163 results on '"Janowiak P"'
Search Results
2. Land use change and forest management effects on soil carbon stocks in the Northeast U.S.
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Lucas E. Nave, Kendall DeLyser, Grant M. Domke, Scott M. Holub, Maria K. Janowiak, Adrienne B. Keller, Matthew P. Peters, Kevin A. Solarik, Brian F. Walters, and Christopher W. Swanston
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Deforestation ,Reforestation ,Forest management ,Soil carbon ,Northeast U.S. ,Forest harvest ,Environmental sciences ,GE1-350 - Abstract
Abstract Background In most regions and ecosystems, soils are the largest terrestrial carbon pool. Their potential vulnerability to climate and land use change, management, and other drivers, along with soils’ ability to mitigate climate change through carbon sequestration, makes them important to carbon balance and management. To date, most studies of soil carbon management have been based at either large or site-specific scales, resulting in either broad generalizations or narrow conclusions, respectively. Advancing the science and practice of soil carbon management requires scientific progress at intermediate scales. Here, we conducted the fifth in a series of ecoregional assessments of the effects of land use change and forest management on soil carbon stocks, this time addressing the Northeast U.S. We used synthesis approaches including (1) meta-analysis of published literature, (2) soil survey and (3) national forest inventory databases to examine overall effects and underlying drivers of deforestation, reforestation, and forest harvesting on soil carbon stocks. The three complementary data sources allowed us to quantify direction, magnitude, and uncertainty in trends. Results Our meta-analysis findings revealed regionally consistent declines in soil carbon stocks due to deforestation, whether for agriculture or urban development. Conversely, reforestation led to significant increases in soil C stocks, with variation based on specific geographic factors. Forest harvesting showed no significant effect on soil carbon stocks, regardless of place-based or practice-specific factors. Observational soil survey and national forest inventory data generally supported meta-analytic harvest trends, and provided broader context by revealing the factors that act as baseline controls on soil carbon stocks in this ecoregion of carbon-dense soils. These factors include a range of soil physical, parent material, and topographic controls, with land use and climate factors also playing a role. Conclusions Forest harvesting has limited potential to alter forest soil C stocks in either direction, in contrast to the significant changes driven by land use shifts. These findings underscore the importance of understanding soil C changes at intermediate scales, and the need for an all-lands approach to managing soil carbon for climate change mitigation in the Northeast U.S.
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- 2024
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3. Multiple invasive species affect germination, growth, and photosynthesis of native weeds and crops in experiments
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Magdalena Lenda, Bastian Steudel, Piotr Skórka, Zuzanna B. Zagrodzka, Dawid Moroń, Renata Bączek-Kwinta, Franciszek Janowiak, Agnieszka Baran, Hugh P. Possingham, and Johannes M. H. Knops
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Medicine ,Science - Abstract
Abstract Alien plant species regularly and simultaneously invade agricultural landscapes and ecosystems; however, the effects of co-invasion on crop production and native biodiversity have rarely been studied. Secondary metabolites produced by alien plants may be allelopathic; if they enter the soil, they may be transported by agricultural activities, negatively affecting crop yield and biodiversity. It is unknown whether substances from different alien species in combination have a greater impact on crops and wild plants than if they are from only one of the alien species. In this study, we used a set of common garden experiments to test the hypothesis that mixed extracts from two common invasive species have synergistic effects on crops and weeds (defined as all non-crop plants) in European agricultural fields compared to single-species extracts. We found that both the combined and individual extracts had detrimental effects on the seed germination, seedling growth, biomass, and photosynthetic performance of both crops and weeds. We found that the negative effect of mixed extracts was not additive and that crop plants were more strongly affected by invasive species extracts than the weeds. Our results are important for managing invasive species in unique ecosystems on agricultural land and preventing economic losses in yield production.
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- 2023
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4. Multiple invasive species affect germination, growth, and photosynthesis of native weeds and crops in experiments
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Lenda, Magdalena, Steudel, Bastian, Skórka, Piotr, Zagrodzka, Zuzanna B., Moroń, Dawid, Bączek-Kwinta, Renata, Janowiak, Franciszek, Baran, Agnieszka, Possingham, Hugh P., and Knops, Johannes M. H.
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- 2023
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5. Silicon improves root functioning and water management as well as alleviates oxidative stress in oilseed rape under drought conditions
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Diana Saja-Garbarz, Marta Libik-Konieczny, and Franciszek Janowiak
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Brassica napus var. napus ,water content regulation ,water deficit ,aquaporins ,abiotic stress ,Plant culture ,SB1-1110 - Abstract
IntroductionThe aim of our study was to examine how silicon regulates water uptake by oilseed rape roots under drought conditions and which components of the antioxidant system take part in alleviating stress-induced ROS generation in the roots.MethodsThe study analyzed mainly the changes in the roots and also some changes in the leaves of oilseed rape plants, including total silicon content, relative water content, osmotic potential, stomatal conductance, abscisic acid level, the accumulation of BnPIP1, BnPIP2-1-7 and BnTIP1 aquaporins, and the activity of antioxidant enzymes.Results and discussionIt was shown that plants growing in well-watered conditions and supplemented with silicon accumulate smaller amounts of this element in the roots and also have higher relative water content in the leaves compared to the control plants. It was demonstrated for the first time that BnTIP1 accumulation in oilseed rape roots is reduced under drought compared to wellwatered plants, and that this effect is intensified in plants supplemented with silicon. In addition, it was shown that silicon supplementation of oilseed rape increases catalase activity in the roots, which correlates with their high metabolic activity under drought and ultimately stimulates their growth. It was shown that silicon improves water balance in oilseed rape plants subjected to drought stress, and that an important role in these processes is played by tonoplast aquaporins. In addition, it was demonstrated that silicon reduces oxidative stress in roots under drought conditions by increasing the activity of catalase.
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- 2024
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6. Characterising Biological and Physiological Drought Signals in Diverse Parents of a Wheat Mapping Population
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Kamila Laskoś, Ilona Mieczysława Czyczyło-Mysza, Piotr Waligórski, Kinga Dziurka, Edyta Skrzypek, Marzena Warchoł, Katarzyna Juzoń-Sikora, Franciszek Janowiak, Michał Dziurka, Maciej T. Grzesiak, Stanisław Grzesiak, Steve Quarrie, and Izabela Marcińska
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abscisic acid (ABA) ,biochemical parameters ,drought ,photosynthesis ,wheat ,yield ,Biology (General) ,QH301-705.5 ,Chemistry ,QD1-999 - Abstract
Water deficit affects the growth as well as physiological and biochemical processes in plants. The aim of this study was to determine differences in physiological and biochemical responses to drought stress in two wheat cultivars—Chinese Spring (CS) and SQ1 (which are parents of a mapping population of doubled haploid lines)—and to relate these responses to final yield and agronomic traits. Drought stress was induced by withholding water for 14 days, after which plants were re-watered and maintained until harvest. Instantaneous gas exchange parameters were evaluated on the 3rd, 5th, 10th, and 14th days of seedling growth under drought. After 14 days, water content and levels of chlorophyll a+b, carotenoids, malondialdehyde, soluble carbohydrates, phenolics, salicylic acid, abscisic acid (ABA), and polyamines were measured. At final maturity, yield components (grain number and weight), biomass, straw weight, and harvest index were evaluated. Physiological and biochemical parameters of CS responded more than those of SQ1 to the 14-day drought, reflected in a greater reduction in final biomass and yield in CS. Marked biochemical differences between responses of CS and SQ1 to the drought were found for soluble carbohydrates and polyamines. These would be good candidates for testing in the mapping population for the coincidence of the genetic control of these traits and final biomass and yield.
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- 2024
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7. Strategies for laboratory professionals to drive laboratory stewardship.
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White, Terra, Wong, Wesley, Janowiak, Diane, and Hilborne, Lee
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Change management ,Clinical laboratory ,Laboratory stewardship ,Leadership ,Patient care ,Quality of health care - Abstract
Appropriate laboratory testing is critical in todays healthcare environment that aims to improve patient care while reducing cost. In recent years, laboratory stewardship has emerged as a strategy for assuring quality in laboratory medicine with the goal of providing the right test, for the right patient, at the right time. Implementing a laboratory stewardship program now presents a valuable opportunity for laboratory professionals to exercise leadership within health systems and to drive change toward realizing aims in healthcare. The proposed framework for program implementation includes 5 key elements: 1) a clear vision and organizational alignment; 2) appropriate skills for program execution and management; 3) resources to support the program; 4) incentives to motivate participation; and, 5) a plan of action that articulates program objectives and metrics. This framework builds upon principles of change management, with emphasis on engagement with clinical and administrative stakeholders and the use of clinical data as the basis for change. These strategies enable laboratory professionals to cultivate organizational support for improving laboratory use and take a leading role in providing high-quality patient care.
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- 2021
8. New Prospects for Improving Microspore Embryogenesis Induction in Highly Recalcitrant Winter Wheat Lines
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Ewa Dubas, Monika Krzewska, Ewa Surówka, Przemysław Kopeć, Agnieszka Springer, Franciszek Janowiak, Dorota Weigt, Sylwia Katarzyna Mikołajczyk, Anna Telk, and Iwona Żur
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microspore embryogenesis ,winter wheat ,macro- and micronutrients ,stress ,antioxidants ,hydrogen peroxide ,Botany ,QK1-989 - Abstract
Among various methods stimulating biological progress, double haploid (DH) technology, which utilizes the process of microspore embryogenesis (ME), is potentially the most effective. However, the process depends on complex interactions between many genetic, physiological and environmental variables, and in many cases, e.g., winter wheat, does not operate with the efficiency required for commercial use. Stress associated with low-temperature treatment, isolation and transfer to in vitro culture has been shown to disturb redox homeostasis and generate relatively high levels of reactive oxygen species (ROS), affecting microspore vitality. The aim of this study was to investigate whether controlled plant growth, specific tiller pre-treatment and culture conditions could improve the potential of microspores to cope with stress and effectively induce ME. To understand the mechanism of the stress response, hydrogen peroxide levels, total activity and the content of the most important low-molecular-weight antioxidants (glutathione and ascorbate), as well as the content of selected macro- (Mg, Ca, NA, K) and micronutrients (Mn, Zn, Fe, Cu, Mo) were determined. These analyses, combined with the cytological characteristics of the microspore suspensions, allowed us to demonstrate that an increased microspore vitality and stronger response to ME induction were associated with higher stress resistance based on more efficient ROS scavenging and nutrient management. It was shown that a modified procedure, combining a low temperature with mannitol and sodium selenate tiller pre-treatment, reduced oxidative stress and improved the effectiveness of ME in winter wheat lines.
