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2. The statistical analysis plan for the unification of treatments and interventions for tinnitus patients randomized clinical trial (UNITI-RCT)

Author

Simoes, Jorge Piano, Schoisswohl, Stefan, Schlee, Winfried, Basso, Laura, Bernal-Robledano, Alberto, Boecking, Benjamin, Cima, Rilana, Denys, Sam, Engelke, Milena, Escalera-Balsera, Alba, Gallego-Martinez, Alvaro, Gallus, Silvano, Kikidis, Dimitris, López-Escámez, Jose A., Marcrum, Steven C., Markatos, Nikolaos, Martin-Lagos, Juan, Martinez-Martinez, Marta, Mazurek, Birgit, Vassou, Evgenia, Jarach, Carlotta Micaela, Mueller-Locatelli, Nicolas, Neff, Patrick, Niemann, Uli, Omar, Hafez Kader, Puga, Clara, Schleicher, Miro, Unnikrishnan, Vishnu, Perez-Carpena, Patricia, Pryss, Rüdiger, Robles-Bolivar, Paula, Rose, Matthias, Schecklmann, Martin, Schiele, Tabea, Schobel, Johannes, Spiliopoulou, Myra, Stark, Sabine, Vogel, Carsten, Wunder, Nina, Zachou, Zoi, and Langguth, Berthold

Published
2023
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3. COVID-19 pandemic impact on mental health in a large representative sample of older adults from the Lombardy region, Italy

Author

Bosetti, Cristina, Jarach, Carlotta Micaela, Santucci, Claudia, Amore, Mario, De Sena, Roberto, Ghislandi, Simone, Wang, Yuxi, Bonaccio, Marialaura, Gianfagna, Francesco, Signorelli, Carlo, Mosconi, Giansanto, Vigezzi, Giacomo Pietro, Rognoni, Magda, Paroni, Luca, Ciampichini, Roberta, Amerio, Andrea, Stival, Chiara, Lugo, Alessandra, Fanucchi, Tiziana, d'Oro, Luca Cavalieri, Iacoviello, Licia, Odone, Anna, Stuckler, David, Zucchi, Alberto, Serafini, Gianluca, and Gallus, Silvano

Published
2023
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4. Allocation of Users of Mental Health Services to Needs-Based Care Clusters: An Italian Pilot Study

Author

Barbato, Angelo, primary, D’Avanzo, Barbara, additional, Corrao, Giovanni, additional, Di Fiandra, Teresa, additional, Ferrara, Lucia, additional, Gaddini, Andrea, additional, Jarach, Carlotta Micaela, additional, Monzio Compagnoni, Matteo, additional, Saponaro, Alessio, additional, Scondotto, Salvatore, additional, Tozzi, Valeria D, additional, and Lora, Antonio, additional

Published
2023
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7. Allocation of Users of Mental Health Services to Needs-Based Care Clusters: An Italian Pilot Study

Author

Barbato, A, D'Avanzo, B, Corrao, G, Di Fiandra, T, Ferrara, L, Gaddini, A, Jarach, C, Monzio Compagnoni, M, Saponaro, A, Scondotto, S, Tozzi, V, Lora, A, Barbato, Angelo, D'Avanzo, Barbara, Corrao, Giovanni, Di Fiandra, Teresa, Ferrara, Lucia, Gaddini, Andrea, Jarach, Carlotta Micaela, Monzio Compagnoni, Matteo, Saponaro, Alessio, Scondotto, Salvatore, Tozzi, Valeria D, Lora, Antonio, Barbato, A, D'Avanzo, B, Corrao, G, Di Fiandra, T, Ferrara, L, Gaddini, A, Jarach, C, Monzio Compagnoni, M, Saponaro, A, Scondotto, S, Tozzi, V, Lora, A, Barbato, Angelo, D'Avanzo, Barbara, Corrao, Giovanni, Di Fiandra, Teresa, Ferrara, Lucia, Gaddini, Andrea, Jarach, Carlotta Micaela, Monzio Compagnoni, Matteo, Saponaro, Alessio, Scondotto, Salvatore, Tozzi, Valeria D, and Lora, Antonio

