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Paroxysmal sympathetic hyperactivity (PSH) is a syndrome of excessive sympathetic activity, mainly occurring in severe traumatic brain injury. However, few studies have reported the frequency of PSH and its related risk factors in adult patients with brain injury.We performed this systematic review and meta-analysis to estimate the combined incidence of PSH and the associated risk factors in adult patients with brain injury. This study was registered with the PROSPERO international prospective register of systematic reviews (https://www.crd.york. ac.uk/PROSPERO/Identifier: CRD 42021260493), and a systematic search was conducted of the scientific databases Embase, PubMed, Web of Science, Cochrane Library, and Google Scholar. All identified observational studies regarding the incidence and risk factors of PSH in adult patients with brain injury were included. Two authors extracted data independently; data were analyzed by STATA version 16.The search yielded 9 studies involving 1643 adult patients. PSH was detected in 438 patients. The combined incidence of PSH in adult patients with brain injury was 27.4% (95% confidence interval [CI], 0.190-0.358). The risk factors include patients' age (SMD = -0.592; IPSH occurs in nearly a quarter of adult patients with brain injury. Patient's age, traffic accident, admission Glasgow Coma Scale score, hydrocephalus, and diffuse axonal injury were risk factors for PSH in adult patients with brain injury. These findings may contribute to novel strategies for early diagnosis and interventions that aid in the rehabilitation of patients with brain injury.

This repository contains the datasets and results of the joint inversion-based Vp/Vs model consistency constrained double difference seismic tomography carried out for the manuscript titled “The shallowest M>6.0 induced earthquake: A coincidental product of favorably aligned triggering ingredients.” Included are the following: catalog earthquake information (CX_event.dat), relocated events after inversion (CX_tomoDDMC.reloc), inverted Vp model (CX_Vpmodel.dat), inverted Vs model (CX_Vsmodel.dat) and inverted Vp/Vs model (CX_VpVsmodel.dat). The datasets presented in this article are not readily available because we do not have the right to release the waveform data from the regional stations, which have to go through the China Earthquake Administration (CEA) authority. Requests to access the passive seismic data from our local stations should be directed to the corresponding author. TomoDD has been released by the authors through workshops and will soon be available through a repository.&nbsp

With the rapid development of computer networks, the network architecture has been more and more complex and diverse. Smart grid is a kind of wireless sensor network consuming energy in smart city. Smart grid communications have developed rapidly in recent years, while the privacy, integrity and confidentiality of user data have been the main security issues. However, lattice-based homomorphic cryptography can resist quantum attacks and effectively provide the security of the scheme. In this paper, we proposed an aggregate signature scheme based on new Batch RSA. After that, a data aggregation scheme is proposed based on this aggregate signature scheme and the qualified homomorphic cryptosystem. Compared with the previous schemes, our scheme is more secure because we implement seven properties, such as post quantum, privacy and so on. Compared with the representative scheme proposed by Abdallah et al., our scheme has lower computation and communication overhead. In addition, the cryptographic algorithms involved in our scheme are lightweight. The network model in our scheme is suitable for large intelligent communities. So our scheme is very suitable for residential area network.

In this paper, a new type of Vivaldi antenna with heat dissipation enhancement is proposed and manufactured based on three-dimensional (3-D) printing and printed circuit board (PCB) technologies. A longitudinal slot on substrate integrated waveguide (SIW) is employed to feed Vivaldi radiation structure, which replaces the balun structure of traditional Vivaldi antennas. The measured 10-dB bandwidth of antenna element reaches up to 34.48% (21.77-30.39 GHz) and the in-band realized boresight gain is 6.5-8.8 dBi. The 1×4 Vivaldi antenna array with 28.72% (21.63-28.81 GHz) bandwidth and a gain range of 10.5-12.5 dBi is achieved. The fin-shaped structure of the antenna array further enhances the heat dissipation while increasing the gain up to the range of 13.4-15.5 dBi. The measured results are in good agreement with the simulated ones. The proposed antenna array has important application potential in 5G millimeter-wave systems.