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- 2024
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9. Involvement of Dynamic Adjustment of ABA, Proline and Sugar Levels in Rhizomes in Effective Acclimation of Solidago gigantea to Contrasting Weather and Soil Conditions in the Country of Invasion
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Renata Bączek-Kwinta, Franciszek Janowiak, Magdalena Simlat, and Jacek Antonkiewicz
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abscisic acid ,goldenrod ,invasive plant species ,osmotic adjustment ,plant acclimation ,random amplified polymorphic DNA ,Biology (General) ,QH301-705.5 ,Chemistry ,QD1-999 - Abstract
Giant goldenrod (Solidago gigantea Aiton) is one of the most invasive plant species occurring in Europe. Since little is known about the molecular mechanisms contributing to its invasiveness, we examined the natural dynamics of the content of rhizome compounds, which can be crucial for plant resistance and adaptation to environmental stress. We focused on rhizomes because they are the main vector of giant goldenrod dispersion in invaded lands. Water-soluble sugars, proline, and abscisic acid (ABA) were quantified in rhizomes, as well as ABA in the rhizosphere from three different but geographically close natural locations in Poland (50°04′11.3″ N, 19°50′40.2″ E) under extreme light, thermal, and soil conditions, in early spring, late summer, and late autumn. The genetic diversity of plants between locations was checked using the random amplified polymorphic DNA (RAPD) markers. Sugar and proline content was assayed spectrophotometrically, and abscisic acid (ABA) with the ELISA immunomethod. It can be assumed that the accumulation of sugars in giant goldenrod rhizomes facilitated the process of plant adaptation to adverse environmental conditions (high temperature and/or water scarcity) caused by extreme weather in summer and autumn. The same was true for high levels of proline and ABA in summer. On the other hand, the lowering of proline and ABA in autumn did not confirm the previous assumptions about their synthesis in rhizomes during the acquisition of frost resistance by giant goldenrod. However, in the location with intensive sunlight and most extreme soil conditions, a constant amount of ABA in rhizomes was noticed as well as its exudation into the rhizosphere. This research indicates that soluble sugars, proline, and ABA alterations in rhizomes can participate in the mechanism of acclimation of S. gigantea to specific soil and meteorological conditions in the country of invasion irrespective of plant genetic variation.
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- 2023
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10. Comprehensive care for people living with heart failure and chronic obstructive pulmonary disease—Integration of palliative care with disease-specific care: From guidelines to practice
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Anna Kowalczys, Michał Bohdan, Alina Wilkowska, Iga Pawłowska, Leszek Pawłowski, Piotr Janowiak, Ewa Jassem, Małgorzata Lelonek, Marcin Gruchała, and Piotr Sobański
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heart failure ,chronic heart failure ,chronic obstructive pulmonary disease ,palliative care ,advanced care planning ,Diseases of the circulatory (Cardiovascular) system ,RC666-701 - Abstract
Heart failure (HF) and chronic obstructive pulmonary disease (COPD) are the leading global epidemiological, clinical, social, and economic burden. Due to similar risk factors and overlapping pathophysiological pathways, the coexistence of these two diseases is common. People with severe COPD and advanced chronic HF (CHF) develop similar symptoms that aggravate if evoking mechanisms overlap. The coexistence of COPD and CHF limits the quality of life (QoL) and worsens symptom burden and mortality, more than if only one of them is present. Both conditions progress despite optimal, guidelines directed treatment, frequently exacerbate, and have a similar or worse prognosis in comparison with many malignant diseases. Palliative care (PC) is effective in QoL improvement of people with CHF and COPD and may be a valuable addition to standard treatment. The current guidelines for the management of HF and COPD emphasize the importance of early integration of PC parallel to disease-modifying therapies in people with advanced forms of both conditions. The number of patients with HF and COPD requiring PC is high and will grow in future decades necessitating further attention to research and knowledge translation in this field of practice. Care pathways for people living with concomitant HF and COPD have not been published so far. It can be hypothesized that overlapping of symptoms and similarity in disease trajectories allow to draw a model of care which will address symptoms and problems caused by either condition.
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- 2022
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11. IPF Respiratory Symptoms Management — Current Evidence
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Piotr Janowiak, Amelia Szymanowska-Narloch, and Alicja Siemińska
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breathlessness ,dyspnea ,cough ,idiopathic pulmonary fibrosis (IPF) ,non-invasive ventilation (NIV) ,high flow nasal cannula (HFNC) ,Medicine (General) ,R5-920 - Abstract
Idiopathic pulmonary fibrosis (IPF) is a progressive, chronic disease of the lungs which is characterized by heavy symptom burden, especially in the last year of life. Despite recently established anti-fibrotic treatment IPF prognosis is one of the worst among interstitial lung diseases. In this review available evidence regarding pharmacological and non-pharmacological management of the main IPF symptoms, dyspnea and cough, is presented.
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- 2022
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12. Value-Based Integrated Care (VBIC) Concept Implementation in a Real-World Setting—Problem-Based Analysis of Barriers and Challenges
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Ewa Bandurska, Weronika Ciećko, Marzena Olszewska-Karaban, Iwona Damps-Konstańska, Dominika Szalewska, Piotr Janowiak, and Ewa Jassem
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value-based healthcare ,value-based integrated care ,outcome measures ,Medicine - Abstract
Healthcare effectiveness measurement and value in health have been common topics in public health literature since 2006 when value-based healthcare (VBHC) was first defined by Porter and Teisberg. The aim of this study was to identify the barriers and challenges related to the implementation of VBHC solutions in the example of Poland. A case presentation was used as a method. The national integrated care programs (KOS-Infarction, POZ-Plus, and comprehensive treatment of chronic wounds) were used to present general challenges, along with the Integrated Care Model (ICM) for patients with advanced chronic obstructive pulmonary disease (COPD), to determine specific difficulties. ICM has been operating since 2012 in Gdańsk and gradually adapted the value-based integrated care (VBIC) approach. An analysis of the available data showed that the greatest difficulties related to the implementation of the VBHC and VBIC concepts are a lack of legal and reimbursement solutions, staff shortages, a lack of educational standards for some members of the multidisciplinary team, and insufficient awareness of the role of integrated care. As the level of preparation to implement VBHC policies varies between individual countries, the conclusions drawn from the experience of ICM and other Polish projects may be a valuable voice in discussion.
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- 2023
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13. Please explain what this diagnosis means because I don’t quite understand : Patients seeking medical expertise and support in online dialogue to deconstruct hospital discharge documents
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Kiełkiewicz-Janowiak, Agnieszka and Zabielska, Magdalena
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- 2024
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14. Inhaled opioids for cancer pain relief
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Magdalena Osowicka, MD, PhD, Piotr Janowiak, MD, PhD, Agnieszka Gorzewska, MD, PhD, and Monika Lichodziejewska-Niemierko, MD, PhD
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Medicine - Abstract
Abstract. Despite the many new possibilities, cancer pain treatment is not always effective and often poses a challenge for practitioners. At the end-of-life care, both oral and subcutaneous drug delivery very often are not attainable. The increasing number of patients in terminal stage of chronic diseases forced us to look for the alternative ways of administration of pain treatment. In this context, the potentially rapid onset of action and ease of use make aerosolized drug delivery an attractive option in palliative care settings. The objective of this review was to identify literature on pain relief with inhaled opioids. The evidence suggests that nebulized opioids might be effective in the treatment of pain in various aetiologies; however, randomized controlled studies on nebulization therapy for cancer pain are lacking.
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- 2022
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15. Teamwork and Motivation to Leave the Teaching Profession: An Exploratory Study
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Amorim Neto, Roque do Carmo, Bursey, Amanda, Janowiak, Drew, Mccarty, Cassandra, and Demeter, Bart
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This study has two goals: (a) to assess the contributions of teamwork and demographics to teachers' motivation to leave the profession and (b) to identify the actions teachers believe they and their principals should take to foster teamwork. A sample of 322 U.S. public school teachers participated. Grade level was found to predict teachers' motivation to quit. The roles of principals and teachers in fostering teamwork were also discussed.
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- 2018
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16. Involvement of homocastasterone, salicylic and abscisic acids in the regulation of drought and freezing tolerance in doubled haploid lines of winter barley
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Malaga, Sabina, Janeczko, Anna, Janowiak, Franciszek, Waligórski, Piotr, Oklestkova, Jana, Dubas, Ewa, Krzewska, Monika, Nowicka, Anna, Surówka, Ewa, Rapacz, Marcin, Wójcik-Jagła, Magdalena, Kopeć, Przemysław, Hura, Tomasz, Ostrowska, Agnieszka, Kaczanowska, Katarzyna, and Żur, Iwona
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- 2020
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17. Lessons from the Street: An Introduction to Drug Education
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Janowiak, John
- Abstract
The instructional approach used in this teaching idea involves high-level cognitive and affective learning rather than passive learning through lecture, which often is the traditional, and ineffective, approach for students being educated about drugs. Objectives: At the conclusion of this drug education teaching strategy, students will be able to: (1) form opinions based on fact, (2) draw logical conclusions regarding legal and illegal drugs of abuse, (3) categorize drug samples into pharmacological groups, and (4) discuss the laws, availability and abuse of licit and illicit drugs. Target Audience: Middle school and high school students. (Contains 2 tables and 2 figures.)
