113 results on '"J. J. Taboada"'
Search Results
2. European West Coast atmospheric rivers: A scale to characterize strength and impacts
- Author
-
J. J. Taboada, Raquel Nieto, Gonzalo Miguez-Macho, Jorge Eiras-Barca, Alexandre M. Ramos, F. Martin Ralph, Luis Gimeno, Francina Dominguez, Marta Vázquez, and Iago Algarra
- Subjects
Atmospheric Science ,010504 meteorology & atmospheric sciences ,Scale (ratio) ,Frequency of occurrence ,Geography, Planning and Development ,0207 environmental engineering ,2501.06 Dinámica Atmosférica ,Precipitation ,02 engineering and technology ,lcsh:QC851-999 ,Management, Monitoring, Policy and Law ,01 natural sciences ,West coast ,020701 environmental engineering ,0105 earth and related environmental sciences ,Series (stratigraphy) ,Grid cell ,Atmospheric river ,Atmospheric rivers ,2502 Climatología ,Scale ,Impacts ,Climatology ,Period (geology) ,Environmental science ,lcsh:Meteorology. Climatology ,2501.10 Estructura Atmosférica ,2501.22 Física de las Precipitaciones - Abstract
This manuscript applies the recently-created atmospheric river intensity and impacts scale (AR Scale) to the European continent. The AR Scale uses an Eulerian perspective based solely upon the time series of integrated vapor transport (IVT) over a given geographic location (often represented by a model or reanalysis “grid cell”). The scale assigns events with persistent, strong IVT at that location to one of five levels (AR1 to AR5), or if the IVT is too weak or short-lived it is determined not to be an AR. AR1 events are primarily beneficial, AR2, 3 and 4 include a mix of beneficial and hazardous impacts, while AR5s are primarily hazardous. The frequency of occurrence, the associated probability of anomalous precipitation and the amount of precipitation explained by each AR rank are provided across Europe for the extended winter season (from October through March). AR1 and AR2 events are the most frequent and explain most of the observed precipitation, but they are associated with a low probability of extreme rainfall. Although AR3, AR4 and AR5 events are much less frequent, and normally provide a smaller fraction of annual precipitation, they are associated with a high probability of extreme rainfall. These results show remarkable variability among the different regions of the European continent. This manuscript also provides an AR detection catalog over Europe for the period 1980–2019, and a simplified version of the algorithm used to rank the events from AR1 to AR5 Financiado para publicación en acceso aberto: Universidade de Vigo/CISUG Xunta de Galicia | Ref. ED481B 2018/069 Xunta de Galicia | Ref. ED481B 2018/062 Ministerio de Economía y Competitividad | Ref. CGL2015-65141-R Xunta de Galicia | Ref. ED431C 2017/64-GRC Fundação para a Ciência e Tecnologia | Ref. CEECIND / 00027/2017 Fundação para a Ciência e Tecnologia | Ref. PTDC / CTA-MET / 29233/2017 Agencia Estatal de Investigación | Ref. RTI2018-095772-B-I00
- Published
- 2021
3. MERLIN: una nueva herramienta para la predicción del riesgo de inundaciones en la demarcación hidrográfica Galicia-Costa
- Author
-
J. J. Taboada, Jerónimo Puertas, Ignacio Fraga, Laura Fernández, Luis Cea, Sonia Botana, Belén Quinteiro, Santiago Salsón, Guillermo Fernández-García, and Gonzalo Mosqueira
- Subjects
010504 meteorology & atmospheric sciences ,Discharge data ,Flood risk management ,0207 environmental engineering ,Soil infiltration ,02 engineering and technology ,01 natural sciences ,Two stages ,Early warning system ,Hindcast ,Predicción ,Gestión de riesgo de inundación ,020701 environmental engineering ,TC1501-1800 ,0105 earth and related environmental sciences ,Hydrology ,Flood myth ,Hydraulic engineering ,Floods ,Ocean engineering ,Inundación ,inundación, predicción, gestión de riesgo de inundación ,Environmental science ,Flood hazard ,Stage (hydrology) ,TC1-978 ,Forecasting - Abstract
[EN] This article presents MERLIN, a tool for flood hazard evaluation, which forecasts discharges and water depths in flood prone areas of the Galicia Costa district. The warning system operates in two stages. During the hindcast stage, hydrological models of the basins included in the system assimilate hydro-meteorological data in order to characterize soil infiltration capacity. During the forecast stage, hydrological models are fed with meteorological predictions and discharge forecasts along the basins. Forecasted discharges define boundary conditions of hydraulic models, which compute the flood extent and the water depths over the upcoming days. The performance of MERLIN was evaluated in 4 areas using discharge data from the winter months of 2019-2020. Results proved MERLIN’s ability of predicting the discharges observed afterwards., [ES] Este artículo presenta MERLIN, una nueva herramienta para estimar el riesgo de inundaciones a partir de predicciones de caudales y calados en Áreas de Riesgo Potencial Significativo de Inundaciones (ARPSIS) de la demarcación hidrográfica Galicia-Costa. El sistema MERLIN opera en dos fases. Durante una primera fase de inicialización, modelos hidrológicos de las cuencas incluidas en el sistema asimilan datos hidro-meteorológicos para caracterizar la capacidad de infiltración del terreno. Durante la fase de predicción, los modelos hidrológicos previamente inicializados se alimentan con predicciones meteorológicas para determinar los caudales esperados durante los próximos días. Las predicciones de caudal alimentan a modelos hidráulicos de las ARPSIS que determinan los calados y la extensión de zonas inundadas. El funcionamiento de MERLIN se evaluó en 4 cuencas piloto a partir de los caudales registrados durante los temporales del invierno del 2019-2020, mostrando una buena capacidad de predecir los valores posteriormente observados., El desarrollo del sistema MERLIN y el resto de trabajos presentados en este artículo fue posible gracias a la financiación aportada por Augas de Galicia dentro del Convenio de colaboración entre Augas de Galicia e a Fundación de Enxeñería Civil de Galicia para a mellora do sistema de alerta temperá de risco de inundación na demarcación hidrográfica Galicia-costa.
- Published
- 2021
4. Sensitivity of CHIMERE to changes in model resolution and chemistry over the northwestern Iberian Peninsula
- Author
-
María Luz Macho, Nuria Gallego Fernández, Paula Costa Tomé, J. J. Taboada, Swen Brands, Marcos Tesouro Montecelo, Christina Otero, Pablo Enrique Carracedo García, Guillermo Fernández-García, Anabela Neto Venancio, Pedro Costa, and Anthony David Saunders Estévez
- Subjects
geography ,geography.geographical_feature_category ,Integrated Forecast System ,Weather forecasting ,Terrain ,Particulates ,Atmospheric sciences ,computer.software_genre ,chemistry.chemical_compound ,chemistry ,Peninsula ,Weather Research and Forecasting Model ,Nitrogen dioxide ,Emission inventory ,computer - Abstract
Here, the capability of the chemical weather forecasting model CHIMERE (version 2017r4) to reproduce summertime surface ozone, particulate matter and nitrogen dioxide concentrations in complex terrain is investigated. The study area is the northwestern Iberian Peninsula, where both coastal and mountain climates can be found in direct vicinity and a large fraction of the land area is covered by forests. Fed by lateral boundary conditions from the ECMWF Composition Integrated Forecast System, meteorological data from the Weather Research and Forecasting Model (WRF) and the HTAP v2.2 emission inventory, CHIMERE's performance compared to observations is tested with a range of sensitivity experiments, exploring the role of horizontal and vertical resolution and the effects of applying distinct chemistry mechanisms. Using a high horizontal and vertical resolution yields the most balanced verification results. If both the daily maximum and minimum values are important for the given application, then the full Melchior mechanism should be used. If, however, the daily maxima are considered more important than the minima, SAPRC should be used instead. In any case, model performance for nitrogen dioxide is clearly not satisfactory for our study region, probably indicating deficiencies in the emission inventory.
- Published
- 2019
- Full Text
- View/download PDF
5. An Integrated Perspective of the Operational Forecasting System in Rías Baixas (Galicia, Spain) with Observational Data and End-Users
- Author
-
Pedro Montero, J. J. Taboada, Sabela Regueiro, Swen Brands, Pedro Costa, and Anabela Venâncio
- Subjects
End user ,Ocean forecasting ,0211 other engineering and technologies ,02 engineering and technology ,Operational forecasting ,Atmospheric model ,021001 nanoscience & nanotechnology ,Natural resource ,Anthropogenic stress ,Climatology ,Weather Research and Forecasting Model ,Web page ,Environmental science ,0210 nano-technology ,021101 geological & geomatics engineering - Abstract
Rias Baixas is a coastal region located in northwestern Spain (Galicia), between Cape Fisterra and the Portugal-Spain border. Its rich natural resources, which are key for the welfare of the region, are highly vulnerable to natural and anthropogenic stress. In this study, the operational ocean forecasting system developed at the meteorological agency of the Galician government (MeteoGalicia) is presented focussing on the Rias Baixas region. This system includes four models providing daily output data: the hydrodynamic models ROMS and MOHID, the atmospheric model WRF and the hydrological model SWAT. Here, MOHID’s implementation for the Rias Baixas region is described and the model’s performance with respect to observations is shown for those locations where Current-Temperature-Depth (CTD) profiles are obtained weekly by the Technological Institute for the Monitoring of the Marine Environment in Galicia (INTECMAR). Although the hydrodynamical conditions of this region are complex, the model skillfully reproduces these CTDs. The model results and derived products are publicly available through MeteoGalicia’s web page and data server (www.meteogalicia.gal).
