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2 results on '"Jessamine Tsan-Hsiang Chen"'

1. Improving mental health and social participation outcomes in older adults with depression and anxiety: Study protocol for a randomised controlled trial.

Author

Jessamine Tsan-Hsiang Chen, Viviana M Wuthrich, Ronald M Rapee, Brian Draper, Henry Brodaty, Henry Cutler, Lee-Fay Low, Andrew Georgiou, Carly Johnco, Michael Jones, Denise Meuldijk, and Andrew Partington

Subjects
Medicine, Science
Abstract

BackgroundIncreasing both the frequency and quality of social interactions within treatments for anxiety and depressive disorders in older adults may improve their mental health outcomes and quality of life. This study aims to evaluate the clinical efficacy and cost utility of an enhanced cognitive behavioural therapy (CBT) plus social participation program in a sample of older adults with depression and/or anxiety.MethodsA total of 172 community-dwelling adults aged 65 years or older with an anxiety and/or depressive disorder will be randomly allocated to either an enhanced CBT plus social participation program (n = 86) or standard CBT (n = 86). Both treatments will be delivered during 12 weekly individual sessions utilising structured manuals and workbooks. Participants will be assessed at pre-treatment, post-treatment, and 12-month follow-up. The primary outcome evaluates mean change in clinician-rated diagnostic severity of anxiety and depressive disorders from baseline to post-treatment (primary endpoint) based on a semi-structured diagnostic interview. Secondary outcomes evaluate changes in symptomatology on self-report anxiety and depression measures, as well as changes in social/community participation, social network, and perceived social support, loneliness, quality of life, and use of health services. Economic benefits will be evaluated using a cost-utility analysis to derive the incremental cost utility ratios for the enhanced CBT program.DiscussionOutcomes from this study will provide support for the establishment of improved psychosocial treatment for older adults with anxiety and/or depression. Study outcomes will also provide health systems with a clear means to reduce the impact of poor emotional health in older age and its associated economic burden. In addition to the empirical validation of a novel treatment, the current study will contribute to the current understanding of the role of social participation in older adult wellbeing.Trial registrationProspectively registered on the Australian New Zealand Clinical Trials Registry (ID: ACTRN12619000242123; registered 19th February 2019) and the ISRCTN registry (ID: ISRCTN78951376; registered 10th July 2019).

Published
2022
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2. Threat appraisal and negative affect under ambiguity in generalised anxiety disorder

Author

Peter F. Lovibond and Jessamine Tsan Hsiang Chen

Subjects
Expectancy theory, 050103 clinical psychology, media_common.quotation_subject, 05 social sciences, Uncertainty, Ambiguity, Anxiety Disorders, 030227 psychiatry, Affect, 03 medical and health sciences, Psychiatry and Mental health, Clinical Psychology, 0302 clinical medicine, Generalised anxiety disorder, Group interaction, medicine, Humans, Anxiety, 0501 psychology and cognitive sciences, medicine.symptom, Psychology, media_common, Clinical psychology
Abstract

Generalised anxiety disorder (GAD) is one of the most common anxiety disorders, yet its mechanisms remain poorly understood. In the current study, we assessed threat processing and negative affect under conditions of uncertainty and ambiguity in a sample of treatment-seeking individuals with GAD (n = 34) and in community controls (n = 34). Participants completed a laboratory aversive learning task based on that used by Grupe and Nitschke (2011). A bias in threat expectancy was observed in GAD participants relative to controls for an ambiguous cue that had not been mentioned in the instructions. GAD participants also overestimated the number of times this ambiguous cue had been followed by an aversive outcome, relative to an instructed uncertain cue (50 %). This covariation bias was not observed in controls. GAD participants also reported significantly stronger negative affect towards the ambiguous cue than the uncertain cue, a pattern that was not observed in controls, although the group interaction did not reach significance. These results provide preliminary evidence that ambiguity - rather than uncertainty per se - may be a particularly powerful trigger for biased threat appraisal and negative affect in GAD.

Published
2020

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