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2. Associations of exposure to outdoor PM2.5 and NO2 during pregnancy with childhood asthma, rhinitis, and eczema in a predominantly rural French mother-child cohort

Author

Patlán-Hernández, Alan R., Savouré, Marine, Audureau, Etienne, Monfort, Christine, de Castro, Montserrat, Epaud, Ralph, de Hoogh, Kees, Hough, Ian, Kloog, Itai, Lanone, Sophie, Lepeule, Johanna, Nieuwenhuijsen, Mark, Vienneau, Danielle, Warembourg, Charline, Chevrier, Cécile, and Jacquemin, Bénédicte

Published
2024
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3. Impact of long-term exposure to ambient ozone on lung function over a course of 20 years (The ECRHS study): a prospective cohort study in adults

Author

Zhao, Tianyu, Markevych, Iana, Fuertes, Elaine, de Hoogh, Kees, Accordini, Simone, Boudier, Anne, Casas, Lidia, Forsberg, Bertil, Garcia Aymerich, Judith, Gnesi, Marco, Holm, Mathias, Janson, Christer, Jarvis, Deborah, Johannessen, Ane, Jörres, Rudolf A., Karrasch, Stefan, Leynaert, Benedicte, Maldonado Perez, José Antonio, Malinovschi, Andrei, Martínez-Moratalla, Jesús, Modig, Lars, Nowak, Dennis, Potts, James, Probst-Hensch, Nicole, Sánchez-Ramos, José Luis, Siroux, Valerie, Urrutia Landa, Isabel, Vienneau, Danielle, Villani, Simona, Jacquemin, Bénédicte, and Heinrich, Joachim

Published
2023
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4. Residential greenspace and lung function decline over 20 years in a prospective cohort: The ECRHS study

Author

Markevych, Iana, Zhao, Tianyu, Fuertes, Elaine, Marcon, Alessandro, Dadvand, Payam, Vienneau, Danielle, Garcia Aymerich, Judith, Nowak, Dennis, de Hoogh, Kees, Jarvis, Deborah, Abramson, Michael J., Accordini, Simone, Amaral, Andre FS, Bentouhami, Hayat, Jacobsen Bertelsen, Randi, Boudier, Anne, Bono, Roberto, Bowatte, Gayan, Casas, Lidia, Dharmage, Shyamali C, Forsberg, Bertil, Gislason, Thorarinn, Gnesi, Marco, Holm, Mathias, Jacquemin, Benedicte, Janson, Christer, Jogi, Rain, Johannessen, Ane, Keidel, Dirk, Leynaert, Benedicte, Maldonado Perez, José Antonio, Marchetti, Pierpaolo, Migliore, Enrica, Martínez-Moratalla, Jesús, Orru, Hans, Pin, Isabelle, Potts, James, Probst-Hensch, Nicole, Ranzi, Andrea, Sánchez-Ramos, José Luis, Siroux, Valerie, Soussan, David, Sunyer, Jordi, Urrutia Landa, Isabel, Villani, Simona, and Heinrich, Joachim

Published
2023
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7. Contributors

Author

Anto, Aram, primary, Anto, Josep M, additional, Balli, Fabio, additional, Bedard, Annabelle, additional, Bedbrook, Anna, additional, Bousquet, Jean, additional, Brussino, Luisa, additional, Burgel, Pierre-Régis, additional, Burte, Emilie, additional, Camargo, Jr., Carlos A., additional, Canonica, G Walter, additional, Carr, Tara F., additional, Casale, Thomas, additional, Casas, Lidia, additional, Chassagnon, Guillaume, additional, Czarlewski, Wienczyslawa, additional, Dharmage, Shyamali C., additional, Dumas, Orianne, additional, Fonseca, Joao A, additional, Gaga, Mina, additional, Gemicioglu, Bilun, additional, Günther, Sven, additional, Habib, Stéfanie, additional, Hasegawa, Kohei, additional, Heinrich, Joachim, additional, Idrose, N. Sabrina, additional, Jacquemin, Bénédicte, additional, Klimek, Ludger, additional, Kvedariene, Violeta, additional, Leynaert, Bénédicte, additional, Li, Zhen, additional, Louis, Renaud, additional, Martin, Clémence, additional, Morin, Andréanne, additional, Moual, Nicole Le, additional, Nadif, Rachel, additional, Nagase, Hiroyuki, additional, Ober, Carole, additional, Pastré, Jean, additional, Patel, Sanjay B., additional, Puggioni, Francesca, additional, Real, Francisco Gómez, additional, Roche, Nicolas, additional, Sastre, Joaquin, additional, Savouré, Marine, additional, Schoettler, Nathan, additional, Scichilone, Nicola, additional, Sousa-Pinto, Bernardo, additional, Suzukawa, Maho, additional, Toivonen, Laura, additional, Valiulis, Arunas, additional, Varraso, Raphaëlle, additional, Yorgancioglu, Arzu, additional, Zervas, Eleptherios, additional, and Zuberbier, Torsten, additional

