132 results on '"Jané Salas E"'
Search Results
2. Antimicrobial prophylaxis in dentistry
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Merlos, A., Vinuesa, T., Jané-Salas, E., López-López, J., and Viñas, M.
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- 2014
- Full Text
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3. Implantes dentales en pacientes con liquen plano oral. Revisión sistemática
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Frexes Argemí,R, Céspedes,JM, Saka Herran,C, Marí Roig,A, Jané Salas,E, Estrugo Devesa,A, and López López,J
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Otorhinolaryngology ,liquen plano oral ,implantes dentales ,General Dentistry - Abstract
RESUMEN Introducción: El liquen plano se considera una enfermedad muco-cutánea crónica, en la que la etiopatogenia se considera una alteración autoinmune mediada por células, con una prevalencia entre 0.5 y 2%. La colocación de implantes dentales en pacientes con dicha enfermedad puede hacer cambiar el éxito del tratamiento. Material y Método: se realizó una búsqueda en la base de datos Pub Med y Med line, utilizándose como palabras clave: “lichen planus” y "dental implant". El criterio de inclusión fue de estudios en humanos con liquen plano oral a los que se les había tratado con implantes dentales osteointegrados publicados en lengua inglesa que sean observacionales, experimentales y series de casos publicados entre 1990 y 2020. Resultados: Se selecciona un total de 13 artículos, la N total de implantes fue de 362 implantes colocados en 148 pacientes. El seguimiento de los implantes es de 2 a 10 años. Hay un fracaso de 45 (12,43%) implantes, de los cuales 42 sucede en pacientes con liquen plano activo y 3 en cuadros de liquen erosivo sin especificar si está en fase activa o no. La tasa de fracaso fue mayor en las mujeres (61%) en comparación con los hombres (44%). En uno de los casos, se diagnostica carcinoma oral de células escamosas [COCE] 3 años después de la colocación del implante, lo que corresponde al 0,2% de los casos. Conclusión: el liquen plano oral es una enfermedad autoinmune que debemos tener en cuenta cuando colocamos implantes y controlar periódicamente.
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- 2021
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4. Papel de la histamina en el Liquen Plano Oral, Leucoplasia y en el Carcinoma Oral de Células Escamosas. Revisión sistemática
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Bertran-Faus, A, primary, Polis-Yanes, C, additional, González-Navarro, B, additional, Jané-Salas, E, additional, Estrugo Devesa, A, additional, Marí-Roig, A, additional, and López-López, J, additional
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- 2021
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5. Modificaciones en la microbiota y los factores inflamatorios después de la utilización de un dentífrico con aceite de oliva virgen, betaina y xilitol, desarrollado para el cuidado del microbioma oral: Estudio clínico piloto.
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López-López, J., Aumedes, T. Vinuesa, Egido Moreno, S., Carcamo España, V., Riveros, T. V. Pereira, and Jané Salas, E.
- Abstract
Copyright of Avances en Odontoestomatologia is the property of Ediciones Avances SL and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
- Published
- 2023
6. Postsurgical Prosthetic Rehabilitation after Mandibular Ameloblastoma Resection: A 7-Year Follow-Up Case Report
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Moreno-Soriano, C., Estrugo-Devesa, A., Castañeda-Vega, P., Jané-Salas, E., and López-López, J.
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Article Subject - Abstract
Ameloblastomas are benign but locally invasive odontogenic tumors most frequently located in the mandible. The gold standard of treatment is the surgical resection of the tumor with safety margins. Postsurgical defects generate a significant morbidity that needs reconstruction and oral rehabilitation to restore the oral functions. This case report describes the prosthetic rehabilitation of a 42-year-old male after resection of a mandibular ameloblastoma. Excision of the lesion by segmental mandibulectomy and mandibular reconstruction by microvascularized fibula flap was performed. After placement of 6 dental implants, the patient was rehabilitated with a lower hybrid prosthesis fabricated using computer-aided design-computer-aided manufacturing. During a 7-year and 5-month follow-up, some clinical complications were observed.
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- 2021
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7. Sífilis: manifestaciones orales, revisión sistemática
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Apoita Sanz, M., González Navarro, B., Jané-Salas, E., Marí Roig, A., Estrugo Devesa, A., and López-López, J.
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sexually transmitted diseases ,venereal diseases ,tertiary syphilis ,syphilis ,the great imitator ,enfermedades venéreas ,manifestaciones orales de la sífilis ,enfermedades de transmisión sexual ,sífilis primaria ,sífilis secundaria ,la gran imitadora ,secondary syphilis ,primary syphilis ,syphilis oral manifestations ,sífilis terciaria - Abstract
RESUMEN Introducción: la sífilis es una infección bacteriana, que se puede transmitir por contacto sexual o de forma congénita. Esta enfermedad consta de tres estadios, en los cuales se pueden dar diferentes manifestaciones orales. Material y método: se realizó una búsqueda en la base de datos PubMed, utilizándose como palabras clave: “sexually transmitted diseases”, “venereal diseases”, “syphilis”, “primary syphilis”, “secondary syphilis”, “tertiary syphilis”, “oral manifestations”, “oral lesions”. Como criterios de inclusión se emplearon: series de casos, estudios en los que el tema principal fueran las manifestaciones orales de la sífilis y trabajos en inglés y español. No hubo restricción por fecha. Resultados: se seleccionaron un total de 18 artículos, la N total de pacientes fue de 201. El 10,05% padecía sífilis primaria, el 52,76% sífilis secundaria y el 36, 68% sífilis terciaria. Las lesiones orales predominantes de la sífilis primaria fueron úlceras, inflamación, chancro sifilítico; en la sífilis secundaria se apreciaban placas mucosas, lesiones eritematosas, inflamación, lesiones papulares, lesiones maculares, lesiones erosivas; en la sífilis terciaria aparecen gomas sifilíticos, lesiones leucoplásicas y atrofia lingual. Discusión: la sífilis es una infección bacteriana que puede simular diversas enfermedades, es muy importante tenerla en cuenta a la hora de realizar el diagnóstico diferencial de diversas lesiones orales, sobre todo aquellas que se presentan de forma ulcerosa, indurada y asintomática. ABSTRACT Introduction: syphilis is a bacterial infection, which is transmitted by sexual contact or congenitally. This disease develops in three stages, in which different oral manifestations can occur. Material and method: a search was made in the PubMed database, using as keywords: “sexually transmitted diseases”, “venereal diseases”, “syphilis”, “primary syphilis”, “secondary syphilis”, “tertiary syphilis”, “Oral manifestations”, “oral lesions”. The inclusion criteria were: case series, studies in which the main theme was the oral manifestations of syphilis and works in English and Spanish. There was no restriction by date. Results: a total of 18 articles were selected, the total sample of patients was 201. 10.05% had primary syphilis, 52.76% secondary syphilis and 36, 68% tertiary syphilis. The predominant oral lesions of primary syphilis were ulcers, inflammation, syphilitic chancre; in secondary syphilis there were mucous patches, erythematous lesions, inflammation, papular lesions, macular lesions, erosive lesions; in tertiary syphilis, syphilitic gums, leukoplastic lesions and lingual atrophy. Discussion: Syphilis is a bacterial infection that can simulate various diseases, it is very important to take it into account when making the differential diagnosis of various oral lesions, especially those that occur in an ulcerative, indurated and asymptomatic form.
