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15 results on '"Jantzi C"'

1. Quasielastic $\overrightarrow{^{3}\mathrm{He}}(\overrightarrow{e},{e'})$ Asymmetry in the Threshold Region

Author: Nycz, M., Armstrong, W., Averett, T., Gayoso, C. Ayerbe, Bai, X., Bane, J., Barcus, S., Benesch, J., Bhatt, H., Bhetuwal, D., Biswas, D., Camsonne, A., Cates, G., Chen, J-P., Chen, J., Chen, M., Cotton, C., Dalton, M-M., Deltuva, A., Deur, A., Dhital, B., Duran, B., Dusa, S. C., Fernando, I., Fuchey, E., Gamage, B., Gao, H., Gaskell, D., Gautam, T., Gauthier, N., Golak, J., Hansen, J. -O., Hauenstein, F., Henry, W., Higinbotham, D. W., Huber, G., Jantzi, C., Jia, S., Jin, K., Jones, M., Joosten, S., Karki, A., Karki, B., Katugampola, S., Kay, S., Keppel, C., King, E., King, P., Korsch, W., Kumar, V., Li, R., Li, S., Li, W., Mack, D., Malace, S., Markowitz, P., Matter, J., McCaughan, M., Meziani, Z-E., Michaels, R., Mkrtchyan, A., Mkrtchyan, H., Morean, C., Nelyubin, V., Niculescu, G., Niculescu, M., Peng, C., Premathilake, S., Puckett, A., Rathnayake, A., Rehfuss, M., Reimer, P., Riley, G., Roblin, Y., Roche, J., Roy, M., Sauer, P. U., Scopeta, S., Satnik, M., Sawatzky, B., Seeds, S., Širca, S. S., Skibiński, R., Smith, G., Sparveris, N., Szumila-Vance, H., Tadepalli, A., Tadevosyan, V., Tian, Y., Usman, A., Voskanyan, H., Witala, H., Wood, S., Yale, B., Yero, C., Yoon, A., Zhang, J., Zhao, Z., Zheng, X., and Zhou, J.
Subjects: Nuclear Experiment
Abstract: A measurement of the double-spin asymmetry from electron-$^{3}$He scattering in the threshold region of two- and three-body breakup of $^{3}$He was performed at Jefferson Lab, for Q$^{2}$ values of 0.1 and 0.2 (GeV/$c$)$^{2}$. The results of this measurement serve as a stringent test of our understanding of few-body systems. When compared with calculations from plane wave impulse approximation and Faddeev theory, we found that the Faddeev calculations, which use modern nuclear potentials and prescriptions for meson-exchange currents, demonstrate an overall good agreement with data.
Published: 2024

2. Precision Determination of the Neutral Weak Form Factor of $^{48}$Ca

Author: Adhikari, D., Albataineh, H., Androic, D., Aniol, K. A., Armstrong, D. S., Averett, T., Gayoso, C. Ayerbe, Barcus, S. K., Bellini, V., Beminiwattha, R. S., Benesch, J. F., Bhatt, H., Pathak, D. Bhatta, Bhetuwal, D., Blaikie, B., Boyd, J., Campagna, Q., Camsonne, A., Cates, G. D., Chen, Y., Clarke, C., Cornejo, J. C., Dusa, S. Covrig, Dalton, M. M., Datta, P., Deshpande, A., Dutta, D., Feldman, C., Fuchey, E., Gal, C., Gaskell, D., Gautam, T., Gericke, M., Ghosh, C., Halilovic, I., Hansen, J. -O., Hassan, O., Hauenstein, F., Henry, W., Horowitz, C. J., Jantzi, C., Jian, S., Johnston, S., Jones, D. C., Kakkar, S., Katugampola, S., Keppel, C., King, P. M., King, D. E., Kumar, K. S., Kutz, T., Lashley-Colthirst, N., Leverick, G., Liu, H., Liyanage, N., Mammei, J., Mammei, R., McCaughan, 23 M., McNulty, D., Meekins, D., Metts, C., Michaels, R., Mihovilovic, M., Mondal, M. M., Napolitano, J., Narayan, A., Nikolaev, D., Owen, V., Palatchi, C., Pan, J., Pandey, B., Park, S., Paschke, K. D., Petrusky, M., Pitt, M. L., Premathilake, S., Quinn, B., Radloff, R., Rahman, S., Rashad, M. N. H., Rathnayake, A., Reed, B. T., Reimer, P. E., Richards, R., Riordan, S., Roblin, Y. R., Seeds, S., Shahinyan, A., Souder, P., Thiel, M., Tian, Y., Urciuoli, G. M., Wertz, E. W., Wojtsekhowski, B., Yale, B., Ye, T., Yoon, A., Xiong, W., Zec, A., Zhang, W., Zhang, J., and Zheng, X.
Subjects: Nuclear Experiment, Nuclear Theory
Abstract: We report a precise measurement of the parity-violating asymmetry $A_{\rm PV}$ in the elastic scattering of longitudinally polarized electrons from $^{48}{\rm Ca}$. We measure $A_{\rm PV} =2668\pm 106\ {\rm (stat)}\pm 40\ {\rm (syst)}$ parts per billion, leading to an extraction of the neutral weak form factor $F_{\rm W} (q=0.8733$ fm$^{-1}) = 0.1304 \pm 0.0052 \ {\rm (stat)}\pm 0.0020\ {\rm (syst)}$ and the charge minus the weak form factor $F_{\rm ch} - F_{\rm W} = 0.0277\pm 0.0055$. The resulting neutron skin thickness $R_n-R_p=0.121 \pm 0.026\ {\rm (exp)} \pm 0.024\ {\rm (model)}$~fm is relatively thin yet consistent with many model calculations. The combined CREX and PREX results will have implications for future energy density functional calculations and on the density dependence of the symmetry energy of nuclear matter., Comment: 8 pages, 5 figures Replace 6-16-22: included ancillary files, corrected errors in references, author affiliations. Small text changes for clarity
Published: 2022
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3. New Measurements of the Beam-Normal Single Spin Asymmetry in Elastic Electron Scattering Over a Range of Spin-0 Nuclei

Author: PREX, Collaborations, CREX, Adhikari, D., Albataineh, H., Androic, D., Aniol, K., Armstrong, D. S., Averett, T., Gayoso, C. Ayerbe, Barcus, S., Bellini, V., Beminiwattha, R. S., Benesch, J. F., Bhatt, H., Pathak, D. Bhatta, Bhetuwal, D., Blaikie, B., Boyd, J., Campagna, Q., Camsonne, A., Cates, G. D., Chen, Y., Clarke, C., Cornejo, J. C., Dusa, S. Covrig, Dalton, M. M., Datta, P., Deshpande, A., Dutta, D., Feldman, C., Fuchey, E., Gal, C., Gaskell, D., Gautam, T., Gericke, M., Ghosh, C., Halilovic, I., Hansen, J. -O., Hauenstein, F., Henry, W., Horowitz, C. J., Jantzi, C., Jian, S., Johnston, S., Jones, D. C., Karki, B., Kakkar, S., Katugampola, S., Keppel, C. E., King, P. M., King, D. E., Knauss, M., Kumar, K. S., Kutz, T., Lashley-Colthirst, N., Leverick, G., Liu, H., Liyange, N., Malace, S., Mammei, J., Mammei, R., McCaughan, M., McNulty, D., Meekins, D., Metts, C., Michaels, R., Mihovilovic, M., Mondal, M. M., Napolitano, J., Nikolaev, D., Rashad, M. N. H., Owen, V., Palatchi, C., Pan, J., Pandey, B., Park, S., Paschke, K. D., Petrusky, M., Pitt, M. L., Premathilake, S., Puckett, A. J. R., Quinn, B., Radloff, R., Rahman, S., Rathnayake, A., Reed, B. T., Reimer, P. E., Richards, R., Riordan, S., Roblin, Y., Seeds, S., Shahinyan, A., Souder, P. A., Tang, L., Thiel, M., Tian, Y., Urciuoli, G. M., Wertz, E. W., Wojtsekhowski, B., Xiong, W., Yale, B., Ye, T., Zec, A., Zhang, W., Zhang, J., and Zheng, X.
Subjects: Nuclear Experiment
Abstract: We report precision determinations of the beam normal single spin asymmetries ($A_n$) in the elastic scattering of 0.95 and 2.18~GeV electrons off $^{12}$C, $^{40}$Ca, $^{48}$Ca, and $^{208}$Pb at very forward angles where the most detailed theoretical calculations have been performed. The first measurements of $A_n$ for $^{40}$Ca and $^{48}$Ca are found to be similar to that of $^{12}$C, consistent with expectations thus demonstrating the validity of theoretical calculations for nuclei with Z~$\leq20$. We also report $A_n$ for $^{208}$Pb at two new momentum transfers (Q$^2$) extending the previous measurement. Our new data confirm the surprising result previously reported, with all three data points showing significant disagreement with the results from the $Z\leq 20$ nuclei. These data confirm our basic understanding of the underlying dynamics that govern $A_n$ for nuclei containing $\lesssim 50$ nucleons, but point to the need for further investigation to understand the unusual $A_n$ behaviour discovered for scattering off $^{208}$Pb., Comment: 7 pages, 2 figures
Published: 2021
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4. Accurate Determination of the Neutron Skin Thickness of $^{208}$Pb through Parity-Violation in Electron Scattering

