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1. AVALIAÇÃO DE TAXA DE RESPOSTA COMPLETA EM PACIENTES PORTADORES DE LINFOMA DE HODGKIN CLÁSSICO AO TÉRMINO DO TRATAMENTO DE PRIMEIRA LINHA BASEADO EM SCORE PROGNÓSTICO E PET (POSITRON EMISSION TOMOGRAPHY) INTERIM: ANÁLISE DE UMA INSTITUIÇÃO PRIVADA

Author

J.M. Almeida, R.T. Centrone, D.F. Dias, R.S.A. Silva, A.A. Silva, P.M.O. Teixeira, C.M. Campos, M. Bellesso, M.A.F. Aranha, and K.S. Serafim

Subjects
Diseases of the blood and blood-forming organs, RC633-647.5
Published
2020
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2. Development and evaluation of a novel subunit vaccine for Mycoplasma gallisepticum

Author

L. Moura, J. Dohms, J.M. Almeida, P.S. Ferreira, C.P. Biffi, and R.G. Backes

Subjects
avaliação, avicultura, desenvolvimento, micoplasmas, vacina, Animal culture, SF1-1100
Abstract

Adhesion proteins from Mycoplasma gallisepticum (MG) encoded by cytadhesion genes mgc1 and mgc2 were cloned into plasmid vectors and transformed into E. coli. Seventeen groups of specific-pathogen free (SPF), birds at four weeks of age were used to inoculate these two proteins (MGC1 and MGC2) mixed into an oil emulsion creating a novel MG vaccine. Six different protein concentrations (50, 100, 200, 400, 800, and 1000µg/bird) were tested with two equal concentration doses at four and seven weeks of age. In addition, many control groups were needed such as bacterin, membrane, no vaccine or challenge, oil emulsion alone, and no vaccine but challenged. Three weeks following the second vaccination, 50% of the birds in each treatment group were challenged with MG strain S6. The remaining birds were left as contacts to verify protection against horizontal transmission. All birds were bled before vaccinations, challenge and euthanasia. Birds were negative for MG at the first vaccination, as shown by serum plate agglutination test. At necropsy, tissue samples (trachea, lungs, and air sacs) were collected for histopathological examination. Swabs from trachea were used for PCR analysis. ELISA results showed a strong immune response to both protein preparations and almost the same response level for different doses tested, proving the immunogenic features of MGC1 and MGC2. However, humoral responses failed to prevent MG infection and disease when challenged as demonstrated by PCR and histopathology. MGC1 contact birds showed some degree of infection by PCR analysis. In addition, histopathological and ELISA results suggest that contact birds did not have enough time to develop lesions and to mount an immune response.

Published
2012
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3. A multi-country test of brief reappraisal interventions on emotions during the COVID-19 pandemic

