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274 results on '"Jensen, Jan S."'

10. Humans of AI3SD: Jan Jensen

Author

Pauli, Michelle, Jensen, Jan S., Frey, Jeremy G., Kanza, Samantha, and Niranjan, Mahesan

Subjects
AI3SD, Interview
Abstract

This interview forms part of our Humans of AI3SD Series.In this Humans of AI4SD interview he discusses evolving molecules, the surprising simplicity of machine learning, improvements in openscience and his advice for early career researchers.

Published
2022

12. Clinical Outcome After Crush Versus Culotte Stenting of Coronary Artery Bifurcation Lesions: The Nordic Stent Technique Study 36-Month Follow-Up Results

Author

Kervinen, Kari, Niemelä, Matti, Romppanen, Hannu, Erglis, Andrejs, Kumsars, Indulis, Maeng, Michael, Holm, Niels R., Lassen, Jens F., Gunnes, Pål, Stavnes, Sindre, Jensen, Jan S., Galløe, Anders, Narbute, Inga, Sondore, Dace, Christiansen, Evald H., Ravkilde, Jan, Steigen, Terje K., Mannsverk, Jan, Thayssen, Per, Hansen, Knud Nørregaard, Helqvist, Steffen, Vikman, Saila, Wiseth, Rune, Aarøe, Jens, Jokelainen, Jari, and Thuesen, Leif

Published
2013
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14. Long-Term Results After Simple Versus Complex Stenting of Coronary Artery Bifurcation Lesions: Nordic Bifurcation Study 5-Year Follow-Up Results

Author

Maeng, Michael, Holm, Niels R., Erglis, Andrejs, Kumsars, Indulis, Niemelä, Matti, Kervinen, Kari, Jensen, Jan S., Galløe, Anders, Steigen, Terje K., Wiseth, Rune, Narbute, Inga, Gunnes, Pål, Mannsverk, Jan, Meyerdierks, Oliver, Rotevatn, Svein, Nikus, Kjell, Vikman, Saila, Ravkilde, Jan, James, Stefan, Aarøe, Jens, Ylitalo, Antti, Helqvist, Steffen, Sjögren, Iwar, Thayssen, Per, Virtanen, Kari, Puhakka, Mikko, Airaksinen, Juhani, Christiansen, Evald H., Lassen, Jens F., and Thuesen, Leif

Published
2013
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25. Comparison of Paclitaxel- and Sirolimus eluting stents in everyday clinical practice: the sort out II randomized trial

Author

Galloe, Anders M., Kelbaek, Henning, Thuesen, Leif, Thayssen, Per, Rasmussen, Klaus, Hansen, Peter R., Bligaard, Niels, Saunamaki, Kari, Junker, Anders, Aaroe, Jens, Abilgaard, Ulrik, Ravkilde, Jan, Engstrom, Thomas, Jensen, Jan S., Andersen, Henning R., Botker, Hans E., Galatius, Soren, Kristensen, Steen D., Madsen, Jan K., Krusell, Lars R., Abildstrom, Steen Z., Stephansen, Ghita B., and Lassen, Jens F.

Subjects
Cardiac patients -- Care and treatment, Cardiovascular instruments, Implanted -- Research, Cardiovascular instruments, Implanted -- Comparative analysis, Paclitaxel -- Research, Paclitaxel -- Comparative analysis
Abstract

Clinical trial comparing Paclitaxel- and Sirolimus eluting stents is conducted. Findings reveal that the stents used for cardiac ailments do not differ significantly.

Published
2008

33. 10-year clinical outcome of patients treated with a drug-eluting stent in the proximal left anterior descending artery segment compared with patients stented in other non-left main coronary segments

Author

Kjøller-Hansen, Lars, Bligaard, Niels, Kelbæk, Henning, Christiansen, Evald Høj, Thuesen, Leif, Hansen, Peter R, Engstrøm, Thomas, Junker, Anders, Abildgaard, Ulrik, Lassen, Jens Flensted, Jensen, Jan S, Jeppesen, Jørgen L, and Galløe, Anders M

