102 results on '"Jazrawi L"'
Search Results
2. The Effect of Platelet-rich Fibrin Matrix on Rotator Cuff Healing in a Rat Model
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Hasan, S., additional, Weinberg, M., additional, Khatib, O., additional, Jazrawi, L., additional, and Strauss, E., additional
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- 2015
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3. Establishing a knee preservation registry to follow patients with degenerative joint disease
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Szulc, A., primary, Murphy, H., additional, Nathasingh, C.K., additional, Lee, E., additional, Payne, A., additional, Inneh, I., additional, Wisniewski, H.-G., additional, Iorio, R., additional, Jazrawi, L., additional, Slover, J., additional, Samuels, J., additional, Strauss, E.J., additional, and Band, P.A., additional
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- 2015
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4. Surgical Simulation in Orthopaedic Skills Training
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Atesok, K., primary, Mabrey, J. D., additional, Jazrawi, L. M., additional, and Egol, K. A., additional
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- 2012
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5. The Effect of Platelet-rich Fibrin Matrix on Rotator Cuff Healing in a Rat Model.
- Author
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Hasan, S., Weinberg, M., Khatib, O., Jazrawi, L., and Strauss, E. J.
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ANIMAL experimentation ,BIOLOGICAL models ,RATS ,ROTATOR cuff injuries ,T-test (Statistics) ,WOUND healing ,STATISTICAL power analysis ,DATA analysis software ,PLATELET-rich plasma - Abstract
The purpose of the current study was to determine if the application of platelet-rich fibrin matrix could improve regeneration of the tendon-bone insertion site in a rat rotator cuff repair model. 25 Lewis syngeneic rats underwent bilateral tenotomy and repair of the supraspinatus tendon. 10 separate rats were used for PRFM harvest. All left (control) shoulders underwent transosseous rotator cuff repair, while all right (treatment) shoulders were repaired similarly with PRFM augmentation. 9 rats were sacrificed at 2-weeks and ten at 4-weeks for biomechanical testing. 3 separate rats were sacrificed at 2-weeks and 4-weeks each for histologic analysis of the insertion site. At 2 weeks, the experimental group repairs were significantly stronger in ultimate load to failure (P = 0.01), stress (P = 0.03), and stiffness (P = 0.03). Differences in biomechanical testing were not found between the groups at 4 weeks. Histological analysis revealed less collagen organization and cartilage formation at the insertion site in the experimental group. Semiquantitative histologic analysis confirmed our qualitative assessment of the specimens. PRFM does not recapitulate the native enthesis, but rather induces an exuberant and disordered healing response that is characterized by fibrovascular scar tissue. [ABSTRACT FROM AUTHOR]
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- 2016
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6. Effect of tibial positioning on the diagnosis of posterolateral rotatory instability in the posterior cruciate ligament-deficient knee * COMMENTARY
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Strauss, E. J, primary, Ishak, C., additional, Inzerillo, C., additional, Walsh, M., additional, Yildirim, G., additional, Walker, P., additional, Jazrawi, L., additional, Rosen, J., additional, and LaPrade, R. F, additional
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- 2007
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7. The use of an injectable, biodegradable calcium phosphate bone substitute for the prophylactic augmentation of osteoporotic vertebrae and the management of vertebral compression fractures.
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Bai, B, Jazrawi, L M, Kummer, F J, and Spivak, J M
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- 1999
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8. Open Surgical Management of Chronic Exertional Compartment Syndrome of the Leg
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Utkarsh Anil, Dai, A. Z., Pham, H., Werner, J., Strauss, E. J., and Jazrawi, L. M.
9. Musculoskeletal injuries in yoga
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Klifto, C. S., Bookman, J. S., Daniel Kaplan, Dold, A. P., Jazrawi, L. M., and Sapienza, A.
10. Posterior tibial slope angle in contact versus non-contact anterior cruciate ligament injuries.
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Montgomery SR Jr, Garra S, Moore M, Levitt S, Lipschultz R, Strauss E, Kaplan D, and Jazrawi L
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- Humans, Female, Male, Adult, Retrospective Studies, Risk Factors, Young Adult, Radiography, Adolescent, Anterior Cruciate Ligament Injuries surgery, Tibia diagnostic imaging, Anterior Cruciate Ligament Reconstruction methods, Propensity Score
- Abstract
Background: Increased Posterior Tibial Slope (PTS) angle has been reported to be a risk factor for primary anterior cruciate ligament (ACL) tears. However, it is unknown whether increased PTS has an associated increased risk for non-contact versus contact ACL injury., Purpose: The purpose of this study is to determine whether patients with non-contact ACL injury have a higher PTS angle than those with contact ACL injury., Methods: A total of 1700 patients who underwent primary ACL reconstruction between January 2011 and June 2023 at a single academic institution were initially included. Electronic medical records were reviewed for demographic information as well as evidence that the patient sustained a contact or non-contact ACL injury. Patients in the contact cohort were propensity score matched to patients in the non-contact cohort by age, sex and BMI. Additionally, patients in the contact cohort were then propensity score matched to a control group of patients with intact ACLs also by age, sex and BMI., Results: One hundred and two patients with contact injury were initially identified and 1598 patients with non-contact injuries were identified. Of the 102, 67 had knee X-rays that were suitable for measurement. These 67 contact injury patients were propensity score matched to 67 noncontact patient and 67 patients with intact ACLs based on age, sex and BMI. There were no significant differences between contact and non-contact cohorts in age (28.7±6.3 vs. 27.1±6.5, p = 0.147), sex (Female: 36.0% vs. 34.3%, p = 0.858), or BMI (26.7±5.6 vs 26.1±3.4, p = 0.475). There was no significant difference in PTS angle between contact versus non-contact ACL injury patients (11.6±3.0 vs.11.6±2.8, p = 0.894). There was a significant difference in PTS between the contact ACL injury and the intact cohort (11.6±3.0 vs. 10.0±3.9, p = 0.010) and the non-contact ACL injury and the intact cohort (11.6±2.8 vs. 10.0±3.9, p = 0.010)., Conclusion: There was no significant difference in the degree of PTS between patients who sustained contact versus non-contact ACL injuries. Additionally, there was a significantly increased PTS in both the contact and non-contact ACL injury cohorts compared to patients with intact ACLs., (© 2024. The Author(s), under exclusive licence to Springer-Verlag France SAS, part of Springer Nature.)
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- 2024
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11. Clinical outcomes following transtibial medial meniscal root repair are maintained at long-term follow-up.
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Moore M, Levitt S, Lin CC, Wolfe I, Alaia E, Meislin R, Strauss EJ, Jazrawi L, Alaia MJ, and Kaplan D
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- Humans, Retrospective Studies, Male, Female, Follow-Up Studies, Adult, Middle Aged, Treatment Outcome, Suture Techniques, Menisci, Tibial surgery, Menisci, Tibial diagnostic imaging, Arthroscopy methods, Tibial Meniscus Injuries surgery, Magnetic Resonance Imaging, Patient Reported Outcome Measures
- Abstract
Purpose: To evaluate long-term outcomes of patients treated with posterior medial meniscal root tear (PMMRT) repair through assessment of functional outcome scores and to identify patient surgical and magnetic resonance imaging (MRI) characteristics associated with improved outcomes., Methods: This was a single-centre, retrospective study evaluating patients who had undergone a PMMR repair using a transtibial suture pullout technique with two locking cinch sutures. This was performed as a follow-up to previously published 2-year and 5-year outcome studies, using the same cohort. All patients from the prior short-term and midterm studies were invited to participate. Patient-reported outcome (PROs) scores, including the International Knee Documentation Committee (IKDC) and Lysholm scores, were collected. Previously collected demographic data were updated based on review of the electronic medical record. Patient outcomes were assessed preoperatively, as well as at 2-year, 5-year and 8-year postoperatively. MRI outcome measurements were assessed at 2-year and 5-year follow-ups. All statistical analysis was performed using SPSS version 26., Results: Seventeen patients of the original 18 patients (94.4%) were included in the final analysis. Additionally, three patients who had additional ipsilateral surgery were excluded from the analysis of PROs. The IKDC score significantly increased from 44.7 ± 11.6 at preoperative baseline to 71.2 ± 21.3 at 8-year post-operation (p = 0.001). There were no significant differences in IKDC score between 2-year and 8-year follow-ups (p = n.s.) or 5-year and 8-year follow-ups (p = n.s.). The Lysholm score significantly increased from 49.6 ± 7.3 at preoperative baseline to 76.4 ± 17.2 at 8-year follow-up (p < 0.001). There was no significant difference in Lysholm scores between 2-year and 8-year follow-ups (p = n.s.) or 5-year and 8-year follow-ups (p = n.s.). A linear regression analysis found that 5-year IKDC scores were significantly correlated with 8-year IKDC scores (β = 0.681, p = 0.038). At 8-year follow-up, four (23.5%) patients required additional procedures on their operative knee (one total knee arthroplasty conversion)., Conclusion: Patients treated with repair of PMMRT had maintenance of clinical outcome improvements at long-term follow-up despite worsening MRI outcomes at short-term and medium-term follow-ups. While a high proportion of patients required additional procedures on their operative knee at 8-year follow-up, few of these patient's additional procedures were related to failure of their primary surgery. Providers and patients may expect durable clinical outcomes following the repair of PMMRT, irrespective of radiographic appearance., Level of Evidence: Level IV., (© 2024 European Society of Sports Traumatology, Knee Surgery and Arthroscopy.)
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- 2024
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12. Medium- to Long-term Outcomes of Fasciotomy for Chronic Exertional Compartment Syndrome: A 6-Year Mean Follow-up Study.