Published
2023
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9. Influence of exposure assessment methods on associations between long-term exposure to outdoor fine particulate matter and risk of cancer in the French cohort Gazel

Author

Lequy, Emeline, Zare Sakhvidi, Mohammad Javad, Vienneau, Danielle, de Hoogh, Kees, Chen, Jie, Dupuy, Jean-François, Garès, Valérie, Burte, Emilie, Bouaziz, Olivier, Le Tertre, Alain, Wagner, Vérène, Hertel, Ole, Christensen, Jesper Heile, Zhivin, Sergey, Siemiatycki, Jack, Goldberg, Marcel, Zins, Marie, and Jacquemin, Bénédicte

Published
2022
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11. LongITools: Dynamic longitudinal exposome trajectories in cardiovascular and metabolic noncommunicable diseases

Author

Ronkainen, Justiina, Nedelec, Rozenn, Atehortua, Angelica, Balkhiyarova, Zhanna, Cascarano, Anna, Ngoc Dang, Vien, Elhakeem, Ahmed, van Enckevort, Esther, Goncalves Soares, Ana, Haakma, Sido, Halonen, Miia, Heil, Katharina F., Heiskala, Anni, Hyde, Eleanor, Jacquemin, Bénédicte, Keikkala, Elina, Kerckhoffs, Jules, Klåvus, Anton, Kopinska, Joanna A., Lepeule, Johanna, Marazzi, Francesca, Motoc, Irina, Näätänen, Mari, Ribbenstedt, Anton, Rundblad, Amanda, Savolainen, Otto, Simonetti, Valentina, de Toro Eadie, Nina, Tzala, Evangelia, Ulrich, Anna, Wright, Thomas, Zarei, Iman, d’Amico, Enrico, Belotti, Federico, Brunius, Carl, Castleton, Christopher, Charles, Marie-Aline, Gaillard, Romy, Hanhineva, Kati, Hoek, Gerard, Holven, Kirsten B., Jaddoe, Vincent W. V., Kaakinen, Marika A., Kajantie, Eero, Kavousi, Maryam, Lakka, Timo, Matthews, Jason, Piano Mortari, Andrea, Vääräsmäki, Marja, Voortman, Trudy, Webster, Claire, Zins, Marie, Atella, Vincenzo, Bulgheroni, Maria, Chadeau-Hyam, Marc, Conti, Gabriella, Evans, Jayne, Felix, Janine F., Heude, Barbara, Järvelin, Marjo-Riitta, Kolehmainen, Marjukka, Landberg, Rikard, Lekadir, Karim, Parusso, Stefano, Prokopenko, Inga, de Rooij, Susanne R., Roseboom, Tessa, Swertz, Morris, Timpson, Nicholas, Ulven, Stine M., Vermeulen, Roel, Juola, Teija, Sebert, Sylvain, Sebert, Sylvain, Juola, Teija, Nedelec, Rozenn, Ronkainen, Justiina, Heiskala, Anni, Halonen, Miia, He, Yiyan, Miettunen, Jouko, Karhunen, Ville, Kajantie, Eero, Vääräsmäki, Marja, Keikkala, Elina, Nyberg, Pia, Serpi, Raisa, Felix, Janine, Jaddoe, Vincent, Marques, Irene, Moreira da Silva Santos, Susana, Kavousi, Maryam, Voortman, Trudy, Ginos, Bigina, Chadeau-Hyam, Marc, Järvelin, Marjo-Riitta, Tzala, Evangelia, De Toro, Nina, Wright, Thomas, Bodinier, Barbara, Dagnino, Sonia, Evans, Jayne, Webster, Claire, Kolehmainen, Marjukka, Hanhineva, Kati, Lakka, Timo, Savolainen, Otto, Zarei, Iman, Näätänen, Mari, Klåvus, Anton, Eloranta, Aino-Maija, Väistö, Juuso, Kårlund, Anna, Mikkonen, Santtu, Atalay, Merja, Atalay, Mustafa, Landberg, Rikard, Brunius, Carl, Ribbenstedt, Anton, Swertz, Morris, Hyde, Eleanor, Haakma, Sido, van Enckevort, Esther, Heude, Barbara, Charles, Marie-Aline, Zins, Marie, Lepeule, Johanna, Jacquemin, Bénédicte, Calas, Lucinda, Lequy-Flahault, Emeline, Lun Yuan, Wen, Seyve, Emie, Conti, Gabriella, Vermeulen, Roel, Hoek, Gerard, Kerckhoffs, Jules, Prokopenko, Inga, Kaakinen, Marika, Balkhiyarova, Zhanna, Ulrich, Anna, Roseboom, Tessa, De Rooij, Susanne, Motoc, Irina, Marie Ulven, Stine, Holven, Kirsten B., Matthews, Jason, Rundblad, Amanda, Das, Siddhartha, Timpson, Nicholas, Elhakeem, Ahmed, Luiza Goncalves Soares, Ana, Lekadir, Karim, Maria Cascarano, Anna, Maria Atehortua Labrador, Angélica, Ngoc Dang, Vien, Heil, Katharina F., Gallin, Catherine, Díaz, Oliver, Bulgheroni, Maria, Simonetti, Valentina, D’Amico, Enrico, Giani, Laura, Manzino, Fabrizio, Parusso, Stefano, Castleton, Christopher, Moimas, Diego, Atella, Vincenzo, Piano Mortari, Andrea, Kopinska, Joanna, Marazzi, Francesca, Giaccherini, Matilde, and Belotti, Federico

