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10. Diabetes mellitus in long‐term survivors with colorectal, breast, or prostate cancer: Prevalence and prognosis. A population‐based study

Author

Yang, Keyi, primary, Doege, Daniela, additional, Thong, Melissa S. Y., additional, Koch‐Gallenkamp, Lena, additional, Weisser, Linda, additional, Bertram, Heike, additional, Eberle, Andrea, additional, Holleczek, Bernd, additional, Nennecke, Alice, additional, Waldmann, Annika, additional, Zeissig, Sylke Ruth, additional, Pritzkuleit, Ron, additional, Jansen, Lina, additional, Brenner, Hermann, additional, and Arndt, Volker, additional

Published
2023
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13. Age-specific health-related quality of life in disease-free long-term prostate cancer survivors versus male population controls—results from a population-based study

Author

Adam, Salome, Doege, Daniela, Koch-Gallenkamp, Lena, Thong, Melissa S. Y., Bertram, Heike, Eberle, Andrea, Holleczek, Bernd, Pritzkuleit, Ron, Waldeyer-Sauerland, Mechthild, Waldmann, Annika, Zeissig, Sylke Ruth, Jansen, Lina, Rohrmann, Sabine, Brenner, Hermann, and Arndt, Volker

Published
2020
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16. Selbst berichtete Infektionen in der NAKO Gesundheitsstudie – Einordnung in die gegenwärtige Forschungslandschaft

Author

Hassenstein, Max J, Aarabi, Ghazal, Ahnert, Peter, Becher, Heiko, Franzke, Claus-Werner, Fricke, Julia, Krause, Gérard, Glöckner, Stephan, Gottschick, Cornelia, Karch, André, Kemmling, Yvonne, Kerrinnes, Tobias, Lange, Berit, Mikolajczyk, Rafael, Nieters, Alexandra, Ott, Jördis J, Ahrens, Wolfgang, Berger, Klaus, Meinke-Franze, Claudia, Gastell, Sylvia, Günther, Kathrin, Greiser, Karin Halina, Holleczek, Bernd, Horn, Johannes, Jaeschke, Lina, Jagodzinski, Annika, Jansen, Lina, Jochem, Carmen, Jöckel, Karl-Heinz, Kaaks, Rudolf, Krist, Lilian, Kuß, Oliver, Langer, Susan, Legath, Nicole, Leitzmann, Michael, Lieb, Wolfgang, Loeffler, Markus, Mangold, Nina, Michels, Karin B., Meisinger, Christa, Obi, Nadia, Pischon, Tobias, Schikowski, Tamara, Schipf, Sabine, Schulze, Matthias B., Stang, Andreas, Waniek, Sabina, Wirkner, Kerstin, Willich, Stefan N., and Castell, Stefanie

Published
2020
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17. Association Between Intake of Red and Processed Meat and Survival in Patients With Colorectal Cancer in a Pooled Analysis

Author

Carr, Prudence R., Banbury, Barbara L., Berndt, Sonja I., Campbell, Peter T., Chang-Claude, Jenny, Hayes, Richard B., Howard, Barbara V., Jansen, Lina, Jacobs, Eric J., Lane, Dorothy S., Nishihara, Reiko, Ogino, Shuji, Phipps, Amanda I., Slattery, Martha L., Stefanick, Marcia L., Wallace, Robert, Walter, Viola, White, Emily, Wu, Kana, Peters, Ulrike, Chan, Andrew T., Newcomb, Polly A., Brenner, Hermann, and Hoffmeister, Michael

Published
2019
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22. Diabetes mellitus in long‐term survivors with colorectal, breast, or prostate cancer: Prevalence and prognosis. A population‐based study.

Author

Yang, Keyi, Doege, Daniela, Thong, Melissa S. Y., Koch‐Gallenkamp, Lena, Weisser, Linda, Bertram, Heike, Eberle, Andrea, Holleczek, Bernd, Nennecke, Alice, Waldmann, Annika, Zeissig, Sylke Ruth, Pritzkuleit, Ron, Jansen, Lina, Brenner, Hermann, and Arndt, Volker

Subjects
PROSTATE cancer prognosis, DIABETES, CANCER survivors, CANCER fatigue, PROSTATE cancer, BODY mass index, SEDENTARY behavior
Abstract

