63 results on '"Jiao-Jiao Liu"'
Search Results
2. The default mode network is affected in the early stage of simian immunodeficiency virus infection: a longitudinal study
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Zhen-Chao Tang, Jiao-Jiao Liu, Xue-Tong Ding, Dan Liu, Hong-Wei Qiao, Xiao-Jie Huang, Hui Zhang, Jie Tian, and Hong-Jun Li
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acquired immune deficiency syndrome ,analysis of variance ,antiretroviral therapy ,default mode network ,functional magnetic resonance imaging ,human immunodeficiency virus ,longitudinal study ,rhesus monkeys ,simian immunodeficiency virus ,siv-mac239 ,Neurology. Diseases of the nervous system ,RC346-429 - Abstract
Acquired immune deficiency syndrome infection can lead to cognitive dysfunction represented by changes in the default mode network. Most recent studies have been cross-sectional and thus have not revealed dynamic changes in the default mode network following acquired immune deficiency syndrome infection and antiretroviral therapy. Specifically, when brain imaging data at only one time point are analyzed, determining the duration at which the default mode network is the most effective following antiretroviral therapy after the occurrence of acquired immune deficiency syndrome. However, because infection times and other factors are often uncertain, longitudinal studies cannot be conducted directly in the clinic. Therefore, in this study, we performed a longitudinal study on the dynamic changes in the default mode network over time in a rhesus monkey model of simian immunodeficiency virus infection. We found marked changes in default mode network connectivity in 11 pairs of regions of interest at baseline and 10 days and 4 weeks after virus inoculation. Significant interactions between treatment and time were observed in the default mode network connectivity of regions of interest pairs area 31/V6.R and area 8/frontal eye field (FEF). L, area 8/FEF.L and caudal temporal parietal occipital area (TPOC).R, and area 31/V6.R and TPOC.L. ART administered 4 weeks after infection not only interrupted the progress of simian immunodeficiency virus infection but also preserved brain function to a large extent. These findings suggest that the default mode network is affected in the early stage of simian immunodeficiency virus infection and that it may serve as a potential biomarker for early changes in brain function and an objective indicator for making early clinical intervention decisions.
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- 2023
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3. Early prediction of putamen imaging features in HIV-associated neurocognitive impairment syndrome
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Yu Qi, Man Xu, Wei Wang, Yuan-Yuan Wang, Jiao-Jiao Liu, Hai-Xia Ren, Ming-Ming Liu, Rui-Li Li, and Hong-Jun Li
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HIV ,Asymptomatic neurocognitive impairment ,Putamen ,Radiomics ,Neurology. Diseases of the nervous system ,RC346-429 - Abstract
Abstract Background To explore the correlation between the volume of putamen and brain cognitive impairment in patients with HIV and to predict the feasibility of early-stage HIV brain cognitive impairment through radiomics. Method Retrospective selection of 90 patients with HIV infection, including 36 asymptomatic neurocognitive impairment (ANI) patients and 54 pre-clinical ANI patients in Beijing YouAn Hospital. All patients received comprehensive neuropsychological assessment and MRI scanning. 3D Slicer software was used to acquire volume of interest (VOI) and radiomics features. Clinical variables and volume of putamen were compared between patients with ANI and pre-clinical ANI. The Kruskal Wallis test was used to analysis multiple comparisons between groups. The relationship between cognitive scores and VOI was compared using linear regression. For radiomics, principal component analysis (PCA) was used to reduce model overfitting and calculations and then a support vector machine (SVM) was used to build a binary classification model. For model performance evaluation, we used an accuracy, sensitivity, specificity and receiver operating characteristic curve (ROC). Result There were no significant differences in clinical variables between ANI group and pre-clinical-ANI group (P>0.05). The volume of bilateral putamen was significantly different between AHI group and pre-clinical group (P
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- 2021
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4. Application of Gd-EOB-DTPA-enhanced magnetic resonance imaging (MRI) in hepatocellular carcinoma
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Xue-Qin Li, Xing Wang, Da-Wei Zhao, Jun Sun, Jiao-Jiao Liu, Dong-Dong Lin, Guang Yang, Hui Liu, Zhen-Ying Xia, Cui-Yu Jia, and Hong-Jun Li
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Magnetic resonance imaging ,Gd-EOB-DTPA ,Hepatocellular carcinoma ,Surgery ,RD1-811 ,Neoplasms. Tumors. Oncology. Including cancer and carcinogens ,RC254-282 - Abstract
Abstract Background Hepatocellular carcinoma (HCC) is the most common malignant tumor of the liver, and its morbidity and mortality have been increasing in recent years. The early diagnosis and prompt treatment of small HCC are crucial to improve the prognosis and quality of life of patients. In China, hepatitis B virus infection is the main cause. HCC with a single tumor nodule of ≤ 3 cm in diameter, or HCC with a number of nodules, in which each nodule is ≤ 2 cm in diameter, with a total diameter of ≤ 3 cm, is considered as small HCC. The MRI liver-specific contrast agent can detect small HCC at the early stage. This has important clinical implications for improving the survival rate of patients. Main body Gd-EOB-DTPA-enhanced MRI can significantly improve the sensitivity and specificity of the detection of HBV-related small hepatocellular carcinoma, providing an important basis for the clinical selection of appropriate personalized treatment. Gd-EOB-DTPA-enhanced MRI can reflect the degree of HCC differentiation, and the evaluation of HCC on Gd-EOB-DTPA-enhanced MRI would be helpful for the selection of the treatment and prognosis of HCC patients. The present study reviews the progress of the application of Gd-EOB-DTPA in the early diagnosis of small HCC, its clinical treatment, the prediction of the degree of differentiation, and the assessment of recurrence and prognosis of HCC, including the pharmacoeconomics and application limitations of Gd-EOB-DTPA. The value of the application of HCC with the Gd-EOB-DTPA was summarized to provide information for improving the quality of life and prolonging the survival of patients. Conclusion Gd-EOB-DTPA-enhanced MRI has the diagnostic capability for small HCC with a diameter of ≤ 2 cm. This will have a broader application prospect in the early diagnosis of small liver cancer with a diameter of ≤ 1 cm in the future. The relationship between GD-EOB-DTPA-MRI and the degree of HCC differentiation has a large research space, and Gd-EOB-DTPA is expected to become a potential tool for the preoperative prediction and postoperative evaluation of HCC, which would be beneficial for more appropriate treatments for HCC patients.
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- 2020
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5. Per- and perfluoroalkyl substances alternatives, mixtures and liver function in adults: A community-based population study in China
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Jiao-Jiao Liu, Xin-Xin Cui, Ya-Wen Tan, Peng-Xin Dong, Yan-Qiu Ou, Qing-Qing Li, Chu Chu, Lu-Yin Wu, Li-Xia Liang, Shuang-Jian Qin, Mohammed Zeeshan, Yang Zhou, Li-Wen Hu, Ru-Qing Liu, Xiao-Wen Zeng, Guang-Hui Dong, and Xiao-Miao Zhao
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PFOS ,PFOA ,PFAS alternatives ,Mixture ,Liver function ,Environmental sciences ,GE1-350 - Abstract
Experimental evidence has shown that per- and polyfluoroalkyl substances (PFAS) alternatives and mixtures may exert hepatotoxic effects in animals. However, epidemiological evidence is limited. This research aimed to explore associations of PFAS and the alternatives with liver function in a general adult population. The study participants consisted of 1,303 adults from a community-based cross-sectional investigation in Guangzhou, China, from November 2018 to August 2019. We selected 13 PFAS with detection rates > 85% in serum samples and focused on perfluorooctane-sulfonic acid (PFOS), perfluorooctanoic acid (PFOA) and their alternatives [6:2 chlorinated polyfluorinated ether sulfonate (6:2 Cl-PFESA), 8:2 Cl-PFESA, and perfluorohexanoic acid (PFHxA)] as predictors of outcome. Six liver function biomarkers (ALB, ALT, AST, GGT, ALP, and DBIL) were chosen as outcomes. We applied regression models with restricted cubic spline function to explore correlations between single PFAS and liver function and inspected the combined effect of PFAS mixtures on liver by applying Bayesian kernel machine regression (BKMR). We discovered positive associations among PFAS and liver function biomarkers except for ALP. For example, compared with the 25th percentile of PFAS concentration, the level of ALT increased by 12.36% (95% CI: 7.91%, 16.98%) for ln-6:2 Cl-PFESA, 5.59% (95% CI: 2.35%, 8.92%) for ln-8:2 Cl-PFESA, 3.56% (95% CI: −0.39%, 7.68%) for ln-PFHxA, 13.91% (95% CI: 8.93%, 19.13%) for ln-PFOA, and 14.25% (95% CI: 9.91%, 18.77%) for ln-PFOS at their 75th percentile. In addition, higher exposed serum PFAS was found to be correlated with greater odds of abnormal liver function. Analysis from BKMR models also showed an adverse association between PFAS mixtures and liver function. The combined effect of the PFAS mixture appeared to be non-interactive, in which PFOS was the main contributor to the overall effect. Our findings provide evidence of associations between PFAS alternatives, PFAS mixtures, and liver function in the general adult population.