Author: Adhikari, D., Albataineh, H., Androic, D., Aniol, K., Armstrong, D. S., Averett, T., Barcus, S., Bellini, V., Beminiwattha, R. S., Benesch, J. F., Bhatt, H., Pathak, D. Bhatta, Bhetuwal, D., Blaikie, B., Campagna, Q., Camsonne, A., Cates, G. D., Chen, Y., Clarke, C., Cornejo, J. C., Dusa, S. Covrig, Datta, P., Deshpande, A., Dutta, D., Feldman, C., Fuchey, E., Gal, C., Gaskell, D., Gautam, T., Gayoso, C. Ayerbe, Gericke, M., Ghosh, C., Halilovic, I., Hansen, J. -O., Hauenstein, F., Henry, W., Horowitz, C. J., Jantzi, C., Jian, S., Johnston, S., Jones, D. C., Karki, B., Katugampola, S., Keppel, C., King, P. M., King, D. E., Knauss, M., Kumar, K. S., Kutz, T., Lashley-Colthirst, N., Leverick, G., Liu, H., Liyange, N., Malace, S., Mammei, R., Mammei, J., McCaughan, M., McNulty, D., Meekins, D., Metts, C., Michaels, R., Mondal, M. M., Napolitano, J., Narayan, A., Nikolaev, D., Rashad, M. N. H., Owen, V., Palatchi, C., Pan, 14 J., Pandey, B., Park, S., Paschke, K. D., Petrusky, M., Pitt, M. L., Premathilake, S., Puckett, A. J. R., Quinn, B., Radloff, R., Rahman, S., Rathnayake, A., Reed, B. T., Reimer, P. E., Richards, R., Riordan, S., Roblin, Y., Seeds, S., Shahinyan, A., Souder, P., Tang, L., Thiel, 16 M., Tian, Y., Urciuoli, G. M., Wertz, E. W., Wojtsekhowski, B., Yale, B., Ye, T., Yoon, A., Zec, A., Zhang, W., Zhang, J., and Zheng, X.
Subjects: Nuclear Experiment
Abstract: We report a precision measurement of the parity-violating asymmetry $A_{PV}$ in the elastic scattering of longitudinally polarized electrons from $^{208}$Pb. We measure $A_{PV}=550\pm 16 {\rm (stat)}\pm 8\ {\rm (syst)}$ parts per billion, leading to an extraction of the neutral weak form factor $F_W(Q^2 = 0.00616\ {\rm GeV}^2) = 0.368 \pm 0.013$. Combined with our previous measurement, the extracted neutron skin thickness is $R_n-R_p=0.283 \pm 0.071$~fm. The result also yields the first significant direct measurement of the interior weak density of $^{208}$Pb: $\rho^0_W = -0.0796\pm0.0036\ {\rm (exp.)}\pm0.0013\ {\rm (theo.)}\ {\rm fm}^{-3}$ leading to the interior baryon density $\rho^0_b = 0.1480\pm0.0036\ {\rm (exp.)}\pm0.0013\ {\rm (theo.)}\ {\rm fm}^{-3}$. The measurement accurately constrains the density dependence of the symmetry energy of nuclear matter near saturation density, with implications for the size and composition of neutron stars.
Published: 2021
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5. New Measurements of the Beam-Normal Single Spin Asymmetry in Elastic Electron Scattering Over a Range of Spin-0 Nuclei

Author: PREX, Collaborations, CREX, Adhikari, D., Albataineh, H., Androic, D., Aniol, K., Armstrong, D. S., Averett, T., Gayoso, C. Ayerbe, Barcus, S., Bellini, V., Beminiwattha, R. S., Benesch, J. F., Bhatt, H., Pathak, D. Bhatta, Bhetuwal, D., Blaikie, B., Boyd, J., Campagna, Q., Camsonne, A., Cates, G. D., Chen, Y., Clarke, C., Cornejo, J. C., Dusa, S. Covrig, Dalton, M. M., Datta, P., Deshpande, A., Dutta, D., Feldman, C., Fuchey, E., Gal, C., Gaskell, D., Gautam, T., Gericke, M., Ghosh, C., Halilovic, I., Hansen, J. -O., Hauenstein, F., Henry, W., Horowitz, C. J., Jantzi, C., Jian, S., Johnston, S., Jones, D. C., Karki, B., Kakkar, S., Katugampola, S., Keppel, C. E., King, P. M., King, D. E., Knauss, M., Kumar, K. S., Kutz, T., Lashley-Colthirst, N., Leverick, G., Liu, H., Liyange, N., Malace, S., Mammei, J., Mammei, R., McCaughan, M., McNulty, D., Meekins, D., Metts, C., Michaels, R., Mihovilovic, M., Mondal, M. M., Napolitano, J., Nikolaev, D., Rashad, M. N. H., Owen, V., Palatchi, C., Pan, J., Pandey, B., Park, S., Paschke, K. D., Petrusky, M., Pitt, M. L., Premathilake, S., Puckett, A. J. R., Quinn, B., Radloff, R., Rahman, S., Rathnayake, A., Reed, B. T., Reimer, P. E., Richards, R., Riordan, S., Roblin, Y., Seeds, S., Shahinyan, A., Souder, P. A., Tang, L., Thiel, M., Tian, Y., Urciuoli, G. M., Wertz, E. W., Wojtsekhowski, B., Xiong, W., Yale, B., Ye, T., Zec, A., Zhang, W., Zhang, J., and Zheng, X.
Subjects: General Physics and Astronomy, FOS: Physical sciences, Nuclear Experiment (nucl-ex), single spin asymmetry, elastic electron scattering, Nuclear Experiment
Abstract: We report precision determinations of the beam normal single spin asymmetries ($A_n$) in the elastic scattering of 0.95 and 2.18~GeV electrons off $^{12}$C, $^{40}$Ca, $^{48}$Ca, and $^{208}$Pb at very forward angles where the most detailed theoretical calculations have been performed. The first measurements of $A_n$ for $^{40}$Ca and $^{48}$Ca are found to be similar to that of $^{12}$C, consistent with expectations thus demonstrating the validity of theoretical calculations for nuclei with Z~$\leq20$. We also report $A_n$ for $^{208}$Pb at two new momentum transfers (Q$^2$) extending the previous measurement. Our new data confirm the surprising result previously reported, with all three data points showing significant disagreement with the results from the $Z\leq 20$ nuclei. These data confirm our basic understanding of the underlying dynamics that govern $A_n$ for nuclei containing $\lesssim 50$ nucleons, but point to the need for further investigation to understand the unusual $A_n$ behaviour discovered for scattering off $^{208}$Pb., Comment: 7 pages, 2 figures
Published: 2022

6. Linagliptin Effects on Heart Failure and Related Outcomes in Individuals With Type 2 Diabetes Mellitus at High Cardiovascular and Renal Risk in CARMELINA

