352 results on '"Jaouen, Gerard"'
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2. Multifaceted chemical behaviour of metallocene (M = Fe, Os) quinone methides. Their contribution to biology
3. Synthesis and biodistribution of 1-[2-(cyclopentadienyltricarbonyltechnetium-99m)-2-oxo-ethoxy-phenyl]-1,2-di- (p-hydroxyphenyl)but-1-ene for tumor imaging
4. New mechanistic insights into osmium-based tamoxifen derivatives
5. Selective cytotoxicity of arene tricarbonylchromium towards tumour cell lines
6. Efficient ferrocifen anticancer drug and Bcl-2 gene therapy using lipid nanocapsules on human melanoma xenograft in mouse
7. The inhibition of tyrosinase by some aryl butenes: A desired activity or a side effect to avoid
8. Approach to ferrocenyl-podophyllotoxin analogs and their evaluation as anti-tumor agents
9. Synthesis and antiproliferative evaluation of novel hydroxypropyl-ferrociphenol derivatives, resulting from the modification of hydroxyl groups
10. Bioorganometallic chemistry: Structural diversity of organmetallic complexes with bioligands, and molecular recognition studies of several supramolecular hosts with biomolecules and alkali metal ions, including a potential organometallic breast cancer drug with estrogen receptor site proteins
11. Enzymatic oxidation of ansa-ferrocifen leads to strong and selective thioredoxin reductase inhibition in vitro
12. Osmocenyl-tamoxifen derivatives target the thioredoxin system leading to a redox imbalance in Jurkat cells
13. Ferrocene Functionalized Endocrine Modulators as Anticancer Agents
14. Arsenic-Based Drugs: From Fowler’s Solution to Modern Anticancer Chemotherapy
15. Physicochemical Characterization of Ferrocifen Lipid Nanocapsules: Customized Drug Delivery Systems Guided by the Molecular Structure
16. Ferrocifen derivatives that induce senescence in cancer cells: selected examples
17. Inhibition of ectopic glioma tumor growth by a potent ferrocenyl drug loaded into stealth lipid nanocapsules
18. Antibacterial properties and mode of action of new triaryl butene citrate compounds
19. Synthesis and characterization of new ferrocenyl compounds with different alkyl chain lengths and functional groups to target breast cancer cells
20. Ferrocifen stealth LNCs and conventional chemotherapy: A promising combination against multidrug-resistant ovarian adenocarcinoma
21. The effect of protic electron donor aromatic substituents on ferrocenic and [3]ferrocenophanic anilines and anilides: Some aspects of structure–activity relationship studies on organometallic compounds with strong antiproliferative effects
22. The in vivo performance of ferrocenyl tamoxifen lipid nanocapsules in xenografted triple negative breast cancer
23. Surface grafting of a π-conjugated amino-ferrocifen drug
24. Ferrocenyl flavonoid-induced morphological modifications of endothelial cells and cytotoxicity against B16 murine melanoma cells
25. Synthesis and antiproliferative evaluation of ferrocenyl and cymantrenyl triaryl butene on breast cancer cells. Biodistribution study of the corresponding technetium-99m tamoxifen conjugate
26. A new bioorthogonal cross-linker with alkyne and hydrazide end groups for chemoselective ligation. Application to antibody labelling
27. Biological evaluation of twenty-eight ferrocenyl tetrasubstituted olefins: Cancer cell growth inhibition, ROS production and hemolytic activity
28. Synthesis and biological activity of ferrocenyl derivatives of the non-steroidal antiandrogens flutamide and bicalutamide
29. Evaluation of bactericidal and fungicidal activity of ferrocenyl or phenyl derivatives in the diphenyl butene series
30. A ferrocenyl derivative of hydroxytamoxifen elicits an estrogen receptor-independent mechanism of action in breast cancer cell lines
31. Site-specific conjugation of metal carbonyl dendrimer to antibody and its use as detection reagent in immunoassay
32. Further insights into hydrophobic interactions between ferrocenyl-tamoxifen drugs and non-polar molecular architectures at electrode surfaces
33. Synthesis of N-functionalized 2,2′-dipyridylamine ligands, complexation to ruthenium (II) and anchoring of complexes to papain from papaya latex
34. The replacement of a phenol group by an aniline or acetanilide group enhances the cytotoxicity of 2-ferrocenyl-1,1-diphenyl-but-l-ene compounds against breast cancer cells
35. Antiproliferative effect of ferrocifen drug candidates on malignant pleural mesothelioma cell lines
36. Optimization of cisplatin for the treatment of hormone dependent tumoral diseases: Part 1: Use of steroidal ligands
37. Optimization of cisplatin for the treatment of hormone-dependent tumoral diseases: Part 2: Use of non-steroidal ligands
38. Treatment of 9L Gliosarcoma in Rats by Ferrociphenol-Loaded Lipid Nanocapsules Based on a Passive Targeting Strategy via the EPR Effect
39. Electrochemical attachment of a conjugated amino–ferrocifen complex onto carbon and metal surfaces
40. Lipid nanocapsules loaded with an organometallic tamoxifen derivative as a novel drug-carrier system for experimental malignant gliomas
41. Ferrocenyl compounds possessing protected phenol and thiophenol groups: Synthesis, X-ray structure, and in vitro biological effects against breast cancer
42. Formulation of ferrocifen loaded lipid nanocapsules against multidrug resistant ovarian adenocarcinoma
43. Organometallic diphenols: The importance of the organometallic moiety on the expression of a cytotoxic effect on breast cancer cells
44. Organometallic cluster analogues of tamoxifen: Synthesis and biochemical assay
45. Organometallic Complexes of Isomeric Acyl Isocyanides: Chromium Carbonyl (Acyl Isocyanide) and (Acyl Cyanide) Complexes
46. Labelling of biologically active molecules with a cyclohexadiene tricarbonyl iron unit
47. Selective functionalization of crown ethers via arene chromium tricarbonyl complexes
48. FACS analysis of oxidative stress induced on tumour cells by SERMs
49. Are the 11-oxo-steroids really so hindered towards organometallic compounds?
50. Introduction of a planar chirality onto steroid substrates: synthesis of ( S) and ( R)-2′-formylcymantrenyl-17α-ethynylestradiols using ( S) and ( R)-1-formyl-2-iodo-cymantrenes
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