- Published
- 2009
18. Empowering patients: simplifying discharge instructions
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Charisma DeSai, Keri Janowiak, Beatrice Secheli, Eleanor Phelps, Sam McDonald, Gary Reed, and Andra Blomkalns
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Medicine (General) ,R5-920 - Published
- 2021
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19. Strategies for laboratory professionals to drive laboratory stewardship
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Terra E. White, Wesley B. Wong, Diane Janowiak, and Lee H. Hilborne
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Clinical laboratory ,Laboratory stewardship ,Quality of health care ,Change management ,Patient care ,Leadership ,Medicine (General) ,R5-920 ,Chemistry ,QD1-999 - Abstract
Appropriate laboratory testing is critical in today's healthcare environment that aims to improve patient care while reducing cost. In recent years, laboratory stewardship has emerged as a strategy for assuring quality in laboratory medicine with the goal of providing the right test, for the right patient, at the right time. Implementing a laboratory stewardship program now presents a valuable opportunity for laboratory professionals to exercise leadership within health systems and to drive change toward realizing aims in healthcare. The proposed framework for program implementation includes 5 key elements: 1) a clear vision and organizational alignment; 2) appropriate skills for program execution and management; 3) resources to support the program; 4) incentives to motivate participation; and, 5) a plan of action that articulates program objectives and metrics. This framework builds upon principles of change management, with emphasis on engagement with clinical and administrative stakeholders and the use of clinical data as the basis for change. These strategies enable laboratory professionals to cultivate organizational support for improving laboratory use and take a leading role in providing high-quality patient care.
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- 2021
- Full Text
- View/download PDF
20. Adaptation strategies and approaches for forested watersheds
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P. Danielle Shannon, Christopher W. Swanston, Maria K. Janowiak, Stephen D. Handler, Kristen M. Schmitt, Leslie A. Brandt, Patricia R. Butler-Leopold, and Todd Ontl
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Meteorology. Climatology ,QC851-999 ,Social sciences (General) ,H1-99 - Abstract
Intentional climate adaptation planning for ecosystems has become a necessary part of the job for natural resource managers and natural resource professionals in this era of non-stationarity. One of the major challenges in adapting ecosystems to climate change is in the translation of broad adaptation concepts to specific, tangible actions. Addressing management goals and values while considering the long-term risks associated with local climate change can make forested watershed management plans more robust to uncertainty and changing conditions. We provide a menu of tiered adaptation strategies, which we developed with a focus on forests of the Midwest and Northeastern U.S., as part of a flexible framework to support the integration of climate change considerations into forested watershed management and conservation activities. This menu encapsulates ideas from the literature into statements that signify climate adaptation intention and provide examples of associated tactics to help ground the concepts in specific actions. Finally, we describe two demonstration projects, shared through the Northern Institute of Applied Climate Science’s Climate Change Response Framework, that have used this Forested Watershed Adaptation Menu and Adaptation Workbook in project-level planning. Keywords: Climate change, Adaptation, Water resources, Forest management, Hydrology, Infrastructure
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- 2019
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21. Adaptation Strategies and Approaches for Managing Fire in a Changing Climate
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Martha Sample, Andrea E. Thode, Courtney Peterson, Michael R. Gallagher, William Flatley, Megan Friggens, Alexander Evans, Rachel Loehman, Shaula Hedwall, Leslie Brandt, Maria Janowiak, and Christopher Swanston
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climate adaptation ,wildfire ,prescribed fire ,fuel treatments ,adaptive management ,restoration ,Science - Abstract
As the effects of climate change accumulate and intensify, resource managers juggle existing goals and new mandates to operationalize adaptation. Fire managers contend with the direct effects of climate change on resources in addition to climate-induced disruptions to fire regimes and subsequent ecosystem effects. In systems stressed by warming and drying, increased fire activity amplifies the pace of change and scale of severe disturbance events, heightening the urgency for management action. Fire managers are asked to integrate information on climate impacts with their professional expertise to determine how to achieve management objectives in a changing climate with altered fire regimes. This is a difficult task, and managers need support as they incorporate climate adaptation into planning and operations. We present a list of adaptation strategies and approaches specific to fire and climate based on co-produced knowledge from a science–management partnership and pilot-tested in a two-day workshop with natural resource managers and regional stakeholders. This “menu” is a flexible and useful tool for fire managers who need to connect the dots between fire ecology, climate science, adaptation intent, and management implementation. It was created and tested as part of an adaptation framework used widely across the United States and should be applicable and useful in many fire-prone forest ecosystems.
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- 2022
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22. Secondary Oral Cancer after Systemic Treatment of Hematological Malignancies and Oral GVHD: A Systematic Review
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Aleksandra Janowiak-Majeranowska, Jakub Osowski, Bogusław Mikaszewski, and Alan Majeranowski
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oral cancer ,hematological treatment ,hematopoietic cell transplant ,graft-versus-host disease ,Neoplasms. Tumors. Oncology. Including cancer and carcinogens ,RC254-282 - Abstract
(1) Purpose: In this article, the authors decided to systematically review the available literature to identify potential correlations regarding secondary oral carcinoma occurring after hematological systemic treatment and oral chronic graft-versus-host disease. (2) Methods: Medline (PubMed) and Scopus (Elsevier) databases were searched, including articles from the years 2002–2022. The 33 unique results were assessed by a PRISMA flowchart, and we rejected 24 papers and included 9 articles in the review. (3) Results: The majority of patients suffered from the oral form of chronic graft-versus-host disease before the diagnosis of oral malignancy. Two common cancer sites were the tongue and buccal mucosa. The exact percentage of secondary oral carcinoma after hematopoietic stem cell transplantation could not be estimated due to a lack of data. (4) Conclusions: Every physician taking part in the follow-up of patients after hematological treatment should be aware of the possibility of secondary neoplastic disease in the oral cavity, especially in patients with oral graft-versus-host disease. Proper follow-up protocols and monitoring are needed in this patient group as the cause of these cancers appears to be multifactorial.
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- 2022
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23. Regarding chronic graft-versus-host disease in children and adolescents with thalassemia after hematopoietic stem cell transplantation
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Janowiak–Majeranowska, Aleksandra and Majeranowski, Alan
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- 2021
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24. Stroke heralding granulomatosis with polyangiitis.
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Janowiak, Piotr, Gorzewska, Agnieszka, Szade, Jolanta, Bednarska, Magdalena, Jassem, Jacek, and Jassem, Ewa
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- 2024
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25. Glutathione provides antioxidative defence and promotes microspore-derived embryo development in isolated microspore cultures of triticale (× Triticosecale Wittm.)
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Żur, Iwona, Dubas, Ewa, Krzewska, Monika, Zieliński, Kamil, Fodor, Jozsef, and Janowiak, Franciszek
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- 2019
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26. Teaching Methods in Nutrition: Free Radicals, Antioxidants, and Human Disease.
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Janowiak, John J.
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This article presents a teaching methodology for free radical theory and discusses the role of antioxidants in human health. Free radicals are a normal byproduct of respiration, which allows the body to use oxygen, liberate energy, and dispose of harmful substances. The body's antioxidants and nutritional antioxidants quench most of the free radicals produced. Free radicals drain the body's molecular system of energy by stealing energy in the form of electrons, a process which manifests itself in aging. Growing evidence indicates that this process can be prevented or delayed by dietary changes, such as reduction in fat intake and increased consumption of fruits, grains, and vegetables as well as increased intake of dietary antioxidants, such as vitamin E. Teaching about antioxidant nutrients can be enhanced by renting a cartoon video with a scene from the television cartoon "Mighty Mouse" and showing the class a scene where Mighty Mouse transforms into a super-mouse by consuming nutrients/vitamins and asking appropriate questions. Other effective teaching techniques include showing a transparency on the levels of organization in nature or on a simplified model of atomic structure; explaining the dangers of free radicals to students; asking students to list the fruits and vegetables recently consumed and focusing on including more of these in their diet; and explaining the benefits of eating fresh fruits and vegetables to students. (Contains 21 references.) (CK)
- Published
- 1996
27. An Essay on AIDS Education: The Mythology of Casual Contact.
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Janowiak, John J.