Author: McGuire D, Alexander J, Johansen O, Perkovic V, Rosenstock J, Cooper M, Wanner C, Kahn S, Toto R, Zinman B, Baanstra D, Pfarr E, Schnaidt S, Meinicke T, George J, von Eynatten M, Marx N, Aizenberg D, Fiorella A, Edgardo N, Belen C, Alonso P, Walter M, Maia K, Guillermo S, Leandro B, Constanza R, Alejandra N, Melina C, Ariel I, Rodrigo C, Alvarez C, Jorge M, Gabriel C, German S, Bartolacci I, Bolobanich G, Tale T, Meritano M, Echeverria M, Gerrini S, Alvarez M, Torrijos N, Berli M, Coggiola J, Castaneda G, Rode R, Milessi R, Roude A, Bono J, Caresani J, Arias V, Westberg J, Allende G, Liberman A, Bordonava A, Almagro S, Gerbaudo C, Schiavi L, Budassi N, Cecilia M, Buncuga M, Carlos S, Osvaldo T, Mercedes S, Calella P, Agustina V, Aljandro M, Alberto D, Fiorella M, Cantero M, Cariganano M, Anadon P, Cartasegna L, Gabriela M, Fernanda A, Alberto R, Chacon C, Jazmin F, Colombo H, Coni E, Mattausch S, Thomsenhall K, della Torre M, Morandini M, Berra F, Margarita H, Commendatore V, Tedesco J, Bolzan P, Cuneo C, Narcisa G, Caputi V, Pablo S, Sandra G, Pacora F, Tinari M, Jure H, Parody M, Toranzo A, Frechtel G, Yohena S, Lovecchio S, Muller C, Martin S, Olivera C, Breyaui M, Bianchi G, Garcia C, Luciana V, Florencia F, Ruben G, Gelersztein E, Rey G, Sanchez C, Fornasari L, Di Pierro L, Giacomi G, Miguel S, Laura T, Gonzalo C, Ramon C, Glenny J, Koretzky M, Porto A, Tiberio O, Ellenberg A, Saurral R, Igarzabal C, Vilamajo O, Matkovich J, de Lapertosa S, Villagra M, Cuzziol G, de la Cruz M, Pinchetti R, Mierez M, Lopez C, Gorosito V, Gabito A, Kleiban A, Grosembacher L, Adrian P, Paula R, Javier G, Kraft F, Andres F, Krynski F, Nicolas P, Marcelo F, Alfredo F, de la Fuente R, Natalia C, Luquez H, Recuero Y, Becchetti N, Ruiz M, Costantino M, Vazquez G, Guzman C, Pelatia P, Maffei L, Sassone S, Yantorno M, Prado G, Khron B, Maldonado N, Gustavo L, Veronica V, Marino J, Elizabeth A, Alejandra C, Oscar R, Azize G, Gallardo M, Escudero M, Vargas E, Ramos H, Lucero C, Najenson M, Crocci I, Chiesa A, Nardone L, Dominguez S, Zanini A, Manghi F, Grossman M, Giudice G, Romeo A, Piskorz D, Miguel C, Susana D, Noeli U, Rosa S, Martin V, Soledad A, Virginia M, Lorena G, Prado A, Veronica L, Eduardo H, Adolfo P, Florencia W, Rista L, Scolari C, Rojas N, Bertolio V, Zarandon R, Jair S, Orlando C, Sanabria H, Ignacio D, Viviana C, Marina R, Sarjanovich R, Scaro G, Huerta C, Mana M, Gutierrez M, Dain A, Gavicola R, Sessa H, Sacripanti J, Felman R, Vilarino P, Sicer M, Lagrutta M, Sala J, Casabella T, Cecilia H, Carlos B, Vines G, Javier R, Vico M, Lanchiotti P, Martella C, Torres L, Villarino A, Molina M, Martinez J, Farias C, Bertola S, Rojas M, Guzman P, Nisi J, Martinez D, Barrionuevo M, Vita N, Lopez A, Vottero E, Giuliano M, Paron L, Vogel D, Mele P, Imposti H, Dominguez A, Zaidman C, Fernando G, Beck M, Beltrame P, Chemello D, Junior R, Abreu A, Fernandes V, Saboia J, Rodrigues L, Carvalho M, Gurgel M, Gadelha D, Ramos C, Borba V, Golbert M, Pitthan M, Golbert L, Valentini R, Canani L, Gross J, Valenti A, Sartori C, Dutra O, Azevedo E, Azevedo A, Vaz R, Vaz H, da Costa F, da Costa L, Panarotto D, Lain F, Camazzola F, Dellomea B, Rech R, Pizzato P, Nunes C, Jaeger C, Silveira D, Wagner L, Machado L, Rea R, de Bem A, Alves J, Jonasson T, Malucelli F, Betti R, Lerario A, Lisboa H, Bem J, Tres G, Tavares C, Nardi A, Pozzatto M, Backes L, Reolao J, Scariot E, Ziguer E, Baldissera D, Griz L, Antunes D, Victor F, Freire K, Barros A, Costi B, Sa M, Carneiro A, Felicio J, Felicio K, Penha P, Ferreira J, Melo F, Alves A, Souza A, Costa L, Pinheiro D, Turatti L, Augusto G, Leanca C, Santomauro A, Forti A, Sena R, Marinho A, Facanha C, de Souza K, de Souza A, de Queiroz W, Leite S, Vieira S, Gubert L, Olsen A, Piazzetta G, Fuck A, Ferreira M, Fortes J, Brandao T, Alves F, Radice E, dos Santos J, de Almeida R, Franco D, Saporito W, Eliaschewitz F, de Siqueira K, Bona R, Genestreti P, de Castro D, Visconti G, Sampaio C, Palhares F, Konigsfeld H, Alves E, Feder C, Leao B, Saraiva J, Rodovalho S, Costa M, Pires N, Figueiredo E, Werner G, Garcia J, de Paiva I, Quirino B, Botelho R, da Silva R, Navarro A, Lourenco C, Pereira A, Arantes F, Boner D, Saad J, Falchetto E, Washizu E, Mandil A, Pimenta N, Tofani F, Fonseca T, Teixeira L, Maia L, Lemos M, Mouco O, Nakazone M, Weiand L, Bohn J, Hissa M, Araripe F, Carvalho F, Cancado G, Wang R, Chacra A, Fusaro A, de Mendonca E, Cercato C, Halpern A, Alves B, Braile M, Sestito R, Mustafa E, Ferreira V, Sbardellini B, de Almeida P, Guimaraes F, Piedade M, Bienert I, Braga J, Daher R, Hirakawa T, Terra E, Farias E, Figueiredo M, Lima L, Moraes K, Avelino I, Flato U, Plavnik F, Portes E, Moreira M, Vendramini M, Veloso R, Padilha M, Rodrigues A, Adam R, Santos S, Sayeg N, Guerrero D, Madeira M, Siqueira J, Pinheiro R, Villacorta A, Mellazi A, Braga T, Kaiser S, Paolino B, Lefterov I, Marinchev A, Angelova S, Klyuchkova N, Lybomirova Z, Kerekovski Y, Kuneva T, Penkova D, Levterov G, Videnova E, Georgieva P, Shinkov A, Borissova A, Vlahov J, Dakovska-Dekova L, Lucheva M, Luchev P, Temelkova M, Borisova K, Tsenov S, Andreeva V, Margaritov V, Arasheva G, Lozanov L, Borisov R, Gorcheva D, Henein S, Whatley S, Boutros M, Kalyniuk N, Berlingieri J, Nisker W, Hoag G, Hepburn D, Harvey M, Manjoo P, Yale J, Sherman M, Tsoukas M, Rehman W, Mason M, Santerre M, De Kock J, Barkhuizen F, Rooke C, Gill C, Kooy J, Burgoyne G, de Kock J, Degen G, Hockman L, Invik R, Roberts P, Ward K, Alasaad H, Susan A, Davies V, Gupta N, Milhalidis J, Grossman L, Agawal N, Yared Z, Rwaheed, Nouhad S, Nahla A, Khandwala H, Warwick A, Wadehra D, Manan A, Vecchiarelli J, Aslam N, Ferrao A, St-Maurice F, Collette R, Davey B, Nawaz S, Coutu B, Costi P, Greiss I, Mansour F, Raymond J, St-Phard W, Nadra I, Della Siega A, Barahona L, Klinke P, Contractor H, Fryer M, Chandra N, Conti B, Telzer L, Sorensen S, Lounsbury N, Martin E, Mitchell L, Pelzer E, Nelson S, Jones M, Cox J, Luco G, Trhoughton T, Labonte R, Chouinard G, Frechette A, Rheaume M, Cusson J, Faucher J, Dery V, Kelly A, Miranda B, Al-Kayssi N, Malette P, Rheault P, Fredette P, Dumas R, Palardy J, Belanger A, Boucher P, Doyon B, Charbonneau J, Bailey G, Odendaal M, Stephan K, Badenhorst J, Knight D, Thurgood A, Johnston M, Cooper-Rosen E, Jagger R, Green M, Weisnagel S, Gangloff A, Bergeron J, Pesant Y, Chevalier P, Woo V, Hurd C, Ruckert G, Lira J, Navarro G, Venegas M, Gonzalez P, Montecinos H, Vidal G, Fernandez M, Varas J, Fernandez C, Aguilar J, Marin R, Kindel C, Yovaniniz P, Gherman O, Aravena M, Carvajal J, Macias E, Corrado P, Lazcano M, Garrido B, Charme G, Carrasco J, Vignolo P, Saavedra S, Gajardo V, Saavedra C, Santamaria D, del Castillo B, Balda I, Zurvarra V, Fu G, Jiang D, Huang H, Wang M, Song J, Lu W, Lin Y, Lu Z, Shi Y, Zhong M, Zhao X, Chen D, Zhang G, He Y, Shi P, Chu K, Gao Q, Deng W, Zhang J, Zhang Y, Chen H, Liu E, Xie Y, Lin R, Tan W, Yuan Z, Wang Y, Ren J, Yu H, Luo M, Ma W, Shi W, Xu H, Xu M, Liu G, 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Ocicka-Kozakiewicz A, Jurowiecki J, Stasinska T, Karczewicz-Janowska J, Jaruga J, ZytkiewiczJaruga D, Krupinska E, Pupek-Musialik D, Bogdanski P, Szulinska M, Skrypnik D, Skokowska E, Bojarska-Los M, Giermkowska-Samek M, Pirog M, Wojnowski L, Jelinska A, Gradzka M, Danyluk A, Lysek R, Sliwinska T, Podrazka-Szczepaniak A, Barney M, Tomczyk A, Necki M, Malicka J, Dudzinska