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2. Chern numbers of topological phonon band crossing determined with inelastic neutron scattering

Author

Jin, Zhendong, Hu, Biaoyan, Liu, Yiran, Li, Yangmu, Zhang, Tiantian, Iida, Kazuki, Kamazawa, Kazuya, Kolesnikov, A. I., Stone, M. B., Zhang, Xiangyu, Chen, Haiyang, Wang, Yandong, Zaliznyak, I. A., Tranquada, J. M., Fang, Chen, and Li, Yuan

Subjects
Condensed Matter - Mesoscale and Nanoscale Physics
Abstract

Topological invariants in the band structure, such as Chern numbers, are crucial for the classification of topological matters and dictate the occurrence of exotic properties, yet their direct spectroscopic determination has been largely limited to electronic bands. Here, we use inelastic neutron scattering in conjunction with ab initio calculations to identify a variety of topological phonon band crossings in MnSi and CoSi single crystals. We find a distinct relation between the Chern numbers of a band-crossing node and the scattering intensity modulation in momentum space around the node. Given sufficiently high resolution, our method can be used to determine arbitrarily large Chern numbers of topological phonon band-crossing nodes., Comment: 14 pages, 9 figures including supplemental material

Published
2022
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3. Magnetic molecular orbitals in MnSi

Author

Jin, Zhendong, Li, Yangmu, Hu, Zhigang, Hu, Biaoyan, Liu, Yiran, Iida, Kazuki, Kamazawa, Kazuya, Stone, M. B., Kolesnikov, A. I., Abernathy, D. L., Zhang, Xiangyu, Chen, Haiyang, Wang, Yandong, Fang, Chen, Wu, Biao, Zaliznyak, I. A., Tranquada, J. M., and Li, Yuan

Subjects
Condensed Matter - Strongly Correlated Electrons, Condensed Matter - Mesoscale and Nanoscale Physics, Physics - Atomic and Molecular Clusters
Abstract

A large body of knowledge about magnetism is attained from models of interacting spins, which usually reside on magnetic ions. Proposals beyond the ionic picture are uncommon and seldom verified by direct observations in conjunction with microscopic theory. Here, using inelastic neutron scattering to study the itinerant near-ferromagnet MnSi, we find that the system's fundamental magnetic units are interconnected, extended molecular orbitals consisting of three Mn atoms each, rather than individual Mn atoms. This result is further corroborated by magnetic Wannier orbitals obtained by ab initio calculations. It contrasts the ionic picture with a concrete example, and presents a novel regime of the spin waves where the wavelength is comparable to the spatial extent of the molecular orbitals. Our discovery brings important insights into not only the magnetism of MnSi, but also a broad range of magnetic quantum materials where structural symmetry, electron itinerancy and correlations act in concert., Comment: 27 pages, 27 figures including supplemental; comments are welcome

Published
2022
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6. Gastrointestinal symptoms of long COVID-19 related to the ectopic colonization of specific bacteria that move between the upper and lower alimentary tract and alterations in serum metabolites

Author

Zhang, Deyu, Weng, Siyuan, Xia, Chuanchao, Ren, Yuqing, Liu, Zaoqu, Xu, Yudi, Yang, Xiaoli, Wu, Ruhao, Peng, Lisi, Sun, Liqi, Zhu, Jiaqi, Liang, Xuesong, Jia, Yin, Wang, Huaizhou, Chen, Qian, Liu, Dongtian, Chen, Yi, Guo, Honglei, Han, Xinwei, Jin, Zhendong, Chen, Cui, Yang, Xia, Li, Zhaoshen, and Huang, Haojie

Published
2023
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16. An individualised 3D computational flow and particle model to predict the deposition of inhaled medicines:A case study using a nebuliser

Author

Wang, Yulong, Jin, Zhendong, Cui, Yan, Dong, Rongbo, Li, Lei, Lizal, Frantisek, Hriberšek, Matjaž, Ravnik, Jure, Yang, Mingshi, Liu, Yinshui, Wang, Yulong, Jin, Zhendong, Cui, Yan, Dong, Rongbo, Li, Lei, Lizal, Frantisek, Hriberšek, Matjaž, Ravnik, Jure, Yang, Mingshi, and Liu, Yinshui

