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303 results on '"Jensen, Tina K."'

1. Prenatal Androgen Exposure and Traits of Autism Spectrum Disorder in the Offspring: Odense Child Cohort

Author

Palm, Camilla V. B., Glintborg, Dorte, Find, Laura G., Larsen, Pia V., Dalgaard, Cilia M., Boye, Henriette, Jensen, Tina K., Dreyer, Anja F., Andersen, Marianne S., and Bilenberg, Niels

Abstract

Fetal androgen exposure may be associated with autism spectrum disorder (ASD). We studied 1777 mother-child pairs in the prospective Odense Child Cohort. Prenatal androgen exposure was assessed by maternal 3rd trimester testosterone concentrations, maternal polycystic ovary syndrome (PCOS), and 3 months offspring anogenital distance. ASD traits were assessed at age 3 years with the ASD-symptom scale of the Child Behavior Checklist for ages 1 1/2-5 years. Maternal testosterone was positively associated with traits of ASD in boys (p < 0.05). Maternal PCOS was associated with increased offspring ASD traits (p = 0.046), but became non-significant after excluding parental psychiatric diagnosis. Offspring anogenital distance was not linked to ASD traits. Higher prevalence of ASD in boys could be linked to higher susceptibility to fetal androgen exposure.

Published
2023
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4. Cumulative risk assessment of five phthalates in European children and adolescents

Author

Lange, Rosa, Vogel, Nina, Schmidt, Phillipp, Gerofke, Antje, Luijten, Mirjam, Bil, Wieneke, Santonen, Tiina, Schoeters, Greet, Gilles, Liese, Sakhi, Amrit K., Haug, Line S., Jensen, Tina K., Frederiksen, Hanne, Koch, Holger M., Szigeti, Tamás, Szabados, Máté, Tratnik, Janja Snoj, Mazej, Darja, Gabriel, Catherine, Sarigiannis, Dimosthenis, Dzhedzheia, Vazha, Karakitsios, Spyros, Rambaud, Loïc, Riou, Margaux, Koppen, Gudrun, Covaci, Adrian, Zvonař, Martin, Piler, Pavel, Klánová, Jana, Fábelová, Lucia, Richterová, Denisa, Kosjek, Tina, Runkel, Agneta, Pedraza-Díaz, Susana, Verheyen, Veerle, Bastiaensen, Michiel, Esteban-López, Marta, Castaño, Argelia, and Kolossa-Gehring, Marike

Published
2022
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8. Cancer incidence in a cohort of Danish firefighters: An extended long‐term follow‐up 1968–2021.

Author

Pedersen, Julie E., Petersen, Kajsa U., Andersen, Maria‐Helena G., Saber, Anne T., Vogel, Ulla, Ebbehøj, Niels E., Jensen, Tina K., Wils, Regitze S., Bonde, Jens P., and Hansen, Johnni

Subjects
TESTICULAR cancer, BLADDER cancer, BLADDER, COLON cancer, EPIDEMIOLOGY of cancer
Abstract

Objectives: To update and extend the examination of cancer incidence in a cohort of Danish firefighters, now adding 7 years of follow‐up and 2766 additional firefighters. The primary focus was directed toward cancer sites that recently contributed to the hazard evaluation conducted by the International Agency for Research on Cancer (IARC). Methods: The updated cohort consisted of 11,827 male Danish firefighters who were followed up for cancer from 1968 to 2021. Cohort cancer morbidity was compared with a working population reference group, and standardized incidence ratios (SIR) were used for estimation of relative risks, along with 95% confidence intervals (95% CI). Results: Among full‐time firefighters, SIR of skin melanoma was 1.30 (95% CI: 1.02–1.66), and SIR = 1.37 (95% CI: 1.02–1.85) for over 5 years of employment. Slightly positive associations were also observed for cancer of the urinary bladder (SIR = 1.16; 95% CI: 0.93–1.45), prostate (SIR = 1.11; 95% CI: 0.97–1.28), and testis (SIR = 1.11; 95% CI: 0.75–1.63). Conclusions: This updated study provides evidence indicating an elevated risk of skin melanoma in firefighters. Consistent with IARC's evaluation, we also identified positive associations for urinary bladder, prostate, and testis cancer. In contrast, our findings did not suggest an increased risk of colon cancer, non‐Hodgkin lymphoma, and mesothelioma. The latter may be due to small numbers in our still relatively young cohort. Continuous follow‐up for cancer in firefighters is warranted, including assessment of influence from surveillance bias. [ABSTRACT FROM AUTHOR]

