Search

Artificial Intelligence (AI) and Large Language Models (LLMs) hold significant promise in revolutionizing healthcare, especially in clinical applications. Simultaneously, Digital Twin technology, which models and simulates complex systems, has gained traction in enhancing patient care. However, despite the advances in experimental clinical settings, the potential of AI and digital twins to streamline clinical operations remains largely untapped. This paper introduces a novel digital twin framework specifically designed to enhance oncology clinical operations. We propose the integration of multiple specialized digital twins, such as the Medical Necessity Twin, Care Navigator Twin, and Clinical History Twin, to enhance workflow efficiency and personalize care for each patient based on their unique data. Furthermore, by synthesizing multiple data sources and aligning them with the National Comprehensive Cancer Network (NCCN) guidelines, we create a dynamic Cancer Care Path, a continuously evolving knowledge base that enables these digital twins to provide precise, tailored clinical recommendations., Comment: Pre Print

On-device LLMs have gained increasing attention for their ability to enhance privacy and provide a personalized user experience. To facilitate learning with private and scarce local data, federated learning has become a standard approach, though it introduces challenges related to system and data heterogeneity among end users. As a solution, we propose a novel $\textbf{Co}$llaborative learning approach with a $\textbf{Mi}$xture of $\textbf{G}$eneralists and $\textbf{S}$pecialists (CoMiGS), being the first to effectively address both. Our approach distinguishes generalists and specialists by aggregating certain experts across end users while keeping others localized to specialize in user-specific datasets. A key innovation of our method is the bi-level optimization formulation of the Mixture-of-Experts learning objective, where the router is updated using a separate validation set that represents the target distribution. CoMiGS effectively balances collaboration and personalization, as demonstrated by its superior performance in scenarios with high data heterogeneity across multiple datasets. By design, our approach accommodates users' varying computational resources through different numbers of specialists. By decoupling resource abundance from data quantity, CoMiGS remains robust against overfitting-due to the generalists' regularizing effect-while adapting to local data through specialist expertise.

Collaborative learning is an important tool to train multiple clients more effectively by enabling communication among clients. Identifying helpful clients, however, presents challenging and often introduces significant overhead. In this paper, we model client-selection and model-training as two interconnected optimization problems, proposing a novel bilevel optimization problem for collaborative learning. We introduce CoBo, a scalable and elastic, SGD-type alternating optimization algorithm that efficiently addresses these problem with theoretical convergence guarantees. Empirically, CoBo achieves superior performance, surpassing popular personalization algorithms by 9.3% in accuracy on a task with high heterogeneity, involving datasets distributed among 80 clients.

Learning new tasks by drawing on prior experience gathered from other (related) tasks is a core property of any intelligent system. Gradient-based meta-learning, especially MAML and its variants, has emerged as a viable solution to accomplish this goal. One problem MAML encounters is its computational and memory burdens needed to compute the meta-gradients. We propose a new first-order variant of MAML that we prove converges to a stationary point of the MAML objective, unlike other first-order variants. We also show that the MAML objective does not satisfy the smoothness assumption assumed in previous works; we show instead that its smoothness constant grows with the norm of the meta-gradient, which theoretically suggests the use of normalized or clipped-gradient methods compared to the plain gradient method used in previous works. We validate our theory on a synthetic experiment.

AI assistants are being increasingly used by students enrolled in higher education institutions. While these tools provide opportunities for improved teaching and education, they also pose significant challenges for assessment and learning outcomes. We conceptualize these challenges through the lens of vulnerability, the potential for university assessments and learning outcomes to be impacted by student use of generative AI. We investigate the potential scale of this vulnerability by measuring the degree to which AI assistants can complete assessment questions in standard university-level STEM courses. Specifically, we compile a novel dataset of textual assessment questions from 50 courses at EPFL and evaluate whether two AI assistants, GPT-3.5 and GPT-4 can adequately answer these questions. We use eight prompting strategies to produce responses and find that GPT-4 answers an average of 65.8% of questions correctly, and can even produce the correct answer across at least one prompting strategy for 85.1% of questions. When grouping courses in our dataset by degree program, these systems already pass non-project assessments of large numbers of core courses in various degree programs, posing risks to higher education accreditation that will be amplified as these models improve. Our results call for revising program-level assessment design in higher education in light of advances in generative AI., Comment: 20 pages, 8 figures

