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11. Editors' Introduction

Author

Doortmont, Michel R., Jansen, Jan, Hanson, John H., and van den Bersselaar, Dmitri

Published
2018

13. Best Case/Worst Case-ICU: protocol for a multisite, stepped-wedge, randomised clinical trial of scenario planning to improve communication in the ICU in US trauma centres for older adults with serious injury.

Author

Stalter, Lily, Hanlon, Bret, Bushaw, Kyle, Kwekkeboom, Kristine, Zelenski, Amy, Fritz, Melanie, Buffington, Anne, Stein, Deborah, Cocanour, Christine, Robles, Anamaria, Jansen, Jan, Brasel, Karen, OConnell, Kathleen, Cipolle, Mark, Ayoung-Chee, Patricia, Morris, Rachel, Gelbard, Rondi, Kozar, Rosemary, Lueckel, Stephanie, and Schwarze, Margaret

Subjects
adult intensive & critical care, clinical trial, medical ethics, palliative care, trauma management, Aged, Female, Humans, Male, Middle Aged, Communication, Family, Intensive Care Units, Randomized Controlled Trials as Topic, Trauma Centers, United States, Wounds and Injuries, Multicenter Studies as Topic
Abstract

INTRODUCTION: Poor communication about serious injury in older adults can lead to treatment that is inconsistent with patient preferences, create conflict and strain healthcare resources. We developed a communication intervention called Best Case/Worst Case-intensive care unit (ICU) that uses daily scenario planning, that is, a narrative description of plausible futures, to support prognostication and facilitate dialogue among patients, their families and the trauma ICU team. This article describes a protocol for a multisite, randomised, stepped-wedge study to test the effectiveness of the intervention on the quality of communication (QOC) in the ICU. METHODS AND ANALYSIS: We will follow all patients aged 50 and older admitted to the trauma ICU for 3 or more days after a serious injury at eight high-volume level 1 trauma centres. We aim to survey one family or like family member per eligible patient 5-7 days following their loved ones admission and clinicians providing care in the trauma ICU. Using a stepped-wedge design, we will use permuted block randomisation to assign the timing for each site to begin implementation of the intervention and routine use of the Best Case/Worst Case-ICU tool. We will use a linear mixed-effects model to test the effect of the tool on family-reported QOC (using the QOC scale) as compared with usual care. Secondary outcomes include the effect of the tool on reducing clinician moral distress (using the Measure of Moral Distress for Healthcare Professionals scale) and patients length of stay in the ICU. ETHICS AND DISSEMINATION: Institutional review board (IRB) approval was granted at the University of Wisconsin, and all study sites ceded review to the primary IRB. We plan to report results in peer-reviewed publications and national meetings. TRIAL REGISTRATION NUMBER: NCT05780918.

Published
2024

39. Open Access Capture of Patients With Gastroesophageal Reflux Disease Using an Online Patient-Reported Outcomes Instrument

Author

Tielemans, Merel M, Jansen, Jan BMJ, and van Oijen, Martijn GH

Subjects
Computer applications to medicine. Medical informatics, R858-859.7, Medical technology, R855-855.5
Abstract

BackgroundPersons with gastroesophageal reflux disease (GERD) frequently search online for information about causes and treatment options. The GerdQ self-assessment questionnaire can be used for diagnosis of GERD and follow-up of symptoms. ObjectivesTo assess whether it is feasible (1) to study the prevalence and impact of GERD in persons visiting a GERD information website, and (2) to identify partial responsiveness to proton pump inhibitor (PPI) therapy using the GerdQ. MethodsAll visitors (aged 18–79 years) to a GERD information website between November 2008 and May 2011 were invited to complete the GerdQ online. The GerdQ questionnaire consists of 6 questions (score per question: 0–3). In respondents who did not use PPIs, we used the questionnaire to identify those with GERD (total score ≥8) and assess the influence of these symptoms on their daily life, divided into low (total score

Published
2012
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41. EURADOS Intercomparison on the Usage of the ICRP/ICRU Adult Reference Computational Phantoms

Author

Zankl, Maria, Eakins, Jonathan, Ros, Jose-Maria Gomez, Huet, Christelle, Jansen, Jan, Moraleda, Montserrat, Reichelt, Uwe, Struelens, Lara, and Vrba, Tomas

Subjects
Physics - Medical Physics, Physics - Computational Physics
Abstract

The European Radiation Dosimetry Group, EURADOS, has organised an intercomparison study on the usage of the ICRP/ICRU voxel reference computational phantoms together with radiation transport codes. Voluntary participants have been invited to solve specific tasks and provide solutions to the organisers before a certain deadline. The tasks to be solved are of practical interest in occupational, environmental and medical dosimetry. The aims of this training activity were to investigate if the phantoms have been correctly implemented in the radiation transport codes and to give the participants the opportunity to check their own calculations against quality-assured master solutions and improve their approach, if needed., Comment: 10 pages, one figure, final manuscript accepted for publication

