6,276 results on '"Jensen, T."'
Search Results
2. The ASPECT hydrocephalus system: investigating clinical applicability and system utility
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Toft, N M, Pedersen, S Hornshøj, Jensen, T S R, Milan, J Birch, Riedel, C S, Agerlin, N, Birkeland, P, Hauerberg, J, Larsen, C C, Munch, T N, Holst, A Vedel, and Juhler, M
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- 2024
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3. Outcomes of patients admitted with malignant small bowel obstruction: a subgroup multicentre observational cohort analysis
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Hupfeld, N. B., Burcharth, J., Jensen, T. K., Lolle, I., Nielsen, L. B. J., Tolver, M. A., Skovsen, A. P., and Smith, H. G.
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- 2024
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4. Design of an Intake and a Thruster for an Atmosphere-Breathing Electric Propulsion System
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Romano, F., Herdrich, G., Chan, Y. -A., Crisp, N. H., Roberts, P. C. E., Holmes, B. E. A., Edmondson, S., Haigh, S., Macario-Rojas, A., Oiko, V. T. A., Smith, L. A. Sinpetru K., Becedas, J., Sulliotti-Linner, V., Bisgaard, M., Christensen, S., Hanessian, V., Jensen, T. Kauffman, Nielsen, J., Fasoulas, S., Traub, C., García-Almiñana, D., Rodríguez-Donaire, S., Sureda, M., Kataria, D., Belkouchi, B., Conte, A., Seminari, S., and Villain, R.
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Physics - Space Physics ,Physics - Plasma Physics - Abstract
Challenging space missions include those at very low altitudes, where the atmosphere is source of aerodynamic drag on the spacecraft that finally defines the missions lifetime unless way to compensate for it is provided. This environment is named Very Low Earth Orbit (VLEO) and is defined for $h<450~km$. In addition to the satellite's aerodynamic design, to extend the lifetime of such missions an efficient propulsion system is required. One solution is Atmosphere-Breathing Electric Propulsion (ABEP) that collects atmospheric particles to be used as propellant for an electric thruster. The system would minimize the requirement of limited propellant availability and can also be applied to any planetary body with atmosphere, enabling new missions at low altitude ranges for longer times. One of the objectives of the H2020 DISCOVERER project, is the development of an intake and an electrode-less plasma thruster for an ABEP system. The article describes the characteristics of intake design and the respective final deigns providing collection efficiencies up to $94\%$. On the other side, the radio frequency (RF) Helicon-based plasma thruster (IPT) developed at IRS, is hereby presented as well, while its performances are being evaluated, the thruster has been operated with single atmospheric species as propellant, and has highlighted very low input power requirement for operation at comparable mass flow rates $P\sim 60~W$., Comment: arXiv admin note: substantial text overlap with arXiv:2106.15912
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- 2022
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5. Development and analysis of novel mission scenarios based on Atmosphere-Breathing Electric Propulsion (ABEP)
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Vaidya, S., Traub, C., Romano, F., Herdrich, G., Chan, Y. -A., Fasoulas, S., Roberts, P. C. E., Crisp, N., Edmondson, S., Haigh, S., Holmes, B. A., Macario-Rojas, A., Oiko, V. T. Abrao, Smith, K., Sinpetru, L., Becedas, J., Sulliotti-Linner, V., Christensen, S., Hanessian, V., Jensen, T. K., Nielsen, J., Bisgaard, M., Garcia-Alminana, D., Rodriguez-Donaire, S., Suerda, M., Garcia-Berenguer, M., Kataria, D., Villain, R., Seminari, S., Conte, A., and Belkouchi, B.
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Physics - Space Physics ,Astrophysics - Instrumentation and Methods for Astrophysics - Abstract
Operating satellites in Very Low Earth Orbit (VLEO) benefits the already expanding New Space industry in applications including Earth Observation and beyond. However, long-term operations at such low altitudes require propulsion systems to compensate for the large aerodynamic drag forces. When using conventional propulsion systems, the amount of storable propellant limits the maximum mission lifetime. The latter can be avoided by employing Atmosphere-Breathing Electric Propulsion (ABEP) system, which collects the residual atmospheric particles and uses them as propellant for an electric thruster. Thus, the requirement of on-board propellant storage can ideally be nullified. At the Institute of Space Systems (IRS) of the University of Stuttgart, an intake, and a RF Helicon-based Plasma Thruster (IPT) for ABEP system are developed within the Horizons 2020 funded DISCOVERER project. In order to assess possible future use cases, this paper proposes and analyzes several novel ABEP based mission scenarios. Beginning with technology demonstration mission in VLEO, more complex mission scenarios are derived and discussed in detail. These include, amongst others, orbit maintenance around Mars as well as refuelling and space tug missions. The results show that the ABEP system is not only able to compensate drag for orbit maintenance but also capable of performing orbital maneuvers and collect propellant for applications such as Space Tug and Refuelling. Thus, showing a multitude of different future mission applications.
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- 2022
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6. Type XV collagen
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Manon-Jensen, T., primary, Hansen, Annika H., additional, Arvanitidis, A., additional, and Karsdal, M.A., additional
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- 2024
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7. Type XII collagen
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Sinkeviciute, D., primary, Breisnes, Helene W., additional, Bay-Jensen, A.C., additional, Karsdal, M.A., additional, Manon-Jensen, T., additional, and Mortensen, J.H., additional
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- 2024
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8. Type XIV collagen
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Gillesberg, F.S., primary, Lindholm, M., additional, Karsdal, M.A., additional, Bay-Jensen, A.C., additional, Manon-Jensen, T., additional, and Sun, S., additional
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- 2024
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9. List of contributors
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Alexdottir, Marta, primary, Arvanitidis, A., additional, Bager, Cecilie Liv, additional, Bay-Jensen, A.C., additional, Bihlet, Asger R., additional, Breisnes, Helene W., additional, Cox, Thomas R., additional, Crespo-Bravo, M., additional, Engstroem, A., additional, Genovese, Federica, additional, Gillesberg, F.S., additional, Groen, S.S., additional, Gudmann, N.S., additional, Guiliani, A.E.M, additional, Hannani, M.T., additional, Hansen, Annika H., additional, Hansen, Niels U.B., additional, He, Y., additional, Heinz, A., additional, Henriksen, Kim, additional, Holm Nielsen, S., additional, Jansen, S.M., additional, Jensen, C., additional, Jessen, H., additional, Juhl, Pernille, additional, Karsdal, M.A., additional, Kehlet, S.N., additional, Kjeld, N.G., additional, Kristensen, J.H., additional, Langholm, L.L., additional, Laursen, Clara F.G., additional, Leeming, D.J., additional, Lindholm, M., additional, Lønsmann, I., additional, Luo, Y.Y., additional, Madsen, E.A., additional, Madsen, S.F., additional, Manon-Jensen, T., additional, Miner, Jeffrey H., additional, Mortensen, J.H., additional, Møller, A.L., additional, Nielsen, M.J., additional, Nissen, Neel I., additional, Pedersen, R.S., additional, Pehrsson, M., additional, Port, H., additional, Rasmussen, Daniel G.K., additional, Reese-Petersen, A.L., additional, Ricard-Blum, Sylvie, additional, Rønnow, S.R., additional, Sand, Jannie M.B., additional, Sardar, S., additional, Siebuhr, A.S., additional, Sinkeviciute, D., additional, Sparding, N., additional, Sun, S., additional, Szlarski, P.M., additional, Thorlacius-Ussing, J., additional, Thudium, Christian S., additional, Villesen, I.F., additional, White, Eric S., additional, and Willumsen, Nicholas, additional
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- 2024
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10. Radiographic graft changes following maxillary sinus floor augmentation with autogenous bone compared with composite grafts: a one-year single-blind randomized controlled trial
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Starch-Jensen, T., Ahmad, M., Bruun, N.H., Spin-Neto, R., Hellén-Halme, K., and Becktor, J.P.
