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218 results on '"Jiang, Ruhong"'

2. Dose adjustment of paroxetine based on CYP2D6 activity score inferred metabolizer status in Chinese Han patients with depressive or anxiety disorders: a prospective study and cross-ethnic meta-analysis

Author

Liao, Yundan, Sun, Yutao, Guo, Jing, Kang, Zhewei, Sun, Yaoyao, Zhang, Yuyanan, Bai, Hanping, Hu, Maolin, Li, Bing, Han, Jingshan, Xiang, Jiaojiao, Jiang, Ruhong, Zhang, Jian, He, Yuxiang, Yang, Huailiang, Liu, Guifang, Peng, Lili, Yu, Hui, Cheng, Xialong, Fang, Wenmei, Zheng, Rongyan, Lin, Ruiqian, Zhai, Xiao-yan, Tang, Rui, Deng, Fangyi, Zhu, Chunyan, Zhang, Ting, Yang, Yan, Geng, Ji-ting, Wu, Di, Chen, Yi-huan, Sun, Yifan, Zhou, Yong-can, Wang, Wei-xin, Zhang, Jian-min, Wang, Jun, Wang, Hua-ning, Chen, Zhi-yu, Wang, Kai, Pan, Jiyang, Ni, Ai-hua, Weng, Saizheng, Wang, Anzhen, Cao, Changbin, Sun, Lidong, Zhang, Yong, Kuang, Li, Zhang, Yunshu, Liu, Zhongchun, Yue, Weihua, He, Jiong, Huang, Chengchen, and Sun, Xin

Published
2024
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12. Respiratory control minimizes diaphragmatic contraction and dry cough during pulsed-field ablation of atrial fibrillation

Author

Jiang, Ruhong, primary, Liu, Qiang, additional, Chen, Laite, additional, Chen, Shiquan, additional, Wang, Yunhe, additional, Cheng, Hui, additional, Sheng, Xia, additional, Sun, Yaxun, additional, Yu, Lu, additional, Zhang, Pei, additional, Lin, Jianwei, additional, Zhang, Zuwen, additional, Ding, Xueyan, additional, Shehata, Michael, additional, Fu, Guosheng, additional, and Jiang, Chenyang, additional

Published
2023
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13. Left atrial appendage occlusion using the LAmbre device in atrial fibrillation patients with a history of ischemic stroke: 1‐Year outcomes from a multicenter study in China

Author

Bangash, Abdul Basit, primary, Li, Yuechun, additional, Huang, Weijian, additional, Zhong, Jingquan, additional, Zheng, Hongmei, additional, Zhang, Dayong, additional, Zeng, Anning, additional, Wang, Rui, additional, Zhao, Wenbiao, additional, Wang, Maojing, additional, Zhao, Yu, additional, Yu, Lu, additional, Liu, Qiang, additional, Jiang, Ruhong, additional, Jiang, Chenyang, additional, and Zhang, Jinhua, additional

Published
2023
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16. Intracardiac echocardiography guided electrified J‐wire trans‐septal puncture: A prospective randomized controlled trial.

Author

Cheng, Hui, Bangash, Abdul Basit, Tao, Yuhang, Jiang, Ruhong, Liu, Qiang, Cheng, Cheng, Fu, Guosheng, and Jiang, Chenyang

Subjects
PATIENT safety, STATISTICAL sampling, MAGNETIC resonance imaging, TREATMENT effectiveness, DESCRIPTIVE statistics, OPERATIVE surgery, LONGITUDINAL method, ATRIAL fibrillation, CATHETER ablation, COMPARATIVE studies, ECHOCARDIOGRAPHY, TIME
Abstract

