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Given the phenomenon of "financing is difficult and expensive" for MSEs, this paper empirically investigated the influencing mechanism of the credit demand side characteristics on the financing constraints of MSEs based on the information conveyance perspective. The conclusions show that MSEs in China are severely suffering from financing constraints and 57.17% and 50.00% of MSEs with credit demand have not applied for loans from formal and informal financing channels, respectively. In terms of enterprise characteristics, MSEs have low asset size, short establishment history, weak profitability, and lack of tools such as fixed assets, complete financial management system, professional technicians, and private brands to convey risk information to financing institutions, which are key factors resulting in their financing constraints. In terms of owner characteristics, young owners lack financing experience and convey higher risk information to financing institutions; therefore, owners' age negatively influences the financing constraints of MSEs. These findings suggest that banks can use big data credit technology as a tool to obtain risk information about MSEs, and the government should implement diversified interventions to improve the information environment in financial markets. These findings provide empirical evidence for banks and governments to address the financing constraints of MSEs. [ABSTRACT FROM AUTHOR]

Aiming at the strategic behaviour in 'technology make-or-buy decisions' in the real economy, this study develops a Cournot competition model with endogenous technological level, by comparing the technology acquisition cost of technologically backward firms under different technology acquisition strategies, we theoretically analysed the 'anti-extortion' mechanism of indigenous innovation by technologically backward firms, and the relationship between indigenous innovation and technology imports is empirically tested by using the data of Chinese industrial enterprises above designated size. We show that indigenous innovation can significantly enhance a firm's bargaining power, and the technology acquisition strategy of simultaneous technology imports and indigenous innovation can not only reduce the technology imports cost but also reduce the indigenous innovation cost. Therefore, only by indigenous innovation based on technology imports, can firms enhance their market competitiveness. [ABSTRACT FROM AUTHOR]

Background: Arabidopsis pumila is native to the desert region of northwest China and it is extraordinarily well adapted to the local semi-desert saline soil, thus providing a candidate plant system for environmental adaptation and salt-tolerance gene mining. However, understanding of the salt-adaptation mechanism of this species is limited because of genomic sequences scarcity. In the present study, the transcriptome profiles of A. pumila leaf tissues treated with 250 mM NaCl for 0, 0.5, 3, 6, 12, 24 and 48 h were analyzed using a combination of second-generation sequencing (SGS) and third-generation single-molecule real-time (SMRT) sequencing. Results: Correction of SMRT long reads by SGS short reads resulted in 59,328 transcripts. We found 8075 differentially expressed genes (DEGs) between salt-stressed tissues and controls, of which 483 were transcription factors and 1157 were transport proteins. Most DEGs were activated within 6 h of salt stress and their expression stabilized after 48 h; the number of DEGs was greatest within 12 h of salt stress. Gene annotation and functional analyses revealed that expression of genes associated with the osmotic and ionic phases rapidly and coordinately changed during the continuous salt stress in this species, and salt stress-related categories were highly enriched among these DEGs, including oxidation–reduction, transmembrane transport, transcription factor activity and ion channel activity. Orphan, MYB, HB, bHLH, C3H, PHD, bZIP, ARF and NAC TFs were most enriched in DEGs; ABCB1, CLC-A, CPK30, KEA2, KUP9, NHX1, SOS1, VHA-A and VP1 TPs were extensively up-regulated in salt-stressed samples, suggesting that they play important roles in slat tolerance. Importantly, further experimental studies identified a mitogen-activated protein kinase (MAPK) gene MAPKKK18 as continuously up-regulated throughout salt stress, suggesting its crucial role in salt tolerance. The expression patterns of the salt-responsive 24 genes resulted from quantitative real-time PCR were basically consistent with their transcript abundance changes identified by RNA-Seq. Conclusion: The full-length transcripts generated in this study provide a more accurate depiction of gene transcription of A. pumila. We identified potential genes involved in salt tolerance of A. pumila. These data present a genetic resource and facilitate better understanding of salt-adaptation mechanism for ephemeral plants. [ABSTRACT FROM AUTHOR]

