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Copyright of Summa, Animali da Compagnia is the property of Point Veterinaire Italie s.r.l. and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Roche), ×100 objective gl DISCUSSION Intestinal osteosarcoma is an extremely rare neoplasm of domestic animals, with three cases currently reported in cats.1,2 Histologically, the diagnosis of osteosarcoma is supported by the presence of malignant mesenchymal cells associated with the production of osteoid and/or tumorous bone tissue. The histopathologic morphology of osteosarcoma can vary because of the pleomorphism of malignant osteoblasts (spindle-shaped, ovoid, or rounded cells) and the variable amount and appearance of osteoid.3 Cytologic preparations from osteosarcomas are usually moderately to highly cellular. Lymph node cytology revealed marked lymphoid hyperplasia with a neoplastic cell infiltration with the same neoplastic cells seen in the intestinal masses. [Extracted from the article]

Copyright of Summa, Animali da Compagnia is the property of Point Veterinaire Italie s.r.l. and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Summa, Animali da Compagnia is the property of Point Veterinaire Italie s.r.l. and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Summa, Animali da Compagnia is the property of Point Veterinaire Italie s.r.l. and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Summa, Animali da Compagnia is the property of Point Veterinaire Italie s.r.l. and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Objectives The aim of this study was to evaluate changes in circulating insulin-like growth factor type 1 (IGF-1) concentrations in hyperthyroid cats, before and after thiamazole treatment. Methods Thirty-four hyperthyroid cats were retrospectively included. Plasma free thyroxine (fT4) and IGF-1 concentrations were measured at diagnosis and 3 months after initiating antithyroid drug therapy. Results Median fT4 significantly decreased (P <0.001) after treatment (from 78 pmol/l [range 43–122 pmol/l] to 31 pmol/l [range below assay limit of detection to 88 pmol/l]), whereas IGF-1 values significantly increased (P <0.001) after treatment (from 117 ng/ml [33–341 ng/ml] to 221 ng/ml [36–865 ng/ml]). fT4 and IGF-1 concentrations were significantly negatively correlated both at diagnosis (r = −0.43, P = 0.01) and after treatment (r = −0.51, P = 0.002). Conclusions and relevance In cats, IGF-1 concentrations appear to be inversely proportional to the severity of hyperthyroidism and significantly increase after treatment with thiamazole. [ABSTRACT FROM AUTHOR]