- Published
- 2019
- Full Text
- View/download PDF
6. On the relationship between atmospheric rivers, weather types and floods in Galicia (NW Spain)
- Author
-
Alba Robles, Nieves Lorenzo, Gonzalo Miguez-Macho, J. J. Taboada, Jorge Eiras-Barca, and Universidade de Santiago de Compostela. Departamento de Física de Partículas
- Subjects
010504 meteorology & atmospheric sciences ,0208 environmental biotechnology ,02 engineering and technology ,01 natural sciences ,lcsh:TD1-1066 ,Atmosphere ,Extratropical cyclone ,Precipitation ,lcsh:Environmental technology. Sanitary engineering ,lcsh:Environmental sciences ,0105 earth and related environmental sciences ,lcsh:GE1-350 ,Flood myth ,Water vapor flux ,lcsh:QE1-996.5 ,Flooding (psychology) ,lcsh:Geography. Anthropology. Recreation ,020801 environmental engineering ,lcsh:Geology ,lcsh:G ,Climatology ,General Earth and Planetary Sciences ,Environmental science ,2501.10 Estructura Atmosférica ,2508 Hidrología ,2501.22 Física de las Precipitaciones - Abstract
Atmospheric rivers (ARs) – long and narrow structures of anomalously high water vapor flux located in the warm sector of extratropical cyclones – have been shown to be closely related to extreme precipitation and flooding. In this paper we analyze the connection between ARs and flooding in the northwestern Spanish region of Galicia under a variety of synoptic conditions represented by the so-called “weather types”, a classification of daily sea-level pressure patterns obtained by means of a simple scheme that adopts the subjective procedure of Lamb. Flood events are identified from official reports conducted by the Spanish emergency management agency (Protección Civil) from 1979 to 2010. Our results suggest that, although most flood events in Galicia do not coincide with the presence of an overhead AR, ARs are present in the majority of severe cases, particularly in coastal areas. Flood events associated with ARs are connected to cyclonic weather types with westerly and southwesterly flows, which occur mostly in winter months. The link between ARs and severe flooding is not very apparent in inland areas or during summer months, in which case heavy precipitation is usually not frontal in nature but rather convective. Nevertheless, our results show that, in general, the amount of precipitation in flood events in Galicia more than doubles when an AR is present The authors acknowledge fruitful discussions with Swen Brands and MeteoGalicia. Jorge Eiras-Barca is funded by the “Ministerio Español de Economía y Competitividad” and FEDER (EDRF) (CGL2013-45932-R). This work was partially supported by Xunta de Galicia under project “gts0005 ED431C 2017/64-GRC” Programa de Consolidación e Estruturación de Unidades de Investigación Competitivas (Grupos de Referencia Competitiva) SI
- Published
- 2018
7. Winter circulation weather types and hospital admissions for respiratory diseases in Galicia, Spain
- Author
-
M. N. Lorenzo, A. Martí, Dominic Royé, and J. J. Taboada
- Subjects
Adult ,Male ,Atmospheric Science ,010504 meteorology & atmospheric sciences ,Health, Toxicology and Mutagenesis ,Respiratory Tract Diseases ,01 natural sciences ,Young Adult ,03 medical and health sciences ,Human health ,0302 clinical medicine ,Peninsula ,medicine ,Humans ,Circulation (currency) ,030212 general & internal medicine ,Weather ,0105 earth and related environmental sciences ,geography ,geography.geographical_feature_category ,Ecology ,Middle Aged ,Seasonality ,medicine.disease ,Hospitalization ,Spain ,Anticyclone ,Climatology ,Hospital admission ,population characteristics ,Female ,Seasons ,geographic locations - Abstract
The link between various pathologies and atmospheric conditions has been a constant topic of study over recent decades in many places across the world; knowing more about it enables us to pre-empt the worsening of certain diseases, thereby optimizing medical resources. This study looked specifically at the connections in winter between respiratory diseases and types of atmospheric weather conditions (Circulation Weather Types, CWT) in Galicia, a region in the north-western corner of the Iberian Peninsula. To do this, the study used hospital admission data associated with these pathologies as well as an automatic classification of weather types. The main result obtained was that weather types giving rise to an increase in admissions due to these diseases are those associated with cold, dry weather, such as those in the east and south-east, or anticyclonic types. A second peak was associated with humid, hotter weather, generally linked to south-west weather types. In the future, this result may help to forecast the increase in respiratory pathologies in the region some days in advance.
- Published
- 2015
- Full Text
- View/download PDF
8. Trends of the Galician upwelling in the context of climate change
- Author
-
J. J. Taboada, N. Casabella, and M. N. Lorenzo
- Subjects
Ocean dynamics ,Oceanography ,Geography ,geography.geographical_feature_category ,Peninsula ,Fishing ,Climate change ,Upwelling ,Context (language use) ,Aquatic Science ,Ecology, Evolution, Behavior and Systematics - Abstract
Coastal upwelling is a phenomenon of great importance both for the study of ocean dynamics and for the development of fish production in some coastal regions. Our study region, the Galician coast, lies at the northern end of the Canary–Iberian Peninsula upwelling system. Knowing the changes provoked by climate change on this upwelling system is particularly relevant for the future of this area taking into account the social and economic importance of fishing activities in this region. In this paper we study the trends in the intensity and frequency of upwelling in the Galician coast and the expected changes in this phenomenon for the next decades using three regional models implemented within the European project ENSEMBLES. As a main result, we observe that the models show a positive trend in both the intensity and frequency of upwelling phenomenon for the future, particularly significant in spring and summer which are the seasons favorable for upwelling. In autumn and winter there are no significant changes.
- Published
- 2014
- Full Text
- View/download PDF
9. Influence of climate on grape production and wine quality in the Rías Baixas, north-western Spain
- Author
-
J. F. Lorenzo, M. N. Lorenzo, Alexandre M. Ramos, and J. J. Taboada
- Subjects
Wine ,Global and Planetary Change ,Index (economics) ,Geography ,Productivity (ecology) ,Atmospheric circulation ,Climatology ,Climate change ,Climate model ,Viticulture ,Teleconnection - Abstract
Climate exerts an important role on grape production and wine quality. For one of the main areas protected under the denomination of origin Rias Baixas, in Galicia, Spain, we explore the relationships among grape production, wine quality, rainfall and temperature for the period 1987–2005. The influence of climatic variability was analysed in terms of the relationship between the productivity of the grapevines and the main meteorological teleconnection patterns affecting the North Atlantic region. We also investigate the daily variation in atmospheric circulation through the study of the influence of weather types derived using an automated daily classification. We consider three bioclimatic indices for viticultural zoning, Winkler and Huglin, and the hydrothermic index of Branas, Bernon and Levadoux. While significant trends were identified in the Winkler and Huglin indices, there were no significant trends in the Branas, Bernon and Levadoux index, for the period 1958–2005. For the coming decades, using the scenario A1B evaluated by the regional climate models used in the ENSEMBLES project, the positive trends of Winkler and Huglin indices continue, while Branas, Bernon and Levadoux implies a negative trend. In all cases, these trends induce significant changes in the viticulture of the region.
- Published
- 2012
- Full Text
- View/download PDF
10. Predictability of the spring rainfall in Northwestern Iberian Peninsula from sea surfaces temperature of ENSO areas
- Author
-
Moncho Gómez-Gesteira, M. Nieves Lorenzo, Isabel Iglesias, and J. J. Taboada
- Subjects
Atmospheric Science ,Global and Planetary Change ,geography ,geography.geographical_feature_category ,Sea surface temperature ,La Niña ,El Niño Southern Oscillation ,Negative phase ,Peninsula ,Climatology ,Spring (hydrology) ,Period (geology) ,Predictability ,Geology - Abstract
The influence of sea surface temperature (SST) of the ocean on seasonal rainfall in Northwestern Iberian Peninsula is studied for the period 1951–2006. Seasonal correlations were calculated for all seasons and different lags applied on SST. A test for field-significance considering the properties of finiteness and interdependence of the spatial grid was applied to avoid correlations by chance. The most significant and repetitive correlation is found between SST over Equatorial Pacific and spring rainfall. The correlation is maintained for different lags, and the common area that satisfies the criteria for statistical field significance is coincident with ENSO area. A forecast scheme is developed to predict spring rainfall anomalies based in SST over ENSO area in precedent seasons. An analysis of principal components was also carried out to obtain the main modes of the Pacific Ocean and their influence on spring rainfall in NWIP. This study concludes that for the period 1951–2006 the negative phase of ENSO, “La Nina”, almost always announces dry springs in NW Iberian Peninsula. However, the positive phase of ENSO, “El Nino”, does not anticipate the appearance of wet springs.
- Published
- 2010
- Full Text
- View/download PDF
11. Sensitivity of thermohaline circulation to decadal and multidecadal variability
- Author
-
J. J. Taboada, M. N. Lorenzo, and Isabel Iglesias
- Subjects
Ecology ,Aquatic Science ,Oceanography ,Gulf Stream ,Sea surface temperature ,Effects of global warming ,Climatology ,Stream function ,Atlantic multidecadal oscillation ,Abrupt climate change ,Environmental science ,Thermohaline circulation ,Sea surface salinity ,Ecology, Evolution, Behavior and Systematics - Abstract
Lorenzo, M. N., Taboada, J. J., and Iglesias, I. 2009. Sensitivity of thermohaline circulation to decadal and multidecadal variability. – ICES Journal of Marine Science, 66: 1439–1447. In this paper, stochastic freshwater inputs with different variabilities are introduced into an Earth Model of Intermediate Complexity to study their effect on the behaviour of the thermohaline circulation (THC). The variability in the stochastic signal was set to be either decadal or multidecadal (70 years), based on intensity modulation of the El Niño-Southern Oscillation (ENSO) phenomenon. The results demonstrate a weakening of the THC in both the decadal and the multidecadal cases. This weakening results in a reduction in air surface temperature, mainly in the North Atlantic. Moreover, the 500-mb stream function also weakens. This causes lower rainfall in Western Europe, except in the areas most influenced by the Gulf Stream. Sea surface temperature is reduced significantly in the area around Greenland, whereas sea surface salinity is reduced around Greenland and in the Gulf Stream, but increased in the Labrador Sea and in Hudson Strait. The latter effects are more marked in the case where the variability of the inputs is multidecadal. The main implication of these results is that the natural decadal or multidecadal variability in freshwater inputs could have noticeable effects on the fate of the THC, which may be superimposed on the effects of climate change.
- Published
- 2009
- Full Text
- View/download PDF
12. Links between circulation weather types and teleconnection patterns and their influence on precipitation patterns in Galicia (NW Spain)
- Author
-
M. N. Lorenzo, Luis Gimeno, and J. J. Taboada
- Subjects
Atmospheric Science ,Geography ,Arctic oscillation ,Anticyclone ,North Atlantic oscillation ,Atmospheric circulation ,Synoptic scale meteorology ,Climatology ,Northern Hemisphere ,Precipitation ,Teleconnection - Abstract
An automated version of the Lamb weather type classification scheme was used to study the relationship between atmospheric circulation patterns and rainfall in the northwestern part of the Iberian Peninsula, which is an important area of crossing influences of the different teleconnection patterns of the Northern Hemisphere. We calculated the correlation between the most important teleconnection patterns that affect this area and the different types of weather circulation. In this area, anticyclone weather types are the most frequent in any part of the year. The frequency of occurrence of W and SW situations is also significant in autumn and winter. The correlation between weather types (WT) and teleconnection patterns showed that the North Atlantic Oscillation (NAO) index has significant correlations only in winter, while other patterns, such as the Eastern Atlantic (EA), have significant correlations in the other seasons. As a result of these correlations, the EA is a more relevant pattern than the NAO for describing the Galician climate throughout the year. We also calculated correlations between the North Hemisphere Annular Mode (NAM) and the different types of weather types. The NAM shows significant correlations throughout the year. Hence, the NAM is more relevant than the NAO, which is its local manifestation. Copyright © 2007 Royal Meteorological Society
- Published
- 2007
- Full Text
- View/download PDF
13. Influences of atmospheric variability on freshwater input in Galician Rías in winter
- Author
-
M. N. Lorenzo and J. J. Taboada
- Subjects
Atmospheric Science ,geography ,geography.geographical_feature_category ,010504 meteorology & atmospheric sciences ,Rain gauge ,Discharge ,0207 environmental engineering ,General Engineering ,Estuary ,02 engineering and technology ,Oceanography ,Spatial distribution ,01 natural sciences ,Atmosphere ,13. Climate action ,Climatology ,General Earth and Planetary Sciences ,Environmental science ,Hydrometeorology ,Precipitation ,020701 environmental engineering ,0105 earth and related environmental sciences ,General Environmental Science ,Teleconnection - Abstract
The influence of the preferred modes of variation of the atmosphere in the North Hemisphere on the precipitation variability was evaluated in Galicia (NW Iberian Peninsula). The special location of Galicia requires consideration of the influence of several indices that characterize the atmosphere in order to explain the variability of precipitation and consequently the flow regime of its rivers. We calculate the correlation between the precipitation data obtained from 47 rain-gauge stations covering Galicia from 1977 to 1998 and the five principal teleconnection patterns on the Atlantic area of North Hemisphere (NAO, EA, EA/WR, SCA, and POL). The results obtained show significant correlations between winter precipitation and these patterns, and clear spatial distribution of their influence within Galicia. This result could be related directly to the freshwater discharge in the different Galician Rias each winter, which would improve the hydrodynamical description of these estuaries.