Published
2022
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12. Long-term air pollution exposure is associated with increased severity of rhinitis in 2 European cohorts

Author

Burte, Emilie, Leynaert, Bénédicte, Marcon, Alessandro, Bousquet, Jean, Benmerad, Meriem, Bono, Roberto, Carsin, Anne-Elie, de Hoogh, Kees, Forsberg, Bertil, Gormand, Frederic, Heinrich, Joachim, Just, Jocelyne, Nieuwenhuijsen, Mark, Pin, Isabelle, Stempfelet, Morgane, Sunyer, Jordi, Villani, Simona, Künzli, Nino, Siroux, Valérie, Jarvis, Deborah, Nadif, Rachel, and Jacquemin, Bénédicte

Published
2020
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15. Long-term exposure to ambient ozone and lung function decline over 20 years in adults: The ECRHS study

Author

Zhao, Tianyu, primary, Markevych, Iana, additional, Fuertes, Elaine, additional, Hoogh, Kees De, additional, Accordini, Simone, additional, Boudier, Anne, additional, Casas, Lidia, additional, Forsberg, Bertil, additional, Aymerich, Judith Garcia, additional, Gnesi, Marco, additional, Holm, Mathias, additional, Janson, Christer, additional, Jarvis, Deborah, additional, Johannessen, Ane, additional, Leynaert, Benedicte, additional, Perez, José Antonio Maldonado, additional, Malinovschi, Andrei, additional, Modig, Lars, additional, Potts, James, additional, Hensch, Nicole Probst, additional, Siroux, Valerie, additional, Landa, Isabel Urrutia, additional, Vienneau, Danielle, additional, Villani, Simona, additional, and Jacquemin, Bénédicte, additional

Published
2023
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18. Association Between Short-term Exposure to Ultrafine Particles and Mortality in Eight European Urban Areas

Author

UF&HEALTH Study Group, Stafoggia, Massimo, Schneider, Alexandra, Cyrys, Josef, Samoli, Evangelia, Andersen, Zorana Jovanovic, Bedada, Getahun Bero, Bellander, Tom, Cattani, Giorgio, Eleftheriadis, Konstantinos, Faustini, Annunziata, Hoffmann, Barbara, Jacquemin, Bénédicte, Katsouyanni, Klea, Massling, Andreas, Pekkanen, Juha, Perez, Noemi, Peters, Annette, Quass, Ulrich, Yli-Tuomi, Tarja, and Forastiere, Francesco

