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We present a first study based on the analysis of the DEep Spectra of Ionized REgions Database (DESIRED). This is a compilation of 190 high signal-to-noise ratio optical spectra of HII regions and other photoionized nebulae, mostly observed with 8-10m telescopes and containing $\sim$29380 emission lines. We find that the electron density --$n_{\rm e}$-- of the objects is underestimated when [SII] $\lambda6731/\lambda6716$ and/or [OII] $\lambda3726/\lambda3729$ are the only density indicators available. This is produced by the non-linear density dependence of the indicators in the presence of density inhomogeneities. The average underestimate is $\sim 300$ cm$^{-3}$ in extragalactic HII regions, introducing systematic overestimates of $T_{\rm e}$([OII]) and $T_{\rm e}$([SII]) compared to $T_{\rm e}$([NII]). The high-sensitivity of [OII] $\lambda\lambda7319+20+30+31/\lambda\lambda3726+29$ and [SII] $\lambda\lambda4069+76/\lambda\lambda6716+31$ to density makes them more suitable for the diagnosis of the presence of high-density clumps. If $T_{\rm e}$([NII]) is adopted, the density underestimate has a small impact in the ionic abundances derived from optical spectra, being limited to up to $\sim$0.1 dex when auroral [SII] and/or [OII] lines are used. However, these density effects are critical for the analysis of infrared fine structure lines, such as those observed by the JWST in local star forming regions, implying strong underestimates of the ionic abundances. We present temperature relations between $T_{\rm e}$([OIII]), $T_{\rm e}$([ArIII]), $T_{\rm e}$([SIII]) and $T_{\rm e}$([NII]) for the extragalactic HII regions. We confirm a non-linear dependence between $T_{\rm e}$([OIII])-$T_{\rm e}$([NII]) due to a more rapid increase of $T_{\rm e}$([OIII]) at lower metallicities., Comment: Accepted for publication in MNRAS

We present MUSE deep integral-field unit spectroscopy of three planetary nebulae(PNe) with high abundance discrepancy factors (ADF > 20): NGC 6778, M 1-42 and Hf 2-2. We have constructed flux maps for more than 40 emission lines, and use them to build extinction, electron temperature (T$_e$), electron density (n$_e$), and ionic abundances maps of a number of ionic species. The effects of the contribution of recombination to the auroral [N II] and [O II] lines on T$_e$ and the abundance maps of low-ionization species are evaluated using recombination diagnostics. As a result, low T$_e$ values and a downward gradient of T$_e$ are found toward the inner zones of each PN. Spatially, this nearly coincides with the increase of abundances of heavy elements measured using recombination lines in the inner regions of PNe, and strongly supports the presence of two distinct gas phases: a cold and metal-rich and a warm one with "normal" metal content. We have simultaneously constructed, for the first time, the ADF maps of O$^+$ and O$^{2+}$ and found that they centrally peak for all three PNe under study. We show that the main issue when trying to compute realistic abundances from either ORLs or CELs is to estimate the relative contribution of each gas component to the H I emission, and we present a method to evaluate it. It is also found that, for the studied high-ADF PNe, the amount of oxygen in the cold and warm regions is of the same order., 20 pages, 10 Tables, 16 Figures. Additional material in appendix, 1 Table and 22 Figures. This article has been accepted for publication in MNRAS, Published by Oxford University Press on behalf of the Royal Astronomical Society

We use very deep spectra obtained with the Ultraviolet-Visual Echelle Spectrograph at the Very Large Telescope to derive physical conditions and chemical abundances of four H II regions of the Large Magellanic Cloud (LMC) and four H II regions of the Small Magellanic Cloud (SMC). The observations cover the spectral range 3100-10400 \A with a spectral resolution of $\Delta\lambda\ge\lambda/11600$, and we measure 95-225 emission lines in each object. We derive ionic and total abundances of O, N, S, Ne, Ar, Cl, and Fe using collisionally excited lines. We find average values of $12+\log(\mbox{O/H})=8.37$ in the LMC and $8.01$ in the SMC, with standard deviations of $\sigma=0.03$ and 0.02~dex, respectively. The S/O, Ne/O, Ar/O, and Cl/O abundance ratios are very similar in both clouds, with $\sigma=0.02$-0.03~dex, which indicates that the chemical elements are well mixed in the interstellar medium of each galaxy. The LMC is enhanced in N/O by $\sim0.20$~dex with respect to the SMC, and the dispersions in N/O, $\sigma=0.05$~dex in each cloud, are larger than those found for the other elements. The derived standard deviations would be much larger for all the abundance ratios, up to 0.20~dex for N/O, if previous spectra of these objects were used to perform the analysis. Finally, we find a wide range of iron depletions in both clouds, with more than 90 per cent of the iron atoms deposited onto dust grains in most objects., Comment: 34 pages, 10 figures. Accepted to be published in the Monthly Notices of the Royal Astronomical Society

