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Your search keyword '"J F, SABATHIER"' showing total 4 results
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4 results on '"J F, SABATHIER"'

1. 9-pyridylidenefluorenes, a new class of anti-inflammatory substances

Author

P. Jacquignon, M. P. Sinh, J. F. Sabathier, N. P. Buu-Hoï, A. Rose, Delbarre F, and Brouilhet H

Subjects
Oral dose, chemistry.chemical_compound, medicine.drug_class, Prednisone, Chemistry, medicine, General Chemistry, Fluorene, Pharmacology, Anti-inflammatory, medicine.drug
Abstract

The condensation of fluorene with the three formylpyridines and 2-formyl-6-methylpyridine has been investigated, and the 9-pyridylidenefluorenes obtained have been tested in rats for anti-inflammatory activity. 9-(3-Pyridylidene)fluorene proved the most potent compound, with an activity half of that of subcutaneously injected prednisone, in an oral dose ten times greater.

Published
2010
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2. Notes

Author

J. H. Bowie, E. Bullock, A. W. Johnson, R. G. Cavell, H. C. Clark, I. J. Goldstein, W. J. Whelan, Frederick G. Mann, J. D. Loudon, G. Tennant, N. P. Buu-Hoï, P. Jacquignon, A. Rose, J. F. Sabathier, M. P. Sinh, R. D. Gillard, G. Wilkinson, R. B. Moodie, P. D. Wale, T. J. Whaite, K. J. van der Merwe, P. R. Enslin, K. Pachler, A. J. Birch, K. R. Farrar, S. J. Thomson, J. L. Wishlade, J. Casanova, R. E. Schuster, N. D. Werner, M. T. Chaudhry, R. Stephens, G. I. Fray, I. R. Beattie, M. Webster, H. Irving, and A. M. Kiwan

Published
1963
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