Zhejiang Province has been committed to the planning reform since the mid-1990s to adapt to economic and social transformation, urbanization and reform of administration system. The province has explored such comprehensive planning as urban system planning, integrated urban-rural planning, overall planning of county/city administrative area, and “multi-plan integration” planning in tandem. The efforts of Zhejiang have become one of the critical sources for developing our territorial spatial planning system after the government institutional reform. In the current practices of territorial spatial planning, Zhejiang has pursued further innovative exploration on optimizing urban-rural pattern, improving spatial quality, promoting spatial management and control, strengthening cross-border coordination, and developing intelligent planning in light of its foundations. By reviewing the history of Zhejiang’s comprehensive planning, the paper summarizes the overall development trend and related experiences in planning to provide insights and topics for further discussion for our current across-the-board territorial spatial planning.

This study aimed to develop transcutaneous electrical acupoint stimulation combined with an integrated perioperative nursing program and evaluate its effects on preventing subsyndromal delirium (SSD) and postoperative delirium (POD) in older patients after joint replacement surgery.Participants were randomly divided into two groups, the experimental group (n = 48) was given transcutaneous electrical acupoint stimulation combined with an integrated perioperative nursing program based on the routine care of the control group (n = 49). The incidence of SSD and POD in a week after surgery was recorded. Assessments of delirium severity, cognition, anxiety, and depression were also conducted at baseline and on postoperative day 7.The findings indicate that the intervention program had significant advances in alleviating the severity of delirium, cognitive impairment, anxiety, and depression but failed to reduce the incidence of SSD and POD.Our study indicated that TEAS combined with an integrated perioperative nursing program has a beneficial effect on alleviating symptoms of delirium, cognitive dysfunction, anxiety, and depression in older adults after joint replacement surgery.

In this letter, a compact microstrip comb array antenna with high sidelobe suppression is presented for a 24 GHz radar sensor. Based on the printed circuit board process, several series-fed microstrip comb lines are designed on the substrate to form linear antenna arrays. Chebyshev distribution is adopted for the nonuniform excitation of each antenna element to achieve a very low sidelobe level (SLL). The excitation amplitude is adjusted by tuning the feedline width between the adjacent elements. Under such circumstances, a slimmer array with a tapering distribution is realized. The proposed linear comb array consists of eight elements and is further extended to 8 × 2 and 8 × 8 planar arrays to meet different requirements. The proposed antenna arrays are verified by the simulation and measurement, which are in good agreement. The measured SLLs are better than −28 dB. The measured gains of 8 × 1, 8 × 2, and 8 × 8 comb arrays at 24.125 GHz are 12.2, 15.0, and 19.8 dBi, respectively. The return losses are better than 10 dB and the broadside gains remain stable within the regulated industrial scientific medical band from 24 to 24.25 GHz.

SUMMARYFasting is known to improve health, but the precisely beneficial effects of specific types of fasting and their underlying mechanisms are not fully understood. We herein report that in humans, occasional short-term intensive fasting (STIF), a traditional fasting format favored by Asians, promotes erythropoiesis and boosts the function of red blood cells (RBCs) in oxygen transportation, ATP generation, antioxidant capacity, and innate immune response. The rejuvenation of erythropoiesis is more pronounced in humans with low RBC counts. Using mouse models and a human erythroid progenitor cell model, we found that occasional STIF rejuvenates erythropoiesis by enhancing megakaryocyte-erythroid progenitor selfrenewal and erythroid-biased differentiation without compromising normal hematopoiesis. Molecularly, STIF relies on an autophagy-dependent but erythropoietin (EPO) upregulation-independent MS4A3-CDK2 module to augment the production of RBCs. Our findings thus suggest that STIF can occasionally be practiced as an efficient noninvasive intervention for better erythropoiesis, particularly for adults with low RBC counts.Graphical abstractIn briefXu et al showed that short-term intensive fasting (STIF), when occasionally practiced, boosts red blood cell function and promotes erythropoiesis by regulating MS4A3-CDK2 module to enhance megakaryocyte-erythroid progenitor selfrenewal and erythroid-biased differentiation.HighlightsOccasional STIF boosts the function of red blood cellsOccasional STIF promotes erythropoiesis, which is more significant in adults with low red blood cell countsOccasional STIF selectively enhances MEP selfrenewal and erythroid-biased differentiation via MS4A3-CDK2 moduleThe erythropoietic MS4A3-CDK2 response to STIF is autophagy-dependent but EPO upregulation-independent.

