15 results on '"J Strecht"'
Search Results
2. Abordagem imagiológica dos aneurismas e dissecções da aorta. 2. Parte--Dissecções da aorta.
- Author
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J Strecht, I Amaral, J A Pereira, J Sanches, and A Gargaté
- Subjects
Medicine ,Medicine (General) ,R5-920 - Abstract
The authors review the main imaging findings of aneurysms and dissections of the aorta. Based on the experience and imaging techniques available in their institution (Conventional Radiology, Sonography and Computed Tomography), they try to make a decision tree of radiologic procedures in ambulatory and emergency patients. Nowadays, in the majority of situations, these techniques allow the Radiologist to make the correct diagnosis, detect the complications and evaluate the patients in the pre and post-surgical phases. Other imaging techniques not available in their institution, such as Magnetic Resonance Imaging and Aortography, will be mentioned in view of their usefulness in some specific situations.
- Published
- 1993
- Full Text
- View/download PDF
3. Abordagem imagiológica dos aneurismas e dissecções da aorta. 1a. Parte--Aneurismas da aorta abdominal.
- Author
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I Amaral, J Strecht, J A Pereira, J Sanches, and A Gargaté
- Subjects
Medicine ,Medicine (General) ,R5-920 - Abstract
The authors review the main imaging findings of aneurysms and dissections of the aorta. Based on the experience and imaging techniques available in their institution (Conventional Radiology, Sonography and Computed Tomography), they try to make a decision tree of radiologic procedures in ambulatory and emergency patients. Nowadays, in the majority of situations, these techniques allow the Radiologist to make the correct diagnosis, detect the complications and evaluate the patients in the pre and post-surgical phases. Other imaging techniques not available in their institution, such as Magnetic Resonance Imaging and Aortography, will be mentioned in view of their usefulness in some specific situations.
- Published
- 1993
- Full Text
- View/download PDF
4. P384 Lower infliximab trough levels are associated with higher bowel wall thickness in Crohn’s disease
- Author
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J Torres, Carolina Palmela, C Neto Nascimento, C Frias Gomes, J. Strecht, B Morão, and C Gouveia
- Subjects
Crohn's disease ,medicine.medical_specialty ,biology ,medicine.diagnostic_test ,business.industry ,C-reactive protein ,Gastroenterology ,Trough (geology) ,Computed tomography ,General Medicine ,medicine.disease ,Infliximab ,Internal medicine ,Area under curve ,medicine ,biology.protein ,Trough Concentration ,business ,medicine.drug ,Bowel wall - Abstract
Background Therapeutic drug monitoring (TDM) is currently used to optimise anti-TNFα therapy in Crohn’s disease, as higher infliximab trough levels (ITL) are associated with better rates of clinical remission and mucosal healing. Transmural healing is emerging as a potential target in Crohn′s disease, but whether there is any relation with ITL remains unclear. Here, we investigated the relation between ITL with bowel wall thickness (BWT) in patients with CD in maintenance therapy with IFX. Methods A retrospective cohort study of CD patients treated with IFX in mono or combination therapy. Patients were included if they had an available ITL during maintenance therapy and available entero-magnetic resonance or computerised tomography performed ±4 months. Transmural inflammation was defined as BWT ≥ 4 mm. Median BWT was measured in the most affected segment. An ROC curve was plotted to determine the best cut-off point of ITL to predict transmural inflammation. Mann–Whitney U-test, logistic regression and Spearman correlation were performed to assess the ITL relation with BWT. Results Twenty-nine patients were included (males 55.2%; mean age 39.6 ± 18 years; combo therapy 48.2%). According to the Montreal Classification, most patients were A2 (75.2%), with ileal (L1: 34.5%) or ileocolic disease (L3: 51.7%), and behaviour was: B1 41.4%, B2 24.1%, and B3 34.5%, with concomitant perianal disease in 37.9%. 82.2% were in clinical remission. The median IFX TL was 3.2 μg/ml (IQR 1.15–5.15) and median bowel wall thickness was 7 mm (IQR 4–9). 75.9% of patients had BWT > 4 mm. A BWT > 4 mm was associated with lower clinical remission rates (75% vs. 100%, p = 0.27) and higher C-reactive protein (0.31 vs. 0.14, p = 0.09), albeit not significantly. The area under the curve of ITL for bowel wall thickness was 0.70 (best cut-off value 1.8). Having ITL < 1.8 μg/ml was associated with higher median BWT (8.7 vs. 5.9 mm, p = 0.02) and was a predictive factor for transmural inflammation (OR 1.57, 95% CI [1.08–2.30], p = 0.02). BWT showed a fair correlation with ITL (r = −0.43, p = 0.02). Conclusion In our cohort of CD patients treated with infliximab (mono or combo therapy), lower infliximab trough levels were associated with higher bowel wall thickness, reflecting worse transmural inflammation. Proactive TDM could offer a possibility to improve BWT and reduce transmural inflammation.
