapeutic benefits. This review summarizes the mechanism of ICIs and its related efficacy biomarker, to better guide the application of immunotherapy in clinical practice.

Published
2022
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12. Efficacy and safety of laparoscopic holmium laser lithotripsy in the treatment of complicated biliary calculus

Author

Jin, Penghui, Jing, Wutang, Zhan, Weipeng, Han, Caiwen, Si, Moubo, Yang, Jia, Li, Yiping, Gu, Yuanhui, Ma, Yuntao, and Guo, Tiankang

Subjects
Common Bile Duct, Male, biliary calculus, holmium laser, Gallstones, Lasers, Solid-State, lithotripsy, Middle Aged, Lithotripsy, Laser, laparoscopic, Treatment Outcome, Case-Control Studies, Humans, Female, Laparoscopy, Systematic Review and Meta-Analysis, Research Article, meta analysis
Abstract

Backgroud: The aim of this study was to assess the efficacy and safety of laparoscopic holmium laser lithotripsy (LHLL) in the treatment of complicated biliary calculus. Methods: We systematically searched the electronic database (PubMed, EMBASE, Cochrane library, Web of science, and Chinese Biomedical Literature Database) up to May 2018 to identify case-controlled studies that compared LHLL with laparoscopic bile duct exploration (LBDE) for complicated biliary calculus. Results: Five case-controlled studies were included, with 541 patients (273 in the LHLL group and 268 in the LBDE group). Compared with LBDE, LHLL was associated with shorter operative time (weighted mean difference [WMD] = -40.04, P

Published
2019

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