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Moore M, Lezak B, Berzolla E, Hughes A, Seidenberg J, Kaplan D, Strauss E, and Jazrawi L
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Background: Operative treatment of chronic exertional compartment syndrome (CECS) with fasciotomy is effective for symptomatic resolution, but outcomes at medium- to long-term follow-up are unclear., Hypothesis: Patients will have favorable satisfaction at medium- to long-term follow-up and a high return to sport (RTS) rate after fasciotomy for treatment of CECS., Study Design: Cross-sectional., Level of Evidence: Level 3., Methods: Retrospective review of patients who underwent fasciotomy for treatment of CECS from 2010 to 2021. Outcomes were assessed using Tegner Activity Scale, symptom resolution, patient satisfaction, return to activities, and EQ-5D-5L survey., Results: Fifty patients (23 male and 27 female) were included. Mean age at time of surgery was 29.0 ± 11.6 years with mean follow-up 6.0 ± 2.3 years (range, 2.6-10.9). Tegner activity scores at final follow-up were improved compared with symptom onset (mean, 5.2 vs 3.3; P < 0.01). Increased preoperative symptom duration correlated with decreased RTS (β = -0.447; P = 0.01) and return to work (RTW) (β = -0.572; P = 0.01). Patients with a previous psychiatric diagnosis (n = 15) had lower rates of RTS (β = -0.358; P = 0.03) and RTW (β = -0.471, P = 0.02). Mean time to RTS was 5.5 ± 6.1 months. Mean visual analogue scale satisfaction rate was 74.4; 36 (72.0%) patients would be willing to have their fasciotomy again. Patients with fasciotomy of 1 to 2 compartments had higher Tegner score at final follow-up ( P = 0.02) than those who had fasciotomy of >3 compartments; 19 (38.0%) patients reported experiencing paresthesia after their operation. No patients experienced major complications., Conclusion: Medium- to long-term outcomes of patients with CECS treated with fasciotomy demonstrated high satisfaction levels and high RTS rate. However, rate of minor complications including paresthesia, swelling, and cramping was high., Competing Interests: The authors report no potential conflicts in the development and publication of this article.
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- 2024
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13. The Use of Postoperative Antibiotics in Shoulder Arthroscopy Patients.
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Vasavada K, Gipsman A, Mojica E, Shankar DS, Mannino BJ, and Jazrawi L
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- Humans, Retrospective Studies, Male, Female, Middle Aged, Adult, Treatment Outcome, Incidence, Aged, Risk Factors, Arthroscopy adverse effects, Arthroscopy methods, Antibiotic Prophylaxis methods, Shoulder Joint surgery, Surgical Wound Infection prevention & control, Surgical Wound Infection epidemiology, Anti-Bacterial Agents administration & dosage, Anti-Bacterial Agents therapeutic use
- Abstract
Background: Shoulder arthroscopy and related complications like deep tissue infections have increased in the last several decades. Practice patterns have shown significant consensus among arthroscopic surgeons supporting intraoperative pre-incision antibiotic usage and against postoperative antibiotic usage. While there is consensus in practice, the absence of robust guidelines for postoperative antibiotic prophylaxis after shoulder arthroscopy warrants further research., Purpose: The purpose of this study was to determine the incidence of infection after shoulder arthroscopy in patients treated with or without postoperative prophylactic oral antibiotics., Methods: A retrospective review of shoulder arthroscopies was performed at an outpatient surgery center over a 10-year period. The primary outcome measured was infection following a procedure, initial encounter, or subsequent encounter as defined by International Classification of Disease, Tenth Revision - Clinical Modification (ICD-10 CM) codes T81.4XXA or T814XXD. Incidence of infection was calculated for both cohorts and a chi-squared test was used to determine the statistical significance of betweengroup differences in infection incidence. A priori and post hoc power analyses were performed to determine the sample size required for statistical power and statistical power of the findings given the final study sample size, respectively., Results: A total of 1,801 patients were included in the study. All patients received intraoperative pre-incision antibiotic prophylaxis. Prophylactic postoperative antibiotics were prescribed to 223 (12.38%) patients for varying durations following shoulder arthroscopy. There were zero cases of infection among patients who received antibiotics. There was one case (0.06%) of infection among the patients who did not receive antibiotics. This difference was not statistically significant (p = 0.71). Power analyses showed that the study was highly powered., Conclusions: Postoperative prophylactic oral antibiotics did not reduce the risk of infection in patients undergoing shoulder arthroscopy.
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- 2024
14. Immune Hypersensitivity Is Associated With Higher Graft Failure Rate After Osteochondral Allograft Transplantation of the Knee.
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Moore M, Vargas L, Hanidu I, Zverev S, Bi A, Triana J, Gonzalez Lomas G, Jazrawi L, Strauss E, and Campbell KA
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Purpose: To analyze the effects of 1 or more patient-reported allergies on clinical outcomes, in particular graft failure rate, and patient-reported outcomes (PROs) following osteochondral allograft transplantation (OCA) of the knee., Methods: Retrospective review of patients who underwent knee OCA from August 2010 to May 2021 with a minimum of 2-year follow-up. Patients were initially divided into 2 cohorts: those with at least 1 allergy and those without any allergies. Clinical outcomes assessed included graft failure, reoperation rates, deep vein thrombosis/pulmonary embolism, and manipulation under anesthesia/lysis of adhesions (MUA/LOA). PROs assessed, including the visual analog scale (VAS) for pain and satisfaction, the Knee injury and Osteoarthritis Outcome Score (KOOS), and return to sport rates, were compared., Results: In total, 285 patients were included with a mean clinical follow-up of 4.8 ± 2.0 years. The allergy cohort had a significantly higher rate of graft failure ( P = .008). In a regression analysis controlling for confounding variables, graft failure remained significantly associated with the presence of medication allergies (odds ratio [OR], 3.631; 95% CI, 1.139-11.577; P = .029). Furthermore, an increasing number of allergies were associated with an increased rate of graft failure (OR, 1.644; 95% CI, 1.074-2.515; P = .022). There was no difference in rate of reoperation, complications, infection, and MUA/LOA. Of the 100 patients who completed PROs, there was no difference in VAS satisfaction, pain, and any of the KOOS outcome scores or return to sport., Conclusions: The presence of 1 or more patient-reported allergies was shown to be significantly associated with OCA graft failure. Furthermore, an increasing number of patient-reported allergies were associated with a higher rate of graft failure. However, there were no significant differences in VAS satisfaction or pain, KOOS symptom, quality of life, pain, or return to sport in patients with at least 1 patient-reported allergy and those without allergies., Level of Evidence: Level III, retrospective cohort study., Competing Interests: The authors declare the following financial interests/personal relationships which may be considered as potential competing interests: L.J. reports a relationship with 10.13039/100007307Arthrex that includes Research Support; is a consultant or advisor for Mitek Systems, Smith & Nephew, and Wolters Kluwer Health; is on the editorial or governing board for the Bulletin for the Hospital for Joint Diseases and JBJS Reviews; and has stock or stock options with Lazurite. E.S. is a board member of the American Academy of Orthopaedic Surgeons, American Orthopaedic Association, Arthroscopy Association of North America, and Cartilage, Bulletin of the Hospital for Joint Diseases; has provided paid expert testimony for Arthrex, Organogenesis, Smith & Nephew, and Vericel Corporation; has equity or stocks with Better Therapeutics; has received nonfinancial support from CartiHeal Ltd; has received funding grants from 10.13039/501100009927Fidia Pharma USA, Jaypee Publishing, Stryker, Springer Media BV, and Organogenesis; and is a consultant or advisor for JRF Ortho, Subchondral Solutions, Organogenesis, Smith & Nephew, and Vericel Corporation. K.A.C. is a board member of the American Academy of Orthopaedic Surgeons and Arthroscopy Association of North America and received funding grants from 10.13039/100008894Stryker. All other authors (M.M., L.V., I.H., S.Z., A.B., J.T., G.G.L.) declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper., (© 2024 The Authors.)
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- 2024
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15. Anterior Cruciate Ligament Repair Back to the Future?
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Haskel J, Gonzalez-Lomas G, and Jazrawi L
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- Humans, Anterior Cruciate Ligament surgery, Reoperation, Suture Anchors, Anterior Cruciate Ligament Injuries surgery, Anterior Cruciate Ligament Reconstruction methods
- Abstract
Anterior cruciate ligament (ACL) repair is a procedure that has been used to treat torn ACLs dating back to the early 1900s. With unpredictable outcomes of repair, a paradigm shift led to surgeons to opt for ACL reconstruction as a new gold standard, as the evidence showed a more reliable outcome. However, there has been a recent resurgence in ACL repair worthy of review, particularly in proximal avulsions. Suture anchor repair is one repair technique in which recent studies show low failure rates, low reoperation rates, and favorable clinical outcomes. More recent data supports augmenting this strategy with suture tape. An innovation in ACL repair techniques is the Bridge-Enhanced ACL Repair (BEAR) technique, which combines a patient's whole blood with a collagen-based scaffold to augment the repair. While promising results have been shown with these techniques, narrow indications are necessary for a successful ACL repair.
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- 2023
16. A Surgeon-Volume Comparison of Opioid Prescribing Patterns to Adolescents Following Outpatient Shoulder, Hip, and Knee Arthroscopy.
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Luthringer T, Bloom DA, Manjunath A, Hutzler L, Strauss EJ, Jazrawi L, Campbell K, and Bosco JA
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- Adolescent, Arthroscopy, Humans, Outpatients, Pain, Postoperative, Practice Patterns, Physicians', Retrospective Studies, Shoulder, Analgesics, Opioid, Surgeons
- Abstract
Purpose: Given the wide variation that exists in the amount and duration of postoperative opioid medication prescribed by orthopedic surgeons, the purpose of the current study was to analyze the opioid prescribing patterns at our institution for adolescent patients undergoing outpatient sports medicine procedures Methods: A total of 468 adolescent patients (between the ages of 13 and 18 years old) who underwent outpatient shoulder, hip, or knee arthroscopy (including ACL reconstruction) between 2016 and 2018 were retrospectively identified, and demographic data were collected. Opioid prescriptions following surgery were converted to morphine milligram equivalents (MME) for direct comparison. Prescribing patterns of the 44 surgeons included in our cohort were evaluated with respect to procedures performed and overall surgical volume. High-dose prescriptions were defined as ≥ 300 MME (equivalent to 40 tabs of oxycodone/ acetaminophen [Percocet] 5/325 mg) and low-dose prescriptions were defined as < 300 MME., Results: The mean discharge prescription following outpatient arthroscopy in this patient population was 299.8 ± 271 MME. When each individual case-type was analyzed, there were significant positive correlations between surgeonvolume and MME prescribed following shoulder arthroscopy (r = 0.387, p < 0.001) and knee arthroscopy, (r = 0.350, p < 0.001). Results of logistic regression demonstrated that for every 10 additional cases performed, the odds that a given surgeon would prescribe ≥ 300 MME postoperatively increased by a factor of 1.14 (p < 0.001). There were no significant correlations observed following hip arthroscopy, anterior cruciate ligament reconstruction, or meniscus repair. Over the course of the observation period, a significant reduction in opioid prescribing was seen among the participating surgeons., Conclusion: Surgeons who perform a greater volume of outpatient shoulder and knee arthroscopy on adolescent patients were more likely to prescribe high opioid dosages postoperatively. Awareness of existing variation in narcotic prescribing patterns for patients in this age group is important for quality of care and safety improvement amidst the opioid epidemic.