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- 2022
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6. Characteristics of Brain White Matter Microstructure in HIV Male Patients With Primary Syphilis Co-Infection
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Yu Qi, Rui-Li Li, Yuan-Yuan Wang, Wei Wang, Xu-Ze Liu, Jing Liu, Xing Li, Xiao-Dong Zhang, Wen Yu, Jiao-Jiao Liu, Yi-Fan Guo, Bo Rao, and Hong-Jun Li
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HIV ,syphilis ,white matter ,diffusion tensor imaging ,tract-based spatial statistics ,Neurology. Diseases of the nervous system ,RC346-429 - Abstract
Purpose: To investigate the effect of syphilis infection on the microstructure of white matter (WM) in HIV-infected male patients using diffusion tensor imaging (DTI).Methods: Twenty-seven HIV-infected male patients with current syphilis or a history of syphilis (HIV +/syphilis +), twenty-nine HIV-infected male patients without syphilis co-infection (HIV +/syphilis–), and twenty-nine healthy controls (HC) were enrolled. All participants received DTI, and all patients received comprehensive neuropsychological assessment. Tract-based spatial statistics (TBSS) was adopted to analyze the DTI measures: fractional anisotropy (FA), mean diffusivity (MD), axial diffusivity (AD), and radial diffusivity (RD). Correlation analysis was conducted to investigate the relationships between DTI measures and cognitive performance.Results: There were no significant differences in DTI measures between HIV+/syphilis– and HC. Compared with HC, lower FA was found in body of corpus callosum (BCC), splenium of corpus callosum (SCC), genu of corpus callosum (GCC), the bilateral anterior corona radiata (ACR), superior corona radiata (SCR), posterior corona radiata (PCR), and posterior thalamic radiation (PTR) in HIV+/syphilis+ (p < 0.05). Higher RD was found in BCC and SCC (p < 0.05). Compared with HIV+/syphilis–, lower scores were found in complex motor skills (CMS) in HIV+/syphilis+, lower FA was found in BCC, SCC, GCC, the bilateral ACR, SCR, PCR, PTR, cingulate gyrus (CGC), the right inferior fronto-occipital fasciculus (IFO), the retrolenticular part of internal capsule (RLIC), sagittal stratum (SS), external capsule (EC) in HIV+/syphilis+ (p < 0.01). Correlation analysis uncorrected for multiple comparisons showed there was a positive correlation between FA in GCC and CMS, FA in BCC, and CMS in HIV+/syphilis+.Conclusions: Syphilis co-infection can have an additive or synergistic effect on the brain WM in HIV-infected subjects. HIV-infected patients without syphilis should be actively treated to avoid syphilis infection.
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- 2022
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7. The legal class B infectious disease - the 2019 novel coronavirus (2019-nCoV) infected pneumonia in Wuhan, China: a review
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Li LI, Jiao-Jiao LIU, Rong-Hua JIN, and Hong-Jun LI
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coronavirus ,2019-ncov ,covid-19 ,sars ,pneumonia ,respiratory infections ,ct ,Medicine - Abstract
On January 20, 2020, the National Health Commission of the People's Republic of China issued the No. 1 document of 2020, which officially incorporated the 2019 novel coronavirus (2019-nCoV) infected pneumonia into the Class B infectious diseases specified in the Law of the People's Republic of China on the Prevention and Treatment of Infectious Diseases, and adopted the Class A infectious diseases prevention and control measures. The article summarizes the origin of 2019-nCoV infected pneumonia, related concepts, and respiratory coronavirus that often causes unexplained pneumonia. It focuses on the pathology and radiology manifestations of SARS, and the principles of management of 2019-nCoV infected pneumonia.
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- 2020
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8. Fluorogenic Peptide Sensor Array Derived from Angiotensin-Converting Enzyme 2 Classifies Severe Acute Respiratory Syndrome Coronavirus 2 Variants of Concern.
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Wei-Tao Dou, Pei-Hong Tong, Man Xing, Jiao-Jiao Liu, Xi-Le Hu, James, Tony D., Dong-Ming Zhou, and Xiao-Peng He
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- 2024
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9. High-Radiance Shortwave Infrared Light-Emitting Diodes Based on Highly Stable PbS Colloidal Quantum Dots
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Fei Li, Jiao Jiao Liu, Qiulei Xu, Ruiguang Chang, Lei Wang, Zhenghui Wu, Huaibin Shen, and Zuliang Du
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General Materials Science ,Physical and Theoretical Chemistry - Published
- 2023
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10. Elaborating the interplay between the detecting unit and emitting unit in infrared quantum dot up-conversion photodetectors
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Qiulei Xu, Xinxin Yang, Jiao Jiao Liu, Fei Li, Ruiguang Chang, Lei Wang, A Qiang Wang, Zhenghui Wu, Huaibin Shen, and Zuliang Du
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General Materials Science - Abstract
The interplay between PD and QLED units is revealed by regulating the thickness of the PbS layer and illumination intensity.
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- 2023
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11. A homogeneous high-throughput array for the detection and discrimination of influenza A viruses
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Wei-Tao Dou, Xiang Wang, Tingting Liu, Suwen Zhao, Jiao-Jiao Liu, Yao Yan, Jun Li, Chi-Yu Zhang, Adam C. Sedgwick, He Tian, Jonathan L. Sessler, Dong-Ming Zhou, and Xiao-Peng He
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General Chemical Engineering ,Biochemistry (medical) ,Materials Chemistry ,Environmental Chemistry ,General Chemistry ,Biochemistry - Published
- 2022
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12. Chlorinated Polyfluorinated Ether Sulfonates and Thyroid Hormone Levels in Adults: Isomers of C8 Health Project in China
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Qing-Qing Li, Jiao-Jiao Liu, Fan Su, Yun-Ting Zhang, Lu-Yin Wu, Chu Chu, Yuanzhong Zhou, Xubo Shen, Shimin Xiong, Sarah Dee Geiger, Zhengmin Min Qian, Stephen Edward McMillin, Guang-Hui Dong, and Xiao-Wen Zeng
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Alkanesulfonates ,China ,Fluorocarbons ,Thyroid Hormones ,Thyroid Gland ,Thyrotropin ,Bayes Theorem ,General Chemistry ,Ether ,Cross-Sectional Studies ,Alkanesulfonic Acids ,Animals ,Environmental Chemistry ,Ethers - Abstract
Chlorinated polyfluorinated ether sulfonates (Cl-PFESAs) are one kind of replacement chemistry for perfluorooctanesulfonate (PFOS). Recent studies have shown that Cl-PFESAs could interfere with thyroid function in animal models. However, epidemiological evidence on the link between Cl-PFESAs and thyroid function remains scarce. In this study, we focused on two representative legacy perfluoroalkyl substances (PFAS), including PFOS and perfluorooctanoic acid (PFOA), and two PFOS alternatives (6:2 and 8:2 Cl-PFESAs) in the general adult population from a cross-sectional study, the "Isomers of C8 Health Project in China". Three serum thyroid hormones (THs), thyroid stimulating hormone (TSH), free triiodothyronine (FT3), and free thyroxine (FT4), were measured. We fitted generalized linear regression, restricted cubic spline regression, and Bayesian kernel machine regression models to assess associations of individual Cl-PFESAs, legacy PFAS, and PFAS mixtures with THs, respectively. We found individual PFAS and their mixtures were nonlinearly associated with THs. The estimated changes of the TSH level (μIU/mL) at the 95th percentile of 6:2 Cl-PFESA and PFOS against the 5th percentile were -0.74 (95% CI: -0.94, -0.54) and -1.18 (95% CI: -1.37, -0.98), respectively. The present study provided epidemiological evidence for the association of 6:2 Cl-PFESA with thyroid hormone levels in the general adult population.