Background: Application of electrocautery to a J‐wire is used to perform transseptal puncture (TSP), but with limited evidence supporting safety and efficacy. We conducted a prospective randomized controlled trial to evaluate the safety and efficacy of this technique. Methods: Two hundred consecutive patients were randomized in a 1:1 fashion to either the ICE‐guided electrified J‐wire TSP group or a conventional Brockenbrough (BRK) needle TSP group. The TSP was performed with a 0.032″ guidewire under 20 W, "coag" mode and was compared to TSP using the BRK needle. The primary safety endpoints were complications related to TSP. The primary efficacy endpoints included the TSP success rate, the total TSP time, and the total procedure time. Results: All patients complete the procedure safely. The electrified J‐wire TSP group had a significantly shorter TSP time than BRK needle TSP group. The total procedure time, number of TSP attempts required to achieve successful LA access, width of the intra‐atrial shunt at the end of ablation were similar between the two groups. The incidence of new cerebral infarction detected by MRI were similar between the two groups (3/32 patients in the J‐wire TSP group and 2/26 patients in conventional BRK TSP group, p =.82). And no difference in the incidence of residual intra‐atrial shunt (4.3% vs. 6%, p =.654) during the 3‐month's follow up. Conclusion: Using an electrified J‐wire for TSP under the guidance of ICE appears to be as safe as and more efficient than conventional BRK needle TSP, which may be especially useful in the era of non‐fluoroscopy AF ablation. [ABSTRACT FROM AUTHOR]

Published
2024
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17. Chinese expert consensus on the construction of the fluoroless cardiac electrophysiology laboratory and related techniques

Author

Jiang, Chenyang, primary, Ma, Changsheng, additional, Chen, Songwen, additional, Chen, Shiquan, additional, Jiang, Chenxi, additional, Jiang, Ruhong, additional, Ju, Weizhu, additional, Long, Deyong, additional, Li, Ding, additional, Li, Jia, additional, Liu, Qiang, additional, Ma, Wei, additional, Pu, Xiaobo, additional, Wang, Rui, additional, Wang, Yuegang, additional, Yi, Fu, additional, Zou, Cao, additional, Zhang, Jidong, additional, Zhang, Xi, additional, Zhao, Yujie, additional, Zei, Paul C., additional, Biase, Luigi Di, additional, Chang, Dong, additional, Cai, Heng, additional, Chen, Lianghua, additional, Chen, Minglong, additional, Fu, Guosheng, additional, Fu, Hua, additional, Fan, Jie, additional, Gui, Chun, additional, Jiang, Tingbo, additional, Liu, Shaowen, additional, Li, Xuebin, additional, Li, Yigang, additional, Shu, Maoqin, additional, Wang, Yan, additional, Xu, Jian, additional, Xie, Ruiqin, additional, Xia, Yunlong, additional, Xue, Yumei, additional, Yang, Pingzhen, additional, Yuan, Yiqiang, additional, Zhong, Jingquan, additional, and Zhu, Wenqing, additional

Published
2023
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18. Dopamine Genes and Nicotine Dependence in Treatment-Seeking and Community Smokers

Author

Bergen, Andrew W, Conti, David V, Van Den Berg, David, Lee, Wonho, Liu, Jinghua, Li, Dalin, Guo, Nan, Mi, Huaiyu, Thomas, Paul D, Lessov-Schlaggar, Christina N, Krasnow, Ruth, He, Yungang, Nishita, Denise, Jiang, Ruhong, McClure, Jennifer B, Tildesley, Elizabeth, Hops, Hyman, Tyndale, Rachel F, Benowitz, Neal L, Lerman, Caryn, and Swan, Gary E

Subjects
Biological Psychology, Pharmacology and Pharmaceutical Sciences, Biomedical and Clinical Sciences, Psychology, Tobacco Smoke and Health, Drug Abuse (NIDA only), Substance Misuse, Tobacco, Brain Disorders, Genetics, Clinical Research, Prevention, Good Health and Well Being, Adult, Analysis of Variance, Bupropion, Cohort Studies, DNA-Binding Proteins, Dopamine Plasma Membrane Transport Proteins, Dopamine Uptake Inhibitors, Female, Genetic Predisposition to Disease, Genotype, Humans, Linkage Disequilibrium, Male, Middle Aged, Nuclear Receptor Subfamily 4, Group A, Member 2, Polymorphism, Single Nucleotide, Receptors, Dopamine D3, Residence Characteristics, Smoking, Tobacco Use Disorder, Transcription Factors, White People, dopamine transporter, Fagerstrom Test for Nicotine Dependence, single nucleotide polymorphism, candidate gene, gene-gene interaction, Medical and Health Sciences, Psychology and Cognitive Sciences, Psychiatry, Neurosciences, Biological psychology
Abstract

