182 results on '"Jamieson, Andrew G."'
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2. Mechanism of Crosstalk between the LSD1 Demethylase and HDAC1 Deacetylase in the CoREST Complex
3. Friends or Foes? Emerging Impacts of Biological Toxins
4. Hydroxamic Acid-Modified Peptide Library Provides Insights into the Molecular Basis for the Substrate Selectivity of HDAC Corepressor Complexes
5. Investigation of a new substrate directed aza-Claisen rearrangement for natural product synthesis
6. Rotamer-Controlled Dual Emissive α-Amino Acids
7. Structural basis for DNA damage-induced phosphoregulation of MDM2 RING domain
8. Development of Bifunctional, Raman Active Diyne‐Girder Stapled α‐Helical Peptides**
9. A heme-binding domain controls regulation of ATP-dependent potassium channels
10. Insights into the Recruitment of Class IIa Histone Deacetylases (HDACs) to the SMRT/NCoR Transcriptional Repression Complex
11. Hydrogen-Bonded Synthetic Mimics of Protein Secondary Structure as Disruptors of Protein-Protein Interactions
12. Investigating the Structure–Activity Relationship of 1,2,4-Triazine G-Protein-Coupled Receptor 84 (GPR84) Antagonists
13. A novel dihydro-pyrazolo(3,4d)(1,2,4)triazolo(1,5a)pyrimidin-4-one (AJ23) is an antagonist at adenosine A1 receptors and enhances consolidation of step-down avoidance
14. Stapled ACE2 peptidomimetics designed to target the SARS-CoV-2 spike protein do not prevent virus internalisation
15. Peptides derived from the SARS-CoV-2 receptor binding motif bind to ACE2 but do not block ACE2-mediated host cell entry or pro-inflammatory cytokine induction
16. Ether-directed palladium(II)-catalysed aza-Claisen rearrangements: studies on the origin of the directing effect
17. Emerging peptide science in the United Kingdom
18. Peptide Scanning for Studying Structure-Activity Relationships in Drug Discovery
19. Hydrogen-Bonded Synthetic Mimics of Protein Secondary Structure as Disruptors of Protein-Protein Interactions
20. μ‐Conotoxin KIIIA peptidomimetics that block human voltage‐gated sodium channels
21. Development of Potent PfCLK3 Inhibitors Based on TCMDC-135051 as a New Class of Antimalarials
22. Conformationally rigid pyrazoloquinazoline α-amino acids: one- and two-photon induced fluorescence
23. Structure–Activity Analysis of the Growth Hormone Secretagogue GHRP-6 by α- and β-Amino γ-Lactam Positional Scanning
24. Synthesis of HDAC substrate peptidomimetic inhibitors (SPIs) using Fmoc amino acids incorporating zinc-binding groups
25. Validation of the protein kinase Pf CLK3 as a multistage cross-species malarial drug target
26. Synthesis of HDAC Substrate Peptidomimetic Inhibitors Using Fmoc Amino Acids Incorporating Zinc-Binding Groups
27. Stapled Peptides as Potential Therapeutics
28. Synthesis and Fluorescent Properties of β-Pyridyl α-Amino Acids
29. α-Conotoxin GI triazole-peptidomimetics: potent and stable blockers of a human acetylcholine receptor
30. μ‐Conotoxin KIIIA peptidomimetics that block human voltage‐gated sodium channels.
31. A short peptide that preferentially binds c-MYC G-quadruplex DNA.
32. Validation of the protein kinase PfCLK3 as a multi-stage cross species malarial drug target
33. Enzymatically-stable oxetane-based dipeptide hydrogels
34. Lipopeptidomimetics derived from teixobactin have potent antibacterial activity against Staphylococcus aureus
35. Insights into the activation mechanism of class I HDAC complexes by inositol phosphates
36. Positional scanning for peptide secondary structure by systematic solid-phase synthesis of amino lactam peptides
37. Solid-Phase Synthesis of Oxetane Modified Peptides
38. Urotensin-II peptidomimetic incorporating a non-reducible 1,5-triazole disulfide bond reveals a pseudo-irreversible covalent binding mechanism to the urotensin G-protein coupled receptor
39. Synthesis of HDAC Substrate Peptidomimetic Inhibitors Using Fmoc Amino Acids Incorporating Zinc-Binding Groups.
40. A TPX2 Proteomimetic Has Enhanced Affinity for Aurora-A Due to Hydrocarbon Stapling of a Helix
41. The ansamycin antibiotic, rifamycin SV, inhibits BCL6 transcriptional repression and forms a complex with the BCL6-BTB/POZ domain
42. The Ansamycin Antibiotic, Rifamycin SV, Inhibits BCL6 Transcriptional Repression and Forms a Complex with the BCL6-BTB/POZ Domain
43. Robust asymmetric synthesis of unnatural alkenyl amino acids for conformationally constrained α-helix peptides
44. Investigation of a new substrate directed aza-Claisen rearrangement for natural product synthesis
45. Peptide Scanning for Studying Structure-Activity Relationships in Drug Discovery
46. A 1,3-phenyl-linked hydantoin oligomer scaffold as a β-strand mimetic
47. α-Amino-β-hydroxy-γ-lactam for Constraining Peptide Ser and Thr Residue Conformation
48. StructureâActivity Analysis of the Growth Hormone Secretagogue GHRP-6 by α- and β-Amino γ-Lactam Positional Scanning
49. Insertion of multiple α‐amino γ‐lactam (Agl) residues into a peptide sequence by solid‐phase synthesis on synphase lanterns
50. Ether‐Directed, Stereoselective Aza‐Claisen Rearrangements: Synthesis of the Piperidine Alkaloid, α‐Conhydrine (I).
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