- Published
- 2005
- Full Text
- View/download PDF
14. The Role of Stochastic Forcing in Climate Models: The Case of Thermohaline Circulation
- Author
-
M. N. Lorenzo, Isabel Iglesias, and J. J. Taboada
- Subjects
Climatology ,Climate system ,Environmental science ,Stochastic forcing ,Thermohaline circulation ,Climate model ,Numerical models ,Simple (philosophy) - Abstract
At present both daily and seasonal weather forecasts as well as long-term climate predictions are the result of the implementation of multiple and complex numerical models. The history of numerical models to predict the weather goes back to the 1950s and 1960s and since then computational breakthroughs have enabled us to go from simple box models to complex models that take into account a multitude of phenomena and processes occurring in the whole climate system. However despite the great strides made in recent years and great experience in the development of such models we must interpret the results taking into account the limitations and uncertainties inherent in any numerical model.
- Published
- 2012
15. Changes in present and future circulation types frequency in northwest Iberian Peninsula
- Author
-
Alexandre M. Ramos, M. N. Lorenzo, J. J. Taboada, and Luis Gimeno
- Subjects
Atmospheric Science ,Climate ,Climate Change ,Climatic Processes ,lcsh:Medicine ,Biology ,Atmospheric Circulation ,Meteorology ,Peninsula ,Computer Simulation ,Atmospheric Dynamics ,lcsh:Science ,Sea level ,Air Movements ,Climatology ,Air Pressure ,geography ,Multidisciplinary ,geography.geographical_feature_category ,Cyclonic Storms ,lcsh:R ,Europe ,Circulation (fluid dynamics) ,Anticyclone ,Earth Sciences ,lcsh:Q ,Seasons ,Air movement ,Forecasting ,Research Article ,Climate Modeling - Abstract
The aim of the work described herein was to study projection scenarios in order to find changes in the synoptic variability of the northwest Iberian Peninsula in the 21st century. To this end, we investigated the changes in the frequency of the different circulation types computed for the study area using three different models used in the IPCC 4(th) assessment report. The circulation types were computed using the procedure known as Lamb circulation types. The control simulation for the late 20th century was evaluated objectively from the results obtained using data from the NCEP/NCAR reanalysis, as to evaluate the ability of the model to reproduce the present climate. We have compared not only seasonal mean sea level pressure fields but also the mean seasonal frequency of circulation types. The results for the end of the 21st century show a decrease in the frequency of cyclonic, W, and SW circulation types in the spring and summer months. This trend also appears in the autumn, with a concomitant increase in the anticyclonic types.
- Published
- 2011
16. The state of climate in NW Iberia
- Author
-
Moncho Gómez-Gesteira, Alexandre M. Ramos, Alejandro J. C. Crespo, J.L. Gómez-Gesteira, J. J. Taboada, Raquel Nieto, Isabel Iglesias, Ines Alvarez, Luis Gimeno, David Barriopedro, Isabel F. Trigo, M. N. Lorenzo, Maite deCastro, and Fátima Espírito Santo
- Subjects
Astrofísica ,Atmospheric Science ,Atmospheric circulation ,Climate ,Sea surface temperature ,Precipitation ,Land temperature ,Synoptic systems ,Sea level rise ,Peninsula ,Synoptic scale meteorology ,Ekman transport ,Environmental Chemistry ,General Environmental Science ,geography.geographical_feature_category ,Northwest Iberia ,Física atmosférica ,Weather types ,Astronomía ,Teleconnection indices ,Geography ,North Atlantic oscillation ,Climatology ,Upwelling - Abstract
Since 1974, there has been a significant increasing trend in land and sea surface temperatures of 0.5 and 0.24 degrees C decade(-1), respectively, in the NW Iberian Peninsula. Over the same period, annual precipitation does not show any trend, although some tendencies have been detected at seasonal scales. A significant positive trend, on average of 2 cm decade(-1), was also observed in sea level rise from 1943 onwards. Ekman transport perpendicular to the coast (upwelling index) showed a decrease from 1975 to 2008 at both annual and seasonal scales. In addition, the flow of the Mino River (the main river in the area) has also decreased at a mean rate of 18 m(3) s(-1) decade(-1) since 1970. At a synoptic scale, winter cyclone frequency and winter and spring blocking activity have decreased since the 1950s, which may partially explain the winter precipitation decline and the winter and spring temperature increases. These changes in synoptic systems are also in agreement with reported trends in the dominant variability modes of atmospheric circulation affecting NW Iberia, particularly a pronounced positive trend in the North Atlantic Oscillation from the 1970s to the 1990s.
- Published
- 2011
17. Relationship between monthly rainfall in northwest Iberian Peninsula and North Atlantic sea surface temperature
- Author
-
Moncho Gómez-Gesteira, J. J. Taboada, M. N. Lorenzo, and Isabel Iglesias
- Subjects
Atmospheric Science ,geography ,Sea surface temperature ,geography.geographical_feature_category ,Peninsula ,Climatology ,Linear regression ,Period (geology) ,Environmental science ,Predictability - Abstract
This study assesses the relationship between monthly North Atlantic sea surface temperature anomalies (SSTAs) and a regional index of rainfall (NWIPR) in northwest Iberian Peninsula during the period 1951–2006 by means of the Pearson product-moment correlation. Results show a strong influence of SSTA on NWIPR in several months (February, April, May, October and December). The observed persistence of this influence up to 2-months in advance can be used for monthly predictions of rainfall. The most significant areas of the North Atlantic were clustered to be used as input variables in linear regression models. Correlations up to 0.59 between observed and predicted rainfall anomalies were obtained. Predictability ranged from 76 to 86% when considering rainfall as a discrete predictand. Copyright © 2009 Royal Meteorological Society
- Published
- 2009
- Full Text
- View/download PDF
18. The role of stochastic forcing on the behavior of thermohaline circulation
- Author
-
Isabel Iglesias, J. J. Taboada, Ines Alvarez, and M. N. Lorenzo
- Subjects
Meteorology ,General Neuroscience ,Intertropical Convergence Zone ,Northern Hemisphere ,General Biochemistry, Genetics and Molecular Biology ,Sea surface temperature ,History and Philosophy of Science ,North Atlantic oscillation ,Climatology ,Abrupt climate change ,Environmental science ,Climate model ,Thermohaline circulation ,Younger Dryas - Abstract
The nonlinear nature of the climate system suggests that its reactions to unexpected perturbations could be different from the expected ones. In nonlinear science it is recognized as a promising paradigm that stochastic fluctuations can generate order or other counterintuitive effects. Thus, noise sources, adequately coupled to a nonlinear system, may give rise to a rich new phenomenology not present in a deterministic noiseless scenario. In this review we focus attention on thermohaline circulation (THC). THC presents two modes of operation; one state shows active THC and the other inactive. Previous episodes of transitions between both states of THC observed in paleoclimatic records and the influence of this circulation on climate have resulted in detailed investigations on the dynamics of the THC. A weakening or a collapse of this current could trigger the onset of a new Younger Dryas. In this review the introduction of stochastic forcing in key parameters, both in a simple box model and in an earth model of intermediate complexity, provokes a weakening and even a shutdown of the THC. The consequences of this weakening are observed in different variables. The surface air temperature and the sea surface temperature are dominated by cooling of the Northern Hemisphere. Changes in the position of the Intertropical Convergence Zone and in precipitation are observed. There is also an intensification of the North Atlantic Oscillation values during winter. These results reinforce the necessity to consider stochastic sources in climate models to improve our understanding of the climate.
- Published
- 2008
19. Effects of the synoptic scale variability on the thermohaline circulation
- Author
-
M. N. Lorenzo, J. J. Taboada, Group of Nonlinear Physics, Faculty of Physics, Facultade de Ciencias [Campus Ourense], Universidade de Vigo, and EGU, Publication
- Subjects
010504 meteorology & atmospheric sciences ,Meteorology ,Climate change ,[SDU.STU]Sciences of the Universe [physics]/Earth Sciences ,Zonal and meridional ,[SDU.ASTR] Sciences of the Universe [physics]/Astrophysics [astro-ph] ,01 natural sciences ,Physics::Geophysics ,[PHYS.ASTR.CO]Physics [physics]/Astrophysics [astro-ph]/Cosmology and Extra-Galactic Astrophysics [astro-ph.CO] ,symbols.namesake ,Synoptic scale meteorology ,0103 physical sciences ,lcsh:Science ,010306 general physics ,Physics::Atmospheric and Oceanic Physics ,0105 earth and related environmental sciences ,[SDU.ASTR]Sciences of the Universe [physics]/Astrophysics [astro-ph] ,lcsh:QC801-809 ,lcsh:QC1-999 ,lcsh:Geophysics. Cosmic physics ,Additive white Gaussian noise ,[PHYS.ASTR.CO] Physics [physics]/Astrophysics [astro-ph]/Cosmology and Extra-Galactic Astrophysics [astro-ph.CO] ,13. Climate action ,Climatology ,[SDU.STU] Sciences of the Universe [physics]/Earth Sciences ,symbols ,Environmental science ,lcsh:Q ,Thermohaline circulation ,lcsh:Physics ,Noise (radio) - Abstract
In this paper the effect of the synoptic scale variability is analyzed using a simple atmosphere-ocean coupled model. This high frequency variability has been taken into account in the model adding white gaussian noise in variables related to zonal and meridional temperature differences. Results show that synoptic scale frequency variability on longitudinal heating contrast between land and sea can produce a collapse of thermohaline circulation when a threshold of noise is overcome. This result is significant because if synoptic scale variability in the next century increases due to the climatic change an increment of the probability of this collapse could be produced.