We utilized a cohort of 828 treatment-seeking self-identified white cigarette smokers (50% female) to rank candidate gene single nucleotide polymorphisms (SNPs) associated with the Fagerström Test for Nicotine Dependence (FTND), a measure of nicotine dependence which assesses quantity of cigarettes smoked and time- and place-dependent characteristics of the respondent's smoking behavior. A total of 1123 SNPs at 55 autosomal candidate genes, nicotinic acetylcholine receptors and genes involved in dopaminergic function, were tested for association to baseline FTND scores adjusted for age, depression, education, sex, and study site. SNP P-values were adjusted for the number of transmission models, the number of SNPs tested per candidate gene, and their intragenic correlation. DRD2, SLC6A3, and NR4A2 SNPs with adjusted P-values

Published
2009

20. Haplotype Variation and Linkage Disequilibrium in 313 Human Genes

Author

Stephens, J. Claiborne, Schneider, Julie A., Tanguay, Debra A., Choi, Julie, Acharya, Tara, Stanley, Scott E., Jiang, Ruhong, Messer, Chad J., Chew, Anne, Han, Jin-Hua, Duan, Jicheng, Carr, Janet L., Lee, Min Seob, Koshy, Beena, Kumar, A. Madan, Zhang, Ge, Newell, William R., Windemuth, Andreas, Xu, Chuanbo, Kalbfleisch, Theodore S., Shaner, Sandra L., Arnold, Kevin, Schulz, Vincent, Drysdale, Connie M., Nandabalan, Krishnan, Judson, Richard S., Ruaño, Gualberto, and Vovis, Gerald F.

Published
2001

22. Respiratory control minimizes diaphragmatic contraction and dry cough during pulsed-field ablation of atrial fibrillation.

Author

Jiang, Ruhong, Liu, Qiang, Chen, Laite, Chen, Shiquan, Wang, Yunhe, Cheng, Hui, Sheng, Xia, Sun, Yaxun, Yu, Lu, Zhang, Pei, Lin, Jianwei, Zhang, Zuwen, Ding, Xueyan, Shehata, Michael, Fu, Guosheng, and Jiang, Chenyang

Abstract

Aims Pulsed-field ablation (PFA) is a promising new ablation modality to treat atrial fibrillation. However, PFA can cause varying degrees of diaphragmatic contraction and dry cough, especially under conscious sedation. This prospective study presents a method to minimize the impact of PFA on diaphragmatic contraction and dry cough during the procedure. Methods and results Twenty-eight patients underwent PFA for pulmonary vein (PV) and superior vena cava isolation under conscious sedation. Each patient received two groups of ablations in each vein: the control group allowed PFA application during any phase of respiratory cycle, while the test group used respiratory control, delivering PFA energy only at the end of expiration. A rating score system was developed to assess diaphragmatic contraction and dry cough. A total of 1401 control ablations and 4317 test ablations were performed. The test group had significantly lower scores for diaphragmatic contraction (P < 0.01) and dry cough (P < 0.001) in all PVs compared to the control group. The average relative reductions in scores for all PVs were 33–47% for diaphragmatic contraction and 67–83% for dry cough. The percentage of ablations with scores ≧2 for diaphragmatic contraction decreased significantly from 18.5–28.0% in the control group to 0.4–2.6% in the test group (P < 0.001). For dry cough, the percentage decreased from 11.9–43.7% in the control group to 0.7–2.1% in the test group. Conclusion Pulsed-field ablation application at the end of expiration can reduce the severity of diaphragmatic contraction and eliminate moderate and severe dry cough during PV isolation performed under conscious sedation. [ABSTRACT FROM AUTHOR]

Published
2024
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26. Intracardiac echocardiography is a safe and effective alternative to transesophageal echocardiography for left atrial appendage thrombus evaluation at the time of atrial fibrillation ablation: The ICE‐TEE study

Author

Wang, Yuxing, primary, Zhao, Yi, additional, Zhou, Kuangshi, additional, Zei, Paul C., additional, Wang, Yunhe, additional, Cheng, Hui, additional, Chen, Shiquan, additional, Tao, Yuhang, additional, Mao, Yankai, additional, Liu, Qiang, additional, Bangash, Abdul Basit, additional, Sheng, Xia, additional, Sun, Yaxun, additional, Zhang, Pei, additional, Yu, Lu, additional, Lin, Jianwei, additional, Zhang, Zuwen, additional, Fu, Guosheng, additional, Jiang, Ruhong, additional, and Jiang, Chenyang, additional