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- 2020
8. Factors associated with the malignization of oral lichen planus. Review of the literature
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Asensi Anta, E, Sardañés Martínez, S, Izquierdo Gómez, K, Jané Salas, E, Estrugo Debesa, A, and López López, J
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stomatognathic diseases ,Liquen plano oral ,Oral cancer ,Oral lichen planus ,Transformación maligna del liquen plano ,Carcinoma de células escamosas ,Cáncer oral ,Malignant transformation of oral lichen planus ,Squamous cell oral carcinoma - Abstract
RESUMEN Introcucción: El liquen plano (LP) es una enfermedad sistémica autoinmune de etiología desconocida y curso crónico que puede resultar en el desarrollo de carcinoma oral de células escamosas (COCE). Objetivo: Evaluar la evidencia relacionada con la malignización del LPO, así como las características clínicas y la incidencia de las lesiones que pueden desarrollan un COCE. Material y métodos: Se revisa la base de datos MEDLINE PubMed de los últimos 5 años (2013-2018) utilizando las siguientes palabras clave: “malignant transformation of oral lichen planus” and “squamous cell oral carcinoma”. Resultados: Se obtuvieron 48 artículos de los cuales tras la lectura resúmenes y la aplicación de nuestros criterios de inclusión y exclusión obtuvimos un total de 19 artículos, además de los 4 artículos añadidos mediante búsqueda manual. La revisión se basa en la comparación de 9 estudios de cohortes para analizar la incidencia de la progresión de LPO a COCE. Conclusiones: Debemos considerar el LPO como una enfermedad potencialmente maligna (0.5- 1%) siendo el sexo femenino, el tipo erosivo y la localización en la lengua factores de riesgo para la transformación a COCE. Teniendo en cuenta el riesgo de malignización es esencial el control de las lesiones para poder realizar un diagnóstico precoz. ABSTRACT Introduction: Lichen planus (LP) is a systemic autoimmune disease of unknown etiology and chronic course that can result in the development of oral squamous cell carcinoma (OECD). Objective: To evaluate the evidence related to the malignization of the LPO as well as the clinical characteristics and the incidence of the lesions that can develop a COCE. Material and methods: The MEDLINE PubMed database of the last 5 years (2013-2018) was reviewed using the following keywords: “malignant transformation of oral lichen planus” and “squamous cell oral carcinoma”. Results: 48 articles were obtained, after reading the summaries and applying our inclusion and exclusion criteria, we obtained a total of 19 articles, in addition to the 4 articles added by manual search. The review is based on the comparison of 9 cohort studies to analyze the incidence of progression from LPO to COCE. Conclusions: We should consider the LPO as a potentially malignant disease (0.5-1%), being the female sex, the erosive type and the localization in the tongue as a risk factors for the transformation to COCE. Taking into account the risk of malignancy, it is essential to control the lesions in order to make an early diagnosis.
- Published
- 2020
9. Late mandibular fracture after lower third molar extraction: a case report
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Olivera Oliva, A, Farnés Montpeyó, M, Estrugo Devesa, A, Jané Salas, E, Arranz Obispo, C, Marí Roig, A, and López-López, J
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stomatognathic diseases ,Complicación tardía ,stomatognathic system ,Fractura mandibular ,Complications after third molar removal ,Late complication ,Third molar ,Complicaciones después de la extracción del tercer molar ,Extraction ,Mandible fracture ,Extracción ,Tercer molar - Abstract
RESUMEN La extracción del tercer molar es un procedimiento común en cirugía oral. Una de las complicaciones es la fractura mandibular. Con una incidencia postoperatoria menor a un 0.005%. Los factores que contribuyen al riesgo de fractura del ángulo mandibular después de una extracción del tercer molar incluyen el nivel de impactación, la anatomía del diente, infecciones locales previas, edad, sexo, presencia de formaciones quísticas y bruxismo entre otras. Presentamos un caso clínico de fractura mandibular postoperatoria a las cinco semanas tras la exodoncia del 47 y 48 incluidos en posición horizontal. El objetivo final del tratamiento de una fractura mandibular es la consolidación ósea manteniendo la oclusión dental. En nuestro caso, al no tratarse de una fractura que sobrepasaba las corticales y sin desplazamiento mandibular, no fue subsidiaria de un tratamiento quirúrgico y se resolvió con reposo funcional. ABSTRACT The lower third molar extraction is a common procedure in oral surgery. One of its complications, although uncommon, is the mandibular fracture. Postoperatively, it has an incidence lower than 0.005%. The factors that may contribute to the risk of the mandibular angle fracture after an extraction of the third molar include the level of impaction are the anatomy of the tooth, previous local infections, age, sex, cysts and bruxism among others. We present a clinical case of postoperative mandibular fracture at five weeks after the extraction of 47 and 48 included in horizontal position. The ultimate treatment goal of a mandibular fracture is to reach a bone consolidation with the premorbid dental occlusion. In our case, as it was not a fracture that surpassed the cortical and there was not a mandibular displacement, it was not need a surgical treatment so it was resolved with functional rest.
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- 2020
10. Inferior alveolar nerve injury resulting from overextension of an endodontic sealer: non-surgical management using the GABA analogue pregabalin
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López-López, J., Estrugo-Devesa, A., Jané-Salas, E., and Segura-Egea, J. J.