Background: Patients with cancer are at increased risk of diabetes mellitus (DM). Previous studies on the prevalence and prognostic impact of DM in cancer survivors were limited by small sample sizes or short follow‐up times. We aimed to compare the patient‐reported prevalence of DM in long‐term cancer survivors (LTCS), who survived 5 years or more after cancer diagnosis, with that in cancer‐free controls, and to estimate the mortality risk among LTCS according to DM status. Methods: Our population‐based cohort comprised 6952 LTCS diagnosed with breast, colorectal, or prostate cancer between 1994 and 2004, recruited in 2008–2011 (baseline), and followed until 2019. A total of 1828 cancer‐free individuals served as controls. Multivariable logistic regression was used to compare the prevalence of DM in LTCS and controls, and according to covariates at baseline. Mortality among LTCS according to DM was assessed by Cox proportional hazards regression. Results: A total of 962 (13.8%) LTCS at baseline reported DM. Prevalence of DM in LTCS was not higher than in cancer‐free controls, both at baseline (odds ratio, 0.80; 95% CI, 0.66–0.97) and at follow‐up (odds ratio, 0.83; 95% CI, 0.67–1.04). Prevalence of DM in LTCS was associated with cancer site, older age, lower education, higher socioeconomic deprivation, higher body mass index, physical inactivity, other comorbidities, and poorer prognosis (adjusted hazard ratio [all‐cause mortality] = 1.29; 95% CI, 1.15–1.44). Conclusion: DM in LTCS is prevalent, but not higher than in cancer‐free population controls. Cancer survivors with concurrent DM are at a potentially higher risk of death. Plain Language Summary: Cancer and diabetes mellitus (DM) are two serious threats to global health.In our study, prevalence of DM in long‐term cancer survivors who survived 5 years or more after cancer diagnosis was not higher than in cancer‐free controls.This should not be interpreted as an indication of a lower risk of DM in cancer survivors. Rather, it highlights the potentially poor prognosis in diabetic cancer survivors. Therefore, keeping a continuous satisfactory DM and hyperglycemia management is essential during long‐term cancer survivorship. This study examined the prevalence and impact of diabetes mellitus (DM) in long‐term cancer survivors (LTCS) who had survived more than 5 years after cancer diagnosis. Findings revealed a 13.8% prevalence of DM in LTCS, which is not higher than in the cancer‐free controls, yet LTCS with DM had a potentially increased risk of mortality, indicating the importance of managing this comorbidity in survivorship care. [ABSTRACT FROM AUTHOR]

Published
2024
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23. Trends in cancer incidence by socioeconomic deprivation in Germany in 2007 to 2018: An ecological registry‐based study

Author

Jansen, Lina, primary, Schwettmann, Lars, additional, Behr, Christian, additional, Eberle, Andrea, additional, Holleczek, Bernd, additional, Justenhoven, Christina, additional, Kajüter, Hiltraud, additional, Manz, Kirsi, additional, Peters, Frederik, additional, Pritzkuleit, Ron, additional, Schmidt‐Pokrzywniak, Andrea, additional, Sirri, Eunice, additional, Tetzlaff, Fabian, additional, Voigtländer, Sven, additional, and Arndt, Volker, additional

Published
2023
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30. Survival for patients with rare haematologic malignancies: Changes in the early 21st century

Author

Geiss, Karla, Meyer, Martin, Eberle, Andrea, Luttmann, Sabine, Stabenow, Roland, Hentschel, Stefan, Nennecke, Alice, Kieschke, Joachim, Sirri, Eunice, Holleczek, Bernd, Emrich, Katharina, Kajüter, Hiltraud, Mattauch, Volkmar, Katalinic, Alexander, Eisemann, Nora, Barnes, Benjamin, Kraywinkel, Klaus, Brenner, Hermann, Jansen, Lina, Weberpals, Janick, Pulte, Dianne, and Ressing, Meike

Published
2017
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36. Characteristics, Treatment Patterns and Survival of International Federation of Gynecology and Obstetrics Stage IV Epithelial Ovarian Cancer—A Population-Based Study.

Author

Jakob, Dorothee, Schmoor, Claudia, Reuten, Raphael, Frevert, Marie Louise, Dannehl, Dominik, Jansen, Lina, Hermann, Silke, Jungmann, Peter, Hartkopf, Andreas Daniel, Juhasz-Böss, Ingolf, and Taran, Florin Andrei

Subjects
PATIENT aftercare, CONFIDENCE intervals, OVARIAN epithelial cancer, TUMOR classification, SURVIVAL rate, SYMPTOMS, DESCRIPTIVE statistics
Abstract

Simple Summary: Ovarian cancer (OC) is the most lethal gynecologic malignancy, with a relative 5-year survival rate of between 40% and 50%. We used the Cancer Registry of Baden-Württemberg to identify characteristics, treatment patterns and survival of OC patients with International Federation of Gynecology and Obstetrics (FIGO) stage IV who were registered over a period of 8 years (2012–2019). The aim of the present analysis was to describe an unselected patient population with primary diagnoses of FIGO stage IV OC with respect to baseline patient and tumor characteristics, treatment strategies and prognosis in terms of overall survival. In this cohort of patients with FIGO stage IV OC, more than 80% of the patients received cancer-directed treatment. Age and high-grade serous histology were determinants for survival. The highest overall survival rate was observed in patients who underwent surgery followed by systemic treatment. Background: The aim of the present study was to describe an unselected population of patients with diagnosis of FIGO stage IV OC. Methods: Data from 1183 patients were available for analysis. Results: The majority of patients (962/1183, 81.3%) received cancer-directed treatment. The median follow-up time was 3.8 years, and the median overall survival duration was 1.9 years. Notably, patients >80 years had a low overall survival rate (HR of age >80 years vs. ≤50 years was 3.81, 95%-CI [2.76, 5.27], p < 0.0001). The survival rate was best in patients with HGSOC (p < 0.0001). The highest overall survival rate was observed in patients in the group with surgical intervention followed by systemic treatment, with an unadjusted HR of 0.72, 95%-CI [0.59, 0.86], p = 0.007 vs. systemic treatment only. After adjustment for age and histology, survival differences between treatment schemes were smaller (HR 0.81, 95%-CI [0.66, 1.00], p = 0.12). Conclusions: In this cohort of patients with FIGO stage IV OC, more than 80% of the patients received cancer-directed treatment. Age and high-grade serous histology were determinants for survival. The highest overall survival rate was observed in patients who underwent surgery followed by systemic treatment. [ABSTRACT FROM AUTHOR]

Published
2023
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