- Published
- 2020
5. MON-P047: Lower Skeletal Muscle Radiation Attenuation is Associated with Stricturing or Penetrating Phenotype in Patients with Crohn's Disease (CD): An Exploratory Study
- Author
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Marília Cravo, Vickie E. Baracos, M.P. Santos, C. Palmela, S. Velho, J. Strecht, R. Cruz, and J Torres
- Subjects
Crohn's disease ,Pathology ,medicine.medical_specialty ,Nutrition and Dietetics ,business.industry ,Skeletal muscle ,Critical Care and Intensive Care Medicine ,medicine.disease ,Phenotype ,medicine.anatomical_structure ,medicine ,In patient ,business ,Radiation attenuation - Published
- 2016
6. MON-LB011: Predictors of Sarcopenia in Patients With Gastrointestinal Cancer
- Author
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F. Lopes, L. Agostinho, S. Velho, R. Cruz, J.P. Coelho, S. Moço, Marília Cravo, G. Luz, J.A. Teixeira, R. Maio, Vickie E. Baracos, T. E. Rodrigues, and J. Strecht
- Subjects
medicine.medical_specialty ,Nutrition and Dietetics ,business.industry ,Sarcopenia ,Internal medicine ,Medicine ,In patient ,Gastrointestinal cancer ,Critical Care and Intensive Care Medicine ,business ,medicine.disease ,Gastroenterology - Published
- 2015
7. [The imaging of acute pancreatitis. The current outlook]
- Author
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J, Strecht, P, Macedo, J L, Pereira, J, Sanches, and A G, Afonso
- Subjects
Pancreatitis ,Acute Disease ,Humans ,Tomography, X-Ray Computed ,Pancreas ,Ultrasonography - Published
- 1995
8. [Imaging of aortic aneurysms and dissections. Part 2. Aortic dissections]
- Author
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J, Strecht, I, Amaral, J A, Pereira, J, Sanches, and A, Gargaté
- Subjects
Aortic Dissection ,Humans ,Tomography, X-Ray Computed ,Aortography ,Magnetic Resonance Imaging ,Algorithms ,Aortic Aneurysm - Abstract
The authors review the main imaging findings of aneurysms and dissections of the aorta. Based on the experience and imaging techniques available in their institution (Conventional Radiology, Sonography and Computed Tomography), they try to make a decision tree of radiologic procedures in ambulatory and emergency patients. Nowadays, in the majority of situations, these techniques allow the Radiologist to make the correct diagnosis, detect the complications and evaluate the patients in the pre and post-surgical phases. Other imaging techniques not available in their institution, such as Magnetic Resonance Imaging and Aortography, will be mentioned in view of their usefulness in some specific situations.
- Published
- 1993
9. [Imaging of aneurysms and dissections of the aorta. Part 1--Aneurysms of the abdominal aorta]
- Author
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I, Amaral, J, Strecht, J A, Pereira, J, Sanches, and A, Gargaté
- Subjects
Aortic Dissection ,Aortic Rupture ,Humans ,Tomography, X-Ray Computed ,Magnetic Resonance Imaging ,Aortic Aneurysm, Abdominal ,Ultrasonography - Abstract
The authors review the main imaging findings of aneurysms and dissections of the aorta. Based on the experience and imaging techniques available in their institution (Conventional Radiology, Sonography and Computed Tomography), they try to make a decision tree of radiologic procedures in ambulatory and emergency patients. Nowadays, in the majority of situations, these techniques allow the Radiologist to make the correct diagnosis, detect the complications and evaluate the patients in the pre and post-surgical phases. Other imaging techniques not available in their institution, such as Magnetic Resonance Imaging and Aortography, will be mentioned in view of their usefulness in some specific situations.
- Published
- 1993
10. Dietary patterns and their relationships to sarcopenia in Portuguese patients with gastrointestinal cancer: An exploratory study.