Author

Wang, K. Goldenberg, A. Dorison, C.A. Miller, J.K. Uusberg, A. Lerner, J.S. Gross, J.J. Agesin, B.B. Bernardo, M. Campos, O. Eudave, L. Grzech, K. Ozery, D.H. Jackson, E.A. Garcia, E.O.L. Drexler, S.M. Jurković, A.P. Rana, K. Wilson, J.P. Antoniadi, M. Desai, K. Gialitaki, Z. Kushnir, E. Nadif, K. Bravo, O.N. Nauman, R. Oosterlinck, M. Pantazi, M. Pilecka, N. Szabelska, A. van Steenkiste, I.M.M. Filip, K. Bozdoc, A.I. Marcu, G.M. Agadullina, E. Adamkovič, M. Roczniewska, M. Reyna, C. Kassianos, A.P. Westerlund, M. Ahlgren, L. Pöntinen, S. Adetula, G.A. Dursun, P. Arinze, A.I. Arinze, N.C. Ogbonnaya, C.E. Ndukaihe, I.L.G. Dalgar, I. Akkas, H. Macapagal, P.M. Lewis, S. Metin-Orta, I. Foroni, F. Willis, M. Santos, A.C. Mokady, A. Reggev, N. Kurfali, M.A. Vasilev, M.R. Nock, N.L. Parzuchowski, M. Espinoza Barría, M.F. Vranka, M. Kohlová, M.B. Ropovik, I. Harutyunyan, M. Wang, C. Yao, E. Becker, M. Manunta, E. Kaminski, G. Marko, D. Evans, K. Lewis, D.M.G. Findor, A. Landry, A.T. Aruta, J.J.B. Ortiz, M.S. Vally, Z. Pronizius, E. Voracek, M. Lamm, C. Grinberg, M. Li, R. Valentova, J.V. Mioni, G. Cellini, N. Chen, S.-C. Zickfeld, J. Moon, K. Azab, H. Levy, N. Karababa, A. Beaudry, J.L. Boucher, L. Collins, W.M. Todsen, A.L. van Schie, K. Vintr, J. Bavolar, J. Kaliska, L. Križanić, V. Samojlenko, L. Pourafshari, R. Geiger, S.J. Beitner, J. Warmelink, L. Ross, R.M. Stephen, I.D. Hostler, T.J. Azouaghe, S. McCarthy, R. Szala, A. Grano, C. Solorzano, C.S. Anjum, G. Jimenez-Leal, W. Bradford, M. Pérez, L.C. Cruz Vásquez, J.E. Galindo-Caballero, O.J. Vargas-Nieto, J.C. Kácha, O. Arvanitis, A. Xiao, Q. Cárcamo, R. Zorjan, S. Tajchman, Z. Vilares, I. Pavlacic, J.M. Kunst, J.R. Tamnes, C.K. von Bastian, C.C. Atari, M. Sharifian, M.H. Hricova, M. Kačmár, P. Schrötter, J. Rahal, R.-M. Cohen, N. FatahModarres, S. Zrimsek, M. Zakharov, I. Koehn, M.A. Esteban-Serna, C. Calin-Jageman, R.J. Krafnick, A.J. Štrukelj, E. Isager, P.M. Urban, J. Silva, J.R. Martončik, M. Očovaj, S.B. Šakan, D. Kuzminska, A.O. Djordjevic, J.M. Almeida, I.A.T. Ferreira, A. Lazarevic, L.B. Manley, H. Ricaurte, D.Z. Monteiro, R.P. Etabari, Z. Musser, E. Dunleavy, D. Chou, W. Godbersen, H. Ruiz-Fernández, S. Reeck, C. Batres, C. Kirgizova, K. Muminov, A. Azevedo, F. Alvarez, D.S. Butt, M.M. Lee, J.M. Chen, Z. Verbruggen, F. Ziano, I. Tümer, M. Charyate, A.C.A. Dubrov, D. Tejada Rivera, M.C.M.C. Aberson, C. Pálfi, B. Maldonado, M.A. Hubena, B. Sacakli, A. Ceary, C.D. Richard, K.L. Singer, G. Perillo, J.T. Ballantyne, T. Cyrus-Lai, W. Fedotov, M. Du, H. Wielgus, M. Pit, I.L. Hruška, M. Sousa, D. Aczel, B. Szaszi, B. Adamus, S. Barzykowski, K. Micheli, L. Schmidt, N.