- Published
- 2005
20. Hydrodynamic model study of the Ria de Pontevedra under estuarine conditions
- Author
-
Paulo C. Leitão, Manuel Ruiz-Villarreal, V. Pérez-Villar, Ricardo Prego, J. J. Taboada, and Pedro Montero
- Subjects
geography ,geography.geographical_feature_category ,Residual circulation ,Baroclinity ,Flow (psychology) ,Ria de Pontevedra (Galicia, Spain) ,Estuary ,Aquatic Science ,Oceanography ,Residual ,Tidal circulation ,3-D baroclinic model ,Downwelling ,Transverse circulation ,Partially mixed estuary ,Upwelling ,Spatial variability ,Surface layer ,Geology - Abstract
13 páginas, 9 figuras, The Ria de Pontevedra is one of the Galician Rias Baixas, partially mixed estuaries on the north-west coast of the Iberian peninsula. The hydrodynamics of the rias is far from being fully understood. In this application, the hydrodynamics of the Ria de Pontevedra is studied by means of a 3-D baroclinic model. Our aim was to establish the circulation pattern driven by tide and the horizontal density gradient between river and shelf waters under estuarine conditions. The spatial variability of tidal velocities and salinities is studied. The residual component of the flow, related to transport, is described and discussed. As expected in a partially mixed estuary, a double-layered residual pattern is observed, with water flowing seaward in a surface layer and upstream in a bottom layer. A cross-channel residual flow, not described up to date, is presented., This work is part of a Ph.D thesis by M. R. Villarreal, who gratefully acknowledges the support of a predoctoral grant from the Xunta de Galicia (Spain). This research was also carried out in relation to the project ‘ La Hidrodina´mica y el Ciclo Biogeoquímico del Silicio’, financed by the Spanish Comisión Interministerial de Ciencia y Tecnología (CICYT) under the number MAR96-1782.
- Published
- 2002
21. Wind and tidal influence on water circulation in a galician ria (NW Spain)
- Author
-
Ricardo Prego, Moncho Gómez-Gesteira, P. Herbello, Maite deCastro, Vicente Pérez-Villar, J. J. Taboada, and Pedro Montero
- Subjects
Upwelling ,Galician estuary ,Westerlies ,Wind ,Aquatic Science ,Wind direction ,Oceanography ,Water circulation ,Wind speed ,Current (stream) ,Prevailing winds ,Tidal force ,Thermohaline circulation ,Breezes ,Geology - Abstract
16 páginas, 5 tablas, 17 figuras, The wind effect on water circulation was described by means of hydrodynamical and thermohaline measurements carried out in the ria of Pontevedra (NW Spain) from February to July 1998. The samples were measured both at an anchored station situated in the inner part of the ria and at other stations located in the main channel. In this way, temporal and spatial events were related. Thermohaline variables (salinity and temperature) were used to clarify the current patterns measured at the anchored station. It has been observed that there is a clear predominance of wind in the main estuary axis direction. The wind direction is strongly dependent on topography. Wind speeds higher than 4 ms 1 are able to dominate the current at surface layers, even against tidal effect. Easterly winds force water to leave the estuary at surface layers while westerly winds force water to enter it. Diurnal breezes associated with westerly winds were rarely recorded. Bottom layers were controlled by tide, except during an upwelling event., This work was partially supported by ‘ Comisión Interministerial de Ciencia y Tecnología ’, under project MAR96-1782.
- Published
- 2000
22. Modèle bidimensionnel de suivi des particules et dispersion de la pollution dans les rias de La Corogne et de Vigo (Espagne)
- Author
-
J. J. Taboada, Moncho Gómez-Gesteira, Manuel Ruiz-Villarreal, Vicente Pérez-Villar, Ramiro Neves, Pedro Montero, Paulo C. Leitão, and Ricardo Prego
- Subjects
0106 biological sciences ,Tracking model ,010504 meteorology & atmospheric sciences ,Residual currents ,Particle (ecology) ,Two-dimensional model ,Aquatic Science ,Oceanography ,Residence time (fluid dynamics) ,01 natural sciences ,Modèle bidimensionnel ,traceur passif ,Rias de Galice ,14. Life underwater ,0105 earth and related environmental sciences ,computer.programming_language ,Hydrology ,010604 marine biology & hydrobiology ,Passive tracers ,Galician rias ,Trceur passif ,Pollution ,13. Climate action ,Harbour ,Environmental science ,Circulation résiduelle ,Pollution dispersion ,computer - Abstract
11 páginas, 7 figuras, 1 tabla, [EN] A two-dimensional hydrodynamic model coupled to a particle tracking model is applied to study the dispersion processes and residence time in two Galician rias (A Coruiia and Vigo, NW Spain) under summer conditions. In A Coruiia a long residence time was found in the harbour area due to the existence of a dock, and a short one in the river area. On the contrary, in Vigo, the residence time is smaller in the harbour area, due to the Rande Strait, beyond which the river effect is negligible., [FR] Un modele hydrodynamique bidimensionel couple a un modele de suivi des particules a Ctd applique a deux rias de Galice (La Corogne et Vigo) pour Ctudier la dispersion et les temps de residence dans les deux estuaires en ttt. Dans la ria de La Corogne, le temps de residence des eaux est important dans la zone portuaire et court a l’embouchure du fleuve. L’inverse est observe dans la ria de Vigo, oti le detroit de Rande limite l’effet du fleuve.
- Published
- 1999
23. Evaluation of the seasonal variations in the residual circulation in the Ria of Vigo (NW Spain) by means of a 3D Baroclinic model
- Author
-
Moncho Gómez-Gesteira, Manuel Ruiz-Villarreal, Ricardo Prego, A. P. Santos, Vicente Pérez-Villar, J. J. Taboada, and Pedro Montero
- Subjects
3D model ,geography ,geography.geographical_feature_category ,Residual circulation ,Baroclinity ,Estuary ,Seasonal variations ,Aquatic Science ,Seasonality ,Oceanography ,medicine.disease ,Residual ,Current (stream) ,Circulation (fluid dynamics) ,Climatology ,medicine ,NW Spain ,Environmental science ,Bathymetry ,Surface runoff ,Ria of Vigo - Abstract
10 páginas, 3 tablas, 4 figuras, A 3D baroclinic model has been applied to study residual circulation in the Rı´a of Vigo (NW Spain) under different seasonal conditions. Winter, spring and non-upwelling summer conditions have been simulated. The use of a 3D model allows the spatial structure of residual circulation to be studied, both horizontaly and verticaly, and the combined effects of bathymetry, freshwater runoff, etc. to be monitored. A two-layered circulation was obtained in all situations, which is in good agreement with the partially-mixed condition of the estuary. This circulation is enhanced with increasing freshwater runoff, while its decrease makes the pattern not to be observed in the outermost part of the Rı´a. The zero residual current level depth has been estimated in all the situations, and the results have been compared to those obtained in the same conditions with a box model, finding a good agreement, J. J. Taboada is supported by Xunta de Galicia (Conselleria de Pesca) under the project ‘ Ordenacion del Espacio Maritimo Terrestre de Galicia: Modelado Informatico
- Published
- 1998
24. Seasonal Predictability of the East Atlantic Pattern from Sea Surface Temperatures
- Author
-
J. J. Taboada, M. N. Lorenzo, and Isabel Iglesias
- Subjects
Atmospheric Science ,010504 meteorology & atmospheric sciences ,Oceans and Seas ,0207 environmental engineering ,lcsh:Medicine ,02 engineering and technology ,Oceanography ,01 natural sciences ,Meteorology ,Oceans ,Linear regression ,Hindcast ,14. Life underwater ,Atmospheric Dynamics ,Predictability ,lcsh:Science ,Ocean Temperature ,020701 environmental engineering ,Boreal summer ,Atlantic Ocean ,Indian Ocean ,0105 earth and related environmental sciences ,Climatology ,Numerical Analysis ,Pacific Ocean ,Multidisciplinary ,lcsh:R ,Temperature ,Mode (statistics) ,Marine and aquatic sciences ,Earth sciences ,Sea surface temperature ,13. Climate action ,Computer Science ,Environmental science ,lcsh:Q ,Seasons ,Ocean Properties ,Research Article - Abstract
This study analyzes the influence of sea surface temperatures (SSTs) on the second mode of atmospheric variability in the north Atlantic/European sector, namely the East-Atlantic (EA) pattern, for the period 1950-2012. For this purpose, lead-lag relationships between SSTs and the EA pattern, ranging from 0 to 3 seasons, were assessed. As a main result, anomalies of the EA pattern in boreal summer and autumn are significantly related to SST anomalies in the Indo-Pacific Ocean during the preceding seasons. A statistical forecasting scheme based on multiple linear regression was used to hindcast the EA-anomalies with a lead-time of 1 to 2 months. The results of a one-year-out cross-validation approach indicate that the phases of the EA in summer and autumn can be properly hindcast.
- Published
- 2014
- Full Text
- View/download PDF
25. Spiral breakup induced by an electric current in a Belousov-Zhabotinsky medium
- Author
-
Vicente Pérez-Muñuzuri, Vicente Pérez-Villar, Alberto P. Muñuzuri, J. J. Taboada, and Moncho Gómez-Gesteira
- Subjects
Physics ,Wave propagation ,Applied Mathematics ,General Physics and Astronomy ,Statistical and Nonlinear Physics ,Mechanics ,Breakup ,Vortex ,Amplitude ,Classical mechanics ,Belousov–Zhabotinsky reaction ,Electric current ,Spiral (railway) ,Nuclear Experiment ,Mathematical Physics ,Oregonator - Abstract
Sprial breakup in the Belousov–Zhabotinsky reaction has been observed under the influence of an externally applied alternating electric current. The dynamic mechanism of this breakup is explained in the framework of this reaction. The dependence of the critical electric current amplitude on the period of the wave and on the excitability of the medium is analyzed. Spiral breakup is shown to provide a limit of validity of electric‐field‐induced drift of vortices in excitable media. Experimental results are complemented with numerical simulations provided by two‐ and three‐variable Oregonator models.
