1. Staphylococcus argenteus bacteremia in the Republic of Korea
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Minkyeong Lee, Yunsang Choi, Seong Jin Choi, Song Mi Moon, Eu Suk Kim, Hong Bin Kim, Soyeon Ahn, Hyunju Lee, Jaeeun Kim, Dong Woo Shin, Jinki Yeom, Jeong Su Park, and Kyoung-Ho Song
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Staphylococcus aureus ,Staphylococcus argenteus ,bacteremia ,MALDI-TOF MS ,Republic of Korea ,Microbiology ,QR1-502 - Abstract
ABSTRACTIn 2015, Staphylococcus argenteus and Staphylococcus schweitzeri were proposed as new species, distinct from Staphylococcus aureus and collectively referred to as the S. aureus complex. However, no clinical reports of these new species exist in Korea. Upon the application of matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS) for all bloodstream isolates since September 2022, S. argenteus was identified in one patient. Therefore, we aimed to search for new species among the archives of the S. aureus bacteremia cohort and describe their clinical and microbiological characteristics. Among the 691 archived S. aureus isolates between 2012 and 2018, one was identified as S. argenteus via MALDI-TOF MS. Both S. argenteus isolates (one in 2022) were obtained from patients with extensive pneumonia accompanied by bacteremia and both cases had fatal outcomes. They harbored multiple virulence genes (clfA, clfB, fnbpA, sdrC, sdrD, sdrE, bbp, cna, see, seg, sei, blaZ, fnbpB, and map) but did not harbor mecA and pvl. No matched sequence type (ST) was found in either isolate, and both S. argenteus isolates were closely related to ST1594, ST1593, ST1793, and ST1303, which belonged to S. argenteus. S. argenteus accounted for
- Published
- 2024
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