Abstract

Background and objective: : Drug inhalation is generally accepted as the preferred administration method for treating respiratory diseases. To achieve effective inhaled drug delivery for an individual, it is necessary to use an interdisciplinary approach that can cope with inter-individual differences. The paper aims to present an individualised pulmonary drug deposition model based on Computational Fluid and Particle Dynamics simulations within a time frame acceptable for clinical use. Methods: We propose a model that can analyse the inhaled drug delivery efficiency based on the patient's airway geometry as well as breathing pattern, which has the potential to also serve as a tool for a sub-regional diagnosis of respiratory diseases. The particle properties and size distribution are taken for the case of drug inhalation by using nebulisers, as they are independent of the patient's breathing pattern. Finally, the inhaled drug doses that reach the deep airways of different lobe regions of the patient are studied. Results: The numerical accuracy of the proposed model is verified by comparison with experimental results. The difference in total drug deposition fractions between the simulation and experimental results is smaller than 4.44% and 1.43% for flow rates of 60 l/min and 15 l/min, respectively. A case study involving a COVID-19 patient is conducted to illustrate the potential clinical use of the model. The study analyses the drug deposition fractions in relation to the breathing pattern, aerosol size distribution, and different lobe regions. Conclusions: The entire process of the proposed model can be completed within 48 h, allowing an evaluation of the deposition of the inhaled drug in an individual patient's lung within a time frame acceptable for clinical use. Achieving a 48-hour time window for a single evaluation of patient-specific drug delivery enables the physician to monitor the patient's changing conditions and potentially adjust the drug administra

Published
2024

18. Consensus statements on endoscopic ultrasound‐guided tissue acquisition. Guidelines from the Asian Endoscopic Ultrasound Group.

Author

Chong, Charing Ching‐Ning, Pittayanon, Rapat, Pausawasdi, Nonthalee, Bhatia, Vikram, Okuno, Nozomi, Tang, Raymond Shing‐Yan, Cheng, Tsu‐Yao, Kuo, Yu‐Ting, Oh, Dongwook, Song, Tae Jun, Kim, Tae Hyeon, Hara, Kazuo, Chan, Anthony Wing‐Hung, Leung, Howard Ho Wai, Yang, Aiming, Jin, Zhendong, Xu, Can, Lakhtakia, Sundeep, Wang, Hsiu‐Po, and Seo, Dong‐Wan

Subjects
ENDOSCOPIC ultrasonography, NEEDLE biopsy, GASTROENTEROLOGISTS, PATHOLOGISTS, SURGEONS
Abstract

Objectives: This consensus was developed by the Asian EUS Group (AEG), who aimed to formulate a set of practice guidelines addressing various aspects of endoscopic ultrasound‐guided tissue acquisition (EUS‐TA). Methods: The AEG initiated the development of consensus statements and formed an expert panel comprising surgeons, gastroenterologists, and pathologists. Three online consensus meetings were conducted to consolidate the statements and votes. The statements were presented and discussed in the first two consensus meetings and revised according to comments. Final voting was conducted at a third consensus meeting. The Grading of Recommendations, Assessment, Development, and Evaluation system was adopted to define the strength of the recommendations and quality of evidence. Results: A total of 20 clinical questions and statements regarding EUS‐TA were formulated. The committee recommended that fine‐needle biopsy (FNB) needles be preferred over conventional fine‐needle aspiration (FNA) needles for EUS‐TA of subepithelial lesions. For solid pancreatic masses, rapid on‐site evaluation is not routinely recommended when FNB needles are used. For dedicated FNB needles, fork‐tip and Franseen‐tip needles have essentially equivalent performance. Conclusion: This consensus provides guidance for EUS‐TA, thereby enhancing the quality of EUS‐TA. [ABSTRACT FROM AUTHOR]

Published
2024
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26. CTM2‐2023‐06‐1111: Targeting regulatory T‐cells in pancreas during acute pancreatitis: Programmed‐death 1 blockage as a potential therapeutic for infectious pancreatic necrosis

Author

Zhang, Deyu, primary, Yin, Hua, additional, Wu, Chang, additional, Li, Shiyu, additional, Nabi, Ghulam, additional, Peng, Lisi, additional, Mao, Xiaotong, additional, Jin, Zhendong, additional, Li, Zhaoshen, additional, Su, Xiaoju, additional, and Huang, Haojie, additional

Published
2023
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34. Diagnosis by Endoscopic Ultrasonography-Guided Sampling through the Lower Gastrointestinal Tract.

