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2. Managing diabetes in preschool children

Author

Vandana Jain, Linda A. DiMeglio, Birgit Rami-Merhar, Frida Sundberg, Ragnar Hanas, Allison Cato, Greg Dooley, Carmel E. Smart, Jill Weissberg-Benchell, Tamara Hershey, Jeff Hitchcock, Carine de Beaufort, and Katharine D. Barnard

Subjects
Type 1 diabetes, Pediatrics, medicine.medical_specialty, business.industry, Endocrinology, Diabetes and Metabolism, 030209 endocrinology & metabolism, medicine.disease, 03 medical and health sciences, 0302 clinical medicine, Diabetes mellitus, Pediatrics, Perinatology and Child Health, Internal Medicine, medicine, 030212 general & internal medicine, business
Published
2017
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3. The Emerging Diabetes Online Community

Author

Kerri Sparling, Marisa E. Hilliard, Tamara K. Oser, Jeff Hitchcock, and Korey K. Hood

Subjects
Health Knowledge, Attitudes, Practice, Blogging, type 1 diabetes, Endocrinology, Diabetes and Metabolism, Peer support, Article, Social support, Endocrinology, Quality of life (healthcare), Cost of Illness, Diabetes management, Health care, Adaptation, Psychological, Medicine, Humans, Social media, Misinformation, patient communication, Medical education, Internet, Consumer Health Information, business.industry, Attitude to Computers, online communication, Communication, Social Support, Advocacy, Online community, 3. Good health, Self Care, Diabetes Mellitus, Type 1, Diabetes Mellitus, Type 2, type 2 diabetes, business, Social Media
Abstract

Background Diabetes self-management is complex and demanding, and isolation and burnout are common experiences. The Internet provides opportunities for people with diabetes to connect with one another to address these challenges. The aims of this paper are to introduce readers to the platforms on which Diabetes Online Community (DOC) participants interact, to discuss reasons for and risks associated with diabetes-related online activity, and to review research related to the potential impact of DOC participation on diabetes outcomes. Methods Research and online content related to diabetes online activity is reviewed, and DOC writing excerpts are used to illustrate key themes. Guidelines for meaningful participation in DOC activities for people with diabetes, families, health care providers, and industry are provided. Results Common themes around DOC participation include peer support, advocacy, self-expression, seeking and sharing diabetes information, improving approaches to diabetes data management, and humor. Potential risks include access to misinformation and threats to individuals’ privacy, though there are limited data on negative outcomes resulting from such activities. Likewise, few data are available regarding the impact of DOC involvement on glycemic outcomes, but initial research suggests a positive impact on emotional experiences, attitudes toward diabetes, and engagement in diabetes management behaviors. Conclusion The range of DOC participants, activities, and platforms is growing rapidly. The Internet provides opportunities to strengthen communication and support among individuals with diabetes, their families, health care providers, the health care industry, policy makers, and the general public. Research is needed to investigate the impact of DOC participation on self-management, quality of life, and glycemic control, and to design and evaluate strategies to maximize its positive impact.

Published
2015

4. 101 Tips for Parents of Kids with Diabetes : Wisdom for Families Living With Type 1

Author

Jeff Hitchcock and Jeff Hitchcock

Abstract

Approximately 208,000 Americans under age twenty have diagnosed diabetes, and the number is growing at an alarming rate. From 2001 to 2009, the number of American children diagnosed with type 1 diabetes rose 23 percent; for type 2 diabetes it rose 21 percent. While scientists and government organizations assess the reasons for the increase, parents are left to deal with its day-to-day ramifications, and to guide their children through the discovery and treatment process.Jeff Hitchcock, the editor of this volume, was in desperate need of advice for how to best support his young daughter after her diagnosis. When he searched for support, he was shocked by how little information existed. So he started his own support group, Children with Diabetes. And now, more than twenty years later, Children with Diabetes has answered more than twenty thousand questions from other parents, gets more than twenty thousand daily hits on its website, and has a highly respected Diabetes Team, a wealth of on-call experts for parents in need of support.In this volume, Jeff has collected a whopping 101 tips for parents. The tips answer questions such as: What does the diagnosis mean? How do I get help? Should I change my child's eating habits? What does insulin mean, and how is it used? And what should I tell my child's teacher? For ease of reference, they're categorized, so answers can quickly and easily be found. They're also provided in simple, jargon-free, and easy-to-understand language.