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- 2022
17. Testosterone Levels Before and After Anterior Cruciate Ligament Reconstruction A Prospective Observational Study.
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Thompson K, Klein D, Sreekumar S, Kenny L, Campbell K, Alaia M, Strauss EJ, Jazrawi L, and Gonzalez-Lomas G
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- Adult, Follicle Stimulating Hormone, Humans, Male, Prospective Studies, Young Adult, Anterior Cruciate Ligament Injuries surgery, Anterior Cruciate Ligament Reconstruction, Testosterone blood
- Abstract
Purpose: Over 200,000 anterior cruciate ligament (ACL) reconstructions are performed in the US each year. The recovery process following surgery can be slow and difficult with patients suffering persistent strength and endurance deficits. Testosterone is an important anabolic hormone responsible for maintenance and development of muscle mass. While the response of the hypothalamic-pituitary axis (HPA) to surgery has been investigated, no studies exist tracking the HPA response, specifically that involved in testosterone homeostasis, to ACL reconstructions. The purpose of this study was to explore the response of endogenous testosterone production after ACL reconstruction and determine a possible correlation between perioperative testosterone levels in males and postoperative strength and clinical outcomes., Methods: This was a single-center, prospective observational study measuring preoperative and postoperative testosterone levels. Plasma testosterone, follicle stimulating hormone (FSH), and lutenizing hormone (LH) were measured before 10:30 am on the day of surgery. These were then checked at the same time of day at 1 week, 6 weeks, and 12 weeks postoperatively. Patients were also evaluated with the visual analog scale for pain (VAS), Tegner, and Lysholm scales preoperatively and at postoperative visits. Statistical analysis was performed using ANOVA and were considered significant at p < 0.05., Results: Twenty male patients with a mean age of 34.0 ± 9.2 years undergoing ACL reconstruction were enrolled between October 2017 and April 2018. Results showed a decrease in testosterone (3.7 ng/mL vs. 2.9 ng/mL, p = 0.05), free testosterone (8.2 pg/mL vs. 6.8 pg/mL, p = 0.05), and follicle stimulated hormone (1.8 mIU/mL vs. 1.7 mIU/ mL, p = 0.83) between the preoperative plasma draw and 1-week postoperative follow-up visit. Luteinizing hormone (1.1 mIU/mL vs. 1.5 mIU/mL, p = 0.11) increased postoperatively. By week 6, testosterone returned to baseline (3.7 ng/mL vs. 3.9 ng/mL), while free testosterone continued to increase through week 12. Lutenizing hormone peaked at the 1-week postoperative visit and trended downward until week 6 (1.5 mIU/mL vs. 1.4 mIU/mL, p = 0.79). Follicle stimulating hormone continued to increase after the week-1 visit through week 12. Patient reported outcomes exhibited a trend similar to hormone levels, with the lowest patient reported outcome (PRO) scores reported at week 1 and a constant trend upward. Although there were similar trends, there were no significant correlations between change in hormone levels and change in PRO scores., Conclusion: Our study emphasizes the crucial period of hormonal decrease and their return to baseline. This knowledge will contribute to the understanding and timing of hormone therapy supplementation. Short-term testosterone replacement may be beneficial to return patients to work and physical activity at a faster rate.
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- 2022
18. Primary Quadriceps Tendon Suture Anchor Repair: Case Presentation and Surgical Technique.
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Dankert JF, Mehta DD, Mahure SA, Mojica ES, Lowe DT, Leucht P, and Jazrawi L
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- Humans, Male, Middle Aged, Quadriceps Muscle surgery, Rupture surgery, Suture Techniques, Tendons, Suture Anchors, Tendon Injuries surgery
- Abstract
Summary: This case presentation described a technique for repairing an acute quadriceps tendon rupture with suture anchors. The patient was a 51-year-old man who sustained an acute quadriceps tendon rupture after a fall. We used a midline incision over the quadriceps tendon and muscle. The tendon was found to be completely avulsed from the superior border of the patella. Three suture anchors were used to re-approximate the quadriceps tendon to the patella and additional sutures were used to repair the medial and lateral patellar retinacula. The patient had excellent range of motion at his 6-week follow-up appointment after the procedure., Competing Interests: The authors report no conflict of interest., (Copyright © 2022 Wolters Kluwer Health, Inc. All rights reserved.)
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- 2022
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19. Lower extremity injuries in U.S. national fencing team members and U.S. fencing Olympians.
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Thompson K, Chang G, Alaia M, Jazrawi L, and Gonzalez-Lomas G
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- Female, Humans, Lower Extremity, Male, Hip Injuries, Knee Injuries prevention & control, Leg Injuries epidemiology, Sports
- Abstract
Introduction: Fencing is growing rapidly in popularity and competitiveness with fencers beginning at a younger age and competing in more tournaments. Even though fencing has a low risk of time-loss injury, fencers are inevitably going to experience injuries if proper athletic training and prevention does not occur. We aim to describe and compare the lower extremity injuries experienced by fencers that have trained at the highest level in the sport. We hypothesized that athletes who fenced longer would suffer more knee and hip injuries and report lower IKDC and HOS scores., Methods: This is an epidemiology study distributed to members of the U.S. national team and Olympic team from 1980 to 2018. The electronic survey included questions regarding age, weapon, number of years fencing, number of national and Olympic teams, injuries on the dominant and nondominant hip and knee, time missed due to injury, and methods for treatment. The survey also included the International Knee Demographic Committee (IKDC) and Hip Outcome Score (HOS)., Results: There were 153 national team members between July 1980 and July 2018, 110 with contact information. A total of 77 athletes submitted the survey, consisting of 30 females and 47 males. Female fencers had more hip injuries and lower IKDC and HOS scores than their male counterparts. In total, there were 71 injuries to the dominant (front) knee and 28 injuries to the nondominant (back) knee. There were 32 dominant hip injuries and 5 nondominant hip injuries. Saber fencers reported the most dominant and nondominant hip and knee injuries., Conclusion: The intense, repetitive and asymmetrical movements involved in fencing affect the weight bearing leg and the nondominant leg in all weapons. Special attention should be paid to female fencers as they experience more hip and knee injuries resulting in impaired joint function.
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- 2022
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20. Short-term complications of the Latarjet procedure: a systematic review.
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Hurley ET, Schwartz LB, Mojica ES, Campbell KA, Matache BA, Meislin RJ, and Jazrawi L
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- Arthroscopy adverse effects, Humans, Recurrence, Joint Instability, Shoulder Dislocation, Shoulder Joint
- Abstract
Purpose: The purpose of this study is to evaluate the short-term complication rate following the open and arthroscopic Latarjet procedures and to meta-analyze the studies comparing the 2 approaches., Methods: PubMed was searched according to Preferred Reporting Items for Systematic reviews and Meta-Analyses (PRISMA) guidelines to find clinical and biomechanical studies comparing complication rates in open and arthroscopic Latarjet procedures. A literature search of MEDLINE, Embase, and the Cochrane Library was performed based on the PRISMA guidelines. Clinical studies reporting on the complications following the open or arthroscopic Latarjet were included. Meta-analysis was performed for comparative studies using Review Manager, version 5.3. A P value of <.05 was considered statistically significant., Results: Overall, 89 studies (Level of Evidence [LOE] I: 2, LOE II: 2, LOE III: 24, LOE IV: 61) met inclusion criteria, with 7175 shoulders. Following the open Latarjet procedure, the overall complication rate was 6.1%, with a 1.9% occurrence of graft-related complications, 1.1% hardware, 1.1% wound, 0.9% nerve, and 1.2% other complications. Following the arthroscopic Latarjet procedure, the overall complication rate was 6.8%, with a 3.2% occurrence of graft-related complications, 1.9% hardware, 0.5% wound, 0.7% nerve, and 0.5% other complications. Complications were reported in 7 studies comparing 379 patients treated with the open Latarjet and 531 treated with the arthroscopic Latarjet, with no statistically significant difference between the two (P = .81)., Conclusion: Our study established that the overall complication rate following the Latarjet procedure was 6%-7%, with the most common complication being graft-related. Furthermore, based on the current evidence, there is no significant difference in the complication rate between the open and arthroscopic Latarjet procedures., (Copyright © 2021 Journal of Shoulder and Elbow Surgery Board of Trustees. Published by Elsevier Inc. All rights reserved.)
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- 2021
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21. Bone-Patellar Tendon-Bone Autograft Thickness Is a Risk Factor for Graft Failure. A Case-Control Analysis.
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Roach R, Anil U, Bloom DA, Pham H, Jazrawi L, Alaia MJ, and Gonzalez-Lomas G
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- Adolescent, Adult, Autografts, Case-Control Studies, Humans, Patella surgery, Reproducibility of Results, Retrospective Studies, Risk Factors, Transplantation, Autologous, Young Adult, Anterior Cruciate Ligament Injuries surgery, Anterior Cruciate Ligament Reconstruction adverse effects, Patellar Ligament diagnostic imaging, Patellar Ligament surgery
- Abstract
Background: Graft failure following anterior cruciate ligament reconstruction (ACLR) is a devastating complication. Risk factors such as patient characteristics and tunnel positions are well described. The relationship between graft dimension and failure rates has been investigated mainly in soft tissue grafts. Less studied are the effects of patella tendon (PT) dimensions on the risk of graft failure following patella tendon autograft (PTA) reconstructions., Purpose: The purpose of the current study was to investigate if patellar tendon thickness measured on preoperative magnetic resonance imaging (MRI) predicts failure after ACLR using PTA., Methods: This was an institutional review board approved, single-center, retrospective case-control study comparing patients' preoperative patellar tendon thickness between July 2005 and January 2017. Sixteen patients (mean age 21.2 ± 5.0 years) with PTA failure requiring revision surgery were identified and compared to 34 control patients who had undergone primary ACLR with PTA without failure with a minimum of 2-years follow-up. Patients with failure were matched at approximately 1:2 based on age, sex, height, weight, associated meniscus injury, and associated meniscal surgery. Patellar tendon dimensions were measured at the inferior pole of the patella (IPP), tibial tubercle insertion (TT), and longitudinal midpoint (MP) on preoperative axial and sagittal cut MRIs. Interclass correlation coefficeint (ICC) and Bland-Altman analyses were evaluated to determine inter-observer reliability. The two cohorts were compared using independent samples t-tests and analysis of variance., Results: All ACLR failures occurred after a non-contact, pivot type injury. There were no significant differences in age, sex, height, weight, meniscal injury, or meniscal surgery between the two groups. Mean time between primary ACLR and revision was 2.6 ± 2.6 years and mean follow-up time was 3.1 ± 1.0 years in the control group. Patellar tendon length and width were not significantly different between the two groups. The average thickness at both the inferior pole and longitudinal midpoint was significantly higher in the failure group compared to controls (IPP: 5.04 ± 1.1 mm versus 4.33 ± 0.7 mm, p = 0.01; MP: 4.60 ± 0.7 mm versus 4.22 ± 0.5 mm, p = 0.03). Additionally, ICC was high across all measurements, with all values > 0.978. Similarly, all values demonstrated bias of less than ± 0.05., Conclusion: Patella tendon autograft anterior cruciate ligament reconstruction failures had significantly thicker patellar tendons at the inferior pole and longitudinal midpoint of the patella tendon.
