Search

Your search keyword '"Jaleel, Mambarambath A."' showing total 23 results
Start Over Author "Jaleel, Mambarambath A."
23 results on '"Jaleel, Mambarambath A."'

7. Impact of Size for Gestational Age on Multivariate Analysis of Factors Associated with Necrotizing Enterocolitis in Preterm Infants: Retrospective Cohort Study.

Author

Sánchez-Rosado, Mariela, Reis, Jordan D., Jaleel, Mambarambath A., Clipp, Kimberly, Mangona, Kate L.M., Brown, L Steven, Nelson, David B., Wyckoff, Myra H., Verma, Diksha, Kiefaber, Isabelle, Lair, Cheryl S., Nayak, Sujir P., Burchfield, Patti J., Thomas, Anita, and Brion, Luc P.

Subjects
FETAL growth retardation -- Risk factors, RISK assessment, URINARY tract infections, STEROIDS, SMALL for gestational age, PRENATAL exposure delayed effects, DATA analysis, MULTIPLE regression analysis, FISHER exact test, LOGISTIC regression analysis, NEONATAL intensive care units, SEVERITY of illness index, RETROSPECTIVE studies, DESCRIPTIVE statistics, MULTIVARIATE analysis, CHI-squared test, MANN Whitney U Test, NEONATAL intensive care, NEONATAL necrotizing enterocolitis, LONGITUDINAL method, SEPSIS, ANALYSIS of variance, STATISTICS, DATA analysis software, DISEASE risk factors
Abstract

Objective Necrotizing enterocolitis (NEC) primarily affects preterm, especially small for gestational age (SGA), infants. This study was designed to (1) describe frequency and timing of NEC in SGA versus non-SGA infants and (2) assess whether NEC is independently associated with the severity of intrauterine growth failure. Study Design Retrospective cohort study of infants without severe congenital malformations born <33 weeks' gestational age (GA) carried out from 2009 to 2021. The frequency and time of NEC were compared between SGA and non-SGA infants. Multivariate logistic regression was used to assess whether NEC was independently associated with intrauterine growth restriction. Severe growth restriction was defined as birth weight Z -score < −2. Results Among 2,940 infants, the frequency of NEC was higher in SGA than in non-SGA infants (25/268 [9.3%] vs. 110/2,672 [4.1%], respectively, p < 0.001). NEC developed 2 weeks later in SGA than non-SGA infants. In multivariate analysis, the adjusted odds of NEC increased with extreme prematurity (<28 weeks' GA) and with severe but not moderate growth restriction. The adjusted odds of NEC increased with urinary tract infection or sepsis within a week prior to NEC, were lower in infants fed their mother's own milk until discharge, and did not change over five epochs. NEC was independently associated with antenatal steroid (ANS) exposure in infants with birth weight (BW) Z -score < 0. Conclusion NEC was more frequent in SGA than in non-SGA infants and developed 2 weeks later in SGA infants. NEC was independently associated with severe intrauterine growth failure and with ANS exposure in infants with BW Z -score < 0. Key Points We studied 2,940 infants <33 weeks' GA. We assessed NEC. NEC was more frequent in SGA infants. NEC occurred 2 weeks later in SGA infants. NEC was associated with severe growth restriction. [ABSTRACT FROM AUTHOR]

Published
2024
Full Text
View/download PDF

8. Impact of Size for Gestational Age on Multivariate Analysis of Factors Associated with Necrotizing Enterocolitis in Preterm Infants: Retrospective Cohort Study

Author

Sanchez-Rosado, Mariela, additional, Reis, Jordan D, additional, Jaleel, Mambarambath A, additional, Clipp, Kimberly, additional, Mangona, Kate Louise, additional, Brown, L Steven, additional, Nelson, David Bryan, additional, Wyckoff, Myra Helen, additional, Verma, Diksha, additional, Kiefaber, Isabelle, additional, Lair, Cheryl S, additional, Nayak, Sujir Pritha, additional, Burchfield, Patti J, additional, Thomas, Anita, additional, and Brion, Luc, additional

Published
2023
Full Text
View/download PDF

12. Association of antenatal steroids with neonatal mortality and morbidity in preterm infants born to mothers with diabetes mellitus and hypertension

Author

Weydig, Heather M., Rosenfeld, Charles R., Jaleel, Mambarambath A., Burchfield, Patti J., Frost, Mackenzie S., and Brion, Luc P.

Abstract

Background: Randomized trials of antenatal steroids (ANS) included women at 24–33 weeks gestational age (GA); however, few women had preeclampsia and women with diabetes mellitus (DM) were excluded. Methods: Cohort study including preterm births at 230/7–286/7weeks GA before (Epoch-1) and after (Epoch-2) expansion of ANS administration to women with DM and hypertensive disorders (HTN). We compared Group-A (neither DM nor HTN) and Group-B (DM and/or HTN). Results: Among 747 neonates the adjusted odds ratio (aOR) for surfactant administration, in-hospital mortality, severe intraventricular hemorrhage (IVH) and death or severe IVH were lower in ANS-exposed neonates than unexposed neonates. In Group-B, ANS administration was independently associated with less severe IVH and less death or severe IVH, but not less surfactant use or mortality. Conclusions: Increased ANS administration in women with DM and/or HTN was independently associated with less severe IVH and less death or severe IVH but without decrease in surfactant administration.

Published
2024
Full Text
View/download PDF

14. Decreasing Continuous Positive Airway Pressure Failure in Preterm Infants

Author

Kakkilaya, Venkatakrishna B., primary, Weydig, Heather M., additional, Smithhart, William E., additional, Renfro, Shelly D., additional, Garcia, Kristi M., additional, Brown, Cari M., additional, He, Henry, additional, Wagner, Sheron A., additional, Metoyer, Glenn C., additional, Brown, L. Steven, additional, Kapadia, Vishal S., additional, Savani, Rashmin C., additional, and Jaleel, Mambarambath A., additional

Published
2021
Full Text
View/download PDF

22. Change in Care Among Nonenrolled Patients During and After a Randomized Trial

Author

LeVan, Jaclyn M., primary, Wyckoff, Myra H., additional, Ahn, Chul, additional, Heyne, Roy, additional, Sánchez, Pablo J., additional, Chalak, Lina, additional, Jaleel, Mambarambath A., additional, Burchfield, P. Jeannette, additional, Christie, Lucy, additional, Soll, Roger, additional, Badger, Gary J., additional, and Brion, Luc P., additional

Published
2013
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results