Author

Wang, Jingyuan, Liu, Yue, Wu, Chang, Fan, Jiayu, Jin, Zhendong, and Wang, Kaixuan

Subjects
GASTROINTESTINAL system, ENDOSCOPIC ultrasonography, NEEDLE biopsy, SIGMOID colon, DIAGNOSIS, NEEDLESTICK injuries
Abstract

Endoscopic ultrasound-guided fine-needle aspiration/biopsy (EUS-FNA/FNB) is very safe and has a high diagnostic rate for upper gastrointestinal lesions, especially pancreatic lesions, but its application in the lower gastrointestinal tract has rarely been reported. Due to the tortuous course of the colorectum, with the sigmoid colon particularly prone to perforation, most endoscopists are reluctant to perform lateral-sector endoscopic ultrasound scanning without a water-bag protection for the puncture. The ultrasonic endoscopy and flexible puncture needle techniques recently introduced into clinical practice have made ultrasound-guided puncture safer and more convenient. In addition, endoscopists have carefully tested various protective measures to improve the safety of the lower gastrointestinal puncture, substantially increasing its clinical feasibility. In this article, we review the iterations of endoscopic ultrasound equipment introduced in recent years and the many ingenious ideas proposed by endoscopists regarding lower gastrointestinal puncture. [ABSTRACT FROM AUTHOR]

Published
2024
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42. Magnetic molecular orbitals in MnSi

Author

Jin, Zhendong, primary, Li, Yangmu, additional, Hu, Zhigang, additional, Hu, Biaoyan, additional, Liu, Yiran, additional, Iida, Kazuki, additional, Kamazawa, Kazuya, additional, Stone, Matthew B., additional, Kolesnikov, Alexander I., additional, Abernathy, Douglas L., additional, Zhang, Xiangyu, additional, Chen, Haiyang, additional, Wang, Yandong, additional, Fang, Chen, additional, Wu, Biao, additional, Zaliznyak, Igor A., additional, Tranquada, John M., additional, and Li, Yuan, additional

Published
2023
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44. A Chinese prospective multicenter cohort study evaluating EUS-guided drainage of pancreatic fluid collections using the Hot AXIOS system

Author

Sun, Siyu, primary, Zhang, Shutian, primary, Li, Peng, additional, Zhang, Zheng, additional, Wang, Sheng, additional, Jin, Zhendong, additional, Du, Yiqi, additional, Yang, Aiming, additional, Feng, Yunlu, additional, Zou, Xiaoping, additional, Wang, Lei, additional, Wang, Xiaoyan, additional, Tian, Li, additional, Zhou, Pinghong, additional, Zhang, Yiqun, additional, Liu, Jun, additional, Ding, Zhen, additional, Zhang, Junwen, additional, and Yang, Jian, additional

Published
2023
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49. Additional file 4 of Gastrointestinal symptoms of long COVID-19 related to the ectopic colonization of specific bacteria that move between the upper and lower alimentary tract and alterations in serum metabolites

Author

Zhang, Deyu, Weng, Siyuan, Xia, Chuanchao, Ren, Yuqing, Liu, Zaoqu, Xu, Yudi, Yang, Xiaoli, Wu, Ruhao, Peng, Lisi, Sun, Liqi, Zhu, Jiaqi, Liang, Xuesong, Jia, Yin, Wang, Huaizhou, Chen, Qian, Liu, Dongtian, Chen, Yi, Guo, Honglei, Han, Xinwei, Jin, Zhendong, Chen, Cui, Yang, Xia, Li, Zhaoshen, and Huang, Haojie

Abstract

Additional file 4: Table S2. Differential metabolites in serum between follow-up group and mild group.

Published
2023
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50. Additional file 2 of Gastrointestinal symptoms of long COVID-19 related to the ectopic colonization of specific bacteria that move between the upper and lower alimentary tract and alterations in serum metabolites

Author

Zhang, Deyu, Weng, Siyuan, Xia, Chuanchao, Ren, Yuqing, Liu, Zaoqu, Xu, Yudi, Yang, Xiaoli, Wu, Ruhao, Peng, Lisi, Sun, Liqi, Zhu, Jiaqi, Liang, Xuesong, Jia, Yin, Wang, Huaizhou, Chen, Qian, Liu, Dongtian, Chen, Yi, Guo, Honglei, Han, Xinwei, Jin, Zhendong, Chen, Cui, Yang, Xia, Li, Zhaoshen, and Huang, Haojie

Abstract

Additional file 2: Table S1. Clinical characteristics of the enrolled patients for serum UPLC-MS/MS-based widely targeted metabolomics.

Published
2023
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