M, KiszczakBochynska E, Markiewicz A, Galbas K, Paciorkowski A, Mazur S, Mazur M, Chmielowski A, Swiatek A, Sobocka B, Wis J, Jozefowska M, Kaczmarek M, Timler M, Cieplucha Z, Lazuka L, Lazuka N, Wittek A, Spyra J, Jasiel-Wojculewicz H, Stefanski A, Wierucki L, Hanczuk A, Misiura M, Szmygel K, Kolcowa O, Orlowska-Kunikowska E, Rutkowski M, Ignaszewska-Wyrzykowska A, Popenda G, Maciejewska J, Mostowy A, WojteckaGrabka M, Grazyna M, Wieslaw K, Barbara K, Kramarczuk E, Wojciech C, Jaroslaw H, Ewa B, Karas P, Agnieszka S, Hanna C, Justyna S, Piotr K, Wozniak I, Mateusz W, Katarzyna W, Jacek F, Andrzej J, Cymerman K, Gmytrasiewicz M, Zambrzycki J, Krysiak-Kowaluk H, Klodawska K, Klszczewski Z, Zieleniewski J, Opadczuk P, Urbanska K, Faran-Grabowska K, Szczepanik T, Siegel A, Kleczek A, Kincel K, Nowak D, Slowik-Gomulka L, Watemborska-Matuszyk G, Lampart J, Strozik-Krecichwost A, Dziewit T, Broncel M, Wojcik-Odyniec J, Jakubczyk E, Wierzbicka K, Witowicz A, Jedrych B, Korczyk P, Socik-Pojawa M, Monteiro P, Monteiro S, Mendes P, Soares F, Mendes S, Leite L, Vicente J, Santos M, Ferreira A, Alves P, Rosario F, Garrao A, Duarte L, Rogado C, Duarte R, Laginha T, Matos P, Raposo J, Mariz J, Teixeira J, Capela C, Leitao A, Cardiga R, Alface M, Augusto S, Basto L, Cunha A, Rei D, Dantas J, Verdasca I, Andrade L, Silva A, Suarez M, Dias V, Silva J, Pereira N, Goncalves M, Goncalves A, Silveira A, Sampaio A, Dias A, Diogo M, Vilaca C, Cif A, Calin T, Elena S, Crisan C, Adina S, Ramona S, Anghel V, Simona C, Turcu L, Mihaela V, Cosma D, Cristina H, Marius-Calin H, Negrisanu G, Andreea-Andrada M, Maria-Mihaela 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Lama M, del Rio E, Zlova T, Ponomarenko K, Karpenko O, Bezuglova S, Mitskevych L, Kizim S, Nevolina I, Katerenchuk V, Liudmyla B, Ivan K, Rudyk I, Olena M, Anna I, Ganna B, Topchii I, Semenovykh P, Yulia Y, Mykhalchyshyn G, Kirienko D, Kobiliak N, Bodnar, Mykhalchyshyn, Pertseva N, Olena G, Tomashkevych H, Korpachev V, Prybyla O, Kovalchuk A, Kushnarova N, Zinych O, Tseluyko V, Andriy Z, Olga R, Mankovskyy B, Zherdova N, Lykhoshapko O, Logoida P, Godlevska O, Olena V, Olga C, Gyrina O, Alifer O, Dozhuk K, Pekhenko V, Gorobets N, Korneichuk A, Makarenko E, Martynyuk L, Martynuyk O, Stanislavchuk M, Larysa P, Natalia S, Botsyurko V, Kostitska I, Dzeman O, Ablitsov Y, Ivaseiko S, Konovart O, Sandurska S, Vendzilovych Y, Samoylov O, Iryna C, Rozhkivska L, Ulyanchenko I, Kateryna V, Orlenko V, Ivaskina K, Tronko M, Tronko K, Pashkovska N, Stankova N, Vynnychenko L, Bolotnikova N, Demokhova N, Reshotko D, Popova A, Dr Bogdana, Tetiana S, Svitlana D, Oksana R, Vlasenko M, Litvinova S, 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Colfer H, Kane L, Teklinski A, Gadowski G, Levanovich P, Saba F, Confident L, Hossain S, Steinberg B, Philippe B, Choroenthkongtrakal S, Boccalano F, Anand R, Syam V, Manohar A, Suresh P, Madhusudhan P, Patel P, Cambier P, Klonaris J, Cheng W, Fisher S, Schelle M, Reese L, McLean S, Poock J, Hoens J, Rosie A, Welshons R, Dean J, Kuhlman P, Luke R, Lohrbauer L, Cunningham M, Buday P, Lehmann M, Chrzanowski K, Fletcher A, Hargrove J, Harris F, Debs-Perez G, Maiquez A, Cordoves L, Georgescu M, Tayoun H, Munoz F, Ortiz D, Munoz G, Hamzeh I, Misra A, Zhang L, Forgosh L, Loria K, Roncari C, Hommerding J, Morris G, Lebron C, Blake K, LaVenture K, Lange C, Levinson L, Baungarten T, Edevante S, Shawley S, Moyer H, Elliott K, Iachini K, Rajan R, Davis C, Shattuck A, Simon W, Lakin G, Secrist N, Buth D, Steere D, Talbot K, Singh N, Mascolo R, Sloan S, Kmetzo J, Brown J, Carter L, Lawrence M, Arauz-Pacheco C, Lender D, Kozlow W, Cavanaugh L, Wilson J, Gujja P, Akhter F, Khan M, Mohammed A, Satyavolu S, Dev D, Yalamanchili H, Sumeyye C, Fernandes H, Chaleff F, Jancko M, Trenche S, Kaplan W, Wilcox S, Goisse M, Rua M, Black J, Chapman K, Suh D, Yan L, Song D, Chanara S, Houchin V, McKeinness A, Sotolongo R, Gutierrez K, Miranda-Palma B, Solano M, Jain M, Needell J, Banerjee A, Jarratt M, Hantel S, Lees K, Welty F, Freedman S, Parhofer K, Birkeland K, McGill J, Tijssen J, Clemmensen P, Pehrson S, Grande P, Januzzi J, Wood M, Petrie M, Sairanen T, Tatlisumak T, Soinne L, Kase C, Turan T, Mann J, Agarwal R, Fogarty D, Navaneethan S, Srinivas T, Forsmark C, Frossard J, Gelrud A, Mayerle J, Lee R, Heist R, Sullivan R, Buchbinder E, Chodak G, Edelman M, Thompson V, Coles A, and CARMELINA Investigators
Subjects: cardiovascular disease, type 2 diabetes mellitus, heart failure, chronic kidney diseases
Abstract: Background: Individuals with type 2 diabetes mellitus are at increased risk for heart failure (HF), particularly those with coexisting atherosclerotic cardiovascular disease and/or kidney disease. Some but not all dipeptidyl peptidase-4 inhibitors have been associated with increased HF risk. We performed secondary analyses of HF and related outcomes with the dipeptidyl peptidase-4 inhibitor linagliptin versus placebo in CARMELINA (The Cardiovascular and Renal Microvascular Outcome Study With Linagliptin), a cardiovascular outcomes trial that enrolled participants with type 2 diabetes mellitus and atherosclerotic cardiovascular disease and/or kidney disease. Methods: Participants in 27 countries with type 2 diabetes mellitus and concomitant atherosclerotic cardiovascular disease and/or kidney disease were randomized 1:1 to receive once daily oral linagliptin 5 mg or placebo, on top of standard of care. All hospitalization for HF (hHF), cardiovascular outcomes, and deaths were prospectively captured and centrally adjudicated. In prespecified and post hoc analyses of HF and related events, Cox proportional hazards models adjusting for region and baseline history of HF were used. Recurrent hHF events were analyzed using a negative binomial model. In a subset of participants with left ventricular ejection fraction captured within the year before randomization, HF-related outcomes were assessed in subgroups stratified by left ventricular ejection fraction > or 50%. Results: CARMELINA enrolled 6979 participants (mean age, 65.9 years; estimated glomerular filtration rate, mL/min per 1.73m(2); hemoglobin A1c, 8.0%; 62.9% men; diabetes mellitus duration, 14.8 years), including 1873 (26.8%) with a history of HF at baseline. Median follow-up was 2.2 years. Linagliptin versus placebo did not affect the incidence of hHF (209/3494 [6.0%] versus 226/3485 [6.5%], respectively; hazard ratio [HR], 0.90; 95% CI, 0.74-1.08), the composite of cardiovascular death/hHF (HR, 0.94; 95% CI, 0.82-1.08), or risk for recurrent hHF events (326 versus 359 events, respectively; rate ratio, 0.94; 95% CI, 0.75-1.20). There was no heterogeneity of linagliptin effects on hHF by history of HF at baseline, baseline estimated glomerular filtration rate or urine albumin-creatinine ratio, or prerandomization left ventricular ejection fraction. Conclusions: In a large, international cardiovascular outcome trial in participants with type 2 diabetes mellitus and concomitant atherosclerotic cardiovascular disease and/or kidney disease, linagliptin did not affect the risk of hHF or other selected HF-related outcomes, including among participants with and without a history of HF, across the spectrum of kidney disease, and independent of previous left ventricular ejection fraction. Clinical Trial Registration: URL: https://www.clinicaltrials.gov. Unique identifier: NCT01897532.
Published: 2019