- Published
- 2021
22. Outcomes of Revision Surgery for a Failed Prior Latarjet Procedure A Systematic Review.
- Author
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Hurley E, Bloom D, Manjunath A, Jazrawi L, and Strauss E
- Subjects
- Humans, Recurrence, Shoulder Injuries complications, Treatment Outcome, Arthroplasty adverse effects, Arthroplasty methods, Joint Instability etiology, Joint Instability surgery, Reoperation methods, Shoulder Dislocation etiology
- Abstract
Purpose: This study systematically reviewed the literature for outcomes following revision surgery for a failed prior Latarjet procedure., Methods: Two independent reviewers performed the literature search based on PRISMA guidelines using the EMBASE, MEDLINE, and The Cochrane Library databases. Studies in which the Latarjet procedure was performed as a revision procedure following failed prior shoulder instability surgery were included. Clinical outcomes analyzed were: 1. functional outcomes, 2. recurrent instability, 3. range of motion, and 4., Complications: Statistical analysis was performed using IBM SPSS., Results: There were seven studies with 161 patients (162 shoulders) included. Four studies used a bone-block procedure, three used arthroscopic soft-tissue stabilization, and the mean follow-up was 49.8 months. The most commonly reported functional outcome measure was the Rowe score, with a weighted mean average of 79.7, with 82.9% of patients having good to excellent outcomes. Return to play was possible for 73.8% of patients, with 64.2% of those returning to at least the same level of competition. The overall recurrence rate was 9.5%, with 3.6% and 5.9% experiencing recurrent dislocations and subluxations, respectively. The overall revision rate was 4.2%, with all patients undergoing revisions due to recurrence. There were no reported neurovascular complications. Instability arthropathy was reported in 43.3% of patients., Conclusion: Surgical management following a failed Latarjet procedure results in moderate rates of recurrent instability and has a low intraoperative and postoperative complication rate. Additionally, the results across all techniques appear similar, with no procedure being identified as the gold-standard in the literature. However, there was a concerning rate of instability arthropathy, which may be related to the failure of a bony procedure.
- Published
- 2020
23. A Focused Gap Year Program in Orthopaedic Research: An 18-Year Experience.
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Egol KA, Shields CN, Errico T, Iorio R, Jazrawi L, Strauss E, Rokito A, and Zuckerman JD
- Subjects
- Cohort Studies, Humans, Internship and Residency, Mentors, Surveys and Questionnaires, Time Factors, Education, Medical methods, Education, Medical statistics & numerical data, Orthopedic Procedures education, Orthopedics education, Students, Medical statistics & numerical data
- Abstract
Introduction: Students seek gap years to enhance knowledge and improve chances of professional success. Although many institutions offer research opportunities, no studies have examined outcomes after these experiences. This study evaluates a dedicated year of orthopaedic research on a cohort's ultimate orthopaedic surgery match rate., Methods: From 2001 to 2018, 129 learners spent a year with our Department of Orthopedic Surgery at a major academic medical center. The students were either completing a gap year after college, during or after medical school, or after an unsuccessful match. Participants were asked to respond to a survey, which included demographics, educational information, and metrics related to the program. For the subcohort of students who ranked orthopaedic surgery, the match rate was compared with the mean for the US orthopaedic surgery match rates from 2006 to 2018 using a chi-square analysis. In addition, a Mann-Whitney U test was used to compare the number of publications before and after the year., Results: One hundred three students (80%) returned completed questionnaires. Of all learners who applied to and ranked orthopaedic surgery, 91% matched into an orthopaedic surgery residency program. These results compared favorably with the US orthopaedic match from 2006 to 2018 (67.9%; P < 0.001), despite a 4-point lower United States Medical Licensing Examination (USMLE) Step 1 score for the research cohort. Finally, the research cohort had a greater percentage of women (23%) and minorities (40%) than the proportion of woman and minority practicing orthopaedic surgeons., Conclusion: Students who completed a gap year in research matched into orthopaedics at a higher rate than the national average, despite a lower Step score. Mentors may also target traditionally underrepresented groups to help increase the pool of diverse applicants.
- Published
- 2020
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24. Perioperative Antibiotic Utilization by Orthopedic Surgeons in Arthroscopic Surgery A Survey of Practice Patterns.
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Anil U, Badri A, Pham H, Beutler G, Strauss E, Alaia M, Jazrawi L, and Campbell KA
- Subjects
- Humans, Surveys and Questionnaires, United States, Antibiotic Prophylaxis statistics & numerical data, Arthroscopy, Knee Joint surgery, Practice Patterns, Physicians' statistics & numerical data, Shoulder Joint surgery, Surgical Wound Infection prevention & control
- Abstract
Background: Given the relatively low incidence of infection, the role of prophylactic antibiotics for infection prevention in arthroscopic surgery is unclear. Without established evidence-based guidelines, it becomes important to understand the trends and common practices in the field., Hypothesis: We hypothesized that a majority of surgeons would use preoperative intravenous antibiotics and that postoperative antibiotics would be rarely used., Methods: A web-based link containing a questionnaire on perioperative antibiotic use for arthroscopic surgery of the knee and shoulder was sent to sports medicine surgeons at several institutions in the New York tri-state region. The questionnaire addressed antibiotic use both preoperatively and postoperatively and the type of medication used., Results: During the study period, 86 surgeons responded to the knee portion of the survey and 139 surgeons responded to the shoulder portion of the survey. A significant majority (94.24% for knee and 93.02% for shoulder) of the respondents routinely preferred to use preoperative intravenous antibiotics for both shoulder and knee surgery. The antibiotic of choice for a majority of the respondents was cefazolin (98.1% respondents). In patients with penicillin allergies, most preferred to use clindamycin. Most respondents (84.5%) did not routinely use postoperative oral antibiotics., Conclusion: There is significant consensus among orthopedic surgeons performing knee and shoulder arthroscopic surgery regarding use of preoperative antibiotics, with the majority routinely prescribing preoperative intravenous antibiotics for prophylaxis and cefazolin being the most commonly used antibiotic. The majority of surgeons prefer not to use postoperative oral antibiotics., Clinical Relevance: This study describes the current trends in the use of perioperative antibiotics among orthopedic surgeons for routine arthroscopic procedures in the shoulder and knee.
- Published
- 2020
25. Pain catastrophizing is associated with increased physical disability in patients with anterior knee pain.
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Thompson K, Kramarchuk M, Yagnatovsky M, Kunichoff D, Zacchilli M, Campbell KA, Alaia M, Jazrawi L, and Strauss E
- Abstract
Introduction: The traditional nociceptive approach to pain identifies the mind and body as functionally separate. However, the biopsychosocial model accounts for the impact of social, psychological and physical factors on the patient experience. The purpose of this study was to determine the relationship between diagnosis, physical disability, and psychological distress among patients with anterior knee pain-one of the most common complaints in an orthopedic clinic., Methods: This was a single-center, cross-sectional study. Patients presenting for initial evaluation of knee pain completed the Pain Catastrophizing Scale, Kujala Anterior Knee Pain Scale, and SF-12 questionnaires. Statistical analysis was performed using SPSS Version 24., Results: 207 patients, 108 (52.2%) females and 99 (47.8%) males, with a mean age 44.5 ± 15.4 years were enrolled. The osteoarthritis cohort had the highest pain catastrophizing score (17 ± 14.5), lowest Kujala score (48.3 ± 18.1), lowest SF-12 PCS (37.5 ± 8.3), and lowest SF-12 MCS (50.8 ± 11.0). Across all diagnoses, there was a statistically significant negative correlation between the total Pain Catastrophizing Score (PCS) and the Kujala, SF-12 Physical, and SF-12 Mental Component Scores. Bivariate and multivariate analysis demonstrated a correlation between PCS and duration of symptoms and African-Americans. The Kujala and SF-12 PCS demonstrated a statistically significant correlation with age, smoking, and the Asian Indian ethnicity. The SF-12 MCS showed a significant relationship with the Asian Indian ethnicity. Bivariate analysis also showed a statistically significant relationship between the SF-12 PCS and the SF-12 MCS., Conclusion: Knee pain patients presenting to an orthopedic sports medicine clinic demonstrate diminished physical quality of life and psychological reserves. This study determined an association between catastrophizing behavior and other patient reported outcomes measuring pain, physical distress, quality of life and mental/emotional well-being. To optimize patient outcomes, psychological domain should be managed contemporaneously to orthopedic pathology., (© 2020 Published by Elsevier B.V. on behalf of Professor P K Surendran Memorial Education Foundation.)
- Published
- 2020
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26. Everything pectoralis major: from repair to transfer.