It is a challenging issue in smart grid to provide flexible and efficient data aggregation and at the same time maintain data integrity and data privacy. To address this issue, we firstly propose a lightweight $t$ -times homomorphic encryption scheme, which can reduce the computational cost of smart devices further and resist quantum attacks. Based on it, we propose two efficient data aggregation schemes for two application scenarios. The first scheme is suitable for small network, such as home network and small-office network. The second scheme is appropriate for medium-size network, such as a part of smart city. More specifically, we explore how the number of smart devices and the number of home area networks affect the overhead of communication and computation. The experiment results show that the proposed schemes are efficient. Moreover, the proposed schemes not only meet security requirements of integrity, confidentiality, authenticity, resistance to intermediate attack, resistance to replay attack, forward and backward security and resistance to quantum attack, but also reduce the overhead of communication and computation.

This repository contains the datasets and results of the joint inversion-based Vp/Vs model consistency constrained double difference seismic tomography carried out for the manuscript titled “Tomographic evidences for fluid induced mechanism of the extremely shallow 2019 Ms6.0 Changning earthquake, Sichuan basin.” Included are the following: catalog earthquake information (CX_event.dat), relocated events after inversion (CX_tomoDDMC.reloc), inverted Vp model (CX_Vpmodel.dat), inverted Vs model (CX_Vsmodel.dat) and inverted Vp/Vs model (CX_VpVsmodel.dat). Please consult the manual for tomoDD by Zhang and Thurber (2003) for detailed formats of these files.

In this communication, a novel fin-shaped heatsink antenna array is designed and fabricated by 3-D printing and low-temperature cofired ceramic (LTCC) technologies. Its structure consists of 16 rectangular air cavities in the bottom base, which are used to form the open-ended rectangular waveguide antennas. Combined with the waveguide and metallic fins, a step-profiled horn is formed as the antenna element, which further enhances the radiation performance. This heatsink antenna array is soldered on an LTCC substrate and the feeding network is realized by the substrate integrated waveguides (SIWs) with numerous metallic vias. These metallic vias inherently provide an effective path for transferring the heat from chips to the heatsink. The simulated performance of this heatsink antenna array is in good agreement with the measured one. The measured broadside gain is 18.1 dBi at 60 GHz, and the 10 dB relative impedance bandwidth is 11.7%.

Helium helicon wave plasma (He-HWP) wall conditioning was performed with a specially designed antenna system on the Experimental Advanced Superconducting Tokamak (EAST) under strong magnetic field (0.5–1 T). The maximum effective RF power $P_{\mathrm {eff}}$ was 30 kW at 27 MHz, and the He pressure was fixed at ~0.27 Pa. Charge-coupled device (CCD) images indicated that toroidal homogeneous but poloidal inhomogeneous He-HWPs were obtained. An obvious desorption of H2 and HD was found during He-HWP operation. Deuterium was desorbed mainly in the form of HD, with a removal rate of ~1021–1022D atoms/h. Additionally, the residual gas analyzer (RGA) results also showed a steep rise in H/D desorption during mode transition (inductively coupled plasma (ICP) $\to $ HWP) with increased $P_{\mathrm {eff}}$ from 5 to 15 kW, then a slight decline in the HWP mode with relatively higher $P_{\mathrm {eff}}$ (>15 kW), which was further verified by the spectral data of hydrogen Balmer series ( $\text{H}_{\alpha }$ and $\text{D}_{\alpha }$ ).