Subjects
cardiovascular system, cardiovascular diseases
Abstract

AIMS: To determine whether patients treated with drug-eluting stents in the proximal left anterior descending artery (LAD) carried a different long-term prognosis than patients treated in other coronary artery segments.METHODS AND RESULTS: 10-year clinical outcome expressed as all-cause mortality and major adverse cardiac events (MACE: cardiac death, acute myocardial infarction, or target vessel revascularization) was determined for 1,479 patients with a single non-left main coronary stenosis treated with a first-generation drug-eluting stent in the SORT OUT II trial. The outcome of patients treated with stents in the proximal LAD (n=365) was compared with that of patients treated in a non-proximal LAD segment (n=1,114). Follow-up was 99.3% complete. All-cause mortality was 24.9% in the proximal LAD group vs. 26.3% in the non-proximal LAD group (p=0.60). MACE occurred less frequently in the proximal LAD group 24.6% vs. 31.0% with hazard ratio 0.77 (95% confidence interval: 0.61-0.97, p=0.024). After multivariate analysis that included baseline characteristics that were unevenly distributed between the groups, the hazard ratio for MACE was 0.82 (95% confidence interval: 0.65-1.03, p=0.09).CONCLUSIONS: Patients treated with a drug-eluting stent in the proximal LAD have similar, if not better, long-term clinical outcome compared with patients stented in other coronary artery segments.

Published
2018

36. Myocardial area at risk and salvage measured by T2-weighted cardiovascular magnetic resonance: Reproducibility and comparison of two T2-weighted protocols

Author

Thomsen Carsten, Mathiasen Anders B, Vejlstrup Niels, Lønborg Jacob, Jensen Jan S, and Engstrøm Thomas

Subjects
Cardiovascular magnetic resonance, area at risk, T2-weighted imaging, ST-segment elevation myocardial infarction, reproducibility, Diseases of the circulatory (Cardiovascular) system, RC666-701
Abstract

Abstract Background Late Gadolinium Enhancement (LGE) and T2-weighted cardiovascular magnetic resonance (CMR) provides a means to measure myocardial area at risk (AAR) and salvage. Several T2-weighted CMR sequences are in use, but there is no consensus in terms of which sequence to be the preferred. Therefore, the aim of the present study was to: (1) Assess the reproducibility and (2) compare the two most frequently used T2-weighted CMR protocols for measuring AAR and salvage. Methods 91 patients with ST-elevation myocardial infarction treated with primary percutaneous coronary intervention underwent a CMR scan 1-7 days after initial treatment. Two different T2-weighted protocols, varying in slice thickness and echo time (TE), were applied covering the entire left ventricle (LV) (protocol 1: TE 65 msec and slice thickness 15 mm; protocol 2: TE 100 msec and slice thickness of 8 mm). On a second scan performed 3 months later, infarct size was assessed with a standard LGE sequence. The two protocols were compared in terms of AAR and salvage index. Furthermore, intra- and interobserver reproducibility were assessed. Results Protocol 1 measures a larger AAR and salvage index than protocol 2 with a mean difference in AAR of 1 ± 8%LV (p < 0.01) and 6 ± 12 g (p < 0.01) and salvage index of 0.04 ± 0.12 (p < 0.01). Both protocols had a high intra- and interobserver reproducibility with acceptable limits of agreement (6-8%LV and 6-12 g in AAR and 0.06-0.08 in salvage index). Conclusions We report acceptable reproducibility for AAR and salvage index measured by T2-weighted images. Thus CMR is a reliable tool for measuring AAR and salvage index. Protocol 2 (8 mm slice thickness and 100 msec TE) measures slightly smaller AAR than protocol 1 (15 mm slice thickness and 65 msec TE), but the present study does not allow for a clear recommendation of either of the protocols.

Published
2011
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38. Value of Myocardial Perfusion Assessment With Coronary Computed Tomography Angiography in Patients With Recent Acute-Onset Chest Pain

Author

Sørgaard, Mathias H., primary, Linde, Jesper J., additional, Kühl, J. Tobias, additional, Kelbæk, Henning, additional, Hove, Jens D., additional, Fornitz, Gitte G., additional, Jørgensen, Tem B.S., additional, Heitmann, Merete, additional, Kragelund, Charlotte, additional, Hansen, Thomas F., additional, Abdulla, Jawdat, additional, Engstrøm, Thomas, additional, Jensen, Jan S., additional, Wiegandt, Yaffah T., additional, Høfsten, Dan E., additional, Køber, Lars V., additional, and Kofoed, Klaus F., additional

Published
2018
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40. Ten-year clinical outcome of patients treated with a drug-eluting stent in the proximal left anterior descending artery segment compared with patients stented in other non-left main coronary segments

Author

Kjøller-Hansen, Lars, primary, Bligaard, Niels, additional, Kelbæk, Henning, additional, Christiansen, Evald Høj, additional, Thuesen, Leif, additional, Hansen, Peter R., additional, Engstrøm, Thomas, additional, Junker, Anders, additional, Abildgaard, Ulrik, additional, Lassen, Jens Flensted, additional, Jensen, Jan S., additional, Jeppesen, Jørgen L., additional, and Galløe, Anders M., additional