Published
2017

19. Mechanisms of the Development of Allergy (MeDALL): Introducing novel concepts in allergy phenotypes

Author

Anto, Josep M., Bousquet, Jean, Akdis, Mubeccel, Auffray, Charles, Keil, Thomas, Momas, Isabelle, Postma, Dirkje S., Valenta, Rudolf, Wickman, Magnus, Cambon-Thomsen, Anne, Haahtela, Tari, Lambrecht, Bart N., Lodrup Carlsen, Karin C., Koppelman, Gerard H., Sunyer, Jordi, Zuberbier, Torsten, Annesi-Maesano, Isabelle, Arno, Albert, Bindslev-Jensen, Carsten, De Carlo, Giuseppe, Forastiere, Francesco, Heinrich, Joachim, Kowalski, Marek L., Maier, Dieter, Melén, Erik, Smit, Henriette A., Standl, Marie, Wright, John, Asarnoj, Anna, Benet, Marta, Ballardini, Natalia, Garcia-Aymerich, Judith, Gehring, Ulrike, Guerra, Stefano, Hohmann, Cynthia, Kull, Inger, Lupinek, Christian, Pinart, Mariona, Skrindo, Ingebjorg, Westman, Marit, Smagghe, Delphine, Akdis, Cezmi, Andersson, Niklas, Bachert, Claus, Ballereau, Stephane, Ballester, Ferran, Basagana, Xavier, Bedbrook, Anna, Bergstrom, Anna, von Berg, Andrea, Brunekreef, Bert, Burte, Emilie, Carlsen, Kai-Hakon, Chatzi, Leda, Coquet, Jonathan M., Curin, Mirela, Demoly, Pascal, Eller, Esben, Fantini, Maria Pia, von Hertzen, Leena, Hovland, Vergard, Jacquemin, Benedicte, Just, Jocelyne, Keller, Theresa, Kiss, Renata, Kogevinas, Manolis, Koletzko, Sibylle, Lau, Susanne, Lehmann, Irina, Lemonnier, Nicolas, Mäkelä, Mika, Mestres, Jordi, Mowinckel, Peter, Nadif, Rachel, Nawijn, Martijn C., Pellet, Johan, Pin, Isabelle, Porta, Daniela, Rancière, Fanny, Rial-Sebbag, Emmanuelle, Saeys, Yvan, Schuijs, Martijn J., Siroux, Valerie, Tischer, Christina G., Torrent, Mathies, Varraso, Raphaelle, Wenzel, Kalus, and Xu, Cheng-Jian

Published
2017
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21. Ambient Air Pollution Exposure and Cerebral White Matter Hyperintensities in Older Adults: A Cross-Sectional Analysis in the Three-City Montpellier Study.

Author

Duchesne, Jeanne, Carrière, Isabelle, Artero, Sylvaine, Brickman, Adam M., Maller, Jerome, Meslin, Chantal, Jie Chen, Vienneau, Danielle, de Hoogh, Kees, Jacquemin, Bénédicte, Berr, Claudine, and Mortamais, Marion

Subjects
NITROGEN oxide analysis, CEREBROVASCULAR disease diagnosis, CARBON analysis, AIR pollution, BIOMARKERS, PARTICULATE matter, CONFIDENCE intervals, CROSS-sectional method, MILD cognitive impairment, MAGNETIC resonance imaging, WHITE matter (Nerve tissue), RESEARCH funding, DESCRIPTIVE statistics, LOGISTIC regression analysis, ODDS ratio, OLD age
Abstract

BACKGROUND: Growing epidemiological evidence suggests an adverse relationship between exposure to air pollutants and cognitive health, and this could be related to the effect of air pollution on vascular health. OBJECTIVE: We aim to evaluate the association between air pollution exposure and a magnetic resonance imaging (MRI) marker of cerebral vascular burden, white matter hyperintensities (WMH). METHODS: This cross-sectional analysis used data from the French Three-City Montpellier study. Randomly selected participants 65–80 years of age underwent an MRI examination to estimate their total and regional cerebral WMH volumes. Exposure to fine particulate matter (PM2.5), nitrogen dioxide (NO2), and black carbon (BC) at the participants’ residential address during the 5 years before the MRI examination was estimated with land use regression models. Multinomial and binomial logistic regression assessed the associations between exposure to each of the three pollutants and categories of total and lobar WMH volumes. RESULTS: Participants’ (푛=582) median age at MRI was 70.7 years [interquartile range (IQR): 6.1], and 52% (푛=300) were women. Median exposure to air pollution over the 5 years before MRI acquisition was 24.3 (IQR: 1.7) μg/m³ for PM2.5, 48.9 (14.6) μg/m³ for NO2, and 2.66 (0.60) 10-5/m for BC. We found no significant association between exposure to the three air pollutants and total WMH volume. We found that PM2.5 exposure was significantly associated with higher risk of temporal lobe WMH burden [odds ratio (OR) for an IQR increase=1.82 (95% confidence interval: 1.41, 2.36) for the second volume tercile, 2.04 (1.59, 2.61) for the third volume tercile, reference: first volume tercile]. Associations for other regional WMH volumes were inconsistent. CONCLUSION: In this population-based study in older adults, PM2.5 exposure was associated with increased risk of high WMH volume in the temporal lobe, strengthening the evidence on PM2.5 adverse effect on the brain. Further studies looking at different markers of cerebrovascular damage are still needed to document the potential vascular effects of air pollution [ABSTRACT FROM AUTHOR]

Published
2023
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22. Association of urinary and ambient black carbon, and other ambient air pollutants with risk of prediabetes and metabolic syndrome in children and adolescents

Author

Nagrani, Rajini, primary, Marron, Manuela, additional, Bongaerts, Eva, additional, Nawrot, Tim S., additional, Ameloot, Marcel, additional, de Hoogh, Kees, additional, Vienneau, Danielle, additional, Lequy, Emeline, additional, Jacquemin, Bénédicte, additional, Guenther, Kathrin, additional, De Ruyter, Thaïs, additional, Mehlig, Kirsten, additional, Molnár, Dénes, additional, Moreno, Luis A., additional, Russo, Paola, additional, Veidebaum, Toomas, additional, Ahrens, Wolfgang, additional, and Buck, Christoph, additional