- Abstract
Given the ambiguities and serious consequences of the Human Immunodeficiency Virus (HIV), health professionals must not over simplify HIV transmission. An alarming paradox underlies HIV infection: a preventable disease rooted in human intimacy is reaching pandemic proportions. Well-publicized instances in which persons with AIDS have been shunned attest to concerns regarding HIV transmission. Recent surveys show that significant percentages of respondents believe that AIDS can be passed through casual contact. Although this may be due to some people's lack of authoritative information on AIDS and HIV, research on illness suggests that people tend to group contagious diseases like colds, chicken pox, and AIDS under one category; thus they apply a generic concept to any disease that falls into that category. Although no case of AIDS spread by casual contact has been reported, scientists have not declared such a happenstance as utterly impossible, only as highly improbable. The history, too, of the disease hampers clear thought. Since many people initially associated AIDS with specific populations, those with the disease have been stigmatized. Therefore, efforts to reduce irrational fears and the stigma surrounding AIDS should address concerns about contracting AIDS as well, and also should confront individual prejudices. Contains 14 references. (RJM)
- Published
- 1994
28. The impact of intravenous dobutamine on spirometry with bronchodilator test
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Jan Romantowski, Piotr Janowiak, Elzbieta Wabich, and Krzysztof Kuziemski
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COPD ,Pulmonary function tests ,Heart failure ,Vasopressor ,Bronchodilator ,Diseases of the respiratory system ,RC705-779 - Published
- 2020
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29. Outcomes in CME/CPD - Special Collection Standardising Outcomes Assessment: Demonstrating the Power of Comparative Outcomes Data
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Wendy Cerenzia, Desirae Janowiak, Richie Castles, Annette Triebel, Scott Williams, and Megan Becker
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standardised outcomes evaluation ,aggregate outcomes data ,comparative outcomes data ,outcomes data ,cme comparative outcomes data ,standardised outcomes evaluation tool ,cme evaluation ,Special aspects of education ,LC8-6691 ,Medicine (General) ,R5-920 - Abstract
One challenge in medical education is the inability to compare and aggregate outcomes data across continuing educational activities due to variations in evaluation tools, data collection approaches and reporting. To address this challenge, Gilead collaborated with CE Outcomes to develop, pilot, and implement a standardized outcomes evaluation across Gilead directed medical education activities around the world. Development of the standardized tool occurred during late 2018, with Gilead stakeholders invited to provide input on the questions and structure of the evaluation form. Once input was captured, a draft evaluation tool was developed and circulated for feedback. Questions were created to collect 1) participant demographic characteristics 2)data on planned changes to practice, key learnings and anticipated barriers, and 3) learner satisfaction with content and perceived achievement of learning objectives. The evaluation tool was piloted in H1 2019 across 7 medical education activities. Revisions based on pilot feedback were incorporated. The evaluation tool was broadly released during H2 2019 and data were collected from over 30 educational activities. By the end of 2019, it was possible to compare outcomes results from individual activities and aggregate data to demonstrate overall educational reach and impact. Continuing education activities provide valuable up-to-date information to clinicians with the goal of improving patient care. While often challenging to highlight the impact of education due to variations in outcomes, this standardized approach establishes a method to collect meaningful outcomes data that demonstrates the collective impact of continuing education and allows for comparison across individual activities.
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- 2020
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30. Theoretical Foundations of Yoga Meditation: A Contribution to Self-Actualization and Stress Management.
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Janowiak, John J.
- Abstract
Recent evidence purporting that stress contributes to the development of disorders ranging from depression to cancer to general immunological dysfunction suggests that a concise understanding of stress and stress management techniques is needed in order to develop efficacious interventions. What is needed is an effective, easy-to-learn technique that promotes self-growth while reducing stress. Meditation has been acknowledged as a technique that may fulfill the requirements. Current research on meditation has begun to emphasize the importance of individual differences in cognitive analysis of stress and stress management. In recent years, a number of investigators have reported data indicating profound physiological changes resulting from the practice of meditation. Meditation appears to have several distinct advantages as an aid to personal change. It is a natural and easily learned technique that requires only occasional supervision, which therefore has potential for implementation within the stress management curriculum for college students. The goals of meditation appear to be theoretically similar to Maslow's model of the self-actualized person. While research has indicated a positive relationship between self-actualization and meditation, several methodological problems have been expressed in that research and must be resolved before adequate conclusions can be reached. Since studies report that practitioners of meditation have gained increased emotional stability and reductions of stress as benefits, it may be appropriate to include the instruction of meditation within health education curricula at the university level. (NB)
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- 1993
31. Gender specification of Polish nouns naming people: language system and public debate arguments
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Agnieszka Kiełkiewicz-Janowiak
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feminization ,gender morphology ,Polish ,inclusive language ,public debate ,gender policy ,Philology. Linguistics ,P1-1091 - Abstract
Changes in language practices take place against a backdrop of social pressures for greater gender equality. The topic of the current paper concerns the grammatical and social complexities of a language reform for gender fair representation in the Polish context. The “socially-motivated” language reform, which aims to enhance social equality, is underpinned but also challenged by the language systemon the one hand and by public debate on the other. Therefore, grammatical constraints afforded by the language system need to be investigated in the context of the social attitudes to gender relations in Poland as well as attitudes to the proposed linguistic innovations. It is our aim here to reflect upon the current social debate about the process of ongoing language change, more specifically to consider the relevant linguistic and social arguments. These arguments used are discussed, as revealed in a close analysis of a range of texts of varying genre, social reach and significance, written as a reaction to usage dilemmas often faced by the speakers. The texts were collected between January 2014 and November 2019. The paper concludes with suggestions of the best policy to deal with a highly controversial socio-linguistic issue.
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- 2019
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32. Dosimetrically administered nebulized morphine for breathlessness in very severe chronic obstructive pulmonary disease: a randomized, controlled trial
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Piotr Janowiak, Małgorzata Krajnik, Zygmunt Podolec, Tomasz Bandurski, Iwona Damps-Konstańska, Piotr Sobański, David C. Currow, and Ewa Jassem
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Diseases of the respiratory system ,RC705-779 - Abstract
Abstract Background Systemic morphine has evidence to support its use for reducing breathlessness in patients with severe chronic obstructive pulmonary disease (COPD). The effectiveness of the nebulized route, however, has not yet been confirmed. Recent studies have shown that opioid receptors are localized within epithelium of human trachea and large bronchi, a target site for a dosimetric nebulizer. The aim of this study was to compare any clinical or statistical differences in breathlessness intensity between nebulized 2.0% morphine and 0,9% NaCl in patients with very severe COPD. Methods The study was a double-blind, controlled, cross-over trial. Participants received morphine or NaCl during two 4-day periods. Sequence of periods was randomized. The primary outcome measure was reduction of breathlessness intensity now by ≥20 mm using a 100 mm visual analogue scale (VAS) at baseline, 15, 30, 60, 120, 180 and 240 min after daily administration, during normal activities. Results Ten of 11 patients included completed the study protocol. All patients experienced clinically and statistically significant (p
