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6. Pharmacist Interventions for Medication Adherence: Community Guide Economic Reviews for Cardiovascular Disease

Author

Jacob, Verughese, primary, Reynolds, Jeffrey A., additional, Chattopadhyay, Sajal K., additional, Hopkins, David P., additional, Therrien, Nicole L., additional, Jones, Christopher D., additional, Durthaler, Jeffrey M., additional, Rask, Kimberly J., additional, Cuellar, Alison E., additional, Clymer, John M., additional, and Kottke, Thomas E., additional

Published
2022
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7. Systematic Review of Self-Measured Blood Pressure Monitoring With Support: Intervention Effectiveness and Cost

Author

Shantharam, Sharada S., primary, Mahalingam, Mallika, additional, Rasool, Aysha, additional, Reynolds, Jeffrey A., additional, Bhuiya, Aunima R., additional, Satchell, Tyra D., additional, Chapel, John M., additional, Hawkins, Nikki A., additional, Jones, Christopher D., additional, Jacob, Verughese, additional, and Hopkins, David P., additional

Published
2022
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9. Engaging Community Health Workers to Increase Cancer Screening: A Community Guide Systematic Economic Review

Author

Jacob Verughese, Sharon Attipoe-Dorcoo, Yinan Peng, Donatus U. Ekwueme, Sajal K. Chattopadhyay, Community Preventive Services Task Force, and Susan A. Sabatino

Subjects
medicine.medical_specialty, Epidemiology, Colorectal cancer, Cost-Benefit Analysis, Uterine Cervical Neoplasms, Context (language use), 01 natural sciences, 03 medical and health sciences, 0302 clinical medicine, Breast cancer, Cancer screening, medicine, Humans, Mass Screening, 030212 general & internal medicine, 0101 mathematics, health care economics and organizations, Mass screening, Early Detection of Cancer, Cervical cancer, Community Health Workers, business.industry, 010102 general mathematics, Public Health, Environmental and Occupational Health, medicine.disease, Quality-adjusted life year, Family medicine, Economic evaluation, Female, Quality-Adjusted Life Years, business, Colorectal Neoplasms
Abstract

Context The Community Preventive Services Task Force recommends engaging community health workers to increase breast, cervical, and colorectal cancer screenings on the basis of strong evidence of effectiveness. This systematic review examines the economic evidence of these interventions. Evidence acquisition A systematic literature search was performed with a search period through April 2019 to identify relevant economic evaluation studies. All monetary values were adjusted to 2018 U.S. dollars, and the analysis was completed in 2019. Evidence synthesis A total of 19 studies were included in the final analysis with 3 on breast cancer, 5 on cervical cancer, 9 on colorectal cancer, and 2 that combined costs for breast and cervical cancers and for breast, cervical, and colorectal cancers. For cervical cancer screening, 2 U.S. studies reported incremental cost per quality-adjusted life year saved of $762 and $34,405. For colorectal cancer screening, 2 U.S. studies reported both a negative incremental cost and an increase in quality-adjusted life years saved with colonoscopy screening. Conclusions Engaging community health workers to increase cervical and colorectal cancer screenings is cost effective on the basis of estimated incremental cost-effectiveness ratios that were less than the conservative $50,000 per quality-adjusted life year threshold. In addition, quality-adjusted life years saved from colorectal screening with colonoscopy were associated with net healthcare cost savings.

Published
2020

10. Economics of Community Health Workers for Chronic Disease: Findings From Community Guide Systematic Reviews

Author

Jacob, Verughese, primary, Chattopadhyay, Sajal K., additional, Hopkins, David P., additional, Reynolds, Jeffrey A., additional, Xiong, Ka Zang, additional, Jones, Christopher D., additional, Rodriguez, Betsy J., additional, Proia, Krista K., additional, Pronk, Nicolaas P., additional, Clymer, John M., additional, and Goetzel, Ron Z., additional

Published
2019
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11. Capital stock estimates for major sectors and disaggregated manufacturing in selected OECD countries

Author

Jacob, Verughese, Sharma, Subhash C., and Grabowski, Richard

Subjects
Manufacturing industry -- Securities, Capital stock -- Analysis, Business, Business, general, Economics, Organisation for Economic Co-operation and Development
Abstract

I. INTRODUCTION It is impossible to conceive of any economic enterprise that does not utilize the aid of machines and equipment in its production activity, whether it be in agriculture, [...]