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- 2012
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11. Incidence rate of metastases in the oral cavity: a review of all metastatic lesions in the oral cavity
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Oliver-Puigdomènech, C., primary, González-Navarro, B., additional, Polis-Yanes, C., additional, Estrugo-Devesa, A., additional, Jané-Salas, E., additional, and López-López, J., additional
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- 2021
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12. Update on the management of anticoagulated and antiaggregated patients in dental practice: Literature review
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Costa-Tort, J., primary, Schiavo-Di Flaviano, V., additional, González-Navarro, B., additional, Jané-Salas, E., additional, Estrugo-Devesa, A., additional, and López-López, J., additional
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- 2021
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13. COVID-19 and oral lesions, short communication and review
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Egido-Moreno, S., primary, Valls-Roca-Umbert, J., additional, Jané-Salas, E., additional, López-López, J., additional, and Estrugo-Devesa, A., additional
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- 2021
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14. Sífilis: manifestaciones orales, revisión sistemática
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Apoita Sanz, M, primary, González Navarro, B, additional, Jané-Salas, E, additional, Marí Roig, A, additional, Estrugo Devesa, A, additional, and López-López, J, additional
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- 2020
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15. Apical periodontitis and glycemic control in type 2 diabetic patients: Cross-sectional study
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Pérez-Losada, Fd., primary, López-López, J., additional, Martín-González, J., additional, Jané-Salas, E., additional, Segura-Egea, JJ., additional, and Estrugo-Devesa, A., additional
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- 2020
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16. Role of selected salivary inflammatory cytokines in the diagnosis and prognosis of oral squamous cell carcinoma. A Systematic Review and Meta-analysis
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Benito-Ramal, E., primary, Egido-Moreno, S., additional, González-Navarro, B., additional, Jané-Salas, E., additional, Roselló-Llabrés, X., additional, and López-López, J., additional
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- 2020
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17. The Importance of Flap Design in Third Molar Surgery: A systematic Review
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García Ortiz de Zárate F, Izquierdo Gómez K, Arranz Obispo C, López López J, Jané Salas E, and González Navarro B
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business.industry ,medicine.medical_treatment ,Dentistry ,030206 dentistry ,General Medicine ,Dehiscence ,Trismus ,03 medical and health sciences ,0302 clinical medicine ,Third molar surgery ,medicine ,030212 general & internal medicine ,medicine.symptom ,Ostectomy ,business - Published
- 2018
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18. Fractura mandibular tardía post exodoncia de molares inferiores. Caso clínico
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Olivera Oliva, A, primary, Farnés Montpeyó, M, additional, Estrugo Devesa, A, additional, Jané Salas, E, additional, Arranz Obispo, C, additional, Marí Roig, A, additional, and López-López, J, additional
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- 2019
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19. Factores asociados a la malignización del liquen plano oral. Revisión de la literatura
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Asensi Anta, E, primary, Sardañés Martínez, S, additional, Izquierdo Gómez, K, additional, Jané Salas, E, additional, Estrugo Debesa, A, additional, and López López, J, additional
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- 2019
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20. Relationship between metabolic syndrome and oral/dental patology
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Gonzalez Navarro, B., primary, Jané Salas, E., additional, López López, J., additional, Rodriguez Sánchez, A., additional, Corbella, X., additional, and Pintó Sala, X., additional
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- 2018
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21. Osteomyelitis of the jaw (with pathological fracture) following extraction of an impacted wisdom tooth. A case report
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González-Navarro, B., primary, Arranz-Obispo, C., additional, Albuquerque, R., additional, Jané-Salas, E., additional, and López-López, J., additional
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- 2017
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22. Chitosán más clorhexidina (Bexident®Post) en el control del dolor y la inflamación posoperatoria en implantología oral: estudio piloto
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López López, J., Jané Pallí, E., Princep Arisó, C., Ayuso Montero, R., Estrugo Devesa, A., and Jané Salas, E.
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bexident®post ,Chitosán ,clorhexidina ,chlorhexidine ,implants ,Implantes ,cirugía oral ,oral surgery - Abstract
Objetivos: Evaluación de la eficacia del chitosán más la clorhexidina en el control del dolor y la inflamación posoperatoria en cirugía implantológica oral. Material y métodos: Es un estudio clínico piloto prospectivo en pacientes a los que se les colocan implantes. A todos los pacientes se les pauta después de la cirugía Bexident®Post en gel, tres veces al día durante siete días. Se valora la inflamación, la apertura bucal, el nivel de dolor, el grado de cicatrización y la opinión sobre el producto. Resultados: Se han colocado 138 implantes en 54 pacientes. El 64% eran varones y la media de tiempo quirúrgico fue de 76 minutos. La inflamación y apertura bucal pre y postoperatoria no es significativa con una p=0,000. Se han consumido 11 unidades analgésicas de media en los 7 días del posoperatorio. El EVA ha sido de 3,0 (DS= 2,0) a las 6 horas, 2,0 (DS= 2,0) a las 24 horas, 2,02 (DS= 1,0) el segundo día, 1,0 (DS= 1,0) el tercer y cuarto día y 0,0 el quinto, sexto y séptimo día. El grado de cicatrización es bueno en el 88,9% (48 pacientes); regular, en el 7,4% (4 pacientes) y malo, en el 3,7% (2 pacientes). 45 pacientes (83,3%) responden positivamente a todas las preguntas referentes al producto. Conclusiones: El producto se muestra fácil de usar, el sabor es adecuado y en este estudio la inflamación, el dolor y el consumo de medicamentos han sido mínimos. Objectives: Evaluation of the effectiveness of chitosán and chlorhexidine in controlling postoperative pain and inflammation in oral implant surgery. Material and methods: A prospective pilot clinical study in patients with implants. Bexident®Post gel are prescribed three times a day during 7 days to all patients. Inflammation, bucal opening, level of pain, degree of healing and opinion about the product are valued. Results: 138 implants were placed in 54 patients. 64% were males and the mean operative time was 76 minutes. The inflammation, pre and post-operative mouth opening are not significant at p= 0.000. 11 analgesic units have been consumed on average during 7 days of post-operative. The EVA was 3.0 (SD= 2.0) at 6 hours, 2.0 (SD= 2.0) at 24 hours, 2.02 (SD= 1.0) the second day, 1.0 (SD= 1.0) the third and fourth day and 0.0 the fifth, sixth and seventh day. The degree of healing is good in 88.9% (48 patients), fair in 7.4% (4 patients) and bad in 3.7% (2 patients). 45 patients (83%) respond positively to al questions regarding the product. Conclusions: The product is shown as easy to use, the taste is right and in this study, inflammation, pain and medicine use have been minimal. Double-blind study is needed in order to evaluate its effectiveness.
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- 2015
23. El diagnóstico del cáncer oral en el paciente geriátrico
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Jané Salas, E., Jané Pallí, E., Estrugo Devesa, A., Roselló Llabrés, X., and López-López, J.
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precancer ,Cáncer ,paciente geriátrico ,geriatric patient ,diagnóstico precoz ,precáncer ,Cancer ,early diagnosis - Abstract
El cáncer oral es una patología frecuente y creciente en el mundo occidental, su incidencia se incrementa año tras año, a pesar de que su localización, en una cavidad fácilmente accesible y explorable permitiría un diagnóstico temprano del mismo, o de las alteraciones potencialmente malignas. Las cifras de nuestro país sitúan una incidencia de 6,7 casos nuevos al año por 100.000 habitantes, con una proporción hombre/mujer de 3 a 1. La proporción de estas neoplasias aumenta de forma gradual con la edad, la posibilidad de que una lesión ulcerosa o proliferativa de cavidad oral, sea un carcinoma es mucho más elevada en pacientes mayores de 65 años. Es nuestra obligación el concienciar a nuestros pacientes, en el cese de hábitos nocivos y en la educación para establecer de la autoexploración una actividad habitual. Sin duda, una exhaustiva exploración física es la primera medida diagnóstica que poseemos asociada ante la mínima sospecha a la realización de una biopsia y el correspondiente estudio histopatológico, que puede establecer la potencialidad maligna de la lesión, así como la evolución de la misma. Disponemos, en la actualidad, de métodos complementarios de diagnósticos, que desde los tradicionales colorantes vitales, pasando por métodos ópticos, hasta la utilización de novedosas técnicas de identificación de receptores moleculares, de alteraciones cromosómicas podrían ser de utilidad en la orientación de factores de riesgo en pacientes predispuestos a padecer la patología, todo ello con el futuro puesto en identificar todos estos riesgos potenciales con un simple análisis de saliva. Lo cierto es que a día de hoy el mejor diagnóstico es la prevención y en el peor de los casos realizarlo lo más precozmente posible para mejorar las perspectivas vitales y la calidad de vida de nuestros pacientes. Oral cancer is a common and growing in the Western world disease, its incidence is increasing year after year, despite its location in an easily accessible and searchable cavity allow early diagnosis thereof, or of potentially malignant disorders. The figures of our country placed an incidence of 6.7 new cases per year per 100,000 population, with a male /female ratio of 3 to 1. It is our duty to educate our patients in the cessation of harmful habits and the Education to establish how to examine a common activity. Definitely a thorough physical examination is the first diagnostic measure we have associated under suspicion for a biopsy and the corresponding histopathology, you can set the malignant potential of the lesion, and the evolution of it. We currently have complementary diagnostic methods, which based from traditional vital dyes, through optical methods, to the use of novel techniques for identifying molecular receptors, chromosomal alterations could be useful in guiding risk factors Patients predisposed to the disease, all in the future on identifying these potential risks with a simple analysis of saliva. The truth is that today the best diagnosis is prevention and the worst do it as early as possible to improve the life prospects and quality of life of our patients.