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- 2022
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13. Volatility of cadmium during pyrolysis of typical low rank coals
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Xiao-bing Wang, Shuang Liu, Mao-lin Ma, Chen Ma, Jiao-jiao Liu, and Ling-mei Zhou
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chemistry.chemical_classification ,Cadmium ,Volatilisation ,Sulfide ,business.industry ,Analytical chemistry ,chemistry.chemical_element ,Sulfur ,chemistry.chemical_compound ,chemistry ,Carbonate ,Organic matter ,Coal ,business ,Pyrolysis - Abstract
The distribution of cadmium (Cd) occurrence modes in a Naomaohu coal (NMH) and an Inner Mongolia high sulfur coal (GL) was investigated using the sequential chemical extraction method. The influence of the occurrence modes, final pyrolysis temperature, heating rate and residence time on the release behavior of Cd during the pyrolysis of two raw coals at 400–800°C in a horizontal/vertical tubular furnace was examined, respectively. The simulation of the migration and transformation of Cd under ideal conditions by FactSage software was carried out. The results show that Cd in NMH and GL is present in an organic matter state by 46% and 37%, a carbonate state by 32% and 24%, a disulfide state by 12% and 1%, and an aluminosilicate state by 10% and 38%, respectively. The distribution of occurrence modes seriously affects the volatilization behavior of Cd, in which the Cd in the organic matter state is easy to volatilize at low temperature, while those in the carbonate, aluminosilicate and sulfide state can volatilize at medium and high temperature; and reducing pyrolysis rate and extending residence time are conducive to the release of Cd. The FactSage simulation shows that Cd, CdO, Cd(OH)x and CdS are the major gaseous products of Cd during the pyrolysis of NMH and GL coal, and the difference of volatilization behavior of Cd in two kinds of coal is mainly determined by pyrolysis temperature, distribution of occurrence modes and coal rank, which are in good agreement with the experimental results.
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- 2021
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14. Therapeutic experience of an 89-year-old high-risk patient with incarcerated cholecystolithiasis: A case report and literature review
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Xiao-Ting Ma, Jiao-Jiao Liu, Bai-Jiang Wan, Li-Li Liu, Feng-Yuan Li, Jia-Hong Liao, Pei-Ying Yuan, Ming-Wen Zhu, Rui-Jiao Yuan, Man Wang, Xi-Ai Guo, Limin Liu, Hai Deng, Fang Wu, Niu-Niu Huang, Tian-Tian Liu, Chong Zhang, Xue Wen, Zhuo Liu, Yu-Jiao Gao, Xue-Ting Wang, Hai-Yan Yang, Jing Zhao, Yue Zhao, Miao-Miao Zhang, Zong-Ming Zhang, Fang Liao, and Hong-Yan Zhu
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2019-20 coronavirus outbreak ,medicine.medical_specialty ,High risk patients ,Coronavirus disease 2019 (COVID-19) ,business.industry ,General surgery ,Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) ,Acute gangrenous cholecystitis ,COVID-19 ,General Medicine ,Acute abdominal diseases ,Cholecystolithiasis incarceration ,03 medical and health sciences ,0302 clinical medicine ,Extremely elderly patient ,030220 oncology & carcinogenesis ,Case report ,medicine ,030211 gastroenterology & hepatology ,business - Abstract
BACKGROUND The global pandemic of coronavirus disease 2019 pneumonia poses a particular challenge to the emergency surgical treatment of elderly patients with high-risk acute abdominal diseases. Elderly patients are a high-risk group for surgical treatment. If the incarceration of gallstones cannot be relieved, emergency surgery is unavoidable. CASE SUMMARY We report an 89-year-old male patient with acute gangrenous cholecystitis and septic shock induced by incarcerated cholecystolithiasis. He had several coexisting, high-risk underlying diseases, had a history of radical gastrectomy for gastric cancer, and was taking aspirin before the operation. Nevertheless, he underwent emergency laparoscopic cholecystectomy, with maintenance of postoperative heart and lung function, successfully recovered, and was discharged on day 8 after the operation. CONCLUSION Emergency surgery for elderly patients with acute abdominal disease is safe and feasible during the coronavirus disease 2019 pandemic, the key is to abide strictly by the hospital’s epidemic prevention regulations, fully implement the epidemic prevention procedure for emergency surgery, fully prepare before the operation, accurately perform the operation, and carefully manage the patient postoperatively.
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- 2020
15. Preparation of a novel hydrophobic interaction chromatography with higher selectivity by introducing spatial recognition
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Deman Han, Kai-Bin Li, Yi‐Ting Lu, Ye‐Jing Deng, Chen‐Yi Wang, Siqi Zhang, Wei Shi, and Jiao‐Jiao Liu
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General Chemical Engineering ,Salt (chemistry) ,02 engineering and technology ,010501 environmental sciences ,01 natural sciences ,Inorganic Chemistry ,Adsorption ,Protein purification ,Bovine serum albumin ,Waste Management and Disposal ,0105 earth and related environmental sciences ,chemistry.chemical_classification ,Chromatography ,biology ,Renewable Energy, Sustainability and the Environment ,Chemistry ,Hydrophilic interaction chromatography ,Organic Chemistry ,021001 nanoscience & nanotechnology ,Pollution ,Fuel Technology ,Adsorption kinetics ,biology.protein ,0210 nano-technology ,Selectivity ,Biotechnology ,Protein adsorption - Abstract
BACKGROUND: Hydrophobic interaction chromatography (HIC), as a typical separation technology, often suffers from low selectivity because it has a single interaction mode. Herein, a novel HIC resin (Octyl@BSA) with imprinted layer was synthesized and used for protein adsorption. Bovine serum albumin (BSA) and bovine serum γ‐globulin (bIgG) were used as model competitive proteins in this study. The effects of pH, salt type, concentration, and mass ratio were then investigated. RESULTS: The data from the static and dynamic adsorption experiments indicated that the introduction of spatial recognition effectively reduced the adsorption of competitive proteins, leading to significant improvements in selectivity. In comparison with raw HIC resin, Octyl@BSA retained a high binding capacity for BSA but rejected other proteins through spatial recognition. The maximum selectivity factors (α) of this resin may be close to 5. The adsorption kinetics and frontal adsorption experiments further confirmed the improvement in selectivity in batch and column mode. In addition, the recyclability of Octyl@BSA was tested using ten continuous BSA adsorption–desorption cycles. CONCLUSION: This study demonstrated that the introduction of spatial recognition was an effective strategy for enhancing the advantage of target proteins during competitive adsorption, leading to an improvement in selectivity for HIC. © 2020 Society of Chemical Industry
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- 2020
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16. Study on Reasonable Production in X Gas Field
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Lei-lei Wang, Hong-fei Chen, Jiao-jiao Liu, and Wei-wei Hu
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- 2022
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17. The application of digital technology in Dali 'Fengtu Yicang' scenic spot
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Jiao Jiao Liu, Yun Ma, and Yuan Zhi
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General Medicine - Abstract
With the continuous development of the digital era, it is not only a technical means of processing information, but also a demonstration of scientific and technological progress. The advent of the digital era provides a new creative idea for us to reproduce the irreparable buildings. However, as a national granary, Fengtu Charity Warehouse is mainly displayed in a single scenic spot, lacking diversified display forms, which reduces the popularity of Fengtu Charity Warehouse.
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- 2023
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18. Sarcodon aspratus polysaccharides ameliorated obesity-induced metabolic disorders and modulated gut microbiota dysbiosis in mice fed a high-fat diet
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Yong-Ming Lu, Yan Chen, Jiao-Jiao Liu, Chan Zhang, Lei Chen, Wen-Juan Pan, Wen-Na Zhang, Chenchen Yan, and Juan Chen
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0301 basic medicine ,Simvastatin ,medicine.medical_specialty ,Adipose tissue ,030209 endocrinology & metabolism ,Gut flora ,Diet, High-Fat ,Weight Gain ,Mice ,03 medical and health sciences ,chemistry.chemical_compound ,0302 clinical medicine ,Metabolic Diseases ,Polysaccharides ,Internal medicine ,Adipocyte ,Glucose Intolerance ,medicine ,Animals ,Obesity ,Hypolipidemic Agents ,Inflammation ,biology ,Basidiomycota ,Akkermansia ,General Medicine ,Lipid Metabolism ,biology.organism_classification ,medicine.disease ,Gastrointestinal Microbiome ,Metabolism disorder ,Oxidative Stress ,030104 developmental biology ,Endocrinology ,Adipose Tissue ,Liver ,chemistry ,Dietary Supplements ,Lipogenesis ,Steatosis ,Dysbiosis ,Food Science - Abstract
Sarcodon aspratus is a popular edible fungus that has commonly been used as a functional food in China and other Asian countries. This study is conducted to examine the potential health benefits of Sarcodon aspratus polysaccharides (SATPs), on obesity and related metabolism disorders. C57BL/6J mice were fed with a high-fat diet (HFD) and supplemented with SATPs (100-400 mg kg-1) for 14 weeks. The results indicated that SATP treatment markedly reduced HFD-induced body weight gain and fat accumulation in a dose-dependent manner. SATPs could improve lipid homeostasis and glucose tolerance in HFD-fed mice. Furthermore, SATP intervention significantly attenuated hepatic steatosis, liver oxidative stress and inflammation. Additionally, we detected the macrophage and mRNA levels of lipogenesis markers in epididymal adipose tissues, and the results revealed that SATPs exerted inhibitory effects on the activation of immune cells and adipocyte differentiation in adipose tissues. High-throughput pyrosequencing of 16S rRNA suggested that SATP intervention was able to down-regulate the Firmicutes-to-Bacteroidetes ratio, and also increase the relative abundance of Lactobacillus, Bacteroides and Akkermansia in mice with HFD challenge. Taken together, SATPs showed ameliorative effects on hepatic steatosis, inflammation and adipocyte differentiation in HFD-fed mice. Notably, SATPs could modulate HFD-induced dysbiosis of gut microbiota. Thus, they might be a potential health supplement or prebiotic in the prevention of obesity and related metabolic disorders.