Published
2024
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16. Male Reproductive Health and Environmental Xenoestrogens

Author

Toppari, Jorma, Christiansen, Peter, Giwercman, Aleksander, Grandjean, Philippe, Guillette,, Louis J., Jégou, Bernard, Jensen, Tina K., Jouannet, Pierre, Keiding, Niels, Leffers, Henrik, McLachlan, John A., Meyer, Otto, Müller, Jørn, Meyts, Ewa Rajpert-De, Scheike, Thomas, Sharpe, Richard, Sumpter, John, and Skakkebæk, Niels E.

Published
1996
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17. Prenatal paraben exposures and birth size:Sex-specific associations in a healthy population - A study from the Odense Child Cohort

Author

Bräuner, Elvira V, Uldbjerg, Cecilie S, Beck, Astrid L, Lim, Youn-Hee, Boye, Henriette, Frederiksen, Hanne, Andersson, Anna-Maria, Jensen, Tina K, Bräuner, Elvira V, Uldbjerg, Cecilie S, Beck, Astrid L, Lim, Youn-Hee, Boye, Henriette, Frederiksen, Hanne, Andersson, Anna-Maria, and Jensen, Tina K

Abstract

OBJECTIVES: To investigate the sex-specific associations between maternal paraben concentrations in second trimester urine and birth size of the offspring.METHODS: A prospective cohort study of 529 mother-child pairs within the Odense Child Cohort. Pregnant women were recruited to the cohort from 2010 to 2012 and provided fasting spot urine samples in second trimester (median 28.7 weeks). Concentrations of methylparaben (MeP), ethylparaben (EtP), iso-propylparaben (i-PrP), n-propylparaben (n-PrP), n-butylparaben (n-BuP) and benzylparaben (BzP) were analyzed by isotope diluted liquid-chromatography tandem-mass-spectrometry and osmolality adjusted. Exposures were categorized into tertiles or above/below level of detection. Data on maternal and birth characteristics were extracted from hospital records. Sex-stratified multiple linear regression analyses were performed according to relevant birth outcomes (length, weight, head/abdominal circumference) adjusting for a priori defined confounders.RESULTS: Higher paraben levels were detected in pregnant women who were older, more obese, who smoked and were primigravidae. Generally, higher maternal paraben exposure was consistently associated with lower birth size in female but not in male offspring, but with few substantial or statistically significant. Higher maternal exposure to n-BuP during pregnancy was associated with a statistically significant lower birth size in female offspring only [birth weight: -137 g (95 % CI -256; -19), head circumference: -0.48 cm (95 % CI -0.90; -0.05), abdominal circumference: -0.65 cm (95 % CI -1.21; -0.08)]. No differences in birth size were observed for other parabens.CONCLUSION: Higher maternal exposure to n-butylparaben was associated with lower birth size in female but not male offspring.

Published
2023

18. Higher free testosterone in the third trimester was associated with lower abdominal circumference at birth in boys: Odense child cohort.

Author

Palm, Camilla V. B., Dreyer, Anja F., Boye, Henriette, Jørgensen, Jan S., Wu, Chunsen, Højsager, Frederik D., Jensen, Tina K., Glintborg, Dorte, and Andersen, Marianne S.