- Published
- 2015
24. Adherencia bacteriana en los materiales de sutura de uso habitual en cirugía bucal. Revision sistemática.
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Pedregosa, D. Benito, Jané-Salas, E., Estrugo-Devesa, A., Arisó, C. Princep, Vicente, J. Moreno, Roig, A. Marí, and López-López, J.
- Abstract
Copyright of Avances en Odontoestomatologia is the property of Ediciones Avances SL and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
- Published
- 2020
- Full Text
- View/download PDF
25. Etiopatogenia de la halitosis: revisión
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López López, J., Otero Rey, E., Estrugo Devesa, A., and Jané Salas, E.
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Etiopatogenia ,halitosis ,Pathogenesis - Abstract
La halitosis o mal aliento es un problema importante dado que puede comprometer la vida de relación de las personas. Es frecuente que se atribuya el origen al estómago o a problemas nasales o pulmonares. No obstante, sabemos que hasta en el 90% de los casos, el origen se encuentra en la cavidad oral, y de forma preponderante debido al acúmulo de placa en el dorso lingual "cubierta lingual". La enfermedad periodontal también está directamente relacionada con el mal aliento, de manera que el acumulo de placa, bolsas y/o sangrado son aspectos directamente relacionados con el problema. Desde el punto de vista patogénico, las proteínas de la dieta, las de las bacterias y las de los propios tejidos de la boca, son degradadas por la acción de las proteasas bacterianas hasta aminoácidos. Los aminoácidos ricos en azufre son los máximos responsables del mal aliento. De hecho los tres productos más directamente relacionados son el sulfuro de hidrógeno, el metil mercaptano y el dimetil sulfuro. En la presente revisión repasamos todos estos aspectos y las causas más directamente relacionadas con el problema, revisando igualmente el concepto de halitofobia y pseudohalitosis. Halitosis, or bad breath is a major problem because it can compromise the people relationship life. Often origin is attributed to stomach or nasal or lung problems. However, we know that up to 90 % of cases, the source is in the oral cavity, and so dominant due to the accumulation of plaque on the dorsum of the tongue "cover tongue". Periodontal disease is also directly related to bad breath, so that the accumulation of plaque, periodontal pockets and/or bleeding are aspects directly related to the problem. From the pathogenic point of view, the dietary and bacteria proteins, and the own oral tissues proteins, are degraded by the action of bacterial proteases to amino acids. Rich in sulfur amino acids are the maximum responsible of bad breath. In fact the three most closely related products are hydrogen sulfide, methyl mercaptan and dimethyl sulphide. In this update, we review all these aspects and causes more directly related to the problem, also reviewing the pseudohalitosis and halitophobia concepts.
- Published
- 2014
26. Tratamiento de la boca seca: nuevas tendencias
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Jané Salas, E., Estrugo Devesa, A., Ayuso Montero, R., and López López, J.
- Subjects
Tratamiento de la boca seca ,Dry mouth treatment ,boca seca ,dry mouth - Abstract
La disminución de saliva afecta la calidad de vida de los pacientes, que pueden mejorar cambiando ciertos hábitos de salud general como hidratación, uso de humidificadores ambientales, evitar tóxicos y conductas saludables, incluyendo visitas frecuentes al dentista. La prevención en los pacientes que van a ser irradiados, la modificación de los fármacos xerostomizantes en los casos posibles contribuyen al bienestar de estos pacientes. Los diferentes métodos de estimulación salivar tanto farmacológicos (ácidos, pilocarpina) como no farmacológicos (mecánicos, eléctricos, láser, acupuntura u oxígeno hiperbárico) y el uso de sustitutos salivales ayudan a mantener mejor hidratación bucal. En el futuro, el desarrollo de componentes orgánicos a partir de células madre será probablemente una posibilidad de tratamiento efectiva. Decreased saliva affects patients quality of life, that can improve changing certain health habits like hydration, usin groom humidifiers, avoid toxics and healthy behaviors, including frequent visits to the dentist. Prevention in patients who are going to be irradiated and modify xerostomizing drugs where possible contribute to the welfare of these patients. Different salivary stimulation methods, both pharmacological (acid, pilocarpine) and non-pharmacological (mechanical, electrical, laser, acupuncture or hyperbaric oxygen) and the use of salivary substitutes help maintain oral moisture better. In the future, the development of organic components from stem cells will probably be a valid line of treatment.
- Published
- 2014
27. Halitosis: diagnóstico y tratamiento
- Author
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Monfort Codinach, M. and Jané Salas, E.
- Subjects
tratamiento ,treatment ,diagnosis ,compuestos volátiles sulfurados ,Halitosis ,volatile sulfur compounds ,diagnóstico - Abstract
Introducción: Debido a los múltiples factores que pueden causar o agravar la halitosis, y que el tratamiento depende de eso, es imprescindible hacer un diagnóstico detallado para identificar todos y cada uno de ellos. Diagnóstico: En la halitosis es esencial hacer un diagnóstico etiológico. Por ello hay que prestar atención a la anamnesis para poder descartar las pocas probabilidades de una causa sistémica, preguntar al paciente sobre diferentes aspectos de la halitosis, fijándose en los aspectos psicológicos de la patología, realizar una minuciosa exploración oral y las pruebas complementarias. Tratamiento: Debemos enfocarlo según la etiología y los objetivos perseguidos son reducir el número de bacterias, el número de sustratos proteicos y neutralizar los compuestos volátiles sulfurados. Conclusiones: Es básico el correcto diagnóstico etiológico para realizar un tratamiento exitoso. Para esto el control mecánico de la placa es necesario pero no suficiente, considerando los posibles efectos adversos de los agentes químicos por la larga duración de los tratamientos. Introduction: Due to the many factors that can cause or aggravate halitosis, and considering that treatment depends on it, it is essential to make a detailed diagnosis to identify each and every one of them. Diagnosis: Is essential to do an etiological diagnosis. Therefore we must pay attention to the anamnesis to rule out the few chances of a systemic cause, ask the patient about different aspects of halitosis, looking at the psychological aspects of the disease, a thorough oral examination and complementary tests. Conclusions: It is basic the correct etiological diagnosis to successful treatment. For this, mechanical plaque control is necessary but not enough, considering the possible adverse effects of chemical agents by the long duration of treatment.