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- 2020
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19. Corrosion characteristics of Fe3Si intermetallic coatings prepared by molten salt infiltration in sulfuric acid solution
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Fu-rong Wen, Chen Hongxia, Nijun Xu, Juanqin Xue, Tao Guanyu, Jiao-jiao Liu, and Tang Changbin
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Materials science ,Passivation ,Carbon steel ,Mechanical Engineering ,Metallurgy ,Alloy steel ,technology, industry, and agriculture ,Metals and Alloys ,02 engineering and technology ,engineering.material ,010402 general chemistry ,021001 nanoscience & nanotechnology ,Microstructure ,01 natural sciences ,0104 chemical sciences ,Corrosion ,Diffusion layer ,Coating ,Mechanics of Materials ,Materials Chemistry ,engineering ,Molten salt ,0210 nano-technology - Abstract
Alloyed Fe3Si intermetallic compound coatings were prepared through non-electrolysis high-temperature infiltration in molten salt on the surface of AISI420 and AISI304 stainless steel containing Cr and Cr, Ni elements, compared with Fe3Si coating on A3 carbon steel surface. The microstructure of infiltration coatings was examined by means of X-ray diffraction (XRD), scanning electron microscopy (SEM), and glow discharge optical emission spectroscopy. The electrochemical corrosion properties and behavior of Fe3Si coatings in H2SO4 solution were evaluated via electrochemical techniques and static immersion tests. The results revealed that the permeation coatings prepared on the stainless steel surface are composed of a Cr- and Cr-, Ni-alloyed Fe3Si intermetallic-compound layer and a diffusion layer. Owing to the presence of alloying elements Cr and Ni from the substrate, the permeation coatings were relatively thick, dense, and contained only a few defects. The Cr-, Ni-alloyed Fe3Si coating prepared on AISI304 surface was the most compact, contained fewer defects, and was thicker than the coating prepared on AISI420. The Fe3Si infiltration coatings exhibited significant passivation characteristics in 10 vol% H2SO4 aqueous solution. Alloyed Fe3Si coatings of AISI420 and AISI304 exhibit better corrosion resistance in 10 vol% and 20 vol% H2SO4 than the Fe3Si coating of carbon steel. Therefore, these coatings can protect both types of stainless steel from surface corrosion. The best corrosion resistance was realized for the alloyed Fe3Si coating on AISI304 surface. The corrosion resistance and protection performance of Fe3Si intermetallic-compound coatings in H2SO4 solution are directly correlated with the thickness, compactness, defect characteristics, and passivation properties of the infiltration coatings. However, alloying elements from the alloy steel substrates had a significant effect on these four factors, during the infiltration process in the molten salt.
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- 2019
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20. The effects of Cl-PFESAs exposure on blood lipids - A community-based large population study in Guangzhou
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Pengxin Dong, Yun-Ting Zhang, Lu-Yin Wu, Shimin Xiong, Xin Mi, Yanqiu Ou, Jiao-Jiao Liu, Wenru Feng, Chu Chu, Qing-Qing Li, Guang-Hui Dong, Hong-Yao Yu, Yang Zhou, Xiao-Wen Zeng, Yuanzhong Zhou, Peien Zhou, Qiu-Ling Fang, Fan Su, Zhengmin Min Qian, and Xubo Shen
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Community based ,medicine.medical_specialty ,China ,Fluorocarbons ,Environmental Engineering ,business.industry ,Large population ,Community resident ,Blood lipids ,Physiology ,medicine.disease ,Pollution ,Lipids ,Alkanesulfonic Acids ,Unit increase ,Research Design ,Epidemiology ,Environmental Chemistry ,Medicine ,business ,Waste Management and Disposal ,Dyslipidemia - Abstract
Numerous epidemiological studies have investigated the lipid interference effects of legacy PFASs, however, no studies on PFAS alternatives and blood lipids have been published. In this study, we explored the association between Cl-PFESAs, a typical PFASs alternative in China, and blood lipid profiles in 1336 Guangzhou community residents using linear and non-linear regression models. The results showed a deleterious effect of Cl-PFESAs and blood lipids: adjusted estimates (β) for TC, TG, LDL-C and HDL-C per natural log unit increase of 6:2 Cl-PFESA were 0.029 (95% CI: 0.020, 0.038), 0.075 (95% CI: 0.049, 0.101), 0.035 (95% CI: 0.021, 0.049) and -0.071 (95% CI: -0.084, -0.058), respectively. The association between Cl-PFESAs and dyslipidemia was also positively significant (P 0.05). Furthermore, a non-linear relationship was observed in Cl-PFESAs and serum lipid levels using a restricted cubic splines (RCS) model. In summary, our research suggested a negative impact of Cl-PFESAs on blood lipid patterns and a possible non-linear association.
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- 2021
21. Efficacy of tamoxifen in combination with low dose testosterone undecanoate in the treatment of idiopathic male infertility: a meta-analysis
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Jian-guo Liu, Bin Guo, and Jiao-jiao Liu
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medicine.medical_specialty ,business.industry ,Meta-analysis ,Low dose ,Urology ,medicine ,business ,medicine.disease ,Tamoxifen ,medicine.drug ,Male infertility - Published
- 2021
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22. Characteristics of Brain Structure in HIV Male Patients with Syphilis Co-Infection: A Cross-Sectional Study
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Wen Yu, Qi Y, Xu-Ze Liu, Ming-Ming Liu, Rui-Li Li, Xiao-Dong Zhang, Pei-Hong Ma, Jiao-Jiao Liu, Jing Liu, Yuanyuan Wang, Hongjun Li, Wei Wang, Li Xing, and Yi-Fan Guo
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medicine.medical_specialty ,Cross-sectional study ,business.industry ,Human immunodeficiency virus (HIV) ,medicine.disease ,medicine.disease_cause ,behavioral disciplines and activities ,nervous system ,Male patient ,Internal medicine ,medicine ,Syphilis ,business ,psychological phenomena and processes ,Co infection - Abstract
Background To investigate the effect of syphilis infection on the microstructure of white matter (WM) in HIV-infected male patients through comparing the differences of WM between HIV-infected male patients with and without syphilitic infection using diffusion tensor imaging (DTI).Methods 27 HIV-infected male patients with current syphilis or a history of syphilis (HIV+/syphilis+) and 29 HIV-infected male patients without syphilis co-infection history (HIV+/syphilis-) were enrolled. All patients received DTI and comprehensive neuropsychological assessment. Clinical data were compared between the two groups with T-test, Mann-Whitney U Test and Chi-square Test. Tract-based spatial statistics (TBSS) was adopted to analyze the DTI metrics. Multiple linear regression analysis was conducted to investigate the relationships between DTI metrics and clinical variables and cognitive performance. Results In the HIV+/syphilis+ group, decreased AD was found in the right superior corona radiata (SCR-R) and body of corpus callosum (BCC); increased RD was found in the bilateral posterior corona radiata (PCR), the right posterior thalamic radiation (PTR-R), the left SCR (SCR-L), splenium of corpus callosum (SCC) and BCC; decreased FA was found in multiple regions. AD in BCC was negatively correlated with CD4/CD8 ratios. AD in SCR-R was positively correlated with CD4/CD8 ratios. Patients in HIV+/syphilis+ group had a lower score in complex motor skills (CMS). RD in SCC and SCR-L was negatively correlated with CMS; RD in PTR-R was positively correlated with CMS. AD in SCR-R was positively correlated with CMS. Conclusions Compared with patients simply infected with HIV, the integrity of WM is more seriously impaired in HIV-infected patients with syphilis co-infection, and it may accelerate the impairment of cognitive function.
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- 2021
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23. Production Allocation Analysis of Commingle Production Wells in Multi-layer Tight Gas Reservoirs
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Chao Jia, Qian Liu, Jiao-jiao Liu, Zhi-jun Liu, and Hai-bo Zhang
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Computer program ,Petroleum engineering ,Natural gas ,business.industry ,Perforation (oil well) ,Production (economics) ,Environmental science ,Linear interpolation ,Layer (object-oriented design) ,business ,Tight gas ,Test data - Abstract
The efficient and rational development of tight gas reservoirs, most of which are deposit of multiple layers, is becoming a new global focus. The major tight gas reservoirs in China have multiple production layers. Gas wells are completed with multiple fracture treatments, and are commingled production. It is very difficult to effectively evaluate the single-layer production contribution and the use of each layer’s reserves. This paper presents an approach to solve the problem, which is basically based on the application of Pearson correlation analysis, catastrophe theory, and linear interpolation to calculate the single-layer production allocation rates. The method can quickly evaluate the stratified production of a large number of gas wells at different times through a computer program. The error of method validation, comparing the method prediction value with the production test data, is less than 10%. In field application, after the gas flows the discharge boundary, the production of the main layer will decrease due to the decrease in gas production of the multi-layer gas well, and other non-main layers may rise or have little change. In another case, the non-main layer can produce more natural gas for the gas well increases production. The method will also provide guidance for optimizing the perforation section of a gas well. Additionally, based on the production of a single gas well, the cumulative gas production of each layer can be calculated to evaluate the dynamic reserves of each layer and analyze the reserves utilization of each single layer. This work will finally provide guidance for gas well encryption to improve the multi-layer tight gas reservoir recovery.