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- 2024
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11. An ultrafast digitizer for continuous measurements from microwave fusion diagnostics
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Verdier, T., Vann, R.G.L., Jacobsen, A.S., Jensen, T., Rasmussen, J., Ragona, R., and Nielsen, S.K.
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- 2024
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12. Real-world accuracy of computed tomography in patients admitted with small bowel obstruction: a multicentre prospective cohort study
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Nielsen, L. B. J., Ærenlund, M. P., Alouda, M., Azzam, M., Bjerke, T., Burcharth, J., Dibbern, C. B., Jensen, T. K., Jordhøj, J. Q., Lolle, I., Malik, T., Ngo-Stuyt, L., Nielsen, E. Ø., Olausson, M., Skovsen, A. P., Tolver, M. A., and Smith, H. G.
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- 2023
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13. Intake Design for an Atmosphere-Breathing Electric Propulsion System (ABEP)
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Romano, F., Espinosa-Orozco, J., Pfeiffer, M., Herdrich, G., Crisp, N. H., Roberts, P. C. E., Holmes, B. E. A., Edmondson, S., Haigh, S., Livadiotti, S., Macario-Rojas, A., Oiko, V. T. A., Sinpetru, L. A., Smith, K., Becedas, J., Sulliotti-Linner, V., Bisgaard, M., Christensen, S., Hanessian, V., Jensen, T. Kauffman, Nielsen, J., Chan, Y. -A., Fasoulas, S., Traub, C., García-Almiñana, D., Rodríguez-Donaire, S., Sureda, M., Kataria, D., Belkouchi, B., Conte, A., Seminari, S., and Villain, R.
- Subjects
Physics - Space Physics - Abstract
Challenging space missions include those at very low altitudes, where the atmosphere is source of aerodynamic drag on the spacecraft. To extend the lifetime of such missions, an efficient propulsion system is required. One solution is Atmosphere-Breathing Electric Propulsion (ABEP) that collects atmospheric particles to be used as propellant for an electric thruster. The system would minimize the requirement of limited propellant availability and can also be applied to any planetary body with atmosphere, enabling new missions at low altitude ranges for longer times. IRS is developing, within the H2020 DISCOVERER project, an intake and a thruster for an ABEP system. The article describes the design and simulation of the intake, optimized to feed the radio frequency (RF) Helicon-based plasma thruster developed at IRS. The article deals in particular with the design of intakes based on diffuse and specular reflecting materials, which are analysed by the PICLas DSMC-PIC tool. Orbital altitudes $h=150-250$ km and the respective species based on the NRLMSISE-00 model (O, $N_2$, $O_2$, He, Ar, H, N) are investigated for several concepts based on fully diffuse and specular scattering, including hybrid designs. The major focus has been on the intake efficiency defined as $\eta_c=\dot{N}_{out}/\dot{N}_{in}$, with $\dot{N}_{in}$ the incoming particle flux, and $\dot{N}_{out}$ the one collected by the intake. Finally, two concepts are selected and presented providing the best expected performance for the operation with the selected thruster. The first one is based on fully diffuse accommodation yielding to $\eta_c<0.46$ and the second one based un fully specular accommodation yielding to $\eta_c<0.94$. Finally, also the influence of misalignment with the flow is analysed, highlighting a strong dependence of $\eta_c$ in the diffuse-based intake while, ..., Comment: Accepted Version
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- 2021
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14. The effect of increased air velocity on respirations rate and resting behavior in gestating sows on moderately warm summer days
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Brandt, P., Bjerg, B., Pedersen, P., Jensen, T., Rong, L., and Zhang, G.
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- 2024
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15. Endo-sinus bone gain following sinus membrane elevation without graft compared with sinus floor augmentation and a composite graft: a one-year single-blind randomized controlled trial
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Starch-Jensen, T., Bruun, N.H, and Spin-Neto, R.
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- 2024
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16. Le fort I osteotomy with or without concomitant removal of upper third molars: A prospective cohort study of intraoperative findings, related complications, and level of pterygomaxillary separation after down-fracture
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Valls-Ontañón, A., Ghuloom, M., Starch-Jensen, T., Kesmez, Ö., Giralt-Hernando, M., and Hernández-Alfaro, F.
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- 2024
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17. Ejby -- A new H5/6 ordinary chondrite fall in Copenhagen, Denmark
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Haack, H., Sorensen, A. N., Bischoff, A., Patzek, M., Barrat, J. -A., Midtskogen, S., Stempels, E., Laubenstein, M., Greenwood, R., Schmitt-Kopplin, P., Busemann, H., Maden, C., Bauer, K., Morino, P., Schonbachler, M., Voss, P., and Dahl-Jensen, T.
- Subjects
Astrophysics - Earth and Planetary Astrophysics ,Astrophysics - Solar and Stellar Astrophysics - Abstract
On February 6, 2016 at 21:07:19 UT, a very bright fireball was seen over the eastern part of Denmark. The weather was cloudy over eastern Denmark, but many people saw the sky light up-even in the heavily illuminated Copenhagen. Two hundred and thirty three reports of the associated sound and light phenomena were received by the Danish fireball network. We have formed a consortium to describe the meteorite and the circumstances of the fall and the results are presented in this paper. The first fragment of the meteorite was found the day after the fall, and in the following weeks, a total of 11 fragments with a total weight of 8982 g were found. The meteorite is an unbrecciated, weakly shocked (S2), ordinary H chondrite of petrologic type 5/6 (Bouvier et al. 2017). The concentration of the cosmogenic radionuclides suggests that the preatmospheric radius was rather small ~20 cm. The cosmic ray exposure age of Ejby (83 +/- 11 Ma) is the highest of an H chondrite and the second highest age for an ordinary chondrite. Using the preatmospheric orbit of the Ejby meteoroid (Spurny et al. 2017) locations of the recovered fragments, and wind data from the date of the fall, we have modeled the dark flight (below 18 km) of the fragments. The recovery location of the largest fragment can only be explained if aerodynamic effects during the dark flight phase are included. The recovery location of all other fragments are consistent with the dark flight modeling.
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- 2021
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18. Rectus diastasis increases risk of burst abdomen in emergency midline laparotomies: a matched case–control study
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Kvist, M., Henriksen, N. A., Burcharth, J., Nielsen, Y. W., and Jensen, T. K.
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- 2023
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19. Management and short-term outcomes of patients with small bowel obstruction in Denmark: a multicentre prospective cohort study
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Olausson, M., Aerenlund, M. P., Azzam, M., Bjerke, T., Burcharth, J. F. H., Dibbern, C. B., Jensen, T. K., Jordhøj, J. Q., Lolle, I., Ngo-Stuyt, L., Nielsen, E. Ø., Nielsen, L. B. J., Skovsen, A. P., Tolver, M. A., and Smith, H. G.
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- 2023
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20. Adaptive control for hindlimb locomotion in a simulated mouse through temporal cerebellar learning
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Jensen, T. P., Tata, S., Ijspeert, A. J., and Tolu, S.
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Quantitative Biology - Neurons and Cognition ,Computer Science - Neural and Evolutionary Computing - Abstract
Human beings and other vertebrates show remarkable performance and efficiency in locomotion, but the functioning of their biological control systems for locomotion is still only partially understood. The basic patterns and timing for locomotion are provided by a central pattern generator (CPG) in the spinal cord. The cerebellum is known to play an important role in adaptive locomotion. Recent studies have given insights into the error signals responsible for driving the cerebellar adaptation in locomotion. However, the question of how the cerebellar output influences the gait remains unanswered. We hypothesize that the cerebellar correction is applied to the pattern formation part of the CPG. Here, a bio-inspired control system for adaptive locomotion of the musculoskeletal system of the mouse is presented, where a cerebellar-like module adapts the step time by using the double support interlimb asymmetry as a temporal teaching signal. The control system is tested on a simulated mouse in a split-belt treadmill setup similar to those used in experiments with real mice. The results show adaptive locomotion behavior in the interlimb parameters similar to that seen in humans and mice. The control system adaptively decreases the double support asymmetry that occurs due to environmental perturbations in the split-belt protocol., Comment: To be published in NICE '20: Proceedings of the 8th Annual Neuro-inspired Computational Elements Workshop. 8 pages, 13 figures
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- 2020
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21. The second harmonic heating system for the NORTH tokamak
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Ragona, R., Jacobsen, A.S., Jensen, T., Jessen, M., Pedersen, A.C., Gryaznevich, M., and Nielsen, S.K.