- Published
- 2014
28. Caninos incluidos, tratamiento odontológico: Revisión de la literatura
- Author
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Egido Moreno, S., Arnau Matas, C., Juárez Escalona, I., Jané-Salas, E., Marí Roig, A., and López-López, J.
- Subjects
ortodóncico y quirúrgico ,tratamiento ,treatment ,incluido ,Canino ,impacted ,orthodontic and surgical ,Canine - Abstract
El objetivo de este trabajo es realizar una revisión bibliográfica de los últimos 5 años (2006-2011), sobre la situación actual de los caninos incluidos y su tratamiento. Se ha analizado la incidencia, etiología, diagnóstico y factores pronósticos de su alineamiento, así como las terapéuticas de los mismos. Su manejo es de especial importancia, ya que estos dientes tienen un papel fundamental en la apariencia facial, estética dental, desarrollo del arco dental y la oclusión funcional. Se deben diagnosticar mediante una evaluación clínica y radiológica minuciosa además de un examen radiográfico; determinando las posibles complicaciones asociadas y las opciones de tratamiento individualizándolas en cada caso. Se han planteado diferentes formas de manejarlos que van desde los controles periódicos, la prevención de la inclusión con el tratamiento interceptivo, el tratamiento ortodóncico-quirúrgico o la extracción. Antes de iniciar cualquier procedimiento debemos valorar las características individuales de cada paciente, así como la situación y la inclinación del diente para lograr nuestro objetivo. The aim of this article is to make a bibliographical review, from studies performed in the last 5 years (2006-2011), to analyse the current trends of the unerupted canines in its epidemiology, aetiology, diagnostic methods, prognostic factors in their alignment; and the various treatment options available. It is especially important because of its relevance in the facial appearance, dental aesthetics and functional occlusion. The diagnosis of the unerupted canine should be made through a thorough clinical and radiographic examination, because it helps in determining the best treatment plan and prevention and/or evaluation of possible complications. Different ways to manage such cases have been suggested from periodic controls, preventing the impaction using interceptive treatment, surgical and orthodontic techniques, and lastly, extraction. Thus, before commencing with any treatment, a proper evaluation of the patient characteristics and the characteristics of the canine should be evaluated to achieve the best possible outcome.
- Published
- 2013
29. Osteonecrosis de maxilares asociada al uso de bifosfonatos: Revisión de 491 casos
- Author
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Hernández Vigueras, S., Jané-Salas, E., Pérez Tomas, R., and López-López, J.
- Subjects
jaw ,Osteonecrosis ,bifosfonatos ,bisphophonates ,maxilares - Abstract
En los últimos años, el número de pacientes que presenta osteonecrosis maxilar asociada al uso de bifosfonatos (BIONJ) se ha incrementado. Esto es debido al aumento en el consumo de bifosfonatos, los cuales se asocian al tratamiento de carcinomas con metástasis óseas, mieloma múltiple, osteoporosis, osteopenia y enfermedades metabólicas como la enfermedad de Paget. Objetivo: Analizar el número de casos de pacientes que han desarrollado osteonecrosis de maxilares asociado al uso de bifosfonatos, publicados desde Junio del año 2006 hasta Abril 2010. Método: En esta revisión, se consultaron las bases de datos Pubmed-Medline, Scielo e Índice Médico Español, incluyendo límites en la búsqueda, para recopilar los casos de BIONJ que se hayan publicado desde el año 2006 hasta la actualidad. Los artículos seleccionados presentaban casos, en los cuales los pacientes que recibían bifosfonatos desarrollaban BIONJ. Resultados: Se encontraron 491 casos de BIONJ en total, de ellos 49,3% eran mujeres, 32% hombres y 18,7% no se establecía el género. La mayoría de estos casos se presentaron en la mandíbula y asociados particularmente al ácido zolendrónico. Conclusiones: En los próximos años se espera que el número de pacientes que desarrollen esta complicación vaya en aumento, en particular en mujeres, a las cuales se les indica cada vez más esta medicación para el tratamiento de la osteoporosis. In the last years, the number of patients presenting jaw osteonecrosis associated with the use of bisphosphonates (BIONJ) has increased. This is due to increased consumption of bisphosphonates, which are associated with the treatment of carcinomas with bone metastases, multiple myeloma, osteoporosis, osteopenia and metabolic diseases such as Paget´s disease. The aim of this review is to analyze the number of cases of patients who developed jaws osteonecrosis-associated with the use of bisphosphonates, published from June 2006 to April 2010. In this review, we referred to the databases Pubmed-Medline, Scielo and Spanish Medical Index, including limits on the search to collect BIONJ cases published from 2006 up to now. The selected papers presented cases in which the patients who received bisphosphonates developed BIONJ. We found 491 cases of BIONJ in total, of which 49.3% correspond to women, 32% to men and 18.7%, did not establish gender. Most of these cases occurred in the mandible and associated particularly with zoledronic acid. In the coming years it is expected that the number of patients who develop this complication increase, particularly in women, who are more and more prescribed this medication for the osteoporosis treatment.
- Published
- 2012
30. Chitosán más clorhexidina (Bexident®Post) en el control del dolor y la inflamación posoperatoria en implantología oral: estudio piloto
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López López, J., primary, Jané Pallí, E., additional, Princep Arisó, C., additional, Ayuso Montero, R., additional, Estrugo Devesa, A., additional, and Jané Salas, E., additional
- Published
- 2015
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31. El diagnóstico del cáncer oral en el paciente geriátrico
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Jané Salas, E., primary, Jané Pallí, E., additional, Estrugo Devesa, A., additional, Roselló Llabrés, X., additional, and López-López, J., additional
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- 2015
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32. Efecto de los tratamientos antirretrovirales en las manifestaciones orales de los pacientes VIH+
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Jané-Salas, E., Chimenos-Küstner, E., López-López, J., Roselló-Llabrés, X., and Ocaña-Rivera, I.