Published
2022
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27. Efficacy of ablation index‐guided pulmonary vein isolation in patients with paroxysmal atrial fibrillation

Author

Jiang, Ruhong, primary, Chen, Minglong, additional, Fan, Jie, additional, Yi, Fu, additional, Tang, Anli, additional, Liu, Xingpeng, additional, Zhu, Wenqing, additional, Liu, Shaowen, additional, Huang, Xiaobo, additional, Liu, Qiang, additional, Ju, Weizhu, additional, Zhang, Xi, additional, Li, Jie, additional, He, Jiangui, additional, Shi, Liang, additional, Zhou, Genqing, additional, Wang, Yuegang, additional, Fu, Guosheng, additional, and Jiang, Chenyang, additional

Published
2022
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33. PO-06-183 PAROXYSMAL ATRIAL FIBRILLATION TREATED BY A PULSED- FIELD ABLATION SYSTEM USING A CIRCULAR CATHETER WITH VARIABLE DIAMETER （ONE-YEAR OUTCOME OF PF-BEAT-AF CLINICAL TRIAL）

Author

Liu, Qiang, Jiang, Ruhong, Yin, Xiaomeng, Xiao, Fangyi, WANG, YUEGANG, Ju, Weizhu, Hu, Hongde, Zhang, Jidong, Li, Jun, Li, Ruibin, Yu, Lu, Cheng, Hui, Li, Jianyong, Li, Xinzhong, Jiang, Xiaohong, CHEN, HONGWU, Liu, Hailei, Wang, Zidun, Li, Yan, Chen, Minglong, and jiang, chenyang

Published
2024
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35. Selective Interventricular Septal Radiofrequency Ablation in Patients With Hypertrophic Obstructive Cardiomyopathy: Who Can Benefit?

Author

Liu, Qiang, primary, Qiu, Hangyuan, additional, Jiang, Ruhong, additional, Tang, Xiaomei, additional, Guo, Wenpu, additional, Zhou, Kuangshi, additional, Chen, Qiufan, additional, Sun, Yaxun, additional, Yu, Lu, additional, Chen, Shiquan, additional, Zhang, Pei, additional, Sheng, Xia, additional, Zhu, Jun, additional, Lin, Jianwei, additional, Cheng, Hui, additional, Wang, Yunhe, additional, Wang, Bei, additional, Yu, Chan, additional, Mao, Yankai, additional, Zhang, Juhong, additional, Zhang, Zuwen, additional, Zei, Paul C., additional, Fu, Guosheng, additional, and Jiang, Chenyang, additional

Published
2021
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37. Intracardiac echocardiography is a safe and effective alternative to transesophageal echocardiography for left atrial appendage thrombus evaluation at the time of atrial fibrillation ablation: The ICE‐TEE study.

Author

Wang, Yuxing, Zhao, Yi, Zhou, Kuangshi, Zei, Paul C., Wang, Yunhe, Cheng, Hui, Chen, Shiquan, Tao, Yuhang, Mao, Yankai, Liu, Qiang, Bangash, Abdul Basit, Sheng, Xia, Sun, Yaxun, Zhang, Pei, Yu, Lu, Lin, Jianwei, Zhang, Zuwen, Fu, Guosheng, Jiang, Ruhong, and Jiang, Chenyang

Subjects
ATRIAL fibrillation treatment, ECHOCARDIOGRAPHY, THROMBOSIS, LENGTH of stay in hospitals, FEVER, TRANSESOPHAGEAL echocardiography, TIME, CATHETER ablation, MEDICAL screening, RETROSPECTIVE studies, DISEASE incidence, COMPARATIVE studies, DESCRIPTIVE statistics, RESEARCH funding, ORGANIZATIONAL effectiveness, SENSITIVITY & specificity (Statistics), LEFT heart atrium, EVALUATION
Abstract

