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3. Essays on household debt, macroprudential policy and monetary policy in South Korea

Author

Jang, Hee Chang

Subjects
332.7
Abstract

Household debt in South Korea is high and still rising. Household debt to GDP ratio had risen at the similar pace with that in the US until 2007 but it has still been rising whereas it has been falling since 2017 in the US. As a result, it is now higher in South Korea than in the US. There was a dramatic growth in household debt in the US preceding the recent Great Recession and high level of household debt was viewed to amplify the severity of economic recession in the US constraining consumer spending. In this context, high and continuously rising household debt could be a potential risk factor for the South Korean economy. Macroprudential policy, which indicates policy aims to reduce financial systemic risk pre-emptively, is a crucial measure to slow down the pace of household debt growth in South Korea. However, there is no established tool to analyse or evaluate its effects and relationship to monetary policy. The second chapter presents the trend and distribution of household debt in South Korea, and brief history of policy responses to continuously increasing household debt. The third chapter shows how macroprudential policy works by using a simple heterogeneous DSGE model with collateral constraint. The model is based on so-called borrower-saver model. Despite of its simplicity, the model can clearly explain how macroprudential policy affects household debt and related variables in South Korea. In addition, dynamics of this model imply increasing amortisation rate is superior measure to decreasing LTV ratio because it induces less volatility in economy. The collateral constraint in this thesis is designed to distinguish household debt (stock) and borrowing (flow). As a result, it is more realistic than the one mostly used in literature. This collateral constraint setting contributes to the better results especially when we analyse the phase of tightening household credit conditions. Furthermore, it enables us to see how amortization rate affects the South Korean economy. The fourth chapter extends the model mainly to see how credit tightening and monetary policy work differently and how they interact. Habit formation in non-durable good consumption, price rigidity in non-durable good producers, fixed cost in intermediate good production and monetary policy are added in the model. Not only the newly added elements themselves but also inflation make model's responses different from those in the previous chapter. Nominal and real rigidities make dynamics last longer and more realistic. Due to the structure of collateral constraint, a rise in inflation can reduce the level of real household debt whereas there is no inflation effect on real household debt with the common type of collateral constraint. This also influences responses to monetary policy shock. The results demonstrate credit tightening is better than monetary policy in slowing down the growth rate of household debt. Among all policy measures considered, decreasing amortization rate is the most effective and increasing LTV ratio is the second. These implies that ongoing policy efforts to slow down the growth rate of household debt in South Korea is on the right track. The fifth chapter shows welfare effects of macroprudential policy. The results illustrate it is impossible to get social welfare gains in a situation given in South Korea when discretionary macroprudential policy comes into effect. If government adopts countercyclical macroprudential rule, it is possible to improve social welfare but it requires welfare loss either of borrower or saver.

Published
2017

5. The Association Between Antibody Responses and Prolonged Viable Severe Acute Respiratory Syndrome Coronavirus 2 Shedding in Immunocompromised Patients: A Prospective Cohort Study.

Author

Lim, So Yun, Kim, Jun-Won, Kim, Ji Yeun, Kang, Sung-Woon, Jang, Choi-Young, Chang, Euijin, Yang, Jeong-Sun, Kim, Kyung-Chang, Jang, Hee-Chang, Kim, Da Sol, Shin, Younmin, Lee, Joo-Yeon, and Kim, Sung-Han

Subjects
SARS-CoV-2, ANTIBODY formation, IMMUNOCOMPROMISED patients, COVID-19, IMMUNOGLOBULIN G
Abstract

Immunocompromised patients with coronavirus disease 2019 were prospectively enrolled from March to November 2022 to understand the association between antibody responses and severe acute respiratory syndrome coronavirus 2 shedding. A total of 62 patients were analyzed, and the results indicated a faster decline in genomic and subgenomic viral RNA in patients with higher neutralizing and S1-specific immunoglobulin G (IgG) antibodies (both P <.001). Notably, high neutralizing antibody levels were associated with a significantly faster decrease in viable virus cultures (P =.04). Our observations suggest the role of neutralizing antibodies in prolonged virus shedding in immunocompromised patients, highlighting the potential benefits of enhancing their humoral immune response through vaccination or monoclonal antibody treatments. [ABSTRACT FROM AUTHOR]