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AIDS ,Sida ,manifestaciones orales ,VIH ,HIV ,tratamiento antirretroviral de alta actividad (TAAA) ,oral manifestations ,high activity antiretroviral treatment (HAART) - Abstract
El presente trabajo es un estudio para valorar el efecto de los tratamientos antirretrovirales en pacientes seropositivos al VIH, visitados en el dispensario de enfermedades infecciosas del Hospital Vall D´Hebron de Barcelona. Se visitaron 90 pacientes, 51 varones (56,7%) y 39 mujeres (43,3%), siendo la edad media de los pacientes de 36,2 años con una desviación de ±17,8 años y una moda de 35 años. Las visitas fueron realizadas desde enero a diciembre del año 1999. Estos pacientes recibían tratamiento antirretroviral de uno o más fármacos y algunos de ellos (32,2% ) estaban sometidos a tratamiento antirretroviral de alta actividad (TAAA). Asimismo, en estos pacientes se valoró el recuento de CD4 y carga viral de forma bimodal, al inicio del proceso y en el momento de la visita. La exploración de la cavidad oral se realizó en este momento, buscando las lesiones asociadas al Sida según la clasificación de Pindborg y cols., de 1989. La patología más prevalente encontrada en este estudio fue la sensación de boca seca o xerostomía en un 47,8%, seguida por orden de frecuencia de policaries (34,4%) y candidiasis eritematosa (31,1%). Otras manifestaciones orales son muy poco frecuentes, en comparación con los resultados de otros autores en la etapa previa a la utilización de los inhibidores de la proteasa (IP). Así, por ejemplo, se observó un solo caso de leucoplasia vellosa, tan característica antes del año 1996. We evaluate the effects of antiretroviral treatments in HIV seropositive patients, who were seen in the Clinic for Infectious Diseases in the Vall D´Hebron Hospital, Barcelona. 90 patients were seen, 51 males (56.7%) and 39 females (43.3%), the mean age of the patients was 36.2 years with a deviation of ±17.8, and a mode of 35 years. The visits were carried out between January and December 1999. These patients were receiving antiretroviral treatment with one or more drugs and some of them (32.2%) were subjected to high activity antiretroviral treatment (HAART). Also, in these patients the CD4 count and bimodal viral load was measured, at the start of the disease process and at the time of visit. Theoral cavity was examined at this time, in search of lesions associated with AIDS according to the classification by Pindborg et al, 1989. The most prevalent pathology found in this study was the sensation of dry mouth or xerostomia in 47.8%, followed by, in order of frequency, multiple caries (34.4%) and erythematous candidiasis (31.1%). Other oral manifestations are very rare, in comparison with the results of other authors in the time before the use of protease inhibitors (PI). There is, for example, only one case of leukoplakia, so characteristic before 1996.
- Published
- 2006
33. Tratamiento de la boca seca: nuevas tendencias
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Jané Salas, E., primary, Estrugo Devesa, A., additional, Ayuso Montero, R., additional, and López López, J., additional
- Published
- 2014
- Full Text
- View/download PDF
34. Etiopatogenia de la halitosis: revisión
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López López, J., primary, Otero Rey, E., additional, Estrugo Devesa, A., additional, and Jané Salas, E., additional
- Published
- 2014
- Full Text
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35. Halitosis: diagnóstico y tratamiento
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Monfort Codinach, M., primary and Jané Salas, E., additional
- Published
- 2014
- Full Text
- View/download PDF
36. Peripheral Giant Cell Granuloma in Edentulous Region
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Zapata-Domínguez, C., primary, Monzón-Lloret, M., additional, Schiavone-Mussano, R., additional, Jané-Salas, E., additional, Devesa-Estrugo, A., additional, and López-López, J., additional
- Published
- 2014
- Full Text
- View/download PDF
37. Caninos incluidos, tratamiento odontológico: Revisión de la literatura
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Egido Moreno, S., primary, Arnau Matas, C., additional, Juárez Escalona, I., additional, Jané-Salas, E., additional, Marí Roig, A., additional, and López-López, J., additional
- Published
- 2013
- Full Text
- View/download PDF
38. Osteonecrosis de maxilares asociada al uso de bifosfonatos: Revisión de 491 casos
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Hernández Vigueras, S., primary, Jané-Salas, E., additional, Pérez Tomas, R., additional, and López-López, J., additional
- Published
- 2012
- Full Text
- View/download PDF
39. Inferior alveolar nerve injury resulting from overextension of an endodontic sealer: non-surgical management using the GABA analogue pregabalin
- Author
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López-López, J., primary, Estrugo-Devesa, A., additional, Jané-Salas, E., additional, and Segura-Egea, J. J., additional
- Published
- 2011
- Full Text
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40. Efecto de los tratamientos antirretrovirales en las manifestaciones orales de los pacientes VIH+
- Author
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Jané-Salas, E., primary, Chimenos-Küstner, E., additional, López-López, J., additional, Roselló-Llabrés, X., additional, and Ocaña-Rivera, I., additional
- Published
- 2006
- Full Text
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41. Attitude of general dental practitioners, oral surgeons, and dentistry students towards oral lesions and oral biopsy.
- Author
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Schiavo-Di Flaviano V, González-Navarro B, Martín Carreras-Presa C, Jané-Salas E, and López-López J
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- Humans, Female, Male, Biopsy, Adult, Mouth Diseases diagnosis, Mouth Diseases pathology, Dentists, Self Report, Surgery, Oral education, Oral and Maxillofacial Surgeons, Middle Aged, Young Adult, Students, Dental, Attitude of Health Personnel
- Abstract
Background: Oral biopsy is a fundamental surgical procedure used to obtain a histopathological result that assists clinicians in establishing a definitive diagnosis of oral mucosal lesions. The aim of this study was to asses the knowledge and attitudes of dental students, general dentists, and oral surgery experts regarding the detection of oral lesions and the use of biopsy as a diagnostic tool., Material and Methods: a self-administered questionnaire consisting of 26 questions and 3 clinical cases on oral lesions was distributed to general dentists, oral surgery specialists and final-year dentistry students at the University of Barcelona. A descriptive analysis of all variables included was performed. The chi-square test was used to compare categorical variables, and a multivariate logistic regression model was performed., Results: A total of 281 questionnaires were included in the study. In terms of diagnosing of oral lesions, 44.7% of students and 32.1% of general dentists were unable to make an accurate diagnosis, compared to 81.7% of specialists. Twelve students (15.8%) and twenty general dentists (14.9%) reported lacking the skills to perform a biopsy. Ninety general dentists (67.2%) reported feeling uncomfortable performing biopsies due to a lack of experience. Oral surgeons are 84.4 times more likely to identify lesions of the oral mucosa compared to students. General dentists experience 9.6 times more difficulty diagnosing oral lesions compared to students. General dentists are 0.43 times less likely to perform sample analysis compared to students., Conclusions: Oral biopsy is a procedure primarily performed by specialists in oral surgery, with its use among general dentists being limited, likely due to a lack of training in the field. To encourage the use of biopsy among general dentists, clinical training should be a fundamental component of the education of oral healthcare providers.
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- 2025
- Full Text
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42. Prevalence and risk factors of chronic oral complications in head and neck cancer therapies: A retrospective study.