The increasing size of deep neural networks necessitates effective model compression to improve computational efficiency and reduce their memory footprint. Sparsity and quantization are two prominent compression methods that have individually demonstrated significant reduction in computational and memory footprints while preserving model accuracy. While effective, the interplay between these two methods remains an open question. In this paper, we investigate the interaction between these two methods and assess whether their combination impacts final model accuracy. We mathematically prove that applying sparsity before quantization is the optimal sequence for these operations, minimizing error in computation. Our empirical studies across a wide range of models, including OPT and Llama model families (125M-8B) and ViT corroborate these theoretical findings. In addition, through rigorous analysis, we demonstrate that sparsity and quantization are not orthogonal; their interaction can significantly harm model accuracy, with quantization error playing a dominant role in this degradation. Our findings extend to the efficient deployment of large models in resource-limited compute platforms and reduce serving cost, offering insights into best practices for applying these compression methods to maximize efficacy without compromising accuracy.

Recent research on the grokking phenomenon has illuminated the intricacies of neural networks' training dynamics and their generalization behaviors. Grokking refers to a sharp rise of the network's generalization accuracy on the test set, which occurs long after an extended overfitting phase, during which the network perfectly fits the training set. While the existing research primarily focus on shallow networks such as 2-layer MLP and 1-layer Transformer, we explore grokking on deep networks (e.g. 12-layer MLP). We empirically replicate the phenomenon and find that deep neural networks can be more susceptible to grokking than its shallower counterparts. Meanwhile, we observe an intriguing multi-stage generalization phenomenon when increase the depth of the MLP model where the test accuracy exhibits a secondary surge, which is scarcely seen on shallow models. We further uncover compelling correspondences between the decreasing of feature ranks and the phase transition from overfitting to the generalization stage during grokking. Additionally, we find that the multi-stage generalization phenomenon often aligns with a double-descent pattern in feature ranks. These observations suggest that internal feature rank could serve as a more promising indicator of the model's generalization behavior compared to the weight-norm. We believe our work is the first one to dive into grokking in deep neural networks, and investigate the relationship of feature rank and generalization performance.

Scale has become a main ingredient in obtaining strong machine learning models. As a result, understanding a model's scaling properties is key to effectively designing both the right training setup as well as future generations of architectures. In this work, we argue that scale and training research has been needlessly complex due to reliance on the cosine schedule, which prevents training across different lengths for the same model size. We investigate the training behavior of a direct alternative - constant learning rate and cooldowns - and find that it scales predictably and reliably similar to cosine. Additionally, we show that stochastic weight averaging yields improved performance along the training trajectory, without additional training costs, across different scales. Importantly, with these findings we demonstrate that scaling experiments can be performed with significantly reduced compute and GPU hours by utilizing fewer but reusable training runs. Our code is available at https://github.com/epfml/schedules-and-scaling.

Decentralized learning is appealing as it enables the scalable usage of large amounts of distributed data and resources (without resorting to any central entity), while promoting privacy since every user minimizes the direct exposure of their data. Yet, without additional precautions, curious users can still leverage models obtained from their peers to violate privacy. In this paper, we propose Decor, a variant of decentralized SGD with differential privacy (DP) guarantees. Essentially, in Decor, users securely exchange randomness seeds in one communication round to generate pairwise-canceling correlated Gaussian noises, which are injected to protect local models at every communication round. We theoretically and empirically show that, for arbitrary connected graphs, Decor matches the central DP optimal privacy-utility trade-off. We do so under SecLDP, our new relaxation of local DP, which protects all user communications against an external eavesdropper and curious users, assuming that every pair of connected users shares a secret, i.e., an information hidden to all others. The main theoretical challenge is to control the accumulation of non-canceling correlated noise due to network sparsity. We also propose a companion SecLDP privacy accountant for public use., Comment: Accepted as conference paper at ICML 2024