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- 2017
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33. Extracorporeal Life Support Organization Registry International Report 2022: 100,000 Survivors
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Tonna, Joseph E., Boonstra, Philip S., MacLaren, Graeme, Paden, Matthew, Brodie, Daniel, Anders, Marc, Hoskote, Aparna, Ramanathan, Kollengode, Hyslop, Rob, Fanning, Jeffrey J., Rycus, Peter, Stead, Christine, Barrett, Nicholas A., Mueller, Thomas, Gómez, Rene D., Malhotra Kapoor, Poonam, Fraser, John F., Bartlett, Robert H., Alexander, Peta M.A., Barbaro, Ryan P., Abbasi, Adeel, Said Abdalmohsen, Ahmad, Abdelbary, Akram M., Abecasis, Francisco, Abel, Peter, Abu-Omar, Yasir, Adams, Douglas R, Manuel Africano, Juan, Aganga, Devon, Agati, Salvatore, Agerstrand, Cara, Aguillon, Mario V., Akers, Crystal S., Akhtarekhavari, Julia, Alazzam, Mohammad Izzat Salah, Albert, Martin, Alberti, Angela, Al-Fares, Abdulrahman A., Alfoudri, Huda, Allaert, Silvie, Allbert, Keesha N., Allen, Christopher T., Lescano Alva, Miguel Ángel, Alwardt, Cory M., Amigoni, Angela, Anandamurthy, Balaram, Anastasiadis, Kyriakos, Anders, Nicholas R., Anderson, Scott A., Anderson, Patricia L., Andrijević, Ana, Annoni, Alice, Anselmi, Michael, Anstey, James R., Antonini, Marta V., Antonitsis, Polychronis, Stein Araujo, Tays, Arcalas, Rhodney, Areinamo, Igor, Martin Arias, Anibal, Armijo-Garcia, Veronica, Aronsky, Vladimir, Arora, Lovkesh, Arora, Madhur, Leigh Aspenleiter, Marit, Atik, Fernando A., AugustGeorg Auzinger, Erin Colleen, Azzam, Ismail, Bacchetta, Matthew, Bak, Erica I., Balcells, Joan, Sánchez Ballesteros, Jesús, Banjac, Igor S., Barbaria, Jacqueline M., Barrigoto, Cleide L., Bass, Stephanie D., Batranović, Uroš, Bauer, Matthew H., Fernando Bautista, Diego, Beck, Robert M., Giraldo Bejarano, Estefania, Belohlavek, Jan, Bembea, Melania M., Benes, Jan, Benharash, Peyman, Benish, Lynne A., Bennett, Suzanne, Bento, Luís F.N., Bermudez, Christian A., Bertini, Pietro, Best, Derek, Bharat, Ankit, Bhutta, Omar J., Bizzell, Samantha J., Blakeman, Stephanie A., Blanco-Schweizer, Pablo, Blanton, Jessica K., Blood, Peggy S., Bohlmann, Allison S., Kyle Bohman, John, Bombino, Michela, Kathleen Bonadonna, Desiree, Bond, Ashley, Borgmann, Kristina M., Bourgoin, Pierre, Boville, Brian M., Boza, Raquel, Brady, Heather L., Brady, Alison, Braunlich, Jessica M., Bridges, Brian C., Brinkley, Karen K., Brookshire, Robert S., Brozzi Nicole Brueggemann, Nicolas A., Buckley, Dwight P., Buckley, Klayton, Budhani, Irfan B., Bukamal, Nazar, Burgos, Lucrecia M, Burša, Filip, Busby, Landon K., Buscher, Hergen, Butler, Menoly, Butt, Warwick W., Byrnes, Jonathan W., Calaritis, Christos, Caldwell, Lisa R., Calligaro, Gregory L., Campbell, Patrick T., Camporota, Luigi, Fernando Caneo, Luiz, Jovo Carapic, Vladimir, Carrasco-Carrasco, Cristina, Ivan Carrizo, Nestor, Carrow, Heidi, Carton, Edmund G., Casabella, Christian, Gomez Casal, Vanesa, Casey, Francis L., Castillo, Andres, Castleberry, Anthony W., Alexandros Cavayas, Yiorgos, Cerqua, Karey, Ming Chan, Kai Man ChanWai, Brian Chapman, Jason, Brahma Chari, Hari, Cheifetz, Omair ChaudharyIra M., Chen, Robin H.S, Chen, Weiting, Cheung, Eva W., Cheung, Anson, Chico, Juan I., Chiletti, Roberto, Jin Cho, Hwa, Cholette, Jill M., Christensen, Steffen, Chui, Betty S., Circelli, Alessandro, Clement, Katherine C., Cleuziou, Julie, Clouse, Brian, Cole, Gwendolen, Coles, Garrett M., Collins, Monika F., Collins, Monika F., Connelly, James, Conrad, Steven A., Cook, Marlene, Copeland, Hannah, Copus, Scott C., Cox, Charles S., Craig, Lynne K., Crain, Natasha, Cremonese, Ricardo V., Criswell, Emily A., Cross, Lisa M., Crowley, Moira A., Crowley, Jerome C., Cruz, Leonora, Cypel, Marcelo, Czarnik, Tomasz, Czuczwa, Miroslaw E., Sica da Rocha, Taís, Daddow, Samuel, Dali, Dante C., Dalton, Heidi J., Daly, Kathleen J.R., Damuth, Emily, Daniel, Dennis A., Daniel IV, John M., Daniel, Josiane M., Danis, Max D., Danko, Melissa E., Rodrigues Dantas, Joao Alberto, Daoust, Isabelle, Dauwe, Dieter F., Davidson, Mark, Davis, Joel C., Davis, Mitchell, D’Cunha, Jonathan, de Arruda Bravim, Bruno, de BoodeKim T. De La Cruz, Willem P., Gray DeAngelis, Kathryn, Debeuckelaere, Gerdy, Deitemyer, Matthew A., DellaVolpe, Jeffrey, Deneau, Jamie L., DeNino, Walter F., Denmark, Christopher G., Denney, Derek, DeValeria, Patrick A., Dewulf, Petra, Di Nardo, Matteo, DiBardino, Daniel J., DiMartino, Joseph, Dimopoulos, Stavros, Domico, Michele B., Dominy, Meaghan E., Donker, Dirk W., Dresbach, Till, Droogh, Joep M., Dunlap, Tiffany W., Dupon, Allsion, Durham, Lucian A., Durward, Andrew, Dvorak, Anna, Dyett, John F., Dziedzina, Carol L., Eaken, Carmen L., Eaton, Jonathan S., Eberle, Christopher J., Edwards, Linda, Efseviou, Christakis, Eigner, Juliann M., Ahmed Elhamrawi, Hazem, Elhazmi, Alyaa M., Elizondo, Tammy, Ellersick, Beverly L., Emling, Jonathan A., Ernst, Andreas, Pablo Escalante, Juan, Espinoza, Otoniel, Evey, Lee W., Fan, Eddy, Fang, Gary, Faulkner, Gail M., Fauman, Karen R, Ferguson, Niall, Ferreira, Benigno, Fiane, Arnt E., Andrade Fierro, Dario, Martha Filippi, María, Findeisen, Michael C., Finlay, Katie, Finlayson, Gordon, Fischer, Gwenyth A., Fischer, Courtney D., Fischer, William J., Fisher, Caleb M., Fitriasari, Reni, Fitzgerald, Jillian, Fix, Melissa K., Fleming, Sarah B., Flynn, Brigid C., Forst, Beth A., Fortuna, Philip P., Foti, Giuseppe, Fox, Matthew P., Franco, Thais O., David Freeland, C., Fried, Justin A., Friedman, Matthew L., Furlanetto, Beatriz, Fux, Thomas, Gaião, Sérgio, Gale, Michael J., Garcia, Joann Kathleen G., Garcia-Montilla, Romel, Gardner, Eric R., Garg, Meena, Garrison, Lawrence L., Gavrilovic, Srdjan M., Gawda, Ryszard, Geer, Laura W., Gelandt, Elton A., Gelvin, Michael G., Genovese, Bradley M., George, Jeffrey A., George, Timothy J, George, Sangley, Ghimire, Anup, Giani, Marco, Gill, Baljit S., Glikes, Erin, Golecki, Michael, Gongora, Enrique, Govener, Sara, Graf, Amanda, Grasselli, Giacomo, Gray, Brian W., Greenlee, Joseph A., Gregoric, Igor D., Gregory, Melinda, Grins, Edgars, Volker Groesdonk, Heinrich, Group, Kimberly F., Guarracino, Fabio, Joy Guidi-Solloway, Alexandra, Gunn, Tyler M., Guru, Pramod K, Haddle, John C., Haft, Jonathan W., Haisz, Emma, Hall, Julie L., Hall, Cameron, Hamaguchi, Jun, Hammond, Terese C., Han, Peggy K., Hardison, Daphne C., Harischandra, Dickwelle T., Hart, Shaun M., Harting, Matthew T., Hartley, Louise, Harvey, Chris J., Hasan, Zubair, Fawzy Hassan, Ibrahim, Hastings, Jennifer R., Hatcher, Renee’, Hatton, Kevin W., Haught, Christopher K., Awori Hayanga, Jeremiah, Peter Haydon, Timothy, Healy, Aaron H., Heard, Micheal L., Heather, Beth M., Hendrix, Rik H.J., Hennig, Felix, Hermens, Greet HermansJeannine A.J., Hernandez, Deborah A., Hernandez-Montfort, Jaime, Herrera, Guillermo, Hickman, Keri, Hittel, Ashley, Hobbs, Crystal, Hoffman, Jordan R.H., Hollinger, Laura E., Homishak, Michael, Horigoshi, Nelson K., Hoshino, Kota, Huang, Shu-Chien, Huenges, Katharina, Hussey, Alexander D., Hyslop, Robert W., Ihle, Rayan E., Ingemansson, Ola, Ivulich, Daniel, Jackson, Amanda L., Garcia Jacques, Rogelio, Jain, Harsh, Jakobs, Sharon M., Jan, Robert, Janowiak, Lisa M., Jara, Claire B., Jarden, Angela M., Jarzembowski, Jamie L., Jaudon, Andrew, Kishore Jayanthi, Venkata Krishna, Jennings, Joseph A., Jeong, Inseok, Meza Jiménez, Rafael, Jimenez-Rodriguez, Gian M., Joachim, Sabrina, Joelsons, Daniel, Johnson, Caroline A., Johnson, Andrea L., Jones, Jeffry H., Joseph, Mark, Joseph, Sunimol, Joshi, Raja, Joyce, Christopher J., Seung Jung, Jae, Carone Junior, José, Kallas, Harry J., KamerkarPilje Kang, Asavari, Kar, Biswajit, Karapanagiotidis, Georgios T., Kattan, Javier, Kaufman, David A., Kawauchi, Akira, Keene, Sarah D., Keller, Norma M., Keller, Roberta, Kelley, Emily W., Kelley, Kellie, Kelly-Geyer, Janet F., Kenderessy, Peter, Kenny, Laura E., Keshavjee, Shaf, Kessel, D., Kessler, Heather, Keuler, Suzanne, Khicha, Sanjay, Wan Kim, Do, Kim, Richard Y., Maxwell Kime, Aaron, Kincade, Robert C., Kipfmueller, Florian, Kirk, Douglas A., Klein, Liviu, Knapp, Randall S., Knapp, Randall S., Kneyber, Martin C.J., Knowles, Andrea L., Koch, Jillian M., Koepke, Stephanie, Kogelmann, Klaus M., Elzo Kraemer, Carlos, Krauklis, Amanda, Krumroy, Samantha L., Kumar, Madhan, Kumar, Arun, Kumpf, Matthias E, Kyle, Kimberly, Laffin, Anna, Kees Lagrand, Wim, Lahiji, Parshawn A., Keung Lai, Peter Chi, Ka Lai, Cally Ho, Danielle Laird, Amanda, Landsberg, Michelle LaMarreDavid M., Lanmueller, Pia, Oude Lansink-Hartgring, Annemieke, Beth Larson, Sharon, Laufenberg, De’Ann M., Lavana, Jayshree, Layne, Tracie L., John