Subjects
LOW birth weight, TESTOSTERONE, POLYCYSTIC ovary syndrome, BIRTH weight, BODY mass index
Abstract

Objective: To investigate associations between maternal testosterone status and offspring birth anthropometrics. Design: Population‐based prospective cohort study. Setting: University Hospital. Population: 1486 mother–child dyads from Odense Child Cohort. Methods: Maternal blood samples were collected at gestational weeks 27–30 and free testosterone (FT) levels were calculated using the Vermeulen equation from total testosterone (TT) analysed by mass spectrometry and sex hormone binding globulin. Associations between FT or TT levels and birth anthropometrics were analysed with multiple linear regression models according to offspring sex with adjustment for maternal age, parity, smoking and educational level. Analyses were repeated with polycystic ovary syndrome as exposure for offspring birth anthropometrics. Main outcome measures: Offspring birth weight (BW), birth length, abdominal and head circumferences. Results: Maternal mean (SD) age was 30.2 (4.5) years and pre‐pregnancy body mass index was 23.5 (5.3) kg/m2. In boys (n = 787), higher FT was associated with lower birth weight (adjusted doubling constant = −65.53, P = 0.010), shorter birth length (adjusted doubling constant = −0.43, P < 0.001), and lower abdominal circumference (adjusted doubling constant = −0.39, P < 0.001); Higher TT was associated with lower abdominal circumference (adjusted doubling constant = −0.25, P = 0.028). In girls, no associations were found between maternal FT or TT and offspring anthropometrics. Conclusions: Higher maternal free testosterone exposure was linked to reduced birth weight, length and abdominal circumference in boys, whereas girls were not susceptible to maternal testosterone exposure. [ABSTRACT FROM AUTHOR]

Published
2024
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23. Prenatal and early childhood predictors of intelligence quotient (IQ) in 7-year-old Danish children from the Odense Child Cohort.

Author

Beck, Iben H., Bilenberg, Niels, Davidsen, Kirstine A., Rasmussen, Anne A., Boye, Henriette, and Jensen, Tina K.

Subjects
OBESITY, CONFIDENCE intervals, CHILD development, PSYCHOLOGY of mothers, TIME, REGRESSION analysis, SEX distribution, INTELLECT, QUESTIONNAIRES, DESCRIPTIVE statistics, CEPHALOMETRY, BREASTFEEDING, RESEARCH funding, INTELLIGENCE tests, EDUCATIONAL attainment, CHILDREN
Abstract

Background: Cognitive development measured as intelligence quotient can predict socioeconomic markers in adulthood. It is therefore of interest to determine predictors of childhood intelligence quotient. Aim: To assess intelligence quotient scores based on standardised Danish age-appropriate scores and to evaluate potential predictors of intelligence quotient. Materials: At 7 years of age children in the Odense Child Cohort completed an abbreviated version of the Wechsler intelligence scale for children 5th edition consisting of four subtests (vocabulary, similarities, block design and matrix reasoning) from which the full scale intelligence quotient and verbal comprehension index were estimated. Potential predictors from pregnancy through childhood were collected from questionnaires, birth records and clinical examinations. Methods: Intelligence quotient scores were investigated through descriptive statistics and linear regression models. Results: The mean full scale intelligence quotient among 1375 children was 99.1 (95% confidence interval 98.5; 99.8) points. Higher full scale intelligence quotient scores were observed in girls 100.8 (95% confidence interval 100.0; 101.8) compared to boys 97.6 (96.7; 98.4), and in children of mothers with high and intermediate education 101.7 (100.4; 103.1) and 99.6 (98.7; 100.5), respectively, compared to low education 96.1 (94.9; 97.3). In linear regression analyses, longer maternal education and child sex (girls) remained strong predictors of intelligence quotient at age 7 years. In addition, paternal education, child head circumference and longer duration of breastfeeding were associated with higher intelligence quotient, whereas maternal overweight and obesity before pregnancy was associated with lower intelligence quotient. Conclusions: Mean intelligence quotient scores were comparable to the standardised mean intelligence quotient of 100 point of Danish peers. It is important to follow up these children to determine which predictors persist into adulthood. [ABSTRACT FROM AUTHOR]

Published
2023
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28. Elevated blood pressure in pregnant women with gestational diabetes according to the WHO criteria: importance of overweight

Author

Birukov, Anna, primary, Glintborg, Dorte, additional, Schulze, Matthias B., additional, Jensen, Tina K., additional, Kuxhaus, Olga, additional, Andersen, Louise B., additional, Kräker, Kristin, additional, Polemiti, Elli, additional, Jensen, Boye L., additional, Jørgensen, Jan S., additional, Dechend, Ralf, additional, and Andersen, Marianne S., additional

Published
2022
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32. sj-docx-2-sjp-10.1177_14034948221077463 ��� Supplemental material for Prenatal and early childhood predictors of intelligence quotient (IQ) in 7-year-old Danish children from the Odense Child Cohort

Author

Beck, Iben H., Bilenberg, Niels, Davidsen, Kirstine A., Rasmussen, Anne A., Boye, Henriette, and Jensen, Tina K.

