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158 results on '"Jia, Liting"'

1. Rice Storage Proteins: Focus on Composition, Distribution, Genetic Improvement and Effects on Rice Quality

Author

Long Xinkang, Guan Chunmin, Wang Lin, Jia Liting, Fu Xiangjin, Lin Qinlu, Huang Zhengyu, and Liu Chun

Subjects
rice storage protein, composition, distribution, genetic improvement, rice quality, Plant culture, SB1-1110
Abstract

Rice storage proteins (RSPs) are plant proteins with high nutritional quality. As the second largest type of storage substance in rice, it is the main source of protein intake for people who consume rice as a staple food. The content and type of RSPs affect the appearance, processing quality and eating quality of rice. These effects involve the distribution of RSPs in rice grains as well as the interactions of RSPs with other components such as starch in rice grains. In the past two decades, some progress has been made in the genetic improvement of RSPs. However, the determination mechanism of protein content and composition in rice is still unclear, and the mechanism of the effect of RSPs on rice quality has not been elucidated. In this review, the composition, biosynthesis and distribution of RSPs, and quantitative trait loci mapping and cloning of RSP genes are summarized, the research progress of the influence of RSPs and their components on rice quality are reviewed, and the research directions in the future are proposed.

Published
2023
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5. Growth Patterns of Carbon Clusters Cn(n= 2–60) Identified via ABCluster Searching and DFT Benchmarking

Author

Jia, Liting, Wang, Yu, Tian, Xu, Wang, Siyu, Wang, Xiao, and Zhang, Meng

Abstract

Recently, novel algorithms and enhanced computational capabilities have created unprecedented opportunities to precisely determine the geometric structures of clusters through theoretical calculations. In this study, we extensively investigated and characterized the geometric arrangements of the carbon clusters Cn(n= 2–60), employing the efficient ABCluster algorithm in conjunction with the gradient-corrected PBE and higher-accuracy B3LYP hybrid functional in density functional theory (DFT). New structures and a discernible structural growth pattern have been discovered. We observed a distinct preference in carbon clusters that transform from the linear chains (n= 2–9) to closed single-ring and planar structures (n= 10–27) and finally evolve to carbon cages (n= 28–60). A shortcut to construct the cage clusters was unveiled by inserting or rotating specific atoms within a distinct structural unit. The research results obtained from combining ABCluster with DFT calculations offer valuable new insights into the growth mechanisms and evolutionary trajectories of carbon clusters, providing a crucial theoretical framework for the development of innovative carbon-based materials and their potential applications.

Published
2024
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19. Additional file 1 of Diagnostic value of a single β-hCG test in predicting reproductive outcomes in women undergoing cleavage embryo transfer: a retrospective analysis from a single center

Author

Zhang, Yuchao, Li, Zhen, Ren, Bingnan, Wu, Wenbin, Liu, Yanli, Wang, Xingling, Guan, Yichun, and Jia, Liting

Abstract

Additional file 1: Table S1. The women who gavelive birth but had the lowest β-hCG levels. Table S2.β-hCG levels based on the quality of single transferred embryo. Table S3. β-hCG levels based on thenumber of good quality embryo in women with two embryo. Table S4. β-hCG levels based on women age in two embryos group.

Published
2022
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33. Relationship between single-nucleotide polymorphisms in un-translated region of human leukocyte antigen-G and preeclampsia

Author

Zhang Linlin, Li Hong, Zhang Zhan, Jia Liting, and Zhang Nan

Subjects
Untranslated region, medicine.medical_specialty, Pharmaceutical Science, Single-nucleotide polymorphism, Human leukocyte antigen, Biology, medicine.disease, law.invention, Preeclampsia, Endocrinology, law, Internal medicine, Genotype, Immunology, medicine, SNP, Single-nucleotide polymorphisms, Human leukocyte antigen-G, Un-translated Region, Preeclampsia, Pharmacology (medical), Gene, reproductive and urinary physiology, Polymerase chain reaction
Abstract

Purpose: The aim of this study was to unravel the link between human leukocyte antigen-G untranslated region (HLA-G 3-UTR) single-nucleotide polymorphism (SNP) and preeclampsia by examining polymorphisms in HLA-G 3-UTR in preeclampsia patients and their newborns, as well as those of women with normal pregnancy and their newborns. Methods: Single pregnant mothers and their newborns at the Third Affiliated Hospital of Zhengzhou University, China, were divided into preeclampsia group (144 cases), and normal pregnancy group (122 cases). Blood samples from the two groups were collected for DNA extraction, and the DNA samples were analyzed for HLA-G 3'-UTR SNP by polymerase chain reaction (RT-PCR) and direct sequencing method. Results: The frequency of CG genotype in HLA-G 3-UTR 3127 gene in the preeclampsia group was significantly lower, while the frequency of AA genotype in HLA-G 3-UTR 3172 gene in the preeclampsia group was significantly higher ( p < 0.05) when compared with the normal pregnancy group. Furthermore, frequencies of the compatible genotype AA/AA (mothers/newborns) in HLA-G 3-UTR 3172 gene in the preeclampsia group were significantly higher relative to the normal pregnancy group ( p < 0.05). Conclusion: These results suggest that when CC/GG is the compatible genotype in HLA-G 3-UTR 3127 gene of mothers/newborns, preeclampsia risk may decrease, but it may increase if the compatible genotype is AA/AA. Thus, SNP in HLA-G 3-UTR 3127 gene may be a protective factor against preeclampsia in Chinese Han pregnant women, while SNP in 3172 gene may be associated with susceptibility to preeclampsia. Keywords: Single-nucleotide polymorphisms, Human leukocyte antigen-G, Un-translated Region, Preeclampsia