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- 2021
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24. Adaptability Evaluation of Horizontal Well Development in Shenmu Multi-layer Tight Gas Reservoir
- Author
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Ye Wang, De-long Wang, Jiao-jiao Liu, and Hai-bo Zhang
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Natural gas field ,Permeability (earth sciences) ,Petroleum engineering ,Computer simulation ,media_common.quotation_subject ,Mode (statistics) ,Development (differential geometry) ,Tight gas ,Adaptability ,Geology ,media_common ,Physical property - Abstract
Shenmu Gas Field is a multilayer tight sandstone gas reservoir with low vertical well production. The task of gas field productivity construction is heavy. It is an effective way to increase the production of a single well by excavating local superior areas and implementing horizontal well development. Therefore, it is necessary to evaluate the adaptability and establish the reservoir limits of horizontal well in Shenmu Gas Field. Systematically study the superposition mode and development scale of reservoir sand bodies, and use the reserve concentration to divide the multi-layer gas reservoirs into three types, and they are single-layer, double-layer and multi-layer, respectively. The numerical simulation method is used to compare the development effects of horizontal wells and vertical wells, to determine the reserves concentration limits and reserves physical property limits of horizontal well development. The selection criteria for geological targets suitable for horizontal well is established. The research shows that ① A large-scale composite effective reservoir is formed in the local area of the Taiyuan Formation and Shan2 Formation in Shenmu Gas Field, with a length of 1600–3200 m and a width of 800–2000 m, and it has the geological conditions for horizontal well development; ② the reserve concentration in the main development zone of the horizontal well should be over 75%, and it should have a continuous effective thickness of 5.0 m, The permeability ratio between the primary and the secondary layer should be between 0.8 and 3.9; ③ the Shenmu Gas Field is generally not suitable for large-scale horizontal well overall development, but is suitable for centralized development in local single-layer advantageous areas. The research result can provide technical support for the horizontal wells of similar gas reservoirs at home and abroad, and are of great significance for the efficient development of gas fields.
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- 2021
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25. Orthogonal construction of dual dynamic covalent linkages toward an 'AND' logic-gate acid-/salt-responsive block copolymer
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Wu-Cheng Nie, Si-Chong Chen, Qian Xiao, Jiang-Ling Zhou, Yu-Zhong Wang, Fei Song, Xiao-Hui Wang, Xiu-Li Wang, and Jiao-Jiao Liu
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chemistry.chemical_classification ,Aqueous solution ,Polymers and Plastics ,Organic Chemistry ,technology, industry, and agriculture ,Salt (chemistry) ,02 engineering and technology ,Polymer ,010402 general chemistry ,021001 nanoscience & nanotechnology ,01 natural sciences ,Micelle ,0104 chemical sciences ,chemistry.chemical_compound ,chemistry ,Covalent bond ,Polymer chemistry ,Materials Chemistry ,Copolymer ,Acid salt ,0210 nano-technology ,Ethylene glycol - Abstract
A novel block copolymer is fabricated by orthogonally coupling two end-functionalized polymers, glucose-capped methoxypoly(ethylene glycol) (mPEG2k-diol) and phenylboronic acid-capped poly(e-caprolactone) (PBA-PCL), with dual boronate ester and B N/B O dynamic covalent interactions. Due to their synergetic effect, this block copolymer can self-assemble into micelles in aqueous solution with high stability. More importantly, micellar disassembly can be only triggered in the presence of both signal inputs, acid and salt, displaying an “AND” logic-gate responsive behavior.
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- 2018
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26. [Untitled]Safety, compatibility and function of metallic dental materials
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Hua, Yu, Xiao-dong, Zhang, Yi-jing, Wang, Jing, Wei, and Jiao-jiao, Liu
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- 2012
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27. [Untitled]Safety, compatibility and function of metallic dental materials
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Hua, Yu, Xiao-dong, Zhang, Yi-jing, Wang, Jing, Wei, and Jiao-jiao, Liu
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- 2012
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28. Sexual Steroids and their Receptors Affect Microglia-Mediated Neuroinflammation in Neurodegenerative Diseases
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Xi He, Jing Shan Shi, Jie Liu, and Jiao Jiao Liu
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0301 basic medicine ,Microglia ,business.industry ,General Medicine ,Disease ,Affect (psychology) ,03 medical and health sciences ,030104 developmental biology ,0302 clinical medicine ,medicine.anatomical_structure ,medicine ,business ,Receptor ,Neuroscience ,030217 neurology & neurosurgery ,Neuroinflammation ,Biomedical sciences - Abstract
Neurodegenerative diseases, including Alzheimer’s disease (AD) and Parkinson’s disease (PD), are generally featured by neuroinflammation and procedural loss of selectively vulnerable...
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- 2020
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29. Research on the Technology of Supercharging in Low Permeability Gas Field
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Qian Liu, Jiao-jiao Liu, Hai-bo Zhang, Hai-long Zuo, and Hong-fei Chen
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Natural gas field ,Cabin pressurization ,Petroleum engineering ,Wellhead ,Low permeability ,Environmental science ,Parameter design - Abstract
Pressurized exploitation is one of the important measures to ensure the continuous and efficient exploitation of gas field by reducing wellhead pressure and increasing external transportation pressure in the later period of gas field exploitation. As a typical low permeability gas field, the south area of yulin gas field has entered a decline period. The surface gathering and transportation system has been unable to adapt to the development of middle and low pressure gas reservoirs. How to carry out pressurized mining economically and effectively has become an urgent problem to be solved. In view of difficulties in gas field development, key parameters such as the timing, mode, scale and minimum wellhead pressure of pressurized gas field exploitation were studied by taking production, gathering and transportation system and economic factors into consideration. The key technology of the pressurization of low permeability gas reservoir in southern yulin gas field is formed.
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- 2020
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30. Reduction of 5-fluorouracil-induced toxicity by Sarcodon aspratus polysaccharides in Lewis tumor-bearing mice
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Chan Zhang, Juan Chen, Lei Chen, Yan Chen, Shomaila Mehmood, Yong-Ming Lu, Chenchen Yan, Ya Wang, Qing-Xi Wu, Wen-Juan Pan, Jiao-Jiao Liu, and Wen-Na Zhang
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MAPK/ERK pathway ,Male ,Combination therapy ,medicine.medical_treatment ,p38 mitogen-activated protein kinases ,Interleukin-1beta ,02 engineering and technology ,Pharmacology ,Biochemistry ,03 medical and health sciences ,Carcinoma, Lewis Lung ,Mice ,Immune system ,Structural Biology ,Cell Line, Tumor ,medicine ,Animals ,Molecular Biology ,030304 developmental biology ,0303 health sciences ,Kidney ,Chemistry ,Basidiomycota ,Fungal Polysaccharides ,General Medicine ,021001 nanoscience & nanotechnology ,Immunohistochemistry ,Xenograft Model Antitumor Assays ,Small intestine ,Tumor Burden ,Disease Models, Animal ,medicine.anatomical_structure ,Toxicity ,Fluorouracil ,0210 nano-technology ,Adjuvant ,Drug Antagonism - Abstract
5-Fluorouracil (5-Fu) is an effective anticarcinogenic agent, however, continuous use of 5-Fu may cause severe side effects. The goal of this study was to investigate the effectiveness of Sarcodon aspratus polysaccharides (SATP) in alleviating 5-Fu-induced toxicity in Lewis tumor-bearing mice. Lewis tumor-bearing mice were treated with saline, SATP, 5-Fu or 5-Fu + SATP. The results indicated that compared to the 5-Fu group, the 5-Fu + SATP group showed effective amelioration of the liver, kidney and small intestine injury caused by 5-Fu and decreases in the levels of related biochemical indicators, such as aspartate aminotransferase (AST), alanine aminotransferase (ALT) and urea nitrogen (BUN). Additionally, the combination therapy enhanced the quality of life and immune organ indexes of mice. Further mechanistic studies indicated that the 5-Fu + SATP group showed a decrease in hepatotoxicity caused by 5-Fu via a reduction in the levels of interleukin-1β (IL-1β), an increase in the expression of Bcl-2 and decreases in the expression of p-p38, p-JNK and Bax. Collectively, the results indicated that SATP could significantly alleviate the toxicity of 5-Fu in Lewis tumor-bearing mice and showed the hepatoprotective capability of SATP via its effect on the expression levels of inflammatory factors and components of the MAPK/P38/JNK pathway, which shows that it may be a potential adjuvant for the chemotherapeutic drug 5-Fu in cancer treatment.