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Benito-Ramal E, Camacho-Mourelo A, González-Navarro B, López JL, and Jané-Salas E
- Subjects
- Humans, Retrospective Studies, Male, Female, Risk Factors, Middle Aged, Prevalence, Aged, Pilot Projects, Chronic Disease, Adult, Cohort Studies, Aged, 80 and over, Head and Neck Neoplasms therapy, Mouth Diseases etiology, Mouth Diseases epidemiology, Mouth Diseases therapy
- Abstract
Background: Oncological therapy can trigger various complications and side effects in certain tissues, such as the oral cavity, inducing a direct or indirect impact on basic functions and the patient's quality of life. The aim of the study is to determine the prevalence of chronic oral complications of oncological treatments in patients with head and neck cancer and assess their possible relationship with risk indicators associated with the patient, the tumor, and the treatment., Material and Methods: A retrospective, single-center, observational pilot cohort study was designed at the Dental Hospital of the University of Barcelona, involving patients with head and neck cancer who underwent surgery, non-surgical oncological therapy (radiotherapy/chemotherapy/immunotherapy), or combined therapy. Medical histories were analyzed, and data related to demographics, toxic, hygienic, and dietary habits, systemic and oral health status, characteristics of cancer and its treatment, and registered chronic oral complications were collected. The results were expressed in descriptive measures (means, standard deviations, counts, prevalence, and 95% confidence intervals), and for statistical associations, parametric and non-parametric tests were used., Results: The overall prevalence of chronic oral complications was 92.57%. Dental disease (81.14%), periodontal disease (65.14%), and hyposalivation/xerostomia (62.86%) showed the highest prevalence. Advanced age, certain cancer locations, advanced cancer stages, and oncological therapy including radiotherapy were significantly associated with the presence and number of complications., Conclusions: The elevated noticed prevalence necessitates rigorous monitoring and preventive care. The combination of risk factors can significantly contribute to oral complications. Understanding these factors services dentists establish protocols for preventing, diagnosing, and treating oncology patients.
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- 2024
- Full Text
- View/download PDF
43. Association of vitamin D levels and oral lichen planus. Systematic review and meta-analysis.
- Author
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Egido-Moreno S, Valls-Roca-Umbert J, Parra-Moreno FJ, Jané-Salas E, Blanco-Carrión A, and López-López J
- Subjects
- Humans, Vitamin D Deficiency complications, Vitamin D blood, Lichen Planus, Oral blood
- Abstract
Background: Oral lichen planus (OLP) is an inmuno-mediated mucocutaneous chronical inflammatory disease. Multiple predisposing factors are considered, such as autoimmune response, microorganisms, medications, dental materials, psychological stress, genetic predisposition or nutritional deficiencies. The deficiency of vitamin D has been related to various autoimmune diseases like OLP., Material and Methods: The electronic search was conducted in the MEDLINE (Pubmed), Scopus, Cochrane Library and Web of Science databases. To assess any potential risk of bias, the authors critically appraised each study by the Newcastle-Ottawa Scale for cohort and case-control studies. Pooled analyses were performed using a random-effects model. Heterogeneity of the studies was assessed by the I2 statistics. Forest Plots were performed to graphically represent the difference between vitamin D concentrations in the OLP compared to healthy group, with a 95% confidence interval., Results: After applying our inclusion and exclusion criteria, 7 articles were included in our review. The median concentration vitamin D in ng/ml found in serum for patients with OLP was of 26,6311,75ng/ml and for healthy patients was of 31,438,7ng/ml. Regarding the quantitative analysis, 7 studies were included. The difference in the concentration of vitamin D in healthy patients and patients with OLP statistically significant (Weighted Mean Difference (WMD): -6.20, 95% CI: -11.24 to -1.15, p=0.02 and I2 heterogeneity: 94%, p<0.00001)., Conclusions: The patients with OLP have statistically lower vitamin D levels than healthy patients.
- Published
- 2024
- Full Text
- View/download PDF
44. Role of selected salivary inflammatory cytokines in the diagnosis and prognosis of oral squamous cell carcinoma. A Systematic Review and Meta-analysis.
- Author
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Benito-Ramal E, Egido-Moreno S, González-Navarro B, Jané-Salas E, Roselló-Llabrés X, and López-López J
- Subjects
- Humans, Cytokines analysis, Tumor Necrosis Factor-alpha, Interleukin-6 analysis, Interleukin-8, Reproducibility of Results, Biomarkers, Tumor analysis, Squamous Cell Carcinoma of Head and Neck, Prognosis, Saliva chemistry, Carcinoma, Squamous Cell diagnosis, Carcinoma, Squamous Cell pathology, Mouth Neoplasms diagnosis, Mouth Neoplasms pathology, Head and Neck Neoplasms
- Abstract
Background: Oral squamous cell carcinoma (OSCC) is gradually increasing its incidence in our society. Unfortunately, this entity is diagnosed at an advanced stage in most patients, a fact that implies greater difficulty in its treatment and a worse prognosis. This systematic review aims to assess whether the cytokines IL-6, IL-8 and TNF-α are potential salivary biomarkers that allow early diagnosis of cancer., Material and Methods: An electronic search was performed in three databases (Pubmed, Scopus and Web of Science). We used the following keywords: "salivary cytokines", "saliva cytokines", "salivary interleukins", "biomarkers", "oral squamous cell carcinoma" and "diagnosis", combined with the Boolean operators "AND" and "OR"., Results: 128 publications were found and finally 23 articles were included in the review and 15 in the meta-analysis. It has been observed that the majority of OSCC patients express higher salivary concentrations of IL-6, IL-8 and TNF-α compared to the control (CL) and premalignant lesion (OPML) groups. It has also been observed that the different premalignant lesions do not have statistically significant differences in the salivary concentration of the cytokines, and on the other hand, differences have been observed between the different TNM stages. The meta-analysis has shown that the difference in concentration of IL-6, IL-8 and TNF-α is statistically significant between the CL group and the OSCC, and also between the CL group and OPML., Conclusions: There is sufficient evidence to affirm that IL-6, IL-8 and TNF-α are useful salivary cytokines in the early diagnosis and prognosis of OSCC. Although future studies are necessary to establish greater reliability of these biomarkers and thus be able to develop a valid diagnostic test.
- Published
- 2023
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- View/download PDF
45. Association between the Mediterranean Diet and Vitamin C and the Risk of Head and Neck Cancer.
- Author
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Saka-Herrán C, Pereira-Riveros T, Jané-Salas E, and López-López J
- Subjects
- Humans, Ascorbic Acid, Antioxidants, Case-Control Studies, Risk Factors, Vitamins, Diet, Mediterranean, Head and Neck Neoplasms epidemiology, Head and Neck Neoplasms prevention & control
- Abstract
Diet may modulate the risk of head and neck cancer (HNC) through antioxidant and anti-inflammatory effects. To date, there is limited evidence regarding the effects of the Mediterranean diet on HNC risk. The purpose of the study was to assess the association between Mediterranean diet adherence, type of diet, and vitamin C and the risk of HNC. A case-control study was conducted at the Dentistry Hospital, University of Barcelona, including 101 cases of HNC and 101 controls matched by age and sex. Dietary habits were assessed using a 14-question Mediterranean diet score that classified the type of diet into healthy diet (10-14 points), regular diet (5-9 points), and unhealthy diet (≤4 points). Multivariate logistic regression models were used to assess the association between Mediterranean diet adherence, type of diet, and vitamin C and the risk of HNC. Higher adherence to the Mediterranean diet was significantly associated with a lower risk of HNC (OR = 0.88, 95% CI: 0.79-0.98). A healthy diet (OR = 0.29, 95% CI: 0.10-0.84) and vitamin C intake (OR = 0.25, 95% CI: 0.10-0.62) were strongly associated with lower odds of HNC. Moderate egg intake was the only type of food significantly associated with a lower risk of HNC. Dietary patterns that emphasize a high intake of antioxidant and anti-inflammatory bioactive components may have a protective effect on the risk of HNC.