Diamond-like carbon (DLC) films were grown on Si substrates by high-density helicon wave plasma (HWP) generated under low pressure, with the help of CH4 as an important single-source precursor. The influence of magnetic field ( ${B}_{0}$ : 1200–2400 Gs) on the film structure, morphology, composition, and mechanical properties has been studied. The high deposition rate of the films exhibits a maximum of 800 nm/min, which is contributed by the high-density plasma generation of HWP. By the X-ray photoelectron spectroscopy (XPS) analysis, the as-deposited DLC film is composed mainly of sp2 C-C. The DLC film deposited at ${B}_{0} =2400$ Gs exhibits that the friction coefficient reaches its minimum value of $5 \times 10^{-3}$ , with small surface roughness (root mean square (RMS) ~ 10 nm). Considering that ${B}_{0}$ can be easily controlled, this article opens up a new approach to achieve ultralow friction coefficient DLC films with a high deposited rate at room temperature.

In order to handle semi-supervised clustering scenarios where only part of the pairwise constraint information is available in the target dataset, on the basis of nonnegative matrix factorization (NMF) architecture, this paper proposes a nonnegative matrix factorization-based clustering algorithm using joint regularization of manifold learning and pairwise constraints (NMF-JRMLPC) by learning given pairwise constraint knowledge and using manifold regularization theory. On the one hand, graph Laplacian is introduced to depict the manifold structure information contained in a large number of unlabeled samples, and on the other hand, the must-link or cannot-link pair-constraint rules among known samples are integrated into the target optimization design, which greatly improves the clustering performance of the algorithm. In addition, the [l2,1] norm based loss function design also helps to optimize the robustness of NMF-JRMLPC. Experimental results on eight real datasets confirm the validity of the proposed method.

Some industrial activities, such as underground mining, hydraulic fracturing (HF), can cause microearthquakes and even damaging earthquakes. In recent years, with the rapid development of mining and HF, many induced damaging earthquakes have been reported and studied. The seismic waves contain rich information of the seismic sources and wave propagation path, which are the valuable data for studying the natural and induced earthquakes. Therefore, the non-linear and time–frequency characteristics of different seismic waveforms are studied by using multifractal theory and the Hilbert–Huang transform method. In general, for both the natural and induced earthquakes, the larger the magnitude is, the longer the duration of the waveform is, and the lower the frequency is. In addition, the amplitude and frequency of natural and induced seismic wave show non-linear decreasing trend with the increase in propagation distance. Both the natural and induced earthquakes’ waveforms show clear multifractal features. The multifractal parameters Δα and Δf(α) can be used as indicators to reflect the non-linear characteristics of the seismic waveforms. The seismic waveforms’ multifractal and time–frequency characteristics recorded by the specific sensors are affected by not only the magnitudes, types and rupture mechanism of seismic sources, but also the distances from sensors to seismic sources, wave propagation path and the sensors' properties. Because the coal is soft and unconsolidated rock with developed joints and fractures, the seismic waveforms induced by mining are more complex and variable than the ones with the same magnitude induced by HF of shale and hot dry rock.

Previous studies have shown that long‐term light or moderate fasting such as intermittent fasting can improve health and prolong lifespan. However, in humans short‐term intensive fasting, a complete water‐only fasting has little been studied. Here, we used multi‐omics tools to evaluate the impact of short‐term intensive fasting on immune function by comparison of the CD45+ leukocytes from the fasting subjects before and after 72‐h fasting. Transcriptomic and proteomic profiling of CD45+ leukocytes revealed extensive expression changes, marked by higher gene upregulation than downregulation after fasting. Functional enrichment of differentially expressed genes and proteins exposed several pathways critical to metabolic and immune cell functions. Specifically, short‐term intensive fasting enhanced autophagy levels through upregulation of key members involved in the upstream signals and within the autophagy machinery, whereas apoptosis was reduced by down‐turning of apoptotic gene expression, thereby increasing the leukocyte viability. When focusing on specific leukocyte populations, peripheral neutrophils are noticeably increased by short‐term intensive fasting. Finally, proteomic analysis of leukocytes showed that short‐term intensive fasting not only increased neutrophil degranulation, but also increased cytokine secretion. Our results suggest that short‐term intensive fasting boost immune function, in particular innate immune function, at least in part by remodeling leukocytes expression profile., Short‐term intensive fasting remodels innate immunity in humans through improving neutrophil function with elevated secretion of cytokines, together with upregulation of autophagy and downregulation of apoptosis.

