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Additional file 2: Figure 2. Sex and age related mean TC levels in 2001 and 2018 in a cohort restricting to first TC blood test ever (a), and including all blood test results regardless of multiple results per year (b).

Additional file 1: Figure 1. Mean deviation of TC from target value set by the external quality assessment organization from 2003 to 2018. Values are presented as deviation in percent with 95% CI. Data from 2001 to 2002 were not available.

Additional file 3: Figure 3. Annual trends in Non-HDL-C (a), sdLDL-C (b) levels from 2001 to 2018, and LDL-C calculated with the Sampson equation (c). Data are presented in mean values (mmol/L). Estimates are based on the first result each year, if multiple results per patient per year were available.