The VDD/R pacing is accepted as an alternative to DDD/R pacing in patients with atrioventricular conduction block (AVB) and intact sinus node function.To determine the relationship between parameters obtained during assessment of the patient for the implantation procedure, using electrocardiographic (ECG) and echocardiographic (ECHO) data, and the effectiveness of AV synchronisation.The study involved a group of 65 patients (43 males, 22 females), aged 66.6 + 12.7 with clinically significant disturbances of AV conduction, who did not reveal symptoms of concomitant abnormalities in sinus node automaticity. Selected ECG and ECHO parameters were studied prior to the implantation procedure. Repeat examinations were done at 3-4 days and at 1, 3, 6 and 12 months after the procedure. The effectiveness of AV synchronisation (PAS) has been estimated by event counter read-out and ECG Holter monitoring.In 74% patients (subgroup A) synchronisation was highly effective (PAS _ 95%); in the remaining 26% subjects (subgroup B) PAS occasionally fell below 95%. In subgroup B, the P wave was longer than that in subgroup A (105 +/- 16 vs. 92 _ 13 ms; p0.05). The dimensions of the right and left heart chambers were greater in subgroup B. Patients in subgroup B had lower ejection fraction (49.4 +/- 13.7% in B vs. 58.2 +/- 11.3% in A) and revealed symptoms of heart failure. The following cut-off values for each echocardiographic and electrocardiographic parameter predisposing to PAS95% during VDD/R pacing ('undersensing') were identified: RVEDd26 mm, RVESd24 mm, LVEDd59 mm, LVESd37.3 mm, APD LA44 mm, SID RA52 mm, LMD RA48 mm, RAvol54 ml, RAarea19 cm2, SID LA57 mm, LMD LA46 mm, EF52%, P wave width100 ms. Significant predictors of PAS95% in the univariate analysis were RVEDd, RVESd, LVEDd, LMD RA, SID RA, RAvol, RAarea, EF, and in the multivariate analysis RVEDd, RVESd, LMD RA, RAarea, EF.Selected parameters obtained from ECG (P wave width) and echo examinations are correlated with effective AV synchronisation. Enlargement of the right and left heart chambers (atrial, ventricular), reduction of the ejection fraction and congestive heart failure are associated with impaired AV synchronisation in VDD/R pacemakers. In multivariate analysis, only the higher dimensions of the right ventricle and atrium and the lower ejection fraction of the left ventricle were significantly associated with the PAS95%.