Published
2016

5. ISPAD Guidelines. Managing diabetes in preschool children

Author

Frida, Sundberg, Katharine, Barnard, Allison, Cato, Carine, de Beaufort, Linda A, DiMeglio, Greg, Dooley, Tamara, Hershey, Jeff, Hitchcock, Vandana, Jain, Jill, Weissberg-Benchell, Birgit, Rami-Merhar, Carmel E, Smart, and Ragnar, Hanas

Subjects
Family Health, Glycated Hemoglobin, International Agencies, Ketone Bodies, Combined Modality Therapy, Pediatrics, Hypoglycemia, Diabetes Complications, Child Development, Diabetes Mellitus, Type 1, Insulin Infusion Systems, Child, Preschool, Hyperglycemia, Quality of Life, Humans, Hypoglycemic Agents, Insulin, Healthy Lifestyle, Biomarkers, Societies, Medical
Published
2016

6. Design, synthesis and activity of a potent, selective series of N -aryl pyridinone inhibitors of p38 kinase

Author

Dean Messing, Brian S. Hickory, Alan G. Benson, Matthew J. Saabye, Jeff Hitchcock, Heather M. Madsen, Devadas Balekudru, Shaun R. Selness, Richard C. Durley, Laura D. Marrufo, Gary D. Anderson, Li Xing, Kevin D. Jerome, Michael Hepperle, Christie Lance Christopher, Rajesh V. Devraj, Elizabeth G. Webb, Thomas Owen, Ravi G. Kurumbail, Edgardo Alvira, Jeffrey L. Hirsch, Joseph B. Monahan, Paul V. Rucker, Boehm Terri L, Blevis-Bal Radhika M, Huey S. Shieh, John K. Walker, John F. Schindler, Michele A. Promo, Win Naing, and Sheri L. Bonar

Subjects
Male, Pyridones, medicine.drug_class, Stereochemistry, Clinical Biochemistry, Pharmaceutical Science, Carboxamide, p38 Mitogen-Activated Protein Kinases, Biochemistry, Chemical synthesis, Rats, Sprague-Dawley, Inhibitory Concentration 50, chemistry.chemical_compound, Drug Discovery, medicine, Animals, Humans, Enzyme Inhibitors, Molecular Biology, chemistry.chemical_classification, Molecular Structure, biology, Kinase, Aryl, Organic Chemistry, Biological activity, Rats, Enzyme Activation, Pyridazines, Disease Models, Animal, Pyrimidines, Enzyme, chemistry, Enzyme inhibitor, Drug Design, Mitogen-activated protein kinase, Microsomes, Liver, biology.protein, Molecular Medicine
Abstract

A series of N-aryl pyridinone inhibitors of p38 mitogen activated protein (MAP) kinase were designed and prepared based on the screening hit SC-25028 (1) and structural comparisons to VX-745 (5). The focus of the investigation targeted the dependence of potency and metabolic stability on the benzyloxy connectivity, the role of the C-6 position and the substitution pattern on the N-phenyl ring. Further optimization produced the highly selective and potent pyridinones 2 and 3. These inhibitors exhibited activity in both acute and chronic models of inflammation.

Published
2011
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7. Outcomes of the DAWN Youth Summits of 2007 and 2008

Author

Crystal C. Jackson, Alexandra Greene, Thomas Danne, Mark Peyrot, Anja Østergren Nielsen, Karin Lange, Kari Rosenfeld, Larry C. Deeb, Jeff Hitchcock, Francine R. Kaufman, Maartje de Wit, Barbara J. Anderson, Henk-Jan Aanstoot, Medical psychology, and EMGO - Lifestyle, overweight and diabetes

Subjects
Parents, Organizations, Schools, Adolescent, business.industry, Endocrinology, Diabetes and Metabolism, Emotions, Social Support, Congresses as Topic, World Health Organization, Diabetes Mellitus, Type 2, Patient Education as Topic, Pediatrics, Perinatology and Child Health, Diabetes Mellitus, Quality of Life, Internal Medicine, Humans, Medicine, Family, Interdisciplinary Communication, Obesity, Social science, Child, business, Societies, Medical
Published
2009
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8. Influence of the TH1/TH2 Paradigm: The Prevalence of Asthma and Allergic Diseases in Patients with Type 1 Diabetes in the United States

Author

Shih-Wen Huang and Jeff Hitchcock

Subjects
Pulmonary and Respiratory Medicine, Type 1 diabetes, Pediatrics, medicine.medical_specialty, business.industry, Disease, medicine.disease, Test (assessment), Pediatrics, Perinatology and Child Health, medicine, Immunology and Allergy, In patient, business, Asthma
Abstract

To test the TH1/TH2 paradigm, we determined the prevalence of asthma and allergic disorders (TH2-driven diseases) in children with type 1 diabetes (a TH1-driven disease) in the United States. The s...

Published
2002
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10. School Nurses Lead the Team

Author

Jeff Hitchcock

Subjects
Family Health, medicine.medical_specialty, business.industry, General Medicine, medicine.disease, Diabetes Mellitus, Type 1, Nursing, Diabetes management, Family medicine, Diabetes mellitus, Family Nursing, School Nursing, Humans, Medicine, Female, Child, business
Published
2011
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