Published
2017

39. Gestational age-specific reference intervals for 15 biochemical measurands during normal pregnancy in China.

Author

Dai, Yanpeng, Yuan, Enwu, Jia, Liting, Liu, Junjie, Li, Yushan, Wang, Quanxian, Wang, Linkai, and Su, Yanhua

Subjects
GESTATIONAL age, PROGESTERONE, ESTROGEN, PREGNANCY, ALKALINE phosphatase, GLOMERULAR filtration rate, URIC acid, BIOCHEMISTRY, KIDNEY function tests, LIVER function tests, PHENOMENOLOGY, PREGNANT women, REFERENCE values, CROSS-sectional method
Abstract

Aims Physiological changes that occur during pregnancy can influence biochemical parameters. Therefore, using reference intervals based on specimens from non-pregnant women to interpret laboratory results during pregnancy may be inappropriate. This study aimed to establish the essential reference intervals for a range of analytes during pregnancy. Methods A cross-sectional study was performed in 13,656 healthy pregnant and 2634 non-pregnant women. Fifteen biochemical measurands relating to renal and hepatic function were analysed using an Olympus AU5400 analyzer (Olympus, Tokyo, Japan). All the laboratory results were checked for outliers using Dixon's test. Reference intervals were established using a non-parametric method. Results Alanine aminotransferase, aspartate aminotransferase, albumin, cholinesterase, creatinine, direct bilirubin, gamma-glutamyl transpeptidase, total bilirubin, total bile acid and total protein showed a decrease during the whole gestational period, while alkaline phosphatase and uric acid increased. Urea nitrogen, β2-microglobulin and cystatin-C fell significantly during the first trimester and then remained relatively stable until third trimester. Reference intervals of all the measurands during normal pregnancy have been established. Conclusions The reference intervals established here can be adopted in other clinical laboratories after appropriate validation. We verified the importance, for some measurands, of partitioning by gestational age when establishing reference intervals during pregnancy. [ABSTRACT FROM AUTHOR]

Published
2018
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49. Differential expression of beta-catenin and dickkopf-1 in the third trimester placentas from normal and preeclamptic pregnancies: a comparative study.

Author

Zhan Zhang, He Li, Linlin Zhang, Jia, Liting, and Peng Wang

Subjects
CATENINS, THIRD trimester of pregnancy, PLACENTA, COMPARATIVE studies, WNT proteins, CELLULAR signal transduction, PREECLAMPSIA, CESAREAN section
Abstract

Background: Beta-catenin is a key nuclear effector of Wnt signaling which could be antagonized by dickkopf-1 (DKK1). Beta-catenin and DKK1 are involved in a variety of biological processes; however, their expression in the placenta with severe preeclampsia (PE) has not been elucidated. This study was aimed to detect the localization and compare the expression of beta-catenin and DKK1 in normal and preeclamptic placenta. Methods: Sixty pregnant women who underwent cesarean section were enrolled in this study, including 30 healthy pregnant women in the control group and 30 preeclamptic women in the severe PE group. Real-time polymerase chain reaction (real-time-PCR) and western blot were employed to detect the beta-catenin and DKK1 mRNA and protein expression levels, respectively, and their locations were evaluated by immunohistochemistry (IHC). Results: Our results indicated that beta-catenin and DKK1 were expressed predominantly in the syncytiotrophoblast and the extravillous trophoblast (EVT). The beta-catenin mRNA and protein expressions were significantly decreased, whereas the DKK1 significantly increased in preeclamptic placental tissues compared to normal placental controls. Conclusions: In conclusion, decreased beta-catenin expression, as well as DKK1 over-expression might be associated with the process of the pathogenesis of PE. Further studies would elucidate their exact roles in the pathogenesis of PE. [ABSTRACT FROM AUTHOR]

Published
2013
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50. Variant analysis of PEX11B gene from a family with peroxisome biogenesis disorder 14B by whole exome sequencing.

Author

Tian, Yuan, Zhang, Linlin, Li, Ying, Gao, Jinshuang, Yu, Haiyang, Guo, Yaqing, and Jia, Liting

Subjects
RECESSIVE genes, GENE families, ORGANELLE formation, DISABILITIES, BIOINFORMATICS software, JUVENILE diseases
Abstract

Background: Peroxisome biogenesis disorder 14B (PBD14B) is an autosomal recessive peroxisome biogenesis disorder characterized clinically by mild intellectual disability, congenital cataracts, progressive hearing loss, and polyneuropathy peroxisome biogenesis disorders are genetically heterogeneous group of disorders caused by biallelic mutations in peroxin (PEX) genes. Methodology/Laboratory Examination: DNA of the family was extracted and sequenced by whole exome sequencing. The results were validated with Sanger sequencing analyzed with Bioinformatics software. Results: Sequencing result showed that the patient has carried a homozygous variant of c.277C>T of the PEX11B gene. The patient's brother has carried a homozygous variant of c.277C>T of the PEX11B gene and their variants of c.277C>T of the PEX11B gene were inherited, respectively, from his mother and father. Discussion and Conclusion: The homozygous variant of c.277C>T of the PEX11B gene probably underlie the disease in this child and her brother. [ABSTRACT FROM AUTHOR]

Published
2020
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