7. Effect of Linagliptin vs Placebo on Major Cardiovascular Events in Adults With Type 2 Diabetes and High Cardiovascular and Renal Risk The CARMELINA Randomized Clinical Trial

Author: Rosenstock J, Perkovic V, Johansen O, Cooper M, Kahn S, Marx N, Alexander J, Pencina M, Toto R, Wanner C, Zinman B, Woerle H, Baanstra D, Pfarr E, Schnaidt S, Meinicke T, George J, von Eynatten M, McGuire D, Aizenberg D, Fiorella A, Edgardo N, Belen C, Alonso P, Walter M, Maia K, Guillermo S, Leandro B, Constanza R, Alejandra N, Melina C, Ariel I, Rodrigo C, Alvarez C, Jorge M, Gabriel C, German S, Bartolacci I, Bolobanich G, Tale T, Meritano M, Echeverria M, Gerrini S, Alvarez M, Torrijos N, Berli M, Coggiola J, Castaneda G, Rode R, Milessi R, Roude A, Bono J, Caresani J, Arias V, Westberg J, Allende G, Liberman A, Bordonava A, Almagro S, Gerbaudo C, Schiavi L, Budassi N, Cecilia M, Buncuga M, Carlos S, Osvaldo T, Mercedes S, Calella P, Agustina V, Aljandro M, Alberto D, Fiorella M, Cantero M, Cariganano M, Anadon P, Cartasegna L, Gabriela M, Fernanda A, Alberto R, Chacon C, Jazmin F, Colombo H, Coni E, Mattausch S, Thomsenhall K, della Torre M, Morandini M, Berra F, Margarita H, Commendatore V, Tedesco J, Bolzan P, Cuneo C, Narcisa G, Caputi V, Pablo S, Sandra G, Pacora F, Tinari M, Jure H, Parody M, Toranzo A, Frechtel G, Yohena S, Lovecchio S, Muller C, Martin S, Olivera C, Breyaui M, Bianchi G, Garcia C, Luciana V, Florencia F, Ruben G, Gelersztein E, Rey G, Sanchez C, Fornasari L, Di Pierro L, Giacomi G, Miguel S, Laura T, Gonzalo C, Ramon C, Glenny J, Koretzky M, Porto A, Tiberio O, Ellenberg A, Saurral R, Igarzabal C, Vilamajo O, Matkovich J, de Lapertosa S, Villagra M, Cuzziol G, de la Cruz M, Pinchetti R, Mierez M, Lopez C, Gorosito V, Gabito A, Kleiban A, Grosembacher L, Adrian P, Paula R, Javier G, Kraft F, Andres F, Krynski F, Nicolas P, Marcelo F, Alfredo F, de la Fuente R, Natalia C, Luquez H, Recuero Y, Becchetti N, Ruiz M, Costantino M, Vazquez G, Guzman C, Pelatia P, Maffei L, Sassone S, Yantorno M, Prado G, Khron B, Maldonado N, Gustavo L, Veronica V, Marino J, Elizabeth A, Alejandra C, Oscar R, Azize G, Gallardo M, Escudero M, Vargas E, 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Kirk U, Tatu H, Stamatin R, Lupea S, Frasie M, Colfer H, Kane L, Teklinski A, Gadowski G, Levanovich P, Saba F, Confident L, Hossain S, Steinberg B, Philippe B, Choroenthkongtrakal S, Boccalano F, Anand R, Syam V, Manohar A, Suresh P, Madhusudhan P, Patel P, Cambier P, Klonaris J, Cheng W, Fisher S, Schelle M, Reese L, McLean S, Poock J, Hoens J, Rosie A, Welshons R, Dean J, Kuhlman P, Luke R, Lohrbauer L, Cunningham M, Buday P, Lehmann M, Chrzanowski K, Fletcher A, Hargrove J, Harris F, Debs-Perez G, Maiquez A, Cordoves L, Georgescu M, Tayoun H, Munoz F, Ortiz D, Munoz G, Hamzeh I, Misra A, Zhang L, Forgosh L, Loria K, Roncari C, Hommerding J, Morris G, Lebron C, Blake K, LaVenture K, Lange C, Levinson L, Baungarten T, Edevante S, Shawley S, Moyer H, Elliott K, Iachini K, Rajan R, Davis C, Shattuck A, Simon W, Lakin G, Secrist N, Buth D, Steere D, Talbot K, Singh N, Mascolo R, Sloan S, Kmetzo J, Brown J, Carter L, Lawrence M, Arauz-Pacheco C, Lender D, Kozlow W, Cavanaugh L, Wilson J, Gujja P, Akhter F, Khan M, Mohammed A, Satyavolu S, Dev D, Yalamanchili H, Sumeyye C, Fernandes H, Chaleff F, Jancko M, Trenche S, Kaplan W, Wilcox S, Goisse M, Rua M, Black J, Chapman K, Suh D, Yan L, Song D, Chanara S, Houchin V, McKeinness A, Sotolongo R, Gutierrez K, Miranda-Palma B, Solano M, Jain M, Needell J, Banerjee A, Jarratt M, Hantel S, Lees K, Welty F, Freedman S, Parhofer K, Birkeland K, McGill J, Tijssen J, Clemmensen P, Pehrson S, Grande P, Januzzi J, Wood M, Petrie M, Sairanen T, Tatlisumak T, Soinne L, Kase C, Turan T, Mann J, Agarwal R, Fogarty D, Navaneethan S, Srinivas T, Forsmark C, Frossard J, Gelrud A, Mayerle J, Lee R, Heist R, Sullivan R, Buchbinder E, Chodak G, Edelman M, Thompson V, Coles A, and CARMELINA Investigators
Abstract: IMPORTANCE Type 2 diabetes is associated with increased cardiovascular (CV) risk. Prior trials have demonstrated CV safety of 3 dipeptidyl peptidase 4 (DPP-4) inhibitors but have included limited numbers of patients with high CV risk and chronic kidney disease. OBJECTIVE To evaluate the effect of linagliptin, a selective DPP-4 inhibitor, on CV outcomes and kidney outcomes in patients with type 2 diabetes at high risk of CV and kidney events. DESIGN, SETTING, AND PARTICIPANTS Randomized, placebo-controlled, multicenter noninferiority trial conducted from August 2013 to August 2016 at 605 clinic sites in 27 countries among adults with type 2 diabetes, hemoglobin A(1c) of 6.5% to 10.0%, high CV risk (history of vascular disease and urine-albumin creatinine ratio [UACR] > 200mg/g), and high renal risk (reduced eGFR and micro-or macroalbuminuria). Participants with end-stage renal disease (ESRD) were excluded. Final follow-up occurred on January 18, 2018. INTERVENTIONS Patients were randomized to receive linagliptin, 5 mg once daily (n = 3494), or placebo once daily (n = 3485) added to usual care. Other glucose-lowering medications or insulin could be added based on clinical need and local clinical guidelines. MAIN OUTCOMES AND MEASURES Primary outcomewas time to first occurrence of the composite of CV death, nonfatalmyocardial infarction, or nonfatal stroke. Criteria for noninferiority of linagliptin vs placebo was defined by the upper limit of the 2-sided 95% CI for the hazard ratio (HR) of linagliptin relative to placebo being less than 1.3. Secondary outcome was time to first occurrence of adjudicated death due to renal failure, ESRD, or sustained 40% or higher decrease in eGFR from baseline. RESULTS Of 6991 enrollees, 6979 (mean age, 65.9 years; eGFR, 54.6 mL/min/1.73m2; 80.1% with UACR > 30mg/g) received at least 1 dose of study medication and 98.7% completed the study. During a median follow-up of 2.2 years, the primary outcome occurred in 434 of 3494 (12.4%) and 420 of 3485 (12.1%) in the linagliptin and placebo groups, respectively, (absolute incidence rate difference, 0.13 [95% CI,-0.63 to 0.90] per 100 person-years) (HR, 1.02; 95% CI, 0.89-1.17; P
Published: 2019