Published
1997

13. Increasing Coverage of Appropriate Vaccinations: A Community Guide Systematic Economic Review

Author

Jacob, Verughese, Chattopadhyay, Sajal K., Hopkins, David P., Morgan, Jennifer Murphy, Pitan, Adesola A., and Clymer, John

Subjects
House Calls, Immunization Programs, Cost-Benefit Analysis, Reminder Systems, Vaccination, Humans, Immunization, Article, United States
Abstract

Population-level coverage for immunization against many vaccine-preventable diseases remains below optimal rates in the U.S. The Community Preventive Services Task Force recently recommended several interventions to increase vaccination coverage based on systematic reviews of the evaluation literature. The present study provides the economic results from those reviews.A systematic review was conducted (search period, January 1980 through February 2012) to identify economic evaluations of 12 interventions recommended by the Task Force. Evidence was drawn from included studies; estimates were constructed for the population reach of each strategy, cost of implementation, and cost per additional vaccinated person because of the intervention. Analyses were conducted in 2014.Reminder systems, whether for clients or providers, were among the lowest-cost strategies to implement and the most cost effective in terms of additional people vaccinated. Strategies involving home visits and combination strategies in community settings were both costly and less cost effective. Strategies based in settings such as schools and MCOs that reached the target population achieved additional vaccinations in the middle range of cost effectiveness.The interventions recommended by the Task Force differed in reach, cost, and cost effectiveness. This systematic review presents the economic information for 12 effective strategies to increase vaccination coverage that can guide implementers in their choice of interventions to fit their local needs, available resources, and budget.

Published
2016

14. Economics of Team-based Care in Controlling Blood Pressure: A Community Guide Systematic Review

Author

Jacob, Verughese, Chattopadhyay, Sajal K., Thota, Anilkrishna B., Proia, Krista K., Njie, Gibril, Hopkins, David P., Finnie, Ramona K.C., Pronk, Nicolaas P., and Kottke, Thomas E.

Subjects
Cost-Benefit Analysis, Patient-Centered Care, Hypertension, Humans, Health Care Costs, Quality-Adjusted Life Years, Article, United States
Abstract

High blood pressure is an important risk factor for cardiovascular disease and stroke, the leading cause of death in the U.S., and a substantial national burden through lost productivity and medical care. A recent Community Guide systematic review found strong evidence of effectiveness of team-based care in improving blood pressure control. The objective of the present review is to determine from the economic literature whether team-based care for blood pressure control is cost beneficial or cost effective.Electronic databases of papers published January 1980-May 2012 were searched to find economic evaluations of team-based care interventions to improve blood pressure outcomes, yielding 31 studies for inclusion.In analyses conducted in 2012, intervention cost, healthcare cost averted, benefit-to-cost ratios, and cost effectiveness were abstracted from the studies. The quality of estimates for intervention and healthcare cost from each study were assessed using three elements: intervention focus on blood pressure control, incremental estimates in the intervention group relative to a control group, and inclusion of major cost-driving elements in estimates. Intervention cost per unit reduction in systolic blood pressure was converted to lifetime intervention cost per quality-adjusted life-year (QALY) saved using algorithms from published trials.Team-based care to improve blood pressure control is cost effective based on evidence that 26 of 28 estimates of $/QALY gained from ten studies were below a conservative threshold of $50,000. This finding is salient to recent U.S. healthcare reforms and coordinated patient-centered care through formation of Accountable Care Organizations.

Published
2015

15. Economics of Self-Measured Blood Pressure Monitoring: A Community Guide Systematic Review

Author

Jacob, Verughese, primary, Chattopadhyay, Sajal K., additional, Proia, Krista K., additional, Hopkins, David P., additional, Reynolds, Jeffrey, additional, Thota, Anilkrishna B., additional, Jones, Christopher D., additional, Lackland, Daniel T., additional, Rask, Kimberly J., additional, Pronk, Nicolaas P., additional, Clymer, John M., additional, and Goetzel, Ron Z., additional

Published
2017
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18. Reducing Recreational Sedentary Screen Time

Author

Ramsey Buchanan, Leigh, primary, Rooks-Peck, Cherie R., additional, Finnie, Ramona K.C., additional, Wethington, Holly R., additional, Jacob, Verughese, additional, Fulton, Janet E., additional, Johnson, Donna B., additional, Kahwati, Leila C., additional, Pratt, Charlotte A., additional, Ramirez, Gilbert, additional, Mercer, Shawna L., additional, and Glanz, Karen, additional

