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En 1765, 78 familles de 363 refugies acadiens furent etablies a Belle-Ile-en-Mer. L’historiographie insiste tres tot sur l’echec de cette implantation et, par la suite, de tres importantes divergences statistiques se sont opposees a une vision claire et precise du devenir de cette population acadienne. L’objectif majeur de notre travail a ete d’etablir des donnees factuelles et numeriques dument verifiees et validees et aussi exhaustives que possible. Ceci nous a permis de proposer un nouvel eclairage sur le devenir social et economique des Acadiens de Belle-Ile-en-Mer. En depit des divergences identitaires, 86,7 % des mariages furent des mariages mixtes ; 24,7 % des familles acadiennes resterent definitivement dans l’ile ; 30,1 % partirent en Louisiane et 45,2 % s’etablirent dans different ports du littoral breton.

Peripheral blood mononuclear cells (PBMC) from three adult male squirrel monkeys ( Saimiri sciureus ) were transformed by human T-cell leukemia/lymphoma virus type I (HTLV-I) by cocultivation with lethally irradiated human MT-2 cells. Three permanent monkey T-cell lines producing HTLV-I were obtained and characterized. Six weeks after inoculation seroconversion was observed in three of three monkeys inoculated with autologous transformed T cells and in two of three monkeys receiving homologous cells. Proviral DNA was detected in their PBMC at various times after inoculation, with the highest proviral load and antibody titers being found in monkeys infected with homologous cells. Monkeys inoculated with heterologous MT-2 cells did not seroconvert, and HTLV-I provirus was detected only transiently in their PBMC. To determine whether in vitro and in vivo HTLV-I infection of squirrel monkey cells led to a selection of monkey-adapted viral mutants, comparative sequencing of the proviral gp21 env between ex vivo monkey HTLV-I-infected PBMC, the inoculum, and MT-2 cells was done and no significant differences were detected. The squirrel monkey, which is naturally free of simian T-cell leukemia/lymphoma virus, thus appears to be a suitable model for evaluating HTLV-I candidate vaccines and for studying the pathogenesis of HTLV-I.

An epidemiological study was performed in French Guiana (population 115,000) to determine the prevalence and incidence of adult T-cell leukemia/lymphoma (ATL) associated with human T-cell leukemia/lymphoma virus type I (HTLV-I). From January 1990 to December 1993, all suspected cases of ATL were enrolled in this study, and their clinical, epidemiological and immunovirological features were analyzed. Out of the 19 suspected cases, 18 were considered as ATL associated with HTLV-I (8 acute forms, 8 lymphoma types and 2 smoldering cases). Before this study, only 2 ATL cases had been reported in French Guiana over a 10-year period. This demonstrates that the number of ATL cases is greatly underestimated in most tropical HTLV-I endemic areas unless a specific disease search is performed. The mean age of the patients was 41 years. While HTLV-I antibodies were present in all cases, molecular studies demonstrated a clonal integration of HTLV-I in the tumoral cells in 7 cases out of the 9 tested. Fifteen patients died within a year of diagnosis. The crude incidence rate of ATL in French Guiana is around 3.5/100,000/year, a situation similar to that found in the Caribbean and in HTLV-I-endemic regions of Japan. However it reaches around 30/100,000/year (highest incidence ever described) in a small remote ethnic group of African origin (around 6200 inhabitants). Possible causes of ATL clustering in this ethnic group are presented. © 1995 Wiley-Liss, Inc.

The aim of this study was to compare rates of human T-cell lymphotropic virus type I (HTLV-I) seroprevalence in pregnant women belonging to different ethnic groups in French Guiana and to determine the risk factors associated with HTLV-I seropositivity. All 1,873 deliveries between 1 July 1991 and 30 June 1993 in the only gynecologic and obstetric unit at Saint Laurent du Maroni were enrolled. Serologic status could be established for 1,727 women, with 75 (4.3%) being HTLV-I seropositive. The HTLV-I seroprevalence rate differed significantly between ethnic groups: 5.7% for Noir-Marron (70/1,302), 6.3% for Haitian (3/50), and 0% for Creole (126), Amerindians (166), and Hmong (64). In Noir-Marron pregnant women, HTLV-I seropositivity was associated with a maternal age of > 35 years [odds ratio (OR), 3.3; 95% confidence interval (CI), 1.4-7.6], prior miscarriage (OR, 1.7; CI, 1-2.8), prior cesarean section (OR, 2.1; CI, 1.1-4.0), a parity > 4 (OR, 4.0; CI, 1.8-8.8), a gravidity > 6 (OR, 4.2; CI, 2.0-7.2), and a negative Rhesus factor (OR, 2.2; CI, 1.1-4.5). Two separate stepwise logistic regressions were done because gravidity and parity were highly correlated. HTLV-I seropositivity remained associated with a gravidity > 6 (OR, 3.9; CI, 2.1-7.4) and a negative Rhesus factor (OR, 2.6; CI, 1.2-5.3) for the first model and with a parity > 4 (OR, 4.1; CI, 1.9-9.0) and a negative Rhesus factor (OR, 2.5; CI, 1.2-5.1) for the second model.(ABSTRACT TRUNCATED AT 250 WORDS)

Moreau J.-P. Un cas particulier d'usages agraires : les « communaux à viager ». In: Revue de géographie de Lyon, vol. 33, n°3, 1958. pp. 311-316.