- Published
- 1994
26. Hydrography of the Pontevedra Ria: Intra-annual spatial and temporal variability in a Galician coastal system (NW Spain)
- Author
-
Moncho Gómez-Gesteira, Vicente Pérez-Villar, Andrew W. Dale, Pedro Montero, Maite deCastro, Ricardo Prego, Manuel R. Villareal, and J. J. Taboada
- Subjects
0106 biological sciences ,Atmospheric Science ,010504 meteorology & atmospheric sciences ,Water flow ,Soil Science ,Aquatic Science ,Oceanography ,01 natural sciences ,Bottom water ,Geochemistry and Petrology ,Streamflow ,Earth and Planetary Sciences (miscellaneous) ,14. Life underwater ,0105 earth and related environmental sciences ,Earth-Surface Processes ,Water Science and Technology ,geography ,Isopycnal ,geography.geographical_feature_category ,Ecology ,Discharge ,Continental shelf ,010604 marine biology & hydrobiology ,Paleontology ,Forestry ,Geophysics ,13. Climate action ,Space and Planetary Science ,Upwelling ,Environmental science ,Hydrography - Abstract
13 páginas, 9 figuras, 1 tabla, In order to ameliorate the dearth of existing scientific knowledge concerning the hydrography of the Pontevedra Ria, a systematic investigation was carried out between October 1997–98. Salinity variations were closely related to river discharge whereas bottom waters presented oceanic characteristics over the whole year. Current was controlled by tide, river discharge, and wind in the internal ria where the highest velocities were directed along the ria channel with a low transverse component. Favorable atmospheric conditions in spring induced coastal upwelling up the continental shelf. In May the upwelling was sufficiently strong to be detected in the inner ria and intensified in July and August, cooling the ria water to 12°–14°C. Upwelling ceased in September, and from November to March seawater transported by the poleward current (35.9; 15°C) was detected on the shelf. From January until March, unanticipated favorable upwelling conditions provoked an influx of poleward inside the ria. Ria intrusion of poleward water and association with occasional winter upwelling conditions has not been observed previously. Isopycnic three-dimensional (3-D) surface and 2-D isopycnal maps show that with high river runoff or intense upwelling, lower-salinity water leaves the ria near the northern margin in the surface layer. Under negative upwelling conditions, the water is partially dammed inside the ria and exits the ria when the wind speed falls. During upwelling events, ENACW penetrated the ria, especially near the southern shore. Arrival of ENACW at the northern entrance impedes the outward water flow through this mouth., This work was supported by CICYT under the Spanish project Hydrodynamic and Biogeochemical Cycle of Silicon in the Pontevedra Ria, reference MAR96-1782
27. Influence of teleconnection patterns on precipitation variability and on river flow regimes in the Miño River basin (NW Iberian Peninsula)
- Author
-
Nieves Lorenzo, J. J. Taboada, Ines Alvarez, Maite deCastro, Maria Sarmiento, and Moncho Gómez-Gesteira
- Subjects
Wet season ,Atmospheric Science ,geography.geographical_feature_category ,Atmospheric circulation ,Northern Hemisphere ,Drainage basin ,Geography ,Arctic oscillation ,Climatology ,Streamflow ,Environmental Chemistry ,Precipitation ,General Environmental Science ,Teleconnection - Abstract
The influence of the most representative winter patterns of atmospheric variation in the Northern Hemisphere on precipitation variability and on river flow regimes was evaluated for the Mino River basin (NW Iberian Peninsula). The Arctic Oscillation (AO) was also considered in order to analyze the effect of a larger-scale atmospheric mode on precipitation and river flow. Precipitation data were obtained from 22 rain-gauge stations located within the Mino River basin from 1976 to 1997, and the Mino River flow data were recorded at Frieira gauge station from 1970 to 2005. Both hydrological-year (October to September) time series were averaged for the wet season (December to February). The precipitation variability and river flow in the Mino catchment were shown to have high positive correlation. Relationships with atmospheric circulation modes show that the main pre- cipitation variability, and consequently the river-flow regimes, during winter cannot be explained by a single atmospheric pattern. The temporal evolution (1970-2005) of the correlation between the teleconnection indices and river flow averaged for 22 yr periods showed how all atmospheric patterns evolve with a different trend structure—in such a way that the most prevalent pattern depends on the chosen period of time. Moreover, the time evolution of the correlation between the AO and river flow remains more stationary than for the rest of the indices, due to its larger scale.
28. Brief cognitive tests as a decision-making tool in primary care. A population and validation study.
- Author
-
Tainta M, Iriondo A, Ecay-Torres M, Estanga A, de Arriba M, Barandiaran M, Clerigue M, Garcia-Sebastian M, Villanua J, Izagirre A, Saldias J, Aramburu A, Taboada J, Múgica J, Barandiaran A, Arrospide A, Mar J, and Martinez-Lage P
- Subjects
- Humans, Female, Male, Aged, Neuropsychological Tests, Middle Aged, Sensitivity and Specificity, Mental Status and Dementia Tests, Aged, 80 and over, Decision Making, Primary Health Care, Cognitive Dysfunction diagnosis
- Abstract
Introduction and Objectives: Brief cognitive tests (BCT) are used in primary care (PC) for the detection of cognitive impairment (CI). Still, there are little data on their diagnostic utility (DU) in a community setting. This work evaluates the DU at the population level of Fototest, T@M, AD8 questionnaire and MMSE. It provides new cut-off points (CoP) validated in a CI early detection program., Material and Methods: In the population and validation samples, the evaluation was carried out in two phases, a first of screening and administration of BCT and a second of clinical diagnosis, blinded to the results of the BCT, applying the current NIA-AA criteria. The DU of BCT in the population sample was evaluated with the area under the ROC curve (aROC). Youden index and the CoP with the best specificity that ensured a sensitivity of 80% were used to decide on the most appropriate CoP. The sensitivity, specificity, and predictive values for these CoP were calculated in the validation sample., Results: 260 participants (23.1% with CI) from the population sample and 177 (42.4% with CI) from the validation sample were included. The Fototest has the best UD at the population level (aROC 0.851), which improves with the combination of Fototest and AD8 (aROC 0.875). The proposed CoP are AD8 ≥ 1, Fototest ≤ 35, T@M ≤ 40, and MMSE ≤ 26., Conclusion: BCT are helpful in detecting CI in PC. This work supports the use of more demanding PoC., (Copyright © 2022 Sociedad Española de Neurología. Published by Elsevier España, S.L.U. All rights reserved.)
- Published
- 2024
- Full Text
- View/download PDF
29. Twist-tunable polaritonic nanoresonators in a van der Waals crystal.
- Author
-
Matveeva OG, Tresguerres-Mata AIF, Kirtaev RV, Voronin KV, Taboada-Gutiérrez J, Lanza C, Duan J, Martín-Sánchez J, Volkov VS, Alonso-González P, and Nikitin AY
- Abstract
Optical nanoresonators are key building blocks in various nanotechnological applications (e.g., spectroscopy) due to their ability to effectively confine light at the nanoscale. Recently, nanoresonators based on phonon polaritons (PhPs)-light coupled to lattice vibrations-in polar crystals (e.g., SiC, or h-BN) have attracted much attention due to their strong field confinement, high quality factors, and their potential to enhance the photonic density of states at mid-infrared (mid-IR) frequencies, where numerous molecular vibrations reside. Here, we introduce a new class of mid-IR nanoresonators that not only exhibit the extraordinary properties previously reported, but also incorporate a new degree of freedom: twist tuning, i.e., the possibility of controlling their spectral response by simply rotating the constituent material. To achieve this result, we place a pristine slab of the van der Waals (vdW) α-MoO
3 crystal, which supports in-plane hyperbolic PhPs, on an array of metallic ribbons. This sample design based on electromagnetic engineering, not only allows the definition of α-MoO3 nanoresonators with low losses (quality factors, Q, up to 200), but also enables a broad spectral tuning of the polaritonic resonances (up to 32 cm-1 , i.e., up to ~6 times their full width at half maximum, FWHM ~5 cm-1 ) by a simple in-plane rotation of the same slab (from 0 to 45°). These results open the door to the development of tunable and low-loss IR nanotechnologies, fundamental requirements for their implementation in molecular sensing, emission or photodetection applications., Competing Interests: Competing interestsThe authors declare no competing interests., (© The Author(s) 2023.)- Published
- 2023
- Full Text
- View/download PDF
30. Planar refraction and lensing of highly confined polaritons in anisotropic media.
- Author
-
Duan J, Álvarez-Pérez G, Tresguerres-Mata AIF, Taboada-Gutiérrez J, Voronin KV, Bylinkin A, Chang B, Xiao S, Liu S, Edgar JH, Martín JI, Volkov VS, Hillenbrand R, Martín-Sánchez J, Nikitin AY, and Alonso-González P
- Abstract
Refraction between isotropic media is characterized by light bending towards the normal to the boundary when passing from a low- to a high-refractive-index medium. However, refraction between anisotropic media is a more exotic phenomenon which remains barely investigated, particularly at the nanoscale. Here, we visualize and comprehensively study the general case of refraction of electromagnetic waves between two strongly anisotropic (hyperbolic) media, and we do it with the use of nanoscale-confined polaritons in a natural medium: α-MoO
3 . The refracted polaritons exhibit non-intuitive directions of propagation as they traverse planar nanoprisms, enabling to unveil an exotic optical effect: bending-free refraction. Furthermore, we develop an in-plane refractive hyperlens, yielding foci as small as λp /6, being λp the polariton wavelength (λ0 /50 compared to the wavelength of free-space light). Our results set the grounds for planar nano-optics in strongly anisotropic media, with potential for effective control of the flow of energy at the nanoscale., (© 2021. The Author(s).)- Published
- 2021
- Full Text
- View/download PDF
31. Enabling propagation of anisotropic polaritons along forbidden directions via a topological transition.
- Author
-
Duan J, Álvarez-Pérez G, Voronin KV, Prieto I, Taboada-Gutiérrez J, Volkov VS, Martín-Sánchez J, Nikitin AY, and Alonso-González P
- Abstract
Polaritons with directional in-plane propagation and ultralow losses in van der Waals (vdW) crystals promise unprecedented manipulation of light at the nanoscale. However, these polaritons present a crucial limitation: their directional propagation is intrinsically determined by the crystal structure of the host material, imposing forbidden directions of propagation. Here, we demonstrate that directional polaritons (in-plane hyperbolic phonon polaritons) in a vdW crystal (α-phase molybdenum trioxide) can be directed along forbidden directions by inducing an optical topological transition, which emerges when the slab is placed on a substrate with a given negative permittivity (4H-silicon carbide). By visualizing the transition in real space, we observe exotic polaritonic states between mutually orthogonal hyperbolic regimes, which unveil the topological origin of the transition: a gap opening in the dispersion. This work provides insights into optical topological transitions in vdW crystals, which introduce a route to direct light at the nanoscale., (Copyright © 2021 The Authors, some rights reserved; exclusive licensee American Association for the Advancement of Science. No claim to original U.S. Government Works. Distributed under a Creative Commons Attribution NonCommercial License 4.0 (CC BY-NC).)