We explore on-device self-supervised collaborative fine-tuning of large language models with limited local data availability. Taking inspiration from the collaborative learning community, we introduce three distinct trust-weighted gradient aggregation schemes: weight similarity-based, prediction similarity-based and validation performance-based. To minimize communication overhead, we integrate Low-Rank Adaptation (LoRA) and only exchange LoRA weight updates. Our protocols, driven by prediction and performance metrics, surpass both FedAvg and local fine-tuning methods, which is particularly evident in realistic scenarios with more diverse local data distributions. The results underscore the effectiveness of our approach in addressing heterogeneity and scarcity within local datasets.

We introduce QuaRot, a new Quantization scheme based on Rotations, which is able to quantize LLMs end-to-end, including all weights, activations, and KV cache in 4 bits. QuaRot rotates LLMs in a way that removes outliers from the hidden state without changing the output, making quantization easier. This computational invariance is applied to the hidden state (residual) of the LLM, as well as to the activations of the feed-forward components, aspects of the attention mechanism and to the KV cache. The result is a quantized model where all matrix multiplications are performed in 4-bits, without any channels identified for retention in higher precision. Our quantized LLaMa2-70B model has losses of at most 0.29 WikiText-2 perplexity and retains 99% of the zero-shot performance. Code is available at: https://github.com/spcl/QuaRot., Comment: 19 pages, 6 figures

In this study, we systematically evaluate the impact of common design choices in Mixture of Experts (MoEs) on validation performance, uncovering distinct influences at token and sequence levels. We also present empirical evidence showing comparable performance between a learned router and a frozen, randomly initialized router, suggesting that learned routing may not be essential. Our study further reveals that Sequence-level routing can result in topic-specific weak expert specialization, in contrast to syntax specialization observed with Token-level routing.

The performance of optimization methods is often tied to the spectrum of the objective Hessian. Yet, conventional assumptions, such as smoothness, do often not enable us to make finely-grained convergence statements -- particularly not for non-convex problems. Striving for a more intricate characterization of complexity, we introduce a unique concept termed graded non-convexity. This allows to partition the class of non-convex problems into a nested chain of subclasses. Interestingly, many traditional non-convex objectives, including partially convex problems, matrix factorizations, and neural networks, fall within these subclasses. As a second contribution, we propose gradient methods with spectral preconditioning, which employ inexact top eigenvectors of the Hessian to address the ill-conditioning of the problem, contingent on the grade. Our analysis reveals that these new methods provide provably superior convergence rates compared to basic gradient descent on applicable problem classes, particularly when large gaps exist between the top eigenvalues of the Hessian. Our theory is validated by numerical experiments executed on multiple practical machine learning problems.

In recent years, attention-based transformers have achieved tremendous success across a variety of disciplines including natural languages. A key ingredient behind their success is the generative pretraining procedure, during which these models are trained on a large text corpus in an auto-regressive manner. To shed light on this phenomenon, we propose a new framework that allows both theory and systematic experiments to study the sequential modeling capabilities of transformers through the lens of Markov chains. Inspired by the Markovianity of natural languages, we model the data as a Markovian source and utilize this framework to systematically study the interplay between the data-distributional properties, the transformer architecture, the learnt distribution, and the final model performance. In particular, we theoretically characterize the loss landscape of single-layer transformers and show the existence of global minima and bad local minima contingent upon the specific data characteristics and the transformer architecture. Backed by experiments, we demonstrate that our theoretical findings are in congruence with the empirical results. We further investigate these findings in the broader context of higher order Markov chains and deeper architectures, and outline open problems in this arena. Code is available at \url{https://github.com/Bond1995/Markov}.

