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Your search keyword '"J Reinoud Vermeijden"' showing total 2 results
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2 results on '"J Reinoud Vermeijden"'

1. Evolution of Costs of Inflammatory Bowel Disease over Two Years of Follow-Up.

Author

Mirthe E van der Valk, Marie-Josée J Mangen, Mirjam Severs, Mike van der Have, Gerard Dijkstra, Ad A van Bodegraven, Herma H Fidder, Dirk J de Jong, C Janneke van der Woude, Mariëlle J L Romberg-Camps, Cees H M Clemens, Jeroen M Jansen, Paul C van de Meeberg, Nofel Mahmmod, Andrea E van der Meulen-de Jong, Cyriel Y Ponsioen, Clemens Bolwerk, J Reinoud Vermeijden, Peter D Siersema, Max Leenders, Bas Oldenburg, and COIN study group and the Dutch Initiative on Crohn and Colitis

Subjects
Medicine, Science
Abstract

With the increasing use of anti-TNF therapy in inflammatory bowel disease (IBD), a shift of costs has been observed with medication costs replacing hospitalization and surgery as major cost driver. We aimed to explore the evolution of IBD-related costs over two years of follow-up.In total 1,307 Crohn's disease (CD) patients and 915 ulcerative colitis (UC) patients were prospectively followed for two years by three-monthly web-based questionnaires. Changes of healthcare costs, productivity costs and out-of-pocket costs over time were assessed using mixed model analysis. Multivariable logistic regression analysis was used to identify costs drivers. In total 737 CD patients and 566 UC were included. Total costs were stable over two years of follow-up, with annual total costs of €7,835 in CD and €3,600 in UC. However, within healthcare costs, the proportion of anti-TNF therapy-related costs increased from 64% to 72% in CD (p

Published
2016
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2. Risk factors of work disability in patients with inflammatory bowel disease — A Dutch nationwide web-based survey

Author

Mirthe E. van der Valk, Clemens J. M. Bolwerk, Martijn G.H. van Oijen, Marieke Pierik, Peter D. Siersema, Paul C. van de Meeberg, Dirk J. de Jong, Cyriel Y. Ponsioen, Jeroen M. Jansen, Bas Oldenburg, Herma H. Fidder, Ad A. van Bodegraven, J. Reinoud Vermeijden, Marie-Josée J. Mangen, Andrea E. van der Meulen-de Jong, C. Janneke van der Woude, Nofel Mahmmod, Max Leenders, Gerard Dijkstra, Mariëlle Romberg-Camps, and Cees H. M. Clemens

Subjects
medicine.medical_specialty, Crohn's disease, education.field_of_study, business.industry, Population, Gastroenterology, Prevalence, General Medicine, Logistic regression, medicine.disease, Ulcerative colitis, Inflammatory bowel disease, Quality of life, Internal medicine, medicine, Physical therapy, business, education, Cohort study
Abstract

Background Inflammatory bowel disease (IBD) is associated with high costs to society. Few data on the impact of IBD on work disability and potential predictive factors are available. Aim To assess the prevalence of and predictive factors for work disability in Crohn's disease (CD) and ulcerative colitis (UC). Methods A web-based questionnaire was sent out in seven university hospitals and seven general hospitals in the Netherlands. Initially, 3050 adult IBD patients were included in this prospective, nationwide cohort study, whereof 2629 patients were within the working-age (18–64 years). We used the baseline questionnaire to assess the prevalence rates of work disability in CD and UC patients within working-age. Prevalence rates were compared with the Dutch background population using age- and sex-matched data obtained from Statistics Netherlands. Multivariable logistic regression analyses were performed to identify independent demographic- and disease-specific risk factors for work disability. Results In CD, 18.3% of patients was fully disabled and 8.8% partially disabled, compared to 9.5% and 5.4% in UC patients (p Conclusion We report high work disability rates in a large sample of IBD patients in the Netherlands. CD patients suffer more frequently from work disability than UC patients. A combination of demographic and disease-related factors is predictive of work disability.

Published
2014
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