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Thompson K, Kwon Y, Flatow E, Jazrawi L, Strauss E, and Alaia M
- Subjects
- Humans, Rupture diagnosis, Rupture etiology, Pectoralis Muscles injuries, Pectoralis Muscles surgery, Rupture surgery, Tendon Transfer
- Abstract
Background : Pectoralis major ruptures are increasing in incidence primarily due to an increase in awareness, activity level among young males between 20 and 40 years of age, and use of anabolic steroids. Although the majority of pectoralis major ruptures are acute injuries, many chronic ruptures are unrecognized and it is imperative to understand the proper evaluation of these injuries, as well as the appropriate treatment for acute and chronic ruptures. Purpose : Pectoralis major ruptures can lead to deformity and physical disability if left untreated. This review paper discusses both acute and chronic ruptures as well as indications for nonoperative treatment and operative treatment to give the reader the best understanding of this diagnosis and proper management. Methods : A systematic review of the literature was performed using a search of electronic databases. Search terms such as pectoralis major rupture, pectoralis major repair, pectoralis major tendon transfer , and pectoralis major nonoperative treatment were used. Case reports, systematic reviews, prospective and retrospective studies were included to provide a comprehensive review. The only exclusion criteria consisted of studies not published in English. This review article includes the anatomy and biomechanics of the pectoralis major muscle, proper evaluation of the patient, operative and nonoperative treatment of acute and chronic pectoralis major ruptures, and outcomes of the recommended treatment. Conclusion : Nonoperative treatment is indicated for patients with medical comorbidities, older age, incomplete tears, or irreparable damage. Patients treated non-operatively have been shown to lose strength, but regain full range of motion. Patients with surgery before 6 weeks reported better outcomes than patients with surgery between 6 and 8 weeks. The chronicity of the rupture (>8 weeks) increases the likelihood of reconstruction, involving the use of autografts or allografts. Patients treated with delayed repair had significantly better strength, satisfaction, and outcomes than patients with nonoperative treatment. The pectoralis tendon can also be transferred in patients with rotators cuff tears, atrophy, or significant functional limitation. Tendon transfers have been shown to have unpredictable outcomes, but overall satisfactory results.
- Published
- 2020
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27. Anterior Cruciate Ligament Ruptures in the Skeletally Immature Current State of the Art.
- Author
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Liu JX and Jazrawi L
- Subjects
- Adolescent, Bone Development, Child, Humans, Medical History Taking, Physical Examination, Risk Factors, Rupture, Anterior Cruciate Ligament Injuries surgery, Anterior Cruciate Ligament Reconstruction methods
- Abstract
Anterior cruciate ligament (ACL) injuries in children and adolescents are increasing every year. This patient population has unique risk factors and treatment considerations depending on specific patient factors and the level of bone maturity. This review summarizes the current data regarding pertinent features of the history and physical exam, indications for nonoperative management, assessment of skeletal maturity, and the surgical management of patients based on their unique physeal considerations. To prevent physeal injury, the surgical considerations differ from the adult population with respect to graft choice, location of fixation, reconstruction technique, and postoperative protocol. Orthopedic surgeons should be familiar with the various surgical techniques, graft selection choices, postoperative rehabilitation programs, controversies, and outcomes associated with the management of ACL injuries in the pediatric population.
- Published
- 2020
28. Clinical Outcomes after Mini-Open Excision of Popliteal Cysts.
- Author
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Snir N, Wolfson T, Pham H, Dai A, Sherman O, Feldman A, and Jazrawi L
- Subjects
- Arthroscopy statistics & numerical data, Female, Humans, Magnetic Resonance Imaging methods, Male, Middle Aged, Outcome and Process Assessment, Health Care, Range of Motion, Articular, Recovery of Function, Reoperation statistics & numerical data, United States epidemiology, Dissection adverse effects, Dissection methods, Knee Joint diagnostic imaging, Knee Joint surgery, Minimally Invasive Surgical Procedures adverse effects, Minimally Invasive Surgical Procedures methods, Popliteal Cyst diagnosis, Popliteal Cyst surgery, Postoperative Complications diagnosis, Postoperative Complications epidemiology, Postoperative Complications surgery
- Abstract
Purpose: The purpose of the study was to investigate clinical outcomes following a mini-open posterior technique., Methods: Patients who received mini-open popliteal cyst excisions between April 1999 and April 2010 were identified. Charts were retrospectively reviewed for postoperative complications, cyst recurrence, previous aspiration, re-operation, intraoperative findings, cyst size, comorbidities, and co-surgeries. Visual Analogue Pain Scale and Rauschning's symptomatic knee criteria were collected prospectively to assess functional outcomes., Results: Twenty-two legs in 21 patients were included in the study [males: 12 (57%); females: 9 (43%); age: 48.23 ± 11.74 years; BMI: 26.7 ± 4.54 kg/m2; follow-up: 4.55 ± 3.01 years]. Average cyst size was 4.16 ± 1.64 cm and were all located in the posteromedial aspect of the leg. All 22 cases had associated intra-articular pathology based on MRI, physical examination, and arthroscopy. Complications after cyst excision included: paresthesia in the distribution of the saphenous nerve (3/22, 14%), keloid formation (1/22, 4%), joint effusion requiring aspiration (1/22, 4%), and one recurrence requiring cystectomy 10 years later (4%). All incidences of paresthesia resolved. Mean visual analog pain score decreased by 6 points (p < 0.001) and Rauschning and Lindgren score decreased by two categories, from a 2.6 (category 2-3) preoperatively to 0.6 (category 0-1) postoperatively (p < 0.001)., Conclusion: Mini-open popliteal cyst excision is a safe and effective technique for refractory popliteal cysts in patients who desire a decrease in pain, an increase range of motion, and improved function in knee flexion and extension. Further studies are needed to evaluate the clinical outcomes of patients over a longer duration as our one patient with a 10-year follow-up required a repeat procedure.
- Published
- 2019
29. The Anterolateral Ligament (ALL) The New Ligament?
- Author
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Capogna BM, Kester BS, Shenoy K, Jazrawi L, Strauss EJ, and Alaia MJ
- Subjects
- Anterior Cruciate Ligament diagnostic imaging, Anterior Cruciate Ligament physiopathology, Anterior Cruciate Ligament Injuries diagnostic imaging, Anterior Cruciate Ligament Injuries history, Anterior Cruciate Ligament Injuries physiopathology, Biomechanical Phenomena, History, 19th Century, History, 20th Century, History, 21st Century, Humans, Joint Instability diagnostic imaging, Joint Instability history, Joint Instability physiopathology, Knee Joint diagnostic imaging, Knee Joint physiopathology, Ligaments, Articular diagnostic imaging, Ligaments, Articular physiopathology, Range of Motion, Articular, Recovery of Function, Treatment Outcome, Anterior Cruciate Ligament surgery, Anterior Cruciate Ligament Injuries surgery, Anterior Cruciate Ligament Reconstruction adverse effects, Anterior Cruciate Ligament Reconstruction history, Joint Instability surgery, Knee Joint surgery, Ligaments, Articular surgery
- Abstract
Background: Despite advances in technology, graft rupture rates reported in the literature following anterior cruciate ligament (ACL) surgery range from 1.8% to 18%. Recent anatomical studies have identified a lateral structure, the anterolateral ligament (ALL), as a potential source of residual pivoting following ACL reconstruction. The purpose of this report is to review the history surrounding the ALL and recent anatomic studies, identify its biomechanical and clinical implications, and develop a practical approach to utilizing it during ACL reconstruction., Methods: An extensive review of the historical and current literature surrounding the identification of the ALL, its biomechanical function, reconstruction, and outcomes of ALL reconstruction was performed., Discussion: After the storm of media coverage surrounding the "new ligament" known as the ALL, much attention was focused on cadaveric dissection, biomechanical analysis, and reconstruction of this structure. Several techniques have been described, and currently studies are being performed both retrospectively and prospectively to evaluate the added benefit of ALL reconstruction to the rotational stability of the knee and outcomes after ACL reconstruction., Conclusion: The ALL is a lateral-based structure that provides rotational stability to the knee in the presence of ACL deficiency. Reconstruction of this ligament may provide added benefit to stability and outcomes following ACL reconstruction in certain patient populations. Further randomized controlled trials are needed to elucidate the true benefit of ALL reconstruction and those patients who should undergo this added procedure.
- Published
- 2019
30. MRI, arthroscopic and histopathologic cross correlation in biceps tenodesis specimens with emphasis on the normal appearing proximal tendon.
- Author
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Burke CJ, Mahanty SR, Pham H, Hoda S, Babb JS, Gyftopoulos S, Jazrawi L, and Beltran L
- Subjects
- Adult, Aged, Female, Humans, Male, Middle Aged, ROC Curve, Reproducibility of Results, Retrospective Studies, Shoulder Joint surgery, Tendinopathy surgery, Arthroscopy methods, Magnetic Resonance Imaging methods, Muscle, Skeletal diagnostic imaging, Shoulder Joint diagnostic imaging, Tendinopathy diagnosis, Tendons diagnostic imaging, Tenodesis methods
- Abstract
Purpose: To correlate the histopathologic appearances of resected long head of the biceps tendon (LHBT) specimens following biceps tenodesis, with pre-operative MRI and arthroscopic findings, with attention to the radiologically normal biceps., Material and Methods: Retrospective analysis of patients who had undergone preoperative MRI, subsequent arthroscopic subpectoral tenodesis for SLAP tears and histopathologic inspection of the excised sample between 2013 and 16. Those with a normal MRI appearance or mildly increased intrasubstance signal were independently analyzed by 2 blinded radiologists. A blinded orthopedic surgeon and pathologist reviewed all operative imaging and pathologic slides, respectively., Results: Twenty-three LHBT resected samples were identified on MRI as either normal (Reader 1 n = 15; Reader 2 n = 14) or demonstrating low-grade increased signal (Reader 1 n = 8; Reader 2 n = 9). Of these, 86.9% demonstrated a histopathological abnormality. 50% of samples with histopathological abnormality demonstrated normal appearance on MRI. The most common reported histopathology finding was myxoid degeneration (73.9%) and fibrosis (52.2%). The most common arthroscopic abnormality was fraying (18.2%) and erythema (13.6%). Utilizing histopathology as the gold standard, the two radiologists demonstrated a sensitivity of 35.0% v 42.9%, specificity of 66.7% v 100%, PPV of 87.5% v 100%, and NPV of 13.3% v 14.3%. Corresponding arthroscopic inspection demonstrated a sensitivity of 31.6%, specificity of 66.6%, PPV 85.7% and NPV of 13.3%. There was moderate agreement between the two radiologists, κ = 0.534 (95% CI, 0.177 to 0.891), p = 0.01., Conclusion: Histopathological features of low grade tendinosis including mainly myxoid degeneration and fibrosis are frequently occult on MR imaging., (Copyright © 2019 Elsevier Inc. All rights reserved.)
- Published
- 2019
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31. Orthobiologics A Comprehensive Review of the Current Evidence and Use in Orthopedic Subspecialties.