Published
2021
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43. Unraveling factors associated with textbook outcome after cholecystectomy in patients with uncomplicated cholecystolithiasis: A posthoc analysis of individual data of 1,124 patients

Author

Buyne, Otmar, Donkervoort, Sandra C., Heisterkamp, Joos, Hof, Klaas in ‘t, Diepenhorst, Gwen, van der Bilt, Jarmila, Jansen, Jan, Nieuwenhuijs, Vincent B., Steenvoorde, Pascal, Boerma, Djamila, Heikens, Joost T., Schreinemakers, Jennifer M.J., Wiering, Bastiaan, Stockmann, Hein B.A.C., van Duijvendijk, Peter, Boermeester, Marja A., Comes, Daan J., Thunnissen, Floris M., Latenstein, Carmen S.S., Stommel, Martijn W.J., van Laarhoven, Cornelis J.H.M., Drenth, Joost P.H., Atsma, Femke, Lantinga, Marten A., and de Reuver, Philip R.

Published
2024
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48. Results from the UNITED study: a multicenter study validating the prognostic effect of the tumor–stroma ratio in colon cancer

Author

Petrushevska, Gordana, Bogdanovska, Magdalena, Zdravkoski, Panche, Antovic, Svetozar, Dzambaz, Darko, Karagjozov, Panche, de Cuba, Erienne M.V., Beverdam, Frédérique, Jansen, Jan, Vermaas, Maarten, Gašljević, Gorana, Kjær-Frifeldt, Sanne, Lindebjerg, Jan, Strous, Maud, Vogelaar, Jeroen F., Bulkmans, Nicole W.J., van Baarlen, Joop, Mekenkamp, Leonie, Hoekstra, Ronald, Sie, Mark, Cuatrecasas, Miriam, Simonetti, Sara, Rodrigo, María Teresa, Sanz, Iván Archilla, Guerrero Pineda, Jose, Leeuwis-Fedorovich, Natalja E., Talsma, Koen A., Souza da Silva, Ricella M., Lacle, Miangela M., Koopman, Miriam, Dekker, Jan Willem T., van Tilburg, Arjan, Nuciforo, Paolo, Villalobos Alberú, Xenia, Landolfi, Stefania, Zucchiatti, Adriana, Witteveen, Emma, Bordbar, Arad, Hendriks, Mathijs P., Arensman, René, Natu, Shonali, Maka, Noori, Mesker, Wilma E., Tollenaar, Rob A.E.M., Polack, Meaghan, Smit, Marloes A., van Pelt, Gabi W., Putter, Hein, Meershoek-Kleinenbarg, Elma, Roodvoets, Annet G.H., Crobach, Augustinus S.L.P., Gelderblom, Hans, Fontes e Sousa, Mário, Borralho Nunes, Paula, Cruz, João, Raimundo, Ana, Silva, Nelson, Brito, Maria J., Terpstra, Valeska, Zakhartseva, L.M., Al Dieri, Raed, Fléjou, Jean-François, Feakins, Roger, Dequeker, Els, Vink, Geraldine R., van Krieken, J.Han J.M., Polack, M., Smit, M.A., van Pelt, G.W., Roodvoets, A.G.H., Meershoek-Klein Kranenbarg, E., Putter, H., Gelderblom, H., Crobach, A.S.L.P., Terpstra, V., Petrushevska, G., Gašljević, G., Kjær-Frifeldt, S., de Cuba, E.M.V., Bulkmans, N.W.J., Vink, G.R., Al Dieri, R., Tollenaar, R.A.E.M., van Krieken, J.H.J.M., and Mesker, W.E.

Published
2024
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50. Developing a National Trauma Research Action Plan: Results from the regulatory challenges Delphi survey

Author

Price, Michelle A., Villarreal, Cynthia L., Moreno, Ashley N., Flayter, Rochelle, Herrera-Escobar, Juan P., Sims, Carrie A., Bulger, Eileen M., Agler, Heather, Spring, Silver, Jonas, Rachelle Babbit, Bourg, Pamela, Bulger, Eileen M., Carlisle, Erica M., Dickert, Neal W., Duron, Vincent P., Fish, Susan S., Flayter, Rochelle, Forster, David G., Fox, Erin E., Gordon, Bruce G., Holcomb, John B., Horkheimer, Sean, Jansen, Jan, Joseph, Katherine, Kohler, Johnathan E., Kozar, Rosemary A., Lau, Yvonne, Mann-Salinas, Elizabeth, McMahon, Maria, McQueen, Alisa, Moran, Vicki, Newcomb, Anna, Nicholson, Susannah E., Odam, Kimberly, Polites, Stephanie F., Sancho, Alfredo R., Schreiber, Martin A., Silverman, Benjamin C., Slidell, Mark, Smith, Sandra, Wade, Charles E., Westby, Christian W., and Zatzick, Douglas F.

Published
2024
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