-D. Zsido, A.N. Paruzel-Czachura, M. Bialek, M. Kowal, M. Sorokowska, A. Misiak, M. Mola, D. Ortiz, M.V. Correa, P.S. Belaus, A. Muchembled, F. Ribeiro, R.R. Arriaga, P. Oliveira, R. Vaughn, L.A. Szwed, P. Kossowska, M. Czarnek, G. Kielińska, J. Antazo, B. Betlehem, R. Stieger, S. Nilsonne, G. Simonovic, N. Taber, J. Gourdon-Kanhukamwe, A. Domurat, A. Ihaya, K. Yamada, Y. Urooj, A. Gill, T. Čadek, M. Bylinina, L. Messerschmidt, J. Kurfalı, M. Adetula, A. Baklanova, E. Albayrak-Aydemir, N. Kappes, H.B. Gjoneska, B. House, T. Jones, M.V. Berkessel, J.B. Chopik, W.J. Çoksan, S. Seehuus, M. Khaoudi, A. Bokkour, A. El Arabi, K.A. Djamai, I. Iyer, A. Parashar, N. Adiguzel, A. Kocalar, H.E. Bundt, C. Norton, J.O. Papadatou-Pastou, M. De la Rosa-Gomez, A. Ankushev, V. Bogatyreva, N. Grigoryev, D. Ivanov, A. Prusova, I. Romanova, M. Sarieva, I. Terskova, M. Hristova, E. Kadreva, V.H. Janak, A. Schei, V. Sverdrup, T.E. Askelund, A.D. Pineda, L.M.S. Krupić, D. Levitan, C.A. Johannes, N. Ouherrou, N. Say, N. Sinkolova, S. Janjić, K. Stojanovska, M. Stojanovska, D. Khosla, M. Thomas, A.G. Kung, F.Y.H. Bijlstra, G. Mosannenzadeh, F. Balci, B.B. Reips, U.-D. Baskin, E. Ishkhanyan, B. Czamanski-Cohen, J. Dixson, B.J.W. Moreau, D. Sutherland, C.A.M. Chuan-Peng, H. Noone, C. Flowe, H. Anne, M. Janssen, S.M.J. Topor, M. Majeed, N.M. Kunisato, Y. Yu, K. Daches, S. Hartanto, A. Vdovic, M. Anton-Boicuk, L. Forbes, P.A.G. Kamburidis, J. Marinova, E. Nedelcheva-Datsova, M. Rachev, N.R. Stoyanova, A. Schmidt, K. Suchow, J.W. Koptjevskaja-Tamm, M. Jernsäther, T. Olofsson, J.K. Bialobrzeska, O. Marszalek, M. Tatachari, S. Afhami, R. Law, W. Antfolk, J. Žuro, B. Van Doren, N. Soto, J.A. Searston, R. Miranda, J. Damnjanović, K. Yeung, S.K. Krupić, D. Hoyer, K. Jaeger, B. Ren, D. Pfuhl, G. Klevjer, K. Corral-Frías, N.S. Frias-Armenta, M. Lucas, M.Y. Torres, A.O. Toro, M. Delgado, L.G.J. Vega, D. Solas, S.Á. Vilar, R. Massoni, S. Frizzo, T. Bran, A. Vaidis, D.C. Vieira, L. Paris, B. Capizzi, M. Coelho, G.L.H. Greenburgh, A. Whitt, C.M. Tullett, A.M. Du, X. Volz, L. Bosma, M.J. Karaarslan, C. Sarıoğuz, E. Allred, T.B. Korbmacher, M. Colloff, M.F. Lima, T.J.S. Ribeiro, M.F.F. Verharen, J.P.H. Karekla, M. Karashiali, C. Sunami, N. Jaremka, L.M. Storage, D. Habib, S. Studzinska, A. Hanel, P.H.P. Holford, D.L. Sirota, M. Wolfe, K. Chiu, F. Theodoropoulou, A. Ahn, E.R. Lin, Y. Westgate, E.C. Brohmer, H. Hofer, G. Dujols, O. Vezirian, K. Feldman, G. Travaglino, G.A. Ahmed, A. Li, M. Bosch, J. Torunsky, N. Bai, H. Manavalan, M. Song, X. Walczak, R.B. Zdybek, P. Friedemann, M. Rosa, A.D. Kozma, L. Alves, S.G. Lins, S. Pinto, I.R. Correia, R.C. Babinčák, P. Banik, G. Rojas-Berscia, L.M. Varella, M.A.C. Uttley, J. Beshears, J.E. Thommesen, K.K. Behzadnia, B. Geniole, S.N. Silan, M.A. Maturan, P.L.G. Vilsmeier, J.K. Tran, U.S. Izquierdo, S.M. Mensink, M.C. Sorokowski, P. Groyecka-Bernard, A. Radtke, T. Adoric, V.C. Carpentier, J. Özdoğru, A.A. Joy-Gaba, J.A. Hedgebeth, M.V. Ishii, T. Wichman, A.L. Röer, J.P. Ostermann, T. Davis, W.E. Suter, L. Papachristopoulos, K. Zabel, C. Ebersole, C.R. Chartier, C.R. Mallik, P.R. Urry, H.L. Buchanan, E.M. Coles, N.A. Primbs, M.A. Basnight-Brown, D.M. IJzerman, H. Forscher, P.S. Moshontz, H.

