298 results on '"Jauch, Ralf"'
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2. Highly cooperative chimeric super-SOX induces naive pluripotency across species
3. Mutations involving the SRY-related gene SOX8 are associated with a spectrum of human reproductive anomalies
4. BRD8 guards the pluripotent state by sensing and maintaining histone acetylation
5. Advancements in personalized stem cell models for aging-related neurodegenerative disorders
6. Highly cooperative chimeric super-SOX induces naive pluripotency across species
7. Pathogenic variants in the DEAH-box RNA helicase DHX37 are a frequent cause of 46,XY gonadal dysgenesis and 46,XY testicular regression syndrome
8. OCT4 interprets and enhances nucleosome flexibility
9. An engineered Sox17 induces somatic to neural stem cell fate transitions independently from pluripotency reprogramming
10. Evaluation of the determinants for improved pluripotency induction and maintenance by engineered SOX17
11. Correction: Pharmacological targeting of the transcription factor SOX18 delays breast cancer in mice
12. Small-Molecule Inhibitors of the SOX18 Transcription Factor
13. JMJD3 acts in tandem with KLF4 to facilitate reprogramming to pluripotency
14. Diversity among POU transcription factors in chromatin recognition and cell fate reprogramming
15. Capturing the interactome of newly transcribed RNA
16. Evaluation of the determinants for improved pluripotency induction and maintenance by engineered SOX17
17. Pluripotency reprogramming by competent and incompetent POU factors uncovers temporal dependency for Oct4 and Sox2
18. Evolutionary Landscape of SOX Genes to Inform Genotype-to-Phenotype Relationships
19. The homeodomain of Oct4 is a dimeric binder of methylated CpG elements
20. Modulating the epigenetic state promotes the reprogramming of transformed cells to pluripotency in a line-specific manner
21. Changing POU dimerization preferences converts Oct6 into a pluripotency inducer
22. The homeodomain of Oct4 is a dimeric binder of methylated CpG elements
23. The chemical reprogramming of unipotent adult germ cells towards authentic pluripotency and de novo establishment of imprinting
24. SOX9 and SOX10 control fluid homeostasis in the inner ear for hearing through independent and cooperative mechanisms
25. Enhancing Sox/Oct cooperativity induces higher-grade developmental reset
26. The chemical reprogramming of unipotent adult germ cells towards authentic pluripotency and de novo establishment of imprinting.
27. Oct4 switches partnering from Sox2 to Sox17 to reinterpret the enhancer code and specify endoderm
28. Transposable element sequence fragments incorporated into coding and noncoding transcripts modulate the transcriptome of human pluripotent stem cells
29. The chromatin accessibility landscape reveals distinct transcriptional regulation in the induction of human primordial germ cell-like cells from pluripotent stem cells
30. Directed Evolution of an Enhanced POU Reprogramming Factor for Cell Fate Engineering
31. Cancer-associated missense mutations enhance the pluripotency reprogramming activity of OCT4 and SOX17
32. Expanding DSD Phenotypes Associated with Variants in the DEAH-Box RNA Helicase DHX37
33. SOX17 in cellular reprogramming and cancer
34. TherMos: Estimating protein–DNA binding energies from in vivo binding profiles
35. Distinct transcriptional regulatory modules underlie STAT3ʼs cell type-independent and cell type-specific functions
36. Structural analysis and dimerization profile of the SCAN domain of the pluripotency factor Zfp206
37. Deciphering the Sox-Oct partner code by quantitative cooperativity measurements
38. Structural basis for the cooperative DNA recognition by Smad4 MH1 dimers
39. FOXA1 Mutations Reveal Distinct Chromatin Profiles and Influence Therapeutic Response in Breast Cancer
40. Abstract 3439: FOXA1 mutations reveal distinct chromatin profiles and influence therapeutic response in breast cancer
41. Transposable Element-Gene Splicing Modulates the Transcriptional Landscape of Human Pluripotent Stem Cells
42. IL10RA Modulates Crizotinib Sensitivity in NPM1-ALK-positive Anaplastic Large Cell Lymphoma
43. Concurrent binding to DNA and RNA facilitates the pluripotency reprogramming activity of Sox2
44. Decision letter: Sequentially induced motor neurons from human fibroblasts facilitate locomotor recovery in a rodent spinal cord injury model
45. Structure of Smad1 MH1/DNA complex reveals distinctive rearrangements of BMP and TGF-β effectors
46. Evolution of the Vertebrate Gene Regulatory Network Controlled by the Transcriptional Repressor REST
47. SCIENTISTS & SOCIETIES: Horizons in Molecular Biology
48. Cancer‐associated missense mutations enhance the pluripotency reprogramming activity of OCT4 and SOX17
49. Cell fate reprogramming through engineering of native transcription factors
50. Directed Evolution of Reprogramming Factors by Cell Selection and Sequencing
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