Published
2023
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24. Outdoor air pollution and asthma in a changing climate

Author

Jacquemin, Bénédicte, Burte, Emilie, Savouré, Marine, Heinrich, Joachim, EHESP-Irset (EHESP-Irset), École des Hautes Études en Santé Publique [EHESP] (EHESP), Université de Rennes (UR), Centre de recherche en épidémiologie et santé des populations (CESP), Université de Versailles Saint-Quentin-en-Yvelines (UVSQ)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Hôpital Paul Brousse-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Paris-Saclay, and Ludwig Maximilian University [Munich] (LMU)

Subjects
Particles, Epidemiology, [SDV]Life Sciences [q-bio], Allergies, Air pollution, Climate change, Pollen, Traffic, Gases, Asthma
Abstract

International audience; The purpose of the chapter is to summarize the recent research on the associations between long-term exposure to air pollution and asthma and allergies, both in adults and children, and to identify knowledge gaps for future research. The chapter also discusses the evidence of the impacts of climate change on air pollution as well as the possible interactions between air pollution, climate change, and allergens.

Published
2023

26. Heavy metals and diminished ovarian reserve: single-exposure and mixture analyses amongst women consulting in French fertility centres

Author

Génard-Walton, Maximilien, Warembourg, Charline, Duros, Solène, Ropert-Bouchet, Martine, Lefebvre, Tiphaine, Guivarc'H-Levêque, Anne, Le Martelot, Marie-Therese, Jacquemin, Bénédicte, Cordier, Sylvaine, Costet, Nathalie, Multigner, Luc, Garlantézec, Ronan, Institut de recherche en santé, environnement et travail (Irset), Université d'Angers (UA)-Université de Rennes (UR)-École des Hautes Études en Santé Publique [EHESP] (EHESP)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Structure Fédérative de Recherche en Biologie et Santé de Rennes ( Biosit : Biologie - Santé - Innovation Technologique ), CHU Pontchaillou [Rennes], Centre hospitalier universitaire de Nantes (CHU Nantes), Clinique mutualiste La Sagesse, Centre Hospitalier Régional Universitaire de Brest (CHRU Brest), and The study was funded by the Fondation de France (grant number 2014-50537 and 00110196) and the French Biomedicine Agency (2016).

Subjects
mixtures, reproductive outcomes, [SDV]Life Sciences [q-bio], General Earth and Planetary Sciences, [SDV.BDLR]Life Sciences [q-bio]/Reproductive Biology, [SDV.SPEE]Life Sciences [q-bio]/Santé publique et épidémiologie, heavy metals, environmental epidemiology, female fertility, chemical exposures, General Environmental Science
Abstract

International audience; RESEARCH QUESTION: Do heavy metals affect the risk of diminished ovarian reserve (DOR) in women of reproductive age? DESIGN: A total of 139 cases and 153 controls were included between 2016 and 2020. The participants were aged between 18 and 40 years and attended consultations for couple infertility in one of four fertility centres in western France. Cases of DOR were defined as women with an antral follicle count less than 7, anti-Müllerian hormone levels 1.1 ng/ml or less, or both. Controls were frequency matched on age groups and centres, and were women with normal ovarian reserve evaluations, no malformations and menstrual cycles between 26 and 35 days. Heavy metals (lead, mercury, cadmium and chromium) were measured in whole blood at inclusion. Single-exposure associations were examined with multivariable logistic regressions adjusted on potential confounders. Mixture effects were investigated with quantile g-computation and Bayesian kernel machine regression (BKMR). RESULTS: Chromium as a continuous exposure was significantly associated with DOR in unadjusted models (OR 2.07, 95% CI 1.04 to 4.13) but the association was no longer significant when confounders were controlled for (adjusted OR 2.75, 95% CI 0.88 to 8.60). Similarly, a statistically significant association was observed for the unadjusted second tercile of cadmium exposure (OR 1.87, 95% CI 1.06 to 3.30); however, this association was no longer statistically significant after adjustment. None of the other associations tested were statistically significant. Quantile g-computation and BKMR both yielded no significant change of risk of DOR for the mixture of metals, with no evidence of interaction. CONCLUSIONS: Weak signals that some heavy metals could be associated with DOR were detected. These findings should be replicated in other studies.

