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OBJECTIVES: To evaluate the effect of lifestyle change programs on weight-loss and its maintenance in obese individuals. The trial sequential analysis (TSA) was applied to determine whether the currently available evidence is sufficient. METHODS: The PubMed, EMBASE and Lilacs databases were searched for randomized clinical trials published before May of 2018. Data were pooled using an inverse-variance random-effects meta-analysis and expressed as weighted mean differences (WMD) with 95% confidence intervals (CI). Heterogeneity was quantified and explored using subgroup analyses. RESULTS: Eleven trials (12 publications, 1416 participants) were considered eligible to be included in this meta-analysis. Caloric restriction was effective to promote weight-loss at 12 months [WMD − 3.79 kg (95%CI − 4.78 to − 2.79), I² = 87.5%] and 24 months [WMD − 6.20 kg (95%CI − 10.81 to − 1.59), I² = 71.2%] and TSA showed convincing evidence of an effect. At 36 months, there were no differences in body weight change [−2.06 kg (95%CI − 7.00 to 2.89), I² = 0.0%] and the meta-analysis included less patients than the required information size according to TSA. Subgroup analyses suggest improved weight-loss for caloric restrictions that are greater than 501 Kcal, Dietitian as the interventionist, intensity of intervention twice a month and dropout rates of

Pine nuts are the seeds of Araucaria angustifolia, which have a good nutritional value and relevance to be investigated in food technology, especially in bakery products for celiac people. This study aimed to evaluate physico-chemical and sensory properties of gluten-free breads made with pine nuts. Four different formulations (T1, T2,T3, and T4) of bread were prepared, varying the percentages flours, and were submitted to physical, chemical, and sensory analysis. The formulation made with pine nut and potato starch and the one made with pine nuts associated with potato starch and rice flour are promising alternatives for celiac patients.

Objective: to evaluate the effects of intervention program strategies on the time spent on activities such as watching television, playing videogames, and using the computer among schoolchildren. Sources: a search for randomized controlled trials available in the literature was performed in the following electronic databases: PubMed, Lilacs, Embase, Scopus, Web of Science, and Cochrane Library using the following Keywords randomized controlled trial, intervention studies, sedentary lifestyle, screen time, and school. A summary measure based on the standardized mean difference was used with a 95% confidence interval. Data synthesis: a total of 1,552 studies were identified, of which 16 were included in the meta‐analysis. The interventions in the randomized controlled trials (n = 8,785) showed a significant effect in reducing screen time, with a standardized mean difference (random effect) of: −0.25 (−0.37, −0.13), p