- Published
- 2019
31. Effect of carbon addition on the microstructure and mechanical properties of Nb-30Ti-18Al alloy
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Lin Guo, Jiao-Jiao Liu, L.R. Xiao, C.X. Yu, X.J. Zhao, and Z.Y. Cai
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010302 applied physics ,Materials science ,Annealing (metallurgy) ,Mechanical Engineering ,Alloy ,Metallurgy ,02 engineering and technology ,engineering.material ,021001 nanoscience & nanotechnology ,Condensed Matter Physics ,Microstructure ,01 natural sciences ,Carbide ,Fracture toughness ,Mechanics of Materials ,0103 physical sciences ,Volume fraction ,engineering ,General Materials Science ,Composite material ,0210 nano-technology ,Strengthening mechanisms of materials ,Solid solution - Abstract
The Nb-30Ti-18Al alloys doped with the amounts of 0 at%, 1 at% and 5 at% carbon were prepared by arc melting and annealing. The effects of carbon addition on the microstructure and mechanical properties of Nb ss /Nb 3 Al in situ composites as well as the strengthening mechanisms were investigated. The results showed that during annealing at 1200 °C, supersaturated Nb ss decomposed and Nb 3 Al phase precipitated in C-free alloy, while carbide decomposed with the precipitation of Nb 3 Al in C-doped alloys. Furthermore, the orientation relationship of Nb 3 Al phase and the surrounding (Nb, Ti)C was observed in Nb-30Ti-18Al-5C (NA5) alloy. Additionally, with increasing the carbon content, the compressive strength of alloys at high temperature were improved significantly ascribed to the occurrence of solid solution and volume fraction increase of strengthen phase, while the fracture toughness decreased due to the volume fraction decrease of Nb ss .
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- 2016
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32. Microstructure evolution of Al–Zn–Mg–Cu alloy during non-linear cooling process
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Hui Zhao, Wei-chen Yu, Hong-ying Li, De-wang Li, and Jiao-jiao Liu
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010302 applied physics ,Materials science ,Precipitation (chemistry) ,Alloy ,Metallurgy ,Metals and Alloys ,02 engineering and technology ,engineering.material ,Atmospheric temperature range ,021001 nanoscience & nanotechnology ,Geotechnical Engineering and Engineering Geology ,Condensed Matter Physics ,Microstructure ,01 natural sciences ,Electrical resistivity and conductivity ,Phase (matter) ,0103 physical sciences ,Materials Chemistry ,engineering ,Grain boundary ,Composite material ,0210 nano-technology ,Ductility - Abstract
The microstructure evolution and properties of an Al–Zn–Mg–Cu alloy were investigated under different non-linear cooling processes from the solution temperature, combined with in-situ electrical resistivity measurements, selected area diffraction patterns (SADPs), transmission electron microscopy (TEM), and tensile tests. The relative resistivity was calculated to characterize the phase transformation of the experimental alloy during different cooling processes. The results show that at high temperatures, the microstructure evolutions change from the directional diffusion of Zn and Mg atoms to the precipitation of S phase, depending on the cooling rate. At medium temperatures, η phase nucleates on Al 3 Zr dispersoids and grain boundaries under fast cooling conditions, while S phase precipitates under the slow cooling conditions. The strength and ductility of the aged alloy suffer a significant deterioration due to the heterogeneous precipitation in medium temperature range. At low temperatures, homogeneously nucleated GP zone, η ' and η phases precipitate.
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- 2016
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33. [The Effect in Extraction of Different Ratio of Dahuang-Taoren for Ten Kinds of Chemical Constituents from Rhizoma Rhei]
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Yong-gang, Yan, Li-min, Yin, Hong-yan, Wang, Jie, Wang, Jiao-jiao, Liu, and Chong, Deng
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Sennosides ,Emodin ,Senna Extract ,Anthraquinones ,Rheum ,Chromatography, High Pressure Liquid ,Rhizome ,Drugs, Chinese Herbal - Abstract
To investigate the effect of Dahuang-Taoren with different proportion of extraction amount changes of ten kinds of chemical constituents in Rhizoma Rhei.Uniform method to set different ratio( 1∶ 5,2∶ 5,2∶ 3,1∶ 1,3∶ 2,5∶ 2,5∶ 1),and set the control group ( Dahuang-Taoren( 1 ∶ 0). HPLC was used to determine the content of ten constituents as gallic acid,( +)-catechin,sennoside B,anthraquinones( aloe-emodin,rhein,emodin,chrysophanol,physcion,chrysophanol-1-O-glucoside,emodin major grape glycoside) in different ratio of drug. Different proportions of Dahuang-Taoren on the extraction amount of ten chemical components in Rhizoma Rhei changes were analyzed. .Compared to the control group, Dahuang-Taoren with different ratio( 5∶ 1,5∶ 2,3∶ 2) in a sample with increasing proportion of Taoren,the extraction amount of ten kinds of constituents of Rhizoma Rhei gradually decreased;Dahuang-Taoren with ratio of 1∶ 1,ten kinds of constituents in extraction of total amount arrived minimum value. Dahuang-Taoren with different ratio( 2∶ 3,2∶ 5,1∶ 5) in a sample with increasing proportion of Taoren,the extraction amount of gallic acid,( +) catechin,chrysophanol of Rhizoma Rhei increased significantly.There is obvious change in chemical constituents of the extraction amount of Rhizoma Rhei with the change of the ratio in Dahuang-Taoren, and Dahuang-Taoren with the ratio( 2∶ 3,2∶ 5,1∶ 5),the extraction amount of gallic acid,( +)-catechin,sennoside B,aloe-emodin,emodin,chrysophanol,physcion,chrysophanol-1-O-glucoside are significantly higher than control group.
- Published
- 2018
34. Application of novel physical picture based on artificial neural networks to predict microstructure evolution of Al–Zn–Mg–Cu alloy during solid solution process
- Author
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De-wang Li, Yue Wu, Jiao-jiao Liu, and Hong-ying Li
- Subjects
Materials science ,Scanning electron microscope ,Alloy ,Metallurgy ,Metals and Alloys ,Recrystallization (metallurgy) ,engineering.material ,Geotechnical Engineering and Engineering Geology ,Condensed Matter Physics ,Microstructure ,law.invention ,Optical microscope ,law ,Electrical resistivity and conductivity ,Materials Chemistry ,engineering ,Composite material ,Tensile testing ,Solid solution - Abstract
The effects of the solid solution conditions on the microstructure and tensile properties of Al–Zn–Mg–Cu aluminum alloy were investigated by in-situ resistivity measurement, optical microscopy (OM), scanning electron microscopy (SEM), transmission electron microscopy (TEM) and tensile test. A radial basis function artificial neural network (RBF-ANN) model was developed for the analysis and prediction of the electrical resistivity of the tested alloy during the solid solution process. The results show that the model is capable of predicting the electrical resistivity with remarkable success. The correlation coefficient between the predicted results and experimental data is 0.9958 and the relative error is 0.33%. The predicted data were adopted to construct a novel physical picture which was defined as “solution resistivity map”. As revealed by the map, the optimum domain for the solid solution of the tested alloy is in the temperature range of 465–475 °C and solution time range of 50–60 min. In this domain, the solution of second particles and the recrystallization phenomenon will reach equilibrium.
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- 2015
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35. Electrochemical Performance of Pure Sn and Sn/Ti Composite Thin Film Cathodes for Lithium Ion Battery
- Author
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Liang Xiong, Jiao-jiao Liu, Yi Xie, and Ke-yang Wan
- Subjects
Materials science ,Scanning electron microscope ,chemistry.chemical_element ,02 engineering and technology ,Sputter deposition ,010402 general chemistry ,021001 nanoscience & nanotechnology ,Electrochemistry ,01 natural sciences ,Lithium-ion battery ,0104 chemical sciences ,chemistry ,Chemical engineering ,Lithium ,Thin film ,Cyclic voltammetry ,0210 nano-technology ,Tin - Abstract
Pure thin film, Sn/Ti, Sn/C composite thin film cathodes were prepared by magnetron sputtering technology. Electrochemical performance of these thin film cathodes for lithium ion battery has been investigated by scanning electron microscope (SEM), X-ray diffraction (XRD), galvanostatic charge and discharge, and cyclic voltammetry. For the pure tin thin film, the relationship between the 1st cycle capacity lost and SEI capacity was studied. And the reason of SEI capacity evolution versus deposition time was explained, where the 1st cycle capacity lost and cycle performance both decrease as the deposition time grown. For the composite thin film, the addition of Ti made the flat potential plateaus of lithium ion battery into a slop curve, but effectively improves the cycle performance. Although it caused some tin inactive to lithium ion.