Published
2022

27. Associations of prenatal exposure to outdoor PM2.5 and NO2 with childhood respiratory symptoms [presented at an ISEE annual meeting]

Author

Patlán-Hernández, Alan Ricardo, Audureau, Etienne, Lepeule, Johanna, Bertin, Mélanie, Epaud, Ralph, Lanone, Sophie, Warembourg, Charline, Monfort, Christine, Chevrier, Cécile, Jacquemin, Bénédicte, École des Hautes Études en Santé Publique [EHESP] (EHESP), Département Méthodes quantitatives en santé publique (METIS), Centre de Recherches sur l'Action Politique en Europe (ARENES), and Université de Rennes (UR)-Institut d'Études Politiques [IEP] - Rennes-École des Hautes Études en Santé Publique [EHESP] (EHESP)-Centre National de la Recherche Scientifique (CNRS)

Subjects
Allergic diseases, Prenatal exposure, Air pollution, [SDV.SPEE]Life Sciences [q-bio]/Santé publique et épidémiologie, Children health
Abstract

International audience; Background and aim: Prenatal and early life exposures to air pollution have been shown to play an important role in the development of childhood respiratory and allergic diseases. Nitrogen dioxide (NO2) has been associated with increased paediatric asthma incidence, while prenatal exposure to fine particulate matter (PM2.5) has chronic and adverse effects in lung development and respiratory health. The aim of the study was to assess the associations of prenatal exposure to air pollutants with the prevalence of respiratory symptoms, asthma, allergic rhinitis, and eczema in children. Methods: We selected 2150 children from the PELAGIE Cohort in Brittany, France, that were followed-up at 2, 6 and 12 years old. Parents reported children's respiratory health history, family lifestyle behaviours and children’s immediate environment through standardized and validated questionnaires. Concentrations of PM2.5 and NO2 were modelled during the pregnancy at residential address. We used logistic regression models to assess the associations per one increase of an interquartile range (IQR), adjusted by sex, parents smoking during pregnancy, environmental tobacco smoke of children and children smoking (at 12). Results Prenatal concentrations of NO2 were 20.04±6.33μg/m3 (IQR=2.48) and PM2.5 10.24 ;1.17 g/m3 (IQR=1.59). Prenatal exposure to higher NO2 concentrations was associated with increased odds of wheezing episodes at the age of 2 years [odds ratio (OR) = 1.26; 95% confidence interval (CI):1.00–2.61] and higher odds of suffering asthma at 12 years old [OR=1.33; 95%CI: 0.97–1.82]. Overall, higher exposure to NO2 and PM2.5 during the prenatal period showed associations with increased odds of sneezing, wheezing and asthma attacks during childhood; however, these associations were at the limit of statistical significance. Conclusion: Prenatal exposures to ambient PM2.5 and NO2 seem associated with higher risk of respiratory and allergic diseases in children even at relatively low levels of air pollution concentrations.

Published
2022

28. Long-term air pollution exposure, greenspace and health-related quality of life in the ECRHS study

Author

Boudier, Anne, primary, Markevych, Iana, additional, Jacquemin, Bénédicte, additional, Abramson, Michael J., additional, Accordini, Simone, additional, Forsberg, Bertil, additional, Fuertes, Elaine, additional, Garcia-Aymerich, Judith, additional, Heinrich, Joachim, additional, Johannessen, Ane, additional, Leynaert, Bénédicte, additional, Pin, Isabelle, additional, and Siroux, Valérie, additional

Published
2022
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30. Indoor visible moulds and rhinitis in adults: The EGEA study

Author

Orsi, Laurent, primary, Savouré, Marine, additional, Bousquet, Jean, additional, Jacquemin, Bénédicte, additional, Siroux, Valérie, additional, Jaakkola, Maritta S., additional, Jaakkola, Jouni J. K., additional, Leynaert, Bénédicte, additional, and Nadif, Rachel, additional

Published
2022
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35. Association between long-term ambient air pollution exposure and handgrip strength change in the French CONSTANCES cohort

Author

Burte, Emilie, primary, Zare Sakhvidi, Mohammad Javad, additional, Lafontaine, Antoine, additional, Lequy, Emeline, additional, Artaud, Fanny, additional, Berr, Claudine, additional, Canonico, Marianne, additional, Elbaz, Alexis, additional, de Hoogh, Kees, additional, Vienneau, Danielle, additional, Goldberg, Marcel, additional, Zins, Marie, additional, and Jacquemin, Bénédicte, additional

Published
2022
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36. Association between greenspace exposure and different domains of cognitive function in the French CONSTANCES cohort

Author

Ramos, Ana, primary, Zare Sakhvidi, Mohammad Javad, additional, Lafontaine, Antoine, additional, Dadvand, Payam, additional, de Hoogh, Kees, additional, Lequy, Emeline, additional, Letellier, Noémie, additional, Mortamais, Marion, additional, Ozguler, Anna, additional, Vienneau, Danielle, additional, Goldberg, Marcel, additional, Zins, Marie, additional, Berr, Claudine, additional, and Jacquemin, Bénédicte, additional