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- 2023
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22. Outcomes following osteotome-mediated sinus floor elevation with Bio-Oss Collagen or no grafting material: a one-year single-blind randomized controlled trial
- Author
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Starch-Jensen, T., Bruun, N.H., and Spin-Neto, R.
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- 2023
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23. Pelvic exenteration for vulvar cancer: Postoperative morbidity and oncologic outcome – A single center retrospective analysis
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Valstad, H., Eyjolfsdottir, B., Wang, Y., Kristensen, G.B., Skeie-Jensen, T., and Lindemann, K.
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- 2023
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24. Fatigue testing of multiaxial non-proportionally loaded T-nodes
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Kamau, J.K., primary, Larsen, M.L., additional, Arora, V., additional, Holm-Jensen, T., additional, and Jepsen, M., additional
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- 2023
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25. High rate of incisional hernia observed after mass closure of burst abdomen
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Jensen, T. K., Gögenur, I., and Tolstrup, M.-B.
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- 2022
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26. Time series of freshwater macroinvertebrate abundances and site characteristics of European streams and rivers
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Welti, E, Bowler, D, Sinclair, J, Altermatt, F, Alvarez-Cabria, M, Amatulli, G, Angeler, D, Archambaud, G, Arrate Jorrin, I, Aspin, T, Azpiroz, I, Baker, N, Banares, I, Barquin Ortiz, J, Bodin, C, Bonacina, L, Bonada, N, Bottarin, R, Canedo-Arguelles, M, Csabai, Z, Datry, T, de Eyto, E, Dohet, A, Domisch, S, Dorflinger, G, Drohan, E, Eikland, K, England, J, Eriksen, T, Evtimova, V, Feio, M, Ferreol, M, Floury, M, Forcellini, M, Forio, M, Fornaroli, R, Friberg, N, Fruget, J, Garcia Marquez, J, Georgieva, G, Goethals, P, Graca, M, House, A, Huttunen, K, Jensen, T, Johnson, R, Jones, J, Kiesel, J, Larranaga, A, Leitner, P, L'Hoste, L, Lizee, M, Lorenz, A, Maire, A, Manzanos Arnaiz, J, Mckie, B, Millan, A, Muotka, T, Murphy, J, Ozolins, D, Paavola, R, Paril, P, Penas Silva, F, Polasek, M, Rasmussen, J, Rubio, M, Sanchez Fernandez, D, Sandin, L, Schafer, R, Schmidt-Kloiber, A, Scotti, A, Shen, L, Skuja, A, Stoll, S, Straka, M, Stubbington, R, Timm, H, Tyufekchieva, V, Tziortzis, I, Uzunov, Y, van der Lee, G, Vannevel, R, Varadinova, E, Varbiro, G, Velle, G, Verdonschot, P, Verdonschot, R, Vidinova, Y, Wiberg-Larsen, P, Haase, P, Welti E. A. R., Bowler D. E., Sinclair J. S., Altermatt F., Alvarez-Cabria M., Amatulli G., Angeler D. G., Archambaud G., Arrate Jorrin I., Aspin T., Azpiroz I., Baker N. J., Banares I., Barquin Ortiz J., Bodin C. L., Bonacina L., Bonada N., Bottarin R., Canedo-Arguelles M., Csabai Z., Datry T., de Eyto E., Dohet A., Domisch S., Dorflinger G., Drohan E., Eikland K. A., England J., Eriksen T. E., Evtimova V., Feio M. J., Ferreol M., Floury M., Forcellini M., Forio M. A. E., Fornaroli R., Friberg N., Fruget J. -F., Garcia Marquez J. R., Georgieva G., Goethals P., Graca M. A. S., House A., Huttunen K. -L., Jensen T. C., Johnson R. K., Jones J. I., Kiesel J., Larranaga A., Leitner P., L'Hoste L., Lizee M. -H., Lorenz A. W., Maire A., Manzanos Arnaiz J. A., Mckie B., Millan A., Muotka T., Murphy J. F., Ozolins D., Paavola R., Paril P., Penas Silva F. J., Polasek M., Rasmussen J., Rubio M., Sanchez Fernandez D., Sandin L., Schafer R. B., Schmidt-Kloiber A., Scotti A., Shen L. Q., Skuja A., Stoll S., Straka M., Stubbington R., Timm H., Tyufekchieva V. G., Tziortzis I., Uzunov Y., van der Lee G. H., Vannevel R., Varadinova E., Varbiro G., Velle G., Verdonschot P. F. M., Verdonschot R. C. M., Vidinova Y., Wiberg-Larsen P., Haase P., Welti, E, Bowler, D, Sinclair, J, Altermatt, F, Alvarez-Cabria, M, Amatulli, G, Angeler, D, Archambaud, G, Arrate Jorrin, I, Aspin, T, Azpiroz, I, Baker, N, Banares, I, Barquin Ortiz, J, Bodin, C, Bonacina, L, Bonada, N, Bottarin, R, Canedo-Arguelles, M, Csabai, Z, Datry, T, de Eyto, E, Dohet, A, Domisch, S, Dorflinger, G, Drohan, E, Eikland, K, England, J, Eriksen, T, Evtimova, V, Feio, M, Ferreol, M, Floury, M, Forcellini, M, Forio, M, Fornaroli, R, Friberg, N, Fruget, J, Garcia Marquez, J, Georgieva, G, Goethals, P, Graca, M, House, A, Huttunen, K, Jensen, T, Johnson, R, Jones, J, Kiesel, J, Larranaga, A, Leitner, P, L'Hoste, L, Lizee, M, Lorenz, A, Maire, A, Manzanos Arnaiz, J, Mckie, B, Millan, A, Muotka, T, Murphy, J, Ozolins, D, Paavola, R, Paril, P, Penas Silva, F, Polasek, M, Rasmussen, J, Rubio, M, Sanchez Fernandez, D, Sandin, L, Schafer, R, Schmidt-Kloiber, A, Scotti, A, Shen, L, Skuja, A, Stoll, S, Straka, M, Stubbington, R, Timm, H, Tyufekchieva, V, Tziortzis, I, Uzunov, Y, van der Lee, G, Vannevel, R, Varadinova, E, Varbiro, G, Velle, G, Verdonschot, P, Verdonschot, R, Vidinova, Y, Wiberg-Larsen, P, Haase, P, Welti E. A. R., Bowler D. E., Sinclair J. S., Altermatt F., Alvarez-Cabria M., Amatulli G., Angeler D. G., Archambaud G., Arrate Jorrin I., Aspin T., Azpiroz I., Baker N. J., Banares I., Barquin Ortiz J., Bodin C. L., Bonacina L., Bonada N., Bottarin R., Canedo-Arguelles M., Csabai Z., Datry T., de Eyto E., Dohet A., Domisch S., Dorflinger G., Drohan E., Eikland K. A., England J., Eriksen T. E., Evtimova V., Feio M. J., Ferreol M., Floury M., Forcellini M., Forio M. A. E., Fornaroli R., Friberg N., Fruget J. -F., Garcia Marquez J. R., Georgieva G., Goethals P., Graca M. A. S., House A., Huttunen K. -L., Jensen T. C., Johnson R. K., Jones J. I., Kiesel J., Larranaga A., Leitner P., L'Hoste L., Lizee M. -H., Lorenz A. W., Maire A., Manzanos Arnaiz J. A., Mckie B., Millan A., Muotka T., Murphy J. F., Ozolins D., Paavola R., Paril P., Penas Silva F. J., Polasek M., Rasmussen J., Rubio M., Sanchez Fernandez D., Sandin L., Schafer R. B., Schmidt-Kloiber A., Scotti A., Shen L. Q., Skuja A., Stoll S., Straka M., Stubbington R., Timm H., Tyufekchieva V. G., Tziortzis I., Uzunov Y., van der Lee G. H., Vannevel R., Varadinova E., Varbiro G., Velle G., Verdonschot P. F. M., Verdonschot R. C. M., Vidinova Y., Wiberg-Larsen P., and Haase P.