Ruthenium polypyridine complexes comprising sulfoxide ligands show dramatic photochromic behavior based on phototriggered S→O and O→S isomerization. Quantum yields of isomerization can be large, indicating that the excited-state bond-breaking and bond-making reactions are efficient. Ultrafast transient absorption spectroscopy reveals both adiabatic and non-adiabatic isomerization mechanisms. Incorporation of these complexes within polymer matrices leads to macroscopic bending of the polymer in an example of a direct transduction of photonic energy to mechanical energy. [ABSTRACT FROM AUTHOR]

The complex [Ru(bpy)2(bpSO)](PF6)2, where bpy is 2,2'-bipydine and bpSO is l,2-bis(phenylsulfinyl)ethane, exhibits three distinct isomers which are accessible upon metal-to-ligand charge-transfer (MLCT) irradiation. This complex and its parent, [Ru(bpy)2(bpte)](PF6)2, where bpte is 1,2-bis(phenylthio)ethane, have been synthesized and characterized by UV--visible spectroscopy, NMR, X-ray crystallography, and femtosecond transient absorption spectroscopy. A novel method of 2-color Pump-Repump-Probe spectroscopy has been employed to investigate all three isomers of the bis-sulfoxide complex This method allows for observation of the isomerization dynamics of sequential isomerizations of each sulfoxide from MLCT irradiation of the S,S-bonded complex to ultimately form the 0,0-bonded metastable complex. One-dimensional (l-D) and two-dimensional (2-D) (COSY, NOESY, and TOCSY) 'H NMR data show the thioether and ground state S,S-bonded sulfoxide complexes to be rigorously C2 symmetric and are consistent with the crystal structures. Transient absorption spectroscopy reveals that the S,S to S,0 isomerization occurs with an observed time constant of 56.8 (±7.4) ps. The S,0 to 0,0 isomerization time constant was found to be 59 (±4) ps by pump-repump-probe spectroscopy. The composite S,S- to 0,0-isomer quantum yield is 0.42. [ABSTRACT FROM AUTHOR]

Abstract: AdaBoost Learner is employed to investigate Structure–Activity Relationships of phenols based on molecular descriptors. In this paper, the performance of AdaBoost Learner is compared with support vector machine (SVM), artificial neural networks (ANNs) and K nearest neighbors (KNNs), which are the most common algorithms used for SARs analysis. AdaBoost Learner performed better than SVM, ANNs and KNNs in predicting the mechanism of toxicity of phenols based on molecular descriptors. It can be concluded that AdaBoost has a potential to improve the performance of SARs analysis. We believe that AdaBoost Learner will play an important and complementary role to the existing algorithms for the prediction of the mechanisms of toxicity based on SARs. We have developed an online web server for the prediction of ecotoxicity mechanisms of phenols, accessible at http://chemdata.shu.edu.cn/ecotoxity/. [Copyright &y& Elsevier]

Arabidopsis pumila, an annual ephemeral plant, plays important roles in preventing wind and sand erosion, water and soil conservation, and microhabitat improvement in the North of Xinjiang, China. Studies of adaptive mechanisms in harsh desert environments at the genetic and genomic levels can be used to more effectively develop and protect this species. The quantitative real-time polymerase chain reaction (qRT-PCR) method is one of the essential means to achieve these goals, and the selection of an appropriate reference gene is the prerequisite for qRT-PCR. In this study, 10 candidate reference genes were identified from the full-length transcriptome data of A. pumila, and their expression stabilities under four abiotic stresses (drought, heat, cold and salt) and in seven different tissues (roots, hypocotyl, cotyledon, leaves, stems, flowers and siliques) were evaluated with four programmes geNorm, NormFinder, Bestkeeper and RefFinder. Although the most stable reference genes were variable under different treatments using different software, comprehensive ranking revealed that UEP and HAF1 under drought stress, UBQ9 and GAPDH under heat stress, UBC35 and GAPDH under cold stress, GAPDH and ACT1 under salt stress, and ACT1 and GAPDH in different tissues were the most stable reference genes. Moreover, GAPDH and UBQ9 were the most suitable reference gene combinations for all samples. The expression pattern of the K+ uptake permease gene KUP9 further validated that the selected reference genes were suitable for normalization of gene expression. The identification of reliable reference genes guarantees more accurate qRT-PCR quantification for A. pumila and facilitates functional genomics studies of ephemeral plants. [ABSTRACT FROM AUTHOR]