Interpretability for neural networks is a trade-off between three key requirements: 1) faithfulness of the explanation (i.e., how perfectly it explains the prediction), 2) understandability of the explanation by humans, and 3) model performance. Most existing methods compromise one or more of these requirements; e.g., post-hoc approaches provide limited faithfulness, automatically identified feature masks compromise understandability, and intrinsically interpretable methods such as decision trees limit model performance. These shortcomings are unacceptable for sensitive applications such as education and healthcare, which require trustworthy explanations, actionable interpretations, and accurate predictions. In this work, we present InterpretCC (interpretable conditional computation), a family of interpretable-by-design neural networks that guarantee human-centric interpretability, while maintaining comparable performance to state-of-the-art models by adaptively and sparsely activating features before prediction. We extend this idea into an interpretable, global mixture-of-experts (MoE) model that allows humans to specify topics of interest, discretely separates the feature space for each data point into topical subnetworks, and adaptively and sparsely activates these topical subnetworks for prediction. We apply variations of the InterpretCC architecture for text, time series and tabular data across several real-world benchmarks, demonstrating comparable performance with non-interpretable baselines, outperforming interpretable-by-design baselines, and showing higher actionability and usefulness according to a user study.

The transformer architecture by Vaswani et al. (2017) is now ubiquitous across application domains, from natural language processing to speech processing and image understanding. We propose DenseFormer, a simple modification to the standard architecture that improves the perplexity of the model without increasing its size -- adding a few thousand parameters for large-scale models in the 100B parameters range. Our approach relies on an additional averaging step after each transformer block, which computes a weighted average of current and past representations -- we refer to this operation as Depth-Weighted-Average (DWA). The learned DWA weights exhibit coherent patterns of information flow, revealing the strong and structured reuse of activations from distant layers. Experiments demonstrate that DenseFormer is more data efficient, reaching the same perplexity of much deeper transformer models, and that for the same perplexity, these new models outperform transformer baselines in terms of memory efficiency and inference time.

Controlled abstractive summarization focuses on producing condensed versions of a source article to cover specific aspects by shifting the distribution of generated text towards a desired style, e.g., a set of topics. Subsequently, the resulting summaries may be tailored to user-defined requirements. This paper presents a new Transformer-based architecture capable of producing topic-focused summaries. The architecture modifies the cross-attention mechanism of the Transformer to bring topic-focus control to the generation process while not adding any further parameters to the model. We show that our model sets a new state of the art on the NEWTS dataset in terms of topic-focused abstractive summarization as well as a topic-prevalence score. Moreover, we show via extensive experiments that our proposed topical cross-attention mechanism can be plugged into various Transformer models, such as BART and T5, improving their performance on the CNN/Dailymail and XSum benchmark datasets for abstractive summarization. This is achieved via fine-tuning, without requiring training from scratch. Finally, we show through human evaluation that our model generates more faithful summaries outperforming the state-of-the-art Frost model.

The coverage and composition of the pretraining data significantly impacts the generalization ability of Large Language Models (LLMs). Despite its importance, recent LLMs still rely on heuristics and trial and error to increase or reduce the influence of data-domains. We propose DOmain reweighting with Generalization Estimation (DoGE), which optimizes the probability of sampling from each domain (domain weights) in a principled way. Our approach is a two-stage process consisting of (i) training a proxy model to obtain domain weights using a bi-level optimization algorithm; (ii) training a larger base model by sampling training domains according to the learned domain weights. In our experiments, we extensively show how DoGE improves the generalization of the base model to any target data mixture. On the SlimPajama dataset, our base model gets better perplexity and few-shot reasoning accuracies across $6$ tasks compared to baseline methods. Moreover, aiming to generalize to out-of-domain target tasks, which is unseen in the pretraining corpus (OOD domain), DoGE can effectively identify inter-domain dependencies, and consistently achieves better test perplexity on the target domain.

