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Due to the growing demand for food of animal origin, traditional production schemes have become obsolete, causing producers to look for new alternatives to increase productivity. Among the alternatives, the application of antibiotics in feed has become popular for improving animal performance, but this has led to the emergence of resistant microorganisms. Thus, the objective of this work was to evaluate the antimicrobial resistance profile of 37 pathogens isolated from swine and chickens intended for human consumption identified as Salmonella and E. coli to antibiotics used in human medicine through the disk diffusion technique; namely: amikacin 30 μg, amoxicillin-clavulanic acid 30 μg, ampicillin 10 μg, azithromycin 15 μg, cephalexin 30 μg, colistin 10 μg, ceftriaxone 30 μg, ciprofloxacin 5 μg, doxycycline 30 μg, streptomycin 10 μg, 10 μg, gentamicin meropenem 10 μg, norfloxacin 10 μg, penicillin G 10 IU, trimethoprim-sulfamethoxazole 25 μg, and vancomycin 30 μg. Some antibiotics recurrently used to treat serious infections showed low efficacy against the analyzed isolates; Among these antibiotics with little efficiency, vancomycin and penicillin G stood out. Vancomycin had an inhibitory effect in only two isolates, one of which showed partial resistance to the antibiotic. Penicillin G showed a partial inhibitory effect in most of the isolates tested, and 13 isolates showed total resistance to the antibiotic. The results showed that most of the bacterial isolates tested showed total or partial resistance to almost all antibiotics. From the analysis of the results, it was possible to perceive that the bacteria present in the food production chain showed a high profile of antimicrobial resistance, a fact that can cause damage to the health of the consumer. [ABSTRACT FROM AUTHOR]