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Your search keyword '"Jang, Hyun Gyung"' showing total 26 results

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1. Preclinical evaluation of stereopure antisense oligonucleotides for allele-selective lowering of mutant HTT

2. OSWG Recommended Approaches to the Nonclinical Pharmacokinetic (ADME) Characterization of Therapeutic Oligonucleotides

3. Supplementary Methods, Supplementary Results, Supplementary Table 1, Supplementary Figures 1-8 from The Potent ALK Inhibitor Brigatinib (AP26113) Overcomes Mechanisms of Resistance to First- and Second-Generation ALK Inhibitors in Preclinical Models

4. Data from The Potent ALK Inhibitor Brigatinib (AP26113) Overcomes Mechanisms of Resistance to First- and Second-Generation ALK Inhibitors in Preclinical Models

6. Cancer-associated IDH1 mutations produce 2-hydroxyglutarate

7. Variant-selective stereopure oligonucleotides protect against pathologies associated with C9orf72-repeat expansion in preclinical models

10. RELATIONSHIP BETWEEN SERIAL MEASUREMENTS OF LV EJECTION FRACTION AND CARDIOVASCULAR EVENTS IN PATIENTS WITH ACUTE CORONARY SYNDROME

11. 2018 White Paper on Recent Issues in Bioanalysis: ‘A global bioanalytical community perspective on last decade of incurred samples reanalysis (ISR)’ (Part 1 – small molecule regulated bioanalysis, small molecule biomarkers, peptides & oligonucleotide bioanalysis)

12. TCT-652 Coronary Artery Calcium Score in Predicting Periprocedural Myocardial Infarction in Patients Undergoing Elective Percutaneous Coronary Intervention

13. Stereopure Antisense Oligonucleotides Preferentially Knockdown G4C2 Repeat-Containing C9ORF72 Transcripts: A Potential Therapeutic Approach for the Treatment of Amyotrophic Lateral Sclerosis (ALS) and Frontotemporal Dementia (FTD) (N2.002)

14. The Potent ALK Inhibitor Brigatinib (AP26113) Overcomes Mechanisms of Resistance to First- and Second-Generation ALK Inhibitors in Preclinical Models

15. Discovery of Brigatinib (AP26113), a Phosphine Oxide-Containing, Potent, Orally Active Inhibitor of Anaplastic Lymphoma Kinase

16. THE INVESTIGATIONAL STEREOPURE ANTISENSE OLIGONUCLEOTIDE WVE-3972-01 PREFERENTIALLY REDUCES G4C2 REPEAT-CONTAINING C9ORF72 TRANSCRIPTS: A POTENTIAL THERAPEUTIC APPROACH FOR THE TREATMENT OF FRONTOTEMPORAL DEMENTIA

17. Coronary artery calcium score in predicting periprocedural myocardial infarction in patients undergoing an elective percutaneous coronary intervention.

18. Abstract 2993: Patterns of recurrent mutations in SETBP1 mutated and wild-type atypical Chronic Myeloid Leukemia patients.

19. Abstract 3176: Recurrent SETBP1 mutations in atypical chronic myeloid leukemia abrogate an ubiquitination site and dysregulate SETBP1 protein levels.

20. Recurrent SETBP1 mutations in atypical chronic myeloid leukemia

21. Cancer-associated IDH1 mutations produce 2-hydroxyglutarate

22. Abstract 5452: Cancer-associated metabolite 2-hydroxyglutarate accumulates in AML with IDH1/2 mutations

23. Abstract 33: Cancer-associated IDH1 mutations produce 2-hydroxyglutarate

24. Cancer-associated metabolite 2-hydroxyglutarate accumulates in acute myelogenous leukemia with isocitrate dehydrogenase 1 and 2 mutations

25. Recurrent SETBP1 mutations in atypical chronic myeloid leukemia.

26. O4‐05‐02: THE INVESTIGATIONAL STEREOPURE ANTISENSE OLIGONUCLEOTIDE WVE‐3972‐01 PREFERENTIALLY REDUCES G4C2 REPEAT‐CONTAINING C9ORF72 TRANSCRIPTS: A POTENTIAL THERAPEUTIC APPROACH FOR THE TREATMENT...

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