Published
2022
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42. Greenspace exposure and children behavior: A systematic review

Author

Zare Sakhvidi, Mohammad Javad, primary, Knobel, Pablo, additional, Bauwelinck, Mariska, additional, de Keijzer, Carmen, additional, Boll, Lilian Marie, additional, Spano, Giuseppina, additional, Ubalde-Lopez, Monica, additional, Sanesi, Giovanni, additional, Mehrparvar, Amir Houshang, additional, Jacquemin, Bénédicte, additional, and Dadvand, Payam, additional

Published
2022
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44. LongITools: Dynamic longitudinal exposome trajectories in cardiovascular and metabolic noncommunicable diseases

Author

IRAS OH Epidemiology Chemical Agents, dIRAS RA-2, dIRAS RA-I&I RA, Ronkainen, Justiina, Nedelec, Rozenn, Atehortua, Angelica, Balkhiyarova, Zhanna, Cascarano, Anna, Ngoc Dang, Vien, Elhakeem, Ahmed, van Enckevort, Esther, Goncalves Soares, Ana, Haakma, Sido, Halonen, Miia, Heil, Katharina F, Heiskala, Anni, Hyde, Eleanor, Jacquemin, Bénédicte, Keikkala, Elina, Kerckhoffs, Jules, Klåvus, Anton, Kopinska, Joanna A, Lepeule, Johanna, Marazzi, Francesca, Motoc, Irina, Näätänen, Mari, Ribbenstedt, Anton, Rundblad, Amanda, Savolainen, Otto, Simonetti, Valentina, de Toro Eadie, Nina, Tzala, Evangelia, Ulrich, Anna, Wright, Thomas, Zarei, Iman, d'Amico, Enrico, Belotti, Federico, Brunius, Carl, Castleton, Christopher, Charles, Marie-Aline, Gaillard, Romy, Hanhineva, Kati, Hoek, Gerard, Holven, Kirsten B, Jaddoe, Vincent W V, Kaakinen, Marika A, Kajantie, Eero, Kavousi, Maryam, Lakka, Timo, Matthews, Jason, Piano Mortari, Andrea, Vääräsmäki, Marja, Voortman, Trudy, Webster, Claire, Zins, Marie, Atella, Vincenzo, Bulgheroni, Maria, Chadeau-Hyam, Marc, Conti, Gabriella, Evans, Jayne, Felix, Janine F, Heude, Barbara, Järvelin, Marjo-Riitta, Kolehmainen, Marjukka, Landberg, Rikard, Lekadir, Karim, Parusso, Stefano, Prokopenko, Inga, de Rooij, Susanne R, Roseboom, Tessa, Swertz, Morris, Timpson, Nicholas, Ulven, Stine M, Vermeulen, Roel, Juola, Teija, Sebert, Sylvain, IRAS OH Epidemiology Chemical Agents, dIRAS RA-2, dIRAS RA-I&I RA, Ronkainen, Justiina, Nedelec, Rozenn, Atehortua, Angelica, Balkhiyarova, Zhanna, Cascarano, Anna, Ngoc Dang, Vien, Elhakeem, Ahmed, van Enckevort, Esther, Goncalves Soares, Ana, Haakma, Sido, Halonen, Miia, Heil, Katharina F, Heiskala, Anni, Hyde, Eleanor, Jacquemin, Bénédicte, Keikkala, Elina, Kerckhoffs, Jules, Klåvus, Anton, Kopinska, Joanna A, Lepeule, Johanna, Marazzi, Francesca, Motoc, Irina, Näätänen, Mari, Ribbenstedt, Anton, Rundblad, Amanda, Savolainen, Otto, Simonetti, Valentina, de Toro Eadie, Nina, Tzala, Evangelia, Ulrich, Anna, Wright, Thomas, Zarei, Iman, d'Amico, Enrico, Belotti, Federico, Brunius, Carl, Castleton, Christopher, Charles, Marie-Aline, Gaillard, Romy, Hanhineva, Kati, Hoek, Gerard, Holven, Kirsten B, Jaddoe, Vincent W V, Kaakinen, Marika A, Kajantie, Eero, Kavousi, Maryam, Lakka, Timo, Matthews, Jason, Piano Mortari, Andrea, Vääräsmäki, Marja, Voortman, Trudy, Webster, Claire, Zins, Marie, Atella, Vincenzo, Bulgheroni, Maria, Chadeau-Hyam, Marc, Conti, Gabriella, Evans, Jayne, Felix, Janine F, Heude, Barbara, Järvelin, Marjo-Riitta, Kolehmainen, Marjukka, Landberg, Rikard, Lekadir, Karim, Parusso, Stefano, Prokopenko, Inga, de Rooij, Susanne R, Roseboom, Tessa, Swertz, Morris, Timpson, Nicholas, Ulven, Stine M, Vermeulen, Roel, Juola, Teija, and Sebert, Sylvain

