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Key Clinical Message Early intervention is imperative for potentially fatal dermatologic diseases such as pemphigus vulgaris. In rural Nepal, limited public awareness, home remedies, and delays in healthcare access lead to poor outcomes. Although biopsy confirms the diagnosis, experienced dermatologists can make an accurate clinical diagnosis when characteristic skin lesions are present.

Introduction: Skin diseases are common in children; however they differ depending in age, region, socioeconomic status and climate. Many studies have been done to study pattern of dermatological disease in pediatric age group but only few studies have been done in its seasonal variation. So we decided to study seasonal variation of pediatric dermatoses. Methods: This was retrospective study done from hospital record of Lumbini Medical College Teaching Hospital (LMCTH). All children 14 years and below attending the Dermatology out-patient clinic with skin diseases between the period of March 2015 to February 2016 were included. Demographic, clinical and laboratory details were recorded. Data were collected and categorized according to four seasons. Microsoft Excel was used for data entry while all analysis, both descriptive and inferential, was done using SPSS version 22. Results: There were a total of 987 children visiting Dermatology clinic during the study period. Of those, 520 (52.7%) were male and the remaining 467 (47.3%) were female with M:F ratio of 1.1:1. Most of the disorders were seen between 10-14 years of age. Majority of visits was in summer (n=403, 40.8%) followed by spring, autumn and winter. Most common dermatosis seen among children during summer was fungal infection (n=91, 9.2%) and during winter was eczema (n=49, 5%). Conclusion: In the present setting there is seasonal variation of dermatological diseases in pediatric age group.

Introduction: The pattern of skin disease differs in different countries, and within various region of a country depending on socio-economic, racial and environmental factors. Many researchers have reported various patterns of skin disease in different countries. This type of study has not been done in this part of country. So, we decided to study, assess and compare the different pattern of dermatological disease in patients visiting our centre. Methods: This was retrospective study done from the hospital record of Lumbini Medical College Teaching Hospital (LMCTH). The study was carried out from September 2014 to December 2014 while the data were accessed from the records of respondents from September 2013 to August 2014. The diagnosis was categorized into 10 groups. The diagnosis which did not fit any category was kept in "Others". The 10 categories include acne, bacterial infection, dermatophytes, eczema, leprosy, pigmentory diseases, psoriasis, scabies, urticaria and viral infection. Data was collected based on gender and categorized according to the diagnosis. Microsoft Excel was used for data entry while all the analysis both descriptive and inferential statistics was done using SPSS version 21. Results: There were a total of 7967 patients visiting Dermatology OPD. Out of the total patient, there were 52.10% female and 47.89% male and this difference was statistically significant. In both gender eczema was the most common skin disease. Eczema was significantly more common in male whereas acne was significantly common in female. Most of the patients were from age group of 15-30 yrs with eczema being commonest in this age group. Conclusion: Eczema and dermatophytes are the most common dermatological diseases. Eczema is significantly more common in male. Acne is significantly more common in female.

Background: Psoriasis is a worldwide disease and varies in its clinical profile and epidemiology in different regions of the world. The disease is common and few epidemiological data are available in our country. Objective: The purpose of this study was to evaluate the epidemiologic and clinical features of Psoriasis in Lumbini Medical College. Methods: A retrospective investigation of a total of 240 patients visiting Out Patient Department (OPD) of Dermatology and Venereology of Lumbini Medical College with Psoriasis was done. The parameters included were age at onset of disease, age at first treatment, current age, sex, type of disease and distribution of lesions. Data and statistical analysis was done with SPSS 17.0. Results: The mean age of patients at onset of disease was 26.4 (SD = 14.3) years. M:F ratio was 1.16. Psoriasis vulgaris (PV) was the most common variety of the disease. Extensor surface of the body was most commonly involved. Conclusion: Psoriasis is a common dermatological disease accounting 2.9% of all dermatology patients in our center. PV is the most common clinical subtype. The disease is more frequent in the third decade of life and has a male predominance in our region. Treatment compliance has been found to be poor.