Published
2024
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7. 1361. The association between antibody responses and prolonged viable SARS-CoV-2 shedding in immunocompromised patients: a prospective cohort study

Author

Lim, So Yun, primary, Kim, Jun-Won, additional, Kim, Ji Yeun, additional, Kang, Sung-Woon, additional, Jang, Choi-Young, additional, Chang, Eui Jin, additional, Yun, Sung-Cheol, additional, Yang, Jeong-Sun, additional, Kim, Kyung-Chang, additional, Jang, Hee-Chang, additional, Kim, Dasol, additional, Shin, Younmin, additional, Lee, Joo-Yeon, additional, and Kim, Sung-Han, additional

Published
2023
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8. 86. Effect of Oral Fosfomycin Compared to the Intravenous Beta Lactam/Beta-Lactamase Inhibitor or Carbapenem in Step-down Treatment of Patients with Complicated Urinary Tract Infection due to Extended-Spectrum Beta-Lactamase (ESBL) Producing Enterobacteriaceae: A Multicenter, Open-label, Randomized Controlled, Non-inferiority Trial

Author

Seo, Jun-won, primary, Young Kim, Da, additional, Yoon, Youngmin, additional, Sang Lyu, Young, additional, Sub Na, Yong, additional, Sik Moon, Do, additional, Ra Yun, Na, additional, Seok Kim, Min, additional, Kim, Jeong-Han, additional, Woon Bae, Sang, additional, Hur, Jian, additional, Hyung Kim, Min, additional, Soo Park, Yoon, additional, Kim, Heejung, additional, Lee, Hyungdon, additional, Jang, Hee-Chang, additional, and Kim, Dong-Min, additional

Published
2023
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9. Virological characteristics and the rapid antigen test as deisolation criteria in immunocompromised patients with COVID‐19: A prospective cohort study

Author

Kang, Sung‐Woon, primary, Kim, Jun‐Won, additional, Kim, Ji Yeun, additional, Lim, So Yun, additional, Jang, Choi‐Young, additional, Chang, Euijin, additional, Yang, Jeong‐Sun, additional, Kim, Kyung‐Chang, additional, Jang, Hee‐Chang, additional, Kim, Dasol, additional, Shin, Younmin, additional, Lee, Joo‐Yeon, additional, and Kim, Sung‐Han, additional

Published
2023
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12. Propensity Score Matched Analysis for the Safety and Effectiveness of Remdesivir in COVID-19 Patients with Renal Impairment

Author

Yang, Eunmi, primary, Choi, Han Zo, additional, Kim, Subin, additional, Oh, Dong Hyun, additional, Ahn, Mi Young, additional, Ham, Sinyoung, additional, Lee, Eunyoung, additional, Jeon, Jaehyun, additional, Kim, Min-Kyung, additional, Jang, Hee-Chang, additional, Park, Sang-Won, additional, and Choi, Jae-Phil, additional

Published
2023
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13. Heterologous ChAdOx1 and Bnt162b2 vaccination induces strong neutralizing antibody responses against SARS-CoV-2 including delta variant with tolerable reactogenicity

Author

Bae, Seongman, Ko, Jae-Hoon, Choi, Ju-Yeon, Park, Woo-Jung, Lim, So Yun, Ahn, Jin Young, Song, Kyoung-Ho, Lee, Kyoung Hwa, Song, Young Goo, Chan Kim, Yong, Park, Yoon Soo, Choi, Won Suk, Jeong, Hye Won, Kim, Shin-Woo, Kwon, Ki Tae, Kang, Eun-Suk, Kim, Ah-Ra, Jang, Sundong, Kim, Byoungguk, Kim, Sung Soon, Jang, Hee-Chang, Choi, Jun Yong, Kim, Sung-Han, and Peck, Kyong Ran

Published
2022
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18. Gender affects prognosis of methicillin-resistant Staphylococcus aureus bacteremia differently depending on the severity of underlying disease