- Published
- 2021
- Full Text
- View/download PDF
32. Developing a new Bayesian Risk Index for risk evaluation of soil contamination.
- Author
-
Albuquerque MTD, Gerassis S, Sierra C, Taboada J, Martín JE, Antunes IMHR, and Gallego JR
- Subjects
- Estuaries, Risk Assessment, Soil, Spain, Bayes Theorem, Environmental Monitoring, Metals, Heavy analysis, Soil Pollutants analysis
- Abstract
Industrial and agricultural activities heavily constrain soil quality. Potentially Toxic Elements (PTEs) are a threat to public health and the environment alike. In this regard, the identification of areas that require remediation is crucial. In the herein research a geochemical dataset (230 samples) comprising 14 elements (Cu, Pb, Zn, Ag, Ni, Mn, Fe, As, Cd, V, Cr, Ti, Al and S) was gathered throughout eight different zones distinguished by their main activity, namely, recreational, agriculture/livestock and heavy industry in the Avilés Estuary (North of Spain). Then a stratified systematic sampling method was used at short, medium, and long distances from each zone to obtain a representative picture of the total variability of the selected attributes. The information was then combined in four risk classes (Low, Moderate, High, Remediation) following reference values from several sediment quality guidelines (SQGs). A Bayesian analysis, inferred for each zone, allowed the characterization of PTEs correlations, the unsupervised learning network technique proving to be the best fit. Based on the Bayesian network structure obtained, Pb, As and Mn were selected as key contamination parameters. For these 3 elements, the conditional probability obtained was allocated to each observed point, and a simple, direct index (Bayesian Risk Index-BRI) was constructed as a linear rating of the pre-defined risk classes weighted by the previously obtained probability. Finally, the BRI underwent geostatistical modeling. One hundred Sequential Gaussian Simulations (SGS) were computed. The Mean Image and the Standard Deviation maps were obtained, allowing the definition of High/Low risk clusters (Local G clustering) and the computation of spatial uncertainty. High-risk clusters are mainly distributed within the area with the highest altitude (agriculture/livestock) showing an associated low spatial uncertainty, clearly indicating the need for remediation. Atmospheric emissions, mainly derived from the metallurgical industry, contribute to soil contamination by PTEs., (Copyright © 2017 Elsevier B.V. All rights reserved.)
- Published
- 2017
- Full Text
- View/download PDF
33. Analysis and detection of functional outliers in water quality parameters from different automated monitoring stations in the Nalón river basin (Northern Spain).
- Author
-
Piñeiro Di Blasi JI, Martínez Torres J, García Nieto PJ, Alonso Fernández JR, Díaz Muñiz C, and Taboada J
- Subjects
- Animals, Spain, Water Pollution, Chemical analysis, Rivers chemistry, Water Pollutants, Chemical analysis, Water Quality
- Abstract
The purposes and intent of the authorities in establishing water quality standards are to provide enhancement of water quality and prevention of pollution to protect the public health or welfare in accordance with the public interest for drinking water supplies, conservation of fish, wildlife and other beneficial aquatic life, and agricultural, industrial, recreational, and other reasonable and necessary uses as well as to maintain and improve the biological integrity of the waters. In this way, water quality controls involve a large number of variables and observations, often subject to some outliers. An outlier is an observation that is numerically distant from the rest of the data or that appears to deviate markedly from other members of the sample in which it occurs. An interesting analysis is to find those observations that produce measurements that are different from the pattern established in the sample. Therefore, identification of atypical observations is an important concern in water quality monitoring and a difficult task because of the multivariate nature of water quality data. Our study provides a new method for detecting outliers in water quality monitoring parameters, using turbidity, conductivity and ammonium ion as indicator variables. Until now, methods were based on considering the different parameters as a vector whose components were their concentration values. This innovative approach lies in considering water quality monitoring over time as continuous curves instead of discrete points, that is to say, the dataset of the problem are considered as a time-dependent function and not as a set of discrete values in different time instants. This new methodology, which is based on the concept of functional depth, was applied to the detection of outliers in water quality monitoring samples in the Nalón river basin with success. Results of this study were discussed here in terms of origin, causes, etc. Finally, the conclusions as well as advantages of the functional method are exposed.
- Published
- 2015
- Full Text
- View/download PDF
34. Detection of outliers in water quality monitoring samples using functional data analysis in San Esteban estuary (Northern Spain).
- Author
-
Díaz Muñiz C, García Nieto PJ, Alonso Fernández JR, Martínez Torres J, and Taboada J
- Subjects
- Models, Statistical, Multivariate Analysis, Spain, Environmental Monitoring methods, Environmental Monitoring statistics & numerical data, Estuaries, Seawater analysis, Statistics as Topic, Water Quality standards
- Abstract
Water quality controls involve large number of variables and observations, often subject to some outliers. An outlier is an observation that is numerically distant from the rest of the data or that appears to deviate markedly from other members of the sample in which it occurs. An interesting analysis is to find those observations that produce measurements that are different from the pattern established in the sample. Therefore, identification of atypical observations is an important concern in water quality monitoring and a difficult task because of the multivariate nature of water quality data. Our study provides a new method for detecting outliers in water quality monitoring parameters, using oxygen and turbidity as indicator variables. Until now, methods were based on considering the different parameters as a vector whose components were their concentration values. Our approach lies in considering water quality monitoring through time as curves instead of vectors, that is to say, the data set of the problem is considered as a time-dependent function and not as a set of discrete values in different time instants. The methodology, which is based on the concept of functional depth, was applied to the detection of outliers in water quality monitoring samples in San Esteban estuary. Results were discussed in terms of origin, causes, etc., and compared with those obtained using the conventional method based on vector comparison. Finally, the advantages of the functional method are exposed., (Copyright © 2012 Elsevier B.V. All rights reserved.)
- Published
- 2012
- Full Text
- View/download PDF
35. [Improvements in the general services of a hospital as the result of patients surveys].
- Author
-
Castelo-Zas S, Valenciano-González A, Taboada-Gómez J, and Bastida-Remetería R
- Subjects
- Humans, Spain, Hospitals standards, Patient Satisfaction statistics & numerical data
- Abstract
Objective: The progressive decrease in the level of satisfaction expressed by our patients with respect to the Hospital's Cooking and Cleaning Services highlighted the need to implement a series of measures in order to identify areas for improvement and increase the satisfaction of our patients with those services., Methodology: We reviewed the scores of patients satisfaction surveys in recent years and analysed the trends. Later, we identified the worse rated aspects, investigated the possible causes of the decrease in scores and proposed some solutions. After a feasibility analysis, we established a plan of action and implemented the accepted improvements. Finally, with the surveys of 2008 and 2009, we evaluated whether we had achieved the expected results in our patients' opinion., Results: Improvement in patient satisfaction in most of the items related to the Cooking Service: increased by 6% and 4.2%, respectively in the quantity and variety variables, and 0.5% in quality. On the other hand, the increase in Cleaning Services satisfaction was minimal, 0.9% at best., Conclusions: Obtaining direct opinions of patients can be useful when our purpose is to implement changes. Paying greater attention to particular aspects has enabled us to improve our patients' satisfaction, not only with general services but also with the overall care they received during the hospital stay., (Copyright © 2009 SECA. Published by Elsevier Espana. All rights reserved.)
- Published
- 2010
- Full Text
- View/download PDF
36. Antigen and antibody testing for the diagnosis of blastomycosis in dogs.
- Author
-
Spector D, Legendre AM, Wheat J, Bemis D, Rohrbach B, Taboada J, and Durkin M
- Subjects
- Animals, Antibodies, Fungal urine, Antifungal Agents therapeutic use, Antigens, Fungal urine, Blastomyces immunology, Blastomycosis diagnosis, Blastomycosis drug therapy, Blastomycosis immunology, Dog Diseases drug therapy, Dog Diseases urine, Dogs, Itraconazole therapeutic use, Sensitivity and Specificity, Time Factors, Antibodies, Fungal immunology, Antigens, Fungal immunology, Blastomycosis veterinary, Dog Diseases immunology, Immunoenzyme Techniques veterinary
- Abstract
Background: Early diagnosis and treatment are associated with an improved prognosis in blastomycosis. The diagnosis of blastomycosis may be missed by cytology, histopathology, culture, or serology. An enzyme immunoassay (EIA) for detection of Blastomyces dermatitidis galactomannan antigen in body fluids has been used for rapid diagnosis of blastomycosis in humans., Hypothesis: Measurement of Blastomyces antigen in urine or serum by the MVista Blastomyces antigen EIA is more sensitive than measurement of anti-Blastomyces antibodies for diagnosis of blastomycosis in dogs., Methods: Serum and urine samples from 46 dogs with confirmed blastomycosis were tested for Blastomyces antigen and serum was tested for anti-Blastomyces antibodies., Results: The sensitivity for the detection of antigen in urine was 93.5% and it was 87.0% in serum. The sensitivity of antibody detection by agar gel immunodiffusion (AGID) was 17.4% and it was 76.1% by EIA. Antigen and antibody decreased during itraconazole treatment., Conclusions and Clinical Importance: Antigen detection is a more sensitive test for diagnosis of blastomycosis than antibody testing by AGID, the only commercially available method. Antigen concentrations decreased with treatment.
- Published
- 2008
- Full Text
- View/download PDF
37. Machine learning techniques applied to the determination of road suitability for the transportation of dangerous substances.
- Author
-
Matías JM, Taboada J, Ordóñez C, and Nieto PG
- Subjects
- Accidents, Traffic prevention & control, Computing Methodologies, Expert Systems, Artificial Intelligence, Environmental Pollution prevention & control, Hazardous Substances, Safety Management, Transportation standards
- Abstract
This article describes a methodology to model the degree of remedial action required to make short stretches of a roadway suitable for dangerous goods transport (DGT), particularly pollutant substances, using different variables associated with the characteristics of each segment. Thirty-one factors determining the impact of an accident on a particular stretch of road were identified and subdivided into two major groups: accident probability factors and accident severity factors. Given the number of factors determining the state of a particular road segment, the only viable statistical methods for implementing the model were machine learning techniques, such as multilayer perceptron networks (MLPs), classification trees (CARTs) and support vector machines (SVMs). The results produced by these techniques on a test sample were more favourable than those produced by traditional discriminant analysis, irrespective of whether dimensionality reduction techniques were applied. The best results were obtained using SVMs specifically adapted to ordinal data. This technique takes advantage of the ordinal information contained in the data without penalising the computational load. Furthermore, the technique permits the estimation of the utility function that is latent in expert knowledge.
- Published
- 2007
- Full Text
- View/download PDF
38. A mathematical approach to selective scavenging of the different classes of typical atmospheric aerosols by rainout and health impact.
- Author
-
García Nieto PJ, del Coz Díaz JJ, Ordóñez Galán C, and Taboada Castro J
- Subjects
- Air Pollutants, Environmental Health, Particle Size, Risk Assessment, Aerosols, Models, Theoretical, Rain
- Abstract
In this work, initially a general mathematical framework for wet deposition processes is developed and followed by an in-depth discussion of the scavenging of material below cloud due to rain. These processes are then integrated into an overall framework focussing mainly on precipitation scavenging by rain. This work studies the scavenging efficiencies of aerosol particles within a given rain regime as a function of time by below-cloud scavenging. The health impact of aerosol before and after rain is also considered by comparing the respirable dust fractions. The well-known equations of below-cloud scavenging are applied to eight different classes of atmospheric aerosols (marine background (MB), clean continental background (CCB), average background (AB), background and aged urban plume (BAUP), background and local sources (BLS), urban average (UA), urban and freeway (UF) and central power plant (CCP)) in two precipitation regimes (drizzle and heavy rain) with one drop size distribution (DSD). From this study it is inferred that respirable dust is scavenged with relative ease by rainout. Compared with the volume of respirable aerosol average urban environment (UA) before rain roughly 5.2% remains after 18 hours of drizzle and 4% after 18 hours of heavy rain. Over a long timescale, the results show that heavy rain is more efficient than drizzle in particle scavenging.