Abstract

In Italy, despite strong community-based mental health services, needs assessment is unsatisfactory. Using the Mental Health Clustering Tool (MHCT) we adopted a multidimensional and non-diagnosis dependent approach to assign mental health services users with similar needs to groups corresponding to resources required for effective care. We tested the MHCT in nine Departments of Mental Health in four Italian regions. After a brief training, 318 professionals assessed 12,938 cases with a diagnosis of schizophrenia, depression, bipolar disorder and personality disorder through the MHCT. 53% of cases were 40–59 years, half were females, 51% had a diagnosis of schizophrenia, 48% of cases were clinically severe. Clusters included different levels of clinical severity and diagnostic groups. The largest cluster was 11 (ongoing recurrent psychosis), with 18.9% of the sample, followed by cluster 3 (non-psychotic disorders of moderate severity). The MHCT could capture a variety of problems of people with mental disorders beyond the traditional psychiatric assessment, therefore depicting service population from a different standpoint. Following a brief training, MHCT assessment proved to be feasible. The automatic allocation of cases made the attribution to clusters easy and acceptable by professionals. To what extent clustering provide a sound base for care planning will be the matter of further research.

Published
2023

8. The role of smoking in COVID-19 progression: a comprehensive meta-analysis

Author

Gallus, Silvano, primary, Scala, Marco, additional, Possenti, Irene, additional, Jarach, Carlotta Micaela, additional, Clancy, Luke, additional, Fernandez, Esteve, additional, Gorini, Giuseppe, additional, Carreras, Giulia, additional, Malevolti, Maria Chiara, additional, Commar, Alison, additional, Fayokun, Ranti, additional, Gouda, Hebe N., additional, Prasad, Vinayak M., additional, and Lugo, Alessandra, additional

Published
2023
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9. COVID-19 pandemic impact on mental health in a large representative sample of older adults from the Lombardy region, Italy

Author

Amerio, Andrea, primary, Stival, Chiara, additional, Lugo, Alessandra, additional, Fanucchi, Tiziana, additional, d'Oro, Luca Cavalieri, additional, Iacoviello, Licia, additional, Odone, Anna, additional, Stuckler, David, additional, Zucchi, Alberto, additional, Serafini, Gianluca, additional, Gallus, Silvano, additional, Bosetti, Cristina, additional, Jarach, Carlotta Micaela, additional, Santucci, Claudia, additional, Amore, Mario, additional, De Sena, Roberto, additional, Ghislandi, Simone, additional, Wang, Yuxi, additional, Bonaccio, Marialaura, additional, Gianfagna, Francesco, additional, Signorelli, Carlo, additional, Mosconi, Giansanto, additional, Vigezzi, Giacomo Pietro, additional, Rognoni, Magda, additional, Paroni, Luca, additional, and Ciampichini, Roberta, additional

Published
2023
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12. The Statistical Analysis Plan for the Unification of Treatments and Interventions for Tinnitus Patients Randomized Clinical Trial (UNITI-RCT)

Author

Simoes, Jorge, primary, Schoisswohl, Stefan, additional, Schlee, Winfried, additional, Basso, Laura, additional, Bernal-Robledano, Alberto, additional, Boecking, Benjamin, additional, Cima, Rilana, additional, Denys, Sam, additional, Engelke, Milena, additional, Escalera-Balsera, Alba, additional, Gallego-Martinez, Alvaro, additional, Gallus, Silvano, additional, Kikidis, Dimitris, additional, Escámez, Jose Antonio López, additional, Marcrum, Steven C., additional, Markatos, Nikolaos, additional, Martin-Lagos, Juan, additional, Martinez-Martinez, Marta, additional, Mazurek, Birgit, additional, Vassou, Evgenia, additional, Jarach, Carlotta Micaela, additional, Mueller-Locatelli, Nicolas, additional, Neff, Patrick, additional, Niemann, Uli, additional, Omar, Hafez Kader, additional, Puga, Clara, additional, Schleicher, Miro, additional, Unnikrishnan, Vishnu, additional, Perez-Carpena, Patricia, additional, Pryss, Rüdiger, additional, Robles-Bolivar, Paula, additional, Rose, Matthias, additional, Schecklmann, Martin, additional, Schiele, Tabea, additional, Schobel, Johannes, additional, Spiliopoulou, Myra, additional, Stark, Sabine, additional, Vogel, Carsten, additional, Wunder, Nina, additional, Zachou, Zoi, additional, and Langguth, Berthold, additional