- Author
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Velho S, Moço S, Ferreira A, Cruz R, Agostinho L, Cabral MS, Luz G, Lopes F, Teixeira JA, Strecht J, Coelho JLP, Maio R, Cravo M, and Baracos VE
- Subjects
- Aged, Body Mass Index, Diet statistics & numerical data, Diet Surveys, Feeding Behavior, Female, Gastrointestinal Neoplasms physiopathology, Humans, Logistic Models, Male, Middle Aged, Multivariate Analysis, Nutrition Assessment, Odds Ratio, Portugal, Principal Component Analysis, Prospective Studies, Risk Assessment, Risk Factors, Diet adverse effects, Gastrointestinal Neoplasms complications, Sarcopenia etiology
- Abstract
Objectives: The purpose of this exploratory study was to identify the main dietary patterns of a Portuguese population of patients with gastrointestinal cancer and to analyze their association with sarcopenia., Methods: This was a prospective study with a consecutive sample of 100 patients with gastrointestinal cancer enrolled at diagnosis. Dietary intake was assessed with a semiquantitative Food Frequency Questionnaire, and dietary patterns were obtained with principal component analysis. Nutritional assessment was done using the Patient-Generated Subjective Global Assessment, and body composition was evaluated with anthropometric measures and computed tomography image processing obtained at the third lumbar vertebrae. Sex and body mass index specific cutoffs were used to define sarcopenia., Results: Four major patterns were identified: high-fat dairy products, fried snacks, and processed meat diet; legumes, vegetables, and fruit diet; fat and fish diet; and alcohol, cereal, and animal protein diet. On simple logistic regression, the occurrence of sarcopenia in participants in the second tertile (odds ratio [OR] 0.30; 95% confidence interval [CI] 0.10-0.83; P = 0.02) and third tertile (OR 0.24; 95% CI 0.08-0.69; P = 0.01) of adherence to the high-fat and fish diet was reduced compared with the first tertile. On multiple logistic regression, the second tertile (OR 0.38, 95% CI 0.11-1.19; P = 0.10) of the fat and fish dietary pattern maintained a trend toward a reduction of the odds of sarcopenia compared with the first tertile, independently of calorie intake, age, disease location, and stage., Conclusions: The fat and fish dietary pattern was associated with lower odds of sarcopenia in this population of patients with gastrointestinal cancer., (Copyright © 2019 Elsevier Inc. All rights reserved.)
- Published
- 2019
- Full Text
- View/download PDF
11. Lower skeletal muscle attenuation and high visceral fat index are associated with complicated disease in patients with Crohn's disease: An exploratory study.
- Author
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Cravo ML, Velho S, Torres J, Costa Santos MP, Palmela C, Cruz R, Strecht J, Maio R, and Baracos V
- Subjects
- Adrenal Cortex Hormones therapeutic use, Adult, Body Mass Index, C-Reactive Protein metabolism, Crohn Disease complications, Crohn Disease drug therapy, Female, Humans, Male, Prognosis, Retrospective Studies, Sarcopenia etiology, Tomography, X-Ray Computed, Body Composition, Crohn Disease physiopathology, Intra-Abdominal Fat diagnostic imaging, Muscle, Skeletal physiopathology
- Abstract
Background and Aims: The prognostic value of body composition analysis in patients with Crohn's disease (CD) is poorly explored. The aims of the present study were to assess fat and skeletal muscle compartments including muscle radiation attenuation (MA) in patients with CD, and to analyze its predictive value to identify complicated phenotypes., Methods: Seventy one patients with CD who have had an abdominal CT within one month of clinical, laboratory, and endoscopic evaluation were included. Skeletal muscle area (SMA) and index (SMI), visceral fat area (VFA) and index (VFI), subcutaneous fat area (SFA), and mean MA were measured using appropriate software. Sarcopenia, as defined by Martin's criteria was assessed. Montreal classification was used to characterize disease phenotype., Results: Mean MA was lower in patients >40 years (p = 0.001), L2 (p = 0.09) and stricturing/penetrating disease (p = 0.03) whereas SMA and SMI were significantly lower in patients with positive C-reactive protein and previous hospital admissions (p < 0.01). On multivariate analysis, higher MA was protective against the complicated disease phenotype (stricturing/penetrating disease and/or previous surgeries) (OR 0.81; p = 0.002) whereas a high visceral fat index increased such risk (OR 26.1; p = 0.02). A ROC curve showed a 82.4% sensibility, 90.3% specificity, 17.6% positive predictive value, 9.7% negative predictive value and an area under the curve (AUC) of 0.91 for body composition analysis to predict complicated disease., Conclusions: A lower muscle attenuation and a high visceral fat index seem to be associated with more severe phenotypes in patients with CD., (Copyright © 2017 European Society for Clinical Nutrition and Metabolism. Published by Elsevier Ltd. All rights reserved.)
- Published
- 2017
- Full Text
- View/download PDF
12. Body Composition as a Prognostic Factor of Neoadjuvant Chemotherapy Toxicity and Outcome in Patients with Locally Advanced Gastric Cancer.