- Published
- 2006
- Full Text
- View/download PDF
39. Transdermal methimazole treatment in cats with hyperthyroidism.
- Author
-
Hoffmann G, Marks SL, Taboada J, Hosgood GL, and Wolfsheimer KJ
- Subjects
- Administration, Cutaneous, Animals, Antithyroid Agents administration & dosage, Cat Diseases pathology, Cats, Ear, External, Female, Hyperthyroidism drug therapy, Male, Methimazole administration & dosage, Records veterinary, Retrospective Studies, Thyroxine blood, Treatment Outcome, Antithyroid Agents therapeutic use, Cat Diseases drug therapy, Hyperthyroidism veterinary, Methimazole therapeutic use
- Abstract
The objectives of this study were to assess serum thyroxine concentrations and clinical response in hyperthyroid cats to treatment with transdermal methimazole, and to determine if further investigation is indicated. Clinical and laboratory data from 13 cats with hyperthyroidism were retrospectively evaluated. Methimazole (Tapazole, Eli Lilly) was formulated in a pleuronic lecithin organogel (PLO)-based vehicle and was applied to the inner pinna of the ear at a dosage ranging from 2.5mg/cat q 24h to 10.0mg/cat q 12h. During the treatment period, cats were re-evaluated at a mean of 4.3 weeks (recheck-1), and again at a mean of 5.4 months (recheck-2). Clinical improvement was observed, and significant decreases in thyroxine concentrations were measured at recheck-1 (mean: 39.57nmol/L, SEM: 14.4, SD: 41.2) and recheck-2 (mean: 36.71nmol/L, SEM: 13.9, SD: 45.56) compared to pretreatment concentrations (mean: 97.5nmol/L, SEM: 11.42, SD: 39.5). No adverse effects were reported.
- Published
- 2003
- Full Text
- View/download PDF
40. Macular phototrauma after cataract extraction and multifocal lens implantation: case report.
- Author
-
Menezo JL, Peris-Martínez C, and Taboada Esteve J
- Subjects
- Adult, Female, Humans, Light adverse effects, Ophthalmoscopy, Radiation Injuries diagnosis, Retina pathology, Retinal Diseases diagnosis, Scotoma diagnosis, Scotoma etiology, Vision Disorders diagnosis, Vision Disorders etiology, Visual Acuity, Lens Implantation, Intraocular, Phacoemulsification, Postoperative Complications, Radiation Injuries etiology, Retina radiation effects, Retinal Diseases etiology
- Abstract
Purpose: To report a patient who developed photic injury after cataract surgery and multifocal MF4 lens implantation, Methods: A 41-year-old caucasian woman without antecedents of interest was subjected to left catarct surgery involving phacoemulsification with capsular sac implantation of a new type of multifocal lens. A coaxial light microscope was used for surgery. The operation was filmed and anterior pole photographs were obtained., Results: Two days after the operation, the patient noted a paracentral scotoma and hand movement visual acuity in the left eye. Indirect ophthalmoscopy revealed an oval, hyperpigmented macular lesion compatible with phototoxic maculopathy., Conclusions: Phototoxic injury to the macula may occur after cataract extraction. Implantation of an intraocular lens is an important factor in the producion of maculopathy, on account of its light-focusing effect on the retina. This effect was probably increased in our patient by the use of a new autofocus multifocal lens.
- Published
- 2002
- Full Text
- View/download PDF
41. Chromene chalcones from Tephrosia carrollii and the revised structure of Oaracacin.
- Author
-
Gómez-Garibay F, Arciniega MD, Céspedes CL, Taboada J, and Calderón JS
- Subjects
- Benzopyrans isolation & purification, Chalcone isolation & purification, Crystallography, X-Ray, Models, Molecular, Molecular Structure, Stereoisomerism, Benzopyrans chemistry, Chalcone chemistry, Rosales chemistry
- Abstract
The aerial parts of Tephrosia carrollii afforded two chromene chalcones. Their structures and stereochemistry were established by spectroscopic methods. The structure of oaxacacin was revised and confirmed by X-ray diffraction. In this paper, we describe the isolation of the chalcone known as "oaxacacin" and the new chalcone named epoxyobovatachalcone. The compound der. oaxacacin was found to be identical with obovatachalcone based on spectroscopic evidence and X-ray diffraction.
- Published
- 2001
- Full Text
- View/download PDF
42. In vitro cytotoxicity of flavonoids against MK2 and C6 tumour cells.
- Author
-
Sánchez I, Calderón J, Ruiz B, Tellez J, Calzada L, and Taboada J
- Subjects
- Animals, Macaca, Plant Extracts toxicity, Plant Leaves, Rats, Tumor Cells, Cultured drug effects, Apoptosis drug effects, Asteraceae, Flavonoids toxicity, Plants, Medicinal
- Abstract
The cytotoxic effect of five flavonoids isolated from the aerial parts of the Asteraceae family of plants were studied in vitro using LLC-MK2 and C6 glial cells. Agehoustin A was shown to be cytotoxic for both cells (71% or 67% cell death). Agehoustin B and artemetin, which lack a methoxy group at C-8 (RI), were not cytotoxic for the cells (19% and 16% cell death). The three flavonoids showed considerable suppressive effects on LLC-MK2 and C6 cell growth. Lucidin-dimethylether and gnaphaliin were also not cytotoxic for cells but they had no suppressive effect on cell growth. The results show a structure-cytostatic activity relationship. We suggest that the methoxy group on C-8 and on the B ring are responsible for death cell., (Copyright 2001 John Wiley & Sons, Ltd.)
- Published
- 2001
- Full Text
- View/download PDF
43. Phenol poisoning in three dogs.
- Author
-
Gieger TL, Correa SS, Taboada J, Grooters AM, and Johnson AJ
- Subjects
- Administration, Oral, Animals, Burns, Chemical pathology, Burns, Chemical therapy, Diagnosis, Differential, Dirofilariasis prevention & control, Dog Diseases pathology, Dog Diseases therapy, Dogs, Female, Gastric Mucosa drug effects, Gastric Mucosa pathology, Necrosis, Poisoning blood, Poisoning veterinary, Burns, Chemical veterinary, Dog Diseases chemically induced, Phenol poisoning
- Abstract
Three adult dogs were evaluated following oral administration of phenol by the owner. All three dogs experienced severe oral and gastric ulceration. Hematological abnormalities included neutropenia with the presence of toxic neutrophils, thrombocytopenia, and increased muscle enzymes. Endoscopic examination was performed, and biopsies yielded a diagnosis of gastric mucosal necrosis in two of the dogs. Following supportive care, the dogs recovered completely. Phenol is a caustic, highly poisonous derivative of coal tar. The dogs of this report were poisoned inadvertently by their owner who received misinformation concerning the use of this chemical via the Internet.
- Published
- 2000
- Full Text
- View/download PDF
44. Thyroid function and serum hepatic enzyme activity in dogs after phenobarbital administration.
- Author
-
Gieger TL, Hosgood G, Taboada J, Wolfsheimer KJ, and Mueller PB
- Subjects
- Adrenal Cortex Function Tests veterinary, Alanine Transaminase blood, Alkaline Phosphatase blood, Animals, Anticonvulsants therapeutic use, Cholesterol blood, Dog Diseases drug therapy, Dogs blood, Epilepsy drug therapy, Epilepsy veterinary, Liver enzymology, Liver Function Tests veterinary, Male, Phenobarbital therapeutic use, Reference Values, Thyroid Function Tests veterinary, Thyroid Gland physiology, Thyrotropin blood, Thyroxine blood, Anticonvulsants pharmacology, Dogs physiology, Liver drug effects, Phenobarbital pharmacology, Thyroid Gland drug effects
- Abstract
Phenobarbital is the drug of choice for control of canine epilepsy. Phenobarbital induces hepatic enzyme activity, can be hepatotoxic, and decreases serum thyroxine (T4) concentrations in some dogs. The duration of liver enzyme induction and T4 concentration decreases after discontinuation of phenobarbital is unknown. The purpose of this study was to characterize the changes in serum total T4 (TT4), free T4 (FT4), thyroid-stimulating hormone (TSH), cholesterol and albumin concentrations, and activities in serum of alanine aminotransferase (ALT), alkaline phosphatase (ALP), and gamma-glutamyl transferase (GGT) after discontinuation of long-term phenobarbital administration in normal dogs. Twelve normal dogs were administered phenobarbital at a dosage of approximately 4.4-6.6 mg/kg PO q12h for 27 weeks. Blood was collected for analysis before and after 27 weeks of phenobarbital administration and then weekly for 10 weeks after discontinuation of the drug. The dogs were clinically normal throughout the study period. Serum ALT and ALP activity and TSH and cholesterol concentrations were significantly higher than baseline at week 27. Serum T4 and FT4 were significantly lower. Serum albumin and GGT were not changed from baseline at week 27. Changes in estimate of thyroid function (TT4, FT4, TSH) persisted for 1-4 weeks after discontinuation of phenobarbital, whereas changes in hepatic enzyme activity (ALT, ALP) and cholesterol concentration resolved in 3-5 weeks. To avoid false positive results, it is recommended that thyroid testing be performed at least 4 weeks after discontinuation of phenobarbital administration. Elevated serum activity of hepatic enzymes 6-8 weeks after discontinuation of phenobarbital may indicate hepatic disease.
- Published
- 2000
- Full Text
- View/download PDF
45. Antiviral effect of flavonoids on the dengue virus.
- Author
-
Sánchez I, Gómez-Garibay F, Taboada J, and Ruiz BH
- Subjects
- Animals, Antiviral Agents toxicity, Cell Division drug effects, Cell Line, Cell Survival drug effects, Dose-Response Relationship, Drug, Flavonoids toxicity, Macaca mulatta, Antiviral Agents pharmacology, Dengue Virus drug effects, Flavonoids pharmacology
- Abstract
In the present study we analysed the possible antiviral effect on dengue viruses of different flavonoids extracted and identified at the Chemistry Institute, UNAM, from the Mexican plants Tephrosia madrensis, Tephrosia viridiflora and Tephrosia crassifolia. The flavonoids glabranine and 7-O-methyl-glabranine presented 70% inhibition on the dengue virus at a concentration of 25 microM, while methyl-hildgardtol A, hildgardtol A and elongatine had no effect on viral growth. Our results show that glabranine and 7-O-methyl-glabranine isolated from Tephrosia s.p. exert a dose-dependent inhibitory effect in vitro on the dengue virus., (Copyright 2000 John Wiley & Sons, Ltd.)