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- 2018
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36. Fracture Analysis on Reinforced Concrete Poles
- Author
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Ke-yang Wan, Jiao-jiao Liu, Zhi Cao, and Liang Xiong
- Subjects
business.industry ,Ultimate tensile strength ,Structural engineering ,Dimension measurement ,business ,Reinforced concrete ,Analysis method ,Geology - Abstract
Two reinforced concrete poles in one substation fractured suddenly, damaging a transformer and related equipment. So the causes of the fracture of the reinforced concrete poles are analyzed with macroscopic inspection, dimension measurement of inner wires, and other analysis methods of chemical composition and mechanical properties. The analysis results show that serious quality problems, including substandard tensile strength, substandard yield strength, unacceptable weight and unacceptable composition, as well as inadequate burial depth of the two poles during construction are the main causes of fracture.
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- 2018
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37. The Influence of NaCl Concentration on Salt Spray Corrosion Behavior of P92 Steel
- Author
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Chao Feng, Bi-Cao Peng, Jiao-Jiao Liu, Yi Long, and Tangqing Wu
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chemistry.chemical_classification ,Materials science ,Scanning electron microscope ,020209 energy ,Diffusion ,Oxide ,Salt (chemistry) ,02 engineering and technology ,Chloride ,Corrosion ,Ion ,chemistry.chemical_compound ,chemistry ,0202 electrical engineering, electronic engineering, information engineering ,medicine ,Ferric ,Nuclear chemistry ,medicine.drug - Abstract
In the paper, the neutral salt spray with various NaCl concentration was carried out, and effect of NaCl concentration on P92 steel corrosion behaviour was studied by weight loss, macro-appearances and scanning electron microscope/energy dispersive spectrometer (SEM/EDS). The results showed the formation rate and amount of corrosion product would rise according with elevated chloride ion concentration which were composed of ferric oxide and chromic oxide.The corrosion process of P92 steel during neutral salt spray was mainly non-uniform corrosion, the compact corrosion product formed in early stage could hinder the diffusion of corrosive ion.
- Published
- 2018
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38. [Effect of polysaccharides from Polygonatum sibiricum on lipid-metabolism related mRNA and protein expression in hyperlipidemic mice]
- Author
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Xia, Kong, Jiao-Jiao, Liu, Hui, Li, and Zhang-Bao, Chen
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Mice ,Random Allocation ,Polysaccharides ,Phytochemicals ,Polygonatum ,Animals ,Hyperlipidemias ,RNA, Messenger ,Lipid Metabolism - Abstract
To study the effect of polysaccharides from Polygonatum sibiricum on mRNA and protein expressions of blood lipid metabolism in hyperlipidemic mice. The mice were randomly divided into 6 groups, namely the blank control group, the hyperlipidemia model group, the simvastatin group, and low, middle and high-dose PSP groups (200, 400, 800 mg·kg⁻¹·d⁻¹). Each group of the mice was administrated intragastrically for 14 days, respectively. Subsequently, every group of mice, except for the blank control group, was intraperitoneally injected with 75% fresh egg yolk emulsion for establishing the hyperlipidemic mice model. Upon completion of the administration, the contents of TC, TG, LDL-C and HDL-C in serum of each group were investigated in details. In particular, the mRNA expression levels of PPAR-α, PPAR
- Published
- 2018
39. Development and Evaluation of a Rapid Detection Technology of Streptococcus Pneumoniae Isolates from Specimen without Culture Based on LAMP and Bioinformatics
- Author
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Wen Jing Yu, Jiao Jiao Liu, Xiao Mei Zhang, Ming Cheng Li, and Yu Li
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biology ,business.industry ,Autolysin ,Loop-mediated isothermal amplification ,General Medicine ,medicine.disease_cause ,medicine.disease ,biology.organism_classification ,respiratory tract diseases ,Microbiology ,Pneumonia ,Otitis ,Streptococcus pneumoniae ,medicine ,medicine.symptom ,business ,Meningitis ,Pathogen ,Bacteria - Abstract
Streptococcus pneumoniae (S. pneumoniae) was one common pathogen that caused pneumonia, meningitis, otitis media, and sepsis. The traditional culture methods costed long time and omission often existed. A new method was developed based on Loop-mediated Isothermal Amplification (LAMP). A series of primers of autolysin (lytA) from S. pneumoniae were designed with specific primers soft, and set up LAMP system in detection of S. pneumoniae. Comparison of specificity and sensitivity results with culture and PCR method in 50 samples collected from patients with respiratory infections. The data demonstrated that the selected primers and reaction system in LAMP were respond to S. pneumoniae,not cross reacted to others bacteria. The detection of sensitivity to LAMP was 102CFU/mL. All of clinical specimens in the test, 9 cases (18.0%) were confirmed to be positive as S. pneumoniae,whereas, only 4(8.0%) were diagnosed by culture method. The LAMP technology has a specific, simple and accurate characteristic in differentiation S. Pneumoniae from clinical specimen.
- Published
- 2014
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40. Research for PV Cell and Storage Battery of Dynamic Economic Dispatch in Micro-Grid
- Author
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Zhi Jie Wang, Jiao Jiao Liu, Yi Zhi Ye, and Zhen Hai Zhang
- Subjects
Battery (electricity) ,Engineering ,education.field_of_study ,Operations research ,business.industry ,Population ,Photovoltaic system ,General Engineering ,Economic dispatch ,Grid ,Reliability engineering ,Genetic algorithm ,Electricity ,business ,education ,Operating cost - Abstract
The method of day-ahead dynamic economic dispatch is applied to the micro-grid composed of photovoltaic (PV) generation system and batteries to make its operational cost minimized. The battery life was converted cost and added to the objective function. Micro-grid’s mathematical model of economic dispatch was set up. Mathematical model of economic dispatch was solved by using the method of real population genetic algorithm. The charge and discharge plan of battery in micro-grid and buying or selling electricity plan between micro-grid and State Grid was established at the same time. Taking real data of Shanghai Electric Group’s micro-grid for case study, the dynamic economic dispatch is compared with traditional dispatch strategy. The results verify the effectiveness of the dynamic economic.
- Published
- 2014
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41. The Motor Temperature Rise Test System Based on Magnetic Powder Dynamometer
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Chang Chun Chi, Shi Liang Shao, Zhen Hai Zhang, Jiao Jiao Liu, and Zheng Bing Lian
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Engineering ,Software ,Data acquisition ,Dynamometer ,business.industry ,Motor testing ,General Engineering ,business ,Simulation ,Power (physics) ,Test (assessment) ,Magnetic powder - Abstract
The motor temperature rise is an important indicator for the evaluation of motor performance and the development of motor testing system put forward higher requirements to data acquisition and processing. In view of this, the motor temperature rise test system based on the magnetic power dynamometer which acted as a load was studied. The overall structure and the software algorithm of the system were introduced. The existing synchronous sampling method was put into use in data acquisition system of the motor temperature rise test so that it can automatically test the motor temperature rise. Combining with the instance, proves the accuracy of this method. This method has the superiority of reducing errors and improving accuracy by combining with the instance.
- Published
- 2014
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42. Research for Smart Micro-Grid System of Optimal Operation on the Island
- Author
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Yi Zhi Ye, Zhen Hai Zhang, Jiao Jiao Liu, and Zhi Jie Wang
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Mathematical optimization ,Engineering ,business.industry ,Genetic algorithm ,General Engineering ,Economic dispatch ,New energy ,Micro grid ,Geodetic datum ,business ,Energy system ,Simulation ,Renewable energy - Abstract
The paper introduces the advantage of the application of new energy generation, and then describes the structure of a smart micro-grid system built on an island which includes wind, solar, tidal-wave energy system. The method of day-ahead optimal operation was applied to smart micro-grid system on the island to minimize the operation cost by using genetic algorithm. Taking actual datum of Shanghai Electric Group’s micro-grid for case study, the dynamic economic dispatch is compared with traditional dispatch strategy. The results verify the effectiveness of the dynamic economic.