Published
2022

45. Long-term air pollution exposure, greenspace and health-related quality of life in the ECRHS study

Author

Boudier, Anne, Markevych, Iana, Jacquemin, Bénédicte, Abramson, Michael J., Accordini, Simone, Forsberg, Bertil, Fuertes, Elaine, Garcia-Aymerich, Judith, Heinrich, Joachim, Johannessen, Ane, Leynaert, Bénédicte, Pin, Isabelle, Siroux, Valérie, Boudier, Anne, Markevych, Iana, Jacquemin, Bénédicte, Abramson, Michael J., Accordini, Simone, Forsberg, Bertil, Fuertes, Elaine, Garcia-Aymerich, Judith, Heinrich, Joachim, Johannessen, Ane, Leynaert, Bénédicte, Pin, Isabelle, and Siroux, Valérie

Abstract

BACKGROUND: Associations of long-term exposure to air pollution and greenspace with health-related quality of life (HRQOL) are poorly studied and few studies have accounted for asthma-rhinitis status. OBJECTIVE: To assess the associations of air pollution and greenspace with HRQOL and whether asthma and/or rhinitis modify these associations. METHODS: The study was based on the participants in the second (2000-2002, n = 6542) and third (2011-2013, n = 3686) waves of the European Community Respiratory Health Survey (ECRHS) including 19 centres. The mean follow-up time was 11.3 years. HRQOL was assessed by the SF-36 Physical and Mental Component Summary scores (PCS and MCS). NO2, PM2.5 and PM10 annual concentrations were estimated at the residential address from existing land-use regression models. Greenspace around the residential address was estimated by the (i) mean of the Normalized Difference Vegetation Index (NDVI) and by the (ii) presence of green spaces within a 300 m buffer. Associations of each exposure variable with PCS and MCS were assessed by mixed linear regression models, accounting for the multicentre design and repeated data, and adjusting for potential confounders. Analyses were stratified by asthma-rhinitis status. RESULTS: The mean (SD) age of the ECRHS-II and III participants was 43 (7.1) and 54 (7.2) years, respectively, and 48 % were men. Higher NO2, PM2.5 and PM10 concentrations were associated with lower MCS (regression coefficients [95%CI] for one unit increase in the inter-quartile range of exposures were -0.69 [-1.23; -0.15], -1.79 [-2.88; -0.70], -1.80 [-2.98; -0.62] respectively). Higher NDVI and presence of forests were associated with higher MCS. No consistent associations were observed for PCS. Similar association patterns were observed regardless of asthma-rhinitis status. CONCLUSION: European adults who resided at places with higher air pollution and lower greenspace were more likely to have lower mental component of HRQOL. Asthma or

Published
2022
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46. Association Between Short-term Exposure to Ultrafine Particles and Mortality in Eight European Urban Areas

Author

Stafoggia, Massimo, Schneider, Alexandra, Cyrys, Josef, Samoli, Evangelia, Andersen, Zorana Jovanovic, Bedada, Getahun Bero, Bellander, Tom, Cattani, Giorgio, Eleftheriadis, Konstantinos, Faustini, Annunziata, Hoffmann, Barbara, Jacquemin, Bénédicte, Katsouyanni, Klea, Massling, Andreas, Pekkanen, Juha, Perez, Noemi, Peters, Annette, Quass, Ulrich, Yli-Tuomi, Tarja, and Forastiere, Francesco

Published
2017
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47. Indoor visible moulds and rhinitis in adults: The EGEA study.

Author

Orsi, Laurent, Savouré, Marine, Bousquet, Jean, Jacquemin, Bénédicte, Siroux, Valérie, Jaakkola, Maritta S., Jaakkola, Jouni J. K., Leynaert, Bénédicte, and Nadif, Rachel

Subjects
RHINITIS, BRONCHIAL spasm
Abstract

The stronger mould-rhinitis association observed in participants without asthma as compared to those with ever asthma could be related to the avoidance of mould exposure among ever-asthmatics, or to the hypothesis that rhinitis and rhinitis asthma multimorbidity represent distinct diseases with different risk factors. As we focused on current rhinitis, we considered all participants who had had rhinitis symptoms in the past 12 months regardless of the duration of the symptoms, and participants who reported non-current rhinitis were excluded from the analyses. Although rhinitis is among the most common diseases worldwide,[1] few studies have investigated among adults the association between past and current exposure to indoor mould, a modifiable environmental factor and current rhinitis.[[2]] Furthermore, even if rhinitis and asthma often coexist, the potential modifying impact of asthma on this association has never been studied. [Extracted from the article]

Published
2023
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