Background: Intracardiac echocardiography (ICE) technology has been increasingly accepted as an integral part of atrial fibrillation (AF) ablation procedures. It is still unknown whether ICE can routinely replace transesophageal echocardiography (TEE) for routine thrombus screening in non‐selective AF patients. Objective: To assess whether ICE can routinely replace TEE in screening for left atrial (LA)/left atrial appendage (LAA) thrombus in general patients undergoing catheter ablation for AF. Methods: A total of 2003 consecutive patients undergoing AF ablation were included. 1155 patients (ICE group) received intra‐procedural ICE examination for LA/LAA thrombus screening, while 848 patients (TEE group) received pre‐procedure TEE examination. The incidence of thrombus, peri‐procedure complications, and hospital efficiency were assessed. Results: The LA and LAA were adequately visualized in all patients. Five patients in the ICE group and 15 patients in the TEE group were found to have LAA thrombus. The incidence of major periprocedural thrombo‐embolic events was comparable between two groups (0.2% vs. 0.1%, p =.76), none were due to undetected LA/LAA thrombus. Other major periprocedural complications occurred at similar rates in both groups, while post‐procedure fever was less common in the ICE group (12.7% vs. 17.4%, p <.001). Procedure times and hospital length of stay were both shorter in the ICE group (142 min [87–197 min] vs. 150 min [95–205 min], and 3[2–4] day vs. 4[3–5] day, respectively, both p <.001). Conclusions: ICE can replace TEE for atrial thrombus screening in AF patients undergoing ablation without increased complications. An "ICE replacing TEE" workflow can also reduce the incidence of postoperative fever and improve hospital efficiency. [ABSTRACT FROM AUTHOR]

Published
2023
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39. Rationale and Study Design for Evaluating the Efficacy and Safety of Intracardiac Echocardiography-Guided Minimal-Fluoroscopy Ablation in Patients with Paroxysmal Atrial Fibrillation

Author

Jiang, Ruhong, primary, Liu, Xingpeng, additional, Zhang, Jidong, additional, Chen, Yu, additional, Wang, Rui, additional, Wu, Mengzuo, additional, Long, Deyong, additional, Li, Jia, additional, Wang, Haixiong, additional, Fan, Jie, additional, Ju, Weizhu, additional, Ge, Weili, additional, Liu, Xu, additional, Deng, Hai, additional, Wang, Weijian, additional, Yang, Pingzhen, additional, Li, Ding, additional, Huang, Xiaobo, additional, Liu, Xiongtao, additional, Tao, Hailong, additional, Zei, Paul C., additional, Tung, Roderick, additional, Wang, Xunzhang, additional, and Jiang, Chenyang, additional

Published
2021
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43. First-Line Catheter Ablation of Monomorphic Ventricular Tachycardia in Cardiomyopathy Concurrent With Defibrillator Implantation: The PAUSE-SCD Randomized Trial.

Author

Tung, Roderick, Xue, Yumei, Chen, Minglong, Jiang, Chenyang, Shatz, Dalise Y., Besser, Stephanie A., Hu, Hongde, Chung, Fa-Po, Nakahara, Shiro, Kim, Young-Hoon, Satomi, Kazuhiro, Shen, Lishui, Liang, Er'peng, Liao, Hongtao, Gu, Kai, Jiang, Ruhong, Jiang, Jian, Hori, Yuichi, Choi, Jong-Il, and Ueda, Akiko

Published
2022
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47. Challenges and opportunities when transitioning from in vivogene replacement to in vivoCRISPR/Cas9 therapies – a spotlight on hemophilia

Author

Segurado, Oscar G, Jiang, Ruhong, and Pipe, Steven W

Abstract

ABSTRACTIntroductionCurrently, a few in vivogene replacement therapies are commercially available, with many in clinical development for the treatment of some inherited monogenic diseases. These disorders arise from mutations in genes encoding essential proteins with a well understood biological function. Wide adoption of gene replacement therapies requires solid safety and efficacy profiles with demonstrable long-term durability and cost-benefit advantages vs standard therapies.Areas coveredThis expert review outlines the challenges and opportunities in treating hemophilia, including the progression from in vivogene therapies toward in vivogene editing, focusing on pre-clinical and emerging clinical data for gene editing and addressing the need for sustained and durable gene expression during hepatocyte proliferation when the liver is unable to maintain steady gene expression and protein production.Expert opinionIn vivogene editing in liver tissues may be able to rescue patients younger than 18 years who are not eligible for gene replacement therapies, with hemophilia as a prime example.

Published
2022
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