Published
2016
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19. Economics of Team-based Care in Controlling Blood Pressure

Author

Jacob, Verughese, primary, Chattopadhyay, Sajal K., additional, Thota, Anilkrishna B., additional, Proia, Krista K., additional, Njie, Gibril, additional, Hopkins, David P., additional, Finnie, Ramona K.C., additional, Pronk, Nicolaas P., additional, and Kottke, Thomas E., additional

Published
2015
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24. The Effectiveness of Group-Based Comprehensive Risk-Reduction and Abstinence Education Interventions to Prevent or Reduce the Risk of Adolescent Pregnancy, Human Immunodeficiency Virus, and Sexually Transmitted Infections

Author

Chin, Helen B., primary, Sipe, Theresa Ann, additional, Elder, Randy, additional, Mercer, Shawna L., additional, Chattopadhyay, Sajal K., additional, Jacob, Verughese, additional, Wethington, Holly R., additional, Kirby, Doug, additional, Elliston, Donna B., additional, Griffith, Matt, additional, Chuke, Stella O., additional, Briss, Susan C., additional, Ericksen, Irene, additional, Galbraith, Jennifer S., additional, Herbst, Jeffrey H., additional, Johnson, Robert L., additional, Kraft, Joan M., additional, Noar, Seth M., additional, Romero, Lisa M., additional, and Santelli, John, additional

Published
2012
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26. Legislations and policies to expand mental health and substance abuse benefits in health insurance plans: a community guide systematic economic review.

Author

Jacob V, Qu S, Chattopadhyay S, Sipe TA, Knopf JA, Goetzel RZ, Finnie R, and Thota AB

Subjects
Cost-Benefit Analysis, Humans, Insurance Coverage economics, Insurance Coverage legislation & jurisprudence, Insurance, Health economics, Insurance, Health legislation & jurisprudence, Policy, Substance-Related Disorders economics, Substance-Related Disorders therapy, United States, Insurance, Psychiatric economics, Insurance, Psychiatric legislation & jurisprudence, Mental Health, Mental Health Services economics, Mental Health Services legislation & jurisprudence
Abstract

Background: Health insurance plans have historically limited the benefits for mental health and substance abuse (MH/SA) services compared to benefits for physical health services. In recent years, legislative and policy initiatives in the U.S. have been taken to expand MH/SA health insurance benefits and achieve parity with physical health benefits. The relevance of these legislations for international audiences is also explored, particularly for the European context., Aims of the Study: This paper reviews the evidence of costs and economic benefits of legislative or policy interventions to expand MH/SA health insurance benefits in the U.S. The objectives are to assess the economic value of the interventions by comparing societal cost to societal benefits, and to determine impact on costs to insurance plans resulting from expansion of these benefits., Methods: The search for economic evidence covered literature published from January 1950 to March 2011 and included evaluations of federal and state laws or rules that expanded MH/SA benefits as well as voluntary actions by large employers. Two economists screened and abstracted the economic evidence of MH/SA benefits legislation based on standard economic and actuarial concepts and methods., Results: The economic review included 12 studies: eleven provided evidence on cost impact to health plans, and one estimated the effect on suicides. There was insufficient evidence to determine if the intervention was cost-effective or cost-saving. However, the evidence indicates that MH/SA benefits expansion did not lead to any substantial increase in costs to insurance plans, measured as a percentage of insurance premiums., Discussion and Limitations: This review is unable to determine the overall economic value of policies that expanded MH/SA insurance benefits due to lack of cost-effectiveness and cost-benefit studies, predominantly due to the lack of evaluations of morbidity and mortality outcomes. This may be remedied in time when long-term MH/SA patient-level data becomes available to researchers. A limitation of this review is that legislations considered here have been superseded by recent legislations that have stronger and broader impacts on MH/SA benefits within private and public insurance: Mental Health Parity and Addiction Equity Act of 2008 (MHPAEA) and the Patient Protection and Affordable Care Act of 2010 (ACA)., Implications for Future Research: Economic assessments over the long term such as cost per QALY saved and cost-benefit will be feasible as more data becomes available from plans that implemented recent expansions of MH/SA benefits. Results from these evaluations will allow a better estimate of the economic impact of the interventions from a societal perspective. Future research should also evaluate the more downstream effects on business decisions about labor, such as effects on hiring, retention, and the offer of health benefits as part of an employee compensation package. Finally, the economic effect of the far reaching ACA of 2010 on mental health and substance abuse prevalence and care is also a subject for future research.

Published
2015

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