Lazar, Michael, Ledoux, Matthew R., Lee, Raymond C., Leek, Thomas M., Lequier, Laurance, Lesbekov, Timur, Leslie, Robert, Anne Leung, Kit Hung, Lillie, Jon, Phang Lim, Yeong, Lim, Sang-Hyun, Lin, Ling, Lindsey, Thomas, Ho Ling, Steven Kin, Lingle, Kaitlyn J., Lipes, Jed, Liu, Songqiao, Llevadias, Judit, Lomas, Erin A., Longenecker, Robert D., Lorusso, Roberto, Ann Low, Tracy, Steven Lubinsky, Anthony, Lucas, Matthias LubnowMark T., Lucchini, Alberto, Luze, Lisa E., Lynch, William R., Manoj, M.C., Maas, Jacinta J., MacNamara, Vanessa, Madden, Jesse L., Maimone, Justin, Malhotra, Rajiv, Malone, Matthew P., Mangukia, Chirantan, Manzur-Sandoval, Daniel, Maráczi, Veronika, Marinaro, Jonathan L., Marinucci, Christina R., Marshall, Tammy, Martin, Mark, Marwali, Eva M., Maslach-Hubbard, Anna, Matijašević, Jovan, Mattke, Adrian, Mattucci, Joseph, Maul, Timothy M., Maybauer, Marc O., Mayette, Michael, Mayville, Joni R., McAllister, Catherine, McBride, Martha W., Scott McCaul, David, McClelland, Samantha L.S., Gregory McCloskey, Colin, McGregor, Randy, McKamie, Wesley A., McKee, Andrew D., McMahon, Chelsea M., McMullin, Kaye, McNicol, Jane, McNulty, John P., McRae, Thomas, Meade, Maureen E., Meersseman, Philippe, Mekeirele, Michael, Ito Mendes, Elisa, Menon, Anuradha P., Meyer, Jason P., Meyers, Jourdan E., Meyns, Bart, Mignone, John L., Miller, Brittany D., Miller, Malcolm G.A., Miller, Deborah, Mintak, Renee, Minter, Sarah M., Reis Miranda, Dinis, Mirza, Farrukh, Mishkin, Joseph D., Modelewski, Paul, Mohan, Rajeev C., Hui Mok, Yee, Money, Dustin, Monteagudo, Julie, Moores, Russell R., Moran, Patrick, Morelock, Shawn, Moreno, Marsha R., Blanco Morillo, Juan, Morrison, Tracy, Morton, John M., Morton, Brenda, Moscatelli, Andrea, Mosier, Jarrod M., Muellenbach, Ralf M., Mueller, Andreas, Mueller, Dale, Musca, Steven C., Nagpal, Dave, Najaf, Tasnim, Narasimhan, Mangala, Nater, Melissa, Natividad, Zynthia, Nedeljkov, Djordje, Nelson, Bryan D., Newman, Sally F., Newton, Debra E., Neyman, Jonathan L., George Ng, Wing Yiu, Nicholson, Meghan C., Nicolaas, Christine, Nix, Charlie, Nkwantabisa, Raymond, Nolan, Shirley, Norese, Mariano, Norton, Bridget M., Norton, Bridget M., O’Brien, Serena G., O’Callaghan, Maura, Oishi, Peter, O’Leary, Tony D., Olia, Salim E., O’Meara, Carlisle, Oppel, Emily E., Arias Ortiz, Julian, Oza, Pranay L., Ozment, Caroline P., Pacific, Marjorie, Pálizas, Fernando, Palmer, David, Paoletti, Luca, Pardo, Diego H., Paredes, Pablo, Patel, Thomas PasgaardMrunal G., Patel, Sandeep M., Patel, Vijay S., Patel, Brijesh V., PatelDrisya Paul, Sameer, Pawale, Amit A., Pearson, Nicole M., Renee Pearson, Crystal, Peek, Giles J., Pellecchia, Crescens M., Pellegrino, Vincent, Peperstraete, Harlinde, Perkins, Rebecca L., Perkins, Brandon, Peterec, Steven, Peterman, Claire, Phillips, Cooper W., Piekutowski, Richard R., Pilan, María L., Luisa Pilan, Maria, Mark Pincus, Jason, Pino, Melissa, Plambeck, Robert W., Plisco, Michael S., Plumley, Donald A., Plunkett, Mark D., Poffo, Robinson, Poh, Pei-Fen, Polito, Angelo, Pollema, Travis L, Pozzi, Matteo, Pozzi, Matteo, Pranikoff, Thomas, Prekker, Matthew E., Prossen, Erik F., Puligandla, Pramod S., Puslecki, Mateusz, Raheel Qureshi, Muhammad, Emilia Rabanal, Lily, Abdulhamid Rabie, Ahmed, Rackley, Craig R., Radovancevic, Rajko, Raes, Matthias, Allen Raff, Lauren Desiree, Rahban, Youssef, Raimer, Patricia L., Rajbanshi, Bijoy G., Ramanan, Raj, Rambaud, Jerome, Ramírez-Arce, Jorge A., Simões Ramos, Ana Carolina, Rao, Suresh G., Rector, Raymond, Redfors, Bengt, Regmi, Ashim, Alejandro Rey, Jose, Miguel Ribeiro, Joao, Richards, Chelsea E, Joan Richardson, C., Riddle, Christy C., Riera, Jordi, Ripardo, Marina, Rivas, Fernando M., Roan, Ronald M., Robertson, Elizabeth, Robinson, Megan, Röder, Daniel, Rodrigus, Inez E.R., Paul Roeleveld, Peter, Romano, Jennifer C., Rona, Roberto, Ann Rosenberg, Carol, Rosenow, Felix, Rowe, Robert J., Rower, Katy E., Rudolph, Kristina L., Fernando Rueda, Luis, Ruf, Bettina, Russell, Hyde M., Russell, Nichole, Ryan, Kathleen, Saberi, Asif A., Said, Ahmed S., Sailor, Caitlin, Sakal, Angela, Lujan Salas, Gisela, Salazar, Leonardo, Saleem, Kashif, Samoukovic, Gordan, Sanchez, Pablo G., Marie Santiago, Lian, Sargin, Murat, Miguel Sassine, Assad, Satou, Nancy L., Saunders, Paul C., Schachinger, Scott, Schaible, Thomas, Schellongowski, Peter, Schlager, Gerald W., Schmid, Christof, Schmitt, Joachim, Schnell, LeeAndra, Schnur, Janos, Schroeder, Lukas, Schubach, Scott, Schuetz, Michael T., Schwartz, Gary S., Schwarz, Patricia, Scriven, Nicole M., Seabrook, Ruth B., Seefeldt, Cassandra, Seelhammer, Troy G., Segura-Matute, Susana, Sen, Ayan, Adrian Seoane, Leonardo, Shaffer, Jamie, Shafi, Bilal M., Shambley, Shannon, Shankar, Shyam, Shapland, Amanda, Sharng, Yih, Shavelle, David, Sheldrake, Jayne, Mohan Shetty, Rajesh, Shiber, Joseph R., Shimzu, Naoki, Lou Short, Billie, Sichting, Kay A., Sidehamer, Keith E., Siebenaler, Teka, Silvestry, Scott C., Sinclair, Jennifer T, Sinclair, Andrew, Singh, Aalok R., Singh, Gurmeet, Skinner, Sean C., Smart, Alexandra, Smith, Reanna M., Smith, Adam, Smith, Karen, Sommer-Candelario, Sherri, Song, Seunghwan, Sorensen, Gro, Sousa, Eduardo, Sower, Christopher T., Spadea, Nicholas V, Spangle, April, Speicher, David G., Spieth, Peter M., Srivastava, Ankur, Srivastava, Neeraj, Stahl, Mark, Stallkamp, Eric D., Stanley, Vanessa J., Starr, Joanne P., Staudinger, Thomas, Stevens, Berkeley E., Stevens, Kimberly, Stocker, Christian, Strickland, Richard, Suarez, Erik E., Kumar Subramanian, Rakesh, Sudakevych, Serhii, Summerall, Charlene, Sundararajan, Santosh, Susupaus, Attapoom, Suzuki, Hiroyuki, Sweberg, Todd, Sydzyik, Troy, Anh Ta, Tuan, Tagliari, Luciana, Tanaka, Hiroyuki, Tanski, Christopher T., Tasset, Mark, Taylor, Donna M., Teman, Nicholas R., Ramesh Thangaraj, Paul, Thiagarajan, Ravi R., Thiruchelvam, Timothy, Thomas, James A., Thomas, Owain D., Thompson, Shaun L., Thomson, David A., Thukaram, Roopa, Todd, Mark L., Toeg, Hadi, Torres, Silvio F., Trautner, Simon, Trombino, Terry, Tuazon, Divina M., Tuel, Julie, Tukacs, Monika, Turner, April N., Tyree, Melissa M., Uchiyama, Makoto, Vaijyanath, Prashant, van den Brule, Judith M.D., van Dyck, Marlice A., van Gijlswijk, Mascha, Van Meurs, Krisa P., VanDyck, Tyler J., Vardi, Amir, Vega, Alejandra, Ventetuolo, Corey E., Vera, Magdalena, Vercaemst, Leen, Vets, Philippe, Viamonte, Heather, Vidlund, Mårten, Vitali, Sally H., Vlaa, Alexander P.J., Vuylsteke, Alain, Loon Wan, Kah, Watkins, Reuben, Watson, Pia, Weast, Travis A., Weaver, Karen E., Welkovics, Norbert, Wellner, Heidi L., Wells, Jason C., Welter, Karen, Westpheling, Amber G., Whalen, Lesta D.S., Whebell, Stephen, Wiersema, Ubbo, Wiisanen, Matthew E., Eugene Wilcox, Bradley, Wille, Keith, Jan Will, Ellyne, Wilson, Brock J., Win, April M., Winearls, James R., Wise, Linda J., Witter, Tobias, Ruby Wong, Hoi Mei, Worku, Berhane, Wright, Tina M, Wu, James K., Yalon, Larissa A., Yantosh, Garrett, Yaranov, Dmitry M., Yee, Pat, Yi, Cassia, Yost, Christian C., Young, John, Younger, Katrina, Zaborowski, Steven, Zachmann, Brenda, Zainab, Asma, Zanai, Rosanna, Zhao, Ju, Zhou, Chengbin, and Zinger, Marcia
- Abstract
The Extracorporeal Life Support Organization (ELSO) maintains the world’s largest extracorporeal membrane oxygenation (ECMO) registry by volume, center participation, and international scope. This 2022 ELSO Registry Report describes the program characteristics of ECMO centers, processes of ECMO care, and reported outcomes. Neonates (0–28 days), children (29 days–17 years), and adults (≥18 years) supported with ECMO from 2009 through 2022 and reported to the ELSO Registry were included. This report describes adjunctive therapies, support modes, treatments, complications, and survival outcomes. Data are presented descriptively as counts and percent or median and interquartile range (IQR) by year, group, or level. Missing values were excluded before calculating descriptive statistics. Complications are reported per 1,000 ECMO hours. From 2009 to 2022, 154,568 ECMO runs were entered into the ELSO Registry. Seven hundred and eighty centers submitted data during this time (557 in 2022). Since 2009, the median annual number of adult ECMO runs per center per year increased from 4 to 15, whereas for pediatric and neonatal runs, the rate decreased from 12 to 7. Over 50% of patients were transferred to the reporting ECMO center; 20% of these patients were transported with ECMO. The use of prone positioning before respiratory ECMO increased from 15% (2019) to 44% (2021) for adults during the coronavirus disease-2019 (COVID-19) pandemic. Survival to hospital discharge was greatest at 68.5% for neonatal respiratory support and lowest at 29.5% for ECPR delivered to adults. By 2022, the Registry had enrolled its 200,000th ECMO patient and 100,000th patient discharged alive. Since its inception, the ELSO Registry has helped centers measure and compare outcomes across its member centers and strategies of care. Continued growth and development of the Registry will aim to bolster its utility to patients and centers.