- Author
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Bravo D, Jazrawi L, Cardone DA, Virk M, Passias PG, Einhorn TA, and Leucht P
- Subjects
- Bone and Bones injuries, Humans, Sports Medicine methods, Sports Medicine trends, Wound Healing drug effects, Biological Products classification, Biological Products pharmacology, Orthopedics methods, Orthopedics trends
- Abstract
Orthobiologics are organic and synthetic materials that are used in and outside of the operating room to augment both bone and soft tissue healing. The orthobiologics portfolio has vastly expanded over the years, and it has become imperative for orthopedic surgeons to understand the role and function of this new class of biologic adjuvants. This review will highlight key components and product groups that may be relevant for the practicing orthopedic surgeon in any subspecialty. This by no means is an extensive list of the available products but provides an important overview of the most highlighted products available in the market today. Those discussed include, bone void fillers, extracelluar matrix (ECM) products, platelet-rich plasma (PRP), bone morphogenetic protein-2 (BMP-2), bone marrow aspirate (BMA), bone marrow aspirate concentrate (BMAC), and mesenchymal stem cells (MSCs). These are further categorized into their uses in several subspecialties including, traumatology, sports medicine, sports surgery, and spine surgery.
- Published
- 2018
32. Physical Therapy or Arthroscopic Surgery for Treatment of Meniscal Tears: Is Noninferiority Enough?
- Author
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Jazrawi L, Gold HT, and Zuckerman JD
- Subjects
- Humans, Magnetic Resonance Imaging, Medicine, Physical Therapy Modalities, Retrospective Studies, Arthroscopy, Knee Injuries
- Published
- 2018
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33. Clinical and radiologic evaluation of the posterior cruciate ligament-injured knee.
- Author
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Badri A, Gonzalez-Lomas G, and Jazrawi L
- Abstract
Purpose of Review: Accurate isolated PCL diagnosis continues to present a challenge. This article reviews the current literature regarding clinical and radiographic evaluation of PCL injuries., Recent Findings: A thorough history to understand the mechanism of injury should begin any evaluation. Several clinical tests have been shown to effectively assess PCL laxity, with the posterior drawer test possessing the highest sensitivity and specificity. Any thorough exam should compare the contralateral, uninjured leg. If a PCL or multi-ligament injury is suspected, plain radiographs should be performed to avoid missing a fracture or avulsion. An MRI represents the current gold standard for diagnosing ligament injuries in the knee and should always be obtained in these cases. Due to the significant incidence of nerve injuries (25%) and vascular injuries (18%) with knee dislocations, any suspicion of neurovascular compromise necessitates further studies. A combination of a thorough clinical history and examination, followed by appropriate imaging optimizes PCL and multi-ligament injury evaluation.
- Published
- 2018
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34. Editorial Commentary: Can We Really See the Calcified Cartilage Layer When Debriding Focal Cartilage Defects?
- Author
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Jazrawi L
- Subjects
- Cadaver, Humans, Knee Joint, Cartilage, Articular
- Abstract
Cell-based cartilage restoration techniques have made huge leaps in recent years; however, many hurdles still lay ahead, one of which is the fundamental task of preparing the cartilage lesion site. Although it is one of the first skills an arthroscopist learns during training, it seems that current techniques and instrumentation still yield inconsistent results, which can hinder patient outcomes., (Copyright © 2018 Arthroscopy Association of North America. Published by Elsevier Inc. All rights reserved.)
- Published
- 2018
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35. Clinical Utility of Continuous Radial Magnetic Resonance Imaging Acquisition at 3 T in Real-time Patellofemoral Kinematic Assessment: A Feasibility Study.
- Author
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Burke CJ, Kaplan D, Block T, Chang G, Jazrawi L, Campbell K, and Alaia M
- Subjects
- Adult, Biomechanical Phenomena physiology, Case-Control Studies, Feasibility Studies, Female, Humans, Joint Instability physiopathology, Male, Patellofemoral Joint physiopathology, Joint Instability diagnostic imaging, Magnetic Resonance Imaging methods, Patellofemoral Joint diagnostic imaging
- Abstract
Purpose: To compare patellar instability with magnetic resonance imaging analysis using continuous real-time radial gradient-echo (GRE) imaging in the assessment of symptomatic patients and asymptomatic subjects., Methods: Symptomatic patients with suspected patellofemoral maltracking and asymptomatic volunteers were scanned in real time by a radial 2-dimensional GRE sequence at 3 T in axial orientation at the patella level through a range of flexion-extension. The degree of lateral maltracking, as well as the associated tibial tubercle-trochlear groove distance and trochlea depth, was measured. Patellar lateralization was categorized as normal (≤2 mm), mild (>2 to ≤5 mm), moderate (>5 to ≤10 mm), or severe (>10 mm). The patellofemoral cartilage was also assessed according to the modified Outerbridge grading system., Results: The study included 20 symptomatic patients (13 women and 7 men; mean age, 36 ± 12.8 years) and 10 asymptomatic subjects (3 women and 7 men; mean age, 33.1 years). The mean time to perform the dynamic component ranged from 3 to 7 minutes. Lateralization in the symptomatic group was normal in 10 patients, mild in 1, moderate in 8, and severe in 1. There was no lateral tracking greater than 3 mm in the volunteer group. Lateral maltracking was significantly higher in symptomatic patients than in asymptomatic subjects (4.4 ± 3.7 mm vs 1.5 ± 0.71 mm, P = .007). Lateral tracking significantly correlated with tibial tubercle-trochlear groove distance (r = 0.48, P = .006). There was excellent agreement on lateral tracking between the 2 reviewers (intraclass correlation coefficient, 0.979; 95% confidence interval, 0.956-0.990)., Conclusions: The inclusion of a dynamic radial 2-dimensional GRE sequence is a rapid and easily performed addition to the standard magnetic resonance imaging protocol and allows dynamic quantitative assessment of patellar instability and lateral maltracking in symptomatic patients. With a paucity of reported data using this technique confirming that these results reach clinical significance, future work is required to determine how much lateral tracking is clinically significant., Level of Evidence: Level III, case control., (Copyright © 2017 Arthroscopy Association of North America. Published by Elsevier Inc. All rights reserved.)
- Published
- 2018
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36. Open 4-Compartment Fasciotomy for Chronic Exertional Compartment Syndrome of the Leg.
- Author
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Dai AZ, Zacchilli M, Jejurikar N, Pham H, and Jazrawi L
- Abstract
Chronic exertional compartment syndrome (CECS) is a significant source of lower extremity pain and morbidity in the athletic population. Although endoscopic techniques have been introduced, open fasciotomy remains the mainstay of surgical treatment because of the paucity of evidence in support of an endoscopic approach. The literature on surgical management of CECS is mixed, and overall success rates are modest at best. Optimizing surgical technique, including prevention of neurovascular injury and wound complications, can make a significant impact on the clinical outcome. Here we present our surgical technique, including pearls and pitfalls, for open 4-compartment fasciotomy for treatment of chronic exertional compartment syndrome.
- Published
- 2017
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37. Type IV hypersensitivity reactions following Dermabond adhesive utilization in knee surgery: A Report of Three Cases.
- Author
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Yagnatovsky M, Pham H, Rokito A, Jazrawi L, and Strauss E
- Subjects
- Adult, Diagnosis, Differential, Female, Humans, Hypersensitivity, Delayed etiology, Hypersensitivity, Delayed therapy, Infections diagnosis, Knee Injuries surgery, Male, Orthopedic Procedures methods, Postoperative Complications etiology, Postoperative Complications therapy, Retrospective Studies, Sutures, Adhesives adverse effects, Cyanoacrylates adverse effects, Hypersensitivity, Delayed diagnosis, Orthopedic Procedures adverse effects, Postoperative Complications diagnosis, Tissue Adhesives adverse effects
- Abstract
We retrospectively reviewed the records of 3 patients (3 knees) with a delayed type hypersensitivity reaction following Dermabond exposure after an orthopaedic knee procedure. Delayed hypersensitivity reactions are mediated by CD4+ helper T cells. The use of skin adhesives in place of traditional sutures is increasing in popularity given Dermabond's potential benefits of decreased wound infection rate and better wound approximation. However, hypersensitivity reactions to the cyanoacrylate material in Dermabond have been described. Differentiating hypersensitivity reactions from post-operative infections is important as septic arthritis is a potentially devastating complication. This case series presents the challenge of properly diagnosing and managing hypersensitivity reactions. Consultation with allergists and dermatologists may be appropriate for ascertaining the nature of the surgical site complication and proper management. The recommended management of hypersensitivity-type reactions is a course of topical steroids and infection work up if needed.
- Published
- 2017
- Full Text
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38. The Impact of Body Mass Index on Outcomes Following Open Sub-Pectoralis Major Biceps Tenodesis.
- Author
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Rossy W, McGee A, Shamah S, Lepkowsky E, Alaia M, Jazrawi L, and Strauss E
- Subjects
- Adult, Aged, Arm, Body Mass Index, Female, Humans, Male, Middle Aged, Muscle, Skeletal, Retrospective Studies, Tendinopathy complications, Tenotomy, Treatment Outcome, Young Adult, Obesity complications, Tendinopathy surgery, Tenodesis
- Abstract
Purpose: Traditionally, biceps tenotomy has been recommended for obese, older, and less active patient populations, while tenodesis is preferred in younger, thinner, and more active individuals. In an effort to better understand the impact obesity has on the surgical management of long head of the biceps tendinopathy, the current study analyzed the effect body mass index had on surgical outcomes following open subpectoralis major biceps tenodesis., Methods: Patients who underwent biceps tenodesis between June 2006 and December 2013 were identified from our institution's surgical database. They were then contacted to assess their functional outcomes using validated outcome measures. Comparisons were made between the outcomes seen in obese patients (BMI ≥ 30) and non-obese patients (BMI < 30) with subgroup analyses looking at gender, age, and length of follow-up., Results: One hundred and twenty-two patients completed a follow-up assessment with a mean follow-up of 29.3 months. The non-obese cohort was composed of 84 patients with a mean BMI of 25.8. The obese cohort was composed of 38 patients with a mean BMI of 33.4. No significant difference was noted to be present with respect to postoperative outcome measures. Regression analysis with BMI as an independent variable demonstrated poor correlation with outcome measures., Conclusions: The results of the current study support open subpectoralis biceps tenodesis as an acceptable option for the treatment of LHB pathology irrespective of the treated patient's body mass index. Both obese and non-obese patients demonstrated low postoperative DASH scores and high Oxford Shoulder scores.