Integral field spectroscopy (IFS) provides a unique capability to spectroscopically study extended sources over a 2D field of view, but it also requires new techniques and tools. In this paper, we present an automatic code, Spectroscopic Analysis Tool for intEgraL fieLd unIt daTacubEs, SATELLITE, designed to fully explore such capability in the characterization of extended objects, such as planetary nebulae, H II regions, galaxies, etc. SATELLITE carries out 1D and 2D spectroscopic analysis through a number of pseudo-slits that simulate slit spectrometry, as well as emission line imaging. The 1D analysis permits direct comparison of the integral field unit (IFU) data with previous studies based on long-slit spectroscopy, while the 2D analysis allows the exploration of physical properties in both spatial directions. Interstellar extinction, electron temperatures and densities, ionic abundances from collisionally excited lines, total elemental abundances and ionization correction factors are computed employing the Pyneb package. A Monte Carlo approach is implemented in the code to compute the uncertainties for all the physical parameters. SATELLITE provides a powerful tool to extract physical information from IFS observations in an automatic and user configurable way. The capabilities and performance of SATELLITE are demonstrated by means of a comparison between the results obtained from the Multi Unit Spectroscopic Explorer (MUSE) data of the planetary nebula NGC 7009 with the results obtained from long-slit and IFU data available in the literature. The SATELLITE characterization of NGC 6778 based on MUSE data is also presented., 20 pages, 20 figures, 7 tables, Accepted for publication in MNRAS

We present a reassessment of the radial abundance gradients of He, C, N, O, Ne, S, Cl, and Ar in the Milky Way using the deep optical spectra of 42 HII regions presented in Arellano-C��rdova et al. (2020, 2021) and M��ndez-Delgado et al. (2020) exploring the impact of: (1) new distance determinations based on Gaia EDR3 parallaxes and (2) the use of Peimbert's temperature fluctuations paradigm ($t ^ 2> 0$) for deriving ionic abundances. We find that distances based on Gaia EDR3 data are more consistent with kinematic ones based on Galactic rotation curves calibrated with radio parallaxes, which give less dispersion and uncertainties than those calibrated with spectrophotometric stellar distances. The distances based on the Gaia parallaxes --DR2 or EDR3-- eliminate the internal flattening observed in previous determinations of the Galactic gradients at smaller distances than $\sim 7$ kpc. Abundances and gradients determined assuming $ t ^ 2> 0 $ -- not only for O but also for the rest of elements -- are not affected by the abundance discrepancy problem and give elemental abundances much consistent with the solar ones for most elements. We find that our radial abundance gradient of He is consistent with the most accurate estimates of the primordial He abundance. We do not find evidence of azimuthal variations in the chemical abundances of our sample. Moreover, the small dispersion in the O gradient -- indicator of metallicity in photoionized regions -- indicate that the gas of the HII regions is well mixed in the sampled areas of the Galaxy., 20 pages, 9 figures

GATOS (GTC Astrophysical Transient Octuple-channel imaging Spectrograph) is a multi-channel imager and spectrograph capable of simultaneously obtaining images of the same field in 8 optical and near-infrared bands or alternatively performing spectroscopy covering the range between 3500 and 23500 Angstrom in a single shot at a resolving power of R ∼ 4000. State-of-the-art detectors envisioned for this instrument will have negligible readout times and be able to perform high-time-resolution observations. An integral-field mode covering the same range simultaneously will be a crucial element of the design. In its current design, the integral-field unit covers a field of 12" × 8" with 0.6" slitlets. Finally, we aim to include a unique spectropolarimetry unit that will give GTC the first broad-band spectropolarimeter on a 10 m class telescope. The design is an evolution of the OCTOCAM concept that was selected to be built at Gemini, and is now known as SCORPIO.

Non-traumatic small bowel perforation is rare in adults but carries a high morbidity and mortality. The diagnosis is made on clinical suspicion, and the most common causes in developing countries are infectious diseases, being cytomegalovirus infection in immunocompromised patients the main etiology. We describe a patient with a recently diagnosed advanced stage HIV infection and an intestinal perforation associated with cytomegalovirus immune reconstitution inflammatory syndrome after highly active antiretroviral therapy initiation., Highlights • Cytomegalovirus (CMV) is the main etiology of non-traumatic perforation of the small bowel in immunocompromised individuals. • We describe a case of CMV associated Immune reconstitution inflammatory syndrome. • To our knowledge this is the first case of small bowel perforation due to IRIS related CMV. • It is of importance for the clinician to consider CMV related IRIS as a cause of acute abdomen.

Streptococcus equi subsp. zooepidemicus infections are infrequent in humans. A clinical and epidemiological study of a milk-borne outbreak caused by this organism is described. Fifteen patients (5 females, 10 males) with a median age of 70 years (range 47–86) were infected. Twelve (80%) had underlying diseases. Infection with S. equi subsp. zooepidemicus presented as primary bacteremia in six cases, as bacteremia associated with aortic aneurism in four cases, as septic arthritis in two cases, as pneumonia in two cases, and as meningitis in one case. Five (33.3%) patients died. A case-control study proved that consumption of inadequately pasteurized cheese of a specific brand was associated with S. equi subsp. zooepidemicus disease (OR=4.5; 95% CI 1.57–19.27; p