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Introduction: Disease uncertainty refers to the inability to assign meaning to events related to the illness. Uncertainty of the disease can affect various aspects of human life such as psychological aspects. Objectives: This study aims to examine the relationship between disease uncertainty and perceived stress in COVID-19 patients. Methods: An analytical cross-sectional study was conducted on 212 hospitalized COVID-19 patients who were initially admitted to the intensive care units (ICUs) and later transferred to general wards within the same hospitals. Three instruments were utilized to collect data for this study. The Demographic Information Questionnaire, Mishel Uncertainty in Illness Scale (MUIS) for disease uncertainty, and Perceived Stress Questionnaire. For data analysis, both descriptive and inferential statistics were employed using IBM SPSS Statistics version 25. Results: The Pearson correlation coefficient matrix results showed a positive and significant relationship between uncertainty about the illness (P <.001, r = 0.829), ambiguity (P <.001, r = 0.795), complexity (P <.001, r = 0.835), inconsistency or instability (P <.001, r = 0.787), and unpredictability (P <.001, r = 0.776) with perceived stress in COVID-19 patients transferred from the intensive care units. Conclusion: Based on the findings of the current study, both uncertainty and perceived stress are elevated among COVID-19 patients, and a significant and direct relationship exists between these two variables. Healthcare providers, particularly nurses, should address the uncertainties surrounding emerging diseases, both at the hospital and community levels. [ABSTRACT FROM AUTHOR]

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Purpose: End-Stage Renal Disease (ESRD) is a severe form of chronic kidney disease (CKD). Hemodialysis has increased the life expectancy in patients with renal failure. The most common complication of vascular access is thrombosis in lines. Medical interventions such as anti-thrombolytic drugs can be more effective and affordable. In this study, we aimed to evaluate streptokinase efficacy on the success rate and secondary patency rate of thrombosed hemodialysis catheters. Methods: In this prosepective study, 34 dialysis patients with thrombosed permicaths who entered to Razi hospital, were examined. The study population included the hospital during one year and three months. The cases received streptokinase, three times according to protocol. Each of the successful cases had been controlled after three months. After collection, the data were analyzed by SPSS version 21. Results: The frequency of males and females was too close. Findings showed that the Streptokinase was effective in 80 % of patients. And this effect continued for 22.1±18.2 months on average, and more than 70 % of patients' permcaths can be used after 3 months. More than 90% of patients didn't report any allergic reactions, and the allergic reactions have been limited to fever, nausea and back pain. Conclusion: The study showed although the replacement of occluded dialysis catheters is expensive and invasive, using streptokinase is effective and affordable, and is more secure than invasive methods. [ABSTRACT FROM AUTHOR]

Primary simultaneous multiple organs teratomas are extremely rare. They usually arise in the gonads, and only 1–3 % of them arise in the mediastinum. We present a case of simultaneous multiple organs immature teratomas who was admitted to Razi hospital because of cough, dyspnea, and left-side supraclavicular mass. Computed tomography (CT) showed a big mass with multiple high densities, nodular, semi-solid, heterogenic structures on the left side of the neck, left-side anterior mediastinum, right-side middle mediastinum and right-side suprarenal region. CT-guided needle biopsy was performed and histopathological study showed immature teratoma. After performing neoadjuvant therapy, the tumors were removed. The patient underwent chemo radiation therapy on the mediastinum and abdomen. On 6-months follow-up, he was asymptomatic. This case is being reported because of the rarity of multiple organs immature teratomas and informing other clinicians about managing these cases. [ABSTRACT FROM AUTHOR]