Microseismic monitoring systems have been widely installed to monitor potential water hazards in limestone of the coal floor. The temporal and spatial distribution of rock fracture-induced microseismic events can be used as early warning indicators of potential water inrush from the coal floor. We established a microseismic monitoring system in the working face of Wangjialing coal mine. Besides traditional fluid-independent rock fracture-induced microseismic waveforms, fluid-dependent hybrid-frequency microseismic waveforms also play important roles in determining the microseismic precursors of water inrush. Hybrid-frequency microseismic waveforms have a sharp P wave and no obvious S wave phase. We infer that the first high-frequency signal is caused by the brittleness of the rock in the floor under the influence of the water pressure. The second low-frequency signal is caused by the water oscillations in the fractures. These hybrid-frequency waveforms represent the development of fracturing. In addition, the lifting height of the complete aquiclude above the confined water is very limited, and the water inrush from the floor is often closely related to these hidden faults. Therefore, the activation signal of hidden faults in the working face of coal mining can be monitored to effectively warn about the water inrush from the coal seam floor caused by faults. By analyzing different microseismic events, the monitoring and early warning of water disaster in the coal mine floor can be improved. This will help in taking measures in advance within the mine to ensure personnel safety and to reduce property losses.

In this study, silk fabrics were treated with Atmospheric Pressure Glow Discharge (APGD) plasma in the air at a discharge voltage of 35 kV and frequency of 20 kHz. C.I. (Color Index) Natural Yellow...

With the development of smart grids and the continuous penetration of new energy power generation, the scale of the power grid has increased, and the structure and operation methods have become increasingly complex. In order to more accurately grasp the operating status of the power grid, it is necessary to estimate the operating status of the power system. In recent years, with the development of artificial intelligence and data mining technology, neural networks have also been widely used in the field of state estimation. However, there are few researches on artificial intelligence algorithms in active distribution network state estimation, and the small amount of data in the bad data detection link that needs to be carried out before state estimation also limits the application of many artificial intelligence algorithms that require a large number of training samples. A small sample learning method applied to the detection of bad data for power system state estimation is proposed, which successfully solves the problem of the lack of available training data in building a neural network model for bad data detection, and solves the traditional method calculation speed brought by the massive increase of grid data. The problem of serious decline, and the accuracy of the traditional state estimation method is improved by more than 47%.

Under the background of the "Internet+" era, enterprise management and production are faced with transformative intelligent transformation, which deeply affects the financial management work and puts forward higher requirements for information security technology. Based on multi-party security computing technology, this paper designs a cooperative computing scheme based on small-scale homomorphic encryption on multi-party security data platform, and innovates the operation mode of financial sharing. The overall design of operational financial management is constructed from multi-dimensional considerations in order to provide a useful reference for the digital transformation of enterprise financial intelligence.

Autophagy suppresses mitochondrial metabolism to preserve hematopoietic stem cells (HSCs) in mice. However, the mechanism by which autophagy regulates hematopoietic aging, in particular in humans, has largely been unexplored. Here, we demonstrate that reduction of autophagy in both hematopoietic cells and their stem cells is associated with aged hematopoiesis in human population. Mechanistically, autophagy delays hematopoietic aging by activating the downstream expression of Sirt3, a key mitochondrial protein capable of rejuvenating blood. Sirt3 is the most abundant Sirtuin family member in HSC‐enriched population, though it declines as the capacity for autophagy deteriorates with aging. Activation of autophagy upregulates Sirt3 in wild‐type mice, whereas in autophagy‐defective mice, Sirt3 expression is crippled in the entire hematopoietic hierarchy, but forced expression of Sirt3 in HSC‐enriched cells reduces oxidative stress and prevents accelerated hematopoietic aging from autophagy defect. Importantly, the upregulation of Sirt3 by manipulation of autophagy is validated in human HSC‐enriched cells. Thus, our results identify an autophagy‐Sirt3 axis in regulating hematopoietic aging and suggest a possible interventional solution to human blood rejuvenation via activation of the axis., Autophagy collaborates with Sirt3, to form a regulatory axis that synergistically delays hematopoietic aging in both mice and humans. Positive intervention to the autophagy‐Sirt3 axis leads to blood rejuvenation.