- Published
- 2000
- Full Text
- View/download PDF
46. Effects of long-term phenobarbital treatment on the liver in dogs.
- Author
-
Müller PB, Taboada J, Hosgood G, Partington BP, VanSteenhouse JL, Taylor HW, and Wolfsheimer KJ
- Subjects
- Administration, Oral, Animals, Chemical and Drug Induced Liver Injury, Enzyme Induction, Hypnotics and Sedatives pharmacology, Liver enzymology, Male, Phenobarbital pharmacology, Dog Diseases chemically induced, Dogs physiology, Hypnotics and Sedatives adverse effects, Liver drug effects, Liver Diseases veterinary, Phenobarbital adverse effects
- Abstract
Long-term administration of phenobarbital has been reported to cause hepatic injury in dogs. Phenobarbital induces hepatic enzymes, and it may be difficult to distinguish the effect of enzyme induction on serum liver enzyme activities from actual hepatic damage. The hepatotoxicity of phenobarbital and the impact of enzyme induction on serum liver enzyme activity were investigated prospectively in 12 normal dogs. Phenobarbital was administered for 29 weeks at 5 mg per kilogram of body weight (range, 4.8-6.6 mg/kg) PO q12h, resulting in therapeutic serum phenobarbital concentrations (20-40 microg/mL). Serum alkaline phosphatase (ALP), alanine transaminase (ALT), aspartate transaminase (AST), gamma-glutamyltransferase (GGT), fasted bile acids (fBA), total bilirubin, and albumin were determined before and during treatment. Lateral abdominal radiographs, abdominal ultrasounds, and histopathologic examinations of liver tissue obtained by ultrasound-guided biopsy were performed before and during treatment. Radiographs revealed a moderate increase in liver size in most dogs. Ultrasonographic examination revealed no change in liver echogenicity or architecture. No evidence of morphologic liver damage was observed histopathologically. ALP and ALT increased significantly (P < .05), GGT increased transiently, and albumin decreased transiently during the study. There were no significant changes in AST, bilirubin, and fBA. These results suggest that increases in serum ALP, ALT, and GGT may reflect enzyme induction rather than hepatic injury during phenobarbital treatment in dogs. Serum AST, fBA, and bilirubin, and ultrasonographic evaluation of the liver are not affected by the enzyme-inducing effect of phenobarbital and can therefore be helpful to assess liver disease in dogs treated with the drug.
- Published
- 2000
- Full Text
- View/download PDF
47. Effects of long-term phenobarbital treatment on the thyroid and adrenal axis and adrenal function tests in dogs.
- Author
-
Müller PB, Wolfsheimer KJ, Taboada J, Hosgood G, Partington BP, and Gaschen FP
- Subjects
- Adrenal Gland Diseases chemically induced, Animals, Hypnotics and Sedatives adverse effects, Male, Phenobarbital adverse effects, Pituitary-Adrenal System physiology, Thyroid Gland physiology, Thyrotropin analysis, Thyroxine analysis, Thyroxine metabolism, Dogs physiology, Hypnotics and Sedatives pharmacology, Phenobarbital pharmacology, Pituitary-Adrenal System drug effects, Thyroid Gland drug effects
- Abstract
Phenobarbital can interfere with the thyroid axis in human beings and rats by accelerating hepatic thyroxine metabolism because of enzyme induction. In human beings, it also can interfere with the low-dose dexamethasone suppression test (LDDST) used to assess adrenal function by accelerating dexamethasone metabolism. This effect can cause a lack of suppression of pituitary ACTH and subsequent adrenal cortisol release after dexamethasone administration. The effects of phenobarbital on the thyroid axis, the adrenal axis, and adrenal function tests were prospectively investigated in 12 normal, adult dogs. Phenobarbital was administered at 5 mg per kilogram of body weight (range, 4.8-6.6 mg/kg) PO q12h for 29 weeks, resulting in therapeutic serum concentrations (20-40 microg/mL). Serum total thyroxine (TT4), free thyroxine (FT4) by equilibrium dialysis, total triiodothyronine (TT3), thyrotropin (TSH), and cholesterol were determined before and during phenobarbital treatment. LDDST, ACTH stimulation tests, and ultrasonographic evaluation of the adrenal glands were performed before and during treatment. TT4 and FT4 decreased significantly (P < or = .05), TT3 had minimal fluctuation, TSH had only a delayed compensatory increase, and cholesterol increased during phenobarbital treatment. The delayed increase in TSH, despite persistent hypothyroxinemia, suggests that accelerated hepatic thyroxine elimination may not be the only effect of phenobarbital on the thyroid axis. There was no significant effect of phenobarbital on either of the adrenal function tests. With the methods employed, we did not find any effects of the drug on the hormonal equilibrium of the adrenal axis.
- Published
- 2000
- Full Text
- View/download PDF
48. Determination of normal values using an automated coagulation timer for activated coagulation time and its application in dogs with hemophilia.
- Author
-
Gerber B, Taboada J, Lothrop CD Jr, Busato A, Hosgood G, Goodman SA, and Gaschen FP
- Subjects
- Animals, Dog Diseases blood, Hemophilia A blood, Hemophilia A diagnosis, Partial Thromboplastin Time veterinary, Reference Standards, Reference Values, Reproducibility of Results, Sensitivity and Specificity, Dog Diseases diagnosis, Dogs blood, Hemophilia A veterinary, Whole Blood Coagulation Time veterinary
- Abstract
The present study was performed to determine normal values for the Medtronic HemoTec automated activated coagulation time (ACT) analyzer (Medtronic HemoTec Inc, Parker, CO, distributed in Switzerland by Convergenza AG, Vaduz, Liechtenstein), and to evaluate its ability to detect dogs with hemophilia. ACT was measured in 43 healthy dogs presented to the Companion Animal Hospital, University of Bern, Bern, Switzerland, with the Medtronic HemoTec ACT analyzer to determine normal values. The mean +/- 2 standard deviations (SDs) of the values obtained was defined as the normal range. ACT was measured 8-10 times on the same day in 6 dogs to determine repeatability. ACT also was measured in 11 dogs with hemophilia and compared with a conventional visual ACT measurement test and with the activated partial thromboplastin time (APTT). ACT values of the 43 dogs used to determine normal values ranged from 66.5 to 97.0 seconds (mean, 79.3 seconds; SD, 7.35 seconds; median, 78.5 seconds). A range of 64-95 seconds (mean +/- 2 SDs) was defined as the normal range for the tested device. Repeatability was poor (r = 0.256). ACT values measured with the automated device did not correlate with ACT values measured with a conventional visual test or with APTT Sensitivity of the test was 90.9%, specificity was 98.0%, and accuracy was 96.7%. Variability in the test results was large and may lead to incorrect results. The automated measurement device was not superior to the conventional visual method in evaluating dogs with hemophilia.
- Published
- 1999
- Full Text
- View/download PDF
49. Effects of oral administration of orotic acid on hepatic morphologic characteristics and serum biochemical variables in cats.
- Author
-
VanSteenhouse JL, Dimski DS, Taylor HW, Swenson DH, Taboada J, and Hosgood G
- Subjects
- Administration, Oral, Alanine Transaminase blood, Alkaline Phosphatase blood, Animals, Aspartate Aminotransferases blood, Cats, Creatinine urine, Fatty Liver chemically induced, Fatty Liver pathology, Female, Liver metabolism, Liver pathology, Orotic Acid administration & dosage, Orotic Acid toxicity, Creatinine blood, Liver drug effects, Orotic Acid pharmacology
- Abstract
Objective: To evaluate orotic acid (OA) as a possible etiologic factor in cats with idiopathic hepatic lipidosis (HL)., Animals: 20 clinically normal adult female cats., Procedure: Cats were fed a control diet or a diet containing less protein. On day 1 of the control period, blood, urine, and liver biopsy specimens were obtained. Each cat was given an oral dose of water daily. On days 8, 15, and 22, blood and urine specimens were collected as on day 1. On day 29, liver, blood, and urine samples were obtained as on day 1. After a resting period of 30 to 60 days, cats were treated with orotic acid. Serum biochemical analyses, urinary OA-to-creatinine ratios, and liver biopsy specimens were evaluated. Cats were given OA orally (suspension or capsules) for 29 days. Sample collection and data obtained were identical to those described for the control period., Results: Urinary OA-to-creatinine ratios were significantly higher in all treated cats, but ratios were significantly higher in those receiving OA in capsules than in those receiving OA in suspension. Diet or treatment did not alter hepatic biochemical or histologic variables significantly. However, 7 cats given the highest dose of OA in capsules developed azotemia, urolithiasis, and renal changes., Conclusions: Most concentrations of OA used in this study did not induce HL in cats during a 29-day period, but the highest dosage used did result in renal disease., Clinical Relevance: Orotic acid does not appear to be involved in the genesis of HL in cats.
- Published
- 1999
50. Urinary orotic acid-to-creatinine ratios in cats with hepatic lipidosis.
- Author
-
VanSteenhouse JL, Dimski DS, Swenson DH, and Taboada J
- Subjects
- Animals, Biomarkers urine, Cat Diseases urine, Cats, Chromatography, High Pressure Liquid, Fatty Liver diagnosis, Fatty Liver urine, Reference Values, Cat Diseases diagnosis, Creatinine urine, Fatty Liver veterinary, Orotic Acid urine
- Abstract
Objective: To determine urinary orotic acid (OA) concentration and evaluate the urinary OA-to-creatinine ratio (OACR) in cats with hepatic lipidosis (HL)., Animals: 20 cats with HL and 20 clinically normal cats., Procedure: Hepatic lipidosis was diagnosed on the basis of clinical signs, results of serum biochemical analyses, exclusion of other concurrent illness, and cytologic or histologic evaluation of liver biopsy specimens. Urine samples were collected from each cat and frozen at -20 C until assayed. Urine creatinine concentrations were determined, using an alkaline picrate method followed by spectrophotometric assay. Urine OA concentration was determined, using high-performance liquid chromatography. Minimum amount of detectable OA in feline urine was 1 microg/ml. Because of small interfering peaks near the base of the OA peak, the minimum quantifiable concentration of OA was determined to be 5 microg/ml. Urinary OACR was compared in both groups of cats., Results: Differences in urinary OACR were not detected between clinically normal cats and cats with HL. Peaks were not detected for urinary OA in any of the 20 clinically normal cats. Of the 20 HL cats, 14 did not have detectable peaks for urinary OA. Of the 6 HL cats that had detectable urinary OA peaks, 3 had values of <5 microg/ml., Conclusions: Apparently, OACR does not increase significantly in cats with HL., Clinical Relevance: Urinary OACR is not a useful diagnostic test for HL in cats.
- Published
- 1999
Catalog
Discovery Service for Jio Institute Digital Library
For full access to our library's resources, please sign in.