- Published
- 2014
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43. Effect of Toona sinensis Fruit Peel and Axal Region on the Development and Fecundity of Drosophila melanogaster
- Author
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Juan, Wang, primary, Jing-Xia, Yang, additional, Yun-Tao, Ji, additional, Hai-Jun, Zhao, additional, Ya-Wei, Tang, additional, Jiao-Jiao, Xu, additional, Jiao-Jiao, Liu, additional, and Chang-Qing, Qu, additional
- Published
- 2018
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44. Cause Analysis of Leakage of Supercritical (Ultra-Supercritical) Boiler Water Wall Slag Screen Pipe
- Author
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Jiao-jiao, Liu, primary, Liang, Xiong, additional, Ke-yang, Wan, additional, and Zhi, Cao, additional
- Published
- 2018
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45. A modified Johnson Cook model for elevated temperature flow behavior of T24 steel
- Author
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Jun–Ying Duan, Xiao-Feng Wang, Jiao–Jiao Liu, and Hong–Ying Li
- Subjects
Materials science ,Yield (engineering) ,Viscoplasticity ,Mechanical Engineering ,technology, industry, and agriculture ,Strain rate ,Flow stress ,Strain hardening exponent ,Condensed Matter Physics ,Stress (mechanics) ,Mechanics of Materials ,Dynamic recrystallization ,General Materials Science ,Composite material ,Deformation (engineering) - Abstract
The isothermal hot compression tests were carried out on Gleeble-3500 thermo mechanical simulator in the temperature range of 1323–1473 K and strain rates of 0.01 s−1, 0.1 s−1, 1 s−1 and 10 s−1. Based on the experimental results, a modified Johnson Cook model is proposed to describe the flow behavior of T24 steel. The modified model considers not only the yield and strain hardening portion of the original model but also the coupled effects of strain and temperature, and of strain rate and temperature on the flow behaviors. The high temperature deformation behavior of T24 steel was characterized based on the analysis of the stress-strain curves. The results showed that the flow stress predicted by the proposed model agrees well with the experimental stress, which validates the efficiency of the modified model in describing the deformation behavior of the steel. The true stress–true strain curves exhibit a peak stress at a very small strain, after which the flow stresses decrease until high strains, showing a typical dynamic recrystallization (DRX) behavior of the steel under the deformation conditions of lower strain rates.
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- 2013
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46. Effect of quenching process on mechanical properties and ductile-brittle transition behavior of 28CrMnMoV steel
- Author
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Yang-Hua Li, Xiao-Feng Wang, Hongying Li, Pei-lu Xiao, and Jiao-Jiao Liu
- Subjects
Quenching ,Austenite ,Materials science ,Brittleness ,Scientific method ,Transition temperature ,Metallic materials ,Metallurgy ,Metals and Alloys ,General Engineering ,Tempering ,Composite material ,Microstructure - Abstract
Effect of quenching process on the microstructure and mechanical properties of a kind of seamless tubes of steel 28CrMnMoV was investigated. Then, an investigation on the influence of two different quenching processes on the ductile-brittle transition behavior of this steel was undertaken. The ductile-brittle transition temperatures of the steel by two different quenching processes were also determined. The results show that a good combination of mechanical properties can be obtained through austenitizing experimental steel at 800 °C or 890 °C followed by tempering at 630 °C. Ductile-to-brittle transition temperature of 28CrMnMoV steel austenitized at 800 °C followed by tempering at 640 °C is about −73 °C, which is much lower than the value −37 °C when the steel was austenitized at 890°C and then tempered at 650 °C. This indicates that subcritical quenching process could decrease largely the ductile-to-brittle transition temperature of 28CrMnMoV steel.
- Published
- 2013
- Full Text
- View/download PDF
47. Time–temperature–property curves for quench sensitivity of 6063 aluminum alloy
- Author
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Jiao-jiao Liu, Cui-ting Zeng, Xiao-chao Lu, Mao-sheng Han, and Hong-ying Li
- Subjects
Quenching ,Materials science ,Precipitation (chemistry) ,Metallurgy ,Alloy ,Metals and Alloys ,Analytical chemistry ,Nucleation ,Atmospheric temperature range ,engineering.material ,Geotechnical Engineering and Engineering Geology ,Condensed Matter Physics ,Residual stress ,Phase (matter) ,Materials Chemistry ,engineering ,6063 aluminium alloy - Abstract
The quench sensitivity of 6063 alloy was investigated via constructing time−temperature−property (TTP) curves by interrupted quenching technique and transmission electron microscopy (TEM) analysis. The results show that the quench sensitivity of 6063 alloy is lower than that of 6061 or 6082 alloy, and the critical temperature ranges from 300 to 410 °C with the nose temperature of about 360 °C. From TEM analysis, heterogeneous precipitate β-Mg2Si is prior to nucleate on the (AlxFeySiz) dispersoids in the critical temperature range, and grows up most rapidly at the nose temperature of 360 °C. The heterogeneous precipitation leads to a low concentration of solute, which consequently reduces the amount of the strengthening phase β'' after aging. In the large-scale industrial production of 6063 alloy, the cooling rate during quenching should be enhanced as high as possible in the quenching sensitive temperature range (410−300 °C) to suppress the heterogeneous precipitation to get optimal mechanical properties, and it should be slowed down properly from the solution temperature to 410 °C and below 300 °C to reduce the residual stress.
- Published
- 2013
- Full Text
- View/download PDF
48. Application of Data Fusion Based on Genetic Algorithm and BP Neural Network in WSN
- Author
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Jiao Jiao Liu, Zhao Xiang Li, and Yi Xu
- Subjects
Engineering ,Artificial neural network ,Mean squared error ,business.industry ,General Engineering ,Initialization ,Sensor fusion ,computer.software_genre ,Convergence (routing) ,Genetic algorithm ,Data mining ,Routing (electronic design automation) ,business ,computer ,Energy (signal processing) - Abstract
Energy-saving is one of the inevitable problems of the routing design in WSN, while Data Fusion technology is widely utilized in energy constraint WSN to reduce the amount of messages exchanged between sensor nodes. This paper proposes a new algorithm based on Integrated Genetic and BP Neural Network(IGBP), IGBP uses the global search capability of GA to remedy the deficiency of BP artificial neural network. First, IGBP generates the best individuals in different networks by GA algorithm. Then it chooses the most optimize individual measure by Mean Squared Error to construct the BP network which was supplied to train of the WSN. Using the optimize individual nodes as initialization value training the BP network, it will enhance the learning rates of convergence and avoid falling into the local minimums .The simulation results show that the IGBP algorithm has made great progress in balancing the consumption of energy so as to prolong the network lifetime.
- Published
- 2012
- Full Text
- View/download PDF
49. Constitutive equation to predict elevated temperature flow stress of V150 grade oil casing steel
- Author
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Hongying Li, Dong-Dong Wei, Jiao-Jiao Liu, Xiao-Feng Wang, and Yang-Hua Li
- Subjects
Materials science ,Mechanical Engineering ,Constitutive equation ,Flow stress ,Strain rate ,Condensed Matter Physics ,Compression (physics) ,Isothermal process ,Stress (mechanics) ,Mechanics of Materials ,General Materials Science ,Deformation (engineering) ,Composite material ,Casing - Abstract
The true stress–strain data from isothermal hot compression tests, in a wide range of temperatures (1173–1473 K) and strain rates (0.01–10 s −1 ), were employed to study the deformation behavior and develop constitutive equation of V150 grade oil casing steel based on an Arrhenius-type equation. The flow stress increases with the decrease of deformation temperature and the increase of strain rate, which can be represented by Zener–Hollomon parameter in an exponential equation. The influence of strain was incorporated in the developed constitutive equation by considering the effect of strain on material constants. The flow stress predicted by the constitutive equation shows good agreement with the experimental value through the whole experimental temperature and strain rate range except a slight deviation for predicting the stress deformed at 1173 K under 0.01 s −1 , and the average relative error is 4.21%.
- Published
- 2011
- Full Text
- View/download PDF
50. The Effect of Y on Aging Response and Mechanical Properties of Mg-Ho-Zr Alloys
- Author
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Zhi Zhang, Jian Li Wang, Jiao Jiao Liu, Bao Qing Zhang, and Bao Zhong Liu
- Subjects
Materials science ,Mechanical Engineering ,Metallurgy ,Alloy ,engineering.material ,Condensed Matter Physics ,Microstructure ,Casting ,Grain size ,Precipitation hardening ,Mechanics of Materials ,Phase (matter) ,Ultimate tensile strength ,Vickers hardness test ,engineering ,General Materials Science - Abstract
Mg-10Ho-0.6Zr alloys with different amount of Y additions are prepared by metal mould casting method. The effects of Y content on microstructure, age hardening behavior and mechanical properties are investigated. Results show that all the as-cast Mg-10Ho-xY-0.6Zr alloys are mainly comprised of α-Mg matrix and Mg24(Ho,Y)5phase. With increasing Y content, grain size of the as-cast alloys is reduced. Age hardening response, Vickers hardness and mechanical properties are improved with the addition of Y. The maximum ultimate tensile strength (UTS) and yield strength (YS) are obtained in Mg-10Ho-3Y-0.6Zr alloy at peak-aged state, and the values are 215 MPa, 158 MPa at room temperature, and 144 MPa, 126 MPa at 250 °C, respectively. The improvement of the UTS is mainly attributed to the fine distributed quadrate-like β stable phase. Key words: Mg-Ho-Y-Zr alloy; Microstructure; Age hardening behavior; Mechanical properties
- Published
- 2011
- Full Text
- View/download PDF
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