- Abstract
Freshwater macroinvertebrates are a diverse group and play key ecological roles, including accelerating nutrient cycling, filtering water, controlling primary producers, and providing food for predators. Their differences in tolerances and short generation times manifest in rapid community responses to change. Macroinvertebrate community composition is an indicator of water quality. In Europe, efforts to improve water quality following environmental legislation, primarily starting in the 1980s, may have driven a recovery of macroinvertebrate communities. Towards understanding temporal and spatial variation of these organisms, we compiled the TREAM dataset (Time seRies of European freshwAter Macroinvertebrates), consisting of macroinvertebrate community time series from 1,816 river and stream sites (mean length of 19.2 years and 14.9 sampling years) of 22 European countries sampled between 1968 and 2020. In total, the data include >93 million sampled individuals of 2,648 taxa from 959 genera and 212 families. These data can be used to test questions ranging from identifying drivers of the population dynamics of specific taxa to assessing the success of legislative and management restoration efforts.
- Published
- 2024
27. Endo-sinus bone gain following osteotome-mediated sinus floor elevation with Bio-Oss Collagen compared with no grafting material: a one-year single-blind randomized controlled trial
- Author
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Starch-Jensen, T., Bruun, N.H., and Spin-Neto, R.
- Published
- 2023
- Full Text
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28. Mild Affective Shifts and Creativity: Effects on Idea Generation, Evaluation, and Implementation Planning
- Author
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Watts, Logan L., McIntosh, Tristan J., Gibson, Carter, Mulhearn, Tyler J., Medeiros, Kelsey E., Mecca, Jensen T., and Cohen-Charash, Yochi
- Abstract
This study investigated the impact of mild shifts in affective tone (i.e., pleasant vs. unpleasant) and arousal (i.e., high vs. low) on three creative processes. Undergraduates read short stories designed to induce affective shifts and then were asked to generate solutions to a complex business problem. Shifts in affective tone and arousal interacted to influence idea generation and implementation planning, but not idea evaluation. The strongest creative performance was exhibited by participants who experienced a stable and pleasantly toned, low-arousal (i.e., relaxed) state and by those who shifted to an unpleasantly toned, high-arousal (i.e., angry) state. In contrast, those who shifted to an unpleasantly toned, low-arousal (i.e., sad) state or a pleasantly toned, high-arousal (i.e., happy) state tended to exhibit poorer creative performance. These results demonstrate the need to revisit the popular conception that organizations should promote intense levels of pleasant affect to enhance employee creativity.
- Published
- 2020
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29. Line shape analysis of the K$\beta$ transition in muonic hydrogen
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Covita, D. S., Anagnostopoulos, D. F., Fuhrmann, H., Gorke, H., Gotta, D., Gruber, A., Hirtl, A., Ishiwatari, T., Indelicato, P., Jensen, T. S., Bigot, E. -O. Le, Markushin, V. E., Nekipelov, M., Pomerantsev, V. N., Popov, V. P., Santos, J. M. F. dos, Schmid, Ph., Simons, L. M., Theisen, M., Trassinelli, M., Veloso, J. F. C. A., and Zmeskal, J.
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Physics - Atomic Physics ,Nuclear Experiment - Abstract
The K$\beta$ transition in muonic hydrogen was measured with a high-resolution crystal spectrometer. The spectrum is shown to be sensitive to the ground-state hyperfine splitting, the corresponding triplet-to-singlet ratio, and the kinetic energy distribution in the $3p$ state. The hyperfine splitting and triplet-to-singlet ratio are found to be consistent with the values expected from theoretical and experimental investigations and, therefore, were fixed accordingly in order to reduce the uncertainties in the further reconstruction of the kinetic energy distribution. The presence of high-energetic components was established and quantified in both a phenomenological, i.e. cascade-model-free fit, and in a direct deconvolution of the Doppler broadening based on the Bayesian approach., Comment: 22 pages, 21 figures
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- 2017
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30. Staging superstructures in high-$T_c$ Sr/O co-doped La$_{2-x}$Sr$_x$CuO$_{4+y}$
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Ray, P. J., Andersen, N. H., Jensen, T. B. S., Mohottala, H. E., Niedermayer, Ch., Lefmann, K., Wells, B. O., Zimmermann, M. v., and Udby, L.
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Condensed Matter - Superconductivity - Abstract
We present high energy X-ray diffraction studies on the structural phases of an optimal high-$T_c$ superconductor La$_{2-x}$Sr$_x$CuO$_{4+y}$ tailored by co-hole-doping. This is specifically done by varying the content of two very different chemical species, Sr and O, respectively, in order to study the influence of each. A superstructure known as staging is observed in all samples, with the staging number $n$ increasing for higher Sr dopings $x$. We find that the staging phases emerge abruptly with temperature, and can be described as a second order phase transition with transition temperatures slightly depending on the Sr doping. The Sr appears to correlate the interstitial oxygen in a way that stabilises the reproducibility of the staging phase both in terms of staging period and volume fraction in a specific sample. The structural details as investigated in this letter appear to have no direct bearing on the electronic phase separation previously observed in the same samples. This provides new evidence that the electronic phase separation is determined by the overall hole concentration rather than specific Sr/O content and concommittant structural details., Comment: 8 pages, incl. 4 figures
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- 2017
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31. Education and Training Needs, Methods, and Tools
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Kotsampopoulos, P., Jensen, T. V., Babazadeh, D., Strasser, T. I., Rikos, E., Nguyen, V. H., Tran, Q. T., Bhandia, R., Guillo-Sansano, E., Heussen, K., Narayan, A., Nguyen, T. L., Burt, G. M., Hatziargyriou, N., Strasser, Thomas I., editor, de Jong, Erik C. W., editor, and Sosnina, Maria, editor
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- 2020
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32. Hardware-in-the-Loop Assessment Methods
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Nguyen, V. H., Tran, Q. T., Guillo-Sansano, E., Kotsampopoulos, P., Gavriluta, C., Lauss, G., Strasser, T. I., Jensen, T. V., Heussen, K., Gehrke, O., Besanger, Y., Nguyen, T. L., Syed, M. H., Brandl, R., Arnold, G., Strasser, Thomas I., editor, de Jong, Erik C. W., editor, and Sosnina, Maria, editor
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- 2020
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33. Test Procedure and Description for System Testing
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Heussen, K., Babazadeh, D., Degefa, M. Z., Taxt, H., Merino, J., Nguyen, V. H., Teimourzadeh Baboli, P., Moghim Khavari, A., Rikos, E., Pellegrino, L., Tran, Q. T., Jensen, T. V., Kotsampopoulos, P., Strasser, T. I., Strasser, Thomas I., editor, de Jong, Erik C. W., editor, and Sosnina, Maria, editor
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- 2020
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34. Considerations for understanding protein measurements: Identification of formation, degradation and more pathological relevant epitopes
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Karsdal, M.A., Genovese, F., Rasmussen, D.G.K., Bay-Jensen, A.C., Mortensen, J.H., Holm Nielsen, S., Willumsen, N., Jensen, C., Manon-Jensen, T., Jennings, L., Reese-Petersen, A.L., Henriksen, K., Sand, J.M., Bager, C., and Leeming, D.J.