Author

Kang, Chang Kyung, Kwak, Yee Gyung, Park, Youngmi, Song, Kyoung-Ho, Kim, Eu Suk, Jung, Sook-In, Park, Kyung-Hwa, Park, Wan Beom, Kim, Nam Joong, Kim, Young Keun, Jang, Hee-Chang, Lee, Shinwon, Jeon, Jae Hyun, Kwon, Ki Tae, Kim, Chung-Jong, Kim, Yeon-Sook, Kim, Hong Bin, and the Korea INfectious Diseases (KIND) study group

Published
2018
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19. Severe fever with thrombocytopenia syndrome: comparison with scrub typhus and clinical diagnostic prediction

Author

Park, Sang-Won, Lee, Chang-Seop, Kim, Jeong-Han, Bae, In-Gyu, Moon, Chisook, Kwak, Yee Gyung, Kim, Baek-Nam, Lee, Jae Hoon, Ryu, Seong Yeol, Jang, Hee-Chang, Hur, Jian, Jun, Jae-Bum, Jung, Younghee, Chang, Hyun-Ha, Kim, Young Keun, Hwang, Jeong-Hwan, Kim, Yeon-Sook, Jeong, Hye Won, Song, Kyoung-Ho, Park, Wan Beom, Kim, Eu Suk, and Oh, Myoung-don

Published
2019
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20. Short-Term Effectiveness of Oral Nirmatrelvir/Ritonavir Against the SARS-CoV-2 Omicron Variant and Culture-Positive Viral Shedding

Author

Lee, Eunyoung, primary, Park, Sehee, additional, Choi, Jae-Phil, additional, Kim, Min-Kyung, additional, Yang, Eunmi, additional, Ham, Sin Young, additional, Lee, Seungjae, additional, Lee, Bora, additional, Yang, Jeong-Sun, additional, Park, Byoung Kwon, additional, Kim, Da Sol, additional, Lee, So-Young, additional, Lee, Joo-Yeon, additional, Jang, Hee-Chang, additional, Jeon, Jaehyun, additional, and Park, Sang-Won, additional

Published
2023
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21. Magnitude and Duration of Serum Neutralizing Antibody Titers Induced by a Third mRNA COVID-19 Vaccination against Omicron BA.1 in Older Individuals

Author

Park, Jun-Sun, primary, Jeon, Jaehyun, additional, Um, Jihye, additional, Choi, Youn Young, additional, Kim, Min-Kyung, additional, Lee, Kyung-Shin, additional, Sung, Ho Kyung, additional, Jang, Hee-Chang, additional, Chin, BumSik, additional, Kim, Choon Kwan, additional, Oh, Myung-don, additional, and Lee, Chang-Seop, additional

Published
2023
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22. Real-World Effectiveness of Nirmatrelvir-Ritonavir and Its Acceptability in High-Risk COVID-19 Patients

Author

Kim, Min-Kyung, primary, Lee, Kyung-Shin, additional, Ham, Sin Young, additional, Choi, Youn Young, additional, Lee, Eunyoung, additional, Lee, Seungjae, additional, Lee, Bora, additional, Jeon, Jaehyun, additional, Chin, BumSik, additional, Kim, Yeonjae, additional, Kim, Gayeon, additional, Jang, Hee-Chang, additional, Choi, Jae-Phil, additional, and Park, Sang-Won, additional

Published
2023
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23. Characteristics and risk factors of prolonged viable virus shedding in immunocompromised patients with COVID-19: a prospective cohort study

Author

Kang, Sung-Woon, primary, Kim, Jun-Won, additional, Kim, Ji Yeun, additional, Lim, So Yun, additional, Jang, Choi-Young, additional, Chang, Euijin, additional, Yang, Jeong-Sun, additional, Kim, Kyung-Chang, additional, Jang, Hee-Chang, additional, Kim, Dasol, additional, Shin, Younmin, additional, Lee, Joo-Yeon, additional, and Kim, Sung-Han, additional

Published
2023
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25. Kinetics of vaccine-induced neutralizing antibody titers and estimated protective immunity against wild-type SARS-CoV-2 and the Delta variant: A prospective nationwide cohort study comparing three COVID-19 vaccination protocols in South Korea