- Published
- 2017
39. Distal femoral varus osteotomy for unloading valgus knee malalignment: a biomechanical analysis.
- Author
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Quirno M, Campbell KA, Singh B, Hasan S, Jazrawi L, Kummer F, and Strauss EJ
- Subjects
- Aged, Biomechanical Phenomena, Cadaver, Humans, Knee Joint surgery, Middle Aged, Osteoarthritis, Knee surgery, Pressure, Tibia surgery, Femur surgery, Knee Joint physiology, Osteotomy methods
- Abstract
Purpose: To investigate the biomechanical properties of the load shifting following opening-wedge distal femoral varus osteotomies (DFVOs) and determine the osteotomy correction needed to unload the lateral compartment., Methods: Five human cadaveric knees were tested with a load of 500 N of axial compression. Medial and lateral tibiofemoral compartment contact area and pressure were assessed utilizing a modified F-scan pressure-sensitive sensor. The knees were tested in their baseline anatomic alignment, 10° valgus malalignment and following corrective DFVOs of 5°, 10° and 15°. The load shifting effect of the various DFVO correction angles was analysed using a one-way ANOVA to determine the correction angle necessary to unload the lateral compartment., Results: Gradually shifting the loading vector medially with increasing DFVO angles resulted in a decrease in the mean contact area and mean contact pressures in the lateral compartment with progressive increases in the medial compartment. The largest reduction in lateral compartment pressure and contact area was seen with the 15° osteotomy with a 25 % decrease in mean contact pressure and 20 % decrease in mean maximum contact pressure and mean contact area when compared to the 10° valgus-malaligned knee. For the 10° valgus knee, a 15° correction resulted in near-normal contact pressures and areas compared with the knee in normal anatomic alignment., Conclusion: Progressive unloading of the lateral tibiofemoral compartment occurred with increasing DFVO correction angles. Clinically, when performing a DFVO for valgus malalignment, surgeons should consider overcorrecting the osteotomy by 5° to restore near-normal contact pressures and contact areas in the lateral compartment rather than the traditional teaching of correcting to neutral alignment.
- Published
- 2017
- Full Text
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40. Autograft Choice in Young Female Patients: Patella Tendon versus Hamstring.
- Author
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Shakked R, Weinberg M, Capo J, Jazrawi L, and Strauss E
- Subjects
- Adolescent, Adult, Age Factors, Female, Humans, Retrospective Studies, Sex Factors, Transplantation, Autologous, Treatment Outcome, Young Adult, Anterior Cruciate Ligament Injuries surgery, Anterior Cruciate Ligament Reconstruction methods, Hamstring Tendons transplantation, Patellar Ligament transplantation
- Abstract
With the increasing incidence of anterior cruciate ligament (ACL) reconstruction in women and younger patients, the optimal graft choice in the young female patient has become the subject of much debate. This study aimed to evaluate patient-reported outcomes, objective knee stability, complication rates, and the incidence of failure after ACL reconstruction using bone-patellar tendon-bone (BPTB) autograft compared with hamstring (HS) autograft in young female patients. Female patients who underwent primary ACL reconstruction with BPTB or HS autograft between ages 15 and 25 years were identified. Medical records were reviewed for postoperative complications and subsequent procedures on the operative knee. Patients were evaluated with functional surveys, physical examination including Lachman and pivot-shift tests, and arthrometric testing with a KT-1000 arthrometer. There were 37 patients in the BPTB group and 28 patients in the HS group. For patients who did not undergo revision, significant differences were not found in visual analog score ( p = 0.94), Lysholm score ( p = 0.81), Kujala score ( p = 0.85), or Tegner level ( p = 0.81). No difference was detected in the rate of return to a level of activity at or above the same level prior to injury ( p = 0.31). Significantly more patients in the BPTB group were graded 1a Lachman and negative pivot shift compared with the HS group ( p < 0.001). There was a significant difference in mean side-to-side manual maximum arthrometric testing ( p < 0.001). There were significantly fewer subsequent procedures and a lower rate of graft failures in the BPTB group. We detected no difference in subjective functional outcomes following ACL reconstruction. However, a higher failure rate in the HS reconstructions and greater laxity by arthrometric testing may indicate increased objective stability with the use of BPTB autograft in the young female patient population. The level of evidence for this article is (level III, retrospective cohort)., (Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.)
- Published
- 2017
- Full Text
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41. Clinical outcomes of ACL reconstruction with tibialis anterior allograft using an anteromedial portal approach.
- Author
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Capo J, Shamah SD, Jazrawi L, and Strauss E
- Subjects
- Adult, Aged, Female, Humans, Male, Middle Aged, Recovery of Function, Retrospective Studies, Treatment Outcome, Anterior Cruciate Ligament Injuries surgery, Anterior Cruciate Ligament Reconstruction methods, Tendons transplantation
- Published
- 2016
- Full Text
- View/download PDF
42. Physician Training Ultrasound and Accuracy of Diagnosis in Rotator Cuff Tears.
- Author
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Day M, Phil M, McCormack RA, Nayyar S, and Jazrawi L
- Subjects
- Arthroscopy, Clinical Competence, Humans, Learning Curve, Magnetic Resonance Imaging, Physical Examination, Predictive Value of Tests, Prospective Studies, Reproducibility of Results, Education, Medical, Continuing methods, Inservice Training methods, Orthopedic Surgeons education, Orthopedics education, Rotator Cuff Injuries diagnostic imaging, Sports Medicine education, Ultrasonography
- Abstract
Introduction: Ultrasonography offers a fast and inexpensive method to evaluate the rotator cuff in the office setting. However, the accuracy of ultrasound is highly user dependent. The purpose of this study is to investigate the learning curve of an orthopaedic surgeon in using ultrasound to diagnose rotator cuff tears., Methods: A sports medicine fellowship trained orthopaedic surgeon was taught how to perform and interpret an ultrasound examination of the shoulder by a musculoskeletal radiologist. In this prospective study, subjects were patients who presented to the office with shoulder pain suspected to be consistent with rotator cuff pathology, either complete or partial tears. The surgeon was blinded to magnetic resonance imaging (MRI) results and performed the ultrasound after performing a physical exam. Based on ultrasound and exam, the surgeon assessed if the rotator cuff was intact (no tear) or torn (having a partial or full thickness tear). Results were compared to MRI findings and arthroscopic findings (when available), and accuracy was evaluated over time to determine overall accuracy and if significant learning and improvement in accuracy took place over the time period studied., Results: Eighty patients were enrolled in the study; seventy-four had an MRI within 3 months of the ultrasound and were available for evaluation. Nineteen patients underwent ultrasound, MRI, and arthroscopy. Ultrasound was able to accurately diagnose the correct rotator cuff pathology (no tear, a partial thickness tear, or a full thickness tear) in 61% of patients. Ultrasound accurately diagnosed simply the presence or absence of a tear in 74% of patients. There was a general trend toward improved accuracy as the investigator gained experience, with accuracy rates of approximately 51% for the first 40 patients, and 69% for the last 40 patients evaluated, although this difference was not statistically significant (p = 0.154)., Discussion: Ultrasound imaging requires significant training and practice to provide a clinically useful level of diagnostic accuracy. The applicability of this procedure for diagnosing primary rotator cuff tears in an orthopaedic office setting may be limited by the time and volume required for the practitioner to approach the accuracy reported for diagnostic ultrasound and MRI in the literature.
- Published
- 2016
43. Cost effectiveness of meniscal allograft for torn discoid lateral meniscus in young women.
- Author
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Ramme AJ, Strauss EJ, Jazrawi L, and Gold HT
- Subjects
- Adult, Arthroplasty, Replacement, Knee statistics & numerical data, Female, Follow-Up Studies, Humans, Male, Markov Chains, Menisci, Tibial surgery, United States, Allografts, Cost-Benefit Analysis, Meniscus transplantation, Tibial Meniscus Injuries surgery
- Abstract
Objective: A discoid meniscus is more prone to tears than a normal meniscus. Patients with a torn discoid lateral meniscus are at increased risk for early onset osteoarthritis requiring total knee arthroplasty (TKA). Optimal management for this condition is controversial given the up-front cost difference between the two treatment options: the more expensive meniscal allograft transplantation compared with standard partial meniscectomy. We hypothesize that meniscal allograft transplantation following excision of a torn discoid lateral meniscus is more cost-effective compared with partial meniscectomy alone because allografts will extend the time to TKA., Methods: A decision analytic Markov model was created to compare the cost effectiveness of two treatments for symptomatic, torn discoid lateral meniscus: meniscal allograft and partial meniscectomy. Probability estimates and event rates were derived from the scientific literature, and costs and benefits were discounted by 3%. One-way sensitivity analyses were performed to test model robustness., Results: Over 25 years, the partial meniscectomy strategy cost $10,430, whereas meniscal allograft cost on average $4040 more, at $14,470. Partial meniscectomy postponed TKA an average of 12.5 years, compared with 17.30 years for meniscal allograft, an increase of 4.8 years. Allograft cost $842 per-year-gained in time to TKA., Conclusion: Meniscal allografts have been shown to reduce pain and improve function in patients with discoid lateral meniscus tears. Though more costly, meniscal allografts may be more effective than partial meniscectomy in delaying TKA in this model. Additional future long term clinical studies will provide more insight into optimal surgical options.
- Published
- 2016
- Full Text
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44. Osteochondral Proximal Tibial and Lateral Meniscal Allograft Transplant.
- Author
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Gonzalez-Lomas G, Dold AP, Kaplan DJ, Fralinger DJ, and Jazrawi L
- Abstract
Knee pain in young, active patients with meniscus-deficient knees and articular cartilage damage can present a challenge to treatment. Meniscal allograft transplantation (MAT) has shown good clinical results as treatment for meniscus deficiency; however, worse outcomes have been observed in patients with significant chondral damage. The development of chondral restorative techniques such as osteochondral allograft transplantation (OCA) has expanded the population of patients who may benefit from MAT. We present a case of proximal tibial osteochondral and lateral meniscal allograft transplant. This review includes a sample of patient examinations and imaging, followed by a detailed technical description of the case. The technique article concludes with a discussion on the niche combined MAT-OCA procedures occupy in the patient treatment realm.