Abstract

The COVID-19 pandemic has increased negative emotions and decreased positive emotions globally. Left unchecked, these emotional changes might have a wide array of adverse impacts. To reduce negative emotions and increase positive emotions, we tested the effectiveness of reappraisal, an emotion-regulation strategy that modifies how one thinks about a situation. Participants from 87 countries and regions (n = 21,644) were randomly assigned to one of two brief reappraisal interventions (reconstrual or repurposing) or one of two control conditions (active or passive). Results revealed that both reappraisal interventions (vesus both control conditions) consistently reduced negative emotions and increased positive emotions across different measures. Reconstrual and repurposing interventions had similar effects. Importantly, planned exploratory analyses indicated that reappraisal interventions did not reduce intentions to practice preventive health behaviours. The findings demonstrate the viability of creating scalable, low-cost interventions for use around the world. Protocol registration: The stage 1 protocol for this Registered Report was accepted in principle on 12 May 2020. The protocol, as accepted by the journal, can be found at https://doi.org/10.6084/m9.figshare.c.4878591.v1 © 2021, The Author(s), under exclusive licence to Springer Nature Limited.

Published
2021

4. AVALIAÇÃO DE TAXA DE RESPOSTA COMPLETA EM PACIENTES PORTADORES DE LINFOMA DE HODGKIN CLÁSSICO AO TÉRMINO DO TRATAMENTO DE PRIMEIRA LINHA BASEADO EM SCORE PROGNÓSTICO E PET (POSITRON EMISSION TOMOGRAPHY) INTERIM: ANÁLISE DE UMA INSTITUIÇÃO PRIVADA

Author

C.M. Campos, K. S. Serafim, Renato Centrone, P.M.O. Teixeira, Daniela Ferreira Dias, A.A. Silva, Milton A. F. Aranha, R.S.A. Silva, Marcelo Bellesso, and J.M. Almeida

Subjects
business.industry, lcsh:RC633-647.5, Immunology and Allergy, Medicine, Hematology, lcsh:Diseases of the blood and blood-forming organs, business, Nuclear medicine
Published
2020

6. PND58 Multiple Sclerosis in Portugal - Clinical and Economic IMPACT of Ocrelizumab

Author

J.M. Almeida, Björn Vandewalle, I. Monteiro, A.V. Salgado, P. Martins, C. Capela, S. Vargas, G. Marcelli, João José Cerqueira, and C. Ferreira

Subjects
medicine.medical_specialty, business.industry, Health Policy, Multiple sclerosis, Public Health, Environmental and Occupational Health, medicine, Ocrelizumab, Economic impact analysis, medicine.disease, business, Intensive care medicine, medicine.drug
Published
2020
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8. Contributors

Author

M. Aiash, M. Alazab, J.M. Almeida, L. Arantes, Y. Bocchi, G.A. Borges, A. Bourdena, A. Carnielli, A. Capozzoli, T. Cerquitelli, C.S.F.S. Celes, M. Chinnici, V. Cristea, F.D. da Cunha, C. Dobre, A.P.G. Ferreira, C.F.R. Geyer, J. Gustedt, S.L. Hernane, M. Imran, N. Javaid, Z.A. Khan, V. Leithardt, A.A.F. Loureiro, D. Mahmood, E. Markakis, G. Mastorakis, C.X. Mavromoustakis, B.-C. Mocanu, W. Moreira, V.F.S. Mota, D. Negru, J.B.B. Neto, A.C. Olivieri, S. Pal, E. Pallis, E.G. Pereira, R. Pereira, M.S. Piscitelli, F. Pop, U. Qasim, A.I.J.T. Ribeiro, G. Rizzo, C.O. Rolim, A.G.d.M. Rossetto, P. Sens, G. Serale, T.H. Silva, J. Sliwa, P.O.S. Vaz de Melo, and M. Zhanikeev

Published
2016
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9. Enterobactérias associadas a adultos de Musca domestica (Linnaeus, 1758) (Diptera: Muscidae) e Chrysomya megacephala (Fabricius, 1754) (Diptera: Calliphoridae) no Jardim Zoológico, Rio de Janeiro Enterobacteria associated to adults of Musca domestica (Linnaeus, 1758) (Diptera: Muscidae) and Chrysomya megacephala (Fabricius, 1754) (Diptera: Calliphoridae) at the Zoo of Rio de Janeiro, Brazil

Author

V.C. Oliveira, J.M. D’Almeida, I.V. Abalem de Sá, J.R. Mandarino, and C.A. Solari

Subjects
animal structures, Zoo, Chrysomya megacephala, fungi, dípteros muscóides, enterobactérias, Musca domestica, lcsh:Animal culture, jardim zoológico, enterobacteria, muscoids diptera, lcsh:SF1-1100
Abstract