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- 2021
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35. Proceedings of the third 'international Traveling Workshop on Interactions between Sparse models and Technology' (iTWIST'16)
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Abrol, V., Absil, O., Absil, P. -A., Anthoine, S., Antoine, P., Arildsen, T., Bertin, N., Bleichrodt, F., Bobin, J., Bol, A., Bonnefoy, A., Caltagirone, F., Cambareri, V., Chenot, C., Crnojević, V., Daňková, M., Degraux, K., Eisert, J., Fadili, J. M., Gabrié, M., Gac, N., Giacobello, D., Gonzalez, A., Gonzalez, C. A. Gomez, González, A., Gousenbourger, P. -Y., Christensen, M. Græsbøll, Gribonval, R., Guérit, S., Huang, S., Irofti, P., Jacques, L., Kamilov, U. S., Kiticć, S., Kliesch, M., Krzakala, F., Lee, J. A., Liao, W., Jensen, T. Lindstrøm, Manoel, A., Mansour, H., Mohammad-Djafari, A., Moshtaghpour, A., Ngolè, F., Pairet, B., Panić, M., Peyré, G., Pižurica, A., Rajmic, P., Roblin, M., Roth, I., Sao, A. K., Sharma, P., Starck, J. -L., Tramel, E. W., van Waterschoot, T., Vukobratovic, D., Wang, L., Wirth, B., Wunder, G., and Zhang, H.
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Computer Science - Numerical Analysis ,Computer Science - Computer Vision and Pattern Recognition ,Computer Science - Information Theory ,Computer Science - Learning ,Mathematics - Optimization and Control - Abstract
The third edition of the "international - Traveling Workshop on Interactions between Sparse models and Technology" (iTWIST) took place in Aalborg, the 4th largest city in Denmark situated beautifully in the northern part of the country, from the 24th to 26th of August 2016. The workshop venue was at the Aalborg University campus. One implicit objective of this biennial workshop is to foster collaboration between international scientific teams by disseminating ideas through both specific oral/poster presentations and free discussions. For this third edition, iTWIST'16 gathered about 50 international participants and features 8 invited talks, 12 oral presentations, and 12 posters on the following themes, all related to the theory, application and generalization of the "sparsity paradigm": Sparsity-driven data sensing and processing (e.g., optics, computer vision, genomics, biomedical, digital communication, channel estimation, astronomy); Application of sparse models in non-convex/non-linear inverse problems (e.g., phase retrieval, blind deconvolution, self calibration); Approximate probabilistic inference for sparse problems; Sparse machine learning and inference; "Blind" inverse problems and dictionary learning; Optimization for sparse modelling; Information theory, geometry and randomness; Sparsity? What's next? (Discrete-valued signals; Union of low-dimensional spaces, Cosparsity, mixed/group norm, model-based, low-complexity models, ...); Matrix/manifold sensing/processing (graph, low-rank approximation, ...); Complexity/accuracy tradeoffs in numerical methods/optimization; Electronic/optical compressive sensors (hardware)., Comment: 69 pages, 22 extended abstracts, iTWIST'16 website: http://www.itwist16.es.aau.dk
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- 2016
36. First results from the NORTH tokamak
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Nielsen, S.K., Gryaznevich, M.P., Jacobsen, A.S., Jensen, T., Jessen, M., Korsholm, S.B., Rasmussen, J., Salewski, M., Senstius, M.G., Naulin, V., Nem, R.D., Korsgaard, M.L.H., Nilsson, A.C, Dam, F., Goltermann, A., Pedersen, A.C., Sutherland, M.T., Aalto, T., Hokkanen, A., Salmi, A., and Tala, T.
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- 2021
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37. Lateral ridge augmentation in the posterior part of the mandible with an autogenous bone block graft harvested from the ascending mandibular ramus. A 10-year retrospective study
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Nielsen, H.B. and Starch-Jensen, T.
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- 2021
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38. Utilizing parametric instabilities to diagnose edge density fluctuations in TCV.
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Clod, A, Ragona, R, Senstius, M G, Jensen, T, Kumar, U, Coda, S, and Nielsen, S K
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CYCLOTRON resonance ,THERMAL electrons ,ELECTRON emission ,TOKAMAKS ,RADIOMETERS - Abstract
Two-plasmon decay instabilities (TPDIs) are a class of parametric instabilities where a gyrotron beam, polarized in X-mode, decays nonlinearly into two upper hybrid waves at approximately half frequency. Here, we present the design of a simple radiometer that was installed at Tokamak á configuration variable to diagnose TPDIs as well as a novel technique that was used to calibrate the radiometer using thermal electron cyclotron emissions. We show examples of measured radiation from TPDIs that occur when the gyrotron beam intersects blob filaments in the scrape-off layer and demonstrate that the frequency separation of the TPDI daughter waves can be used to assess the densities of the blob filaments. This technique could be utilized to diagnose density fluctuations due to both blobs, ELMs, and rotating magnetic islands. [ABSTRACT FROM AUTHOR]
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- 2024
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39. Reorientational Dynamics in Y(BH4)3·xNH3 (x = 0, 3, and 7) : The Impact of NH3 on BH4- Dynamics
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Grinderslev, J. B., Häussermann, U., Jensen, T. R., Faraone, A., Nagao, M., Karlsson, M., Udovic, T. J., Andersson, Mikael S., Grinderslev, J. B., Häussermann, U., Jensen, T. R., Faraone, A., Nagao, M., Karlsson, M., Udovic, T. J., and Andersson, Mikael S.
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The reorientational dynamics of Y(BH4)3·xNH3 (x = 0, 3, and 7) was studied using quasielastic neutron scattering (QENS) and neutron spin echo (NSE). The results showed that changing the number of NH3 ligands drastically alters the reorientational mobility of the BH4– anion. From the QENS experiments, it was determined that the BH4– anion performs 2-fold reorientations around the C2 axis in Y(BH4)3, 3-fold reorientations around the C3 axis in Y(BH4)3·3NH3, and either 2-fold reorientations around the C2 axis or 3-fold reorientations around the C3 axis in Y(BH4)3·7NH3. The relaxation time of the BH4– anion at 300 K decreases from 2 × 10–7 s for x = 0 to 1 × 10–12 s for x = 3 and to 7 × 10–13 s for x = 7. In addition to the reorientational dynamics of the BH4– anion, it was shown that the NH3 ligands exhibit 3-fold reorientations around the C3 axis in Y(BH4)3·3NH3 and Y(BH4)3·7NH3 as well as 3-fold quantum mechanical rotational tunneling around the same axis at 5 K. The new insights constitute a significant step toward understanding the relationship between the addition of ligands and the enhanced ionic conductivity observed in systems such as LiBH4·xNH3 and Mg(BH4)2·xCH3NH2.