- Published
- 2016
- Full Text
- View/download PDF
45. Evaluation, Treatment, and Outcomes of Meniscal Root Tears: A Critical Analysis Review.
- Author
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Strauss EJ, Day MS, Ryan M, and Jazrawi L
- Subjects
- Cartilage Diseases, Humans, Knee Injuries, Menisci, Tibial, Tibial Meniscus Injuries diagnosis, Arthroscopy, Tibial Meniscus Injuries surgery
- Abstract
Meniscal root tears or avulsions compromise the biomechanical function of the menisci to a greater extent than simple meniscal tears do. As such, if left untreated, root injuries render the menisci incapable of properly distributing axial load and resisting rotation and translation. The clinical diagnosis of meniscal root abnormalities may be difficult as the signs and symptoms typically associated with meniscal body injuries, such as mechanical locking and catching, may not be present in patients with root injury and there may not be a history of an acute traumatic event. Treating practitioners need to have a high suspicion for meniscal root abnormalities in patients presenting with joint line tenderness and pain with deep flexion activities. Magnetic resonance imaging (MRI) signs indicative of meniscal root abnormality include a radial tear of the meniscal root (on axial imaging), a vertical linear defect in the meniscal root (truncation sign on coronal imaging), meniscal extrusion >3 mm outside the peripheral margin of the joint (on coronal imaging), and increased signal within the meniscal root (ghost sign on sagittal sequences). Two main approaches for meniscal root repair have evolved. One approach involves the use of a transtibial pullout technique, and the other involves the use of a suture anchor repair. The goal of both approaches is to restore an anatomical attachment of the meniscal root to bone that is capable of converting axial weight-bearing loads into hoop stresses. In a recent systematic review of meniscal root repairs, healing (partial and complete) was reported to have occurred in 96% of cases, with all studies demonstrating improvements in terms of subjective and functional scores at a mean of 30.2 months postoperatively.
- Published
- 2016
- Full Text
- View/download PDF
46. Can Flexible Instruments Create Adequate Femoral Tunnel Lengths at 90° of Knee Flexion in Anterior Cruciate Ligament Reconstruction?
- Author
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Kalra K, Tang E, Atanda A, Khatib O, Shamah S, Meislin R, and Jazrawi L
- Subjects
- Aged, Aged, 80 and over, Anatomic Landmarks, Anterior Cruciate Ligament diagnostic imaging, Anterior Cruciate Ligament innervation, Biomechanical Phenomena, Cadaver, Equipment Design, Femur diagnostic imaging, Femur innervation, Humans, Knee Joint diagnostic imaging, Knee Joint innervation, Middle Aged, Pliability, Range of Motion, Articular, Anterior Cruciate Ligament surgery, Anterior Cruciate Ligament Reconstruction instrumentation, Femur surgery, Knee Joint surgery, Surgical Instruments
- Abstract
Purpose: This study aims to study femoral tunnel lengths drilled with a flexible reamer and the distance to important lateral structures obtained by flexing the knee at various angles and by drilling the guide pins arthroscopically to resemble clinical practice. The purpose of this cadaveric study was twofold: 1. to determine whether femoral tunnel lengths of greater than 20 mm can be created with a flexible reamer system at 90 ° of knee flexion and 2. to determine whether the lateral structures of the knee are safe with this technique., Methods: Ten fresh cadaveric knees were utilized. The intra-osseous length can be measured with a specially de - signed flexible guide pin. Flexible pins were inserted with the knee at 70°, 90°, and 120° of flexion. The intra-osseous length was measured with the measuring device. Each speci - men was dissected around the lateral aspect of the knee to identify the critical structures, the common peroneal nerve, and the LCL. The distance from the guide pins to the com - mon peroneal nerve and femoral attachment of the LCL were measured with a standard flexible paper ruler to the nearest millimeter., Results: There is a trend for progressively increasing mean intra-osseous length associated with increased flexion of the knee. The mean intra-osseous length for 70° flexion was 25.2 mm (20 mm to 32 mm), which was statistically significant when compared to mean intra-osseous lengths of 32.1 mm (22 mm to 45 mm) and 38.0 mm (34 mm to 45 mm) in the 90° and 120° flexion groups, respectively (p < 0.05). There were no significant differences among the groups with respect to distance to the LCL. There is a trend toward longer distances to the common peroneal nerve with increased flexion. There was a statistically significant dif - ference when comparing 120° versus 70° (p < 0.05)., Conclusions: This study that shows that adequate femoral tunnel lengths can be safely created without knee hyperflex - ion using flexible instruments via an anteromedial portal.
- Published
- 2016
47. Comparison of Collagen Graft Fixation Methods in the Porcine Knee: Implications for Matrix-Assisted Chondrocyte Implantation and Second-Generation Autologous Chondrocyte Implantation.
- Author
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Whyte GP, McGee A, Jazrawi L, and Meislin R
- Subjects
- Animals, Models, Animal, Swine, Collagen, Fibrin Tissue Adhesive, Stifle surgery, Sutures, Tissue Adhesives, Tissue Scaffolds
- Abstract
Purpose: To evaluate the fixation integrity at time zero of a type I/III collagen patch secured to a chondral defect in the porcine knee using methods typically employed in autologous chondrocyte implantation (ACI) and matrix-assisted chondrocyte implantation., Methods: Twenty-four porcine knee specimens underwent a medial parapatellar arthrotomy. A prefabricated template was used to create cartilage defects of 2 cm(2) in the medial femoral condyle. A size-matched collagen patch was fashioned. Four methods of fixation to the chondral defect were analyzed: group 1-saline, group 2-fibrin glue around the periphery of the patch, group 3-fibrin glue applied to the base of the defect and around the periphery of the patch, group 4-6-0 vicryl suture and fibrin glue around the periphery of the patch. Collagen patch fixation was assessed at intervals of 60, 300, 600, 900, and 1,200 cycles from full extension to 90° of flexion, performed manually without application of axial force. Patch fixation was evaluated by 2 independent observers using a customized scoring scale., Results: Mean peripheral detachment of the patch and chondral defect uncovering remained less than 25% for all groups. Area of defect uncovering was significantly increased in group 2 compared with group 4 after 900 and 1,200 cycles (P = .0014 and P = .0025, respectively). Fibrin glue applied to the base of the defect, or suturing of the patch, reduced deformation significantly after 900 cycles., Conclusions: Suture increases the stability of fixation of a type I/III collagen patch to a chondral defect better than fibrin glue alone in the porcine knee after repetitive cycling, with respect to patch detachment and chondral defect uncovering. Application of fibrin glue to the base of the defect, or securing the patch with suture, decreases collagen patch deformation., Clinical Relevance: In cases where minimally invasive techniques do not allow suture fixation of the collagen patch, scaffold fixation may be compromised during articular motion protocols typically used after second- and third-generation ACI procedures., (Copyright © 2016 Arthroscopy Association of North America. Published by Elsevier Inc. All rights reserved.)
- Published
- 2016
- Full Text
- View/download PDF
48. Bone Marrow Edema: Chronic Bone Marrow Lesions of the Knee and the Association with Osteoarthritis.
- Author
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Collins JA, Beutel BG, Strauss E, Youm T, and Jazrawi L
- Subjects
- Chronic Disease, Disease Progression, Humans, Magnetic Resonance Imaging, Osteoarthritis, Knee therapy, Bone Marrow Diseases pathology, Bone Marrow Diseases therapy, Edema pathology, Edema therapy, Osteoarthritis, Knee pathology
- Abstract
Bone marrow edema of the knee occurs secondary to a myriad of causes. The hallmark of a bone marrow lesion (BML) is an area of decreased signal intensity on T1 weighted MRI with a corresponding area of increased signal intensity on a T2 weighted MRI. Recently, chronic bone marrow lesions have been correlated with knee pain and progression of osteoarthritis. These lesions have also been associated with other degenerative conditions such as meniscal tears, cartilage deterioration, subchondral cyst formation, mechanical malalignment, and ultimately progression to arthroplasty. Medical treatments, such as prostacyclin and bisphosphonate therapy, have shown promise. Alignment procedures, as well as core decompression and subchondroplasty, have been used as surgical treatments for chronic BMLs.
- Published
- 2016
49. Rotator cuff tear shape characterization: a comparison of two-dimensional imaging and three-dimensional magnetic resonance reconstructions.
- Author
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Gyftopoulos S, Beltran LS, Gibbs K, Jazrawi L, Berman P, Babb J, and Meislin R
- Subjects
- Female, Humans, Lacerations surgery, Male, Middle Aged, Retrospective Studies, Rotator Cuff surgery, Rupture diagnostic imaging, Rupture surgery, Single-Blind Method, Tendon Injuries surgery, Tomography, X-Ray Computed, Imaging, Three-Dimensional, Lacerations diagnostic imaging, Magnetic Resonance Imaging methods, Rotator Cuff Injuries, Tendon Injuries diagnostic imaging
- Abstract
Background: The purpose of this study was to see if 3-dimensional (3D) magnetic resonance imaging (MRI) could improve our understanding of rotator cuff tendon tear shapes. We believed that 3D MRI would be more accurate than two-dimensional (2D) MRI for classifying tear shapes., Methods: We performed a retrospective review of MRI studies of patients with arthroscopically proven full-thickness rotator cuff tears. Two orthopedic surgeons reviewed the information for each case, including scope images, and characterized the shape of the cuff tear into crescent, longitudinal, U- or L-shaped longitudinal, and massive type. Two musculoskeletal radiologists reviewed the corresponding MRI studies independently and blind to the arthroscopic findings and characterized the shape on the basis of the tear's retraction and size using 2D MRI. The 3D reconstructions of each cuff tear were reviewed by each radiologist to characterize the shape. Statistical analysis included 95% confidence intervals and intraclass correlation coefficients., Results: The study reviewed 34 patients. The accuracy for differentiating between crescent-shaped, longitudinal, and massive tears using measurements on 2D MRI was 70.6% for reader 1 and 67.6% for reader 2. The accuracy for tear shape characterization into crescent and longitudinal U- or L-shaped using 3D MRI was 97.1% for reader 1 and 82.4% for reader 2. When further characterizing the longitudinal tears as massive or not using 3D MRI, both readers had an accuracy of 76.9% (10 of 13). The overall accuracy of 3D MRI was 82.4% (56 of 68), significantly different (P = .021) from 2D MRI accuracy (64.7%)., Conclusion: Our study has demonstrated that 3D MR reconstructions of the rotator cuff improve the accuracy of characterizing rotator cuff tear shapes compared with current 2D MRI-based techniques., (Copyright © 2016 Journal of Shoulder and Elbow Surgery Board of Trustees. Published by Elsevier Inc. All rights reserved.)
- Published
- 2016
- Full Text
- View/download PDF
50. Reply to letter to the editor: subchondral calcium phosphate is ineffective for bone marrow edema lesions in adults with advanced osteoarthritis.
- Author
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Chatterjee D, McGee A, Strauss E, Youm T, and Jazrawi L
- Subjects
- Female, Humans, Male, Bone Marrow Diseases drug therapy, Calcium Phosphates administration & dosage, Edema drug therapy, Edema etiology, Osteoarthritis complications
- Published
- 2015
- Full Text
- View/download PDF
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