340 results on '"Janel, Nathalie"'
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2. Exploring the link between hedonic overeating and prefrontal cortex dysfunction in the Ts65Dn trisomic mouse model
3. EGCG-like non-competitive inhibitor of DYRK1A rescues cognitive defect in a down syndrome model
4. Representations of protein structure for exploring the conformational space: A speed–accuracy trade-off
5. An information gain-based approach for evaluating protein structure models
6. Spermatogonial depletion and a spermatogenesis defect in the Dp(16)1Yey mouse model of Down syndrome.
7. Ethanol-Induced Changes in Brain of Transgenic Mice Overexpressing DYRK1A
8. Down syndrome and infertility: what support should we provide?
9. LPS-Induced Inflammation Abolishes the Effect of DYRK1A on IkB Stability in the Brain of Mice
10. Exploring the Link between Hedonic Overeating and Prefrontal Cortex Dysfunction in the Ts65Dn Trisomic Mouse Model
11. Over‐expression of Dyrk1A affects bleeding by modulating plasma fibronectin and fibrinogen level in mice
12. Traitement prénatal des troubles du neurodéveloppement : étude de l’effet d’un peptide neuroprotecteur chez un modèle murin de trisomie 21
13. Overexpression of the DYRK1A Gene (Dual-Specificity Tyrosine Phosphorylation-Regulated Kinase 1A) Induces Alterations of the Serotoninergic and Dopaminergic Processing in Murine Brain Tissues
14. COVID-19 and Down’s syndrome: are we heading for a disaster?
15. Inhibition of DYRK1A proteolysis modifies its kinase specificity and rescues Alzheimer phenotype in APP/PS1 mice
16. Overeating in the Ts65Dn trisomic mouse model is associated with dopaminergic neurotransmission deficit in the prefrontal cortex
17. Type 2 Diabetes Mellitus and Alzheimer’s Disease: Shared Molecular Mechanisms and Potential Common Therapeutic Targets
18. DYRK1A and Activity-Dependent Neuroprotective Protein Comparative Diagnosis Interest in Cerebrospinal Fluid and Plasma in the Context of Alzheimer-Related Cognitive Impairment in Down Syndrome Patients
19. Molecular Rescue of DYRK1A Overexpression in Cystathionine Beta Synthase-Deficient Mouse Brain by Enriched Environment Combined with Voluntary Exercise
20. Homocysteine Metabolism Pathway Is Involved in the Control of Glucose Homeostasis: A Cystathionine Beta Synthase Deficiency Study in Mouse
21. Catechins as a Potential Dietary Supplementation in Prevention of Comorbidities Linked with Down Syndrome
22. Cadmium Alters the Biotransformation of Carcinogenic Aromatic Amines by Arylamine N-Acetyltransferase Xenobiotic-Metabolizing Enzymes: Molecular, Cellular, and in Vivo Studies
23. Connexin30 Deficiency Causes Instrastrial Fluid-Blood Barrier Disruption within the Cochlear Stria Vascularis
24. Exploring the Structural Rearrangements of the Human Insulin-Degrading Enzyme through Molecular Dynamics Simulations
25. Dyrk1a haploinsufficiency induces diabetes in mice through decreased pancreatic beta cell mass
26. DYRK1A Overexpression in Mice Downregulates the Gonadotropic Axis and Disturbs Early Stages of Spermatogenesis
27. Effects of red wine polyphenolic compounds on paraoxonase-1 and lectin-like oxidized low-density lipoprotein receptor-1 in hyperhomocysteinemic mice
28. DYRK1A BAC Transgenic Mouse: A New Model of Thyroid Dysgenesis in Down Syndrome
29. Mice Deficient in Cystathionine Beta Synthase Display Increased Dyrk1A and SAHH Activities in Brain
30. Effect of catechin/epicatechin dietary intake on endothelial dysfunction biomarkers and proinflammatory cytokines in aorta of hyperhomocysteinemic mice
31. Dyrk1A, a Serine/Threonine Kinase, is Involved in ERK and Akt Activation in the Brain of Hyperhomocysteinemic Mice
32. List of Contributors
33. Protection and Reversal of Hepatic Fibrosis by Polyphenols
34. Metabolic Diseases and Down Syndrome: How Are They Linked Together?
35. BDNF and DYRK1A Are Variable and Inversely Correlated in Lymphoblastoid Cell Lines from Down Syndrome Patients
36. Myocardial fibrosis and TGFB expression in hyperhomocysteinemic rats
37. Optimisation of microwave-assisted extraction of prune (Prunus domestica) antioxidants by response surface methodology
38. Epigallocatechin-3-gallate, a DYRK1A inhibitor, rescues cognitive deficits in Down syndrome mouse models and in humans
39. Molecular Rescue of Dyrk1A Overexpression Alterations in Mice with Fontup® Dietary Supplement: Role of Green Tea Catechins
40. Hyperhomocysteinemia due to cystathionine beta synthase deficiency induces dysregulation of genes involved in hepatic lipid homeostasis in mice
41. Mice lacking cystathionine beta synthase have lung fibrosis and air space enlargement
42. Safety and preliminary efficacy on cognitive performance and adaptive functionality of epigallocatechin gallate (EGCG) in children with Down syndrome. A randomized phase Ib clinical trial (PERSEUS study)
43. Thiol compounds metabolism in mice, rats and humans: Comparative study and potential explanation of rodents protection against vascular diseases
44. Ets transcription factors bind and transactivate the core promoter of the von Willebrand factor gene
45. Additional file 6: of Inhibition of DYRK1A proteolysis modifies its kinase specificity and rescues Alzheimer phenotype in APP/PS1 mice
46. LPS-Induced Inflammation Abolishes the Effect of DYRK1A on IkB Stability in the Brain of Mice
47. The neuronal SAPK/JNK pathway is altered in a murine model of hyperhomocysteinemia
48. Deciphering the Link Between Hyperhomocysteinemia and Ceramide Metabolism in Alzheimer-Type Neurodegeneration
49. Hypothesis and Theory: Circulating Alzheimer's-Related Biomarkers in Type 2 Diabetes. Insight From the Goto-Kakizaki Rat
50. Prenatal treatment with EGCG enriched green tea extract rescues GAD67 related developmental and cognitive defects in Down syndrome mouse models
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