Published
2023
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13. Inclusion of Older Adults in Digital Health Technologies to Support Hospital-to-Home Transitions: Secondary Analysis of a Rapid Review and Equity-Informed Recommendations

Author

Kokorelias, Kristina Marie, primary, Nelson, Michelle LA, additional, Tang, Terence, additional, Steele Gray, Carolyn, additional, Ellen, Moriah, additional, Plett, Donna, additional, Jarach, Carlotta Micaela, additional, Xin Nie, Jason, additional, Thavorn, Kednapa, additional, and Singh, Hardeep, additional

Published
2022
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14. A real world analysis of COVID-19 impact on hospitalizations in older adults with chronic conditions from an Italian region

Author

Bosetti, Cristina, Rognoni, Magda, Ciampichini, Roberta, Paroni, Luca, Scala, Marco, D'Oro, Luca Cavalieri, Zucchi, Alberto, Amerio, Andrea, Iacoviello, Licia, Ghislandi, Simone, Odone, Anna, Stuckler, David, Gallus, Silvano, Jarach, Carlotta Micaela, Lugo, Alessandra, Stival, Chiara, Amore, Mario, Serafini, Gianluca, De Sena, Roberto, Wang, Yuxi, Bonaccio, Marialaura, Gianfagna, Francesco, Mosconi, Giansanto, Signorelli, Carlo, and Vigezzi, Giacomo

Subjects
ITALY, Multidisciplinary, Aged, Chronic Disease, Databases, Factual, Delivery of Health Care, Hospitalization, Humans, COVID-19, CHRONIC DISEASES, Databases, COVID-19, HOSPITALIZATIONS, CHRONIC DISEASES, ITALY, HOSPITALIZATIONS, Factual
Abstract

Healthcare delivery reorganization during the COVID-19 emergency may have had a significant impact on access to care for older adults with chronic conditions. We investigated such impact among all adults with chronic conditions aged ≥ 65 years, identified through the electronic health databases of two local health agencies—ATS Brianza and ATS Bergamo—from the Lombardy region, Italy. We considered hospitalizations for 2020 compared to the average 2017–2019 and quantified differences using rate ratios (RRs). Overall, in 2017–2019 there were a mean of 374,855 older adults with ≥ 1 chronic condition per year in the two ATS and 405,371 in 2020. Hospitalizations significantly decreased from 84,624 (225.8/1000) in 2017–2019 to 78,345 (193.3/1000) in 2020 (RR 0.86). Declines were reported in individuals with many chronic conditions and for most Major Diagnostic Categories, except for diseases of the respiratory system. The strongest reductions were observed in hospitalizations for individuals with active tumours, particularly for surgical ones. Hospitalization rates increased in individuals with diabetes, likely due to COVID-19-related diseases. Although determinants of the decrease in demand and supply for care among chronic older adults are to be further explored, this raises awareness on their impacts on chronic patients’ health in the medium and long run.

Published
2022

15. Who is Included in Digital Health Technologies to Support Hospital to Home Transitions for Older Adults?: Secondary analysis of a rapid review and equity-informed recommendations (Preprint)

Author

Kokorelias, Kristina Marie, primary, Nelson, Michelle LA, additional, Tang, Terence, additional, Steele Gray, Carolyn, additional, Ellen, Moriah, additional, Plett, Donna, additional, Jarach, Carlotta Micaela, additional, Xin Nie, Jason, additional, Thavorn, Kednapa, additional, and Singh, Hardeep, additional

Published
2021
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16. How digital health solutions align with the roles and functions that support hospital to home transitions for older adults: a rapid review study protocol

Author

Singh, Hardeep, primary, Armas, Alana, additional, Law, Susan, additional, Tang, Terence, additional, Steele Gray, Carolyn, additional, Cunningham, Heather V, additional, Thombs, Rachel, additional, Ellen, Moriah, additional, Sritharan, Jasvinei, additional, Nie, Jason X, additional, Plett, Donna, additional, Jarach, Carlotta Micaela, additional, Thavorn, Kednapa, additional, and Nelson, Michelle L A, additional

Published
2021
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18. The Impact of COVID-19 Confinement on Tinnitus and Hearing Loss in Older Adults: Data From the LOST in Lombardia Study.

