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Your search keyword '"Jin, Suqin"' showing total 21 results
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21 results on '"Jin, Suqin"'

1. Painful Diabetic Peripheral Neuropathy Study of Chinese Outpatients (PDNSCOPE): A Multicentre Cross-Sectional Registry Study of Clinical Characteristics and Treatment in Mainland China

Author

Zhang, Yuanjin, Zhang, Shaowei, Pan, Liya, Wang, Baojun, Sun, Yuanlin, Gao, Lijun, Wang, Ling, Cui, Lijuan, Zhang, Qing, Shang, Heng, Jin, Suqin, Qin, Xing, Geng, Deqin, Yu, Xiaorong, Yang, Lin, Li, Li, Li, Zuoxiao, Yan, Chaoli, Sun, Hongbin, Sun, Tao, Du, Baoxin, Cao, Junying, Hu, Fengyun, Ma, Jianhua, Zhou, Shengnian, Zhao, Fengli, Li, Wei, Zheng, Jianming, Yi, Yanhui, Xu, Jianguo, Hu, Bo, Sheng, Baoying, Li, Zhaohui, Zhao, Zhong, Yang, Ting, Wang, Ni, Zhao, Hongdong, Mima, Dunzhu, Qu, Huaiqian, Wang, Yi, Song, Fuxia, Li, Xinyi, Li, Nan, and Fan, Dongsheng

Published
2021
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14. Activation of Mitochondrial Unfolded Protein Response in SHSY5Y Expressing APP Cells and APP/PS1 Mice

Author

Shen, Yang, primary, Ding, Mao, additional, Xie, Zhaohong, additional, Liu, Xiangtian, additional, Yang, Hui, additional, Jin, Suqin, additional, Xu, Shunliang, additional, Zhu, Zhengyu, additional, Wang, Yun, additional, Wang, Dewei, additional, Xu, Linlin, additional, Zhou, Xiaoyan, additional, Wang, Ping, additional, and Bi, Jianzhong, additional

Published
2020
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15. Underwater image restoration based on perceptually optimized generative adversarial network

Author

Jin Suqin, Chen Haixiu, Xu Weihua, and Wang Peng

Subjects
Ground truth, Image quality, Computer science, Underwater vision, business.industry, ComputingMethodologies_IMAGEPROCESSINGANDCOMPUTERVISION, Colorfulness, Image processing, 02 engineering and technology, Atomic and Molecular Physics, and Optics, Computer Science Applications, 0202 electrical engineering, electronic engineering, information engineering, RGB color model, 020201 artificial intelligence & image processing, Computer vision, Artificial intelligence, Electrical and Electronic Engineering, Underwater, business, Image restoration, ComputingMethodologies_COMPUTERGRAPHICS
Abstract

Underwater images are degraded due to the complexity of the underwater environment and medium scattering and absorption. The image degeneration includes low contrast, color distortion, and blur, which makes the task of underwater vision difficult. A perceptually optimized cycle consistency generative adversarial network (CycleGAN-VGG) is proposed to restore distorted underwater images. We adopt the framework of CycleGAN so that our method does not require pairs of distorted underwater images and corresponding ground truth images for training. Inspired by perceptual loss, we use a combination of perceptual loss, cycle-consistent loss, and adversarial loss. The multiterm loss functions guarantee that the output has the same content and structure as the input while color looks like ground truth images. In an objective assessment, our method is significantly higher than other methods in terms of colorfulness metrics and contrast metrics. It confirms that our method effectively restores the color of underwater scenes and enhances some image details and shows a superior performance when compared to other state-of-the-art methods.

Published
2020

16. Vascular endothelial growth factor alleviates mitochondrial dysfunction and suppression of mitochondrial biogenesis in models of Alzheimer's disease.

Author

Liu, Xiangtian, Chu, Bingcong, Jin, Suqin, Li, Maoyu, Xu, Yingying, Yang, Hui, Feng, Zhe, Bi, Jianzhong, and Wang, Ping

Subjects
VASCULAR endothelial growth factors, ALZHEIMER'S disease, MITOCHONDRIAL DNA, MITOCHONDRIA, CELL survival
Abstract

Mitochondrial dysfunction is a prominent feature of Alzheimer's disease (AD). As vascular endothelial growth factor (VEGF) has been shown to be protective in AD, the aim of this study was to investigate the effects of VEGF on mitochondrial function in models of AD. Adeno associated virus (AAV)-VEGF was injected into the hippocampus of APP/PS1 mice. Cognitive function was assessed in these mice with use of the Morris water maze (MWM) and β-amyloid (Aβ) levels in the hippocampus were also measured. Cell viability and reactive oxygen species (ROS) levels were determined in the SH-SY5Y cells treated with Aβ25–35 which served as a cell model of AD. Transmission electron microscopy (TEM) was used to evaluate structural changes in mitochondria and mitochondrial DNA (mtDNA) copy number and mitochondrial membrane potential (MMP) were also recorded. Finally, we investigated the effects of VEGF upon mitochondrial biogenesis, autophagy and mitochondrial autophagy (mitophagy) as determined both in vivo and in vitro with western blots. VEGF treated mice showed improvements in spatial learning and memory along with reduced Aβ levels. VEGF protected SH-SY5Y cells against Aβ25–35 induced neurotoxicity as demonstrated by increased cell viability and decreased ROS production. Associated with these effects were improvements in mitochondrial structure and function, and increased numbers of mitochondria resulting from stimulation of mitochondrial biogenesis. VEGF alleviates Aβ related patholoy in models of AD. In part, these beneficial effects of VEGF result from protection of mitochondria and stimulation of mitochondrial biogenesis. [ABSTRACT FROM AUTHOR]

Published
2021
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