Author

Nham, Eliel, primary, Ko, Jae-Hoon, additional, Song, Kyoung-Ho, additional, Choi, Ju-Yeon, additional, Kim, Eu Suk, additional, Kim, Hye-Jin, additional, Kim, Byoungguk, additional, Lim, Hee-Young, additional, Kim, Kyung-Chang, additional, Jang, Hee-Chang, additional, Lee, Kyoung Hwa, additional, Song, Young Goo, additional, Baek, Yae Jee, additional, Ahn, Jin Young, additional, Choi, Jun Yong, additional, Kim, Yong Chan, additional, Park, Yoon Soo, additional, Choi, Won Suk, additional, Bae, Seongman, additional, Kim, Sung-Han, additional, Kang, Eun-Suk, additional, Jeong, Hye Won, additional, Kim, Shin-Woo, additional, Kwon, Ki Tae, additional, Kim, Sung Soon, additional, and Peck, Kyong Ran, additional

Published
2022
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32. Booster BNT162b2 COVID-19 Vaccination Increases Neutralizing Antibody Titers Against the SARS-CoV-2 Omicron Variant in Both Young and Elderly Adults

Author

Um, Jihye, primary, Choi, Youn Young, additional, Kim, Gayeon, additional, Kim, Min-Kyung, additional, Lee, Kyung-Shin, additional, Sung, Ho Kyung, additional, Kim, Byung Chul, additional, Lee, Yoo-kyoung, additional, Jang, Hee-Chang, additional, Bang, Ji Hwan, additional, Chung, Ki-hyun, additional, Oh, Myoung-don, additional, Park, Jun-Sun, additional, and Jeon, Jaehyun, additional

Published
2022
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33. Clinical Characteristics of 40 Patients Infected With the SARS-CoV-2 Omicron Variant in Korea

Author

Kim, Min-Kyung, primary, Lee, Bora, additional, Choi, Youn Young, additional, Um, Jihye, additional, Lee, Kyung-Shin, additional, Sung, Ho Kyung, additional, Kim, Yeonjae, additional, Park, Jun-Sun, additional, Lee, Myungsun, additional, Jang, Hee-Chang, additional, Bang, Ji Hwan, additional, Chung, Ki-hyun, additional, and Jeon, Jaehyun, additional

Published
2022
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35. Additional file 1 of Genomic characterization of nine Clostridioides difficile strains isolated from Korean patients with Clostridioides difficile infection

Author

Ahn, Seung Woo, Lee, Se Hee, Kim, Uh Jin, Jang, Hee-Chang, Choi, Hak-Jong, Choy, Hyon E., Kang, Seung Ji, and Roh, Seong Woon

Abstract

Additional file 1: Fig. S1. Pan- and core-genome box plot of 60 C. difficile strains with standard deviations. The pan-genome represents the total set of genes of the 60 C. difficile strains, while the core-genome represents the common genes across all genomes. Fig. S2. In silico DNA-DNA hybridization (DDH) analyses showing the pair-wise relatedness of 60 C. difficile strains and two reference strains (C. mangenotii DSM 1289T and Clostridium hiranonis TO-931). Strains CBA7201–CBA7209 isolated from Korean patients with CDI are highlighted in bold. The hierarchical clusters represented by dendrograms were constructed by simple linkage of the in silico DDH values. The vertical bar on the right side of the figure indicates the MLST clade to which each C. difficile strain belongs. Fig. S3. Diagram of the structural components involved in C. difficile flagella assembly defined by the number of KEGG orthology genes identified from the genomes of 60 C. difficile strains. Flagella assembly genes belonging to the core genome of the 60 C. difficile strains are indicated in red; flagella assembly genes belonging to the accessory genome identified from 2–56 genomes are indicated in blue.