Subjects
111799 Public Health and Health Services not elsewhere classified, FOS: Health sciences
Abstract

Supplemental material, sj-docx-2-sjp-10.1177_14034948221077463 for Prenatal and early childhood predictors of intelligence quotient (IQ) in 7-year-old Danish children from the Odense Child Cohort by Iben H. Beck, Niels Bilenberg, Kirstine A. Davidsen, Anne A. Rasmussen, Henriette Boye and Tina K. Jensen in Scandinavian Journal of Public Health

Published
2022
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33. sj-docx-1-sjp-10.1177_14034948221077463 ��� Supplemental material for Prenatal and early childhood predictors of intelligence quotient (IQ) in 7-year-old Danish children from the Odense Child Cohort

Author

Beck, Iben H., Bilenberg, Niels, Davidsen, Kirstine A., Rasmussen, Anne A., Boye, Henriette, and Jensen, Tina K.

Subjects
111799 Public Health and Health Services not elsewhere classified, FOS: Health sciences
Abstract

Supplemental material, sj-docx-1-sjp-10.1177_14034948221077463 for Prenatal and early childhood predictors of intelligence quotient (IQ) in 7-year-old Danish children from the Odense Child Cohort by Iben H. Beck, Niels Bilenberg, Kirstine A. Davidsen, Anne A. Rasmussen, Henriette Boye and Tina K. Jensen in Scandinavian Journal of Public Health

Published
2022
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34. sj-docx-4-sjp-10.1177_14034948221077463 ��� Supplemental material for Prenatal and early childhood predictors of intelligence quotient (IQ) in 7-year-old Danish children from the Odense Child Cohort

Author

Beck, Iben H., Bilenberg, Niels, Davidsen, Kirstine A., Rasmussen, Anne A., Boye, Henriette, and Jensen, Tina K.

Subjects
111799 Public Health and Health Services not elsewhere classified, FOS: Health sciences
Abstract

Supplemental material, sj-docx-4-sjp-10.1177_14034948221077463 for Prenatal and early childhood predictors of intelligence quotient (IQ) in 7-year-old Danish children from the Odense Child Cohort by Iben H. Beck, Niels Bilenberg, Kirstine A. Davidsen, Anne A. Rasmussen, Henriette Boye and Tina K. Jensen in Scandinavian Journal of Public Health

Published
2022
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35. sj-docx-3-sjp-10.1177_14034948221077463 ��� Supplemental material for Prenatal and early childhood predictors of intelligence quotient (IQ) in 7-year-old Danish children from the Odense Child Cohort

Author

Beck, Iben H., Bilenberg, Niels, Davidsen, Kirstine A., Rasmussen, Anne A., Boye, Henriette, and Jensen, Tina K.

Subjects
111799 Public Health and Health Services not elsewhere classified, FOS: Health sciences
Abstract

Supplemental material, sj-docx-3-sjp-10.1177_14034948221077463 for Prenatal and early childhood predictors of intelligence quotient (IQ) in 7-year-old Danish children from the Odense Child Cohort by Iben H. Beck, Niels Bilenberg, Kirstine A. Davidsen, Anne A. Rasmussen, Henriette Boye and Tina K. Jensen in Scandinavian Journal of Public Health

Published
2022
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46. 945-P: Elevated Blood Pressure in Pregnant Women with Gestational Diabetes According to the WHO Criteria: Importance of Obesity

Author

BIRUKOV, ANNA, primary, GLINTBORG, DORTE, additional, SCHULZE, MATTHIAS B., additional, JENSEN, TINA K., additional, ANDERSEN, LOUISE B., additional, KRÄKER, KRISTIN, additional, POLEMITI, ELLI, additional, JENSEN, BOYE L., additional, JOERGENSEN, JAN S., additional, DECHEND, RALF, additional, and ANDERSEN, MARIANNE S., additional

Published
2021
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