8. Vocal frequency suppression apparatus and method

Author: Jantzi, C. Earl, primary
Published: 1996
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9. Efficacy and safety of dapagliflozin in patients with inadequately controlled type 1 diabetes (DEPICT-1): 24 week results from a multicentre, double-blind, phase 3, randomised controlled trial

Author: Paresh Dandona, Chantal Mathieu, Moshe Phillip, Lars Hansen, Steven C Griffen, Diethelm Tschöpe, Fredrik Thorén, John Xu, Anna Maria Langkilde, Joseph Proietto, Stephen Stranks, Roger Chen, David O'Neal, Alexia Pape, Mark Forbes, Claire Morbey, Anton Luger, Ursula Hanusch, Christoph Schnack, Evelyn Fliesser-Goerzer, Bertram Hoelzl, Christoph Ebenbichler, Rudolf Prager, Luc Van Gaal, Chris Vercammen, Andre Scheen, Francis Duyck, Frank Nobels, Johannes Ruige, Naresh Aggarwal, Vincent Woo, Bruno St-Pierre, Richard Dumas, Irene Hramiak, Thomas Elliott, Troels Krarup Hansen, Jan Erik Henriksen, Jeppe Gram, Aina Lihn, Jens Bruun, Juha Saltevo, Jyrki Taurio, Jorma Strand, Timo Valle, Sakari Nieminen, Kirsi Pietilainen, Bruno Guerci, Samy Hadjadj, Bertrand Cariou, Bruno Verges, Sophie Borot, Alfred Penfornis, Thomas Schaum, Diethelm Tschoepe, Cornelia Marck, Thomas Horacek, Ludger Rose, Gerhard Klausmann, Joerg Luedemann, Steffi Appelt, Ulrich Aigner, Rolf Goebel, Thomas Behnke, Anette-Gabriele Ziegler, Eva Peterfai, Zsuzsanna Kerenyi, Tamas Oroszlan, Gyula G. Kiss, Laszlo Konyves, Gyorgyi Piros, Ofri Mosenzon, Naim Shehadeh, Faiad Adawi, Julio Wainstein, Francesco Dotta, Piermarco Piatti, Stefano Genovese, Agostino Consoli, Paolo Di Bartolo, Edoardo Mannucci, Carla Giordano, Annunziata Lapolla, Carlos Aguilar, Alberto Esteban, Bazzoni Ruiz, Guillermo Mondragon Ramirez, Emilia Pelayo Orozco, Carlos Alejandro, Stobschinski de Alba, Carlos Medina Pech, Jose Garza Ruiz, Leobardo Sauque Reyna, Guillermo Llamas Esperon, Luis Alejandro Nevarez Ruiz, Maricela Vidrio Velazquez, Fernando Flores Lozano, Jose Gerardo Gonzalez Gonzalez, Pedro Alberto Garcia-Hernandez, Roberto Araujo-Silva, Efrain Villeda - Espinosa, Cristina Mistodie, Daniela Popescu, Ciprian Constantin, Alina Nicolau, Bogdan Popa, Romulus Timar, Cristian Serafinceanu, Ella Pintilei, Alfonso Soto, Margarita Gimenez, Juan Francisco Merino-Torres, Cristobal Morales, Pedro Mezquita, Johan Jendle, Bengt-Olov Tengmark, Jan Eriksson, Magnus Londahl, Bjorn Eliasson, Anthony Gunstone, Simon Heller, Ken Darzy, Peter Mansell, Melanie Davies, Rory Reed, Duncan Browne, Hamish Courtney, Wayne Turner, Mark Blagden, Rory McCrimmon, Richard Bergenstal, Wendy Lane, Kathryn Lucas, Alexander White, Shichun Bao, Judith White, Curtis Jantzi, Neda Rasouli, William Ervin, Lorena Lewy-Alterbaum, Yehuda Handelsman, Bresta Miranda-Palma, Alan Cleland, Raymond Fink, Helena Rodbard, Samer Nakhle, Craig Greenberg, Alan Schorr, Harold Bays, Debra Simmons, Eric Klein, Laurie Kane, Norman Fishman, Eli Ipp, Satish Garg, Anuj Bhargava, Michelle Zaniewski Singh, Julio Rosenstock, James Thrasher, Mark Warren, Laura Young, Vanita Aroda, Jeremy Pettus, David Liljenquist, Robert Busch, Jonathan Wise, David Kayne, William Biggs, Dandona P., Mathieu C., Phillip M., Hansen L., Griffen S.C., Tschope D., Thoren F., Xu J., Langkilde A.M., Proietto J., Stranks S., Chen R., O'Neal D., Pape A., Forbes M., Morbey C., Luger A., Hanusch U., Schnack C., Fliesser-Goerzer E., Hoelzl B., Ebenbichler C., Prager R., Van Gaal L., Vercammen C., Scheen A., Duyck F., Nobels F., Ruige J., Aggarwal N., Woo V., St-Pierre B., Dumas R., Hramiak I., Elliott T., Krarup Hansen T., Henriksen J.E., Gram J., Lihn A., Bruun J., Saltevo J., Taurio J., Strand J., Valle T., Nieminen S., Pietilainen K., Guerci B., Hadjadj S., Cariou B., Verges B., Borot S., Penfornis A., Schaum T., Tschoepe D., Marck C., Horacek T., Rose L., Klausmann G., Luedemann J., Appelt S., Aigner U., Goebel R., Behnke T., Ziegler A.-G., Peterfai E., Kerenyi Z., Oroszlan T., Kiss G.G., Konyves L., Piros G., Mosenzon O., Shehadeh N., Adawi F., Wainstein J., Dotta F., Piatti P., Genovese S., Consoli A., Di Bartolo P., Mannucci E., Giordano C., Lapolla A., Aguilar C., Esteban A., Ruiz B., Ramirez G.M., Pelayo Orozco E., Alejandro C., de Alba S., Medina Pech C., Garza Ruiz J., Sauque Reyna L., Llamas Esperon G., Nevarez Ruiz L.A., Vidrio Velazquez M., Flores Lozano F., Gonzalez Gonzalez J.G., Garcia-Hernandez P.A., Araujo-Silva R., Villeda - Espinosa E., Mistodie C., Popescu D., Constantin C., Nicolau A., Popa B., Timar R., Serafinceanu C., Pintilei E., Soto A., Gimenez M., Merino J., Morales C., Mezquita P., Jendle J., Tengmark B.-O., Eriksson J., Londahl M., Eliasson B., Gunstone A., Heller S., Darzy K., Mansell P., Davies M., Reed R., Browne D., Courtney H., Turner W., Blagden M., McCrimmon R., Bergenstal R., Lane W., Lucas K., White A., Bao S., White J., Jantzi C., Rasouli N., Ervin W., Lewy-Alterbaum L., Handelsman Y., Miranda-Palma B., Cleland A., Fink R., Rodbard H., Nakhle S., Greenberg C., Schorr A., Bays H., Simmons D., Klein E., Kane L., Fishman N., Ipp E., Garg S., Bhargava A., Singh M.Z., Rosenstock J., Thrasher J., Warren M., Young L., Aroda V., Pettus J., Liljenquist D., Busch R., Wise J., Kayne D., and Biggs W.
Subjects: Male, Glycated Hemoglobin A, Endocrinology, Diabetes and Metabolism, Type 2 diabetes, 030204 cardiovascular system & hematology, Settore MED/13 - Endocrinologia, law.invention, chemistry.chemical_compound, 0302 clinical medicine, Endocrinology, diabetes, dapaglifozin, Glucosides, Randomized controlled trial, law, Insulin, 03.02. Klinikai orvostan, Dapagliflozin, Middle Aged, Diabetes and Metabolism, Treatment Outcome, Combination, Drug Therapy, Combination, Female, Type 1, Adult, medicine.medical_specialty, Diabetic ketoacidosis, 030209 endocrinology & metabolism, Placebo, 03 medical and health sciences, Drug Therapy, Diabetes management, Diabetes mellitus, Internal medicine, Diabetes Mellitus, Internal Medicine, medicine, Humans, Hypoglycemic Agents, Benzhydryl Compounds, Body Weight, Diabetes Mellitus, Type 1, Hypoglycemia, Glycated Hemoglobin, Type 1 diabetes, business.industry, medicine.disease, Surgery, chemistry, business