Published
2018
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44. Randomized Comparison of Final Kissing Balloon Dilatation Versus No Final Kissing Balloon Dilatation in Patients With Coronary Bifurcation Lesions Treated With Main Vessel Stenting. Five Year Clinical Outcome in The Nordic-Baltic Bifurcation Study III

Author

Niemelä, Matti, Holm, Niels R, Kervinen, Kari, Erglis, Andrejs, Maeng, Michael, Kumsars, Indulis, Jegere, Sanda, Steigen, Terje K, Eskola, Markku, Mäkikallio, Timo, Aaberge, Lars, Jensen, Lisette Okkels, Airaksinen, Juhani, Pietilä, Mikko, Frobert, Ole, Ravkilde, Jan, Jensen, Svend Eggert, Jensen, Jan S, Helqvist, Steffen, James, Stefan, Miettinen, Heikki, Lassen, Jens F, Thuesen, Leif, and Christiansen, Evald H

Abstract

Background- It is unknown whether the preferred 1-stent bifurcation stenting approach with stenting of the main vessel (MV) and optional side branch stenting using drug-eluting stents should be finalized by a kissing balloon dilatation (FKBD). Therefore, we compared strategies of MV stenting with and without FKBD. Methods and Results- We randomized 477 patients with a bifurcation lesion to FKBD (n=238) or no FKBD (n=239) after MV stenting. The primary end point was major adverse cardiac events: cardiac death, non-procedure-related index lesion myocardial infarction, target lesion revascularization, or stent thrombosis within 6 months. The 6-month major adverse cardiac event rates were 2.1% and 2.5% (P=1.00) in the FKBD and no-FKBD groups, respectively. Procedure and fluoroscopy times were longer and more contrast media was needed in the FKBD group than in the no-FKBD group. Three hundred twenty-six patients had a quantitative coronary assessment. At 8 months, the rate of binary (re)stenosis in the entire bifurcation lesion (MV and side branch) was 11.0% versus 17.3% (P=0.11), in the MV was 3.1% versus 2.5% (P=0.68), and in the side branch was 7.9% versus 15.4% (P=0.039) in the FKBD versus no-FKBD groups, respectively. In patients with true bifurcation lesions, the side branch restenosis rate was 7.6% versus 20.0% (P=0.024) in the FKBD and no-FKBD groups, respectively. Conclusions- MV stenting strategies with and without FKBD were associated with similar clinical outcomes. FKBD reduced angiographic side branch (re)stenosis, especially in patients with true bifurcation lesions. The simple no-FKBD procedures resulted in reduced use of contrast media and shorter procedure and fluoroscopy times. Long-term data on stent thrombosis are needed. Clinical Trial Registration- URL: http://clinicaltrials.gov. Unique identifier: NCT00914199.

Published
2015

47. 10-Year Clinical Outcome After Randomization to Treatment by Sirolimus- or Paclitaxel-Eluting Coronary Stents

Author

Galløe, Anders M., primary, Kelbæk, Henning, additional, Thuesen, Leif, additional, Hansen, Henrik S., additional, Ravkilde, Jan, additional, Hansen, Peter R., additional, Christiansen, Evald H., additional, Abildgaard, Ulrik, additional, Stephansen, Ghita, additional, Lassen, Jens F., additional, Engstrøm, Thomas, additional, Jensen, Jan Skov, additional, Jeppesen, Jørgen L., additional, Bligaard, Niels, additional, Thayssen, Per, additional, Aarøe, Jens, additional, Saunamäki, Kari, additional, Junker, Anders, additional, Tilsted, Hans H., additional, Jensen, Jan S., additional, Bøtker, Hans E., additional, Galatius, Søren, additional, Larsen, Carsten T., additional, Kristensen, Steen D., additional, Krusell, Lars R., additional, Abildstrøm, Steen Z., additional, Meng, Michael, additional, Okkels, Lisette, additional, and Galløe, Anders M., additional

Published
2017
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49. Higher burden of supraventricular ectopic complexes early after catheter ablation for atrial fibrillation is associated with increased risk of recurrent atrial fibrillation

Author

Alhede, Christina, primary, Johannessen, Arne, additional, Dixen, Ulrik, additional, Jensen, Jan S, additional, Raatikainen, Pekka, additional, Hindricks, Gerhard, additional, Walfridsson, Håkan, additional, Kongstad, Ole, additional, Pehrson, Steen, additional, Englund, Anders, additional, Hartikainen, Juha, additional, Hansen, Peter S, additional, Nielsen, Jens C, additional, and Jons, Christian, additional

Published
2016
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