Moreau Jean-Paul. La crue de la Seine en Janvier 1955, à l'amont de Paris. In: Revue du Nord, tome 37, n°147, Juillet-septembre 1955. Livraison géographique n° 4. pp. 57-64.

During the course of an outbreak of dengue type 2 on the island of Tahiti, French Polynesia, severe hemorrhagic disease was observed in an unusual number of patients shortly after the onset of a febrile illness. In at least 33 instances, these hemorrhages were severe enough to require hospitalization and 3 patients died. Gastrointestinal bleeding was the most common type of severe hemorrhage observed and gross hematuria was next most common. The available data suggested that most of the hemorrhagic episodes were etiologically related to dengue virus.

Moreau Jean-Paul. Questions agricoles en Basse-Bourgogne au XVIIIe siècle. In: Annales de Géographie, t. 59, n°317, 1950. pp. 346-353.

Voir conclusion in fine., Moreau Jean-Paul. Un aspect de l'émigration alpine : les Fribourgeois à l'étranger aux XVII et XVIIIème siècles. In: Revue de géographie de Lyon, vol. 34, n°4, 1959. pp. 315-339.

Moreau Jean-Paul. Les premiers résultats du recensement de 1961 en Italie. In: Revue du Nord, tome 44, n°175, Juillet-septembre 1962. Livraison géographique n° 11. pp. 115-122.

Moreau Jean-Paul. Le paysage rural du vignoble auxerrois aux XIXe-XXe siècles. In: Hommes et Terres du Nord, numéro hors-série 1988. Campagnes et littoraux d'Europe. Mélanges offerts à Pierre Flatrès. pp. 378-385.

Laroche R., Moreau J.-P. L'agriculture anglaise et la guerre. In: L'information geographique, volume 11, n°5, 1947. pp. 194-197.

Moreau Jean-Paul. La dépression de Joigny. In: Annales de Géographie, t. 54, n°294, 1945. pp. 93-102.

Moreau Jean-Paul. Lenteur et retard de la Revolution agricole en Basse-Bourgogne. In: Bulletin de l'Association de geographes francais, N°155-156, 20e annee, Mai-juin 1943. pp. 66-71.

La Suisse est un grand producteur d'hydroélectricité: 17,5 milliards de kWh en 1958; le coefficient par habitant est l'un des plus élevés du monde. Pourtant, l'hiver surtout, la production est loin de couvrir la consommation. Aussi la Suisse met elle en œuvre un énorme programme d'équipement, destiné à doubler la production. L'auteur décrit les réalisations en cours et les barrages projetés, puis tire les conséquences géographiques de cette grande entreprise. D'abord la transformation de la géographie de la production, de nouvelles régions] alpines (Grisons, Tessin) rattrapant ou dépassant celles qui tenaient jusqu'ici la tête (Valais, Nord des Alpes). Peut-être aussi dans l'avenir transformation de la géographie industrielle, les cantons alpins producteurs, las de voir leurs hommes et leur électricité s'enfuir vers le Plateau, désirant attirer chez eux les industries., Moreau Jean-Paul. Réalisations actuelles et grands travaux hydro-électriques en Suisse. In: Revue de géographie de Lyon, vol. 34, n°2, 1959. pp. 141-145.

De vastes pâtures communales à la fin du XVIIIe siècle sont aujourd'hui largement transformées en plantations de peupliers. Cette modification du paysage agraire s'est réalisée en 150 ans par une lente poussée d'individualisme entamant fortement tout l'ensemble d'une organisation communautaire très apparentée à celle du Nord-Est de la France., Moreau Jean-Paul. Une cause de transformation du paysage agraire en Bourgogne : la dislocation de la communauté rurale. In: Revue de géographie de Lyon, vol. 35, n°2, 1960. pp. 175-182.

Moreau Jean-Paul. Les 75 ans du tunnel du Saint-Gothard. In: Revue de géographie de Lyon, vol. 33, n°1, 1958. pp. 71-75.

Moreau Jean-Paul. Variété et harmonie du paysage français. In: Le Globe. Revue genevoise de géographie, tome 98, 1958. pp. 5-6.

Moreau J-P. Une monographie du Campidano. In: Annales de Géographie, t. 85, n°467, 1976. p. 109.