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- 2024
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40. 10th Anniversary of Inorganics: Inorganic Materials
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Nistico', R, Idriss, H, Carlos, L, Aneggi, E, Jensen, T, Jensen, TR, Nistico', R, Idriss, H, Carlos, L, Aneggi, E, Jensen, T, and Jensen, TR
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- 2024
41. Long-term outcomes with haloperidol versus placebo in acutely admitted adult ICU patients with delirium
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Mortensen, C, Andersen-Ranberg, N, Poulsen, L, Granholm, A, Rasmussen, B, Kjær, M, Lange, T, Ebdrup, B, Collet, M, Andreasen, A, Bestle, M, Uslu, B, Pedersen, H, Nielsen, L, Hästbacka, J, Jensen, T, Damgaard, K, Sommer, T, Morgen, M, Dey, N, Citerio, G, Estrup, S, Egerod, I, Samuelson, K, Perner, A, Mathiesen, O, Mortensen, Camilla Bekker, Andersen-Ranberg, Nina Christine, Poulsen, Lone Musaeus, Granholm, Anders, Rasmussen, Bodil Steen, Kjær, Maj-Brit Nørregaard, Lange, Theis, Ebdrup, Bjørn H., Collet, Marie Oxenbøll, Andreasen, Anne Sofie, Bestle, Morten Heiberg, Uslu, Bülent, Pedersen, Helle Scharling, Nielsen, Louise Gramstrup, Hästbacka, Johanna, Jensen, Troels Bek, Damgaard, Kjeld, Sommer, Trine, Morgen, Matthew, Dey, Nilanjan, Citerio, Giuseppe, Estrup, Stine, Egerod, Ingrid, Samuelson, Karin, Perner, Anders, Mathiesen, Ole, Mortensen, C, Andersen-Ranberg, N, Poulsen, L, Granholm, A, Rasmussen, B, Kjær, M, Lange, T, Ebdrup, B, Collet, M, Andreasen, A, Bestle, M, Uslu, B, Pedersen, H, Nielsen, L, Hästbacka, J, Jensen, T, Damgaard, K, Sommer, T, Morgen, M, Dey, N, Citerio, G, Estrup, S, Egerod, I, Samuelson, K, Perner, A, Mathiesen, O, Mortensen, Camilla Bekker, Andersen-Ranberg, Nina Christine, Poulsen, Lone Musaeus, Granholm, Anders, Rasmussen, Bodil Steen, Kjær, Maj-Brit Nørregaard, Lange, Theis, Ebdrup, Bjørn H., Collet, Marie Oxenbøll, Andreasen, Anne Sofie, Bestle, Morten Heiberg, Uslu, Bülent, Pedersen, Helle Scharling, Nielsen, Louise Gramstrup, Hästbacka, Johanna, Jensen, Troels Bek, Damgaard, Kjeld, Sommer, Trine, Morgen, Matthew, Dey, Nilanjan, Citerio, Giuseppe, Estrup, Stine, Egerod, Ingrid, Samuelson, Karin, Perner, Anders, and Mathiesen, Ole
- Abstract
Purpose: We assessed long-term outcomes in acutely admitted adult patients with delirium treated in intensive care unit (ICU) with haloperidol versus placebo. Methods: We conducted pre-planned analyses of 1-year outcomes in the Agents Intervening against Delirium in the ICU (AID-ICU) trial, including mortality and health-related quality of life (HRQoL) assessed by Euroqol (EQ) 5-dimension 5-level questionnaire (EQ-5D-5L) index values and EQ visual analogue scale (EQ VAS) (deceased patients were assigned the numeric value zero). Outcomes were analysed using logistic and linear regressions with bootstrapping and G-computation, all with adjustment for the stratification variables (site and delirium motor subtype) and multiple imputations for missing HRQoL values. Results: At 1-year follow-up, we obtained vital status for 96.2% and HRQoL data for 83.3% of the 1000 randomised patients. One-year mortality was 224/501 (44.7%) in the haloperidol group versus 251/486 (51.6%) in the placebo group, with an adjusted absolute risk difference of − 6.4%-points (95% confidence interval [CI] − 12.8%-points to − 0.2%-points; P = 0.045). These results were largely consistent across the secondary analyses. For HRQoL, the adjusted mean differences were 0.04 (95% CI − 0.03 to 0.11; P = 0.091) for EQ-5D-5L-5L index values, and 3.3 (95% CI − 9.3 to 17.5; P = 0.142) for EQ VAS. Conclusions: In acutely admitted adult ICU patients with delirium, haloperidol treatment reduced mortality at 1-year follow-up, but did not statistically significantly improve HRQoL.
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- 2024
42. Time to pregnancy and life expectancy:a cohort study of 18796 pregnant couples
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Lindahl-Jacobsen, R., Petersson, M. Tavlo, Priskorn, L., Skakkebæk, N. E., Juul, A., Kristensen, D. M., Eisenberg, M. L., Jensen, T. K., Lindahl-Jacobsen, R., Petersson, M. Tavlo, Priskorn, L., Skakkebæk, N. E., Juul, A., Kristensen, D. M., Eisenberg, M. L., and Jensen, T. K.
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STUDY QUESTION Is fecundity, measured as time to pregnancy (TTP), associated with mortality in parents? SUMMARY ANSWER Prolonged TTP is associated with increased mortality in both mothers and fathers in a dose–response manner. WHAT IS KNOWN ALREADY Several studies have linked both male and female fecundity to mortality. In women, infertility has been linked to several diseases, but studies suggest that the underlying conditions, rather than infertility, increase mortality. STUDY DESIGN, SIZE, DURATION A prospective cohort study was carried out on 18 796 pregnant couples, in which the pregnant women attended prophylactic antenatal care between 1973 and 1987 at a primary and tertiary care unit. The couples were followed in Danish mortality registers from their child’s birth date until death or until 2018. The follow-up period was up to 47 years, and there was complete follow-up until death, emigration or end of study. PARTICIPANTS/MATERIALS, SETTING, METHODS At the first antenatal visit, the pregnant women were asked to report the time to the current pregnancy. Inclusion was restricted to the first pregnancy, and TTP was categorised into <12 months, ≥12 months, not planned, and not available. In sub-analyses, TTP ≥12 was further categorized into 12–35, 36–60, and >60 months. Information for parents was linked to several Danish nationwide health registries. Survival analysis was used to estimate the hazard ratios (HRs) with a 95% CI for survival and adjusted for age at the first attempt to become pregnant, year of birth, socioeconomic status, mother’s smoking during pregnancy, and mother’s BMI. MAIN RESULTS AND THE ROLE OF CHANCE Mothers and fathers with TTP >60 months survived, respectively, 3.5 (95% CI: 2.6–4.3) and 2.7 (95% CI: 1.8–3.7) years shorter than parents with a TTP <12 months. The mortality was higher for fathers (HR: 1.21, 95% CI: 1.09–1.34) and mothers (HR: 1.29, 95% CI: 1.12, STUDY QUESTION: Is fecundity, measured as time to pregnancy (TTP), associated with mortality in parents? SUMMARY ANSWER: Prolonged TTP is associated with increased mortality in both mothers and fathers in a dose–response manner. WHAT IS KNOWN ALREADY: Several studies have linked both male and female fecundity to mortality. In women, infertility has been linked to several diseases, but studies suggest that the underlying conditions, rather than infertility, increase mortality. STUDY DESIGN, SIZE, DURATION: A prospective cohort study was carried out on 18 796 pregnant couples, in which the pregnant women attended prophylactic antenatal care between 1973 and 1987 at a primary and tertiary care unit. The couples were followed in Danish mortality registers from their child’s birth date until death or until 2018. The follow-up period was up to 47 years, and there was complete follow-up until death, emigration or end of study. PARTICIPANTS/MATERIALS, SETTING, METHODS: At the first antenatal visit, the pregnant women were asked to report the time to the current pregnancy. Inclusion was restricted to the first pregnancy, and TTP was categorised into <12 months, ≥12 months, not planned, and not available. In sub-analyses, TTP ≥12 was further categorized into 12–35, 36–60, and >60 months. Information for parents was linked to several Danish nationwide health registries. Survival analysis was used to estimate the hazard ratios (HRs) with a 95% CI for survival and adjusted for age at the first attempt to become pregnant, year of birth, socioeconomic status, mother’s smoking during pregnancy, and mother’s BMI. MAIN RESULTS AND THE ROLE OF CHANCE: Mothers and fathers with TTP >60 months survived, respectively, 3.5 (95% CI: 2.6–4.3) and 2.7 (95% CI: 1.8–3.7) years shorter than parents with a TTP <12 months. The mortality was higher for fathers (HR: 1.21, 95% CI: 1.09–1.34) and mothers (HR: 1.29, 95% CI: 1.12–1.49) with TTP ≥12 months compared to parents with TTP
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- 2024
43. Epidemiology of maxillofacial trauma in the elderly: A European multicenter study
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Brucoli, M., Boffano, P., Romeo, I., Corio, C., Benech, A., Ruslin, M., Forouzanfar, T., Starch-Jensen, T., Rodríguez-Santamarta, T., de Vicente, J.C., Snäll, J., Thorén, H., Aničić, B., Konstantinovic, V.S., Pechalova, P., Pavlov, N., Daskalov, H., Doykova, I., Kelemith, K., Tamme, T., Kopchak, A., Shumynskyi, I., Corre, P., Bertin, H., Goguet, Q., Anquetil, M., Louvrier, A., Meyer, C., Dovšak, T., Vozlič, D., Birk, A., Tarle, M., and Dediol, E.