Enterobactérias foram identificadas em adultos de Musca domestica (Linnaeus, 1758) (Diptera: Muscidae) e Chrysomya megacephala (Fabricius, 1754) (Diptera: Calliphoridae). Ambas as espécies foram capturadas no Jardim Zoológico da cidade do Rio de Janeiro e tiveram a superfície externa do corpo lavada e o sistema digestivo dissecado, para análise bacteriológica. Identificaram-se Escherichia coli, Citrobacter sp., Proteus mirabilis, Morganella sp., Klebsiella sp., Pseudomonas sp., Enterobacter sp. e Salmonella Agona. P. mirabilis foi o isolado bacteriano mais freqüente. Em duas amostragens (8%) de C. megacephala, isolou-se Salmonella Agona. As amostras de E. coli não foram enteropatogênicas. M. domestica e C. megacephala são potenciais veiculadoras de bactérias causadoras de enterites em humanos e animais.Enterobacteria were identified in adults of Musca domestica (Linnaeus, 1758) (Diptera: Muscidae) and Chrysomya megacephala (Fabricius, 1754) (Diptera: Calliphoridae). Both species were captured in the Zoo of Rio de Janeiro. They had their external body surface washed and their digestive system dissected for bacteriological analysis. Escherichia coli, Citrobacter sp., Proteus mirabilis, Morganella sp., Klebsiella sp., Pseudomonas sp., Enterobacter sp. and Salmonella serovar Agona were isolated in the samples. P. mirabilis was the species most frequent isolated. Strains of Salmonella Agona were isolated from two samples (8%) of C. megacephala. Enteropathogenic E. coli was not isolated. M. domestica and C. megacephala showed themselves as potential vectors of agents related to enteric diseases in humans and other animals.

Published
2006

10. Causes of mortality of seabirds stranded at the Northeastern coast of Brazil

Author

Daniela B. Mariani, Bruno J.M. Almeida, Andrei D.M. Febrônio, Jociery E. Vergara-Parente, Francisco A.L. Souza, and Fábio S. Mendonça

Subjects
Seabirds stranded, wild avian diseases, wildlife conservation, mortality, Brazil, Veterinary medicine, SF600-1100
Abstract

ABSTRACT: The aim of this work was to determine the main species of stranded seabirds at the Northeastern coast of Brazil in addition to the most frequent causes of stranding and mortality. The study was conducted in a monitored area for three years (2012-2014), from the coastline of south Alagoas through north coast of Bahia encompassing 254km of coast. The seabirds found alive during the monitoring were sent to rehabilitation, clinically examined and the carcasses were removed, necropsied and histopathologically analyzed. A total of 1.347 seabirds were found stranded. Of these, 378 were found alive and sent to rehabilitation. From the 969 dead seabirds 806 were unsuitable for necropsy, being only 163 submitted to necropsy and histopathological analysis. Calonectris borealis, Puffinus gravis and Puffinus puffinus were the main seabirds stranded in the studied area. Most stranding occurred from March to June with an increase during April and May for the most species of seabirds. The main clinical signs of stranded seabirds consisted of inappetence, apathy, low body score, hypothermia, flying or movement difficulty and prolonged recumbency. Natural causes followed by infectious diseases and anthropogenic environmental factors were the main causes of death of seabirds stranded on the Northeastern coast of Brazil.

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12. Hyperprolactinaemia as a Result of Immaturity or Regression: The Concept of Maternal Subroutine

Author

Luís G. Sobrinho and J.M. Almeida-Costa

Subjects
Pregnancy, Maternal deprivation, Psychosomatics, Hyperprolactinaemia, Physiology, General Medicine, medicine.disease, Obesity, Prolactin, Developmental psychology, Psychiatry and Mental health, Clinical Psychology, medicine, medicine.symptom, Psychology, Pathological, Weight gain, Applied Psychology
Abstract

Pathological hyperprolactinaemia (PH) is significantly associated with: (1) paternal deprivation during childhood, (2) depression, (3) non-specific symptoms including obesity and weight gain. The clinical onset of the symptoms often follows pregnancy or a loss. Prolactin is an insulin antagonist which does not promote weight gain. Hyperprolactinaemia and increased metabolic efficiency are parts of a system of interdependent behavioural and metabolic mechanisms necessary for the care of the young. We call this system, which is available as a whole package, maternal subroutine (MS). An important number of cases of PH are due to activation of the MS that is not induced by pregnancy. The same occurs in surrogate maternity and in some animal models. Most women with PH developed a malignant symbiotic relationship with their mothers in the setting of absence, alcoholism or devaluation of the father. These women may regress to early developmental stages to the point that they identify themselves both with their lactating mother and with the nursing infant as has been found in psychoanalysed patients and in the paradigmatic condition of pseudopregnancy. Such regression can be associated with activation of the MS. Prolactinomas represent the extreme of the spectrum of PH and may result from somatic mutations occurring in hyperstimulated lactotrophs.

Published
1992
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