Automatic data selection and curriculum design for training large language models is challenging, with only a few existing methods showing improvements over standard training. Furthermore, current schemes focus on domain-level selection, overlooking the more fine-grained contributions of each individual training point. It is difficult to apply traditional datapoint selection methods on large language models: most online batch selection methods perform two-times forward or backward passes, which introduces considerable extra costs with large-scale models. To mitigate these obstacles, we propose irreducible curriculum as a curriculum learning algorithm for language model pretraining, which prioritizes samples with higher learnability. Specifically, to avoid prohibitive extra computation overhead, we simulate the sample loss along the main model's training trajectory using a small-scale proxy model. Our experiments on the RedPajama-1B dataset demonstrate a consistent improvement on validation perplexity across all 7 domains compared to random uniform baseline and the anti-curriculum strategy. Our method also reduces the sharpness of the network and illustrates a better 5-shot accuracy on MMLU benchmarks.

Data-parallel SGD is the de facto algorithm for distributed optimization, especially for large scale machine learning. Despite its merits, communication bottleneck is one of its persistent issues. Most compression schemes to alleviate this either assume noiseless communication links, or fail to achieve good performance on practical tasks. In this paper, we close this gap and introduce LASER: LineAr CompreSsion in WirEless DistRibuted Optimization. LASER capitalizes on the inherent low-rank structure of gradients and transmits them efficiently over the noisy channels. Whilst enjoying theoretical guarantees similar to those of the classical SGD, LASER shows consistent gains over baselines on a variety of practical benchmarks. In particular, it outperforms the state-of-the-art compression schemes on challenging computer vision and GPT language modeling tasks. On the latter, we obtain $50$-$64 \%$ improvement in perplexity over our baselines for noisy channels.

Scaling language models to larger and deeper sizes has led to significant boosts in performance. Even though the size of these models limits their application in compute-constrained environments, the race to continually develop ever larger and deeper foundational models is underway. At the same time -- regardless of the model size -- task-specific techniques continue to play a pivotal role in achieving optimal downstream performance. One of these techniques, called Chain-of-Thought (CoT), is particularly interesting since, as we point out in this work, it resembles employing a deeper transformer through re-applying the model multiple times. However, a key subtlety in computing the attention of past tokens differentiates CoT from simply applying the model several times. Based on this insight, we propose CoTFormer, a novel architecture which closely mimics CoT at the token level, allowing us to obtain significantly improved accuracies close to much larger models. While applying CoT introduces additional computation costs, we compensate for it by leveraging CoTFormer's special compatibility with token-wise variable depth. Through a compute adaptive model -- which automatically allocates the compute to tokens that need it most -- we show that it is possible to reduce the computation cost significantly without any reduction in accuracy, and with further compute cost reductions possible while maintaining a competitive accuracy.

Predicting multiple real-world tasks in a single model often requires a particularly diverse feature space. Multimodal (MM) models aim to extract the synergistic predictive potential of multiple data types to create a shared feature space with aligned semantic meaning across inputs of drastically varying sizes (i.e. images, text, sound). Most current MM architectures fuse these representations in parallel, which not only limits their interpretability but also creates a dependency on modality availability. We present MultiModN, a multimodal, modular network that fuses latent representations in a sequence of any number, combination, or type of modality while providing granular real-time predictive feedback on any number or combination of predictive tasks. MultiModN's composable pipeline is interpretable-by-design, as well as innately multi-task and robust to the fundamental issue of biased missingness. We perform four experiments on several benchmark MM datasets across 10 real-world tasks (predicting medical diagnoses, academic performance, and weather), and show that MultiModN's sequential MM fusion does not compromise performance compared with a baseline of parallel fusion. By simulating the challenging bias of missing not-at-random (MNAR), this work shows that, contrary to MultiModN, parallel fusion baselines erroneously learn MNAR and suffer catastrophic failure when faced with different patterns of MNAR at inference. To the best of our knowledge, this is the first inherently MNAR-resistant approach to MM modeling. In conclusion, MultiModN provides granular insights, robustness, and flexibility without compromising performance., Comment: Accepted as a full paper at NeurIPS 2023 in New Orleans, USA