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- 2020
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44. Management of mandibular condylar fractures in patients with atrophic edentulous mandibles
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Brucoli, M., Boffano, P., Romeo, I., Corio, C., Benech, A., Ruslin, M., Forouzanfar, T., Rodríguez-Santamarta, T., de Vicente, J.C., Tarle, M., Dediol, E., Pechalova, P., Pavlov, N., Daskalov, H., Doykova, I., Kelemith, K., Tamme, T., Kopchak, A., Shumynskyi, I., Corre, P., Bertin, H., Bourry, M., Guyonvarc’h, P., Dovšak, T., Vozliè, D., Birk, A., Anièiæ, B., Konstantinovic, V.S., and Starch-Jensen, T.
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- 2020
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45. Navigating the seas of co-submission: A chat with Steven West and Torben Heick Jensen
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West, S., primary and Heick Jensen, T., additional
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- 2024
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46. Increased von Willebrand Factor Processing in COPD, Reflecting Lung Epithelium Damage, Is Associated with Emphysema, Exacerbations and Elevated Mortality Risk
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Langholm LL, Rønnow SR, Sand JMB, Leeming DJ, Tal-Singer R, Miller BE, Vestbo J, Karsdal MA, and Manon-Jensen T
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von willebrand factor processing ,copd ,emphysema ,exacerbations ,increased mortality risk. ,Diseases of the respiratory system ,RC705-779 - Abstract
Lasse L Langholm,1,2 Sarah Rank Rønnow,1,3 Jannie MB Sand,1 Diana Julie Leeming,1 Ruth Tal-Singer,4 Bruce E Miller,4 Jørgen Vestbo,5 Morten A Karsdal,1 Tina Manon-Jensen1 1Nordic Bioscience A/S, Herlev, Denmark; 2University of Copenhagen, Faculty of Health and Medical Sciences, Department of Biomedical Sciences, Copenhagen, Denmark; 3University of Southern Denmark, The Faculty of Health Science, Odense, Denmark; 4Respiratory Medical Innovation, Value Evidence & Outcomes, GSK R&D, Collegeville, PA, USA; 5Division of Infection, Immunity and Respiratory Medicine, University of Manchester, and Manchester University NHS Foundation Trust, Manchester, UKCorrespondence: Lasse L LangholmNordic Bioscience A/S, Herlev Hovedgade 205-207, Herlev 2730, DenmarkTel +45 4452 5252Fax +45 4452 5251Email lla@nordicbio.comBackground: Chronic obstructive pulmonary disease (COPD) is characterized by chronic inflammation and lung tissue deterioration. Given the high vascularity of the lung, von Willebrand factor (VWF), a central component of wound healing initiation, has previously been assessed in COPD. VWF processing, which is crucial for regulating the primary response of wound healing, has not been assessed directly. Therefore, this study aimed to characterize wound healing initiation in COPD using dynamic VWF-processing biomarkers and to evaluate how these relate to disease severity and mortality.Methods: A cross-sectional analysis of plasma samples from the ECLIPSE study collected at year 1 from moderate to very severe COPD subjects (GOLD 2– 4, n=984) was performed. We applied competitive neo-epitope ELISAs specifically targeting the formation of and ADAMTS13-processed form of VWF, VWF-N and VWF-A, respectively.Results: VWF-A and VWF-N were significantly increased (VWF-N, p=0.01; VWF-A, p=0.0001) in plasma of symptomatic (mMRC score ≥ 2) compared to asymptomatic/mild symptomatic COPD subjects. Increased VWF-N and VWF-A levels were specifically associated with emphysema (VWF-N, p< 0.0001) or prior exacerbations (VWF-A, p=0.01). When dichotomized, high levels of both biomarkers were associated with increased risk of all-cause mortality (VWF-N, HR 3.5; VWF-A, HR 2.64).Conclusion: We demonstrate that changes in VWF processing were related to different pathophysiological aspects of COPD. VWF-N relates to the chronic condition of emphysema, while VWF-A was associated with the more acute events of exacerbations. This study indicates that VWF-A and VWF-N may be relevant markers for characterization of disease phenotype and are associated with mortality in COPD.Study Identifier: NCT00292552; GSK study code SCO104960.Keywords: von Willebrand factor processing, COPD, emphysema, exacerbations, increased mortality risk
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- 2020
47. The recovery of European freshwater biodiversity has come to a halt
- Author
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Haase, P, Bowler, D, Baker, N, Bonada, N, Domisch, S, Garcia Marquez, J, Heino, J, Hering, D, Jahnig, S, Schmidt-Kloiber, A, Stubbington, R, Altermatt, F, Alvarez-Cabria, M, Amatulli, G, Angeler, D, Archambaud-Suard, G, Jorrin, I, Aspin, T, Azpiroz, I, Banares, I, Ortiz, J, Bodin, C, Bonacina, L, Bottarin, R, Canedo-Arguelles, M, Csabai, Z, Datry, T, de Eyto, E, Dohet, A, Dorflinger, G, Drohan, E, Eikland, K, England, J, Eriksen, T, Evtimova, V, Feio, M, Ferreol, M, Floury, M, Forcellini, M, Forio, M, Fornaroli, R, Friberg, N, Fruget, J, Georgieva, G, Goethals, P, Graca, M, Graf, W, House, A, Huttunen, K, Jensen, T, Johnson, R, Jones, J, Kiesel, J, Kuglerova, L, Larranaga, A, Leitner, P, L'Hoste, L, Lizee, M, Lorenz, A, Maire, A, Arnaiz, J, Mckie, B, Millan, A, Monteith, D, Muotka, T, Murphy, J, Ozolins, D, Paavola, R, Paril, P, Penas, F, Pilotto, F, Polasek, M, Rasmussen, J, Rubio, M, Sanchez-Fernandez, D, Sandin, L, Schafer, R, Scotti, A, Shen, L, Skuja, A, Stoll, S, Straka, M, Timm, H, Tyufekchieva, V, Tziortzis, I, Uzunov, Y, van der Lee, G, Vannevel, R, Varadinova, E, Varbiro, G, Velle, G, Verdonschot, P, Verdonschot, R, Vidinova, Y, Wiberg-Larsen, P, Welti, E, Haase P., Bowler D. E., Baker N. J., Bonada N., Domisch S., Garcia Marquez J. R., Heino J., Hering D., Jahnig S. C., Schmidt-Kloiber A., Stubbington R., Altermatt F., Alvarez-Cabria M., Amatulli G., Angeler D. G., Archambaud-Suard G., Jorrin I. A., Aspin T., Azpiroz I., Banares I., Ortiz J. B., Bodin C. L., Bonacina L., Bottarin R., Canedo-Arguelles M., Csabai Z., Datry T., de Eyto E., Dohet A., Dorflinger G., Drohan E., Eikland K. A., England J., Eriksen T. E., Evtimova V., Feio M. J., Ferreol M., Floury M., Forcellini M., Forio M. A. E., Fornaroli R., Friberg N., Fruget J. -F., Georgieva G., Goethals P., Graca M. A. S., Graf W., House A., Huttunen K. -L., Jensen T. C., Johnson R. K., Jones J. I., Kiesel J., Kuglerova L., Larranaga A., Leitner P., L'Hoste L., Lizee M. -H., Lorenz A. W., Maire A., Arnaiz J. A. M., McKie B. G., Millan