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Your search keyword '"Javornik, Noreen B."' showing total 6 results
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6 results on '"Javornik, Noreen B."'

5. Reproducibility of Gradings of Retinal Photographs in Eyes with Subfoveal Choroidal Neovascularization and Age-Related Macular Degeneration in the Macular Photocoagulation Study.

Author

Jefferys, Joan L., Alexander, Judith, Hiner, Cheryl J., Javornik, Noreen B., Smith, Rochelle E., Bressler, Neil M., and Hawkins, Barbara S.

Subjects
RETINAL degeneration, RETINAL diseases, LIGHT amplifiers, OPTICAL parametric oscillators, NEOVASCULARIZATION, BLOOD-vessel development
Abstract

Purpose: To assess the reproducibility of the evaluation of color photographs and fluorescein angiograms of the macula of each eye for patients enrolled in the Macular Photocoagulation Study (MPS) trials of laser photocoagulation of subfoveal choroidal neovascularization (CNV) secondary to age-related macular degeneration. Methods: A total of 65 pre-enrollment and 26 posttreatment sets of photographs were regraded. The two gradings were compared on selected items judged to be of primary importance with respect to the role of the MPS Reading Center. Results: Agreement on eligibility of the neovascular lesion for an MPS trial was 88% (kappa statistic = 0.59); agreement on the size of the lesion was 86% (kappa statistic = 0.80); agreement on whether the lesion was covered by heavy treatment was 69% (kappa statistic = 0.35); and agreement on whether the treatment was in compliance with the study protocol was 73% (kappa statistic = 0.06). Conclusions: Interpretation of photographs of eyes with CNV secondary to age-related macular degeneration for eligibility and size of the lesion was reproducible in the MPS. However, adequacy of laser photocoagulation treatment could not be determined reliably from photographs. [ABSTRACT FROM AUTHOR]

Published
2008
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6. Treatment of Subfoveal Choroidal Neovascularization-Reply

Author

Maguire, Maureen G., Fine, Stuart L., Folk, James C., Bressler, Neil M., Javornik, Noreen B., Alexander, Judith, Chandra, Suresh, and Schachat, Andrew P.

Abstract

IN REPLY We thank Dr Tiedeman for his careful reading of our article and his thoughtful comments. As we emphasized in our discussion, advising whether a particular patient should be treated with laser photocoagulation involves consideration of both short- and long-term effects of the treatment and characteristics of the patient such as the condition of the fellow eye. We and Dr Tiedeman are in agreement that the reason that group B patients are good candidates for immediate treatment is the reduced risk for severe loss of vision that begins at 12 months after treatment and endures for at least 3 additional years. This sustained period of lower risk for loss of vision outweighs, in our opinion, the period of increased risk immediately following treatment.Members of the Macular Photocoagulation Study Group are listed in the April issue of the Archives on page 482.

Published
1995
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