- Published
- 2023
- Full Text
- View/download PDF
46. Effects of the Prior Use of Statins on Head and Neck Cancer Risk: A Hospital-Based Case-Control Study.
- Author
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Saka-Herrán C, Jané-Salas E, Mano-Azul A, Torrejón-Moya A, Estrugo-Devesa A, and López-López J
- Abstract
Mechanisms related to the potential beneficial effects of statins on cancer are mainly related to the inhibition of the mevalonate pathway. The purpose of this study was to assess the association between prior use of statins and the risk of head and neck cancer. A hospital-based case-control study was conducted at the Dentistry Hospital of the University of Barcelona, including 101 incident cases of head and neck cancer and 101 controls matched to cases by age and sex. Multivariate logistic regression models were used to assess the association between prior statin exposure and head and neck cancer risk. Of the 202 patients included in total, 28.2% had previously received prescriptions for statins. Prior use of statins was found in 25.7% of cases and 30.7% of controls. Exposure to statins was not associated with head and neck cancer risk (OR = 0.72; 95% CI 0.28-1.84; p = 0.49). There was also no time- or dose-dependent association. Similar trends were observed when analyzed by subsites of cancer and recurrence rate. Our findings do not support a beneficial effect of prior statin exposure on head and neck cancer risk. Future research relying on observational data should emulate randomized clinical trials before clinical implications for repurposing drugs can be drawn.
- Published
- 2022
- Full Text
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47. Frequency and type of digital procedures used for the intraoral prosthetic rehabilitation of patients with head and neck cancer: A systematic review.
- Author
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Moreno Soriano C, Castañeda Vega P, Estrugo Devesa A, Jané Salas E, and López López J
- Subjects
- Computer-Aided Design, Dental Prosthesis Design methods, Humans, Workflow, Dental Implants, Head and Neck Neoplasms
- Abstract
Statement of Problem: In spite of a digital workflow playing an important role in the intraoral prosthetic rehabilitation of patients with head and neck cancer, information about how it has been implemented and its clinical implications is sparse., Purpose: The purpose of this systematic review was to evaluate the use of a digital workflow in the intraoral prosthetic rehabilitation of patients with head and neck cancer by analyzing the frequency and type of the digital procedures used., Material and Methods: Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines were followed. The following terms were applied for the search conducted in the MEDLINE-PubMed, Cochrane, and SciELO databases: (prosthesis OR dental OR rehabilitation) AND (digital OR CAD-CAM OR intraoral scanner) AND (Cancer OR head neck). Articles that specified data on intraoral prosthetic treatment and analyzed the use of a digital workflow in the different prosthetic phases such as digital scanning and computer-aided design and computer-aided manufacturing (CAD-CAM) in patients with head and neck cancer were included. Data from the frequency and type of digital procedures were analyzed., Results: Thirteen articles were included, and all had incorporated CAD-CAM techniques in at least 1 of the prosthetic treatment stages (scanning, design, and/or fabrication). Only 1 patient was rehabilitated by using a completely digital workflow. The most frequent prosthetic treatment was an obturator (82.6%). Regarding the image capture method, the most used method was cone beam computed tomography (CBCT) (60.9%)., Conclusions: Most reports described the partial use of a digital workflow in the intraoral prosthetic rehabilitation of patients treated for head and neck cancer. A digital workflow is used for specific stages but not for the entire process. More studies are needed to evaluate digital systems, ideally comparing parameters with the conventional method, and to determine whether this technique has more relevant clinical implications., (Copyright © 2020 Editorial Council for the Journal of Prosthetic Dentistry. Published by Elsevier Inc. All rights reserved.)
- Published
- 2022
- Full Text
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48. Patients with Thyroid Disorder, a Contraindication for Dental Implants? A Systematic Review.
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Torrejon-Moya A, Izquierdo-Gómez K, Pérez-Sayáns M, Jané-Salas E, Marí Roig A, and López-López J
- Abstract
The thyroid gland is composed of the thyroid follicles, considered to be the functional units of the thyroid gland. The synthesis of the thyroid hormones occurs in these follicles. Triiodothyronine (T3) and thyroxine (T4) are the thyroid hormones and affect metabolic processes all through the body. This systematic evaluation was performed to answer the following PICO question: "Can patients with thyroid disorders undergo dental implant rehabilitation with the same survival rate as patients without thyroid disorders?". A systematic review of the literature was conducted following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) statements to gather available and current evidence of thyroid disorders and its relationship with dental implants. The electronic search, in the PubMed and Cochrane databases, yielded 22 articles. Out of the 22 articles, only 11 fulfilled the inclusion criteria. Manual research of the reference list yielded no additional papers. According to the SORT criteria and answering our PICO question, level B can be established to conclude that patients with thyroid disorders can be rehabilitated with dental implants, with similar survival rates as patients without thyroid disorders. Papers with higher scientific evidence and bigger sample size should be carried out.
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- 2022
- Full Text
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49. SARS-CoV-2 oral-associated lesions: Discussion of elicited response.
- Author
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Martín Carreras-Presas C, Amaro Sánchez J, López-Sánchez AF, Jané-Salas E, and Somacarrera Pérez ML
- Subjects
- Humans, Membrane Glycoproteins, COVID-19, SARS-CoV-2
- Published
- 2022
- Full Text
- View/download PDF
50. The Application of Beta-Tricalcium Phosphate in Implant Dentistry: A Systematic Evaluation of Clinical Studies.
- Author
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Roca-Millan E, Jané-Salas E, Marí-Roig A, Jiménez-Guerra Á, Ortiz-García I, Velasco-Ortega E, López-López J, and Monsalve-Guil L
- Abstract
The demand for synthetic graft materials in implant dentistry is rising. This systematic review aims to evaluate the survival rate of dental implants placed simultaneously with bone regeneration procedures using the material β-tricalcium phosphate, one of the most promising synthetic graft materials. The electronic search was conducted in PubMed, Scielo, and the Cochrane Central Register of Controlled Trials. Five randomized clinical trials, one non-randomized controlled clinical trial and four observational studies without control group were include. Implant survival rate and other clinical, radiographic, and histological parameters did not differ from those of implants placed simultaneously with another type of graft material, or placed in blood clots or natural alveolar ridges. Based on the available literature, β-tricalcium phosphate seems to be a promising graft material in implant dentistry. Nevertheless, more randomized clinical trials, with long follow-up periods, preoperative and postoperative CBCT, and histological analysis, are necessary to assess its long-term behavior.
- Published
- 2022
- Full Text
- View/download PDF
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