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- 2024
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34. Impact of Ascorbate—Glutathione Cycle Components on the Effectiveness of Embryogenesis Induction in Isolated Microspore Cultures of Barley and Triticale
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Iwona Żur, Przemysław Kopeć, Ewa Surówka, Ewa Dubas, Monika Krzewska, Anna Nowicka, Franciszek Janowiak, Katarzyna Juzoń, Agnieszka Janas, Balázs Barna, and József Fodor
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antioxidant defence ,ascorbate ,glutathione ,microspore embryogenesis ,reactive oxygen species ,Hordeum vulgare ,Therapeutics. Pharmacology ,RM1-950 - Abstract
Enhanced antioxidant defence plays an essential role in plant survival under stress conditions. However, excessive antioxidant activity sometimes suppresses the signal necessary for the initiation of the desired biological reactions. One such example is microspore embryogenesis (ME)—a process of embryo-like structure formation triggered by stress in immature male gametophytes. The study focused on the role of reactive oxygen species and antioxidant defence in triticale (×Triticosecale Wittm.) and barley (Hordeum vulgare L.) microspore reprogramming. ME was induced through various stress treatments of tillers and its effectiveness was analysed in terms of ascorbate and glutathione contents, total activity of low molecular weight antioxidants and activities of glutathione–ascorbate cycle enzymes. The most effective treatment for both species was a combination of low temperature and exogenous application of 0.3 M mannitol, with or without 0.3 mM reduced glutathione. The applied treatments induced genotype-specific defence responses. In triticale, both ascorbate and glutathione were associated with ME induction, though the role of glutathione did not seem to be related to its function as a reducing agent. In barley, effective ME was accompanied by an accumulation of ascorbate and high activity of enzymes regulating its redox status, without direct relation to glutathione content.
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- 2021
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35. Changes in Ethylene, ABA and Sugars Regulate Freezing Tolerance under Low-Temperature Waterlogging in Lolium perenne
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Barbara Jurczyk, Ewa Pociecha, Franciszek Janowiak, Michał Dziurka, Izabela Kościk, and Marcin Rapacz
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ABA ,cold acclimation ,ethylene ,freezing tolerance ,perennial ryegrass ,waterlogging ,Biology (General) ,QH301-705.5 ,Chemistry ,QD1-999 - Abstract
Plant overwintering may be affected in the future by climate change. Low-temperature waterlogging, associated with a predicted increase in rainfall during autumn and winter, can affect freezing tolerance, which is the main component of winter hardiness. The aim of this study was to elucidate the mechanism of change in freezing tolerance caused by low-temperature waterlogging in Lolium perenne, a cool-season grass that is well adapted to a cold climate. The work included: (i) a freezing tolerance test (plant regrowth after freezing); (ii) analysis of plant phytohormones production (abscisic acid [ABA] content and ethylene emission); (iii) measurement of leaf water content and stomatal conductance; (iv) carbohydrate analysis; and (v) analysis of Aco1, ABF2, and FT1 transcript accumulation. Freezing tolerance may be improved as a result of cold waterlogging. The mechanism of this change is reliant on multifaceted actions of phytohormones and carbohydrates, whereas ethylene may counteract ABA signaling. The regulation of senescence processes triggered by concerted action of phytohormones and glucose signaling may be an essential component of this mechanism.
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- 2021
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36. Beyond Planning Tools: Experiential Learning in Climate Adaptation Planning and Practices
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Kristen M. Schmitt, Todd A. Ontl, Stephen D. Handler, Maria K. Janowiak, Leslie A. Brandt, Patricia R. Butler-Leopold, P. Danielle Shannon, Courtney L. Peterson, and Christopher W. Swanston
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climate change ,adaptation planning ,natural resources ,training ,climate framework ,climate-informed management ,Science - Abstract
In the past decade, several dedicated tools have been developed to help natural resources professionals integrate climate science into their planning and implementation; however, it is unclear how often these tools lead to on-the-ground climate adaptation. Here, we describe a training approach that we developed to help managers effectively plan to execute intentional, climate-informed actions. This training approach was developed through the Climate Change Response Framework (CCRF) and uses active and focused work time and peer-to-peer interaction to overcome observed barriers to using adaptation planning tools. We evaluate the effectiveness of this approach by examining participant evaluations and outlining the progress of natural resources projects that have participated in our trainings. We outline a case study that describes how this training approach can lead to place and context-based climate-informed action. Finally, we describe best practices based on our experience for engaging natural resources professionals and helping them increase their comfort with climate-informed planning.
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- 2021
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37. Herbal Additives Substantially Modify Antioxidant Properties and Tocopherol Content of Cold-Pressed Oils
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Kamila Laskoś, Elżbieta Pisulewska, Piotr Waligórski, Franciszek Janowiak, Anna Janeczko, Iwona Sadura, Szymon Polaszczyk, and Ilona Mieczysława Czyczyło-Mysza
- Subjects
oily herbal plants ,macerates ,Salvia officinalis L. ,Thymus vulgaris L. ,Ocimum basilicum L. ,oil cake ,Therapeutics. Pharmacology ,RM1-950 - Abstract
The aim of the study was to examine combinations of base oils and herbal additives with a view to obtaining macerates with improved health benefits. Base oils were cold-pressed from the seeds of black cumin, borage, evening primrose, safflower, walnut, common hazel, and oilseed rape, as well as the flesh of sea-buckthorn fruits. They were then supplemented with herbs, including basil, thyme, and sage, in order to create macerates. Total antioxidant activity and tocopherol level were analyzed in oils, macerates, and oil cakes. Additionally, chemical properties of oil cakes—such as the level of fibre, vitamin C, β-carotene, and lutein—were also examined. Supplementation with herbs caused diversified effects on antioxidant activity and tocopherol level in macerates depending on the base oil, herb, and supplementation method. The obtained results indicate that tocopherol level does not play a decisive role in determining the antioxidant properties of oils, macerates, and oil cakes, suggesting significant involvement of other antioxidants. Among the tested macerates, the most promising one seems to be oilseed rape oil enriched with sage or basil to maximize its health benefits. The study can serve as a starting point for the development and implementation of functional macerates and oil cakes in healthy nutrition.
- Published
- 2021
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38. Accumulation of Silicon and Changes in Water Balance under Drought Stress in Brassica napus var. napus L.
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Diana Saja-Garbarz, Agnieszka Ostrowska, Katarzyna Kaczanowska, and Franciszek Janowiak
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orthosilicic acid ,iron ,canola ,water management ,water deficit ,stress tolerance ,Botany ,QK1-989 - Abstract
The aim of this study was to investigate the accumulation of silicon in oilseed rape and to characterize the changes in chosen water balance parameters in response to drought. The following parameters were estimated: water content, osmotic and water potential, evapotranspiration, stomatal conductance and abscisic acid level under optimal and drought conditions. It was shown that oilseed rape plants accumulate silicon after its supplementation to the soil, both in the case of silicon alone and silicon together with iron. It was revealed that silicon (without iron) helps maintain constant water content under optimal conditions. While no silicon influence on osmotic regulation was observed, a transpiration decrease was detected under optimal conditions after silicon application. Under drought, a reduction in stomatal conductance was observed, but it was similar for all plants. The decrease in leaf water content under drought was accompanied by a significant increase in abscisic acid content in leaves of control plants and those treated with silicon together with iron. To sum up, under certain conditions, silicon is accumulated even in non-accumulator species, such as oilseed rape, and presumably improves water uptake under drought stress.
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- 2021
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39. Comparison of survival by vasoactive-inotropic score in patients receiving veno-arterial extracorporeal life support
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Weeks, Phillip, Dunton, Kelly, Gulbis, Brian, Jumean, Marwan, Janowiak, Lisa, Banjac, Igor, Radovancevic, Rajko, Gregoric, Igor, and Kar, Biswajit
- Abstract
After the initiation of veno-arterial extracorporeal membrane oxygenation (V-A ECMO) for hemodynamic support, patients often require vasopressor and inotropic medications to support their blood pressure and cardiac contractility. The vasoactive-inotropic score (VIS) is a standardized calculation of vasopressor and inotrope equivalence, which uses coefficients for each medication to calculate a total value. This study evaluated the association between the 30-day survival of patients receiving V-A ECMO support and the VIS calculated 24 h after ECMO cannulation (VIS24). This was a single-center, retrospective, observational cohort study. The median VIS24 of the entire cohort was 6.0, and was determined as a cutoff for comparison. Patients with a VIS24 < 6.0 were assigned to a group, and those with a VIS24 ≥ 6.0 were assigned to a second group. Patients with a VIS24 < 6.0 had higher 30-day survival than those with a VIS24 ≥ 6.0 (54.5% vs 41.4%; p= 0.03). The group with a VIS24 < 6.0 also had significantly improved survival to decannulation of ECMO support; however, there was no difference in the survival to hospital discharge. We conducted a secondary analysis of quartiles and determined that individuals with a VIS24 > 11.4 had the lowest survival in the cohort. This finding may help identify patients with the lowest probability of 30-day survival in those receiving V-A ECMO for hemodynamic support.