Published
2021
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37. Risk Factors and a Scoring System to Predict ARDS in Patients with COVID-19 Pneumonia in Korea: A Multicenter Cohort Study

Author

Seo, Jun-Won, primary, Kim, Seong Eun, additional, Choi, Eun Young, additional, Hong, Kyung Soo, additional, Oh, Tae Hoon, additional, Kim, Uh. Jin, additional, Kang, Seung-Ji, additional, Park, Kyung-Hwa, additional, Jung, Sook-In, additional, Kim, Da Young, additional, Yun, Na Ra, additional, Kim, Dong-Min, additional, Kim, Hwa Pyung, additional, Hur, Jian, additional, and Jang, Hee-Chang, additional

Published
2021
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38. Dysfunctional accessory gene regulator (agr) as a prognostic factor in invasive Staphylococcus aureus infection: a systematic review and meta-analysis

Author

National Research Foundation of Korea, Ministry of Education, Science and Technology (South Korea), Lee, Soon Ok, Lee, Shinwon, Lee, Jeong-Eun, Song, Kyoung-Ho, Kang, Chang Kyung, Wi, Yu Mi, San Juan, Rafael, López-Cortés, Luis Eduardo, Lacoma, Alicia, Prat, Cristina, Jang, Hee-Chang, Kim, Eu Suk, Kim, Hong Bin, Lee, Sun Hee, National Research Foundation of Korea, Ministry of Education, Science and Technology (South Korea), Lee, Soon Ok, Lee, Shinwon, Lee, Jeong-Eun, Song, Kyoung-Ho, Kang, Chang Kyung, Wi, Yu Mi, San Juan, Rafael, López-Cortés, Luis Eduardo, Lacoma, Alicia, Prat, Cristina, Jang, Hee-Chang, Kim, Eu Suk, Kim, Hong Bin, and Lee, Sun Hee

Abstract

The accessory gene regulator (agr) locus of Staphylococcus aureus is a quorum-sensing virulence regulator. Although there are many studies concerning the effect of dysfunctional agr on the outcomes of S. aureus infection, there is no systematic review to date. We systematically searched for clinical studies reporting outcomes of invasive S. aureus infections and the proportion of dysfunctional agr among their causative strains, and we performed a meta-analysis to obtain estimates of the odds of outcomes of invasive S. aureus infection with dysfunctional versus functional agr. Of 289 articles identified by our research strategy, 20 studies were meta-analysed for crude analysis of the impact of dysfunctional agr on outcomes of invasive S. aureus infection. Dysfunctional agr was generally associated with unfavourable outcomes (OR 1.32, 95% CI 1.05–1.66), and the impact of dysfunctional agr on outcome was more prominent in invasive methicillin-resistant S. aureus (MRSA) infections (OR 1.54, CI 1.20–1.97). Nine studies were meta-analysed for the impact of dysfunctional agr on the 30-day mortality of invasive S. aureus infection. Invasive MRSA infection with dysfunctional agr exhibited higher 30-day mortality (OR 1.40, CI 1.03–1.90) than that with functional agr. On the other hand, invasive MSSA infection with dysfunctional agr exhibited lower 30-day mortality (OR 0.51, CI 0.27–0.95). In the post hoc subgroup analysis by the site of MRSA infection, dysfunctional agr was associated with higher 30-day mortality in MRSA pneumonia (OR 2.48, CI 1.17–5.25). The effect of dysfunctional agr on the outcome of invasive S. aureus infection may vary depending on various conditions, such as oxacillin susceptibility and the site of infection. Dysfunctional agr was generally associated with unfavourable clinical outcomes and its effect was prominent in MRSA and pneumonia. Dysfunctional agr may be applicable for outcome prediction in cases of invasive MRSA infection with hardly eradicabl

Published
2020

39. Correction: Risk factors for critical COVID-19 illness during Delta- and Omicron-predominant period in Korea; using K-COV-N cohort in the National health insurance service.

Author

Lee, Kyung-Shin, Go, Min Jin, Choi, Youn Young, Kim, Min-Kyung, Seong, Jaehyun, Sung, Ho Kyung, Jeon, Jaehyun, Jang, Hee-Chang, and Kim, Myoung-Hee

Subjects
NATIONAL health insurance, COVID-19 pandemic, CRITICALLY ill
Abstract

This document is a correction notice for a study titled "Risk factors for critical COVID-19 illness during Delta- and Omicron-predominant period in Korea; using K-COV-N cohort in the National health insurance service." The correction pertains to the funding statement, which was published incorrectly. The correct funding statement acknowledges that the study was conducted as part of a public-private joint research effort on COVID-19, co-hosted by the KDCA (Korea Disease Control and Prevention Agency) and the NHIS (National Health Insurance Service) in South Korea. The study also received support from the Korea National Institute of Health. The funders did not have any involvement in the study design, data collection and analysis, decision to publish, or manuscript preparation. [Extracted from the article]