A., Monteith D., Muotka T., Murphy J. F., Ozolins D., Paavola R., Paril P., Penas F. J., Pilotto F., Polasek M., Rasmussen J. J., Rubio M., Sanchez-Fernandez D., Sandin L., Schafer R. B., Scotti A., Shen L. Q., Skuja A., Stoll S., Straka M., Timm H., Tyufekchieva V. G., Tziortzis I., Uzunov Y., van der Lee G. H., Vannevel R., Varadinova E., Varbiro G., Velle G., Verdonschot P. F. M., Verdonschot R. C. M., Vidinova Y., Wiberg-Larsen P., Welti E. A. R., Haase, P, Bowler, D, Baker, N, Bonada, N, Domisch, S, Garcia Marquez, J, Heino, J, Hering, D, Jahnig, S, Schmidt-Kloiber, A, Stubbington, R, Altermatt, F, Alvarez-Cabria, M, Amatulli, G, Angeler, D, Archambaud-Suard, G, Jorrin, I, Aspin, T, Azpiroz, I, Banares, I, Ortiz, J, Bodin, C, Bonacina, L, Bottarin, R, Canedo-Arguelles, M, Csabai, Z, Datry, T, de Eyto, E, Dohet, A, Dorflinger, G, Drohan, E, Eikland, K, England, J, Eriksen, T, Evtimova, V, Feio, M, Ferreol, M, Floury, M, Forcellini, M, Forio, M, Fornaroli, R, Friberg, N, Fruget, J, Georgieva, G, Goethals, P, Graca, M, Graf, W, House, A, Huttunen, K, Jensen, T, Johnson, R, Jones, J, Kiesel, J, Kuglerova, L, Larranaga, A, Leitner, P, L'Hoste, L, Lizee, M, Lorenz, A, Maire, A, Arnaiz, J, Mckie, B, Millan, A, Monteith, D, Muotka, T, Murphy, J, Ozolins, D, Paavola, R, Paril, P, Penas, F, Pilotto, F, Polasek, M, Rasmussen, J, Rubio, M, Sanchez-Fernandez, D, Sandin, L, Schafer, R, Scotti, A, Shen, L, Skuja, A, Stoll, S, Straka, M, Timm, H, Tyufekchieva, V, Tziortzis, I, Uzunov, Y, van der Lee, G, Vannevel, R, Varadinova, E, Varbiro, G, Velle, G, Verdonschot, P, Verdonschot, R, Vidinova, Y, Wiberg-Larsen, P, Welti, E, Haase P., Bowler D. E., Baker N. J., Bonada N., Domisch S., Garcia Marquez J. R., Heino J., Hering D., Jahnig S. C., Schmidt-Kloiber A., Stubbington R., Altermatt F., Alvarez-Cabria M., Amatulli G., Angeler D. G., Archambaud-Suard G., Jorrin I. A., Aspin T., Azpiroz I., Banares I., Ortiz J. B., Bodin C. L., Bonacina L., Bottarin R., Canedo-Arguelles M., Csabai Z., Datry T., de Eyto E., Dohet A., Dorflinger G., Drohan E., Eikland K. A., England J., Eriksen T. E., Evtimova V., Feio M. J., Ferreol M., Floury M., Forcellini M., Forio M. A. E., Fornaroli R., Friberg N., Fruget J. -F., Georgieva G., Goethals P., Graca M. A. S., Graf W., House A., Huttunen K. -L., Jensen T. C., Johnson R. K., Jones J. I., Kiesel J., Kuglerova L., Larranaga A., Leitner P., L'Hoste L., Lizee M. -H., Lorenz A. W., Maire A., Arnaiz J. A. M., McKie B. G., Millan A., Monteith D., Muotka T., Murphy J. F., Ozolins D., Paavola R., Paril P., Penas F. J., Pilotto F., Polasek M., Rasmussen J. J., Rubio M., Sanchez-Fernandez D., Sandin L., Schafer R. B., Scotti A., Shen L. Q., Skuja A., Stoll S., Straka M., Timm H., Tyufekchieva V. G., Tziortzis I., Uzunov Y., van der Lee G. H., Vannevel R., Varadinova E., Varbiro G., Velle G., Verdonschot P. F. M., Verdonschot R. C. M., Vidinova Y., Wiberg-Larsen P., and Welti E. A. R.
- Abstract
Owing to a long history of anthropogenic pressures, freshwater ecosystems are among the most vulnerable to biodiversity loss 1. Mitigation measures, including wastewater treatment and hydromorphological restoration, have aimed to improve environmental quality and foster the recovery of freshwater biodiversity 2. Here, using 1,816 time series of freshwater invertebrate communities collected across 22 European countries between 1968 and 2020, we quantified temporal trends in taxonomic and functional diversity and their responses to environmental pressures and gradients. We observed overall increases in taxon richness (0.73% per year), functional richness (2.4% per year) and abundance (1.17% per year). However, these increases primarily occurred before the 2010s, and have since plateaued. Freshwater communities downstream of dams, urban areas and cropland were less likely to experience recovery. Communities at sites with faster rates of warming had fewer gains in taxon richness, functional richness and abundance. Although biodiversity gains in the 1990s and 2000s probably reflect the effectiveness of water-quality improvements and restoration projects, the decelerating trajectory in the 2010s suggests that the current measures offer diminishing returns. Given new and persistent pressures on freshwater ecosystems, including emerging pollutants, climate change and the spread of invasive species, we call for additional mitigation to revive the recovery of freshwater biodiversity.
- Published
- 2023
48. Direct proof of unique magnetic and superconducting phases in superoxygenated high-Tc cuprates
- Author
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Udby, L., Larsen, J., Christensen, N. B., Boehm, M., Niedermayer, Ch., Mohottala, H. E., Jensen, T. B. S., Toft-Petersen, R., Chou, F. C., Andersen, N. H., Lefmann, K., and Wells, B. O.
- Subjects
Condensed Matter - Strongly Correlated Electrons ,Condensed Matter - Materials Science ,Condensed Matter - Superconductivity - Abstract
We present a combined magnetic neutron scattering and muon spin rotation study of the nature of the magnetic and superconducting phases in electronically phase separated La(2-x)Sr(x)CuO(4+y), x = 0.04, 065, 0.09. For all samples, we find long-range modulated magnetic order below T_N ~ T_c = 39 K. In sharp contrast wit oxygen-stoichiometric La(2-x)Sr(x)CuO(4), we find that the magnetic propagation vector as well as the ordered magnetic moment is independent of Sr content and consistent with that of the 'striped' cuprates. Our study provides direct proof that superoxygenation in La(2-x)Sr(x)CuO(4+y) allows the spin stripe ordered phase to emerge and phase separate from superconducting regions with the hallmarks of optimally doped oxygen-stoichiometric La(2-x)Sr(x)CuO(4).
- Published
- 2013
- Full Text
- View/download PDF
49. Potential diagnostic value of a type X collagen neo-epitope biomarker for knee osteoarthritis
- Author
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He, Y., Manon-Jensen, T., Arendt-Nielsen, L., Petersen, K.K., Christiansen, T., Samuels, J., Abramson, S., Karsdal, M.A., Attur, M., and Bay-Jensen, A.C.
- Published
- 2019
- Full Text
- View/download PDF
50. Short implants (≤8 mm) compared to standard length implants (>8 mm) in conjunction with maxillary sinus floor augmentation: a systematic review and meta-analysis
- Author
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Nielsen, H.B., Schou, S., Isidor, F., Christensen, A.-E., and Starch-Jensen, T.
- Published
- 2019
- Full Text
- View/download PDF
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