- Author
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Palmela C, Velho S, Agostinho L, Branco F, Santos M, Santos MP, Oliveira MH, Strecht J, Maio R, Cravo M, and Baracos VE
- Abstract
Purpose: Neoadjuvant chemotherapy has been shown to improve survival in locally advanced gastric cancer, but it is associated with significant toxicity. Sarcopenia and sarcopenic obesity have been studied in several types of cancers and have been reported to be associated with higher chemotherapy toxicity and morbi-mortality. The aim of this study was to assess the prevalence of sarcopenia/sarcopenic obesity in patients with gastric cancer, as well as its association with chemotherapy toxicity and long-term outcomes., Materials and Methods: A retrospective analysis was performed using an academic cancer center patient cohort diagnosed with locally advanced gastric cancer between January 2012 and December 2014 and treated with neoadjuvant chemotherapy. We analyzed body composition (skeletal muscle and visceral fat index) in axial computed tomography images., Results: A total of 48 patients met the inclusion criteria. The mean age was 68±10 years, and 33 patients (69%) were men. Dose-limiting toxicity was observed in 22 patients (46%), and treatment was terminated early owing to toxicity in 17 patients (35%). Median follow-up was 17 months. Sarcopenia and sarcopenic obesity were found at diagnosis in 23% and 10% of patients, respectively. We observed an association between termination of chemotherapy and both sarcopenia (P=0.069) and sarcopenic obesity (P=0.004). On multivariate analysis, the odds of treatment termination were higher in patients with sarcopenia (odds ratio=4.23; P=0.050). Patients with sarcopenic obesity showed lower overall survival (median survival of 6 months [95% confidence interval {CI}=3.9-8.5] vs. 25 months [95% CI=20.2-38.2]; log-rank test P=0.000)., Conclusions: Sarcopenia and sarcopenic obesity were associated with early termination of neoadjuvant chemotherapy in patients with gastric cancer; additionally, sarcopenic obesity was associated with poor survival., Competing Interests: Conflict of Interest: No potential conflict of interest relevant to this article was reported.
- Published
- 2017
- Full Text
- View/download PDF
13. [The imaging of acute pancreatitis. The current outlook].
- Author
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Strecht J, Macedo P, Pereira JL, Sanches J, and Afonso AG
- Subjects
- Acute Disease, Humans, Pancreas diagnostic imaging, Pancreatitis complications, Tomography, X-Ray Computed, Ultrasonography, Pancreatitis diagnosis
- Published
- 1995
14. [Imaging of aortic aneurysms and dissections. Part 2. Aortic dissections].
- Author
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Strecht J, Amaral I, Pereira JA, Sanches J, and Gargaté A
- Subjects
- Aortic Dissection classification, Aortic Dissection etiology, Aortic Aneurysm classification, Aortic Aneurysm etiology, Aortography, Humans, Magnetic Resonance Imaging, Tomography, X-Ray Computed, Algorithms, Aortic Dissection diagnosis, Aortic Aneurysm diagnosis
- Abstract
The authors review the main imaging findings of aneurysms and dissections of the aorta. Based on the experience and imaging techniques available in their institution (Conventional Radiology, Sonography and Computed Tomography), they try to make a decision tree of radiologic procedures in ambulatory and emergency patients. Nowadays, in the majority of situations, these techniques allow the Radiologist to make the correct diagnosis, detect the complications and evaluate the patients in the pre and post-surgical phases. Other imaging techniques not available in their institution, such as Magnetic Resonance Imaging and Aortography, will be mentioned in view of their usefulness in some specific situations.
- Published
- 1993
15. [Imaging of aneurysms and dissections of the aorta. Part 1--Aneurysms of the abdominal aorta].
- Author
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Amaral I, Strecht J, Pereira JA, Sanches J, and Gargaté A
- Subjects
- Aortic Dissection complications, Aortic Dissection diagnostic imaging, Aortic Aneurysm, Abdominal complications, Aortic Aneurysm, Abdominal diagnostic imaging, Aortic Rupture diagnosis, Aortic Rupture etiology, Humans, Magnetic Resonance Imaging, Tomography, X-Ray Computed, Ultrasonography, Aortic Dissection diagnosis, Aortic Aneurysm, Abdominal diagnosis
- Abstract
The authors review the main imaging findings of aneurysms and dissections of the aorta. Based on the experience and imaging techniques available in their institution (Conventional Radiology, Sonography and Computed Tomography), they try to make a decision tree of radiologic procedures in ambulatory and emergency patients. Nowadays, in the majority of situations, these techniques allow the Radiologist to make the correct diagnosis, detect the complications and evaluate the patients in the pre and post-surgical phases. Other imaging techniques not available in their institution, such as Magnetic Resonance Imaging and Aortography, will be mentioned in view of their usefulness in some specific situations.
- Published
- 1993
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