Published
2024
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40. Microbial Etiology of Pyogenic Vertebral Osteomyelitis According to Patient Characteristics

Author

Kim, Dong Youn, primary, Kim, Uh Jin, primary, Yu, Yohan, primary, Kim, Seong-Eun, primary, Kang, Seung-Ji, primary, Jun, Kang-Il, primary, Kang, Chang Kyung, primary, Song, Kyoung-Ho, primary, Choe, Pyoeng Gyun, primary, Kim, Eu Suk, primary, Kim, Hong Bin, primary, Jang, Hee-Chang, primary, Jung, Sook In, primary, Oh, Myoung-don, primary, Park, Kyung-Hwa, primary, and Kim, Nam Joong, primary

Published
2020
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41. Lipocalin2 Induced by Bacterial Flagellin Protects Mice against Cyclophosphamide Mediated Neutropenic Sepsis

Author

Lim, Daejin, primary, Kim, Hee Kyung, additional, Jeong, Jae-Ho, additional, Jung, Yoon Seok, additional, Lee, Shee Eun, additional, Jang, Hee-Chang, additional, Jung, Sook-In, additional, Choi, Hueng-Sik, additional, Rhee, Joon Haeng, additional, Lee, Sung-Gwon, additional, Park, Chungoo, additional, Song, Miryoung, additional, and Choy, Hyon E., additional

Published
2020
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42. Viral Load Kinetics of SARS-CoV-2 Infection in Saliva in Korean Patients: a Prospective Multi-center Comparative Study

Author

Kim, Seong Eun, primary, Lee, Ji Yeon, additional, Lee, Ahrang, additional, Kim, Soosung, additional, Park, Kyung-Hwa, additional, Jung, Sook-In, additional, Kang, Seung-Ji, additional, Oh, Tae Hoon, additional, Kim, Uh Jin, additional, Lee, Seung Yeob, additional, Kee, Seung-Jung, additional, and Jang, Hee-Chang, additional

Published
2020
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47. 260. Detection of Aspergillus fumigatus Infection in Mice with 2-Deoxy-2-[18F]fluorosorbitol

Author

Yu, Yohan, primary, ji Kang, Seung, additional, Kim, Dong-Yeon, additional, Pyo, Ayoung, additional, Ji, Sehyeon, additional, Chuluunkhuu, Baigali, additional, Kim, Soosung, additional, un Shin, Sung, additional, Hoon Oh, Tae, additional, Jin Kim, Uh, additional, Eun Kim, Seong, additional, Jang, Hee-Chang, additional, Park, Kyung-Hwa, additional, In Jung, Sook, additional, and Min, Jung-Joon, additional

Published
2019
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48. In VitroSynergy andIn VivoActivity of Tigecycline-Ciprofloxacin Combination Therapy against Vibrio vulnificus Sepsis

Author

Kim, Seong Eun, primary, Kim, Hee Kyung, additional, Choi, Su-Mi, additional, Yu, Yohan, additional, Kim, Uh Jin, additional, Darboe, Kalifa Sanneh, additional, Kang, Seung-Ji, additional, Park, Kyung-Hwa, additional, Kang, Gaeun, additional, Kim, Young Ran, additional, Rhee, Joon Haeng, additional, Jung, Sook-In, additional, and Jang, Hee-Chang, additional

Published
2019
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50. Outcomes of Third-Generation Cephalosporin Plus Ciprofloxacin or Doxycycline Therapy in Patients with Vibrio vulnificus Septicemia: A Propensity Score-Matched Analysis

Author

Kim, Seong Eun, primary, Shin, Sung Un, additional, Oh, Tae Hoon, additional, Kim, Uh Jin, additional, Darboe, Kalifa Sanneh, additional, Kang, Seung-Ji, additional, Jang, Hee-Chang, additional, Jung, Sook-In, additional, Shin, Hee-Young, additional, and Park, Kyung-Hwa, additional

Published
2019
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