Abstract: Background Dapagliflozin is a sodium-glucose cotransporter-2 inhibitor approved for the treatment of type 2 diabetes. We aimed to assess the efficacy and safety of dapagliflozin as an add-on to adjustable insulin in patients with inadequately controlled type 1 diabetes. Methods DEPICT-1 was a double-blind, randomised, parallel-controlled, three-arm, phase 3, multicentre study done at 143 sites in 17 countries. Eligible patients were aged 18–75 years and had inadequately controlled type 1 diabetes (HbA1c between ≥7·7% and ≤11·0% [≥61·0 mmol/mol and ≤97·0 mmol/mol]) and had been prescribed insulin for at least 12 months before enrolment. After an 8 week lead-in period to optimise diabetes management, patients were randomly assigned (1:1:1) using an interactive voice response system to dapagliflozin 5 mg or 10 mg once daily, given orally, or matched placebo. Randomisation was stratified by current use of continuous glucose monitoring, method of insulin administration, and baseline HbA1c. The primary efficacy outcome was the change from baseline in HbA1c after 24 weeks of treatment in the full analysis set, which consisted of all randomly assigned patients who received at least one dose of study drug. An additional 55 patients who were incorrectly and non-randomly allocated to only dapagliflozin treatment groups were included in the safety analysis set. This study was registered with ClinicalTrials.gov, number NCT02268214; data collection for the present analysis was completed on Jan 4, 2017, and a 28 week extension phase is ongoing. Findings Between Nov 11, 2014, and April 16, 2016, 833 patients were assigned to treatment groups and included in safety analyses (dapagliflozin 5 mg [n=277] vs dapagliflozin 10 mg [n=296] vs placebo [n=260]; 778 of these patients were randomly assigned and included in the full analysis set for efficacy analyses (259 vs 259 vs 260; difference due to randomisation error affecting 55 patients). Mean baseline HbA1c was 8·53% (70 mmol/mol; SD 0·67% [7·3 mmol/mol]). At week 24, both doses of dapagliflozin significantly reduced HbA1c compared with placebo (mean difference from baseline to week 24 for dapagliflozin 5 mg vs placebo was −0·42% [95% CI −0·56 to −0·28; p
Published: 2017

10. Case report: Assessing criminal responsibility and recidivism risk in the behavioral variant of frontotemporal dementia.

Author: Karcher A, Hamza R, and Jantzi C
Abstract: Frontotemporal dementia (FTD) affects the frontal and temporal lobes of the brain, leading to personality changes, language impairments, and behavioral disturbances, including impulsivity and disinhibition. Assessing responsibility and recidivism risk in forensic evaluations is challenging due to the evolving nature of FTD. Despite limited literature, we present a case of a 45-year-old man with no prior legal or medical history, who committed criminal acts due to behavioral changes linked to the behavioral variant of frontotemporal dementia (bvFTD). Initial assessment found him irresponsible, with a non-evaluable risk of recidivism. Subsequent evaluation showed a low recidivism risk based on clinical evolution. We discuss these findings considering existing literature and Swiss jurisprudence., Competing Interests: The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest., (Copyright © 2024 Karcher, Hamza and Jantzi.)
Published: 2024
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11. New Measurements of the Beam-Normal Single Spin Asymmetry in Elastic Electron Scattering over a Range of Spin-0 Nuclei.

Author: Adhikari D, Albataineh H, Androic D, Aniol K, Armstrong DS, Averett T, Ayerbe Gayoso C, Barcus S, Bellini V, Beminiwattha RS, Benesch JF, Bhatt H, Bhatta Pathak D, Bhetuwal D, Blaikie B, Boyd J, Campagna Q, Camsonne A, Cates GD, Chen Y, Clarke C, Cornejo JC, Covrig Dusa S, Dalton MM, Datta P, Deshpande A, Dutta D, Feldman C, Fuchey E, Gal C, Gaskell D, Gautam T, Gericke M, Ghosh C, Halilovic I, Hansen JO, Hauenstein F, Henry W, Horowitz CJ, Jantzi C, Jian S, Johnston S, Jones DC, Karki B, Kakkar S, Katugampola S, Keppel CE, King PM, King DE, Knauss M, Kumar KS, Kutz T, Lashley-Colthirst N, Leverick G, Liu H, Liyange N, Malace S, Mammei J, Mammei R, McCaughan M, McNulty D, Meekins D, Metts C, Michaels R, Mihovilovic M, Mondal MM, Napolitano J, Nikolaev D, Rashad MNH, Owen V, Palatchi C, Pan J, Pandey B, Park S, Paschke KD, Petrusky M, Pitt ML, Premathilake S, Puckett AJR, Quinn B, Radloff R, Rahman S, Rathnayake A, Reed BT, Reimer PE, Richards R, Riordan S, Roblin Y, Seeds S, Shahinyan A, Souder PA, Tang L, Thiel M, Tian Y, Urciuoli GM, Wertz EW, Wojtsekhowski B, Xiong W, Yale B, Ye T, Zec A, Zhang W, Zhang J, and Zheng X
Abstract: We report precision determinations of the beam-normal single spin asymmetries (A_{n}) in the elastic scattering of 0.95 and 2.18 GeV electrons off ^{12}C, ^{40}Ca, ^{48}Ca, and ^{208}Pb at very forward angles where the most detailed theoretical calculations have been performed. The first measurements of A_{n} for ^{40}Ca and ^{48}Ca are found to be similar to that of ^{12}C, consistent with expectations and thus demonstrating the validity of theoretical calculations for nuclei with Z≤20. We also report A_{n} for ^{208}Pb at two new momentum transfers (Q^{2}) extending the previous measurement. Our new data confirm the surprising result previously reported, with all three data points showing significant disagreement with the results from the Z≤20 nuclei. These data confirm our basic understanding of the underlying dynamics that govern A_{n} for nuclei containing ≲50 nucleons, but point to the need for further investigation to understand the unusual A_{n} behavior discovered for scattering off ^{208}Pb.
Published: 2022
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12. Attempted altruistic infanticide in a context of psychotic decompensation induced by stress linked to the COVID-19pandemic: a case report.