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- 2023
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40. Vulnerability of forests of the Midwest and Northeast United States to climate change
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Swanston, Chris, Brandt, Leslie A., Janowiak, Maria K., Handler, Stephen D., Butler-Leopold, Patricia, Iverson, Louis, Thompson III, Frank R., Ontl, Todd A., and Shannon, P. Danielle
- Published
- 2017
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41. Multi-model comparison on the effects of climate change on tree species in the eastern U.S.: results from an enhanced niche model and process-based ecosystem and landscape models
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Iverson, Louis R., Thompson, III, Frank R., Matthews, Stephen, Peters, Matthew, Prasad, Anantha, Dijak, William D., Fraser, Jacob, Wang, Wen J., Hanberry, Brice, He, Hong, Janowiak, Maria, Butler, Patricia, Brandt, Leslie, and Swanston, Christopher
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- 2017
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42. Adaptation pathways: ecoregion and land ownership influences on climate adaptation decision-making in forest management
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Ontl, Todd A., Swanston, Chris, Brandt, Leslie A., Butler, Patricia R., D’Amato, Anthony W., Handler, Stephen D., Janowiak, Maria K., and Shannon, P. Danielle
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- 2017
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43. Exogenous Polyamines Only Indirectly Induce Stress Tolerance in Wheat Growing in Hydroponic Culture under Polyethylene Glycol-Induced Osmotic Stress
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Izabela Marcińska, Kinga Dziurka, Piotr Waligórski, Franciszek Janowiak, Edyta Skrzypek, Marzena Warchoł, Katarzyna Juzoń, Kamila Kapłoniak, and Ilona Mieczysława Czyczyło-Mysza
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osmotic stress ,PEG ,polyamines ,fluorescence kinetics ,biochemical factors ,yield ,Science - Abstract
The aim of the present study was to evaluate the effect of osmotic stress caused by polyethylene glycol (PEG) 6000 in hydroponic culture on wheat seedlings of drought-resistant Chinese Spring (CS) and drought-susceptible SQ1 cultivar, and to examine the alleviative role of exogenous polyamines (PAs) applied to the medium. The assessment was based on physiological (chlorophyll a fluorescence kinetics, chlorophyll and water content) as well as biochemical (content of carbohydrates, phenols, proline, salicylic and abscisic acid, activity of low molecular weight antioxidants) parameters, measured after supplementation with PAs (putrescine, spermidine and spermine) on the 3rd, 5th and 7th day of the treatment. The results indicate that PAs ameliorate the effects of stress, indirectly and conditionally inducing stress tolerance of wheat seedlings. In contrast to the susceptible SQ1, the resistant CS cultivar activated its protective mechanisms, adjusting the degree of their activation to the level of the stress, depending on the genetic resources of the plant. Increased accumulation of antioxidants in the resistant CS in response to stress after the application of PAs confirms the hypothesis that PAs are involved in the signaling pathway determining the antioxidative response and the tolerance of wheat plants to drought stress.
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- 2020
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44. Reversible Oxidative Modifications in Myoglobin and Functional Implications
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Mark H. Mannino, Rishi S. Patel, Amanda M. Eccardt, Blythe E. Janowiak, David C. Wood, Fahu He, and Jonathan S. Fisher
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myoglobin ,dityrosine ,ditryptophan ,peroxidase ,protein aggregation ,Therapeutics. Pharmacology ,RM1-950 - Abstract
Myoglobin (Mb), an oxygen-binding heme protein highly expressed in heart and skeletal muscle, has been shown to undergo oxidative modifications on both an inter- and intramolecular level when exposed to hydrogen peroxide (H2O2) in vitro. Here, we show that exposure to H2O2 increases the peroxidase activity of Mb. Reaction of Mb with H2O2 causes covalent binding of heme to the Mb protein (Mb-X), corresponding to an increase in peroxidase activity when ascorbic acid is the reducing co-substrate. Treatment of H2O2-reacted Mb with ascorbic acid reverses the Mb-X crosslink. Reaction with H2O2 causes Mb to form dimers, trimers, and larger molecular weight Mb aggregates, and treatment with ascorbic acid regenerates Mb monomers. Reaction of Mb with H2O2 causes formation of dityrosine crosslinks, though the labile nature of the crosslinks broken by treatment with ascorbic acid suggests that the reversible aggregation of Mb is mediated by crosslinks other than dityrosine. Disappearance of a peptide containing a tryptophan residue when Mb is treated with H2O2 and the peptide’s reappearance after subsequent treatment with ascorbic acid suggest that tryptophan side chains might participate in the labile crosslinking. Taken together, these data suggest that while exposure to H2O2 causes Mb-X formation, increases Mb peroxidase activity, and causes Mb aggregation, these oxidative modifications are reversible by treatment with ascorbic acid. A caveat is that future studies should demonstrate that these and other in vitro findings regarding properties of Mb have relevance in the intracellular milieu, especially in regard to actual concentrations of metMb, H2O2, and ascorbate that would be found in vivo.
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- 2020
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45. Endogenous ABA content in relation to maturation of somatic embryos in Tulipa (L.) ‘Apeldoorn’ cultures
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Maślanka, Małgorzata, Bach, Anna, and Janowiak, Franciszek
- Published
- 2016
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46. Comparative study of radio-frequency and microwave heating for phytosanitary treatment of wood
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Dubey, Manoj K., Janowiak, John, Mack, Ron, Elder, Peggy, and Hoover, Kelli
- Published
- 2016
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47. Impact of soil compaction stress combined with drought or waterlogging on physiological and biochemical markers in two maize hybrids
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Grzesiak, Maciej T., Janowiak, Franciszek, Szczyrek, Piotr, Kaczanowska, Katarzyna, Ostrowska, Agnieszka, Rut, Grzegorz, Hura, Tomasz, Rzepka, Andrzej, and Grzesiak, Stanisław
- Published
- 2016
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48. Investigating Manuka Honey Antibacterial Properties When Incorporated into Cryogel, Hydrogel, and Electrospun Tissue Engineering Scaffolds
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Katherine R. Hixon, Savannah J. Bogner, Gabriela Ronning-Arnesen, Blythe E. Janowiak, and Scott A. Sell
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Manuka honey ,tissue engineering ,scaffolds ,electrospun scaffolds ,hydrogels ,cryogels ,Science ,Chemistry ,QD1-999 ,Inorganic chemistry ,QD146-197 ,General. Including alchemy ,QD1-65 - Abstract
Honey is well-known for its wound healing capability and Manuka honey (MH) contains a unique Manuka factor, providing an additional antibacterial agent. Previously, there has not been a practical way to apply MH to a wound site, which renders treatment for an extended period extremely difficult. Tissue-engineered scaffolds offer an alternative treatment method to standard dressings by providing varying geometries to best treat the specific tissue. MH was incorporated into cryogels, hydrogels, and electrospun scaffolds to assess the effect of scaffold geometry on bacterial clearance and adhesion, as well as cellular adhesion. Electrospun scaffolds exhibited a faster release due to the nanoporous fibrous geometry which led to a larger partial bacterial clearance as compared to the more three-dimensional cryogels (CG) and hydrogels (HG). Similarly, the fast release of MH from the electrospun scaffolds resulted in reduced bacterial adhesion. Overall, the fast MH release of the electrospun scaffolds versus the extended release of the HG and CG scaffolds provides differences in cellular/bacterial adhesion and advantages for both short and long-term applications, respectively. This manuscript provides a comparison of the scaffold pore structures as well as bacterial and cellular properties, providing information regarding the relationship between varying scaffold geometry and MH efficacy.
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- 2019
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49. Alleviation of Osmotic Stress Effects by Exogenous Application of Salicylic or Abscisic Acid on Wheat Seedlings
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Katarzyna Cyganek, Katarzyna Juzoń, Piotr Waligórski, Kinga Dziurka, Michał Dziurka, Maria Filek, Franciszek Janowiak, Maciej T. Grzesiak, Edyta Skrzypek, Ilona Czyczyło-Mysza, Izabela Marcińska, and Stanisław Grzesiak
- Subjects
abscisic acid ,salicylic acid ,hydroponic culture ,osmotic stress ,drought tolerance ,yield ,wheat ,Biology (General) ,QH301-705.5 ,Chemistry ,QD1-999 - Abstract
The aim of the study was to assess the role of salicylic acid (SA) and abscisic acid (ABA) in osmotic stress tolerance of wheat seedlings. This was accomplished by determining the impact of the acids applied exogenously on seedlings grown under osmotic stress in hydroponics. The investigation was unique in its comprehensiveness, examining changes under osmotic stress and other conditions, and testing a number of parameters simultaneously. In both drought susceptible (SQ1) and drought resistant (CS) wheat cultivars, significant physiological and biochemical changes were observed upon the addition of SA (0.05 mM) or ABA (0.1 μM) to solutions containing half-strength Hoagland medium and PEG 6000 (−0.75 MPa). The most noticeable result of supplementing SA or ABA to the medium (PEG + SA and PEG + ABA) was a decrease in the length of leaves and roots in both cultivars. While PEG treatment reduced gas exchange parameters, chlorophyll content in CS, and osmotic potential, and conversely, increased lipid peroxidation, soluble carbohydrates in SQ1, proline content in both cultivars and total antioxidants activity in SQ1, PEG + SA or PEG + ABA did not change the values of these parameters. Furthermore, PEG caused a two-fold increase of endogenous ABA content in SQ1 and a four-fold increase in CS. PEG + ABA increased endogenous ABA only in SQ1, whereas PEG + SA caused a greater increase of ABA content in both cultivars compared to PEG. In PEG-treated plants growing until the harvest, a greater decrease of yield components was observed in SQ1 than in CS. PEG + SA, and particularly PEG + ABA, caused a greater increase of these yield parameters in CS compared to SQ1. In conclusion, SA and ABA ameliorate, particularly in the tolerant wheat cultivar, the harmful effects and after effects of osmotic stress induced by PEG in hydroponics through better osmotic adjustment achieved by an increase in proline and carbohydrate content as well as by an increase in antioxidant activity.
- Published
- 2013
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50. Following Natures Lead: On the Construction of Membrane-Inserted Toxins in Lipid Bilayer Nanodiscs
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Akkaladevi, Narahari, Mukherjee, Srayanta, Katayama, Hiroo, Janowiak, Blythe, Patel, Deepa, Gogol, Edward P., Pentelute, Bradley L., John Collier, R., and Fisher, Mark T.
- Published
- 2015
- Full Text
- View/download PDF
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