Author

Jarach, Carlotta Micaela, Lugo, Alessandra, Stival, Chiara, Bosetti, Cristina, Amerio, Andrea, Cavalieri d'Oro, Luca, Iacoviello, Licia, Odone, Anna, Stuckler, David, Zucchi, Alberto, van den Brandt, Piet, Garavello, Werner, Cederroth, Christopher R., Schlee, Winfried, Gallus, Silvano, Serafini, Gianluca, Amore, Mario, Sena, Roberto De, Ghislandi, Simone, and Wang, Yuxi

Subjects
TINNITUS, HEARING disorders, OLDER people, COVID-19, SARS-CoV-2, POPULATION aging
Abstract

Background: Although a direct relationship between tinnitus or hearing difficulties and COVID-19 has been suggested, current literature provides inconsistent results, and no research has been undertaken in older adults. Methods: In November 2020, we conducted the LOST in Lombardia survey, a telephone-based cross-sectional study on a sample of 4,400 individuals representative of the general population aged ≥65 years from Lombardy region, Northern Italy. Individuals with diagnosed tinnitus and/or hearing loss were asked whether their conditions had improved or deteriorated in 2020 compared to 2019. Results: Overall, 8.1% of older adults reported a diagnosis of tinnitus and 10.5% of hearing loss. In 2020 compared to 2019, among individuals with tinnitus, those with increasing severity (5.0%) were similar to those decreasing it (5.3%). Among individuals with hearing loss, more people reported an increase (13.6%) than a decrease (3.2%) in their disease severity. No individual with a diagnosis in 2020 of tinnitus (n = 6) or hearing loss (n = 13) had COVID-19. The incidence of tinnitus was lower in 2020 (rate: 14.8 per 10,000 person-years) than in previous years (rate in 1990–2019: 36.0 per 10,000 person-years; p = 0.026). There was no change in the incidence of hearing loss (p = 0.134). Conclusions: In this large representative sample of older adults, on average neither COVID-19 confinement nor SARS-CoV-2 infection appeared to increase the severity or incidence of tinnitus. The increased severity of hearing difficulties may totally or partially be explained by physiologic deterioration of the condition, or by a misperception due to the use of face-masks. [ABSTRACT FROM AUTHOR]

Published
2022
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19. Social isolation and loneliness as related to progression and reversion of frailty in the Survey of Health Aging Retirement in Europe (SHARE).

Author

Jarach, Carlotta Micaela, Tettamanti, Mauro, Nobili, Alessandro, and D'avanzo, Barbara

Subjects
*FRAIL elderly, *LONELINESS, *RETIREMENT, *RISK assessment, *SOCIAL isolation, *DISEASE progression, *OLD age
Abstract

Background Frailty was shown to be associated with psychosocial risk factors, but there are few longitudinal data. Methods We used data from waves 5 and 6 of the Survey of Health Aging Retirement in Europe (SHARE) to study the contribution of loneliness and social isolation to transitions towards frailty defined according to Fried criteria in a sample of 27,468 individuals aged ≥60. Results At baseline, there were 13,069 (47.6%) robust individuals, 11,430 (41.6%) pre-frail and 2,969 (10.8%) frail. After 2 years, among robust subjects at baseline, 8,706 (61.8%) were still robust, 4,033 (30.8%) were pre-frail and 330 (2.6%) were frail. Among those who were pre-frail, 1,504 (13.2%) progressed to frail and 3,557 (31.1%) became robust. Among frail people, 182 (6.1%) reversed to robust and 1,271 (42.8%) to pre-frail. Average and high levels of loneliness and social isolation were significantly associated with the risk of robust people becoming frail and pre-frail (except robust with high loneliness to become frail), and of pre-frail people to become frail (except with average loneliness). Reversion to robustness was inversely associated with high levels of loneliness. Conclusion Average levels of loneliness and social isolation should not be considered acceptable and should be actively addressed even in the absence of any health conditions through an available evidence-based intervention. [ABSTRACT FROM AUTHOR]

Published
2021
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20. From HIV control to HIV elimination in Switzerland

Author

Tinike Haakma, Luder, Simone, Mueller, Eliane, Somaini, Bertino, Anaid Zulima Barreto Solano, Kleona Bezani, Rillion Cadlini, Cestonato, Sonja, Gil, Isabel, Ilic, Anica, Jarach, Carlotta Micaela, Pedercini, Violante, Tettamanti, Chiara, Torelli, Federica, Szczypkowski, Alexandre, and Leoni, Ester

Published
2016
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