Author: Jantzi C and Perrin A
Abstract: The mediatization of the COVID-19 pandemic has created a lot of stress leading sometimes to mental health issues. We present a case of a thirty-year-old woman with no history of psychotic disease but some vulnerabilities and no criminal record, who attempted to kill her seven-year-old son during a brief delusional episode in the context of fear of the coronavirus. She was successfully treated by pharmacotherapy and psychotherapy. She was examined by forensic psychiatrists leading to the conclusion that her responsibility was highly diminished, and her reoffending risk was low. We add to the literature that the COVID-19 pandemic has been such a stressor for mentally vulnerable people that it could lead to severe psychiatric decompensation and even criminal acts., Competing Interests: The authors declare no conflicts of interest., (© 2021 The Author(s). Published by Taylor & Francis Group on behalf of the Academy of Forensic Science.)
Published: 2021
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13. Psychiatric Commitment: Sixty Years Under the Scrutiny of the European Court of Human Rights.

Author: Niveau G, Jantzi C, and Godet T
Abstract: Background and Aims: In the field of mental health, the fundamental right to liberty is a point of tension between the practice of psychiatric commitment on the one hand and the universal concept of human rights on the other. The European Court of Human Rights (ECtHR) is a very specific means of safeguarding human rights because it allows an individual to not only assert their rights but also compel a state to bring its legislation into conformity with the principles of the European Convention on Human Rights. The aim of this study was to gather the case-law of the ECtHR on psychiatric commitment over the last 60 years and to determine how this case-law has affected national legislation and therefore psychiatric practice. Methods: Jurisprudence data were collected from the HUDOC ECtHR database, and the direct effects of the ECtHR judgements on the legislations of the countries concerned were collected from the HUDOC EXEC database of the Council of Europe. The case-law of the Court included 118 judgements and 56 decisions and concerned 31 of the 45 countries that have ratified the Convention. Results: This study therefore showed a direct effect of the Court's case-law on the legislation on psychiatric commitment in the various countries that have ratified the Convention. It was also possible to detect an indirect effect of this case-law through the directives of international institutions such as the directives of the Committee of Ministers of the Council of Europe concerning respect for people with mental disorders. Conclusions: The ECtHR case-law therefore has a major influence on the psychiatric practice in all Council of Europe countries., Competing Interests: The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest., (Copyright © 2021 Niveau, Jantzi and Godet.)
Published: 2021
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14. Retrieval practice improves memory in patients with schizophrenia: new perspectives for cognitive remediation.

Author: Jantzi C, Mengin AC, Serfaty D, Bacon E, Elowe J, Severac F, Meyer N, Berna F, and Vidailhet P
Subjects: Adult, Bayes Theorem, Cues, Female, Humans, Male, Memory, Episodic, Mental Recall, Schizophrenia complications, Young Adult, Cognitive Remediation methods, Memory Disorders therapy, Schizophrenia therapy, Verbal Learning
Abstract: Background: Schizophrenia is associated with severe cognitive deficits, particularly episodic memory deficits, that interfere with patients' socio-professional functioning. Retrieval practice (also known as testing effect) is a well-established episodic memory strategy that involves taking an initial memory test on a previously learned material. Testing later produces robust long-term memory improvements in comparison to the restudy of the same material both in healthy subjects and in some clinical populations with memory deficits. While retrieval practice might represent a relevant cognitive remediation strategy in patients with schizophrenia, studies using optimal procedures to explore the benefits of retrieval practice in this population are still lacking. Therefore, the purpose of our study was to investigate the benefits of retrieval practice in patients with schizophrenia., Methods: Nineteen stabilised outpatients with schizophrenia (DSM-5 criteria) and 20 healthy controls first studied a list of 60 word-pairs (30 pairs with weak semantic association and 30 non associated pairs). Half the pairs were studied again (restudy condition), while only the first word of the pair was presented and the subject had to recall the second word for the other half (retrieval practice condition). The final memory test consisted in a cued-recall which took place 2 days later. Statistical analyses were performed using Bayesian methods., Results: Cognitive performances were globally altered in patients. However, in both groups, memory performances for word-pairs were significantly better after retrieval practice than after restudy (56.1% vs 35.7%, respectively, Pr(RP > RS) > 0.999), and when a weak semantic association was present (64.7% vs 27.1%, respectively; Pr(weak > no) > 0.999). Moreover, the positive effect of RP was observed in all patients but one., Conclusions: Our study is the first to demonstrate that retrieval practice efficiently improves episodic memory in comparison to restudy in patients with schizophrenia. This learning strategy should therefore be considered as a useful tool for cognitive remediation programs. In this perspective, future studies might explore retrieval practice using more ecological material.
Published: 2019
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15. Melancholia Associated With Severe Cognitive Disorders as the Expression of Late-Onset Postpartum Anti-N-Methyl-d-Aspartic Acid Receptor Limbic Encephalitis.

Author: Lalanne L, Jantzi C, Gorse A, Zimmermann MA, Danion JM, and Foucher J
Subjects: Adult, Brain diagnostic imaging, Brain pathology, Female, Fluorodeoxyglucose F18 metabolism, Humans, Magnetic Resonance Imaging, Positron-Emission Tomography, Anti-N-Methyl-D-Aspartate Receptor Encephalitis complications, Cognition Disorders etiology, Depressive Disorder etiology, Postpartum Period
Published: 2015
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15 results on '"Jantzi C"'

1. Quasielastic $\overrightarrow{^{3}\mathrm{He}}(\overrightarrow{e},{e'})$ Asymmetry in the Threshold Region

2. Precision Determination of the Neutral Weak Form Factor of $^{48}$Ca

3. New Measurements of the Beam-Normal Single Spin Asymmetry in Elastic Electron Scattering Over a Range of Spin-0 Nuclei

4. Accurate Determination of the Neutron Skin Thickness of $^{208}$Pb through Parity-Violation in Electron Scattering

5. New Measurements of the Beam-Normal Single Spin Asymmetry in Elastic Electron Scattering Over a Range of Spin-0 Nuclei

6. Linagliptin Effects on Heart Failure and Related Outcomes in Individuals With Type 2 Diabetes Mellitus at High Cardiovascular and Renal Risk in CARMELINA

7. Effect of Linagliptin vs Placebo on Major Cardiovascular Events in Adults With Type 2 Diabetes and High Cardiovascular and Renal Risk The CARMELINA Randomized Clinical Trial

8. Vocal frequency suppression apparatus and method

9. Efficacy and safety of dapagliflozin in patients with inadequately controlled type 1 diabetes (DEPICT-1): 24 week results from a multicentre, double-blind, phase 3, randomised controlled trial

10. Case report: Assessing criminal responsibility and recidivism risk in the behavioral variant of frontotemporal dementia.

11. New Measurements of the Beam-Normal Single Spin Asymmetry in Elastic Electron Scattering over a Range of Spin-0 Nuclei.

12. Attempted altruistic infanticide in a context of psychotic decompensation induced by stress linked to the COVID-19pandemic: a case report.

13. Psychiatric Commitment: Sixty Years Under the Scrutiny of the European Court of Human Rights.

14. Retrieval practice improves memory in patients with schizophrenia: new perspectives for cognitive remediation.

15. Melancholia Associated With Severe Cognitive Disorders as the Expression of Late-Onset Postpartum Anti-N-Methyl-d-Aspartic Acid Receptor Limbic Encephalitis.

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